Regenerating composition for skin care

FIELD: medicine.

SUBSTANCE: invention relates to cosmetology and represents regenerating composition for skin care which contains regulator pH-triethanolamine, BAA, base Salcare SC80, cyclomethicone DC345, preservative, odorant, water, which is characterised by the fact, that as biologically active additive it contains protein substance from quail egg and antioxidant, and base includes UV-filter, olive oil, glycerin, emulsifier Solubilisant LRL preservative Sharomix MCI an purified water, and components in composition are in specified ratio in wt %.

EFFECT: invention ensures moistening and protection of skin from ultraviolet irradiation, as well as, regeneration, increase of tone and elasticity of skin.

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The invention relates to medicine, in particular to cosmetology. Regenerating the composition is intended to moisturize and protect against ultraviolet radiation using a UV filter, regeneration, improving tone and elasticity of the skin with protein biologically active substances obtained from quail eggs. The composition is made in the form of cream.

Known cosmetic cream (RF Patent No. 2298400, publ. 10.05.2007,) designed for effective care for normal and combination skin. The cream contains a mixture of ceteareth-6 and stearyl alcohol, stearic acid, triethanolamine, Cetearyl alcohol, fat mink, olive oil, lanolin, ethylhexyl methoxycinnamate, carbon dioxide chamomile extract, glycerin, perfume, propellant hydrocarbon, water. The cream allows you to achieve complex effects on the skin, including easy nanoselect cream, good absorption effect, giving skin a silky, moisturizing and nourishing the skin, strengthen the natural protective functions of the skin, prevention of inflammatory processes.

The disadvantage of the cream is the presence of lanolin is a well - known potential allergen, which also increases the viscosity of the formulation and affects the supply of oxygen to the skin.

Well-known cosmetic gel for face (RF Patent No. 2102975, publ. 27.01.1998, bull. No. 3), to the which contains as biologically active substances sodium salt of deoxyribonucleic acid, gelling copolymer based on acrylic acid, distilled glycerol or 1,2-propylene glycol, ethyl alcohol, triethanolamine, plasticizer selected from the group comprising perfume oil, butilstearat, isopropylmyristate, isopropyl, fragrance, preservative, dye, and water up to 100.0. Cosmetic gel also contains polyethylsiloxane fluid and ethoxylated lanolin. The gel has protivogerpeticheskiy, anti-spots, anti-oxidant action.

With all the advantages of the gel also has disadvantages: contains ethyl alcohol, which dries the skin.

Known cosmetic product (RF Patent No. 2185814, publ. 27.07.2002), which has a regenerative effect on the skin, containing biologically active additives, emulsifiers, antioxidants, preservatives, water-alcoholic extracts of plants, lavender essential oil, an oil component, kaolin and water. As a dietary Supplement contains dirt therapeutic sapropel in an amount of 0.1-80,0% by weight of the total funds. As emulsifiers cosmetic product contains components selected from the group of: stearic acid, triethanolamine, emulsion wax, taken in any interconnected relationships. As preservatives it contains components selected from the group: nipagin, polydon, as Cato.

One of the main disadvantages of this tool is the presence of parabens - preservatives that can cause skin cancers with long-term use.

Closest to the claimed invention is a Transdermal gel for face "STOLEN" (Patent RF №2376974, publ. 27.12.2009), containing a biologically active additives suspension by NRENs size up to 100 nm inclusive stem cell extract of pig placenta, hyaluronic acid, avocado oil, and the basis consists of acrylate emulsion copolymer Salcare SC80, cyclomethicone DC 345, preservative, perfume and brackish spring water for enhanced nutrition, hydration and skin regeneration. The gel has anti-inflammatory and moisturizing effect.

The disadvantage of the gel is the absence of UV filters, and as a result, protection from harmful UV exposure.

The purpose of the invention is hydration and protection against ultraviolet radiation using UV filters, regeneration, improving the tone and elasticity of the skin with protein biologically active substances obtained from quail eggs, added to the cream.

The technical result of the regeneration of the skin is achieved by means of a biologically active substance obtained according to the methodology, including homogenization quail eggs, okhlazhdennogo is at a temperature of 2-4°C and frozen at minus 20°C, dilution, filtering and tyndallization. Thus, before homogenization quail eggs incubated for 9 days, then cooled for 6 days at a temperature of 2-4°C, then eggs frozen for 24 hours at a temperature of minus 20°C. After homogenization, the homogenate was filtered through gauze filter and diluted with distilled water in the ratio 1:3, the obtained filtrate is again filtered through the filters, so that in substance remained substances of molecular weight less than 100 kDa, obtained substance subjected tindalizatsii at a temperature of 55°C for 5-6 days.

The technical result of protection from ultrafioletowego study is achieved by introducing into the cream UV filter, for example, Benzophenone-3, able to absorb UV radiation in the UVA and UVB spectra, which is especially important when damaged by an inflammatory process of the skin.

To prevent exposure of the skin to free radicals in the cream is made antioxidant, such as dihydroquercetin.

To enhance the nourishing and moisturizing properties of the cream in the recipe included olive oil, which also has excellent regenerative properties. Due to the high content of polyunsaturated fatty acids (oleic, palmitic, linoleic, palmitoleic) well restores the structure of the epidermis and improves water-holding t the WA skin.

To improve the distribution of the cream on the skin surface and remove its stickiness in the recipe entered cyclomethicone DC 345 (Dow Corning, USA). Using cyclomethicone based Cyclopentasiloxane improved organoleptic characteristics of the cream.

The moisturizing properties of the cream gives glycerin, which is a precursor of triglycerides, which is the structural part of the epidermis.

To obtain emulsions of oil and water-soluble components used emulsifier Solubilisant LRI - PPG-26-Buteth-26 (and) PEG-40 Hydrogenated Castor Oil.

A pleasant fragrance to the cream gives the odorant. To save the cream is put a water-soluble preservative, for example Sharomix MCI.

As the basis for a gel selected aqueous anionic acrylic emulsion copolymer Salcare SC 80 (INCI name: Steareth-lOAllyl Ether/Acrylates Copolymer), which is a carbomer. Salcare SC80 compatible with a wide range of cosmetic ingredients. Usually carbomer have a kind of white fine powder (Carbopol, Cosmedia SP), which must be subjected to a stage of swelling and dispersion. Salcare SC80 convenient to use due to its emulsified form to quickly get a clear cream.

Enablement of the claimed invention is confirmed by examples of specific performance.

Example 1.

The cream contains as biologically active additives to 3.0 wt.% is white the new substance of quail eggs, 1.0 wt.% antioxidant dihydroquercetin, and the basis consists of acrylate emulsion copolymer of 3.0 wt.%, cyclomethicone DC 345 10.0 wt.%, olive oil 15.0 wt.%, The UV-filter Benzophenone-3 to 10 wt.%, glycerin 3.0 wt.% triethanolamine 2 wt.%, preservative Sharomix MCI 0.05 wt.%, Solubilisant LRI 3.0 wt.%, perfume 0.1 wt.%, and purified water to 100 wt.%. Phase preparation and formulation of the cream is presented in table 1.

Phase A is prepared at room temperature by mechanical mixing of the components in the mixer. Phase B containing protein substance of quail eggs, are produced separately and entered into phase A with vigorous stirring. In order to stabilize the concentration of hydrogen ions (pH) to 6.6-7.2 and structure formation of the cream make the phase In (triethanolamine).

Cooked cream was applied on cleansed skin of face 1 time a day at bedtime. After 10 days of using the cream assessed the degree of keratinization and moisture. The maximum increase in the degree of keratinization was 10% and the moisture of 5% when the content of protein substances from quail eggs to 3.0 wt.%.

Example 2. Is similar to example 1, except that a protein substance from quail eggs to be paid in the amount of 5.0 wt.%. The composition of the base remains unchanged. The maximum increase in the degree of keratinization was 35% and the degree of C is znanosti 40% from the original values.

Example 3. Is similar to example 1, except that a protein substance from quail eggs to be paid in the amount of 7.0%. The composition of the base remains unchanged. The maximum increase in the degree of keratinization was 37% and the moisture of 43% from the original values.

Thus, the optimum is a cream made according to example 2, in which a protein substance from quail eggs to be paid in the amount of 5.0 wt.%. Further increase of the percentage of the substance of quail eggs did not lead to a significant increase in the degree of keratinization and moisturize the skin.

The prototype of the cream has passed pre-clinical trials in North-Caucasus Federal University. As a result of studies optimal percentage substance of quail eggs and auxiliary components to get the maximum increase in the degree of keratinization of skin moisture (table 2).

The claimed content of all components in the formulation of the cream optimally achieve the desired effect of skin regeneration and protection from ultraviolet radiation.

Thus, the claimed cream intensely moisturizes and protects the skin from ultraviolet radiation using a UV filter regenerates and improves the tone and elasticity of the skin with biologically active protein with whom stantsii, obtained from quail eggs.

Regenerating composition for skin care containing the pH Adjuster is triethanolamine, the BAD, the basis Salcare SC80, cyclomethicone DC345, preservative, perfume, water, characterized in that, as a dietary Supplement contains protein substance of quail eggs and antioxidant, and the base includes UV filter, olive oil, glycerine, emulsifier Solubilisant LRI, preservative Sharomix MCI and purified water, with the following content, wt.%: