Polyurethanes as agents modifying cosmetic product rheology

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to cosmetic industry and represents a cosmetic preparation containing water-dispersible polyurethane with linear main chains generally consisting of alternating hydrophilic and hydrophobic sections; herewith: a) both terminal sections (T) are hydrophibic and at least one of both sections (T) are a branched alkyl residue, b) a hydrophilic section (S) is attached to each section immediately (T), c) at least one hydrophobic section (D) is attached to at least one end of each section (S) immediately, and d) the main chain contains at least one hydrophilic section (P), if there are more than one sections (P) are provided, two sections (P) are divided by at least one hydrophobic section (D).

EFFECT: invention provides creating the cosmetic preparations having the improved viscosity maintained for longer periods of time.

9 cl, 13 ex, 4 tbl

 

The present invention relates to cosmetic preparations which contain the new type polyurethanes (PU) or a mixture of these polyurethanes primarily as a means of modifying the rheological properties of cosmetic products.

The present invention primarily relates to cosmetic preparations which contain water-dispersible polyurethane (PU) with a predominantly linear main chain composed of alternating hydrophilic and hydrophobic areas, and:

a) both end plot (T) hydrophobic,

b) directly to each plot (T) attached hydrophilic segment (S)

c) at least one end of each of the sections (S) directly attached to at least one hydrophobic region (D), and

d) main chain contains at least one hydrophilic segment (P), and if more than one plot (B) two sites (R) separated by at least one hydrophobic area (D)

and in the main chain of the polyurethane are at least three hydrophilic area and the ratio of the molecular weight of any of the hydrophilic areas (S) to the molecular weight of any of the hydrophilic areas (P) is in the range from 1:1.4 to 1:140, at least two hydrophobic segment (D) are aliphatic diisocyanate residues and at least Odie the hydrophilic segment (R) is the remnant of a polyether with a molecular weight of at least 1500 g/mol.

The polyurethane contained in the proposed invention in cosmetic preparations, are polymers, below also called polyetherurethane, which are formed by the interaction of alkoxysilane alcohols and/or simple polyether polyols with isocyanates or polyisocyanates. These polyurethanes below also indicate the abbreviation PU.

Under cosmetic interventions imply any changes in the skin and hair, implemented for aesthetic reasons or to cleanse the body. Cosmetic activities primarily involve body care, as well as the improvement and beautification of the appearance of a person that promotes optimum feel and allows you to make a good visual, tactile and olfactory impression on its environment, including loved ones.

In accordance with the present invention under cosmetic preparations include cosmetic formulations designed for hygienic and beauty care for your mouth.

In accordance with the present invention under cosmetic preparations include dermatological preparations.

Under the modification of the rheological properties of substances in the most General case imply a change of their deformation and fluid properties. The most important realogy the definition of the properties of substances are viscosity, the thixotropy, structural viscosity, rheopexy and dilatancy. These terms are well known to specialists.

Under the modification of rheology, in particular, imply the increase of viscosity of liquids, usually also known as thickening. This increase in viscosity may be accompanied by the formation of gels or solid phone

Water-dispersible polyurethanes which provide increased viscosity and, therefore, have the effect of thickeners, in principle, known.

To commonly used thickeners are complex monetary on the basis of fatty acid and polyethylene glycol, complex diesters based on fatty acids and polyethylene glycol, alkanolamide fatty acids, hydroxy-leaded aliphatic alcohols, ethoxylated esters on the basis of glycerol and fatty acids, ethers of cellulose, sodium alginate, polyacrylic acid (called in accordance with the International nomenclature of cosmetic ingredients (INCl) Carbonari, for example, different brands of the product Carbopol®)derived mouratov, polysaccharides and neutral salts such as sodium chloride.

However, depending on the subject thickening of drugs using the above conventional thickeners is associated with certain difficulties. For example, these thickeners may have not the enough thickening effect and poor stability with respect to salts, and their introduction to be thickening of the drug may be difficult. It is known that some thickeners, for example, sewn (hydrophobically modified) polyacrylic acid, neutralized state have an extremely high sensitivity to salts, surface-active agents or their mixtures, or interact with them. For example, the addition of salts can result in a sharp abrupt decrease in viscosity. Therefore, such polymers typically not used as thickeners, for example, in the formulations of shampoos. Due to the increased total concentration of salts in such formulations (surfactants, mixtures of surfactants, sodium chloride as a surfactant present in admixture) a significant increase in viscosity by the addition of conventional thickener may be missing. In the presence of cationic excipients may occur even complexation and precipitation. Thus, the search is suitable for use in the field of cosmetic preparations thickeners, which have a tolerance (resistance) against the salt and remaining in the presence of the latter optimal thickening abilities allow you to create drugs with favorable texture and pleasant the feeling when touching treated their skin and/or hair, is an extremely difficult task.

In addition, an important requirement for thickeners for cosmetic products is their compatibility with numerous other ingredients of cosmetic products, primarily salts and surfactants, as well as the absence of problems with their introduction in the composition of cosmetic products.

Rheological, physical and chemical properties of gelled cosmetic products must not significantly change in the conditions of long-term storage of drugs during the time components from several weeks to several months, at variable temperatures and pH values. Finally, such thickeners should be economical and should not have a significant negative impact on the environment.

Already in the late 70-ies in the application of the U.S. patent US-A-4079028 have been proposed so-called thickeners type HEUR (this abbreviation comes from the name "gidrofobizirovannym a non-ionic ethylene oxide urethane block copolymers"). Such thickener consists of a linear and/or branched polietilenglikolya blocks and hydrophobic segments, connected together as by means of urethane Grupp (in the case of using amines instead of the alcohols formed urea GRU is dust).

These HEUR-thickeners long used in a variety of fields, in particular, for thickening water-dispersion paints.

Saudade action HEUR-thickeners due to the fact that polietilenglikolya segments ensure their compatibility with water, while the hydrophobic segments due to Association with each other and containing buried particles of the binder to be thickening dispersion paints contribute to the formation of three-dimensional molecular structure, giving a dispersion paint required viscosity.

Preferred hydrophobic structural elements of the market HEUR-thickeners are typically long-chain monohydroxy alcohols, for example, n-octanol, n-dodecanol, isotridecyl alcohol, ISO-Nonylphenol or methyl ester of ricinoleic acid. Such alcohols are predominantly used as such or in the form of products of their accession to several equivalents of ethylene oxide.

It is used in the cosmetic field HEUR-thickeners primarily include the trademark Aculyn™ company Rohm & Haas (Aculyn™ 44 and Aculyn™ 46).

In U.S. patent US 4079028 and US 4155892 published linear polyurethane thickeners and their application in cosmetics. Obtaining mentioned polyurethane thickeners carried out in the presence of tin-containing catalysts of polymerization

From European patent EP 1013264 and EP 1584331-known cosmetic products that contain polyurethane thickeners and monatomic, respectively lower polyhydric alcohols. Polyurethane thickeners get one way by the ongoing mass without the use of catalysts interaction polyol, a poly-isocyanate and aliphatic alcohol, which if necessary can be amoxillian. According to the quoted publications in the case of changes in the concentration of salts containing these thickeners cosmetic preparation of its viscosity does not change.

In the European patent EP 1241198-described water-soluble or water-dispersible polyurethanes produced in one or several stages with respect to the ratio of NCO/OH groups in the range from 0.5:1 to 1.2:1 in the result of interaction:

A) a mixture of at least one simple polyetherpolyols A1) with an average functionality ≥3 and at least one containing urethane groups simple polyetherpolyols A2) with an average functionality ≥4,

B) at least one monohydroxy alcohol with 6-22 carbon atoms,

C) at least one (cyclo)aliphatic and/or aromatic diisocyanate,

D) optionally, at least one monoisocyanates with 4-18 carbon atoms, and

E) if necessary the value of at least one MDI with an average functionality of more than two.

In the international application WO 02/44236 describes cosmetic preparations containing polyurethane thickeners of the formula R1(CH2CH2O)n1CONH-X-NHCOO(CH2CH2O)mCONH-Y-NH-OC(OCH2CH2)n2OR2in which R1and R2respectively independently from each other mean a linear or branched, saturated or unsaturated alkyl residue with 6 to 22 carbon atoms and the number of double bonds, amounting to 0 and/or 1 to 3, the sum n1+n2 is 0 or a number from 1 to 100, m denotes a number from 4 to 500, as well as polyurethane thickeners of the formula -(CH2)z1-CR3R4]a1-[Ph]x-[CR5R6-(CH2)z2]a2in which R3, R4, R5and R6respectively independently of one another denote hydrogen or alkyl residues with 1 to 4 carbon atoms, Ph means optionally substituted by alkyl phenyl residue and x, A1, A2, z1 and z2 independently of one another denote 0 or 1.

In the international application WO 02/83093 describes cosmetic preparations containing polyetherurethane thickener of the formula R1-(OCH2CH2)m-[CO-NH-CH2-CH2-CH2-CH2-CH2-CH2-NH-CO]x-(CH2CH2O)n-R2in which R2respectively independently from each other mean a linear or branched alkylen the e and/or alkeneamine residue with 6 to 22 carbon atoms, x is a number from 1 to 3, m and n respectively and independently from each other mean a number from 10 to 100. Specified polyurethane thickener is intended for use in cosmetic preparations.

In the international application WO 2006/002813 As described polyurethane thickeners, intended for use in various water environments. Such thickeners derived from hydrophilic polyols containing at least two hydroxyl groups, one or more hydrophobic compounds, for example, long-chain alcohols, and at least bifunctional isocyanates. Using an excess of isocyanate groups. The catalyst used to obtain these thickeners may be tin or zinc-containing compound or amine.

From European patent EP V known polyurethane thickener, which is obtained by reacting polyether, resulting from alkoxysilane alcohols or alkyl phenols, with polyisocyanates, and the ratio of isocyanate groups to hydroxyl groups is in the range from 0.9:1 to 1.2:1. According to the cited document, the thickeners are encouraged to use in the range of low effort shift, for example, for filling water-dispersion paints.

The present invention was based on the objective of PR is dagiti cosmetic products with high viscosity rheological properties which do not significantly change over periods of time up to several weeks at low and high concentrations of the polyelectrolyte, as well as fluctuations in pH or temperature. Such cosmetic preparations, especially the corresponding emulsions and dispersions, must have stable chemical and physical properties. After Paraguana to the skin or hair treated with such cosmetic preparations should not be feeling oiliness or stickiness. In addition, these cosmetic products must have a maximum cosmetic and dermatological acceptability and above all must not contain compounds of tin.

The above problems according to the invention are solved by using a cosmetic preparation which contains water-dispersible polyurethane (PU) with a predominantly linear main chain composed of alternating hydrophilic and hydrophobic areas, and:

a) both end plot (T) hydrophobic,

b) directly to each plot (T) attached hydrophilic segment (S)

c) at least one end of each of the sections (S) directly attached to at least one hydrophobic region (D), and

d) main chain contains at least one hydrophilic segment (P, moreover, the presence of more than one plot (B) two sites (R) separated by at least one hydrophobic segment (D), and in the main chain of the polyurethane are at least three hydrophilic area, the ratio of the molecular weight of any of the hydrophilic areas (S) to the molecular weight of any of the hydrophilic areas (P) is in the range from 1:1.4 to 1:140, at least two hydrophobic segment (D) are aliphatic diisocyanate residues and at least one hydrophilic segment (R) is the remnant of a polyether with a molecular weight at least 1500 g/mol.

Used according to the invention the polyurethanes are water dispersible. According to the invention, the definition of "water-dispersible" means that the polyurethanes are capable of emulsification, as well as full or partial dissolution in water.

A preferred feature of the polyurethanes PU used in the proposed invention the preparations is their inherent ability to form aqueous dispersions concentration of from 0.1 to 10 g/l micelles with an average particle size of less than or equal to 200 nm, especially less than or equal to 100 nm (the size of the micelles was determined following the method of dynamic light scattering). Thus, these polyurethanes can be considered nanodispersions polymer is mi. In accordance with this critical micellization concentration (CMC) for the specified polyurethane is preferably less than 0.1 g/L.

The polyurethanes used in the present invention in drugs, mainly contain non-branched main chain, i.e. the branching last either absent or branching extremely rarely are distributed along the total length of the main chain. Such branches may have hydrophobic and/or hydrophilic parts of the polymer chains.

However, the polyurethanes used in the present invention, the preparations contain no zvezdoobraznykh branches or nodes of the spatial grid. Polyurethanes of this type, and receipt of them known from the prior art and are not relevant to the present invention.

The amount of branching in the molecules of the polyurethanes used in the present invention the preparations, preferably less than or equal to four, particularly preferably less than or equal to three. In accordance with a particularly preferred embodiment of the invention, the polyurethanes used in the present invention the preparations do not contain branching out end sections (T). Methods for the determination of branched™ polyurethanes, for example, a method of NMR spectroscopy, known to specialists.

Basically the chain polyurethanes, used in the proposed invention the preparations consist of alternating hydrophobic and hydrophilic sites, which may differ from each other in size, length and chemical nature. Hydrophilic plot both ends attached directly to the hydrophobic areas. These hydrophobic areas independently from each other may be the same or different. Each of the sections may be short-chained balance, and also oligomeric or polymeric residue.

This called hydrophilic parts of the polymer chain, which differ in a characteristic interaction with water. In General hydrophilic areas consist of residues of substances which are hydrophilic.

Well-known specialists typical hydrophilic groups are non-ionic residues of polyether. Preferred residues of polyether predominantly contain unbranched acceleratedly remains.

The remains of the polyether can be homoarginine residues or can be a mixture of different alkalinising residues. Such different acceleratedly residues can be statistically distributed in the residuals of polyethers or may be present in them as blocks. Preferred residues of polyethers are th catilinarian or homopiperazine residues. In accordance with another embodiment of the invention the remains of polyethers contain a mixture ethylenoxide and propylenoxide residues. The latter can be statistically distributed in the residuals of polyethers or may be present in them in the form of blocks.

In accordance with a particularly preferred embodiment of the invention the remains of polyethers containing at least 50 wt%. ethylenoxide residues: for example, they contain more than 50 wt%. ethylenoxide residues, as well as other alkalinizing residues propylenoxide residues. In an even more preferred embodiment, the remains of polyethers consist of ethylenoxide residues.

The degree of hydrophilicity of a substance can be installed, for example, by determining the turbidity of the aqueous solution.

The hydrophobic parts of the polyurethanes used in the present invention the drugs behave in relation to water quite differently than the corresponding hydrophilic areas. Hydrophobic areas in General consist of residues of substances which do not mix or badly mixed with water and usually lipophilic, that is highly soluble in non-polar solvents, fats and oils.

Typical hydrophobic groups include, for example, the R, hydrocarbon residues, primarily long-chain hydrocarbon residues. According to the invention preferred are linear or slightly branched hydrocarbon residues. According to one embodiments of the invention the hydrocarbon residues are unbranched. Examples of hydrophobic substances, the remains of which can be present in the hydrophobic areas of the polyurethanes used in the present invention the drugs are long-chain aliphatic alcohols, aromatic alcohols, and aliphatic diisocyanates.

Molecules that contain both hydrophobic and hydrophilic areas, generally referred to as amphiphilic molecules. Examples consisting of amphiphilic molecules of the substances are, in particular, phospholipids, emulsifiers and surfactants. A measure of hydrophilicity or other amphiphilic compounds is the hydrophilic-lipophilic balance. Figure hydrophilic-lipophilic balance proposed in the 20th century Griffin (Griffin W. S., Classification of surface active agents by HLB, J. Soc. Cosmet. Chem., 1, 1949), is used to estimate the ratio between the hydrophilic and lipophilic parts mainly non-ionic surface-active substances.

Figure hydrophilic-lipophilic balance can be calculated by the formula (I):

,

in which M1mean molecular weight of the hydrophobic parts of the molecules, whereas M denotes the molecular weight of the molecule as a whole. The factor of 20 is freely selectable multiplier Griffin. Figure hydrophiliclipophilic balance typically is in the range from 1 to 20. Figure 1 corresponds to a lipophilic compound, while the chemical compound with the index of the hydrophilic-lipophilic balance 20 is characterized by a high hydrophilicity.

Determined in accordance with the scale of the Griffin (from 1 to 20 units) figure hydrophilic-lipophilic balance of the polyurethanes used in the present invention the preparations, preferably greater than or equal to 7, particularly preferably greater than or equal to 14.

The polyurethanes used in the present invention, the preparations contain at least two terminal hydrophobic segment (Tons). The inner part of the molecules of the polyurethanes used in the present invention the preparations can be weakly branched (thanks optionally used small quantities of triisocyanate or polyisocyanates), with corresponding polymer chain may contain more than two terminal hydrophobic sections (T). While preferred are polyurethanes with unbranched inside nimi parts of the molecules, containing two terminal hydrophobic segment (Tons). Because hydrophobic areas (T) are located at the ends of molecules of polyurethane, they are directly attached only to one of the far section of the polyurethanes used in the present invention in the preparations.

The ends (T) polyurethanes may be the same or may differ from each other.

Terminal hydrophobic sections (T) of the above polyurethane may be branched or unbranched. In a preferred embodiment of the invention at least one of the two terminal hydrophobic stretch (T) of the polyurethanes used in the present invention the drugs is extensive.

Terminal hydrophobic sections T are preferably chains composed of carbon atoms. These chains preferably contain from 4 to 30 carbon atoms, particularly preferably from 6 to 26 carbon atoms and even more preferably from 8 to 20 carbon atoms.

Similar plots (T) can consist, for example, as from aromatic and alkyl residues. For example, parcels (T) may be a branched or unbranched alkyl residues or may contain a branched or unbranched alkyl residues. At least one segment (T) preferably is branched alkylene the balance. The definition of "branched" means that one or more of the carbon atoms of alkyl residue attached branching. Branching usually means alkyl, which in addition to members of the main chain contains one or more additional carbon atoms, covalently attached at one or two places to the carbon atom in the main carbon chain with the formation of the side chain. Side chains may be identical or may have different values. Themselves side chains preferably are alkyl or alkionovymi residues, particularly preferably alkyl residues, especially unbranched alkyl residues.

In one of the embodiments of the invention, the side chain alkyl residues preferably contain not more than six carbon atoms. In another embodiment of the invention, the side chains are preferably much shorter than the main chain. The length of each of the branching plots (T) polyurethanes used in the present invention the preparations, preferably does not exceed half the length of the main chain of these sections (T). Particularly preferred branched alkyl residues are isoalkyl and/or poucelina residues. The main chain alkyl residues, which consist of sections (T), prepact the tion contains from 4 to 30 carbon atoms, that is, under the appropriate main chain implies, for example, butane, pentane, hexane, heptane, octane, Nanan, decane, undecane, dodecane, tridecane, tetradecane, pentadecane, hexadecane, heptadecane, octadecane, nonadecane, Iksan, kanikosen, dokusan, triclosan, tetracosane, pentacosane, hexacosane, heptacosane, octacosane, nonacosane and/or triacetin. You can use branched alkyl residues, derivatives of these alkanes. In addition, you can also use residues derived cycloalkanes or alkenes. Plots (T) is particularly preferably contain alkyl residues with the number of carbon atoms from 6 to 26, e.g., residues of hexane, heptane, octane, nonane, decane, undecane, dodecane, tridecane, tetradecane, pentadecane, hexadecane, heptadecane, octadecane, nonadecane, ECOSAN, kanikosen, docosane, tricosane, tetracosane, pentacosane and/or hexacosane, and even more preferably they contain alkyl residues with the number of carbon atoms from 8 to 20, for example, the remains of octane, nonane, decanter, dodecane, tridecane, tetradecane, pentadecane, hexadecane heptadecane, octadecane, nonadecane and/or ECOSAN. You can also use branched alkyl residues, derivatives of these alkanes, as well as the remains of cycloalkanes or alkenes.

In a preferred embodiment, invented the I as branched alkyl residues using the remains of isoalkanes. Especially preferred is the alkyl residue with thirteen carbon atoms, especially saucily balance with thirteen carbon atoms.

Plots (T) can be introduced into the polyurethanes used in the present invention the drugs in different ways, for example, as part of the ethoxylated aliphatic alcohols.

The present invention also includes a cosmetic preparations containing a mixture of the above-described polyurethanes, terminal hydrophobic sections (T) which are branched and/or unbranched alkyl residues. Suitable for use in the proposed invention in cosmetic products are also mixtures, which contain the above-described polyurethanes as branched and unbranched terminal hydrophobic sections (T).

Directly to each of the sites (T) polyurethanes used in the present invention the drugs that are attached hydrophilic segment (S). Area (S) performs the function of a so-called separator. Area (S) should have a certain spatial flexibility. While preferred are unbranched hydrophilic areas (S).

Dividing the areas (S) of the polyurethanes used in the present invention the drugs, may be the same or can call the sterile from each other. In one of the embodiments of the invention use unbranched hydrophilic areas (S) of different length.

In another preferred embodiment of the invention the sections (S) of the polyurethanes used in the present invention, the preparations contain from 5 to 100 atoms, preferably from 6 to 90 atoms, particularly preferably from 8 to 80 atoms and especially from 15 to 60 atoms.

Areas (S) may contain acceleratedly residues. Areas (S) preferably contain from 2 to 30 alkalinising residue, especially preferably from 3 to 25 alkalinising residues, and even more preferably from 3 to 20 alkalinising residues.

At least two hydrophilic segment (S) of the above polyurethanes, respectively, can be ethylenoxide remains. In a preferred embodiment of the invention the hydrophilic areas (S) contain from 2 to 30 ethylenoxide residue, especially preferably from 3 to 25 ethylenoxide residues, and even more preferably from 3 to 20 ethylenoxide residues.

Areas (S) can also contain a mixture of ethylenoxide and propylenoxide residues or only propylenoxide remains.

Areas (S) can also contain longer acceleratedly remains, however, a set of sites (S) must have hydrophilicity, what can the t to be achieved, for example, by increasing the proportion present in ethylenoxide residues.

At least one end of each of the hydrophilic areas (S) directly attached to at least one hydrophobic region (D). The plot (S) may also be provided in the inner part of the molecule of the polyurethane used in the present invention the drugs. In such case, the plot (S) are not connected with one phase (D) and one plot (T) as the site (S)located on the edge of the molecules of the specified polyurethane, and at least two ends connected with sections (D). Moreover, with the relevant sections (D) is preferably connected to both ends located in the inner part of the molecule of section (S). Each of the sites (S), on the edge of the molecules of polyurethane, directly connected with the corresponding end plot (T).

In case of minor branching plot (S) he can be directly linked to the hydrophobic areas (D) in two or more places. Preferred option is, in accordance with which each unbranched hydrophilic separation site (S) with one or two ends adjacent one hydrophobic section (D).

In a particularly preferred embodiment of the invention, all of the areas (S), i.e. the first two sections (S), Vlada located on the edges of the molecules of the above polyurethane unbranched sections, each of which one end is attached to the land (T), and the other end to the plot (D).

The polyurethanes used in the present invention, the preparations contain at least two hydrophobic segment (D). Hydrophobic areas (D) may be the same or may differ from each other.

Plots (D) can be branched (may contain short-chained hydrophobic branching or unbranched. Plots (D) are preferably unbranched.

Plots (D) are preferably composed of carbon atoms of hydrophobic chains that contain from 2 to 20 carbon atoms, preferably from 3 to 16 carbon atoms and especially from 4 to 12 carbon atoms.

Plots (D) preferably contain diisocyanate residues. Plots (D) is particularly preferably contain residues of aliphatic diisocyanates. So, for example, hydrophobic region (D) may consist of one or more aliphatic diisocyanate residues. Plot (D) preferably contains from one to ten aliphatic diisocyanate residue, especially preferably from one to five aliphatic diisocyanate residue, even more preferably one, two or three aliphatic diisocyanate balance.

Hydrophobic areas (D) may contain aliphatic diisocyanate residues long and is officescape structural units, aliphatic structural units of medium length or short aliphatic structural units.

In one of the preferred embodiments of the invention under sections (D) of the polyurethanes used in the present invention the preparations involve cycloaliphatic or aliphatic diisocyanate residues. Plots (D) is particularly preferable are aliphatic diisocyanate remains.

With appropriate aliphatic diisocyanates are, for example, 1,4-butylenediamine, 1,12-dodecyltrimethoxysilane, 1,10-decamethylenediamine, 2-butyl-2-etilinlestradiola, 2,4,4-trimethylhexamethylenediamine or 2,2,4-trimethylhexamethylene-diisocyanate and primarily hexamethylenediisocyanate.

Examples of suitable cycloaliphatic diisocyanates are isophorondiisocyanate, 2-isocyanatopropyltrimethoxysilane, 4-methylcyclohexane-1,3-diisocyanate and 1,3-bis(isocyanatomethyl)cyclo-hexane. Plots (D) of the polyurethanes used in the present invention in the preparations, as residue can also contain so-called diisocyanate N12-DHS (in English literature they are called saturated MDI), such as 4,4'-Methylenebis(cyclohexyl-isocyanate) (also called dicyclohexylmethane-4,4'-diisocyanate or 2,4'-metilen the(cyclohexyl)diisocyanate.

Obviously, you can also use mixtures of the aforementioned diisocyanates, which allows to obtain a mixture of different polyurethanes used in the present invention in the preparations.

The polyurethanes used in the present invention, the preparations contain at least one hydrophilic segment (R). At least one end of the segment (P) is directly adjacent at least one hydrophobic region (D). Plots (B) of these polyurethanes may be the same or may differ from each other.

If the polyurethane used in the present invention, the preparations contain more than one hydrophilic segment (R), between such hydrophilic areas (P) is at least one hydrophobic region (D). In accordance with one embodiments of the invention between two hydrophilic areas (P) polyurethanes used in the present invention medications can be a sequence that includes a hydrophobic region (D), the hydrophilic segment (S), and then again hydrophobic region (D). Thus, if the polyurethane contains more than one segment (R), within its molecules can contain a sequence of sections P-D-P or P-D-S-D-P. if the polyurethane contains more than two sections (P), the molecule can be the consequences of the successive both of these types.

Each of the molecules of the polyurethanes used in the present invention the preparations preferably contain one or two areas (P).

Hydrophilic areas (P) preferably are predominantly unbranched residues of polyether, for example, polyalkyleneglycol. Hydrophilic areas (R) is particularly preferable are the remains simple polyetherdiols, especially polyethylene glycol. At least one hydrophilic segment (R) polyurethanes used in the present invention in the preparations is preferably formed of a polyethylene oxide.

According to the invention Brednikova molecular weight predominantly unbranched polyether residues, which form sections (P), is at least 1500 g/mol. In General Brednikova molecular weight of parcels (P) is, for example, up to 20000 g/mol.

In a particularly preferred embodiment of the invention Brednikova molecular weight predominantly unbranched residues of the polyether is in the range from 1500 to 12000 g/mol. Molecular mass plots (B) is particularly preferably equal to or less than 10000 g/mol and foremost is preferably from 4000 to 9000 g/mol. In an even more preferred embodiment, the molecular weight unbranched statcompiler polyesters greater than or equal to 6000 g/mol.

All hydrophilic areas of the polyurethanes used in the present invention the drugs, that is, as the areas (S)and plots (P)may be the remnants of polyethers.

In a preferred embodiment of the invention the hydrophilic areas of the polyurethanes used in the present invention the preparations consist of:

- polyalkylbenzene structural units (sections P) and

- polietilenoksidnoy structural units (parcels S).

In a particularly preferred embodiment of the invention all of the parts (P) and (S) of the polyurethanes used in the present invention the preparations consist of polietilenoksidnoy structural units.

The main chain of these polyurethanes mainly contains the remains simple polyesters and diisocyanates.

The polyurethanes used in the present invention, the preparations contain at least three hydrophilic area. In one of the preferred embodiments of the invention there are two sites (S) and at least one area (R).

In accordance with a particularly preferred embodiment of the invention, the polyurethanes used in the present invention, the preparations contain sequences parcels type T-S-D-P-D-S Is of type T or T-S-D-P-D-P-D-S-T.

The length of any of the sites (P) exceeds the length of ubago consisting of similar molecules separation plot (S).

The ratio of the molecular weight of any of the hydrophilic areas (S) of these polyurethanes to the molecular weight of any of the hydrophilic areas (P) is in the range from 1:1.4 to 1:140, preferably from 1:1.7 to 1:120. In a preferred embodiment of the invention the ratio is 1:x, with x equal to or greater than 2, preferably equal to or greater than 2.3 and particularly preferably equal to or greater than the 2.8. In a particularly preferred embodiment, the ratio ranges from 1:2.8 to 1:115, more preferably from 1:3 to 1:95 and especially preferably from 1:3.4 to 1:80.

The present invention relates to cosmetic preparations which contain the mixture used according to the invention polyurethanes. Such a mixture may consist of, for example, from polyurethane, containing the same sequence plots (T), (S), (D) and/or (B), however, sections of at least one of the specified types may structurally different from each other. It can be, for example, of different structure or different length sections like this. For example, in a mixture of polyurethanes may be present in different areas (T). In particular, in a mixture of polyurethanes contained in the proposed invention in cosmetic preparations can be present polyurethanes, both plots (T) which branched, polio many, both plots (T) which have a linear structure, and/or polyurethanes, which contain one non-branched section (T) and one extensive area (T). Such mixtures, obviously, can also contain other substances, for example, other preferred water-dispersible polyurethanes.

This mixture of polyurethanes can be obtained by using for the synthesis of polyurethanes used in the present invention the preparations, corresponding to different initial substances or their mixtures, or by subsequent mixing uniformly received these polyurethanes.

In accordance with one embodiments of the invention, the sum of molecular masses of all sites (T) and molecular mass plots (D) is less than or equal to the sum of molecular masses of all sites (R).

The polyurethanes used in the present invention the preparations can be obtained in the absence or preferably in the presence of at least one catalyst.

As catalysts can be used, for example, any commonly used in polyurethane chemistry catalysts.

Particularly preferably used catalysts, which have a solubility in organic solvents, such as xylene, toluene, acetone, tetrahydrofuran, butyl acetate, N-organic and/or N-ethylpyrrolidin.

As the organic metal compounds such as acids of Luisa can be used, for example, metal complexes, in particular, the acetylacetonates of iron, titanium, zinc, aluminum, cobalt, manganese, Nickel or zirconium such as zirconium-2,2,6,6-tetramethyl-3,5-galandia-NAT. Other suitable metal compounds described in the article Blank and others, Progress in Organic Coatings, 1999, 35, p.19 and following.

As catalysts it is possible to use bismuth, cobalt or zinc catalysts, as well as salts of cesium or titanium.

The polyurethanes used in the present invention in the preparations is preferably get in the presence of zinc and/or titanium containing compounds. These polyurethanes are particularly preferably get in the presence of at least one zinc carboxylate, at least one alcoholate of titanium(IV) or mixtures of these catalysts.

So, for example, as a catalyst used titanium alcoholate, preferably with two or more carbon atoms in the carbon chain. In a preferred embodiment of the invention the carbon chain of Ala is gostov titanium is 20 or less carbon atoms. The carbon chain of the titanium alcoholate, preferably contains from 3 to 18 carbon atoms. Especially preferred are the titanium alcoholate on the basis of aliphatic alcohols. In a particularly preferred variant of the invention, the polyurethanes used in the present invention the drugs get in the presence of Tetra-butyl ether orthotitanate acid, also known as butyl titanium(IV) or tetrabutoxide.

In a preferred embodiment of the invention as catalysts for use carboxylates of zinc, soluble in acetone, toluene, xylene and/or aliphatic hydrocarbons.

In another preferred embodiment of the invention, the polyurethanes used in the present invention the drugs produced in the presence of at least one carboxylate of zinc, the anions of which have the formula (CnH2n-1O2)-or (Cn+1H2n-2O4)2-in which n denotes a number from 1 to 20. In a particularly preferred variant of zinc salts as anions contain monocarboxylate General formula (CnH2n-1O2)-in which n denotes a number from 1 to 20.

The polyurethanes used in the present invention in the preparations is preferably get in the presence of zinc carboxylates which are aliphatic or aromatic carboxylates, and optionally may contain one or two ring structures.

In accordance with a particularly preferred embodiment of the invention for obtaining the above polyurethanes as catalysts preferably used carboxylates of zinc residues of carboxylic acids containing 20 or less carbon atoms, preferably 18 or less carbon atoms, particularly preferably 12 or less carbon atoms, because as the length of the carboxylate residues in accordance with the proposed invention by way of a reduction in catalyst activity.

In one of the embodiments of the invention as catalysts for polyurethanes used in the present invention the drugs, you can use the carboxylates of zinc, which do not have a ring structure. As catalysts for the synthesis of these polyurethanes are particularly preferably used aliphatic carboxylates of zinc.

As catalysts for the synthesis of the above polyurethanes even more preferably use 2-ethylhexanoate zinc (also known as octanoate zinc), n-octanoate zinc, n-decanoate zinc, neodecanoate zinc, ricinoleate zinc stearate and zinc. Especially preferred is the use of neodecanoate zinc.

As catalysts for polyurethanes used in th is used in the invention medications obviously, you can also use a mixture of two or more of the above catalysts. Preferably use only one catalyst.

The amount of catalyst does not play a significant role. In General the use of economically viable quantities of catalyst. Thus, the catalyst or mixture of catalysts preferably used in quantities of from 100 to 10,000 parts per million in terms of the initial simple polyetherdiol. The catalyst is preferably used in an amount of from 500 to 5000 parts per million, particularly preferably in the amount of 4,500 parts per million or less in terms of the total number of all original simple polyetherdiols. In a particularly preferred embodiment of the invention the catalyst is used in quantities of from 1000 to 3000 parts per million, calculated on the total number of all original simple polyetherdiols.

The catalyst (or catalysts), depending on its (their) features can be added in solid or liquid form or in dissolved state. Suitable solvents are unable to mix with water, organic compounds such as aromatic or aliphatic hydrocarbons, in particular toluene, xylene, ethyl acetate, hexane and cyclohexane, as well as esters of carboxylic acids, such as ethyl acetate. To the ome, suitable solvents include acetone, tetrahydrofuran, N-organic N-ethylpyrrolidin. It is preferable to use a catalyst (catalysts) in solid or liquid form. The catalyst preferably used in the form of a solution in a solvent, more preferably in the form of a solution in organic solvents, such as aliphatic hydrocarbons, acetone, toluene or xylene.

In a particularly preferred embodiment of the invention the catalyst (catalysts) used in the dissolved state.

In another particularly preferred embodiment of the invention, the catalyst used carboxylates of zinc dissolved in aliphatic hydrocarbons, acetone, toluene, xylene or optionally in mixtures of these solvents.

The polyurethanes used in the present invention the drugs, get the offer in the invention of the two-stage method. Upon completion of the second reaction stage, if necessary, perform the processing of the products obtained.

The synthesis of the above polyurethanes, in principle, can be carried out without using a catalyst, however, in the General case, receive the products with poorly reproducible characteristics (for example, srednetsenovoj and srednevekovoi molecular weight), about the eat case significantly increases the duration of synthesis and are often unable to provide the necessary viscosity of the respective aqueous preparations. In some cases, in the absence of a catalyst is an intensive education (high molecular weight) by-products of fusion. In this regard, the synthesis of the polyurethane is preferably carried out in the presence of at least one, particularly preferably in the presence of only one catalyst.

The advantage of the method of producing polyurethanes used in the present invention the preparations in accordance with this preferred option is the fact that the final product consists of molecules with the same structure, or contains a very specific mixture of polyurethane molecules.

In one of the embodiments of the invention is a method of obtaining polyurethanes used in the invention products includes the following stages:

1. the interaction of at least one simple polyetherdiol, molecular weight which is at least 1500 g/mol, of at least one aliphatic diisocyanate, carried out in the presence of at least one zinc carboxylate and/or at least one alcoholate of titanium,

2. the interaction of the obtained intermediate product with at least one ethoxylated aliphatic alcohol,

3. processing products of synthesis, that is usually feasible to remove all the PR is hanicheskih solvents and the transfer of the polymer in water.

The interaction of the original substance can be performed in solution. The interaction can be carried out in the melt, and in such case, the source of the substance or most of the initial substances are dissolved in a solvent condition.

In a preferred embodiment of the invention the synthesis of the polyurethane is carried out in two stages in the solution, and especially preferred is the dissolution of the starting materials in organic solvents, such as acetone, toluene or xylene.

In the first stage of the synthesis is preferably used most waterless simple polyspermia. Removing water from simple polyetherdiol can be accomplished by azeotropic distillation, drying under vacuum or other methods known in the art. So, for example, by azeotropic distillation, the water from simple polyetherdiol can be removed to a residual moisture content, which before serving diisocyanates is about 300 parts per million to Prepare simple polyetherdiol to the direct synthesis may be, for example, the following:

- removal of water to provide a sufficiently low residual moisture content (preferably about 300 parts per million or less by distillation under vacuum and subsequent mixing simple polyetherdiol with the solvent, or

- )is s simple polyetherdiol with the solvent, such as xylene, toluene or acetone, and removing water by subsequent azeotropic distillation, for example, to a moisture content of about 300 parts per million, however, the solvent removing incompletely, that allows to use a simple solution of the polyester in the remaining solvent for subsequent reactions in solution.

Before interaction with diisocyanates pH of a solution of diol in a solvent can be installed in the region of 7 or below and, if necessary, supererogate solution, for example, by desalting or the addition of an acid or a mixture of different acids. Thus it is possible to use inorganic or organic acids, such as hydrochloric acid, sulfuric acid, sulfurous acid, nitric acid, phosphoric acid, hydrofluoric acid, carbonic acid, organic acids, particularly malic acid, citric acid, oxalic acid, formic acid, acetic acid, propionic acid or butyric acid.

The degree of amoxilonline used ethoxylated aliphatic alcohols is preferably in the range of at least from 2 to 30, particularly preferably from 3 to 25 and more preferably from 3 to 20. In the most preferred embodiment, at least one of the used aliphatic alcohols is branched nonionic what Obedinenie, derived from isomeric saturated alcohol with 13 carbon of the formula RO(CH2CH2O)xH, in which R means an alkyl residue with 13 carbon atoms, preferably saucily balance with 13 carbon atoms, and x means 3, 5, 6, 6,5, 7, 8, 10, 12, 15 or 20, preferably 10 (commercially available products of BASF SE under the trade name Lutensol®TO, for example, the product Luten-sol®TO 10 if x means 10).

The molar ratio of the original simple polyetherdiols to the original diisocyanates may be in the range from 1:1.1 to 1:1.9 to. The specified molar ratio preferably ranges from 1:1.1 to 1:1.8 and. The specified molar ratio is particularly preferably in the range from 1:1.1 to 1:1,75. In the most preferred embodiment, the specified molar ratio is from 1:1.2 to 1:1,75. The specified relationship, obviously, may be 1:x, and x is a number greater than or equal to 1.3, preferably greater than or equal to 1.5.

In accordance with one embodiments of the invention in the molecules of the polyurethanes used in the present invention the preparations preferably have only one or two sites (R).

In accordance with a particular variant of the method of obtaining these polyurethanes in addition to the above ranges of ratios between simple Polief dialami and diisocyanates choose the proper molar ratio of the original simple polyetherdiols to the original ethoxylated aliphatic alcohols, which corresponds to the range from 5:1 to 1:2. The molar ratio of the original simple polyetherdiols to the original ethoxylated aliphatic alcohols is preferably in the range from 2:1 to 1:1,8, particularly preferably in the range from 1:1 to 1:1.6 and most preferably is 1:1,5.

In an even more preferred embodiment, the molar ratio between all three initial agents for the synthesis of the above polyurethanes, i.e. the molar ratio between simple polyetherdiols, diisocyanates and ethoxylated aliphatic alcohols is 1:1,75:1,5.

In addition, in the preferred proposed in the invention, the cosmetic preparations containing the above-described polyurethanes PU, water is present. Thus are preferred cosmetic preparations that contain at least 5% of the mass. first of all, at least 20% of the mass. even more preferably at least 30% of the mass. and most preferably at least 50 wt%. water. Under water-containing cosmetic preparations involve, for example, solutions, emulsions, suspensions or dispersions.

Preferred are proposed in the invention of drugs which are in addition used according to the invention the polyurethanes PU water and contain at least one salt or at least one surface is-active substance or surfactant mixture.

In accordance with the present invention under the surface-active agents include emulsifying agents, and mixtures of surface-active substances, emulsifiers. In accordance with the present invention under salt mean salt and solpadine patterns, including low pKSand mixtures thereof.

Especially preferred are proposed in the invention of drugs that in addition to the polyurethanes PU contain at least 0.05% wt. salt and/or at least 0.5% wt. surfactants, more preferably at least 0.1% of the mass. salt and/or at least 1% of the mass. surface-active substances.

In another embodiment of the invention the preparations in addition to these polyurethanes PU contain up to 20% of the mass. preferably up to 10% of the mass. and particularly preferably up to 5% of the mass. salt.

In another embodiment of the invention the preparations in addition to these polyurethanes PU contain up to 25% of the mass. preferably up to 20% of the mass. and particularly preferably up to 15% of the mass. surface-active substances.

In another embodiment of the invention the preparations in addition to these polyurethanes PU contain up to 10% of the mass. preferably up to 5% of the mass. salt, and up to 20%, preferably up to 15% of the mass. surface-active substances.

In accordance with another variant is sushestvennee of the invention use a salt-free system surface-active substances or systems of surfactants with low salt content.

In accordance with a particularly preferred embodiment of the invention, the preparations containing the above polyurethane PU, are emulsions of the type oil-in-water". In typical cases, the oil content in such emulsions of the type oil-in-water" is from 0 to 40 wt%. Preferred are emulsions of the type oil-in-water, oil content which is in the range from 5 to 40% wt. in particular in the range from 10 to 35% of the mass. and especially in the range from 15 to 30% of the mass.

Even more preferred are containing the above polyurethanes drugs, which are emulsions of the type oil-in-water containing at least one salt.

The content of the above polyurethanes PU in the proposed invention in cosmetic preparations is preferably from 0.01 to 10 wt%. preferably from 0.05 to 5% by mass and particularly preferably from 0.1 to 1.5% of the mass. in terms of the mass of the drug.

To prepare proposed in the invention of drugs which may be, for example, solutions, emulsions, suspensions or dispersions, use of the above polyurethanes PU, preferably in the form of aqueous dispersions which can be obtained by processing polyurethane after their synthesis, including, for example, removing the solvent, add the giving of water and, if necessary, add preservative and/or stabilizer.

In cosmetic or dermatological preparations is preferable to use the above polyurethanes PU, dynamic viscosity of aqueous dispersions which the 10% concentration. measured by the following method at the shear rate 100 1/s, is at least 100 MPa·s, especially preferably at least 200 MPa·s, even more preferably at least 300 MPa·S. When this aqueous dispersions of polyurethanes PU can behave as either Newtonian or as structurewise fluid. Dynamic viscosity structurebased dispersions of polyurethanes PU is preferably at least 1000 MPa·s, particularly preferably at least 3000 MPa·s (it is about measured following the method of the viscosity of aqueous dispersions of a 10% concentration. at the shear rate 100 1/s).

Experts know that many thickeners lose their inherent thickening efficiency in water-containing preparations, i.e. in case of the presence in the latter of salts and/or surfactants, viscosity decreases. In contrast, in the preferred embodiment of the invention, the polyurethanes PU ensure stabilization of the viscosity of the water-containing drugs also in the case of the addition of salts and/or surfactants.

In another variant is NTE embodiment of the invention the presence of the above polyurethanes PU in water-containing preparations which simultaneously contain at least one salt, unlike drugs, containing only salt or only the polyurethanes PU, allows you to maintain a nearly constant viscosity or even improve it. The sequence of adding the polyurethanes PU and salt is not significant.

Particularly preferred are the above-mentioned polyurethanes PU, which provide a high tolerance of water-containing preparations or enhancing their measured as described below, the dynamic viscosity, if such preparations contain at least one salt, at least one surfactant or preferably mixtures thereof.

Especially preferred is the use of the above polyurethanes PU, adding them to the water-containing preparations at a concentration in the latter salt, accounts for 0.5% of the mass. or more, leads to the stabilization of the measured, as described below, the dynamic viscosity. Especially preferred is the use of polyurethanes PU, which provide stabilization of the dynamic viscosity with the addition of 0.5% of the mass. or more of salt and 1% of the mass. or more surfactants, and the sequence of addition is not significant.

Especially preferred is the use of the above poly is ratanov PU, which increase measured, as described below, the dynamic viscosity of water-containing preparations, if the latter contain at least one salt, at least one surface-active substance or mixtures thereof. Especially preferred are polyurethanes PU, which provide increased measured, as described below, the dynamic viscosity of water-containing preparations at a concentration of 0.5% wt. or more. Especially preferred are polyurethanes PU, which provide increased dynamic viscosity compared with preparations containing less than 0.5% of the mass. preferably of 0.1% of the mass of salt, or less than 1% of the mass. preferably 0.5% mass. surface-active substances.

Even more preferred are the above-mentioned polyurethanes PU, which provide increased measured, as described below, the dynamic viscosity of water-containing preparations when the salt concentration of 0.05% of the mass. or more. Especially preferred are polyurethanes PU, which provide increased dynamic viscosity compared with preparations containing less than 0.05% of the mass. preferably 0.01% by mass. salt, or less than 0.5% of the mass. preferably of 0.1 wt% or less surfactant.

In one of the embodiments of the invention proposed in the invention of cosmetic the courthouse square contain at least 0.5% of the mass of at least one salt and at least 1% of the mass. at least one surface-active substance.

The foregoing polyurethane PU to the maximum extent does not depend on the charge density of, respectively, the ionic strength of other ingredients proposed in the invention of drugs. The effectiveness of the steps used according to the invention the polyurethanes PU comparable with the efficiency of monovalent or polyvalent ions.

The range of variation of pH

The above polyurethanes PU unlike many other rheology modifiers can be used in wide range of pH (2 to 12).

Another advantage of the polyurethanes PU is the formation of micelles in water. The critical micellization concentration (CMC) is the lowest possible concentration of a substance, in most cases, substances with hydrophobic and hydrophilic parts of the molecules, in which there is a spontaneous formation of micelles. Defined, as described below, the critical concentration of micelle formation of polyurethanes PU in water is preferably less than or equal to 1 g/l, particularly preferably less than or equal to 0.5 g/l, more preferably less than or equal to 0.25 g/l and even more preferably less than or equal to 0.1 g/L.

Another advantage of the proposed invention of drugs is preferable to use the W to obtain the above polyurethanes PU zinc and/or titanium containing catalysts. The manufacture of cosmetic preparations known from the prior art methods involving the use of tin-containing compounds, at present, is undesirable, since in this case the corresponding source products and made from them the drugs may contain tin. The presence of zinc-containing additives in cosmetic preparations, in contrast, is quite acceptable, and zinc due to its inherent anti-bacterial and anti-inflammatory properties can provide additional benefits.

The proposed invention in cosmetic or dermatological preparations contain at least one polyurethane PU and at least one cosmetically acceptable base.

Cosmetically acceptable base is preferably chosen from the group including:

i) water,

ii) miscible with water and organic solvents, preferably alkanols with 2-4 carbon atoms, especially ethanol,

iii) oils, fats, wax,

iv) different from (iii) esters on the basis of monocarboxylic acids with 6-30 carbon atoms and monatomic, diatomic or triatomic alcohols,

v) saturated acyclic and cyclic hydrocarbons,

vi) fatty acids,

vii) alifaticheskie spirits,

viii) working gases

ix) mixtures of the above substances.

To prednimustine acceptable bases include, for example, the hydrophilic base such as water, as well as monatomic and diatomic alcohols or spirits with greater atanasiu preferably 1-8 carbon atoms, such as ethanol, n-propanol, isopropanol, impregnated-lepicol, glycerin and sorbitol.

Diols

Particularly suitable hydrophilic bases are diols. Diols can be entered in the proposed invention in cosmetic preparations preferably in combination with polyurethane PU, which improves the efficiency of the latter. The preferred first and foremost is the use of propylene glycol in the presence of polyurethane PU. The preferred concentration used diol, preferably propylene glycol is from 1 to 10% of the mass. in terms of the total weight of the preparation.

Thus, another object of the present invention is proposed in the invention, the cosmetic preparations containing polyurethane PU and 1 to 10 wt%. at least one diol.

Proposed in the invention, the preparations may be in the form of aqueous or hydroalcoholic solutions, emulsions of the type oil-in-water (preferably) or water in oil", hydrodispersion recipes, recipes with stabilized solids, cosmetic pencils, formed at a temperature treatment phases of emulsions, creams, foams, sprays (manual restylene is or sprays), gels, gel sprays, lotions, oils, oil gels or mousses that supply usually present in these formulations excipients.

Under the proposed invention in cosmetic preparations involve cosmetic preparations for skin care, cosmetic preparations for the hair, as well as dermatological, hygienic or pharmaceutical drugs. The preferred forms of application proposed in the invention of drugs are gels, foams, sprays, ointments, creams, emulsion, suspension, lotion, milk or paste. Proposed in the invention of drugs if necessary, can also be used in the form of liposomes or microspheres.

Certain spray or flowable formulations in different forms of application can be prepared first by adding different amounts of polyurethane PU during or after preparation of such spray or flowable formulations.

In one of the embodiments of the invention first creates a low-viscosity cosmetic composition, which contains all other components. After adding all the necessary other components to regulate the desired viscosity. add the required amount of polyurethane PU. For example, a portion of the flowable formulations you need a kitchen is arranged in the form of spray without adding polyurethane PU, and another part by adding polyurethane PU can be prepared in the form of a lotion, but by adding additional quantities of polyurethane PU in the form of a cream. The need to control viscosity by additional homogenization in the case of subsequent additions polyurethane PU is absent, as in contrast to traditionally used thickening systems to achieve the desired effect is sufficient a single mixing. Therefore, the advantage of these polyurethanes PU is the possibility of establishing the necessary viscosity of cosmetic products, i.e. their viscosity can be adjusted by adding a thickener after the system already contains all components, except for the thickening agent.

Thus, used according to the invention polyurethane PU can be added during or after the preparation of the drug, which already contains all the usual prerequisites.

The proposed invention in cosmetic preparations in the form of emulsions of the type oil-in-water" or "water in oil" can be created by mixing the respective oil and water phases, one hot and the other cold, both cold phase or both phases are hot. When this hot call phase, the temperature of which is titsa in the approximate range from 70 to 80°C, while the cold phase is the approximate temperature of from 20 to 30°C.

Polyurethane PU can be located in the oil phase and/or in the aqueous phase, and in the preferred embodiment, it is in the aqueous phase.

The present invention preferably relates to cosmetic preparations selected from the group including gels, gel creams, jelly, hydrometalurgy, cosmetic pencils, cosmetic oils and oil gels, mascara and eyebrow, suntan products, care products skin care products and body care products skin after sunburn. According to the invention under cosmetic preparations include funds to care for the oral cavity.

Others proposed in the invention, the cosmetic preparations are preparations for skin care. It primarily concerns the creams of the type "water in oil" or "oil-in-water, day and night creams, creams for age, creams for skin care face creams anti-wrinkle creams for tightening the skin on the face, moisturizing creams, bleaching creams, vitamin creams, lotions for skin care and moisturizing lotions.

Other preferred proposed in the invention of drugs are cream Facials, cosmetic lotions and preparations for use in decorative cosmetics what their purposes, for example, such as a protective pencils, theatrical makeup, dye for eyelashes and eyebrows, eyeshadow, lipsticks, pencils Kayal (to create contour on the inner eyelid), brushes for drawing contour lines on the eyelids and around the eyes, make-up products, Foundation, blushers, powders and eyebrow pencils.

Other proposed invention medications include anti-acne, repellents, means for shaving, depilatories, means of personal hygiene, means for feet, as well as products for the care of children.

Other preferred proposed in the invention of drugs are tools for washing, shower and bath. In accordance with the present invention under the preparations for washing, shower and bath imply soap consistency from liquid to gel-like, such as transparent Soaps, soap class "Lux"soap-deodorant, cream Soaps, baby Soaps, Soaps for skin protection, abrasive Soaps and synthetic detergents, pasty Soaps, buttery Soaps and washing pastes, liquid preparations for washing, shower and bath, such as washing lotions, shower gels, milleporidae shampoos, oil and exfoliating preparations, as well as foams, lotions and shaving creams.

The following are additional ingredients suitable for use in the above offer is in the invention of the drugs.

The preferred proposed in the invention of drugs in addition to the above polyurethanes PU and the basis of the type specified above contain one or more cosmetically acceptable additives, such as emulsifiers and simulatory, solvents, surfactants, oil bases, preservatives, perfume oils, cosmetic active ingredients and substances for skin care, in particular, hydroxy acids, fruit acids, ceramides, Titan-triol, collagen, vitamins and provitamins, for example, vitamins a, E and C, retinol, bisabolol and panthenol, natural and synthetic svetoslava-catalysts natural substances, means to impart opacity, girotropnye soljubilizatory, repellents, bleaches, coloring tools, toners, tanning (for example, digidoc-Seaton), micropigment, such as titanium dioxide or zinc oxide, a means to increase the fat content of the skin, wax to impart a pearlescent luster, soljubilizatory, complexing agents, fats, waxes, silicone compounds, girotropnye, dyes, stabilizers, pH regulators, reflective additives, proteins and their hydrolysates (e.g., wheat protein, almond or peas), ceramide, protein hydrolysates, salt, gel-forming means, means for moistening the skin (e.g., 1,2-p is Tandil), means for recovering oily skin, UV filters, film-forming polymers, conditioning polymers, antioxidants, antispyware, softeners, plasticizers, peroxides and other commonly used in cosmetic preparations additives.

Antioxidants

Proposed in the invention of drugs in General preferably contain antioxidants. According to the invention as antioxi-duntov you can use any suitable for cosmetic use or commonly used antioxidants. Antioxidants suitable for use in the proposed invention in cosmetic preparations, see, for example, in international application WO 2006/106140 from line 12 on page 41 on the line 33 on page 42 inclusive. The specified text in full should be considered an appropriate reference.

Oils, fats and waxes

In a preferred embodiment of the invention proposed in the invention of drugs in addition to the above polyurethanes PU and cosmetically acceptable bases contain oil, fat and/or wax component selected from the group including:

hydrocarbons with minor polarity, such as mineral oils; linear saturated hydrocarbons, preferably containing more than eight carbon atoms, such as those who radican, hexadecan, octadecan and so on; cyclic hydrocarbons, such as decahydronaphthalene; branched hydrocarbons; animal and vegetable oils; waxes; ester waxes; vaseline; esters, preferably esters of fatty acids, such as esters on the basis of monohydroxy alcohols with 1 to 24 carbon atoms and monocarboxylic acids with 1-22 carbon atoms, in particular, isopropylacetate, n-profilerita, isopropylmyristate, n-propylvaleric, isopropyl-palmitate, hexacorallia, octacosanol, triacontanol-palmitate, dotriacontanol, tetratriacontane, hexacorallia, octacosane, treecontroller, duracon-canisters, tetratriacontane; salicylates, in particular, salicylates with 1-10 carbon atoms, for example, octisalate; benzoate, such as alkylbetaine with 10-15 carbon atoms in the alkyl and benzyl benzoate; other cosmetic acceptable esters, such as triglycerides of fatty acids, propilenglikolmonostearata, polietileno-colmanara, ancillotti with 10-15 carbon atoms in the alkyl, and mixtures of these compounds.

Oil or wax component may also be selected from the group comprising silicone oils and their derivatives, such as linear polydimethylsiloxane, poly(meth shall fenil)siloxanes, cyclic siloxanes and mixtures thereof. Brednikova molecular weight of polidi-methylsiloxane and poly(were)siloxanes preferably is in the approximate range from 1000 to 150000 g/mol. Preferred cyclic siloxanes contain rings with the number of members from 4 to 8. Suitable cyclic siloxanes are commercially available, for example, under the trade name of cyclomethicone.

The preferred oil, respectively fatty components chosen from the group comprising paraffin and paraffin oils; vaseline; natural fats and oils such as castor oil, soybean oil, peanut oil, olive oil, sunflower oil, sesame oil, jojoba oil, avocado oil, cocoa butter, almond oil, peach oil, castor oil, fish oil, lard, spermaceti, spermaceti oil, spermaceti fat, oil from wheat germ oil of Australian walnut, Kyprianou oil and jojoba oil; aliphatic alcohols, such as lauric alcohol, ministerului alcohol, cetyl alcohol, stearyl alcohol and alerby alcohol; fatty acids such as myristic acid, stearic acid, palmitic acid, oleic acid, linoleic acid, linolenic acid and different from them saturated, unsaturated and substituted fatty acids; waxes, such as beeswax, Carnauba wax, candrilli the s wax and spermaceti, as well as a mixture of the above oil and fat components.

Suitable cosmetically and pharmaceutically compatible oil and fat respectively components are also given in the Handbook Karl-Heinz Schrader, Grundlagen und Rezepturen der Kosmetika, 2nd edition, publisher Huthig, Hedelberg, cc.319-355, which should be considered by an appropriate reference.

Preferred are oils, fats and/or waxes, are given in the text with a line 39 to pp.28 on the line 22 on p.34 inclusive international application WO 2006/106140. The specified text in full should be considered an appropriate reference.

The content of oils, fats and waxes does not exceed 80% of the mass. preferably does not exceed 50% of the mass. more preferably does not exceed 30% of the mass. in terms of the total weight proposed in the invention of the drug.

Surfactants

Preferred cosmetic preparations in addition to the above polyurethanes PU and at least one cosmetically acceptable base, which preferably use water, also contain at least one surfactant. As surface-active substances it is possible to use anionic, cationic, nonionic and/or amphoteric surfactants.

In accordance with the present invention the preferred anionic detergent surfactants are the following compounds (here and in the far is our description of the PEG means polyethylene glycol, BCP polypropylenglycol):

- acylaminoalkyl and their salts, such as acellularity, primarily sodium acellular,

- sarcosinate, for example, myristoyl sarcosine, triethanolamine lauroyl of sarcosinate, sodium lauroylsarcosinate and sodium cocoylisethionate,

- sulfonic acids and their salts, such as utilizationin, for example, sodium cocoylisethionate or ammonium cocoylisethionate,

- sulfosuccinate, for example, dictionary sulfosuccinate, disodium laurilsulfosuktinat, disodium laurilsulfate, dinat-nical undecided amidomethyl sulfosuccinate, disodium PEG-5 laurylsarcosine and derivatives thereof,

- alkylsulfonates, for example, sodium Laureth sulfate, ammonium Laureth sulfate, magnesium Laureth sulfate, monoisopropylamine Laureth sulfate, triisopropanolamine Laureth sulfate, sodium myresult and sodium With12-13paritcular,

the alkyl sulphates, such as sodium laurylsulfate, ammonium laurylsulfate and triethanolamine laurylsulfate.

Other preferred anionic surfactants are:

- taurate, for example, sodium laureillard and sodium methylcobalamin,

- ethers, carboxylic acids, for example sodium Laureth-13 CT-boxill, sodium PEG-6 cocamide carboxylate and sodium PEG-7 olive oil carboxylate,

the esters and salts of phosphoric acid, such as diethylamine IG-1 phosphate and delaure-4 phosphate,

the alkyl sulphonates, such as sodium cohomologically, sodium12-14reincorporate, sodium laurylsulfate and magnesium PEG-3 karamitsuita,

- acellularity, such as detritally of Palmitoyl aspartate and sodium Caprylic/capric glutamate,

- elliptic, for example, Palmitoyl hydrolyzed milk protein, sodium, Cocoyl hydrolyzed soya protein and sodium/potassium Cocoyl hydrolyzed collagen,

as well as carboxylic acids and their derivatives, such as lauric acid, aluminum stearate, Alkonost magnesium and underinvest zinc, esters of carboxylic acids, for example, calcium stearylamine, Laureth-6 citrate and sodium PEG-4 lauramidopropyl,

- alkylarylsulfonate.

The preferred embodiment of the invention relates to cosmetic preparations which contain at least one of the above polyurethane PU, at least one hydrophobic modified phosphate and/or at least one hydrophobic modified sulfate.

Examples of suitable hydrophobically modified phosphates are Luviquat®Mono CP (named according to the nomenclature INCl hydroxyethyl of atildigini phosphate), Luviquat®Mono LS (named according to the nomenclature INCl of catrimani methosulfate) and the products of the brand Amphisol®(the name but according to what enclature INCl cetilistat, potassium cetilistat), whereas an example of a suitable hydrophobic modified sulfate is Lanette®E (named according to the nomenclature INCl sodium clearesult).

The use of such hydrophobic modified phosphates and/or sulfates in combination with the above polyurethanes PU leads to additional increase in viscosity. The increased viscosity is maintained also when the temperature of the drug.

In a preferred embodiment, the mass ratio of polyurethane PU to hydrophobic modified phosphate and/or hydrophobic modified sulfate is in the range from 0.5:1 to 2:1, preferably from 0.8:1 to 1.2:1.

Preferred cationic detergent surfactants in accordance with the present invention are Quaternary surfactants. The latter contain at least one nitrogen atom, covalently linked to four alkyl or aryl groups. Preferred cationic detergent surfactants are, for example, alkylbetaine, alkylamidoamines and alkilamidopropildemetilaminobetain.

Other preferred cationic surfactants in accordance with the present invention are:

- alkylamines followed,

- alkylimidazole and

- ethoxylated amines,

and especially their salts.

In accordance with the present invention the preferred detergent is amphoteric surfactants are acyl-/dialkylacrylamide, for example, sodium etilamfetamine, disodium etilamfetamine, disodium alkylimidazole, sodium asylumpolicyinstructions, disodium etilamfetamine, sodium allimportant, as well as sodium salt amidoethyl-n-hydroxymethylglycinate n-fatty acids of coconut oil.

Other preferred amphoteric surfactants are n-alkylamino-acid, for example, aminopropylmorpholine, alkylenediamines acid, sodium alkylenediamines and Eurointernational.

In accordance with the present invention, preferred nonionic detergent surfactants are the following connections:

- alkanolamide, such as cocamide monoethylamine/diethylamine/mono-Isopropylamine,

- esters resulting from the esterification of carboxylic acids with ethylene oxide, glycerol, sorbitan or other alcohols,

- ethers, for example ethoxylated alcohols, ethoxylated lanolin, ethoxylated polysiloxane, propoxyimino-EN polyoxyethylene esters, alkylpolyglycoside, such as laurelhouse, decollimated and cocoglucoside, glycosides with indicator hydrophilic-lipophilic balance of at least 20 (e.g., the product Belsil®SPG 128V Wacker).

Other preferred nonionic surfactants are alcohol and aminoxide, such as cocamidopropylbetaine.

<> Preferred anionic, amphoteric and nonionic surfactants are listed, for example, pages 131-134 "Kosmetik and Hygiene von Kopf bis Fuβ", W.Umbach (publisher), 3 edition, Wiley-VCH, 2004, which in full should be considered an appropriate reference.

The preferred alkylsulfonate primarily are alkylsulfonates sodium based on twice or three times ethoxylated lauric or miristinovoi alcohol. This alkylsulfonates significantly exceed the corresponding alkyl sulphates in relation to sensitivity to water hardness, and the ability to thickening, solubility in cold and especially compatibility with skin and mucous membranes. They can also be used as a universal detergent ingredient shampoos. Laurylsulphate compared with meisterschaften has better foaming properties, but inferior to the latter in terms of softness.

Alkylaminocarbonyl who have average and particularly high softness, are the most soft surface-active substances, however, charcterized poor foaming and viscosity properties. They are often used in the media to wash your hair in combination with alkylsulphonate and amphoteric surfactants.

Esters sulfonterol acid (sulfasalzine the s) are soft and effective foaming surfactants, however, due to unsatisfactory thickening ability is preferably used only in combination with other anionic and amphoteric surfactants, and because of the poor resistance to hydrolysis, preferably only in neutral shampoos or shampoos with a pH securely stabilized in an appropriate buffer.

Aminopropylation have a negligible practical value as a universal detergent raw material, because they differ moderate foaming and thickening ability. At the same time, these surfactants have excellent compatibility with skin and mucous membranes. Their softness synergistically increases in the case of use in combination with anionic surfactants. Preferred is the use of cocamidopropylbetaine.

Atacamite/apodicticity as amphoteric surfactants have an extremely high compatibility with the skin and mucous membranes and can be conditioning effect, respectively, to increase the efficiency intended for hair care supplements. Like betaines these surfactants are used for optimization of the formulation containing alkylsulfonates. The most preferred compounds of the specified type are sodium cocoamphoacetate and the disodium cocoamphodiacetate.

Alkylphenolic side belong to the non-ionic detergent raw materials. They are soft surfactants universal actions, however, are characterized by poor foaming ability. In this regard, they are preferably used in combination with an anionic surfactant.

Esters of sorbitol and belong to the non-ionic detergent raw materials. They have excellent softness, which are preferably used in baby shampoos. Due to the low foaming action esters of sorbitol is preferably used in combination with an anionic surfactant.

According to the invention, it is preferable to use one or more of the above surfactants in a concentration of from 0.1 to 30% wt. preferably from 1 to 25 wt%. more preferably from 5 to 25% of the mass. and even more preferably from 10 to 20% of the mass. accordingly, calculated on the total weight of the preparation.

Turning on the air

Another advantage of cosmetic products containing the above polyurethanes PU, is that you can enter up to 150%. air in terms of the amount of the drug prior to the introduction of air. Thus, another object of the present invention is proposed in the invention is a cosmetic product which can be prepared by the method in accordance with which already contains all the other components what s the drug is administered from 5 to 150%. air in terms of the amount of the drug prior to the introduction of air. Such preparations contain from 5 to 150% by vol., preferably from 20 to 100% vol. air, are other objects of the present invention. Proposed in the invention, the preparations containing from 5 to 150%. air in terms of the amount of the drug prior to the introduction of air to maintain a constant volume in a few months. The introduction of air into the product ensures the optimization of its structure (the narrower the distribution of air bubbles in size), as well as sensory and visual experience. Examples of such preferred embodiments of the invention are preparations in the form of a mousse.

Polysorbate

In the proposed invention the preparations preferably you can also enter Polysorbate. In accordance with the invention, the preferred Polysorbate are, for example, the following products (CAS means the registration number in Chemical Abstacts):

- polyoxyethylene(20)sorbitanoleat (Tween 20, CAS-Nr. 9005-64-5),

- polyoxyethylene(4)sorbitanoleat (Tween 21, CAS-Nr. 9005-64-5),

- polyoxyethylene(4)servicemaster (Tween 61, CAS-Nr. 9005-67-8),

- polyoxyethylene(20)sorbitanoleat (Tween 65, CAS-Nr. 9005-71-4),

- polyoxyethylene(20)servicemanual (Tween 80, CAS-Nr. 9005-65-6),

- polyoxyethylene(5)servicemanual (Tween 81, CAS-Nr. 9005-65-5),

- polyoxyethylene(20)sorbitan the oleate (Tween 85, CAS-Nr. 9005-70-3).

According to the invention particularly preferred Polysorbate are:

- polyoxyethylene(20)servicemanagement (Tween 40, CAS-Nr. 9005-66-7) and

- polyoxyethylene(20)servicemaster (Tween 60, CAS-Nr. 9005-67-8).

Polysorbate used individually or as a mixture of several Polysorbate preferably in a concentration of from 0.1 to 5 wt%. first of all, from 1.5 to 2.5% of the mass. in terms of the total weight of the preparation.

Conditioning tools

The proposed invention in cosmetic preparations in addition to the above polyurethanes PU and at least one cosmetically acceptable bases, preferably water, preferably also contain at least one conditioning agent. As a means of conditioning the proposed invention in cosmetic preparations preferably contain additives selected from the group listed in the text of the international application WO 2006/106140 from line 24 on p.34 on line 10 on p.37 inclusive. The specified text in full should be considered an appropriate reference. Other preferred conditioning means are hydrogenated polyisobutene-Lena, the first commercially available product Luvitol®Lite.

Means of modifying the rheology

Rheological properties proposed in the invention of drugs in General monostearate at the required level through used according to the invention the polyurethanes PU. The use of other means of modifying the rheology is not required.

However, in the proposed invention the drugs, obviously, you can also use other thickeners. Thickeners suitable for use in gels, shampoos and tools for hair care, please see pages 235-236 "Kosmetik and Hygiene von Kopf bis FuR", W. Umbach (editor), 3 edition, Wiley-VCH, 2004 (the text in full should be considered an appropriate reference). Other thickeners suitable for use in the proposed invention in cosmetic preparations, see, for example, in international application WO 2006/106140 from line 12 on pp.37 on line 8 ñ.38 inclusive. The specified text in full should be considered an appropriate reference.

In a preferred embodiment of the invention proposed in the invention of drugs in addition to the polyurethanes PU does not contain any other means of modifying rheology.

Another object of the present invention are cosmetic preparations, which in addition to the polyurethanes PU also contain other means of modifying the rheology. One of the embodiments of the invention relates to cosmetic preparations which contain the above-mentioned polyurethanes PU and polyacrylate thickeners, primarily of hydrophobic modificirowan the e polyacrylate thickeners. To the main positive variant implementation of the invention relates to cosmetic preparations containing at least one polyurethane PU and at least one polyacrylate thickener named according to the nomenclature INCl cross-linked polymer of acrylates/C 10-30 alkylacrylate (e.g., Carbopol®Ultrez 21).

Cosmetic preparations containing at least one polyurethane PU and at least one crosslinked polymer of acrylic ATA/S 10-30 alkylacrylate are, for example, gels, which at the same viscosity are characterized by improved sensor technology.

The combination of polyurethanes PU with hydrophobically modified polyacrylates poses synergistic effects of thickening. The combination of polyurethanes PU with polyacrylates, primarily with hydrophobic modified polyacrylates, when the limited-use number provides equal or stronger thickening effect compared using one-liability thickeners. The corresponding formulations are characterized by a light sensor and a great capacity for distribution, for example, on the skin.

Another object of the present invention is a method for improving the ability of cosmetic products, especially cosmetic preparations in the form of emulsions, for distribution on the skin, otlichalis the same time, what to cosmetic preparation add at least one polyurethane PU, the amount of which, calculated on the total weight of the preparation is from 0.1 to 10% of the mass.

Preservatives

Drugs with high water content first of all need reliable protection from infection by microorganisms. The proposed invention in cosmetic preparations in a preferred embodiment, the invention contain preservatives.

Preservatives suitable for use in the proposed invention in cosmetic compositions, described, for example, in international application WO 2006/106140 with a line 10 from 38 to line 18 on p.39 inclusive. The specified text in full should be considered an appropriate reference.

Komleksoobrazovateli

As the feedstock for the production of many cosmetic products are mainly in steel appliances, end cosmetic products may contain traces of iron (iron ions). To prevent the deterioration of cosmetic products because of a possible interaction of these impurities with dyes and components of perfume oils in accordance with the preferred embodiment of the invention in cosmetic preparations add kompleksoobrazovateli, such as salts of ethylenediaminetetraacetic acid, nitrilo ioxynil acid, iminodiethanol acid or phosphates.

Protection from ultraviolet radiation

With the purpose of stabilizing ingredients proposed in the invention of drugs, such as dyes and perfume oils, which can prevent their change under the action of ultraviolet light, in the products, you can type UV filters, such as benzophenone derivatives. UV filters are suitable for use in the proposed invention in cosmetic preparations, see, for example, in international application WO 2006/106140 with line 39 on p.39 on line 10 on p.41 inclusive. The specified text in full should be considered an appropriate reference. Other suitable UV filters below when considering cosmetic UV light-protective preparations.

Buffers

In a preferred embodiment of the invention, the cosmetic preparations contain buffers. The buffers provide the stability of the pH of the proposed invention in cosmetic preparations. The predominant use shall be subject citrate, lactate, and phosphate buffers.

Girotropnye soljubilizatory

In a preferred embodiment of the invention, the cosmetic preparations contain girotropnye soljubilizatory. Girotropnye soljubilizatory used to preserve the transparency of the races the thieves oils or perfume oils, designed for hair care, including their transparency on cold. The most common hydrotropism soljubilizatorami are ethoxylated nonionic surfactants, for example, gidrirovannoe and ethoxylated castor oil. Used according to the invention, the polyurethanes PU themselves may have the effect hydrotropic of solubilization.

Means for inhibiting bacteria

In a preferred variant of the invention, the cosmetic preparations contain tools, inhibiting bacterial growth. Generally, such tools include any suitable preservatives, which have a specific action against graphology-positive bacteria, for example, triclosan (2,4,4'-trichloro-2'-hydroxide-phenyl ether), chlorhexidine [1,1'-hexamethylenebis[5-(4-chlorophenyl)-iguanid], as well as product TTC (3,4,4'-trichlorocarbanilide). Suitable means for inhibiting bacteria in principle are also Quaternary ammonium compounds that are preferably used in disinfectants, Soaps and lotions. Antimicrobial properties are also many fragrances. In addition, a pronounced antimicrobial action have many essential oils and contains ingredients such as clove oil (even the l), mint oil (menthol) or thyme oil (thymol). The content of substances with antibacterial action proposed in the invention of the drugs typically is in the approximate range from 0.1 to 0.3% of the mass. in terms of preparation.

Dispersers

If in the proposed invention the drugs must be atomized sparingly soluble or insoluble ingredients, such as active substances against dandruff or silicone oil, and a balanced state of these ingredients should be kept for a long time, you should use dispersing agents and thickeners, such as silicates of magnesium/aluminum, bentonites, derivatives of saturated carboxylic acids, polyvinylpyrrolidone or hydrocolloids, in particular, xanthan resin or carbomer.

According to the invention, the total content of the above ingredients is not more than 2% of the mass. preferably not more than 1.5% of the mass. especially preferably not more than 1% of the mass. in terms of the total weight of the preparation.

In accordance with a preferred embodiment of the invention proposed in the invention of drugs, such as gels, shampoos and hair care products contain ethoxylated oils selected from the group comprising ethoxylated esters on the basis of glycerol and fatty acids, n is IDE just preferably PEG-10 olive oil glycerides, PEG-11 glycerides of avocado oil, PEG-11 glycerides cocoa butter, PEG-13 sunflower oil glycerides, PEG-15 glycerylmonostearate, PEG-9 glycerides of fatty acids of coconut oil, PEG-54 gidrirovannoe castor oil, PEG-7 gidrirovannoe castor oil, PEG-60 gidrirovannoe castor oil, ethoxylated jojoba oil (PEG-26 fatty acid oils jojoba, PEG-26 alcohol jojoba oil), glycereth-5 Cocoate, PEG-9 glycerides of fatty acids of coconut oil, PEG-7 literallayout, PEG-45 palm kernel glycerides oil, PEG-35 castor oil, olive oil PEG-7 esters, PEG-6 glycerides of Caprylic/capric acids, PEG-10 olive oil glycerides, PEG-13 sunflower oil glycerides, PEG-7 gidrirovannoe castor oil, glycerides hydrogenated palm kernel oil PEG-6 esters, PEG-20 corn oil glycerides, PEG-18 gLite-relaled Cocoate, PEG-40 gidrirovannoe castor oil, PEG-40 castor oil, PEG-60 gidrirovannoe castor oil, PEG-60 corn oil glycerides, PEG-54 gidrirovannoe castor oil, PEG-45 palm kernel glycerides oil, PEG-80 literallayout, PEG-60 almond oil glycerides, PEG-60 glycerides evening primrose oil, PEG-200 hydrogenated literalmath and PEG-90 glycerylmonostearate.

To the preferred ethoxylated oils include PEG-7 gLite-ricochet, PEG-9 cocoglycerides, the EG-40 gidrirovannoe castor oil and PEG-200 hydrogenated literalmath.

Ethoxylated esters on the basis of glycerol and fatty acids are used in detergent formulations with different goals. If the degree of amoxilonline of such substances is from about 30 to 50, they are used as hydrotropic of solubilization to dissolve non-polar substances, such as perfume oils. Esters with a high degree of amoxilonline used as thickeners.

Active ingredients

In accordance with a preferred embodiment of the invention proposed in the invention, the preparations contain cosmetically and/or dermatologically active ingredients. Preferred active ingredients are listed, for example, in international application WO 2006/106140 from line 24 on p.44 on line 39 to 49 inclusive. The specified text in full should be considered an appropriate reference.

To another variant embodiment of the invention are cosmetic products that contain at least one of the above polyurethane PU and 0.1 to 20 wt%. preferably from 0.5 to 15 wt. -%, more preferably from 5 to 12% of the mass. carbamide. In the case of the simultaneous presence of polyurethane PU in cosmetic preparations without loss of stability and establishment of the necessary viscosity can be introduced quite a substantial amount of carb the foreign Ministry.

Wax to impart a pearlescent Shine

In a preferred embodiment of the invention proposed in the invention, the preparations contain wax to impart a pearlescent Shine. Suitable waxes of this type that can be used in the proposed invention in cosmetic preparations, see, for example, in international application WO 2006/106140 on page 50 from line 1 to line 16. The specified text in full should be considered an appropriate reference.

In addition, the proposed in the invention, the preparations may contain substances with the crystal lattice and/or other substances designed to create those or other (e.g., color) effects.

Emulsifiers

In accordance with a preferred embodiment of the invention proposed in the invention, the cosmetic preparations are in the form of emulsions, preferably in the form of emulsions of the type oil-in-water". Such emulsions receive known methods. Emulsifiers suitable for use in the proposed invention the emulsions described, for example, in international application WO 2006/106140 from line 18 on p.50 on line 4 on p.53 inclusive. The specified text in full should be considered an appropriate reference.

Perfume oils

In accordance with a preferred embodiment of the image is etenia proposed in the invention, the cosmetic preparations contain perfume oil. Suitable perfume oils are listed, for example, in international application WO 2006/106140 with line 10 on p.53 on line 3 p.54 inclusive. The specified text in full should be considered an appropriate reference.

Pigments

In accordance with a preferred embodiment of the invention proposed in the invention, the cosmetic preparations also contain pigments. In most cases, the pigments are in the drug in a dissolved state, and their number may vary from 0.05 to 90% of the mass. particularly preferably from 1 to 15% of the mass. In one of the embodiments of the invention, especially in the case of drugs in the form of decorative cosmetics such as eyeshadow, pigment content in the product can reach 90% of the mass.

The preferred particle size of the pigment is from 0.01 to 200 μm, especially from 0.02 to 150 μm, particularly preferably from 0.05 to 100 μm.

Pigments suitable for use in the proposed in the invention compositions, described, for example, in international application WO 2006/106140 from line 5 on p.54 on line 19 p.55 inclusive. The specified text in full should be considered an appropriate reference.

Nanoparticles

In accordance with a preferred embodiment of the invention proposed in the invention of space is political preparations also contain pigments in the form of a water-insoluble nanoparticles, that is, particles with sizes from 1 to 200 nm, preferably from 5 to 100 nm. Preferred are nanoparticles of metal oxides, especially zinc oxide, titanium dioxide and/or silicon dioxide.

Polymers

In accordance with a preferred embodiment of the invention used in addition to polyurethanes according to the invention proposed in the invention, the cosmetic preparations contain other polymers. Preferred other polymers are water-soluble, respectively, water dispersible polymers, especially preferred are water-soluble polymers.

Other suitable polymers for the proposed in the invention of the drugs listed, for example, in international application WO 2006/106140 with line 21 on p.55 on line 2 in p.63 inclusive. The specified text in full should be considered an appropriate reference.

Cosmetic and/or dermatological light stabilizers

Under cosmetic, respectively dermatological light stabilizers in accordance with the present invention involve cosmetic, respectively dermatological preparations, which contain at least one UV filter substance, preferably several UV filter substances.

UV-filtering substances known in the art and means substances and and medications, added to cosmetic or dermatological tools with the aim of filtering UV rays to protect the skin from certain harmful effects of these rays. In a more narrow sense it is also about the compounds that absorb light with wavelengths that are in the UV range. Depending on the spectral range of UV absorption distinguish between UV-A, UV-b and UV-filters. To meet the spectral and prescription-technical requirements UV filters are generally used in the form of appropriate combinations.

UV filters are also called mainly used for these purposes, pigments and micropigment, preferably titanium dioxide and/or zinc oxide (see above).

The proposed invention in cosmetic preparations, obviously, may be suitable for use in cosmetic and dermatological purposes. Therefore, the term "cosmetic or dermatological light" can be used to refer to compositions that simultaneously satisfy both cosmetic and dermatological requirements.

The preferred implementation of the present invention relates to light protection compositions factor Svetozara comprising at least 4, especially to such a cosmetic or dermatological sitostanol the gridlock which contain at least one UV filter substance.

Used according to the invention the cosmetic and/or dermatological light protection preparations intended for cosmetic and/or dermatological protection from exposure to light, and also for treatment of skin and/or hair and care for them and as a cosmetic product in decorative cosmetics.

To cosmetic and/or dermatological light protection preparations according to the present invention include, for example, sunscreens, lotions, funds in the form of milk, oils, balms, gels, products for skin care lips and lipsticks, protective creams and pencils, moisturizing creams, lotions and emulsions, creams for face, body and hands, therapeutic agents and conditioners for hair, clips hair, styling gels, hair sprays, hair, ball deodorants or creams against wrinkles at the corners of his eyes, preparations for sun protection in tropical conditions, and preparations for the care of the skin after sunburn. All of the above light-protective preparations contain at least one UV filter substance and possess a factor Svetozara comprising preferably at least 4.

Function UV light protection filters perform as inorganic pigments, for example titanium dioxide or zinc oxide, and organic is soedineniya, in most cases, aromatic substances with a characteristic system of π-electrons.

Sunscreen can be in different forms. Particularly prevalent water-resistant products, which is contained in the filter material after contact with the skin and/or hair washed with water immediately. The flushing of the filter substances prevent water present in the light stabilizers other substances.

In one of the embodiments the present invention relates to cosmetic light protection preparations selected from the group including cosmetic and dermatological light stabilizers containing used according to the invention the polyurethanes. In accordance with the present invention under cosmetic or dermatological light stabilizers mean cosmetic or dermatological preparaty, which in addition to used polyurethanes according to the invention contain at least one UV filter substance, preferably several UV filter substances. Factor Svetozara used according to the present invention is a cosmetic or dermatological light stabilizers, determined as described below COLIPA method, is preferably at least 4.

Sunscreen lotion and sunscreen predpochtitel what about the perform in the form of emulsions of the type oil-in-water" or "water in oil". Properties of cosmetic products very much depend on the type of emulsion. The emulsion of the type oil-in-water" easily distributed on the surface of the skin, in most cases, quickly penetrate her and almost always easily washed off with her water. Emulsion type water in oil rubbed harder into the skin, they are stronger sirivat and thereby determine its stickiness, but better protects the skin from dehydration. Emulsion type water in oil" in most cases possess resistance. Crucial to the emulsions of the type oil-in-water" has the choice of basis and adequate light protection substances, and also depending on the required degree of water resistance selection optionally used auxiliary substances (e.g., polymers). The basic requirements for liquid and creamy emulsions of the type oil-in-water in the composition similar to the corresponding requirements for conventional emulsions for skin care. Sunscreen lotion should provide a fairly complete supply dehydrated skin fat to protect it from exposure to sun, water and wind. However, the skin should not be sticky, because in such a case, when heated and in contact with sand can be particularly unpleasant sensations.

The basis of sitosterolemia typically contains at least one mA is driving oil phase. However, there are also drugs only water-based. Thus, suitable drugs are appropriate oil emulsion of the type oil-in-water, emulsion type water in oil, creams, pastes, protective lipsticks or not containing fats gels.

As emulsions, in particular, suitable also microemulsion and micro-emulsions of the type oil-in-water or emulsion type oil/water/oil containing buried them particles of titanium dioxide coated, and such emulsions can be obtained, for example, in accordance with PETE-technology (technology for the treatment phases) according to the German patent application DE-A-19726121.

Conventional cosmetic excipients that can be used as additives are, for example, (co), emulsifiers, fats and waxes, stabilizers, other thickeners, biogenic substances act, film formers, fragrances, dyes, means to impart a pearlescent luster, preservatives, pigments, electrolytes (e.g. magnesium sulfate) and regulators of pH.

As stabilizers it is possible to use metal salts of fatty acids such as magnesium stearate, aluminum stearate and/or zinc stearate.

Biogenic active vasectamy mean, for example, plant extracts, protein hydrolysates and complexes of vitamins is s.

As film-forming agents are suitable, for example, hydrocolloids, such as chitosan, microcrystalline chitosan or Quaternary chitosan, polyvinylpyrrolidone, copolymers of vinylpyrrolidone with vinyl acetate, polymers of acrylic acid, Quaternary cellulose derivatives and similar compounds.

Factor Svetozara and COLIPA method

Factor Svetozara (sun protection factor LSF) in European countries are determined according to the COLIPA standard European Association of cosmetic, hygiene and perfumery products. Factor Svetozara determines the protective ability of the sunscreen cosmetic products from UV rays C. Ultraviolet rays of the spectrum are the main cause of sunburn. In addition, they are characterized by IMMUNOSUPRESSIVE exposure and cause damage to cells that chronic UV stress contributes to skin cancer (basal cell carcinoma, spinocellular cancer). For optimal sun protection ability of cosmetic products use different UV filters, respectively UV-filter systems and combinations. This determines the minimum dose that causes redness of the skin (minimal erythema dose MED), i.e. the dose of the ultraviolet radiation spectrum, causing a visually detectable is redness of the skin, and according to the formula:

calculate the corresponding factor Svetozara (LSF).

Testing begins with determining individual sensitivity of subjects to ultraviolet light through the exposure of unprotected skin area on their back. When this radiation sources are simulated sunlight, in most cases, equipped with xenon lamps emitting light, which has a similar sunlight spectral characteristics, however, has a higher intensity, thus reducing the duration of the experiment. After about 20 hours after made with different irradiation intensity of the six areas of the skin visually estimate the reddening of the skin (MEDu).

With the aim of directly determining factor Svetozara on other areas of the skin of the subjects put under investigation sunscreen preparations. The results of the exposure of these areas compared with the state of the neighboring untreated (control) areas of the skin. The irradiation intensity set depending on skin sensitivity and the expected factor Svetozara. After about 20 hours visually determine MEDuand MEDg. Summary of factor Svetozara corresponds to the average increase an individual who is a high amount of time before the onset of redness, achieved through the use of appropriate lighting of the drug.

Method COLIPA known in the art, and since 1997 it is widely used in European countries to determine the factor Svetozara sunscreen products (factor of protection against UVB rays). Methodology sootvetstvujushij tests are standardized and normalized, that is precisely defined as the radiation spectrum used for testing solar simulator radiation and its power output. In addition, just set the number to be causing drugs and methods of their application. The test method does not depend on skin type and age of the subjects. Thanks to precise the conditions of the tests carried out according to the COLIPA method required an average characteristics of the sunscreen cosmetic products can be obtained on the basis of test results no more than ten subjects. Method COLIPA allows high reproducibility to obtain reliable results.

UV-filtering substances

In one of the embodiments of the invention proposed in the invention of the drugs used in addition to polyurethanes according to the invention contain oil-soluble and/or water-soluble UVA and/or UVB filters.

Such light protection preparations preferably contain substances absorbing the UV radiation in the UVB region of the spectrum, as well as substances that absorb ultraviolet radiation in the UVA region of the spectrum, and the total number of the specified filter substances is, for example, from 0.1 to 50 wt. -%, preferably from 0.5 to 30 wt. -%, first of all, from 1 to 15% of the mass. in terms of the total weight of the preparations, which allows us to offer cosmetic products, protecting the skin in the whole spectral range of ultraviolet radiation.

A large part of the light stabilizers contained in intended for protection of the human epidermis cosmetic or dermatological preparations, consists of compounds that absorb ultraviolet rays in the UVB region of the spectrum. For example, the share be used according to the invention UFA-absorbers is from 10 to 90 wt. -%, preferably from 20 to 50 wt%. in terms of cumulative number of UVB - and UVA-absorbing substances.

In accordance with another embodiment of the invention first of all create the sunscreen formulations that contain polyurethanes with UVA-balance set, as described in European patent EP 1291640 A1 or as established by the German industrial standard DIN 67502 (quality standard for protection of the skin from aging due to exposure to light). The text of these documents in full should be considered with the relevant link.

UVB-filter substances can be oil-soluble, water-soluble or pigmented. Preferred UVB-filter substances are, for example, are:

derivative benzimidazolecarboxylate, such as 2-phenylbenzimidazole-5-acid and its salt,

derivative benzotriazole, such as 2,2'-Methylenebis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-TETRAMETHYLBUTYL)phenol (Tinosorb®M)

- derivatives of 4-aminobenzoic acid, preferably a complex 2-ethylhexyloxy ester of 4-(dimethylamino)benzoic acid, complex amyl ester of 4-(dimethylamino)benzoic acid,

- esters of benzylmalonate acid, preferably di(2-ethylhexyloxy) ether 4-methoxybenzeneboronic acid,

- esters of cinnamic acid, preferably 2-ethylhexyl wet ether 4-methoxycatechol acid, isopentylamine ether 4-methoxycatechol acid,

derivatives of benzophenone, preferably 2-hydroxy-4-methoxy-benzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone and 2,2'-dihydroxy-4-methoxybenzophenone,

derivative metaliterature, preferably 4 methylbenzyl-discomfor and benzylideneamino,

- triazine derivatives, preferably a complex of Tris(2-ethylhexyloxy ether) 4,4',4"-(1,3,5-the triazine-2,4,6-treeline)Tris-benzoic acid [name according to nomenclature INCl diethyl-the EC-cellularization, UVA-Sorb®NEUVE (firm 3V Sigma)] and 2,4,6-Tris[aniline(p-Carbo-2'-ethyl-1'-hexyloxy)]-1,3,5-triazine [name according to nomenclature INCl ochiltree, Uvinul®T 150 (BASF)].

Preferred to be water-soluble UVB-filter substances are, for example: sulfonylurea derivatives of 3-benzylideneacetone, such as 4-(2-oxo-3-barelydigital)benzosulfimide, 2-methyl-5-(2-oxo-3-barelydigital)acid and their salts.

Preferred to be water-soluble UVA-filter substances are, for example:

derivatives of 1,4-phenyleneterephthalamide, such as 3,3'-(1,4-phenylendiamine)-bis(7,7-dimethyl-2-oxobicyclo-[2.2.1]-heptane-1-methanesulfonate and its salt,

derivatives of 1,3,5-triazine, such as 2,4-bis{[(2-ethylhexyloxy)-2-hydroxy)phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (for example, product Tinosorb®'s company Ciba),

derivatives dibenzoylmethane, preferably 4 isopropyl-benzoylmethyl and 4-(Traag-butyl)-4'-methoxydibenzoylmethane,

derivatives benzoxazole, for example, 2,4-bis[4-[5-(1,1-dimethyl-propyl)benzoxazol-2-yl]phenylamino]-6-[(2-ethylhexyl)imino]-1,3,5-triazine (CAS Nr. 288254-1-6-0, Uvasorb®K2A firm 3V Sigma),

- hydroxybenzophenone, for example, a complex hexyl ester of 2-(4'-diethylamino-2'-hydroxybenzoyl)benzoic acid, called the th also aminobenzophenone (product Uvinul ®A Plus BASF).

In addition, the proposed invention medications if necessary, preferably can be provided to other UVA and/or UVB-filter-forming substances, for example, certain derivatives of salicylic acid such as 4-isopropylbenzylamine, 2-ethylhexylacrylate, octisalate or geomantically. The total number of derivatives of salicylic acid in the proposed invention in cosmetic or dermatological preparations may preferably be in the range from 0.1 to 15.0 wt%. preferably from 0.3 to 10.0 wt%, calculated on the total weight of the preparations. Other light protection filter to be the preferred use according to the invention is ethylhexyl-2-cyano-3,3-diphenylacetate (octocrylene, for example, a commercially available product Uvinul®N 539 BASF).

The following table shows some light protection filter substances suitable for use in the proposed invention the drugs.

No.SubstanceCAS-Nr. (for acid)
14-Aminobenzoic acid150-13-0
23-(4'-Tr is methylammonium)benzylideneamino-2-he-methyl-sulfate 52793-97-2
33,3,5-Trimethylcyclohexylamine (homosalate)118-56-9
42-Hydroxy-4-methoxybenzophenone (oxybenzone)131-57-7
52-Phenylbenzimidazol-5-acid and the corresponding salts of potassium, sodium and triethanolamine27503-81-7
63,3'-(1,4-Phenylendiamine)bis(7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonate) and its salts90457-82-2
7Polyethoxyethanol ether 4-bis(polyatomic)aminobenzoic acid113010-52-9

td align="left"> Complex 2-isoamyl ether 4-methoxycatechol acidtd align="left"> 29
No.SubstanceCAS-Nr. (for acid)
8Complex 2-ethylhexyloxy ether 4-dimethylaminobenzoyl acid21245-02-3
9Complex 2-ethylhexyloxy ester of salicylic acid118-60-5
1071617-10-2
11Complex 2-ethylhexyloxy ether 4-methoxycatechol acid5466-77-3
122-Hydroxy-4-methoxybenzophenone-5-acid (sulisobenzone and its sodium salt4065-45-6
133-(4'-Sulfonanilide)Bornand-2-he and its salts58030-58-6
143-benzylideneamino-2-on16087-24-8
151-(4'-Isopropylphenyl)-3-phenyl propane-1,3-dione63260-25-9
164 Isopropylbenzylamine94134-93-7
173-Imidazol-4-Lacrimosa acid and its complex ethyl ester104-98-3
18Complex ethyl ester of 2-cyano-3,3-diphenylamino-howl acid5232-99-5
19Complex 2'-ethylhexyloxy ester 2-cyano-3,3-diphenylamino the second acid 6197-30^*
20Menthyl-o-aminobenzoate or 5-methyl-2-(1-methylethyl)-2-aminobenzoate134-09-8
21Glyceryl-p-aminobenzoate or 1-gliterry ester of 4-aminobenzoic acid136-44-7
222,2'-Dihydroxy-4-methoxybenzophenone (dioxybenzone)131-53-3
232-Hydroxy-4-methoxy-4-methylbenzophenone (Maxton)1641-17-4
24Triethanolaminato2174-16-5
25Dimethoxyphenylacetic acid or sodium salt of 3,4-dimethoxyphenylacetic acid4732-70-1
263-(4'-Sulfonanilide)Bornand-2-he and its salts56039-58-8
274-tert-butyl-4'-methoxydibenzoylmethane70356-09-1
282,2',4,4'-Tetrahydroxybenzophenone131-55-5
2,2'-Methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-TETRAMETHYLBUTYL)phenol]103597-45-1
302,2'-(1,4-Phenylene)bis-1H-benzimidazole-4,6-disulfo-acid, sodium salt180898-37-7
312,4-Bis[4-(2-ethylhexyloxy)-2-hydroxy]phenyl-6-(4-methoxyphenyl)(1,3,5)-triazine187393-00-6
323-(4-Methylbenzylidene)camphor36861^*7-9
33Polyethoxyethanol ether 4-bis(polyatomic)para-aminobenzoic acid113010-52-9
342,4-Dihydroxybenzophenone131-56-6
352,2'-Dihydroxy-4,4'-dimethoxybenzophenone-5,5'-disodium sulfonate3121-60-6
36Complex hexyl ester of 2-[4-(diethylamino)-2-hydroxyethylbenzene acid]302776-68-7

No.SubstanceCAS-Nr. for acid)
372-(2H-Benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl]-propyl]phenol155633-54-8
381,1-[(2,2'-DIMETHYLPROPANE)carbonyl]-4,4-diphenyl-1,3-butadiene363602-15-7

In addition, according to the invention can also be used the polymer or United with polymers of media, such as product Parsol®SLX.

The light stabilizers suitable for use in the proposed invention the drugs are also compounds listed in paragraphs [0036] to [0053] the description of European patent application EP-A 1084696 that in full should be considered an appropriate reference. Suitable for use in the proposed invention the drugs are any UV protective filters specified in Appendix 7, §3b German regulations on cosmetics "UV filters cosmetic products".

In sun care products find wide application metal oxides, such as titanium dioxide or zinc oxide. The effect of such oxides is mainly based on the reflection, scattering and absorption of harmful ultraviolet radiation and essentially depends on the size of the and of the relevant primary particles. In a particularly preferred embodiment of the invention proposed in the invention is a cosmetic or dermatological preparations contain inorganic pigments based on metal oxides and/or other soluble or water-insoluble compounds of metals selected from the group comprising the oxides of zinc (ZnO), iron oxides (for example, Fe2About3), Zirconia (ZrO2), silicon oxides (SiO2), oxides of manganese (for example Mno), aluminum oxide (Al2O3), oxides of cerium (for example, CE2O3), mixed oxides of the corresponding metals, and mixtures of these oxides, and alloys, oxides of alien metals, respectively, metal oxides, provided with a coating of other metal oxides. It is especially preferably is about pigments based on ZnO and/or Tio2.

Thus, particularly preferred embodiments of the invention relates to cosmetic or dermatological light protection preparations that contain used according to the invention the polyurethanes and zinc oxide and/or titanium dioxide as inorganic UV protective filter.

In accordance with another embodiment of the invention the viscosity of the water-containing proposed in the invention containing preparations used according to izobreteny the polyurethane and at least one light, primarily zinc oxide or titanium dioxide, compared with products that contain only light or only used in accordance with the invention, the polyurethanes, can be enhanced by the presence in the proposed invention the preparations of these polyurethanes. The sequence in which add polyurethanes and light stabilizers, is not significant.

Inorganic pigments can be provided with a coating form. Such coating may be, for example, a thin hydrophobic layer applied to the pigments known method described, for example, in German patent application DE-A-3314742.

Particularly preferred cosmetic light protection preparations used in addition to polyurethanes according to the invention and a cosmetically acceptable bases contain UV light shielding means on the basis of zinc oxide, commercially available under the name Z-Cote®Z-Cote®HP1 or Z-Cote®MAX.

Particularly preferred cosmetic light protection preparations in addition to used according to the invention the polyurethanes PU contain UV light shielding means on the basis of titanium dioxide, commercially available under the name T-Lite®T-Lite™SF, T-Lite™SF-S or T-Lite™MAX.

The list above UV protective filters that can be used in the proposed who's in the invention of the drugs, is not final.

In accordance with one variant of cosmetic preparations contain the above polyurethane PU and at least one water-soluble UV filter.

In accordance with another variant of cosmetic preparations contain the above polyurethane PU and at least one ionic UV filter.

So, for example, can be the ideal way to prepare stable formulations containing 2-phenylbenzimidazol-5-acid (Eusolex®232) in the most high Concentratio, reaching 8% of the mass. what previously was not possible. In addition, unlike other thickening systems in the presence used according to the invention of the above polyurethane polyurethane PU can also produce stable preparations containing a combination of different UV filters, with a pleasant feeling when Petrasiunai processed to their skin.

Preparations for decorative cosmetics

The present invention relates also to those who are preferably in liquid or pasty form cosmetic preparations intended for application on the skin, polylith membranes and mucous membranes, and primarily on the keratin materials such as hair, eyelashes and eyebrows, first of all for making the last a certain shape, decoration, painting and improvements in enego view as well as for skin care and skin appendages. These drugs primarily find application, for example, to shape and colouring of eyelashes and hair, and in this case they are called mascara and eyebrow.

Proposed in the invention of drugs in case of proper regulation of their composition and pigmentation, in principle, can also be used as make-up, corrective cosmetic products, concealers, cosmetic, eyeshadow, contour pencils for the eye contour pencils, lip gloss, blush, lipstick, lip gloss, sunscreen, sunscreen preparations, temporary tattoo, create color effects, protect from the sun of surfers, and so on.

Thus, a preferred variant implementation of the present invention include drugs used as decorative cosmetics. Under the decorative cosmetics preferably involve drugs that are used for cosmetic treatment of the skin and which contain at least one decorative component, such as a dye, pigment or pearlescent pigment. These drugs are also called tonal creams or makeup. In the field of cosmetics for coloring certain cosmetic products or liable is the first cosmetic treatment of the object (skin, hair or lips) allowed both soluble coloring tools (called in accordance with the present invention also dyes)and insoluble coloring tools (called in accordance with the present invention (in color) pigments). Any decorative tools for body care products contain more or less significant amounts of dyes, pigments and/or pearlescent pigments, since the primary purpose of such funds is discoloration of the skin, the skin around the eyes and lips and/or nails. Along with this, these products usually contain additional ingredients that have caring or protecting the skin effect. Used for makeup cosmetic preparations depending on the characteristics and individuality of human beings in General should be different from each other, so that with their help it was possible to emphasize the attractiveness of a person and to disguise the possible flaws of his skin. The process of applying cosmetics is usually carried out in several stages. First, put the liquid primer layer (concealer or makeup for the face), which allows to adjust the color of the skin and disguise its irregularity (for example, defects or circles under the eyes). The facial skin needs to give a natural h is a simple color and a youthful appearance. More significant bumps or redness you can additionally use coloring cosmetic pencil or liquid corrective cosmetic preparation. After that with the purpose of matting the skin usually cause loose or compact powder. Then the cheeks can be toned blush and skin around the eyes to expose the cosmetic treatment of eye shadow pencil to create contour on the inner eyelid (kaalam), contour grandson and/or ink for eyelashes and eyebrows. Used for make-up preparations preferably may also contain silicone oil, respectively silicone derivatives, which contribute to an extremely uniform distribution of cosmetic products on the surface of the skin, and, in addition, give it a lean smooth Shine and sensation of velvety when Petrasiunai.

In one of the embodiments of the invention proposed in the invention of cosmetic products are emulsions water in oil". In a preferred variant of the invention, the cosmetic preparations are emulsions of the type oil-in-water".

Proposed in the invention of drugs primarily suitable for masking imperfections and/or circles under the eyes and wrinkles, as well as to give the skin a uniform, estestvenno pure color and young appearance. Achieved according to the invention the effect is unexpectedly long. Proposed in the invention of drugs applied to the skin in the usual cosmetics sufficient quantities. They may have a regular structure and can serve as preparations for skin care and decorative cosmetic preparations.

The pigments used in the present invention in decorative cosmetic preparations, can be both inorganic and organic. Preferred pigments described in paragraphs [0018] to [0026] the description of the German patent DE 102006028549 A1, the text of which in full should be considered an appropriate reference.

In addition, the proposed invention in cosmetic preparations preferably contain one or more dyes. The dyes can be both synthetic and natural. Proposed in the invention, the cosmetic preparations can preferably also contain fillers, which, for example, further improve the sensory and cosmetic properties of drugs, and, for example, contribute to the emergence of the feeling of velvety or silky when Petrasiunai to the skin or reinforce this feeling.

Preferred fillers in accordance with the present invention include starch, carried the major starch (for example, such as tapioca starch, dichromatic, aluminum, respectively, sodium starch, octenylsuccinate and so on), pigments, not related to UV-filters and not having a coloring effect (such as boron nitride, etc.) and/or product Aerosile®(CAS-Nr. 7631-86-9), Euroline, polymethylsilsesquioxane, polymetylmetacrylate, stitched polymetylmetacrylate, nylon, talc, talcum powder, the particles of which are covered with, for example, Dimethicone and trimethylchlorosilane, as well as mica and silicon dioxide.

If the proposed in the invention, the preparations are emulsions of the type water-in-silicone oil", they preferably can contain one or several other (silicone) emulsifiers, preferably emulsifiers with an indicator hydrophilic-lipophilic balance of 8 or less.

Preferred silicone emulsifiers are given in paragraphs [0032] to [0037] the description of the German patent DE 102006028549 A1, the text of which in full should be considered an appropriate reference.

In addition, the proposed invention in cosmetic preparations, especially if they are in the form of emulsions of the type water-in-silicone oil, preferably can contain one or more surface-active polyethers. Preferred surface-active polyethers lead is received in the paragraph [0038] the description of the German patent DE 102006028549 A1, the text is in full should be considered an appropriate reference. The total number of surface-active polyethers in the finished cosmetic preparations is preferably from 0.1 to 30% wt. preferably from 0.25 to 5.0% of the mass. and first of all from 0.75 to 3.5% of the mass. accordingly, calculated on the total weight of the preparation.

Proposed in the invention, the preparations can be in the form of emulsions water in oil". According to the invention in this case it is preferable to use the emulsifiers listed in paragraph [0041] the description of the German patent DE 102006028549 A1.

In accordance with a particularly preferred variant of the invention, the oil phase contains a cyclic and/or linear silicone oils are used as the sole oil component.

In addition, the oil phase may be present dial Kyl carbonates, for example, preferably disabilitant produced, for example, by the company Cognis under the trade name Cetiol®CC. Along with this, the oil phase may contain triglycerides, such as Caprylic/capric triglycerides, simple dialkyl ethers, such as dicaprylyl ether, natural oils such as jojoba oil, avocado oil, sesame oil, almond oil, soybean oil or apricot oil, as well as linear or branched hydrocarbons the odes. The oil phase is proposed in the invention of drugs preferably may also contain waxy components, especially the wax, the melting point of which is in the range from 30 to 45°C., particularly preferably in the range between 30 and 40°C. the Preferred wax referred to in paragraph [0049] the description of the German patent DE 102006028549 A1, the text of which is in full should be considered an appropriate reference.

In addition, the proposed invention the preparations for decorative cosmetics preferably contain preservatives, komleksoobrazovateli, antioxidants and active ingredients specified in paragraph [0063] the description of the German patent DE 102006028549 A1.

In the aqueous phase proposed in the invention preparations for decorative cosmetics can be other active substances referred to in paragraph [0066] the description of the German patent DE 102006028549 A1. However, due to the presence in the aqueous phase proposed in the invention of the drugs listed above polyurethanes PU with thickening effect from the use of thickeners listed in paragraph [0066] the quoted document, you can refuse.

In accordance with the present invention, it is preferable to supplementation in the formulations of one or more film-forming agents, polymers respectively, the purpose of which is primarily effective is skin tightening, which can be achieved by the inherent specified additives film-forming properties. However, the film provides fixation of the pigments on the skin, due primarily achieved long-term retention on the skin and lack of migration of the pigments. Suitable according to the invention the polymers, and their content is given in paragraphs [0073] to [0076] the description of the German patent DE 102006028549 A1.

The major components of the preferred proposed in the invention of the drug of type oil-in-water in addition to water, forming the continuous phase of the corresponding emulsion, and used according to the invention polyurethane PU are wax component, a polyhydric alcohol and a system of binders. The wax component comprises at least one wax, and optionally, at least one fat and/or oil, which accordingly can be of vegetable, animal, mineral or synthetic products. To facilitate processing of the wax component in the emulsion of the wax component may further comprise at least one emulsifier and at least one simulator. To achieve results, especially meet the aesthetic requirements, the wax component may further comprise a copolymer vinylpyrrole is it. The wax component ensures the consistency of the composition and makes it resistant to moisture and sitostanol. In this regard, the wax component can be made from fat-like, butter-like and waxy materials, which at temperatures from 21 to 25°C can be in liquid, pasty or solid state. For ustanovlenija optimal consistency it is preferable to use a combination of at least one wax, at least one oil. Preferred waxes are given in paragraphs [0017] and [0018] a description of German patent DE 102006028549 A1, the text of which in full should be considered an appropriate reference. Preferred oils and fats specified in paragraph [0019] of the description of this document in full should be considered an appropriate reference.

Preferably a mixture of waxes, oils and fats in such quantities as to have desired properties, such as structure and viscosity. Appropriate to be used in the number and types of mixtures known in the art, and therefore they do not require more detailed explanation. Preferred amounts of waxes, fats and oils are described in paragraphs [0022] and [0023] a description of German patent DE 102005033520 A1, the text of which in full should be considered an appropriate SS is the left main coronary artery.

Suitable according to the invention polyhydric alcohols described in paragraph [0026] the description of the German patent DE 102005033520 A1, the text of which is in full should be considered an appropriate reference.

Film formers and their quantities used in the proposed invention the preparations for decorative cosmetics, described in paragraphs [0027] to [0030] the description of the German patent DE 10 2005 033 520 A1, the text of which in full should be considered an appropriate reference.

Proposed in the invention, the preparations for decorative cosmetics in addition to used according to the invention the polyurethanes PU can also contain other gel-forming means. Other suitable gelling agent is indicated in paragraph [0032] the description of the German patent DE 102005033520 A1, the text of which is in full should be considered an appropriate reference.

Shampoos, conditioners and cleaning preparations

The preferred embodiment of the invention relates to shampoos and cosmetic cleaning agents containing used according to the invention, the polyurethanes PU. To shampoos and cosmetic cleaning agents depending on hair quality or condition of the scalp if necessary, impose additional requirements. The following is the mechanism of action of shampoos preferred types, ensuring the achievement of the importance of the first additional effects or special purposes.

According to the invention are preferred, for example, shampoos for normal hair, shampoos for hair, quickly becoming oily, shampoo for damaged hair, dandruff shampoos, baby shampoos and shampoos type two-in-one (shampoo + conditioner).

Proposed in the invention shampoos for normal hair

Washing your hair should contribute to the liberation of both the hair and scalp from secreted by the sebaceous glands sebum, inorganic salts secreted by sweat glands together with moisture, amino acids, urea and lactic acid, as well as from exfoliating particles of the skin, external contamination, odor and balances, if necessary, used for the cosmetic treatment of hair. Normal are considered to be only slightly damaged hair, the length of which can reach up to his shoulders. Media content-conditioning in shampoos should be optimized with respect to the hair of the specified type.

Proposed in the invention shampoos for the hair, quickly becoming fat

Observed in this case, increased fat excretion of the sebaceous glands of the scalp leads to the fact that within a day or two after washing hair becomes very unattractive appearance. Butter-like and wax-like components of the skin weight PR is cesku, reduce the friction between the individual hair and reduce the overall stability of hairstyles. Thus, the immediate beauty hair problem of this type is premature spillage voluminous hairstyles. To avoid such problems it is necessary to prevent worsening of the hair and make them smooth and soft. Good results, preferably reach through the use of surface-active substances on the basis of particularly effective detergent raw materials that can be entered into the composition of shampoos smaller amounts of surfactants. Additional funds for skin care, for example, substances for recovery of oily skin, as well as auxiliary conditioning means, which may be combined with the action of sebum in the composition of shampoos to wash your hair, quickly becoming fat, not used or used only with great caution. According to the invention is comparable composition may have shampoos designed for washing hair is fine.

The proposed invention in shampoos for dry and damaged hair In the process of hair growth due to mechanical pressures when brushing, brush processing and above all topoloveni (brushing against the direction of growth), due to the hcpa is istia of ultraviolet and visible light, and also due to cosmetic treatment, such as perming, bleaching or dyeing, there is a change of the hair structure. In such cases, scaly layer of hair from roots to ends looks largely broken, and in extreme situations may be completely absent, which leads to splitting of hair ends. To return the damaged hair in typical healthy hair condition by using the proposed invention shampoos in principle not possible. However, washing your hair these shampoos allows substantially to bring their condition (vulture, brilliance and ability to scratching) to the ideal, which is achieved by optionally implemented to improve the content providing care components (air-handling of funds).

An even better effect compared with the effect of the shampoo reaches through the hair treatment proposed in the invention means for care of hair, for example, in the form of a mouthwash or drug treatment, and such treatment should be done after washing your hair. Rinses or therapeutic agents for the hair, containing proposed in the invention polymers, are also the object of the present invention.

Proposed in the invention shampoo "two in one" (song on the frame type are also shampoos and conditioners) allow for particularly high-quality hair care, because the main effect of hair washing is combined with the effect of conditioning. Proposed in the invention compositions of the type "two in one" contain increased amounts of the conditioning means.

Shampoos for dandruff

The advantage of the proposed invention shampoos for dandruff compared with special antisubmarine liquids is that due to the presence of the first active substances that prevent dandruff, they not only limit its appearance (at long-term use to prevent its re-appearance), but also removes flaking during washing dandruff. After rinsing the scalp and the hair remains a small but sufficient amount of active substances. There are various active ingredients of dandruff that you can enter in the proposed invention the formulations of shampoos, such as zinc pyrithione, ketoconazole, clotrimazole, climbazol or piroctone alamin. Such substances have the ability to normalize the process of exfoliation of dandruff.

Based shampoos for dandruff mainly lies in the formulation of shampoos for normal hair with optimal washing effect.

Baby shampoos

In accordance with a preferred embodiment of the invention under p is adegeye in the invention shampoos mean baby shampoos. They have the best compatibility with skin and mucous membranes. The basic principle of formation of the relevant formulation is a combination of detergent raw materials, which have an extremely high compatibility with the skin. In appropriate formulations of the additive is preferably introduced to further improve compatibility with skin/mucous membranes and improved conditioning properties, such as non-ionic surfactants, protein hydrolysates, panthenol or bisabolol. Any of the original components and excipients appropriate formulations, such as preservatives, perfume oils, dyes and so on, chosen, taking into account the need to ensure high compatibility and softness.

Shampoos for dry scalp

The main purpose of this shampoos is to prevent dehydration of the scalp, which may be accompanied by itching, redness and inflammation. Like children's shampoos basic principle of the formation of the relevant formulation is a combination of detergent raw materials, which have an extremely high compatibility with the skin. If necessary, in appropriate formulations can additionally include means for recovering oily skin and humectants, such as glycerol or urea.

Preferred shampoos and cosmetic detergents contain anionic surfactants. Other preferred shampoos and cosmetic detergent products contain a combination of anionic and amphoteric surfactants. Other preferred shampoos and cosmetic detergent products contain combinations of anionic and zwitter-ionic surfactants. Other preferred shampoos and cosmetic detergent products contain combinations of anionic and nonionic surfactants.

Suitable surfactants of all types discussed above.

Preferred anionic surfactants according to the invention are the alkyl sulphates, alkylpolyglycoside and salt aircarbon acids with 10 to 18 carbon atoms in the alkyl group and up to twelve groups of glycol ether in the molecule, monocrome and dialkyl ethers sulfonterol acid of 8-18 carbon atoms in the alkyl group and monoacylglycerol esters sulfonterol acid of 8-18 carbon atoms in the alkyl group and 1 to 6 oxyethyl groups. Particularly preferred anionic surfactants are alkali or ammonium salt of laurylsulfate with a degree of amoxilonline from 2 to 4 ethyleneoxide units.

Preferred zwitter-ionic surface-active agent is according to the invention is an amide derivative of a fatty acid called according INCl cocamidopropyl betaine.

Particularly preferred amphoteric surfactants according to the invention are n-cocoalkylamine, kokosalkilammonia-piont and azilsartan 12 carbon atoms in the alkyl.

Preferred non-ionic surfactants according to the invention are addition products alkalisation to rich of neravetla th aliphatic alcohols and fatty acids, respectively, containing from 2 to 30 moles of ethylene oxide per mole of aliphatic alcohol or fatty acid. Excellent properties are also drugs that are as non-ionic surfactants include esters based on fatty acids and ethoxylated glycerin.

Proposed in the invention shampoos can also be in the form of concentrates, the content of surfactant in which higher than normal by the amount of 20%to 30%. The basis of such concentrates are a special combination of detergents raw materials and regulators consistency, ensuring optimal distribution of components and the ability of the shampoo to spontaneous foaming, including when it is applied in small quantities. A particular advantage of such concentrates is, for example, that due to the use of packaging volume of 100 ml, you can achieve results similar to the packaging volume of 200 ml.

Form of application

<> Proposed in the invention, the preparations can be used, for example, in the form of money, put up in aerosol tanks or compressed gas cylinders, in the form of tools, spray spray or foaming device, and means applied from the usual bottles and vessels. As a propellant for spraying a cosmetic or dermatological preparatov of aerosol tanks in accordance with the present invention using conventional known volatile liquefied working medium, for example, dimethyl ether, or hydrocarbons (propane, butane, isobutane), individually or as mixtures with each other. Preferably you should use compressed air, nitrogen, nitrogen dioxide, carbon dioxide or mixtures of these gases.

Preparation proposed in the invention of drugs can be accomplished by conventional methods by mixing the individual components.

Active ingredients included in the composition proposed in the invention of drugs, as well as pre-mixed components proposed in the invention of drugs can be added in the mixing process. The pH of the proposed invention in preparations you can install the known methods, providing for the filing of an acid or base, preferably a buffer mixtures, for example, on the basis of the lemon is Oh acid/citrate or phosphoric acid/phosphate. The pH of the proposed invention in the preparations is preferably less than 10 and is, for example, in the range from 2 to 7, especially from 3 to 5.

Preferred formulations of shampoos include the following components:

a) from 0.05 to 10 wt%. at least one polyurethane PU,

b) from 25 to 94,95% of the mass. water,

c) from 5 to 50 wt%. surfactants,

d) from 0 to 5% of the mass. conditioning means,

e) from 0 to 10% of the mass. other cosmetic components.

In accordance with another embodiment of the invention through the use of the above polyurethanes PU drugs with sufficient viscosity, you can also create based formulations with low content of surface-active substances (less than 10% of the mass. Surfactants in terms of the drug). The polyurethanes PU primarily allow you to set the desired viscosity of the preparations, which contain at least 0.1% of the mass. salt and from 0.1 to 10 wt%. preferably less than 10 wt% surfactant.

In shampoos and cosmetics detergents you can use any normally used in such preparations anionic, neutral, amphoteric or cationic surfactants. Suitable surfactants described above. Especially preferred are the shampoos and cosmetic cleaning agents, the content of the surfactant is more than 10% of the mass.

To achieve certain effects in the formulation of shampoos you can use a regular conditioning means. Suitable conditioning means include, for example, cationic polymers, called according to nomenclature INCl polyquaternium, especially copolymers of vinylpyrrolidone with salts of n-vinylimidazole (products LUViquat®FC, LUViquat®HM, LUViquat®MS and LUViquat®Care), copolymers of n-vinylpyrrolidone with dimethylaminoethylmethacrylate, quaternions diethylsulfate (product LUViquat®PQ 11), copolymers based on n-vinylcaprolactam, n-vinylpyrrolidone and salts of n-vinylimidazole (LUViquat Hold), cationic cellulose derivatives (polyquaternium-4, polyquaternium-10), as well as copolymers of acrylamide (polyquaternium-7).

Preferred conditioning means are, for example, compounds called according to the nomenclature INCl polyquaternium (primarily the number of connections from polyquaternium-1 to polyquaternium-87). The following table lists the conditioning means used in combination with the above polyurethanes PU, which is not ogranichetsya listed in table representatives.

Name according INClThe number in Chemical AbstractsType polymer clay is and Example (trade name)
Polica-thorns-2CAS 63451-27-4Urea, N,N', bis[3-(dimethylamino)propyl] -, polymer with 1,1'-oxybis-(2-chlorethane)Merquat®A-15
Polica-thorns-5CAS 26006-22-4Acrylamide, β-methacryloxyethyl-triethylammonium methosulfate
Polica-thorns-6CAS 26062-79-3N,N-dimethyl-N-2-propenyl-2-propanamine chlorideMerquat®100
Polyquaternium-7CAS 26590-05-6N,N-dimethyl-N-2-propenyl-2-propanamine chloride, 2-propen-amideMerquat®S
Polyquaternium-10CAS 53568-4, 55353-19-10, 54351-50-7, 68610-92-4, 81859-24-7Quaternary ammonium salt of hydroxyethyl celluloseCelquat®SC-230M, Polymer JR 400
Polica-thorns-11CAS 53633-54-8The product of the interaction of diethyl sulfate and a copolymer of vinyl-pyrrolidone with dimethylamino-Edelmetalle the Ohm Celquat®755N
Polica-thorns-16CAS 29297-55-0Copolymer of vinyl pyrrolidone/VI-delimitation methochlorideLUViquat®HM552
Polica-thorns-17CAS 90624-75-2Mirapol®AD-1
Polica-thorns-19CAS 110736-85-1Quaternionic water-soluble polyvinyl alcohol
Polica-thorns-20CAS 110736-86-2Water-dispersible quaternionic polivinilbutilovy ether

Name according INClThe number in Chemical AbstractsThe type of polymerExample (trade name)
Polica-thorns-21The copolymer of polysiloxane/polidi-methyldiethylamine acetateAbil®In 99905
Polica-thorns-22CA 53694-17-0 The copolymer of dimethylallyl-money chloride/acrylic acidMerquat®280
Polica-thorns-24CAS 107987-23-5Polymer kvaternikova ammonium salt of hydroxyethyl-celluloseQuartisoft®LM-200
Polica-thorns-28CAS 131954-48-8The copolymer vinylpyrrole-don/Methacrylonitrile-methylammonium chlorideGafquat®HS-100
Polica-thorns-29CAS 92091-36-6, 148880-30-2Chitosan is subjected to interaction with propylene oxide and quaternionic epichlorhydrin-Mr.Lexquat®CH
Polica-thorns-31CAS 136505-02-7, 139767-67-7Polymer kvaternikova ammonium salt, obtained by the interaction of the copolymer DMAPA-acrylate/acrylic acid/Acrylonitrile with diethylsulfateHypan®QT 100
Polica-thorns-32CAS 35429-19-7Copolymer of N,N,N-trimethyl-2-{[82-methyl-1-oxo-2-propenyl)-oxy)}of ethanaminium chloride/2-Pro is ename
Polica-thorns-37CAS 26161-33-1
Polica-thorns-44Quaternary ammonium salt of a copolymer of vinylpyrrolidone with quaternions imidazoline
Polica-thorns-67The product of the interaction of polymeric Quaternary ammonium salt of hydroxyethyl cellulose with an epoxide substituted ammonium, and an epoxide substituted by lauryldimethylamineSoftCAT®
Polica-thorns-74Polycare®Boost
Polica-thorns-87LUViquat®Sensation

In addition, you can use protein hydrolysates, as well as the conditioning substances based on silicone compounds, for example, polyallylamine, polyacrilamide, polyallylamine, polyethylsiloxane or polysiloxane. Other suitable silicone compounds which deposits are Dimethicone copolyol (named according to the nomenclature of the Association for perfume and cosmetic products and fragrances - CTFA), and amidofunctional organosilicone compounds, such as amodimethicone (CTFA).

Proposed in the invention shampoos and cosmetic detergents preferably contain salt. Proposed in the invention shampoos and cosmetic cleaning agents on the basis of anionic surfactants preferably contain sodium chloride. A particular advantage of the present invention is that the viscosity and appearance of the proposed invention in shampoos and cosmetics detergents remain unchanged for long periods of time when the sodium chloride concentrations of more than 0.2% of the mass. and/or concentration of surface-active substances more than 10% of the mass.

In addition, in another preferred embodiment of the invention shampoos and cosmetic detergent products contain at least one component selected from the group comprising water-insoluble oil components, vitamins, Pro-vitamins, protein hydrolysates, plant extracts, UV filters, amino acids, water-insoluble silicones, water-soluble silicones and/or amodimethicone.

The total number of oil and fat components in the proposed invention the formulations of shampoos usually ranges from 6 to 45% of the mass. in terms of preparation. The preferred amount of these components is now according to the invention comprise from 10 to 35% of the mass.

According to the invention under the preferred vitamins, provitamins and their derivatives involve representatives of relevant groups a, b, C, E, F and N. Used according to the invention the preparations preferably contain vitamins and provitamins, who are representatives of the respective groups a, E, F and N. In the proposed invention the drugs, obviously, there may be multiple vitamins and provitamins. The total number of vitamins, provitamins and their derivatives used in the present invention the drugs, is from 0.01 to 5% by mass. preferably from 0.02 to 4% of the mass. and especially from 0.05 to 3 wt%. in terms of the total weight of the preparation.

Proposed in the invention shampoos and cosmetic detergents preferably contain protein hydrolysates. In accordance with the present invention under protein hydrolysates mean protein hydrolysates and/or amino acids and their derivatives. Protein hydrolysates are mixtures of products that are formed as a result catalyzed by acids, bases or enzymes cleavage of protein. According to the invention under protein hydrolysates also involve products of complete hydrolysis of the amino acids, their derivatives or mixtures of different amino acids and the product of the hydrolysis of individual amino acids and their derivatives. In addition, according to the invention under protein hydrolysates mean polymers composed of amino acids and derivatives of amino acids. The latter include, for example, polyalanine, polysporin, policemen and so on. Examples of other used according to the invention compounds are L-alanyl-L-Proline, polyglycine, glycyl-L-glutamine and chloride D/L-methionine-β-methylsulfone. According to the invention, obviously, you can also use β-amino acids and their derivatives, such as β-alanine, astralnova acid or hippuric acid. The molecular weight used according to the invention the protein hydrolyzate is in the range from 75 Yes (molecular weight of glycine) to 200,000 Da, preferably in the range from 75 to 50,000 and more preferably from 75 to 20,000 Da.

Preferred protein hydrolysates described in paragraphs [0077] on [0079]as their preferred amount in paragraph [0080] DE 102006032505 A1. The text of these paragraphs in full should be considered an appropriate integral link.

According to the invention containing surfactants detergents means, first of all shampoos, preferably present in the plant extracts. Preferred plant extracts are given in paragraphs [0081] [0082]as their preferred amount in paragraph [0086] the description of the German patent DE 10200632505 A1. The text of these paragraphs in full should be considered an appropriate integral link.

According to the invention are preferred which contains surfactants detergents, especially shampoos, which contain UV-light protection means (UV filters). UV filters can increase the effects of drugs. A list of suitable according to the invention UV-filters in General is not limited to compounds having a specific structure and physical properties. Suitable are any used in the field of cosmetic UV filters, maximum absorption is in the region of UVA (315-400 nm), UVB (280-315 nm) or UVC (below 280 nm) of the spectrum. Especially preferred are UV filters, maximum absorption is in the approximate range from 280 to 300 nm. Suitable according to the invention UV-filters can be selected from the group including, for example, substituted benzophenone, esters of p-aminobenzoic acid, esters diphenylacetone acid, esters of cinnamic acid, esters of salicylic acid, benzimidazole and esters of o-aminobenzoic acid.

The examples used according to the invention the UV filters listed in paragraph [0089] the description of the German patent DE 10 2006 032 505 A1. The specified text in full should be considered an appropriate integral link.

p> According to another preferred variant of the invention, shampoos and cosmetics detergents also contain at least one other water-insoluble silicone, water-soluble silicone and/or aminobenzenesulfonic silicone. Suitable according to the invention, the silicones have a variety of effects. For example, they simultaneously have an impact, for example, on the suitability of the hair for combing in the dry and wet States, and the neck dry and wet hair and Shine. Under silicones experts imply organosilicon compounds with the structure of several types.

Preferred silicones described in paragraph [0113] the description of the German patent DE 102006032505 A1. The specified text in full should be considered an appropriate integral link.

According to another preferred variant of the invention, shampoos and cosmetics detergents also contain at least one emulsifier. Preferred emulsifiers are given in paragraph [0147]as their preferred amount in paragraph [0148] the description of the German patent DE 102006032505 A1. The text of these paragraphs in full should be considered an appropriate integral link.

According to another preferred variant of the invention, the shampoos and Cosmas the practical detergents also contain at least one other polymer. Preferred other polymers described in paragraphs [0151] to [0165]as their preferred amount in paragraph [0167] description DE 102006032505 A1. The text of these paragraphs in full should be considered an appropriate integral link.

Proposed in the invention shampoos and cosmetic detergents can also contain organic solvents, such as ethanol, propanol, isopropanol, benzyl alcohol, benzyloxyethanol, ethoxydiglycol, alkalescency, in particular, ethylene carbonate resulting propylene-carbonate, Phenoxyethanol, butanol, Isobutanol, cyclohexane, cyclohexanol, hexyleneglycol, ethylene carbonate resulting, propylene glycol, polypropylene glycols, monotropy ether of ethylene glycol (ethyl cellosolve), monobutyl ether of ethylene glycol, monopoloy ether of ethylene glycol, 1-phenethyl alcohol, 2-phenethyl alcohol and o-methoxyphenol. Particularly preferred organic solvents are benzyl alcohol, benzyloxyethanol and propylene glycols. The amount of organic solvent contained in the proposed invention the drugs should be no more than 5% of the mass. and preferably is in the range from 0.1 to 3%, particularly preferably from 0.5 to 2.5 wt%. in terms of preparation.

In the composition of cosmetic products you can optionally enter girotropnye the solubilizer is, especially if such products contain oily substances as a means of care and aromatic oils with high lipophilicity. Typical used hydrotropism soljubilizatorami are hydrogenated tall oil (for example, product Cremophor®RH). It should be noted that good hydrotroilite soljubilizatorami for aromatic oils can also be a mixture of surfactants. The normal amount of hydrotropic of solubilization can be from 0.01 to 2% of the mass. first of all, from 0.1 to 1% of the mass. in terms of the overall composition.

Other preferred ingredients of the invention in shampoos and cosmetics detergents referred to in paragraph [0168] description DE 102006032505 A1. The specified text in full should be considered an appropriate integral link.

According to the invention particularly preferred are shampoos and cosmetic cleaning agents, which contain at least one of the above polyurethane PU as a thickener, at least one alkylsulfate and/or alkylsulfonates (for example, sodium lauryl sulphate) and at least one Quaternary ammonium salt (for example, dihydrophosphate acidimeter-(2)-hydroxyethylamine). Thanks to the use of polyurethane PU these preparations may be prepared in the form of colorless prose is achnyh compositions that is not possible when using conventional carbonero.

Preparations deodorants or antitranspirants

In a preferred embodiment, the present invention relates to preparations deodorants or antitranspirants primarily to deodorant lotions and pencils as deodorants, or antitranspirants based dispersion/emulsion of the type oil-in-water intended for the application of the relevant active substances, especially water-soluble active substances on the skin. The use of the polyurethanes of the type specified above allows to make preparations deodorants or antitranspirants in the form of microscopic specimens, micropreparative, creams and sprays.

Graduation forms of market preparations deodorants or antitranspirants in most cases are sprays or cosmetic pencils, in addition to produced the corresponding ball medications and creams. Antitranspirant usually put on the market in various forms, and in Europe is dominated by ball applicators, pulverizeroaiu drugs and aerosols, while in the United States and the countries of Central and South America the main discharge form antitranspirant are pencils. Known as anhydrous and water-containing product (hydroserve formulations, emulsions). P is intitially problems containing antitranspirant emulsions due to the destabilizing effect of high content of electrolytes, that applies especially for drugs with low pH. As a consequence, the corresponding emulsions do not have long-term stability and often sedimentary. A similar phenomenon is primarily characteristic of low viscosity flowable emulsions. However, some consumers predpochitayut exactly this type of drugs.

Many drugs antitranspirants produced in the form of anhydrous suspension of pencils. When Petrasiunai to the skin after the use of such drugs among consumers remains a pleasant feeling of dryness. However, the efficiency of the allocation of free water-soluble active substances against sweat (substances that have the effect of antitranspirants) of these drugs are limited to a certain limit (see Chemistry and Technology of The Cosmetics and Toiletries Industry, publishers D.F. Williams and W.H. Schmitt, London, Blacie, 1996, 2nd edition, s), and therefore many consumers often do not feel a pleasant sensation of freshness after their application. The lack of anhydrous drugs, especially drugs on the basis of volatile silicone oils, is that dispersed them active substances left on the skin and clothing visible traces. In addition, these drugs have a relatively high cost because of the oil components used as the basis of the s active substances, more water. Under the action used when applying such pressure drugs often observed stratification of the drug, which reduces its beauty suitability.

Used according to the invention, the polyurethanes PU preferably have the effect of thickeners primarily in preparations deodorants and antitranspirants with high concentrations of electrolyte and/or acid preparations deodorants and antitranspirants. The polyurethanes PU preferably should be used in the preparations as thickeners especially when the salt content is higher than 3% of the mass. preferably more than 5% of the mass. accordingly, calculated on the total preparation.

The polyurethanes PU preferably should be used as thickeners in particular if the pH of the preparation is in the range from 3 to 6, preferably from 4 to 5.5.

The use of polyurethanes PU allows to obtain a stable cosmetic and/or dermatological preparations with active ingredients against sweat, such as aluminofluoride, primarily if the pH is between 3.5 and 6.

The dissolution of the active substance against sweat in the external continuous aqueous phase of the preferred drugs of type oil-in-water" makes much more efficient is the second release of this substance in comparison with the known anhydrous preparations first of all, compared with the suspension pencils and pencils on the basis of emulsions of water in oil.

Quick and simple method of determining the difference between the systems of the type oil-in-water" and "water in oil" is also the measurement of electric resistance of the respective compositions. System type oil-in-water due to the presence of the continuous aqueous phase is characterized by high electrical conductivity and therefore a low electric resistance. In this case, the release of the active substance can very easily installed by direct measurement of electrical resistance of the corresponding drug.

Preparation of the considered drugs in the form of dispersions/emulsions of the type oil-in-water" in addition to optimal release of active substances allows to achieve other advantages. Firstly, this song is easily washed off from the skin surface. And, secondly, during the application or after application to the skin it together with the moisture of the skin forms a cream-type oil-in-water, which has a caring action, which allows Petrasiunai to the skin occurs refreshing and cooling effect.

In a preferred embodiment of the invention proposed in the invention, the preparations deodorants and antitranspirants, primarily CT is ndasi, contain lipids and/or wax. Suitable lipids and waxes are given in paragraphs [0033] to [0041] the description of the German patent DE 102006021780 A1, the text of which in full should be considered an appropriate reference.

Preferred lipid or wax component a) is chosen from the group comprising esters on the basis of a saturated monohydroxy alkanols in 16-60 carbon atoms and saturated monocarboxylic acids with 8-36 carbon atoms, especially clivehunt, stearylamine and alterstart with 20-40 carbon atoms in the alkyl, truefire of glycerol and saturated linear carboxylic acids with 12 to 30 carbon atoms, which may be gidroksilirovanii, candelilla wax, Carnauba wax, beeswax, saturated linear carboxylic acids with 14-36 carbon atoms, and mixtures of these substances. Particularly preferred mixtures of lipid or wax component a) is chosen from the group comprising a mixture of clivehunt, stearylamine, cured castor oil, palmitic acid and stearic acid. Other particularly preferred mixture of the lipid or wax component a) is chosen from the group comprising a mixture of ancilliaries with 20-40 carbon atoms in the alkyl, utverjdenie castor oil, palmitic acid and stearic acid. Other preferred proposed in the invention of drugs which s deodorants and antitranspirant tov in the form of pencils differ in the that the total quantity contained in the lipid or wax component a) is from 4 to 20% of the mass. preferably from 8 to 15% of the mass. in terms of the overall composition. In a particularly preferred variant of the invention, the content of esters on the basis of a saturated monohydroxy alcohols with 50-60 carbon atoms and saturated monocarboxylic acids with 8-36 carbon atoms used in the present invention the preparations deodorants and antitranspirants as lipid or wax component a), sostavljaet from 2 to 10% of the mass. preferably from 2 to 6% of the mass. in terms of the overall composition.

The preferred proposed in the invention, the preparations deodorants and antitranspirants contain at least one non-ionic emulsifier of the type oil-in-water" indicator hydrophilic-lipophilic balance of more than 7. It is about the emulsifiers, generally known in the art and described, for example, in Kirk-Othmer, "Encyclopedia of Chemical Technology", 3rd edition, 1979, volume 8, cc.913-916. Figure hydrophilic-lipophilic balance (HLB) ethoxylated products is calculated by the formula HLB=(100-L):5, and L is expressed in mass percent share of lipophilic groups, i.e. the proportion of the alkyl or acyl groups in the adducts of ethylene oxide.

Suitable emulsifiers of type oil-in-water" given in paragraphs [0044] to [0050], is their preferred amount in paragraph [0051] the description of the German patent DE 102006021780 A1, the text in full should be considered an appropriate reference.

In addition, the preferred proposed in the invention, the preparations deodorants and antitranspirants contain at least one non-ionic emulsifier of the type "water in oil" indicator hydrophilic-lipophilic balance in the range from 1.0 to 7.0.

Suitable emulsifiers of the type "water in oil" is given in paragraphs [0053] to [0056], and their preferred quantity in paragraphs [0057] [0058] the description of the German patent DE 10 2006 021 780 A1, the text of which in full should be considered an appropriate reference.

The preferred proposed in the invention, the preparations deodorants and antitranspirants preferably contain at least one oil. Suitable oils are given in paragraphs [0062] to [0066] in paragraph [0073] the description of the German patent DE 102006021780 A1, the text of which in full should be considered an appropriate reference.

The preferred proposed in the invention, the preparations deodorants and antitranspirants preferably contain at least one polyol. Suitable polyols described in paragraphs [0080] and [0081] a description of German patent DE 102006021780 A1, the text of which in full should be considered an appropriate reference.

The preferred proposed in the invention, the preparations deodorants and antitranspirants with the, also may contain at least one deodorant active ingredient (deodorant) and/or active substance against sweat (antitranspirant).

According to the invention preferred deodorant active ingredients are scavengers naradnogo smell, ion-exchange substances with a deodorizing effect, a means for inhibiting the propagation of bacteria, prebiotics existing components, as well as enzyme inhibitors or, particularly preferably, combinations of these active substances. Suitable deodorant active substances described in paragraphs [0087] to [0093] the description of the German patent DE 102006021780 A1, the text of which in full should be considered an appropriate reference. The number of these active ingredients (one or more compounds)contained in predlagau made in the invention the preparations is preferably from 0.01 to 10 wt%. particularly preferably from 0.05 to 5% by mass. first of all, from 0.1 to 1 wt%, calculated on the total weight of the preparation.

The preferred proposed in the invention, the preparations deodorants or antitranspirants differ in that at least one substance to the action of antitranspirant chosen from the group comprising water-soluble astringent inorganic and organic salts of aluminum, zirconium or zinc, respectively, any mixtures of these salts. Suitable active ingredients are antitranspirant described in paragraphs [0095] and [0096] a description of German patent DE 102006021780 A1,the text of which in full should be considered an appropriate reference.

In another particularly preferred embodiment of the invention proposed in the invention of drugs as the active substance may contain at least one deodorant, and at least one antitranspirant.

The preferred proposed in the invention, the preparations deodorants and antitranspirants can also contain low-melting lipid or wax components referred to in paragraph [98] describe German patent DE 102006021780 A1, the text of which is in full should be considered an appropriate reference.

The preferred proposed in the invention, the preparations deodorants and antitranspirants can also contain fillers, described in paragraphs [100] and [101] describe German patent DE 102006021780 A1, the text of which in full should be considered an appropriate reference.

The preferred proposed in the invention, the preparations deodorants and antitranspirants also contain fragrances that are listed in the paragraphs from [105] [108] describe German patent DE 102006021780 A1, the text of which in full should be considered an appropriate reference.

The preferred proposed in the invention, the preparations deodorants or antitranspirants in the form of pencils are different in that they also contain pigments, e.g. titanium dioxide. The presence of pigments pic is of bstweet higher cosmetic acceptability of these drugs to the consumer. In addition, especially preferred proposed in the invention deodorants and antitranspirant in the form of pencils differ in that they contain the usual components of cosmetic preparations, for example, dyes, nanohelices particles, preservatives, light stabilizers, antioxidants, enzymes and substances for skin care. The preferred content of the above components in a particularly preferred proposed in the invention pencils-deodorants and pencils-antitranspirant is from 0.001 to 20 wt. -%

To stabilize these drugs, you can use the above antioxidants, acceptors of free radicals, UV filters, komleksoobrazovateli and preservatives.

In one of the embodiments of the invention the preparations deodorants or antitranspirants contain inhibitors of hair growth. Suitable inhibitors of hair growth referred to in paragraph [0120] the description of the German patent DE 102006021780 A1, the text of which is in full should be considered an appropriate reference.

Tools, hair coloring

In addition, the above polyurethanes PU primarily suitable for use as thickeners containing peroxide preparations, such as hair coloring tools. Thus, another variant of implementation of the present invention apply the means of colouring hair containing used according to the invention, the polyurethanes PU, as well as to the use of polyurethanes PU in the means of coloring as thickeners. The use of polyurethanes PU primarily allows you to create netekusia in the form of droplets and/or netnumina in the form of threads in the system.

Composition (means) hair coloring depending on the resistance created by them painting can be divided into three groups: temporary means of maintaining only one or two operations of washing your hair, semi-permanent funds staining which requires updating after eight to ten operations of washing your hair, and permanetly funds provided through which the effect of dyeing hair cannot be eliminated by washing.

Temporary and semi-permanent hair coloring tools called non-oxidative means. When coloring hair means such dyes are deposited on the keratin of the hair or penetrate them. In the case of hair coloring permanetely means that you undoubtedly are the most common means of dyeing hair dye is formed directly on the hair and within source of colorless substances from leaking chemical reaction in the presence used as the oxidizing means of hydrogen peroxide. While the origin Taiwan is the CIO full coverage of hair, and the paint is impossible to remove them by washing. A similar tool called oxidative means of hair coloring.

Hair coloring provided by permanetly funds colouring, extremely resistant to washing, exposure to light and other methods of treating the hair. Permanete means of hair coloring are the most widespread on the market: they accounted for about 80% of all market funds coloring hair. Update created it using colouring in connection with the growth of hair should be about a month. In the case of using such systems dyeing dyes are formed directly on the hair and inside them as a result of chemical interactions involving unpainted intermediate products, respectively, of the original products. In the presence of ammonia or monoethanolamine flow caused by hydrogen peroxide oxidation reactions and processes combinations, respectively condensation. The need to use hydrogen peroxide as the oxidizing means is due to the fact that he not only initiates the formation of the dye, but also destroys the melanin pigment of the hair and, thus, contributes to their discoloration, and therefore consider the coloring process is also called lightening about what rochevalium.

To permanetly means of hair coloring in principle should include also the so-called samoochischayuschiesya dyes that oxilate by oxygen in the air.

Means of hair coloring are usually in the form of water, preferably thickened solutions or emulsions, which in addition to dyes include, for example, aliphatic alcohols and/or other oil components, emulsifiers and surfactants, and optionally alcohols.

Tools oxidative hair coloring generally consist of two components, which are:

(A) containing a dye material-based dyes and

(B) preparation of oxidizing means.

These components are mixed shortly before use, and then apply to be dyeing fiber.

Common forms of using such funds permanence or oxidative dyeing are cream hair dyes, gels for hair coloring and coloring shampoos. To ensure the presence of the active ingredients of coloring compositions on the hair for a certain period of time after application, and their absence in those places where they are unwanted, for example, on the face, coloring composition should have a certain minimum viscosity. The required viscosity of the coloring compositions typically bespechivaet through the use of thickeners, which, therefore, are an important component of most of the funds for the oxidative dyeing of hair.

As thickeners typically use crosslinked polyacrylic acid (e.g., product Carbopol®), hydroxyethyl cellulose, wax and features a mixture with a certain measure of hydrophilic-lipophilic balance of nonionic surfactants and anionic, cationic or non-ionic associated polymers. Due to the fact that the part of the preparations for hair coloring has an extremely high salt content, the usual widely used system of thickeners based surfactants, as well as on the basis of polyacrylic acid often lack the ability to make these drugs the required viscosity. In addition to small tolerance thickeners based on polyacrylic acid with respect to the salts they have other disadvantages, one of which is that processed containing drugs hair is not necessary leave a pleasant sensation when Petrasiunai. In addition, the use of such drugs is often not possible to ensure adequate and uniform dyeing of the hair, i.e. staining with the most insignificant selectivity, however, does not allow to ensure the tested favorable cosmetic condition of the hair. The viscosity of the coloring compositions often do not possess adequate stability and decreases in time, and therefore the means of coloring not adhesive on the hair, and flow to those areas of the scalp where the staining is undesirable.

Thus, the present invention was to provide thickeners for containing water intended for dyeing keratin fibers cosmetic compositions that would provide a sufficiently high viscosity of such compositions, allowing last for a long time to stay on subject to paint. Zahodenie such thickeners coloring composition should not drain from the hair in the form of drops, must be effectively and uniformly, i.e. with the most insignificant selectivity to paint the hair, and also to provide them with favorable cosmetic condition. Such thickening action must be maintained at a sufficiently high level, above all at high concentrations of salt (electrolyte).

In the preferred proposed in the invention the preparations for dyeing keratin fibers used according to the invention polyurethane PU is initially at pH from 1 to 4, preferably from 2 to 3 is preferably a peroxide component is E. After mixing this component with the component containing the source material for dye, polyurethane PU is in a mixture at pH 7 to 12, preferably from 8 to 10, particularly preferably from 8.5 to 9.5 and above all about 9.

Cosmetic composition for dyeing hair containing polyurethane PU, can be easily prepared in the form of gels, which have a very favorable combination of properties.

Proposed in the invention, cosmetic preparations for dyeing keratin fibers preferably contain from 0.05 to 10 wt%. particularly preferably from 1 to 7% of the mass. and especially from 2 to 6% of the mass. at least one polyurethane PU in terms of preparation.

A preferred object of the present invention is a cosmetic composition for dyeing keratin fibers, comprising at least two components (a) and (B)

moreover, component (A) is at least one oxidative dye,

and component (b) contains at least one oxidizing agent and at least one used according to the invention polyurethane PU.

In a preferred embodiment, components (a) and (b) are prepared separately from each other and result in mutual contact, no more than 30 seconds, preferably not more than 20 seconds before applying to the keratin fibers.

Com is onent (a) and/or (C) as a thickener may contain polyurethane PU. In a preferred embodiment of the invention, polyurethane PU is present in the component (B).

Oxidative dyes

These are compounds that are in the initial state are not dyes in the truest sense of the word, and are the initial products for the dye, which according to their chemical properties can be divided into oxidized bases (the developers) and coupler (shielding) components.

Oxidized bases are aromatic compounds which are substituted in the nucleus by at least two radiating electrons groups (e.g. amino groups and/or hydroxyl groups) and therefore can easily oxidize.

Important representatives of oxidized bases are p-phenylenediamine and o-phenyldiamine, p-aminophenol, and o-aminophenol, p-dihydroxybenzene and o-dihydroxybenzene and many derivatives of these compounds, formed by, for example, by replacing the amino group by a methoxy group or replacement of the benzene ring other ring systems, such as pyridine, indole, quinoline, and so on.

However, the dominant position as grounds oxidative dyes occupy p-phenylenediamine and p-toluylenediamine.

Color-forming components are aromatic compounds, rings are similarly oxidized bases who will win easily oxidizable groups (amino and/or hydroxyl group), which, however, are in meta-position. Important cotobro-based components are m-phenylenediamine, m-aminophenol and m-dihydroxybenzoic.

Proposed in the invention means the hair coloring preferably contain source materials for oxidative dyes, staining which occurs under the action of oxidizing agents, e.g. such as hydrogen peroxide, or in the presence of oxygen.

Suitable initial agents for the oxidative dyes are, for example, the following manifest and coupler substances and combined themselves with a connection.

Suitable developer substances are listed, for example, in international application WO 02/00181 from line 34 on p.8 on line 28 C, and in paragraph [0015] of the description of the German patent DE 10351842 A1, moreover, these texts should be fully considered by the relevant links.

Suitable coupler substances are listed, for example, in international application WO 02/00181 from line 30 on s on line 14 on page -14, as well as in paragraph [0016] of the description of the German patent DE 10351842 A1, and these texts in full should be considered relevant links.

The total number contained in the proposed invention the composition of the starting substances for the oxidation dye is in an approximate range from 0.0 to 12 wt. -%, first of all, from 0.2 to 6% of the mass.

In addition, for certain color shades in the proposed in the invention compositions may be natural and/or synthetic direct dyes, for example, so-called vegetable dyes such as henna or Indigo, triphenylmethane dyes, aromatic microcrystal, azo dyes, quinone dyes, and cationic or anionic dyes.

Suitable synthetic dyes described, for example, in paragraphs [0017] to [0019] of the description of the German patent DE 10351842 A1, the text of which in full should be considered an appropriate reference.

In the case of presence in the proposed invention the preparations of direct dyes and their content is in an approximate range from 0.01 to 7 wt%. preferably from 0.2 to 4% of the mass. in terms of preparation.

Other known and conventional dyes for dyeing the hair, which may be present in the proposed invention the drugs are given, in particular, in .Sagarin, "Cosmetics, Science and Technology", Inter-science Publishers Inc., New York (1957), cc.503 and following, H.Janistyn, "Handbuch der Kosmetika und Riechstoffe", volume 3 (1973), cc.388 and following, and K. Schrader,,Grundlagen und Rezepturen der Kosmetika", 2nd edition (1989), cc.782-815, which should be considered relevant links.

Although oxidative hair coloring tools are PR is doctitle, proposed in the invention composition can obviously also be in the form of a non-oxidizing coloring means on the basis of the above direct dyes.

The preferred proposed in the invention of drugs as components (a) and (b) contain:

(A) at least one showing agent, at least one additional coupler substance and/or at least one direct dye, and

(B) at least one oxidizing agent and at least one used according to the invention polyurethane PU.

Another object of the present invention is a preparation containing at least one oxidizing agent and at least one polyurethane PU.

In addition, we offer in the invention, the preparations may contain antioxidants, such as ascorbic acid, thioglycolate acid or sodium sulfite, as well as komleksoobrazovateli for heavy metals, for example, ethylenediaminetetraacetate or nitriloside acid in an amount of about 0.5% mass..

In addition, the proposed invention the preparations preferably may contain other additives commonly used in the media for dyeing hair, such as higher aliphatic alcohols, preservatives, komleksoobrazovateli, solvents, particularly lower aliphatic Speer is s, for example, ethanol, propanol or isopropanol, or glycols, such as glycerol or 1,2-propylene glycol, wetting agents or emulsifiers from the classes of anionic, cationic, amphoteric or nonionic surfactants, plasticizers, vaseline, silicone oil, paraffin oil, Polysorbate and fatty acids, and substances for cosmetic care, in particular, cationic polymers or resins, lanolin derivatives, cholesterol, vitamins, Pantothenic acid and betaine. Although not required, the preparations can also contain other thickeners, such as homopolymers of acrylic acid, hydrophobically modified polyacrylic acid, vegetable gums, cellulose derivatives, starch derivatives, polysaccharides from algae or amphiphilic associate thickeners.

The above components are used in common for the respective purposes of quantities: for example, the content of the wetting agents and emulsifiers is from 0.1 to 30% wt. while the content of substances for cosmetic care is from 0.1 to 5.0 wt%. (respectively in terms of the drug).

Proposed in the invention, the preparations for hair coloring are produced preferably in the form of an aqueous or hydroalcoholic preparations, for example, thickened solutions, as well as in the form of emulsions, the remov or gels.

To use for the oxidation dyeing the above component (A) as a rule immediately before use mix containing oxidizing agent component (C), and ready-to-use preparation is applied on the fibers sufficient for coloring amount, generally from about 60 to 200 grams.

The pH of the proposed in the invention of drugs (if we are talking about non-oxidizing coloring tools based on the direct dye is in an approximate range from 5 to 10, preferably from 6 to 9.

If preparations for dyeing keratin fibers are systems composed of two or more components that are mixed prior to bringing into contact with the keratin fibers, the pH of the corresponding mixture is in the range from 6 to 12, preferably from 8 to 11, particularly preferably from 8.5 to 9.5 and above all is about 9.

PH containing the peroxide component is in the range from 1 to 4, preferably from 2 to 3. The pH of the basics for painting, that is, the component that contains the source material for dye and a color-forming component is in the range from 9 to 11 and preferably is about 10. Proper pH ready-to-use proposed in which sobienie of the drug out by mixing a specified basis, pH which is preferably installed in the alkaline range, with an oxidizing agent, the pH of which is often installed in the acidic range, by selecting the appropriate quantities of alkali in the base and acid in an oxidizing medium, and the ratio of components of the mixture.

The above polyurethane PU, suitable for the proposed in the invention may be present either in one or in both of the above components. Polyurethane PU preferably present in a peroxide component, and, consequently, also at a pH of from 1 to 4, preferably from 2 to 3.

The pH of the drug depending on its type and the required range of pH values are preferably set by means of ammonia or organic amines, such as glucamine, aminomethyl-propanol, monoethanolamine or triethanolamine, inorganic bases such as sodium hydroxide, potassium hydroxide, sodium carbonate or calcium hydroxide, or organic or inorganic acids, such as lactic acid, citric acid, acetic acid or phosphoric acid.

If the proposed invention in the preparation does not contain the original substances and oxidative dye or contains source materials for the oxidation of the dye, which can be easily oxidized Kislorodmontage, this drug can be applied directly to the keratin fibers without prior mixing with oxidizing agent. As the oxidizing means to trigger staining, you can use mainly hydrogen peroxide or products of its accession to urea, melamine or sodium borate in aqueous solution concentration of from 1 to 12 wt%. preferably from 1.5 up to 6% of the mass. The ratio of the coloring tool to oxidizing agent in the mixture of components depending on the concentration of the oxidizing means is generally located in the approximate range from 5:1 to 1:2 and preferably is 1:1, and the content of the oxidizing means in a ready-to-use preparation is preferably from about 0.5 to 8 wt%. first of all, from 1 to 4% of the mass.

Keratin fibers such as human hair) is exposed to ready-to-use painting tools at temperatures from 15°to 50 ° C for an approximate period of time of 10 to 45 minutes, preferably from 15 to 30 minutes, then washed with water and dried. Immediately after such washing (rinsing) keratin fibers (hair) optionally washed with shampoo, and then they can be subjected to additional washing is a weak organic acid, for example, Taco is as tartaric acid. In conclusion, the keratin fibers are subjected to drying.

The object of the present invention is a method of dyeing keratin fibers, especially human hair, characterized in that the implement contact proposed in the invention of the drug to be dyeing keratin fibres and dyeing keratin fibers is in the range of pH 8 to 10, and before the implementation of the specified contact component (a) and component (C) are mixed with each other and with the specified contact is implemented, if the dynamic viscosity of the mixture of the component (A) with component (b) is at least 3000 MPa·S.

Tools for hair care

The goal of cosmetic hair care is that over a long period to support growing hair in the natural state, and in case of loss of such status to the maximum extent possible to restore it. Features of healthy natural hair is smooth and shiny and nice smooth neck.

In accordance with the present invention as a means for hair care use for pre-treatment of the hair, conditioners for hair conditioners and balms), therapeutic agents for the hair, and there are medicinal drugs that leave on the hair, and therapeutic drugs the ATA, wash away from the hair, liquid hair styling products hair, such as lipstick, Bioline, lotions, hair styling, styling gels, hair gels, which gives the hair a wet look and gels, which gives the hair Shine), sprays of liquid oil products for hot hair treatment and therapeutic foam.

Well-known specialists in the usual formulation of such tools for hair care, please see pages 247-264 guide "Kosmetik and Hygiene von Kopf bis Fuβ", publisher W.Umbach, 3rd edition, Wiley-VCH, 2004, section 9.2, the text of which in full should be considered an appropriate reference. In addition to used according to the invention the polyurethanes PU means for care of hair may be present above and below the ingredients, partially identical to those used in the above proposed invention shampoos.

Depending on the scope of use of the hair care products can have the form of sprays, foams, gels, spray gels, creams, lotions or waxes.

Under the sprays for hair mean as aerosol sprays and sprays, spray sprinklers (without propellant gas). Under the pen hair meant as an aerosol foam, and foam, spray sprinklers (without propellant gas). Sprays and foam for hair preferably soda is RATM mainly or solely water-soluble or water-dispersible components.

If the compounds used in the present invention sprays and foams for the hair, are water-dispersible, these drugs can be used in aqueous microdisperse with particles, whose diameter is usually from 1 to 350 nm, preferably from 1 to 250 nm. The content of solids in such preparations is typically in the approximate range from 0.5 to 20% wt. The use of emulsifiers or surfactants to stabilize such microdisperse usually not required.

Tools containerbase

The preferred proposed in the invention means for hair care in addition to used according to the invention the polyurethanes PU contain conditioning facility.

According to the invention preferred conditioning means is shown, for example, section 4 of the International Handbook of cosmetic ingredients (International Cosmetic Ingredient Dictionary and Handbook, vol. 4, publishers R..Pepe, J.A.Wenninger, G.N.McEwen, publishing house of The Cosmetic, Toiletry, and Fragrance Association, 9th edition, 2002, keywords Hair Conditioning Agents", "Humectants, Skin-Conditioning Agents", "Skin-Conditioning Agents-Emollient", "Skin-Conditioning Agents-Humectant", "Skin-Conditioning Agents-Miscellaneous", "Skin-Conditioning Agents-Occlusive", "Skin Protectans"), and any connection called "water soluble conditioning agent" and "oil soluble conditioning agent is, specified on pages 11-13 of the European patent application EP-A 934956.

Preferred conditioning agents are, for example, listed in the above table, the compounds named according to the nomenclature INCl "polyquaternium" (primarily products from polyquaternium-1 to polyquaternium-87).

Suitable conditioning means include, for example, also polymeric Quaternary ammonium compounds, cationic cellulose derivatives, starch derivatives, derivatives of maltodextrin and derivatives of polysaccharides, as well as quaternion protein hydrolysates and quaternion silicone derivatives.

According to the invention in other preferred conditioners are derivatives of cellulose, particularly polyquaternium-10 and poly-quaterni-67 (for example, brand Ucare®Polymer, brand SoftCAT®Polymer (Dow Chemical company) and quaternion the guar derivative resin, especially guerrerocusumano chloride (for example, products Jaguar Excel®, Jaguar C-14S, Jaguar C-13S and Jaguar With 162®the company Rhodia, CAS 65497-29-2, CAS 39421-75-5).

According to the invention as a means of conditioning can preferably also be used non-ionic copolymers of n-vinylpyrrolidone with vinyl acetate (e.g., product Luviskol®VA 64 BASF), anionic copolymers of acrylates (for example, product Luviflexthe Soft BASF) and/or amphoteric copolymers based on amides, acrylates and methacrylates (for example, product Amphomer®company National Starch).

A preferred object of the present invention are hair care products in the form transparent gels that contain at least 0.1% wt., preferably at least 0.2% wt., particularly preferably at least 0.5% of the mass of electrolyte in terms of General preparation. Proposed in the invention is the use of polyurethanes PU as thickeners allows the production of stable transparent gel with a concentration of electrolytes comprising at least 0.1% wt., preferably at least 0.2% wt., particularly preferably at least 0.5% wt. but not more than 10% of the mass..preferably not more than 5 wt. -%, especially preferably not more than 1% of the mass. in terms of General preparation.

From conventional thickeners such stable transparent gels and conditioners can't refuse.

Depending on the scope of use of such gels and conditioners preferably contain other ingredients. Suitable other ingredients known in the art and are discussed in detail above.

Acidic drugs

Many cosmetic products contain active ingredients which exhibit the required action is first of all when pH, located in the acidic range. These include, for example, preparations containing alpha-hydroxycarbonate acid and beta-hydroxycarbonate acid, since such drugs in neutralized state have minimum efficiency or its complete absence.

Using conventional thickeners can not sagemath similar drugs such a way that they remained stable for a long time, or such thickening is possible only with great difficulty.

Thus, an object of the present invention are cosmetic and dermatological preparations which are in addition used according to the invention polyurethane PU contain at least one active substance, manifesting its inherent cosmetic and/or dermatological efficiency at acidic pH, i.e. pH in the range from 1 to 7.

Preferred active substances of this type are alpha hydroxy acids and beta hydroxy acids. Preferred are such preparations the pH of which is in the range from 3 to 6, particularly preferably in the range from 4 to 5.5.

For skin treatment with typical age-related changes, keratinization, due to exposure to light damage, and acne, dermatology increasingly IP is result methods of surface peeling and peeling the average depth. Superficial peels are most commonly performed by using an alpha-hydroxycarbonic acids, and therefore it is also called peeling fruit acids. The most important substance with a high payoff in the relevant dermatological practice is glycolic acid.

Alpha-hydroxycarbonate acid have on the skin epidermal and dermal exposure. They affect the cohesion of corneocytes, i.e. dissolve old or dead cellular material and thinner epidermal stratum corneum. Simultaneous intensification of the process of cell renewal causes thickening under the Horny layer of the epidermis. Other epidermal effect is enhanced synthesis of glycosaminoglycans and collagen, and the resulting improvement in skin hydration. Important dermal effect of alpha-hydroxyacids, confirmed at the present time primarily for glycolic acid is the formation of new elastic and collagen fibers. Glycolic acid and other alpha hydroxy acids are shown primarily for ichthyosis, hyperkeratosis treatment, acne and warts. Therapeutic applications are appropriate dilute (5 to 15%) and high concentration (above 50%) drugs. Treatment of dilute solutions and gels logotipos.net themselves past the corresponding instructing patients while the processing of highly concentrated preparations should be made by the physician. For such immediate peeling fruit acids in most cases use the solutions of glycolic acid, the concentration of which at least processing can be increased to 70%.

One of the embodiments of the invention involves the use of drugs for peeling, containing at least one of the above polyurethane and at least one alpha-hydroxycarbonyl acid.

According to the invention the alpha-hydroxy acid is preferably selected from the group including lactic acid, glycolic acid, malic acid, Castronovo acid, tartaric acid, glucuronic acid, pyruvic acid, 2-hydroxyisobutyryl acid, 3-hydroxy-somaclonal acid, citric acid, galacturonic acid, almond acid, mucus acid, beta-phenylalanyl acid, beta-phenylpyruvic acid, some saccharine acid, alpha-hydroxybutiric acid, alpha-hydroxyisobutyryl acid, alpha-hydroxy-isocaproate acid, alpha-hydroxyisovaleric acid, Atro-lactic acid, galactagogue acid, Pantothenic acid, glyceric acid, solomonow acid, dihydroxyaluminum acid, di-hydroximino acid, dihydroxyfumaric acids and benzylmorphine acid, especially preferred are lactic acid and glycolic acid. In one of the embodiments of the invention use a combination of the two acids. Suitable beta-hydroxy acids are, for example, salicylic acid, and D-carnitine and L-carnitine.

In addition, according to the invention can be used esters of alpha-hydroxy acids, a feature of which is that they are slower allocate available alpha-hydroxy acid inside the skin. Such esters primarily include commercially available products sold under the trade names of Cosmacol ETL®(dialkylated of 14-15 carbon atoms in the alkyl), Cosmacol ECL®(trialkylsilyl of 14-15 carbon atoms in the alkyl), Cosmacol ELI®(al-killacat 12-13 carbon atoms in the alkyl), Cosmacol FOI®(alkylate-neat 12-13 carbon atoms in the alkyl), Cosmacol EMI®(dialkylated 12-13 carbon atoms in the alkyl), Cosmacol ECI®(trialkylsilyl 12-13 carbon atoms in the alkyl and Cosmacol ETI®(dialkylated 12-13 carbon atoms in the alkyl). These esters individually or in a mixture injected in the preparations in quantities of from 2 to 15%, preferably from 4 to 10% based on the total weight of the preparation.

Preparations for oral hygiene and dental care

Another variant implementation of izobreteny what concerns the preparations for the care of mouth and teeth and cleaning, containing at least one used according to the invention polyurethane PU. Means for cleaning the teeth have different final forms and primarily designed to cleanse the surface of teeth and prevention of diseases of the teeth and gums. Such tools typically include a combination of polishing materials, humectants, surfactants, binders, fragrances, containing fluorides active substances, as well as antimicrobial active substances. In addition to tooth powders, which are due to high abrasively currently play only a minor role, means for brushing your teeth put on the market primarily in the form of pastes, creams and translucent or transparent gels. In recent years, the increasing importance liquid dental creams and formulations for oral rinsing.

In accordance with the present invention means to care for your mouth and teeth and to means for cleaning the mouth and teeth are appropriate powders, pastes, liquid creams and gels. Preferred are toothpastes and liquid for cleaning the teeth. This means to clean and care for your mouth and teeth may be, for example, in the form of toothpastes, liquid dental creams, tooth powders or compositions for rinsing the mouth. what, however, preferred are more or less fluid or plastic toothpaste, teeth which are usually cleaned with a toothbrush.

In a preferred embodiment of the invention the preparations for the care of teeth contain nanoparticles of calcium salts, especially nanoparticles of hydroxyapatite, fluorapatite and/or calcium fluoride. Such nanoparticles and obtaining them are described, for example, in German patent DE 102006009780 A1, European patent EP 934 449, European patent application EP-1023035, European patent EP 1139995 and above all in the international application WO 03/000588.

As other ingredients these drugs if necessary, contain water-soluble surfactant and/or water-soluble polymeric protective colloids. The content of at least one water-soluble surfactant and/or at least one water-soluble polymeric protective colloid is in the range from 0.01 to 15 wt. -%, preferably from 0.1 to 10 wt%. and especially from 0.5 to 7.5% of the mass. in terms of preparation.

Suitable anionic surfactants described in paragraphs [0052] and [0053]suitable zwitterionic surfactants in paragraph [0054]suitable amphoteric surfactants in paragraph [0055]suitable nonionic surfactants in paragraphs [0056] to [0061] suitable cationic surfactants in paragraphs [0062] to [0065] of the description of the German DE 102006009780 A1, the text in full should be considered an appropriate reference.

Suitable water-soluble polymeric protective colloids is given in paragraphs [0066] to [0099] the description of the German patent DE 102006009780 A1, the text of which in full should be considered an appropriate reference.

In addition, the proposed in the invention, the preparations may contain protein components, such as protein hydrolysates. Suitable according to the invention the protein components described in paragraphs [0115] on [0123] the description of the German patent DE 102006009780 A1, the text of which in full should be considered an appropriate reference.

Proposed in the invention means for the care of mouth and teeth and cleaning in addition to the above ingredients may additionally contain other ingredients to cleanse the oral cavity, means to care for the oral cavity, means for cleaning the teeth and/or money to care for teeth. Preferred additional ingredients are antimicrobial agents as preservatives or active substances against the formation of plaque, active substances against caries active substances against the formation of Tartar, polishing materials, the basis for tooth powder, moisturizing agents, additional controls consistency, substance reduced the I sensitivity of the teeth, wound healing and anti-inflammatory agents, agents to improve the capacity of mineralization, aromatic oils, sweeteners, solvents, girotropnye soljubilizatory, pigments such as titanium dioxide, colorants, buffering agents, vitamins, minerals and bioactive glass. Under the existing substances include protoceratidae lactic acid bacteria, which prevent the deposition of harmful bacteria on the tooth surface, and thus prevent their damage. Preferred other ingredients listed in paragraphs [0132] on [0182] description German patent DE 102006009780 A1, the text of which in full should be considered an appropriate reference.

Preparations for the care of mouth and teeth and cleaning, containing used according to the invention, the polyurethanes PU, differ in that their viscosity (consistency) can be improved and a long time to maintain in the presence of electrolytes and/or pigments, and also in the presence of fluoride.

Drugs for hair removal

Another variant embodiment of the invention relates to containing used according to the invention polyurethane PU drugs for hair removal. Graduation forms of drugs for hair removal are primarily depilarsi creams, depilarsi lotions and deeply the existing foam. The mechanism of action of these drugs is based on what is happening in the alkaline pH range, the cleavage of peptide bonds and disulfide bonds of the keratin of the hair restoring means, which is accompanied by a complete separation of the hair from the skin. The most important means of epilation are thioglycolate acid and tomalachka acid. Using conventional thickeners is not possible to form a sufficiently stable formulations based on thioglycolic, thio-lactic acid and other basic means of hair removal in the desired alkaline pH range. So, for example, xanthan gum although characterized by the necessary thickening action in the specified pH range, however, zahodenie her medications have unwanted sticky consistency. Drugs, zahodenie by conventional acrylate thickeners, do not have a stable consistency.

In contrast, the use of polyurethanes PU as thickeners typical drugs for hair removal can provide them with a stable and cosmetically acceptable consistency.

Drugs for long-term hair styling

Another variant embodiment of the invention relates to containing used according to the invention polyurethane PU drugs intended for long-term hair styling. The classical technique of domestic the long hair styling is based on the fact, at the first stage with a tool that contains regenerating the active substance (deforming tools), open the disulphide bonds of the keratin of the hair, then the hair to give a desired shape, and then re-connect the disulfide bonds, using the means (latch), which contains oxidizing active ingredient.

For drugs intended for long-term hair styling, characterized by high concentrations of electrolytes, the presence of oxidizing or recreational environments and sharp fluctuations in pH. Conventional thickeners are not able to provide a thickened consistency with the necessary stability. The use of polyurethanes PU can solve this problem.

As regenerating active ingredients in the drugs for long-term hair styling primarily use sulfites, thioglycolic acid, timelocal acid, 3-mercaptopropionic acid esters mercaptocarboxylic acid and cysteine. The pH of these funds to establish or acid (sulfite, bisulfite and esters mercaptocarboxylic acid)or alkaline (alkali metal salts or ammonium and mercaptocarboxylic acid) range. In the case of a deforming means with a pH that is installed in the alkaline range, the desired alkali is te provide primarily by adding ammonia, organic amines and carbonates or bicarbonates of ammonium or alkali metals. As the clamps are primarily used liquid containing hydrogen peroxide or bromates.

Proposed in the invention of the drug for long-term hair styling contains rejuvenating keratin compounds in ordinary hair styling quantities: for example, the content of ammonium salts thioglycolates or timelocal acid or cysteine in the specified drug is in the range from 6 to 12% of the mass. PH alkaline deforming means in the General case is in the range from 7 to 10, and the regulation of pH is preferably realized by means of ammonia, monoethanolamine, ammonium carbonate or ammonium hydrogen carbonate.

To establish the pH of the drug in the acidic range (for example, from 6.5 to 6.9) use esters mercaptocarboxylic acids, such as glycol or glycerol ether monotis-lilleboe acids, however, are preferred mercaptoacetate or amides of 2-mercaptopropionic acid, used at a concentration of from 2 to 14 wt%. in terms of preparation, as well as salts of sulfurous acid, for example, sodium sulfite, ammonium sulfite or sulfite of monoethanolamine (calculated as S02), used at a concentration of from 3 to 8% of the mass. in terms of the and the drug. The connection is preferably used to restore the keratin of the hair, is a salt or derivative mercaptocarboxylic acid. Reparative keratin compound is especially preferably selected from the group comprising thioglycolic acid, cysteine, timelocal acid or their salts.

In order to enhance the effectiveness of the drug for long-term hair styling you can add contributing to the swelling and penetration substances, such as urea, polyhydric alcohols, ethers, melamine, thiocyanates of alkali metals or ammonium, isopropanol, imidazolidin-2-it, 2-pyrrolidone and 1-methyl-2-pyrrolidone, the approximate concentration of which ranges from 0.5 to 50 wt%. preferably from 2 to 30% of the mass in terms of preparation.

In a preferred embodiment of the invention the preparation additionally contains a compound that restores the hair keratin disulfide, primarily dithioglycolic. Preferred used, the number of such connections is from 2 to 20% of the mass. preferably from 3 to 10% of the mass. accordingly, in terms of the drug, and mass ratio of restoring the hair's keratin compound and the disulfide is preferably in the range from 2:1 to 1:2, especially from 2:1 to 1:1.

Proposed in the invention, the preparations for algorem is authorized styling hair can be in the form of an aqueous solution or emulsion, and thickened discharge the form of a water-based, primarily in the form of a cream, gel or paste.

Proposed in the invention of drugs for long-term hair styling, obviously, can contain any known additives commonly used in such preparations, in particular, other thickeners, such as kaolin, bentonite, fatty acids, higher aliphatic alcohols, starch, polyacrylic acid, cellulose derivatives, alginates, vaseline or paraffin oil, wetting agents or emulsifiers from the group of anionic, cationic, amphoteric or nonionic surface-active substances, for example, sulfates of aliphatic alcohols, sulfonic ethers of aliphatic alcohols, alkyl sulphonates, alkyl-bansilalpet, Quaternary ammonium salts, alkylbetaine, ethoxylated aliphatic alcohols, ethoxylated ALKYLPHENOLS, alkanolamide fatty acids or ethoxylated esters of fatty acids, means to impart opacity, such as esters of polyethylene glycol or alcohols, such as ethanol, propanol, isopropanol or glycerol, girotropnye soljubilizatory, stabilizers, buffer substances, aromatic oils, hair conditioners, as well as components resources for hair care, such as cationic polymers, lanolin derivatives,cholesterol, Pantothenic acid, creatine or betaine.

Suitable cationic polymers described in paragraphs [0036] to [0044] the description of the German patent DE 102004054055 A1, the text of which in full should be considered an appropriate reference. Other suitable for hair care cationic compounds that may be present in the proposed invention the drugs are cation-modified derivatives of proteins or cation-modified protein hydrolysates described in paragraphs [0045] and [0046] a description of German patent DE 102004054055 A1, the text of which in full should be considered an appropriate reference.

Used according to the invention, the polyurethanes PU differ also in that they allow for the reversible reduction of viscosity proposed in the invention of drugs at elevated temperatures. Due to this, at elevated temperatures simplified packaging of cooked prepares and increases its speed.

The following examples serve for a more detailed explanation of the present invention and do not limit its scope.

Examples

In the absence of specific instructions, all quantitative data are given in weight percents (wt%).

Determination of dynamic viscosity

Dynamic viscosity used according to the invention the polyurethanes PU esmeraude 23°C for the corresponding aqueous dispersions with 10% concentration. In the examples below, the dynamic viscosity polyurethanes PU is always determined at shear rate 100 1/s and 350 1/s Specified speed shift allows us to come to an unambiguous conclusion about the behavior of polyurethanes PU in aqueous dispersions, that is how they are strukturnovyazkikh or Newtonian thickeners.

To determine the dynamic viscosity according to DIN 53019 using:

- rotary viscometer Physica Rheolab MCI Portable company Anton, Raag,

cylinder measuring system Z4 with a diameter of 14 mm (according to DIN).

Example of synthesis 1. Obtaining polyurethanes PU

17,75 kg linear polyethylene glycol with srednetsenovoj molecular weight of 6000 g/mol (e.g., product Pluriol®E BASF SE) was dissolved under nitrogen atmosphere in 23,50 kg of xylene. After heating the resulting solution to a temperature of about 140°C. xylene drove in an amount such that the water content in the prepared subsequently the reaction mixture did not exceed about 140 parts per million

Then the polymer solution was cooled to 50°C and mixed with a solution of 13.1 g of acetic acid in 500 ml of xylene used as a buffer for previously entered in the glycol certain amount of potassium acetate. Polymerization was initiated by adding 37,28 g neodecanoate zinc, dissolved in a mixture of aliphatic hydrocarbons with xylene and 870,0 g dissolved in xylene of hexamethylenediisocyanate and continued at 50°C. until the residual isocyanate in the reaction mixture, average of 0.27% of the mass.

After this was added dissolved in xylene mixture containing 1.42 kg nonionic ethoxylated aliphatic alcohol with an average degree of amoxilonline 10, obtained from the isomeric saturated alcohol with 13 carbon atoms (for example, product Lutensol®TO BASF SE), and 1.64 kg of a mixture of non-ionic ethoxylated aliphatic alcohols with an average degree of amoxilonline 11 obtained from a mixture of saturated alcohols with 16/18 carbon atoms (for example, product Lutensol®AT 11 BASF SE). The reaction mixture was heated at 50°C until the isocyanate content was reduced to 0% of the mass. The xylene was removed to a residual content of less than 500 parts per million by subsequent distillation in a vacuum at elevated temperature.

The resulting product PO is a mixture of linear polyurethanes with terminal branched and/or unbranched sections (T). The ratio of the molecular weight of the hydrophilic segment (S) to the molecular weight of the hydrophilic segment (P) in the polyurethanes PU in typical cases is 1:12,4 (if area (S) consist of 11 ethylenoxide residues), respectively, 1:13,6 (if area (S) consist of 10 ethylenoxide residues).

The molar ratio plots (B) to sections (D) is 1:1,75.

Product PU was dispersible in 86,73 kg of water, and poluchenuiya was cooled to room temperature (25°C). The mixture of polymers PU (MP 17600 g/mol, Mw 30500 g/mol) was in the form of an aqueous dispersion with a solids content of 20.5% of the mass. The viscosity of the aqueous dispersion of politicalisation PU a 10% concentration. at 23°C was 7700 MPa·s (shear rate 100 1/s), respectively 5900 MPa·s (shear rate 350 1/s), which corresponds to a weakly pronounced structures-novascope behavior.

Example of synthesis 2. Obtaining polyurethanes PU

17,75 kg linear polyethylene glycol with srednetsenovoj molecular weight of 6000 g/mol (e.g., product Pluriol®E BASF SE) was dissolved under nitrogen atmosphere in 23,50 kg of xylene. After heating the resulting solution to a temperature of about 140°C. xylene drove in an amount such that the water content in the prepared subsequently the reaction mixture did not exceed about 250 parts per million

Then the polymer solution was cooled to 50°C and mixed with a solution of 13.1 g of acetic acid in 500 ml of xylene used as a buffer for previously entered in the glycol certain amount of potassium acetate.

Polymerization was initiated by adding 37,28 g neodecanoate zinc, dissolved in a mixture of aliphatic hydrocarbons with xylene, and 870,0 g dissolved in xylene of hexamethylenediisocyanate and continued at 50°C. until the residual isocyanate in the reaction mixture comprising 0,29% of the mass.

After this was added dissolved in xylene mixture containing 0,95 kg nonionic ethoxylated aliphatic alcohol with an average degree of amoxilonline 10, obtained from the isomeric saturated alcohol with 13 carbon atoms (for example, product Lutensol®TO BASF SE), and 2,19 kg of a mixture of non-ionic ethoxylated aliphatic alcohols with an average degree of amoxilonline 11 obtained from a mixture of saturated alcohols with 16/18 carbon atoms (for example, product Lutensol®AT BASF SE). The reaction mixture was heated at 50°C until the isocyanate content was reduced to 0% of the mass.

The xylene was removed to a residual content of less than 500 parts per million by subsequent distillation in a vacuum at elevated temperature.

The resulting product PO is a mixture of linear polyurethanes with terminal branched and/or unbranched sections (T). The ratio of the molecular weight of the hydrophilic segment (S) to the molecular weight of the hydrophilic segment (P) in the polyurethanes PU in typical cases is 1:12,4 (if area (S) consist of 11 ethylenoxide residues), respectively, 1:13,6 (if area (S) consist of 10 ethylenoxide residues).

The molar ratio plots (B) to sections (D) is 1:1,75.

Product PU was dispersible in 87,02 kg of water, and the resulting dispersion was cooled the to room temperature (25°C). The mixture of polymers PU (Mn16700 g/mol, Mw29500 g/mol) was in the form of an aqueous dispersion with a solids content of 20.0% of the mass. The viscosity of the aqueous dispersion of politicalisation PU a 10% concentration. at 23°C was 26200 MPa·s (shear rate 100 1/s), respectively 12800 MPa·s (shear rate 350 1/s, which is expressed strukturnovyazkikh behavior.

Example of synthesis 3.

Obtaining polyurethanes PU

120,00 grams of linear polyethylene glycol with srednetsenovoj molecular weight of 6000 g/mol (e.g., product Pluriol®E BASF SE) was dissolved under nitrogen atmosphere in 467,00 g of xylene. After heating the resulting solution to a temperature of about 140°C. xylene drove in an amount such that the water content in the prepared subsequently, the reaction mixture was less than 300 parts per million

Then the polymer solution was cooled to 50°C. the Polymerization was initiated by adding 42 mg neodecanoate zinc, dissolved in a mixture of aliphatic hydrocarbons and 5,88 g dissolved in xylene of hexamethylenediisocyanate and continued at 50°C. until the residual isocyanate in the reaction mixture of 0.25% of the mass.

After this was added 19,20 g dissolved in xylene nonionic ethoxylated aliphatic alcohol with an average degree of amoxilonline 10 received the C isomeric saturated alcohol with 13 carbon atoms (for example, product Lutensol®TO BASF SE), and the reaction mixture was heated at 50°C until the isocyanate content was reduced to 0% of the mass. The xylene was removed to a residual content of less than 500 parts per million by subsequent distillation in a vacuum at elevated temperature.

The resulting product PO is a mixture of linear polyurethanes with terminal branching plots (T). A typical ratio of molecular weight of the hydrophilic segment (S) to the molecular weight of the hydrophilic segment (P) in the polyurethanes PU is 1:13,6 (if area (S) consist of 10 ethylenoxide residues).

The molar ratio plots (B) to sections (D) is 1:1,75.

Product PU was dispersible in 580,3 g of water, and the resulting dispersion was cooled to room temperature (25°C). The mixture of polymers PU (MP 27200 g/mol, Mw 51900 g/mol) was in the form of an aqueous dispersion with a solids content of 20.0% of the mass. The viscosity of the aqueous dispersion of politicalisation PU concentration of 10 wt% at 23°C was 680 MPa·s (shear rate 100 1/s), respectively 640 MPa·s (shear rate 350 1/s), which corresponds to Newtonian behavior.

Example of synthesis 4. Obtaining polyurethanes PU

17,75 kg linear polyethylene glycol with srednetsenovoj molecular weight of 6000 g/mol (e.g., product Pluriol®E BASF SE) was dissolved in Atmos is ore of nitrogen in 23,50 kg of xylene. After heating the resulting solution to a temperature of about 140°C. xylene drove in an amount such that the water content in the prepared subsequently the reaction mixture did not exceed about 120 parts per million

Then the polymer solution was cooled to 50°C and mixed with a solution of 13.1 g of acetic acid in 500 ml of xylene used as a buffer for previously entered in the glycol certain amount of potassium acetate.

Polymerization was initiated by adding 37,28 g neodecanoate zinc, dissolved in a mixture of aliphatic hydrocarbons with xylene, and 870,0 g dissolved in xylene of hexamethylenediisocyanate and continued at 50°C. until the residual isocyanate in the reaction mixture, comprising 0,26% of the mass.

After this was added 2,84 kg dissolved in xylene nonionic ethoxylated aliphatic alcohol with an average degree of amoxilonline 10, obtained from the isomeric saturated alcohol with 13 carbon atoms (for example, product Lutensol®TO BASF SE), and the reaction mixture was heated at 50°C until the isocyanate content was reduced to 0% of the mass. The xylene was removed to a residual content of less than 500 parts per million by subsequent distillation in a vacuum at elevated temperature.

The resulting product PO is a mixture of linear polyurethanes the end of the branched sections (T). A typical ratio of molecular weight of the hydrophilic segment (S) to the molecular weight of the hydrophilic segment (P) in the polyurethanes PU is 1:13,6 (if area (S) consist of 10 ethylenoxide residues).

The molar ratio plots (B) to sections (D) is 1:1,75.

Product PU was dispersible in 85,84 kg of water, and the resulting dispersion was cooled to room temperature (25°C). The mixture of polymers PU (Mn19200 g/mol, Mw30800 g/mol) was in the form of an aqueous dispersion with a solids content of 18.1% of the mass. The viscosity of the aqueous dispersion of politicalisation PU a 10% concentration. at 23°C was 600 MPa·s (shear rate 100 1/s), respectively 570 MPa·s (shear rate 350 1/s), which corresponds to the behavior of Newtonian thickener.

The synthesis example 5. Obtaining polyurethanes PU

240,00 grams of linear polyethylene glycol with srednetsenovoj molecular weight of 6000 g/mol (e.g., product Pluriol®E BASF SE) was dissolved under nitrogen atmosphere in 934,00 g of xylene. After heating the resulting solution to a temperature of about 140°C. xylene drove in an amount such that the water content in the prepared subsequently, the reaction mixture was less than 300 parts per million.

Then the polymer solution was cooled to 50°C. the Polymerization was initiated by adding 84 mg dissolved in aliphatic the ski hydrocarbons of neodecanoate zinc, and 11,76 g dissolved in xylene of hexamethylenediisocyanate and continued at 50°C. until the residual isocyanate in the reaction mixture, amounting to 0.22% of the mass.

After this was added 20,70 g dissolved in xylene nonionic ethoxylated aliphatic alcohol with an average degree of amoxilonline 3, obtained from a saturated alcohol with 13 carbon atoms (for example, product Lutensol®A BASF SE), and the reaction mixture was heated at 50°C until the isocyanate content was reduced to 0% of the mass. The xylene was removed by subsequent distillation in a vacuum at an elevated temperature to a residual content of less than 500 parts per million, and the residue was dispersible in 1089,8 g of water.

A typical ratio of molecular weight of the hydrophilic segment (S) to the molecular weight of the hydrophilic segment (P) in the polyurethanes PU is 1:45,5 (if area (S) consist of three ethylenoxide residues).

The molar ratio plots (B) to sections (D) is 1:1,75.

Cooled to room temperature (25°C) polymers PU (Mn21300 g/mol, Mw36300 g/mol) was in the form of an aqueous dispersion with a solids content of 20.1% of the mass. The viscosity of the aqueous dispersion of politicalisation PU a 10% concentration. at 23°C was 10900 MPa·s (shear rate 100 1/s), respectively 9200 MPa·s (the speed shift is 350 1/s), which corresponds to weakly expressed structurally viscous behavior.

Example of synthesis 6. Obtaining polyurethanes PU

180,00 grams of linear polyethylene glycol with srednetsenovoj molecular weight of 6000 g/mol (e.g., product Pluriol®E BASF SE) was dissolved under nitrogen atmosphere in 180,00 g of acetone. After heating the solution to form phlegmy (internal temperature of about 56°C) was continuously added 1362,4 g of acetone and simultaneously drove him away in the total number 1362,4 gulgazarian subsequent reaction mixture did not exceed about 240 parts per million.

Then the polymer solution was cooled to 50°C. the Polymerization was initiated by adding 189 mg dissolved in aliphatic hydrocarbon neodecanoate zinc and 8,82 g dissolved in acetone of hexamethylenediisocyanate and continued at 50°C. until the residual isocyanate in the reaction mixture, amounting to 0.33% of the mass.

After this was added 15,53 g dissolved in acetone nonionic ethoxylated aliphatic alcohol with an average degree of amoxilonline 3, obtained from a saturated alcohol with 13 carbon atoms (for example, product Lutensol®A BASF SE), and the reaction mixture was heated at 50°C until the isocyanate content was reduced to 0% of the mass. The acetone was removed by further distillation in vacuum at elevated is the first temperature to a residual content of less than 500 parts per million, and the residue was dispersible in 817,4 g of water.

A typical ratio of molecular weight of the hydrophilic segment (S) to the molecular weight of the hydrophilic segment (P) in the polyurethanes PU is 1:45,5 (if area (S) consist of three ethylenoxide residues).

The molar ratio plots (B) to sections (D) is 1:1,75.

Cooled to room temperature (25°C) polymers PU (Mn24900 g/mol, Mw40000 g/mol) was in the form of an aqueous dispersion with a solids content of 19.6 wt%. The viscosity of the water dispersion of poly-epipaleolithic PU a 10% concentration. at 23°C was 80800 MPa·s (shear rate 100 1/s), respectively 7800 MPa·s (shear rate 350 1/s, which is weakly expressed structurally viscous behavior.

The synthesis example 7. Obtaining polyurethanes PU

120,00 grams of linear polyethylene glycol with srednetsenovoj molecular weight of 6000 g/mol (e.g., product Pluriol®E BASF SE) was dissolved under nitrogen atmosphere in 467,00 g of xylene. After heating the resulting solution to a temperature of about 140°C. xylene drove in an amount such that the water content in the prepared subsequently the reaction mixture did not exceed about 120 parts per million.

Then the polymer solution was cooled to 50°C and mixed with a solution of 107 mg of acetic acid in 5 ml of xylene used as the e buffer for previously entered in the glycol certain amount of potassium acetate. Polymerization was initiated by adding 252 mg neodecanoate zinc, dissolved in a mixture of aliphatic hydrocarbons with xylene, and 5,88 g dissolved in xylene of hexamethylenediisocyanate and continued at 50°C. until the residual isocyanate in the reaction mixture of 0.25% of the mass.

After this was added 22,20 g dissolved in xylene mixtures of non-ionic ethoxylated aliphatic alcohols with an average degree of amoxilonline 11 obtained from a mixture of saturated alcohols with 16/18 carbon atoms (for example, product Lutensol®AT BASF SE). The reaction mixture was heated at 50°C until the isocyanate content was reduced to 0% of the mass. The xylene was removed by subsequent distillation in a vacuum at an elevated temperature to a residual content of less than 500 parts per million.

The resulting product PO is a mixture of linear polyurethanes with terminal unbranched sections (T). A typical ratio of molecular weight of the hydrophilic segment (S) to the molecular weight of the hydrophilic segment (P) in the polyurethanes PU is 1:12,4 (if area (S) consist of 11 ethylenoxide residues).

The molar ratio plots (B) to sections (D) is 1:1,75.

Product PU was dispersible in 592,3 g of water, and the resulting dispersion was cooled to room temperature (25°C). The polymer mixture P Is .7 (MP 18700 g/mol, Mw 30900 g/mol) was in the form of an aqueous dispersion with a solids content of 20.4% of the mass. The viscosity of the aqueous dispersion of politicalisation PU a 10% concentration. at 23°C was 35500 MPa·s (shear rate 100 1/s), respectively 14500 MPa·s (shear rate 350 1/s, which is strongly expressed strukturnovyazkikh behavior.

Example 8 synthesis. Obtaining polyurethanes PU

180,00 g linear polyethylene glycol with srednetsenovoj molecular weight of 9000 g/mol (e.g., product Pluriol®E BASF SE) was dissolved under nitrogen atmosphere in 467,00 g of xylene. After heating the resulting solution to a temperature of about 140°C. xylene drove in an amount such that the water content in the prepared subsequently the reaction mixture did not exceed about 70 parts per million.

Then the polymer solution was cooled to 50°C and mixed with a solution of 208 mg of acetic acid in 5 ml of xylene used as a buffer for previously entered in the glycol certain amount of potassium acetate. Polymerization was initiated by adding 378 mg neodecanoate zinc, dissolved in a mixture of aliphatic hydrocarbons with xylene, and 5,88 g dissolved in xylene of hexamethylene-socyanate and continued at 50°C. until the residual isocyanate in the reaction mixture, amounting to 0.27% of the mass.

After this the th added 10,20 g dissolved in kilalanin ethoxylated isomeric aliphatic alcohol with an average degree of amoxilonline 3, obtained from the isomeric saturated alcohol with 13 carbon atoms (for example, product Lutensol®TO BASF SE), and the reaction mixture was heated at 50°C until the isocyanate content was reduced to 0% of the mass. The xylene was removed by further distillation under vacuum at elevated temperature to a residual content of less than 500 parts per million.

The resulting product PO is a mixture of linear polyurethanes with terminal branching plots (T). A typical ratio of molecular weight of the hydrophilic segment (S) to the molecular weight of the hydrophilic segment (P) in the polyurethanes PU is 1:68,2 (if area (S) consist of three ethylenoxide residues).

The molar ratio plots (B) to sections (D) is 1:1,75.

Product PU was dispersible in 784,3 g of water, and the resulting dispersion was cooled to room temperature (25°C). The mixture of polymers PU (Mn27300 g/mol, Mw46500 g/mol) was in the form of an aqueous dispersion with a solids content of 20.2% of the mass. The viscosity of the aqueous dispersion of politicalisation PU a 10% concentration. at 23°C was 1060 MPa·s (shear rate 100 1/s, respectively 350 1/s, which is expressed Newtonian behavior.

Example 9 synthesis. Obtaining polyurethanes PU

180,00 grams of linear polyethylene glycol with srednetsenovoj molecular what assay 9000 g/mol (e.g., product Pluriol®E BASF SE) was dissolved under nitrogen atmosphere in 467,00 g of xylene. After heating the resulting solution to a temperature of about 140°C. xylene drove in an amount such that the water content in the prepared subsequently the reaction mixture did not exceed about 70 parts per million.

Then the polymer solution was cooled to 50°C and mixed with a solution of 208 mg of acetic acid in 5 ml of xylene used as a buffer for previously entered in the glycol certain amount of potassium acetate. Polymerization was initiated by adding 378 mg neodecanoate zinc, dissolved in a mixture of aliphatic hydrocarbons with xylene, and 5,88 g dissolved in xylene of hexamethylenediisocyanate and continued at 50°C. until the residual isocyanate in the reaction mixture, amounting to 0.28% of the mass.

After this was added dissolved in xylene mixture containing 5.10 g of nonionic ethoxylated isomeric aliphatic alcohol with an average degree of amoxilonline 3, obtained from the isomeric saturated alcohol with 13 carbon atoms (for example, product Lutensol®TOZ BASF SE), and 11,10 g of a mixture of non-ionic ethoxylated aliphatic alcohols with an average degree of amoxilonline 11 obtained from a mixture of saturated alcohols with 16/18 carbon atoms (for example, product Lutensol®AT Phi is we BASF SE). The reaction mixture was heated at 50°C until the isocyanate content was reduced to 0% of the mass. The xylene was removed to a residual content of less than 500 parts per million by subsequent distillation in a vacuum at elevated temperature.

The resulting product PO is a mixture of linear polyurethanes with terminal branched and/or unbranched sections (T). The ratio of the molecular weight of the hydrophilic segment (S) to the molecular weight of the hydrophilic segment (P) in the polyurethanes PU in typical cases is 1:12,4 (if area (S) consist of 11 ethylenoxide residues), respectively, 1:68,2 (if area (S) consist of three ethylenoxide residues).

The molar ratio plots (B) to sections (D) is 1:1,75.

Product PU was dispersible in 764,0 g of water, and the resulting dispersion was cooled to room temperature (25°C). The mixture of polymers PU (Mn25000 g/mol, Mw45500 g/mol) was in the form of an aqueous dispersion with a solids content of 20.8% of the mass. The viscosity of the aqueous dispersion of politicalisation PU a 10% concentration. at 23°C was 7500 MPa·s (shear rate 100 1/s), respectively 4500 MPa·s (shear rate 350 1/s), which corresponds to a strongly pronounced structure tarnawatka behavior.

Example 10 synthesis. Obtaining polyurethanes PU

120,00 g linear polietilen ikola with srednetsenovoj molecular weight of 1500 g/mol (e.g., product Pluriol®E BASF SE) was dissolved under nitrogen atmosphere in 467,00 g of xylene. After heating the resulting solution to a temperature of about 140°C. xylene drove in an amount such that the water content in the prepared subsequently the reaction mixture did not exceed about 110 parts per million.

Then the polymer solution was cooled to 50°C and mixed with a solution of 90 mg of acetic acid in 5 ml of xylene used as a buffer for previously entered in the glycol certain amount of potassium acetate. Polymerization was initiated by adding 252 mg neodecanoate zinc, dissolved in a mixture of aliphatic hydrocarbons with xylene, and 15,72 g dissolved in xylene of hexamethylenediisocyanate and continued at 50°C. until the residual isocyanate in the reaction mixture, comprising 0,29% of the mass.

After this was added 17,41 g dissolved in xylene nonionic ethoxylated aliphatic alcohol with an average degree of amoxilonline 10, obtained from the isomeric saturated alcohol with 13 carbon atoms (for example, product Lutensol®TO BASF SE), and the reaction mixture was heated at 50°C until the isocyanate content was reduced to 0% of the mass. The xylene was removed by subsequent distillation in a vacuum at an elevated temperature to a residual content of less than 500 parts per million.

The resulting product PO is a mixture of linear polyurethanes with terminal branching plots (T). A typical ratio of molecular weight of the hydrophilic segment (S) to the molecular weight of the hydrophilic segment (P) in the polyurethanes PUU is 1:13,6 (if area (S) consist of 10 ethylenoxide residues).

The molar ratio plots (B) to sections (D) is 1:1,17.

Product PU was dispersible in 612,5 g of water, and the resulting dispersion was cooled to room temperature (25°C). The mixture of polymers PU (Mn18600 g/mol, Mw34900 g/mol) was in the form of an aqueous dispersion with a solids content of 20.1% of the mass. The viscosity of the aqueous dispersion of politicalisation PU a 10% concentration. at 23°C was 165 MPa·s (shear rate 100 1/s, respectively 350 1/s, which is expressed Newtonian behavior.

Example 11 synthesis. Obtaining polyurethanes PU

90,00 grams of linear polyethylene glycol with srednetsenovoj molecular weight of 1500 g/mol (e.g., product Pluriol®E BASF SE) was dissolved under nitrogen atmosphere in 467,00 g of xylene. After heating the resulting solution to a temperature of about 140°C. xylene drove in an amount such that the water content in the prepared subsequently the reaction mixture did not exceed about 80 parts per million.

Then the polymer Rast is the PR was cooled to 50°C and mixed with a solution of 68 mg of acetic acid in 5 ml of xylene, used as a buffer for previously entered in the glycol certain amount of potassium acetate. Polymerization was initiated by adding 189 mg neodecanoate zinc, dissolved in a mixture of aliphatic hydrocarbons with xylene, and 17,64 g dissolved in xylene of hexamethylenediisocyanate and continued at 50°C. until the residual isocyanate in the reaction mixture, amounting to 0.97% of the mass.

After this was added to 99.00 g dissolved in xylene nonionic, ethoxy-profiled aliphatic alcohol with an average degree of amoxilonline 20, obtained from the isomeric saturated alcohol with 13 carbon atoms (for example, product Lutensol®TO BASF SE). The reaction mixture was heated at 50°C until the isocyanate content was reduced to 0% of the mass. The xylene was removed by subsequent distillation in a vacuum at an elevated temperature to a residual content of less than 500 parts per million.

The resulting product PO is a mixture of linear polyurethanes with terminal branching plots (T). A typical ratio of molecular weight of the hydrophilic segment (S) to the molecular weight of the hydrophilic segment (P) in the polyurethanes PU is 1:1.7 (if area (S) consist of 20 ethylenoxide residues).

The molar ratio plots (B) to sections (D) is 1:1,75.

Read the t PU was dispersible in 826,6 g of water, and the resulting dispersion was cooled to room temperature (25°C). The mixture of polymers PU (Mn4000 g/mol, Mw9000 g/mol) was in the form of an aqueous dispersion with a solids content of 20.0% of the mass. The viscosity of the aqueous dispersion of politicalisation PU a 10% concentration. at 23°C was 150 MPa·s (shear rate 100 1/s, respectively 350 1/s, which is expressed strukturnovyazkikh behavior.

The determination of the critical concentration of micelle formation

The critical micellization concentration used according to the invention the polyurethanes in water was determined by dynamic light scattering.

To determine the CMC used a goniometer SP-86 (manufacturer firm ALV-Laser Vertriebsgesellschaft MWN, Langen, Germany) in the form of a combined DLS/SLS-device. The device also included a correlation block ALV 5000 and xenon/neon laser with a wavelength of 633 nm (both nodes were also made by firm ALV, Langen). The measurements were carried out at concentrations of from 0.0001 to 10 g/l, an angle measuring 90° and 23°C. the measurement Results were evaluated using known from the prior art program CONTIN (forced inversion) intensive distribution (the program also developed by ALV, Langen).

Comparative example

For comparison, the determined critical concentration michellebruno is of non-ionic, hydrophobically modified ethoxylated polyurethane according to the prior art, derived from stearyl alcohol, diisocyanate and polyethylene glycol (product Aculyn 46 company Rohm & Haas). Product Aculyn®46 did not have a measurable critical concentration of micelle formation. In the concentration range from 0.001 to 10 g/l as a main component in the region of wavelengths from 100 to 500 nm is constantly watched by large indefinite units.

KCM polyurethanes according to the present invention

For mixtures of polyurethanes PU, respectively PU, the above examples of the synthesis of 1 and 2 at a concentration of 0.1 g/l were found well-defined micelles having an average diameter of 30 nm. Thus, the critical concentration of micelloformation for both of these samples were less than 0.1 g/l For polyurethanes PU obtained according to the above synthesis example 4, at a concentration of 1 g/l were found micelles with a diameter of 17 nm, and micelles with an average size of 15 nm and a small indefinite quantity of units size of about 200 nm. Thus, the critical concentration of micelloformation in this case also corresponds to the region of concentrations below 0.1 g/l

Example formulations 1. Preparation of cosmetic preparations Z.1.1-Z.1.5 on non-ionic basis using polyurea the s PU-PU

Cosmetic preparations were prepared by adding the water phase to the oil phase and the subsequent mixing of the resulting emulsion of the type oil-in-water with preservative (phase C). Received cosmetic preparations Z.1.1-Z.1.5 on non-ionic basis (see table 1).

Table 1
The composition of cosmetic products Z.1.1-Z.1.5 on non-ionic basis
PhaseIngredientsZ.1.1Z.1.2Z.1.3Z.1.4Z.1.5
Phase AndCetearate-6, stearic alcohol2.0 g2.0 g2.0 g2.0 g2.0 g
Cetearate-252.0 g2.0 g2.0 g2.0 g2.0 g
Cetearyl alcohol2.5 g2.5 g2.5 g 2.5 g2.5 g
Paraffin oil5.0 g5.0 g5.0 g5.0 g5.0 g
Cetearyl ethylhexanoate5.0 g5.0 g5.0 g5.0 g5.0 g
PhasePolyurethanePO 0.5 gPO 0.5 gPU 2.0 gPU 2.0 gPO 0.5 g
1,2-Propylene glycol5.0 g5.0 g5.0 g5.0 g5.0 g
Water77,5 g77,5 g76,0 g76,0 g77,5 g
PhaseThe preservative Euxyl®K from the company Schulke&Mayr (fenoc-cetanol, methylparaben,ethylparaben, butylparaben, propylparaben, isobutyl-Raben)0.5 g0.5 g0.5 g0.5 g0.5 g

Example 2. Preparation of cosmetic preparations Z.2.1-Z.2.5 on non-ionic basis using polyurethanes PU-PU

Cosmetic preparations were prepared by adding the water phase to the oil phase and the subsequent mixing of the resulting emulsion of the type oil-in-water with preservative (phase C). Received cosmetic preparations Z.2.1-Z.2.5 on non-ionic basis (see table 2).

2.0 g
Table 2
The composition of cosmetic products Z.2.1-Z.2.5 on non-ionic basis
PhaseIngredientsZ.2.1Z.2.2Z.2.3Z.2.4Z.2.5
Phase AndGlyceryl stearate2.0 g2.0 g2.0 g2.0 g2.0 g
Stearyl alcohol2.0 g2.0 g2.0 g2.0 g
Cyclopentasiloxane, cyclo-hexanelactam3.0 g3.0 g3.0 g3.0 g3.0 g
Dicaprylyl ether3.0 g3.0 g3.0 g3.0 g3.0 g
Dimethicone2.0 g2.0 g2.0 g2.0 g2.0 g
Aluminum starch octenyl-succinate1.0 g1.0 g1.0 g1.0 g1.0 g
PEG-40 stearate2.0 g2.0 g2.0 g2.0 g2.0 g
F is for PolyurethanePO 0.5 gPO 0.5 gPU 2.0 gPU 2.0 gPO 0.5 g
Glycerin5.0 g5.0 g5.0 g5.0 g5.0 g
Water79,0 g79,0 g77,5 g77,5 g79,0 g
PhaseThe preservative Euxyl®K from the company Schulke&Mayr (fenoc-cetanol, methylparaben, ethylparaben, butylparaben, propylparaben,isobutyl-Raben)0.5 g0.5 g0.5 g0.5 g0.5 g

Determination of dynamic viscosity of drugs from excipients

Dynamic viscosity of aqueous preparations, which were attended by additional excipients, for example, the dynamic viscosity of cosmetic products prepared in accordance with the following when the EPAM, was determined by using a Brookfield viscometer type DV-ll+Pro (model RVDVII+Pro, firm Brookfield). As the measuring system used RV-spindle (20°C, speed 20 rpm).

The viscosity of cosmetic products Z.1.1-Z.1.5 on non-ionic basis depending on the salt concentration

Table 3
The viscosity of cosmetic products Z.1.1-Z.1.5 depending on the salt concentration
MedicationAdd salt successive portions Dynamic viscosity [PA·s]
0% of the mass. NaCl0.5% mass. NaCl2,0% of the mass. NaCl5,0% of the mass. NaCl10,0% of the mass. NaCl
Z.1.133,224,013,27,97,0
Z.1.239,529,814,811,011,3
Z.1.34,16,1 6,37,78,6
Z.1.43,04,3a 3.94,32,4
Z.1.511,3the 9.76,95,1the 3.8
Introduction to phase In the total amount of salt Dynamic viscosity [PA·s]
Z.1.133,6-39,339,6-

Adding salt to the drug Z.1.3 observed increase in viscosity, while adding salt to the drug Z.1.4 viscosity remains essentially unchanged. A sufficiently high effect of thickening drugs Z.1.1, Z.1.2 and Z.1.5 also reach portions when adding salt.

The viscosity of cosmetic products Z.2.1-Z.2.5 on non-ionic basis depending on the salt concentration

Table 4.
The viscosity of cosmetic products Z.2.1-Z.2.5 depending on the concentration to the supplied serial portions of salt
MedicationDynamic viscosity [PA·s]
0% of the mass.0.5% mass.2,0% of the mass.5,0% of the mass.10,0%
NaClNaClNaClNaClmass. NaCl
Z.2.123,318,015,010,65,3
Z.2.216,411,29,57,64,6
Z.2.313,114.4Vthe 15.618,020,3
Z.2.4of 5.413,013,315,213,7
Z.2.527,030,623,5 23,816,1

When adding salt to the drug Z.2.5 observed stability of the viscosity, which in some cases even increases. This effect is even more characteristic of drugs Z.2.3 and Z.2.4, as evidenced by a strong increase in the dynamic viscosity by adding 10% of the mass. the salt. High thickening effect when the rationed supply of salt reach for drugs Z.2.1 and Z.2.2.

The following are typical offered in the invention of the drugs, but the present invention is not limited to these examples.

In the absence of other indications of the quantitative data are given in mass percent (% wt.).

/tr>
Sunscreen 1
Name according to the item
%IngredientINCl
And58,7Water demineralizedAqua
0,1Edeta®BD Disodium EDTA
1,0ButyleneglycolButyleneglycol
2,0Uvinul®MS 40Benzophenone-4
1,0TriethanolamineTriethanolamine
0,5Panthenol®75 WPanthenol
2,4Polyurethane PU
In5,0Neo Heliopan®OSOctyl salicylate
3,0Eusolex®9020Avobenzone
5,0Neo heliopan®HMSHomosalate
8,0Uvinul®N 539 TOctocrylene
the 1,0Cremophor®GS 32Polyglyceryl-3 distearate
1,0Cremophor®A 6Cetearate-6, stearyl alcohol
1,0Cremophor®A 25Cetearate-25
2,0Lanette®ESodium Cetearyl sulfate
0,5Span®60Sorbitan stearate
3,0Luvitol®LiteHydrogenated polyisobutylene
2,0Lanette®AboutCetearyl alcohol
1,5Lanette®16Cetyl alcohol
1,0Cetiol®SB 45Butyrospermum parkii (Shea butter)
0,1Vitamin E acetateTocopheryl acetate
0,2Bisabolol (racemic)Bisabolol
0,5Glydant®LTDDMDMH as the

Cooking

Phases a and b separately heated to a temperature of about 80°C.

The phase b is introduced into phase a and homogenize by briefly stirring.

The mixture of phases a and b with stirring, cooled to a temperature of about 40°C, add phase C to phase a with stirring, cooled to room temperature and again homogenized by brief stirring.

Viscosity

a) 7,2 PA·s without polyurethane PU (Brookfield viscometer RVD VII+spindle No. 6),

b) 56,2 PA·s with polyurethane PU (Brookfield viscometer RVD VII+spindle No. 7).

In addition to the specified sunscreen containing polyurethane PU, there are also sunscreens containing one or more polyurethanes from PU to PU.

Sunscreen 2
%IngredientName according to the item
INCl
And2,0Cremophor®6Cetearate-6, stearyl alcohol
2,0Cremophor®25Cetearate-25
5,0Luvitol®NETWORKCetearyl ethylhexanoate
5,0Paraffin oil,Mineral oil
plastic
2,5Lanette®AboutCetearyl alcohol
In5,0Z-cote®MAXZinc oxide, dimethoxybiphenyl-
LAN/ triethoxycaprylylsilane sshi-
th polymer
2,4Polyurethane PU
5,01,2-Propylene glycolPropylene glycol
70,5Water demineralize-Water
EN
D0,5Euxyl®300Phenoxyethanol, methylparaben,
ethylparaben, butylparaben, Pro-
palparan

Cooking

Phase And heated to 80°C and injected into her phase C.

Phase a+b homogenized for three mi the ut.

The phase heated to 80°C., introducing into the mixture a+b and homogenize.

The emulsion with stirring, cooled to 40°C.

Add phase D to phase a with stirring, cooled to room temperature and homogenized.

Viscosity

a) to 1.5 PA·s without polyurethane PU (Brookfield viscometer RVD VII+spindle No. 6),

b) 56,2 PA·polyurethane PU (Brookfield viscometer RVD VII+spindle No. 6).

In addition to the specified sunscreen containing polyurethane PU, there are also sunscreens containing one or more polyurethanes from PU to PU.

Day cream for UV protection
%IngredientName according to the item
INCl
And
3,00Tego Saga®450Polyglyceryl-3-methylglucose
distearate
3,00Lanette®18 Stearyl alcohol
2,00Cutina®GMSLiterallayout
4,00Estol®1540Ethylhexylamine
5,00Luvito®L EHOCetearyl ethylhexanoate

%IngredientName according to the item
INCl
8,00Uvinul®APlusEthylhexylacrylate,
Diethylaminoethanol-
Dhexylbenzoate
D
5,00
D-panthenol 50 PPanthenol, propylene glycol
0,10Edeta BDDisodium EDTA
1,0-5,0Polyurethane PU
100Water demineralizedWater demineralized
j
0,20
Bisabolol naturalBisabolol
q.s.**Perfume oil
0,50Concentrated gel aloe 10/1Water, juice of leaves of Aloe Barbadensis
0,50Euxyl®300Phenoxyethanol, methylparaben, butylparaben, ethylparaben, propylparaben, isobutylene-Ben
a) a Sufficient number

Cooking

Phases a and b separately heated to a temperature of about 80°C.

The phase b is introduced into phase a and homogenize by briefly what remesiana.

The mixture of phases a and b with stirring, cooled to a temperature of about 40°C, add phase C to phase a with stirring, cooled to room temperature and re-homogenized by brief stirring.

In addition to the specified day cream containing polyurethane PU, there are also a day cream that contains one or more polyurethanes from PU to PU.

Preparation for makeup
%IngredientName according to the item
INCl
And
4,00Dracorin®100 SELiterallayout, PEG-100 stearate
1,00Uvinul®A PlusDiethylaminobenzoic-
sevenseat
3,00Uvinul®MC 80Ethylhexylacrylate
0,50Emulmetik®100Lecithin
0,50
R
Rylo®PG 11Polyglyceryl dimer soyat
D
0,35
Sicovit®brown 75 E 172The iron oxides
2,00Sicovit®red 30 E 172The iron oxides
1,00Sicovit®yellow 10 E 172The iron oxides
2,25Prisorine®3630Trimethylolpropane triisostearate
5,50Dow corning®345 FluidCyclopentasiloxane, cyclohexa-siloxane
4,00Tegosoft®OPEthylhexylamine
1,50Jojoba oilOil from the seeds of Simmondsia chinensis (jojoba)

%IngredientName according to the item
INCl
2,00Miglyol®840Propylene glycol dicaprylate/di
kapat
1,50Almond oil slideOil sweet almond (prunus
someamygdalus dulcis)
0,50Vitamin E acetateTocopherylacetate
1,00Cetiol®SB 45Butyrospermum parkii (Shea butter)
5,00Uvinul®TUTitanium dioxide, trimethoxysilyl-
Lillian
0,50Dehymuls®PGPHPolyglyceryl-2 typologically-
stearate
D
5,001,2-Propylene glycolPropylene glycol
(beauty)
0,50Lutrol®F 68Poloxamer 188
0,10Edeta BDDisodium EDTA
1,0-5,0Polyurethane PU
100 EWater demineralizedWater demineralized
1,00Euxyl®300Phenonip, Phenoxyethanol, methyl paraben, ethylparaben, balipara-Ben, propylparaben, isobutyl-Raben
0,20Bisabolol, racemicBisabolol
q.s.**Perfume oil
*)Enough

Cooking

Phase a, b, C and D are heated separately from each other up to 70°C.

Phase In homogenized through a three-roll mill, is introduced into phase a and mix.

Components subjected to repeated short-term homogeneization.

Phase With dissolved in a mixture of phases a+b and mix.

Phase D was dissolved in a mixture of phases a+b+C, stirred and homogenized.

Phase with stirring, cooled to approximately 40°C, add phase E, the mixture is cooled to room temperature and briefly homogenize.

In addition to the specified product for makeup containing polyurethane PU, there are also preparaty makeup that contains one or more polyurethanes from PU to PU.

td align="left"> D-panthenol 50 P Bisabolol
Tinted day cream
%IngredientName according to the item
INCl
And
100Water demineralizedWater demineralized
5,00Glycerol 87%Glycerin
4,00Panthenol, propylene glycol
0,75Cloisonne®GoldMica, titanium dioxide, oxides
iron
0,25Cloisonne®Super RougeMica, iron oxides
1,0-5,0Polyurethane PU
B
3,00Uvinul®APIusDiethylaminobenzoic-
sevenseat
7,00Luvitol®LiteHydrogenated polyisobutylene
1,50Lanette®AboutCetearyl alcohol
1,50Cutina®GMSLiterallayout
3,50Cetiol®SB 45 Butyrospermum parkii (Shea butter)
3,50Olive oilOlive oil (l aigeria)
1,00Eumulgin®2Cetearate-20
1,00Cremophor®A6Cetearate-6, stearyl alcohol
1,00Cetiol®OEDicaprylyl ether
0,05ButylacetylButylacetyl
C
0,20Sodium ascorbyl phosphateSodium ascorbyl phosphate
5,00Water demineralizedWater demineralized
D
1,00Euxyl®RE 9010Phenoxyethanol, these l Hexi l glycerol
0,25Bisabolol, racemic
1,00Vitamin E acetateTocopherylacetate

%IngredientName according to the item
INCl
q.s.*)Perfume oil
*)Enough

Cooking

Phase And heated to 80°C.

The phase b is heated to about 80°C, under stirring introduced into phase a and homogenize.

Phase a+b with stirring, cooled to approximately 40°C, add phase C+D, with stirring, cooled to room temperature and briefly homogenize.

In addition to the specified tinted day cream containing polyurethane PU, there are also tinted day cream that contains one or more polyurethanes from PU to PU.

Deodorizing lotion
%IngredientThe name of the agreement is but the item
INCl
And
1,50Cremophor®6Cetearate-6, stearyl alcohol
1,50Cremophor®25Cetearate-25
2,00Cremophor®WITH 40PEG-40 gidrirovannoe castor oil
2,00Cutina®MSLiterallayout
2,00Lanette®aboutCetyl alcohol
2,00Softisan®100Hydrogenated cocoglyceride
8,00Cetiol®VDecillia
0,50Abil®In 8843PEG-14 Dimethicone
0,30FarnesolFarnesol
B
Q.s.*)PreservativePreservative
1,0-5,0Polyurethane PU
100Water demineralizedWater demineralized
C
q.s.*} nPerfume oilFragrant substance
D
5-20Locron®LAluminum hydrochloride
*)Enough

Cooking

Phases a and b are heated separately from one another to about 80°C.

The phase b under stirring introduced into phase a and briefly homogenize.

Phase a+b is cooled to approximately 40°C. the homogenization add phases C and D and with stirring, cooled to room temperature.

In addition to the specified deodorizing lotion containing polyurethane PU, made deodorant is olony, containing one or more polyurethanes from PU to PU.

Hair wax containing pigments
%PhaseIngredientName according to nomenclature INCl
5AndCremophor®CO 40 PEG-40Gidrirovannoe castor oil
15Cremophor®A 25Cetearate-25
0,5-10Polyurethane PU
15Luvitol®LiteHydrogenated polyisobutylene
3Marlipal®MGLaureth-7
2Brij®98IG-20
1Euxyl®PE 9010 Phenoxyethanol and Ethylhexylglycerin Rin
5InAbil®B 88183PEG/BCP-20/6 Dimethicone
100Water demineralizedWater demineralized
1Gemtone®EmeraldMica, titanium dioxide, chrome oxide (green) and Prussian blue

Cooking

I: separately weighted phase a and heat up to 80°C under stirring,

II: phases a and b are connected to each other at 80°C and stirred,

III: the mixture of phases a+b with stirring, cooled to room temperature.

In addition to the wax for hair containing polyurethane PU and pigments are also produced of wax for hair contains pigments and one or or more of polyurethanes from PU to PU.

Hair gel with UV protection
Phase%Name according to nomenclature INClIngredient
And 44,55Water demineralized
0,45Cross-linked polymer of an acrylate/acrylate C10-30 alkyl
In0,36Aminomethyl propanol
0,66PanthenolD-panthenol 75W®
10,00Copolymer of polyvinylpyrrolidone/VI-ylaceticLuviskol®VA 64 W
2,50Polyquaternium-46Luviquat®Hold
5,00Sorbitol
0,10Disodium EDTA

Phase%Name according to nomenclature INClIngredient
0,5Benzophenone-4Uvinur MS 40
q.s.*)Perfume
q.s.*)PEG-40 gidrirovannoe castor oilCremophor®WITH 40
q.s.*)Preservative
5,00Alcohol
55Water demineralized
0,5-4Polyurethane PU
*)Enough

Cooking

I: separately weighted phase a, b and C if necessary, homogenized by stirring at room temperature,

II: phase b and a are connected to each other at room temperature and homogenized with stirring, after which the PR is stirring, add phase C and mix thoroughly.

In addition to the hair gel containing polyurethane PU, there are also gels for the hair, containing one or more polyurethanes from PU to PU.

Foam hair
%IngredientName according to the item
INCl
q.s.*)Phase AndDeionizedWater demineralized
water
11,00Luviquat®HoldPolyquaternium 46
1,50Uvinul®MS 40Benzophenone-4 (offset
the triethanolamine 20%
solution)
0,1-3Polyurethane PU
0,40D.l-panthenol 50WPanthenol
0,20Masil®SF 19 CGPEG-8 Medicon
0,40Glydant®Plus liquidDMDMH the as (and) iodopropane-
nilpotent
0,20 PhaseCremophor®CO 40PEG-40 gidrirovannoe castor
oil
0,40Vitamin E acetateTocopheryl acetate
0,20Bell®6101232Fragrant substance
0,70Rhodasurf®L-4Laureth-4
6,00 PhasePropellant A46Propane/isobutane
*)Enough

Cooking

1. The weighting of the components of the phases is As in the above mentioned sequence and stirring until complete dissolution.

2. Weighing components phase and mixing while heating to a temperature of from 40 to 45°C.

3. Combining phases a and b and filling the mixture into the appropriate tanks for the finished foam.

4. Sealing tanks and filling with propellant (phase C).

In addition to this foam for hair containing polyurethane PU, there are also foam for hair that contains one or more polyurethanes from PU to PU.

Facial cream with 3% ascorbylpalmitate sodium
%IngredientName according to the item
INCl
And
2,00Cremophor®6Cetearate-6, stearyl alcohol
2,00Cremophor®25Cetearate-25
3,00Jojoba oilOil from the seeds of Simmondsia
3,00Lanette®AboutCetearyl alcohol
10,00Paraffin oil,Mineral oil
plastic
5,00VaselinePetrolatum
4,00Miglyol®812Caprylic/capric triglyceride
In
5,001,2-propylene glycolPropylene glycol
cosmetic
0,10Edeta BDDisodium EDTA
1,0-5,0Polyurethane PU

td align="left">
%IngredientName according to the item
INCl
0,30Abiol®Imidazolidinyl urea
100Water demineralizedWater demineralized
0,08Sodium hydroxideSodium hydroxide
D
0,50Vitamin E acetateTocopheryl acetate
0,20PhenoxyethanolPhenoxyethanol
3,00Sodium ascorbyl phosphateSodium ascorbyl phosphate

Cooking

Separately heat phase a and b to about 80°C. the Introduction phase Into phase a and homogenize by stirring. The introduction of phase With the phase a+b and homogenization by stirring. Cooling to about 40°C when PE is emisiuni.

Introduction phase and short-term additional homogenization by stirring.

Cooling to room temperature under stirring.

In addition to the specified face cream containing polyurethane PU, there are also creams for the face, containing one or more polyurethanes from PU to PU.

The reduction in the average size of the droplets of the emulsion of the type oil-in-water
%IngredientName according to the item
INCl
Phase And
2,0Lanette®AboutCetearyl alcohol
5,0Finsolv®TNC12-15 alkylbenzoic
10,0Miglyol®812Caprylic/capric trigly-
zerit
5,0Cetiol®In/td> Dibutyltin
2,0Amphisol®ToPotassium cetilistat
0,5Elfacos®ST-9PEG-45/dodecylphenol copoly-
measures
Phase
5,01,2-Propylene glycol kosmicheskiyPropylene glycol
100Water demineralizedWater
1,0-5,0Polyurethane PU
Phase
0,5Euxyl®300Phenoxyethanol, methylparaben,
ethylparaben, butylparaben, Pro-
palparan

Phase a and heat up approx the RNO to 80°C. The phase b is introduced into phase a and homogenized with stirring. The mixture is cooled under stirring, enter the phase and subjected to short-term homogenization.

In addition to the specified emulsion of the type oil-in-water containing polyurethane PU, there are also emulsions of the type oil-in-water containing one or more polyurethanes from PU to PU.

Cream containing alpha-gidrokshikislotu
%IngredientName according to the item
INCl
And
2,00Cremophor®A6Cetearate-6, stearyl alcohol
2,00Cremophor®A25Cetearate-25
8,00Paraffin oil, viscous-fluidMineral oil
7,00Luvitol®NETWORKCetearyl ethylhexanoate
6,00Cutina®MSLiterallayout
1,00Lanette®16Cetyl alcohol
0,20Abil®350Dimethicone
0,20Bisabolol naturalBisabolol
D
1,00D-panthenol USPPanthenol
3,001,2-Propylene glycol cosmeticPropylene glycol
1,0-5,0Polyurethane PU
5,00Hydroxycitrate
q.s.*)Sodium hydroxideSodium hydroxide
q.s.*)PreservativePreservative

% IngredientName according to the item
INCl
To 100 gWater demineralizedWater demineralized
q.s.*)Perfume oilFragrant substance
*)Enough

Note

Alpha hydroxy acids: lactic acid, citric acid, malic acid, glycolic acid, dihydroxyindole: tartaric acid, betahydroxylase: salicylic acid.

Cooking

Phases a and b separately heated to about 80°C. If necessary, the pH of phase b by NaOH installed in the field 3.

The phase b with stirring, homogenize in phase a and the mixture is subjected to additional short-term homogenization.

Cooling to approximately 40°C, add phase C, re additional homogenization.

In addition to the cream containing polyurethane PU and alpha-hydroxy acids, there are also creams that contain alpha-hydroxy is islote and one or more polyurethanes from PU to PU.

Cream containing vitamin A (acid)
%IngredientName according to the item
INCl
And
1,50Cremophor®25Cetearate-25
1,50Cremophor®6Cetearate-6, stearyl alcohol
3,00Tegin®Glyceryl stearate SE
2,00Lanette®AboutCetearyl alcohol
10,00Luvitol®NETWORKCetearyl ethylhexanoate
5,00Paraffin oil is viscous-fluidMineral oil
0,10D, L-alpha-tocopherolTocopherol
0,10Vitamin a (acid)Tretionin
D
1.0Polyurethane PU
to 5.0
4,001,2-Propylene glycol cosmeticPropylene glycol
0,10Edeta BDDisodium EDTA
Q.s.PreservativePreservative
100Water demineralizedWater demineralized
0,40Triethanolamine cosmeticTriethanolamine
3,00Vitamin E (acetate)Tocopheryl acetate
0,10Vitamin a (acid)One third of the NIN

%IngredientName according to the item
INCl
q.s*)Perfume oilFragrant substance
*) A sufficient amount of

Cooking

Phases a and b are heated separately to about 75°C. the Phase b with stirring, homogenize in phase A. After cooling to about 30°C add phase C.

Note. The drug is prepared without the use of protective gas and Packed in impermeable to oxygen vessels, for example, aluminum cans.

In addition to the cream containing polyurethane PU and vitamin A (acid), there are also creams that contain vitamin A (acid) and one or more polyurethanes from PU to PU.

Cream for hair removal 1
%IngredientName according to nomenclature INCl
And
4,20Lanette®16Cetyl alcohol
1,26Brij® 35Laureth-23
In

%IngredientName according to nomenclature INCl
15,00Luviquat®SagaPolyquaternium-44
0,90D-panthenol USPPanthenol
0,35AllantoinAllantoin
q.s.*)PreservativePreservative
22,40Calcium carbonateCalcium carbonate
10,00Calcium hydroxideCalcium hydroxide
of 5.40Thioglycolate calcium Thioglycolate calcium
100Water demineralizedWater demineralized
From 1.0 to 5.0Polyurethane PU
q.s.*)Perfume oilFragrant substance
*)Enough

Cooking

Phases a and b separately heated to about 80°C.

The phase b with stirring, homogenize in phase a, and then undertake additional short-term homogenization.

Cooling to approximately 40°C, add phase C and re-homogenization.

In addition to the cream for hair removal, the polyurethane-containing PU, there are also creams for hair removal, which contains one or more polyurethanes from PU to PU.

Cream for hair removal 2
%IngredientName according to nomenclature INCl
And
1,00Cremophor®6Cetearate-6, stearyl alcohol
1,00Cremophor®25Cetearate-25
4,00Lanette®AboutCetearyl alcohol
6,00Paraffin oil, viscous flowMineral oil
q.s.*)PreservativePreservative
In
8,00Thioglycolate calciumThioglycolate calcium
2,001,2-Propylene glycol cosmeticPropylene glycol
From 1.0 to 5.0Polyurethane PU
1,00Sodium hydroxideSodium hydroxide
100 Water demineralizedWater demineralized
q.s.*)Perfume oilFragrant substance
*)Enough

Cooking

Phases a and b are heated separately to about 80°C.

The phase b with stirring, homogenize in phase a, and then undertake additional short-term homogenization.

Cooling to approximately 40°C, add phase C and re-homogenization.

In addition to the cream for hair removal, the polyurethane-containing PU, there are also creams for hair removal, which contains one or more polyurethanes from PU to PU.

Conditioning shampoo 1
35.70 barm gsodium Laureth sulfate
6.50 gcocamidopropyl betaine
0.20 gpolyurethane PU
0.50 gpolyquaternium-7, polyquaternium-10, polywater the th-39, poly-
quaterni-44, polyquaternium-67, qualitatsprodukten
chloride and/or polyquaternium-87
0.10 gpreservative
0.10 gperfume oil/essential oil
To 100 gdemineralized water

In addition to the specified conditioning shampoo 1 containing polyurethane PU, manufacture & conditioning shampoos containing one or more polyurethanes from PU to PU.

Conditioning shampoo 2
35.70 barm gsodium Laureth sulfate
6.50 gcocamidopropyl betaine
0.50 gpolyurethane PU
0.20 gqualitatsprodukten chloride
0.10 gpreservative
0.10 gperfume oil / essential oil
To 100 gdemineralized water

In addition to the specified conditioning shampoo 2 containing polyurethane PU, manufacture & conditioning shampoos containing one or more polyurethanes from PU to PU.

Example 3. Conditioning shampoo 3

35.70 barm gsodium Laureth sulfate
6.50 gcocamidopropyl betaine
0.20 gpolyurethane PU

0.50 gpolyquaternium-7, polyquaternium-10, polyquaternium-39, poly-
quaterni-44, polyquaternium-67, qualitatsprodukten
chloride and/or polyquaternium-87
0.10 gpreservative
0.10 gperfume oil / essential oil
To 100 gdemineralized water

In addition to the specified conditioning shampoo 3 containing polyurethane PU, projectors, who are trained & conditioning shampoos, containing one or more polyurethanes from PU to PU.

Example 4. Shampoo

Phase A:
15,00 gcocamidopropyl betaine
10,00 gdisodium cocoamphodiacetate
5,00 gPolysorbate-20
5,00 gdisillusioned
0.50 gpolyquaternium-7, polyquaternium-10, polyquaternium-39, poly-
quaterni-44, polyquaternium-67, qualitatsprodukten
chloride and/or polyquaternium-87
0.20 gpolyurethane PU
0.10 gperfume oil / essential oil
q.s.*)preservative
2,00 gLaureth-3

100water demineralized
q.s.*)citric acid
Phase:
3.00 gPEG-150 distearate
*)Enough

Cooking

Weighed and dissolved components of phase a, the pH ustanavlivaut in the interval from 6 to 7. Add phase B, and phase is heated to 50°C. Cooling to room temperature under stirring.

In addition to the shampoo containing polyurethane PU, there are also shampoos that contains one or more polyurethanes from PU to PU.

Shampoo
30,00 gsodium Laureth sulfate
6,00 gsodium cocoamphoacetate
0.50 gpolyquaternium-7, polyquaternium-10, polyquaternium-39, poly-
quaterni-44, polyquaternium-67, qualitatsprodukten
chloride and/or polyquaternium-87
0.50 gpolyurethane PU
3.00 gsodium Laureth sulfate, glycol distearate, cocamide monatana Lamin, Laureth-10

2,00 gDimethicone
q.s.*)perfume
q.s.*)preservative
q.s.*)citric acid
1,00 gsodium chloride
100water demineralized
*)Enough

In addition to the shampoo containing polyurethane PU, there are also shampoos that contains one or more polyurethanes from PU to PU.

Shower gel 1
20,00 gammonium Laureth sulfate
15,00 gammonium lauryl
0.50 gpolyurethane PU
0.50 g
quaterni-67, qualitatsprodukten chloride and/or poly-
quaterni-87
2.50 gsodium Laureth sulfate, glycol distearate, cocamide monoamino-
Lamin, Laureth-10
0.10 gperfume oil / essential oil
q.s.*)preservative
0.50 gsodium chloride
100water demineralized

*)Enough

In addition to the shower gel 1 containing polyurethane PU, there are also shower gels, containing one or more polyurethanes from PU to PU.

Shower gel 2

5,00 g
40,00 gsodium Laureth sulfate
5,00 gdisillusioned
polyurethane PU
1,00 gpanthenol
0.50 gpolyquaternium-10, polyquaternium-44, polyquaternium-67, qualitatsprodukten chloride and/or polyquaternium-87
0.10 gperfume oil / essential oil
q.s.*)preservative
q.s.*)citric acid
2,00 gsodium chloride
100water demineralized
*)Enough

In addition to the shower gel 2 containing polyurethane PU, there are also shower gels, containing one or more polyurethanes from PU to PU.

Shampoo
12.00 gsodium Laureth sulfate
1.50 gdisillusioned
0.50 gpolyquaternium-10, floor and quatern and St-44, polique ERNI-67, qualitatsprodukten chloride and/or polyquaternium-87
0.50 gpolyurethane PU
5,00 gcocoglucoside glyceriae
2,00 gsodium Laureth sulfate, glycol distearate, cocoamide monoethanolamine, Laureth-10
q.s.*) preservative
q.s.*) Sunsetyelow C.I. 15985
0.10 gperfume oil / essential oil
1,00 gsodium chloride
100water demineralized
*)Enough

In addition to the shampoo containing polyurethane PU, there are also shampoos that contains one or more polyurethanes from PU to PU.

The above polyurethanes can also be used in products for hair styling, especially in the pins for the hair (aerosol foams with propellant and pulverizing without propellant foams, sprays for hair (pulverizing without propellant) and gels for hair. The propellants are commonly used working environment. P is impactfully the propellants are mixtures of propane/butane, as well as pentane, dimethyl ether, 1,1-differetn (HFC-152), carbon dioxide, nitrogen, or compressed air.

Aerosol foam hair
2,00 gcocodimonium methosulfate
0.10 gperfume oil / essential oil
3.50 gfixing polymer, respectively, the combination comprising,a
for example, polyvinylpyrrolidone, copolymer of viniterra-
lidón with vinyl acetate, polyquaternium-4, polyquaternium-11,
polyquaternium-16, polyquaternium-46, polyquaternium-44, poly-
quaterni-68, a copolymer based on vinylpyrrolidone, metac-
Alameda and of vinylimidazole, and so on
0,80 gpolyurethane PU
q.s.*)preservative
75,00 gwater dem is nerealizovannoe
10,00 gpropane/butane (3.5 bar)
*)Enough

In addition to the specified aerosol foam hair containing polyurethane PU, there are also aerosol foam hair that contains one or more polyurethanes from PU to PU.

Gel for hair styling 1
Phase A:
0.50 gcarbomer or cross-linked polymer, acrylates/C 10-30 alkylacrylate
86,40 gwater demineralized
Phase:
0,70triethanolamine
Phase:
11,00fixing polymer, respectively, the combination comprising,a
for example, polyvinylpyrrolidone, copolymer of viniterra-
lidón with vinyl acetate, polyquaternium-4, polyquaternium-11,
polyquaternium-16, polyquaternium-46, polyquaternium-44, poly-
quaterni-68, a copolymer based on vinylpyrrolidone, metac-
Alameda and of vinylimidazole, and so on
0.20 gPEG-25 RAV
2,00 gpolyurethane PU
0.10 gperfume oil / essential oil
q.s.*)PEG-14 Dimethicone
q.s.*)preservative
0.10 gTocopheryl acetate
*)Enough

In addition to the gel for hair styling 1 containing polyurethane PU, there are also gels hair styling, containing one or more polyurethanes from PU to PU.

Gel for hair styling 2
Phase A:
0.50 gcarbomer or cross-linked polymer and relate/S 10-30 alkylacrylate
91,20 gwater demineralized
Phase:
0,90 gtetrahydroxyphenylchlorin
Phase:
7,00 gcopolymer of vinylpyrrolidone with vinyl acetate
0,70polyurethane PU
0.20 gperfume oil / essential oil
q.s.*)preservative
0.10 gpropylene glycol
*) A sufficient amount of

In addition to the gel for hair styling 2 containing polyurethane PU, there are also gels hair styling, containing one or more polyurethanes from PU to PU.

2,00 g
Wax cream, hair styling
6,00 gCaprylic/capric triglyceride
3.00 gliterallayout
cetyl alcohol
3.50 gpolyurethane PU
0.50 gcremophor A6

0,70cremophor A25
0.50 gDimethicone
0.50 gvitamin E acetate
2,00 gCaprylic/capric triglyceride and sodium acrylate copolymer
1,00 gD-panthenol USP
0.10 gethylenediaminetetraacetic acid
10,00 gfixing polymer
q.s.*)preservative
To 100 gwater demineralized
*)Enough

In addition to the specified wax cream, hair styling, containing polyurethane PU, there are also wax creams for hair styling, containing one or more polyurethanes from PU to PU.

Paste hair styling
3.00 gKollicoat IR (BASF)
q.s.*)preservative
2,00 gfixing polymer
4,00 gthe copolymer acrylates/beenet-25 methacrylate
0,70polyurethane PU
0.50 gDimethicone copolyol
0.10 gethylenediaminetetraacetic acid
0.20 gbenzophenone-4

To 100 g of demineralized water
*)Enough

In addition to this slurry hair styling containing polyurethane PU, are also produced pulp for hair styling, containing one or more polyurethanes from PU to PU.

Sprayable gel
Phase A:
1,25 gfixing polymer
96,15 gwater demineralized
Phase:
0,70the copolymers of acrylate/steareth-20 itaconate
0.10 gpropylene glycol
0.50 gpolyurethane PU
0.10 gglycerin
0.10 gperfume oil / essential oil
q.s.*)preservative
Phase:
0,70triethanolamine
*)Enough

In addition to the specified sprayable gel containing polyurethane PU, there are also sprayable gels containing one or more polyurethanes from PU to PU.

Drugs that are suitable according to the invention for use as sprays for hair styling, can oblad is th for example, the following composition.

Pulverizeroaiu hair spray
11,20 gPEG/BCP-25/25 Dimethicone/acrylate copolymer or acrylate copolymer
2,80 gcopolymer of vinylpyrrolidone with vinyl acetate
of 1.34 gaminomethylpropanol
0,30 gpolyurethane PU
0.10 gperfume oil / essential oil
of 11.26 gwater demineralized
73,00 galcohol

In addition to the specified pulverizing hair spray containing polyurethane PU, there are also pulverizeroaiu sprays for hair that contains one or more polyurethanes from PU to PU.

Pulverizeroaiu hair spray VOC55
2,00 gcopolymer based on vinylpyrrolidone, methacrylamide and
VI is elimidate
1,90 gpolyquaternium-46
2,00 gpolyurethane PU

0.10 gperfume oil / essential oil
55,00 galcohol
39,00water demineralized

Decorative cosmetic compositions.

In addition to the specified pulverizing hair spray VOC55 containing polyurethane PU, there are also sprays for hair that contains one or more polyurethanes from PU to PU.

Liquid makeup
Phase A:
1.70 gliterallayout
1.70 gcetyl alcohol
1.70 gcetearate-6
1.70 gcetearate-25
5.20 gCaprylic/capric triglyceride
5.20 g mineral oil or Luvitol®Lite (hydrogenated priisalu tilen according to the nomenclature INCl)
Phase:
q.s.*)preservative
4,30propylene glycol
2.50 gpolyurethane PU

59,50 gwater demineralized
Phase:
0.10 gperfume oil / essential oil
Phase D:
2,00 gthe iron oxides
12.00 gtitanium dioxide
*)Enough

In addition to the specified liquid makeup containing polyurethane PU, made preparations liquid makeup that contains one or more polyurethanes from PU to PU.

Contour eye pencil
Phase A:
40,60 gdistilled water
0.20 gdisodium EDTA
q.s.*)preservative
Phase:
0,60 gxanthan gum
0.40 gWigan
3.00 gbutyleneglycol
0.20 gPolysorbate-20
Phase:

15,00 gthe iron oxide / aluminum powder / silicon dioxide (for example, Sicopearl®Fantastico Gold Basf or other eye-catching pigments)
Phase D:
10,00 gwater demineralized
25,00 gfixing polymer, respectively combinations containing, for example, polyvinylpyrrolidone, copolymer of viniterra-lidón with vinyl acetate, policv the thorns-4, polyquaternium-11, polyquaternium-16, polyquaternium-46, polyquaternium-44, poly-quaterni-68, polyurethane-1 or a copolymer based on vinyl-pyrrolidone, methacrylamide, vinylimidazole or other polymers
5,00 gpolyurethane PU
*)Enough

In addition to the specified contour of the pencil containing polyurethane POOL, there are also contour pencils, containing one or more polyurethanes from PU to PU.

Free water
Phase A:
3.00 gpolyurethane PU
0.10 gperfume oil / essential oil
0,30 gbisabolol
Phase:

3.00 gglycerin
1,00 gthe hydroxyethyl of atildigini phosphate
5,00 gextract of Hanamel the sa, the distillate
0.50 gpanthenol
q.s.*)preservative
87,60 gwater demineralized
*)Enough

In addition to this free water containing polyurethane PU, there are also drugs in the form of free water, containing one or more polyurethanes from PU to PU.

Cleansing paste for the face with a peeling effect
Phase A:
73,00 gwater demineralized
1.50 gpolyurethane PU
q.s.*)preservative
Phase:
q.s.*)perfume oil
7,00 gpotassium Cocoyl hydrolyzed protein
4,00 gconditioning polymer, respectively combinations containing private the deposits-7, polyquaternium-10, polyquaternium-39, polyquaternium-44, polyquaternium-67, qualitatsprodukten chloride or polyquaternium-87

Phase:
1.50 gtriethanolamine
Phase D:
13,00polyethylene (Luwax And™ BASF)
*)Enough

In addition to those listed cleansing pastes containing polyurethane PU, there are also drugs in the form of a cleansing paste for the face, containing one or more polyurethanes from PU to PU.

Soap
Phase A:
25,00 gpotassium Cocoate
20,00 gdisodium campolieta
2,00 glauramid diethanolamin
1.0 gglycol stearate
2,00 g
0.50 gconditioning polymer, respectively combinations containing polyquaternium-7, polyquaternium-10, polyquaternium-39, polyquaternium-44, polyquaternium-67, qualitatsprufer-trimani chloride or polyquaternium-87
50,00 gwater demineralized
q.s.*)citric acid
Phase:
q.s.*)preservative

0.10 g perfume oil / essential oil
*)Enough

In addition to the specified soap containing polyurethane PU, there are also preparations soap, containing one or more polyurethanes from PU to PU.

Cleansing milk for face-type oil-in-water
Phase A:
1.50 gcetearate-6
1.50 gcite the pet-25
2,00 gliterallayout
2,00 gcetyl alcohol
10,00 gmineral oil
Phase:
5,00 gthe propylene glycol
q.s.*)preservative
1,00 gconditioning polymer, respectively combinations containing polyquaternium-7, polyquaternium-10, polyquaternium-39, polyquaternium-44, polyquaternium-67, qualitatsprodukten chloride or polyquaternium-87
to 66.30 gwater demineralized
Phase:
0.20 gpolyurethane PU
10,00 gCetearyl octanoate

Phase D:
0.40 gtetrahydroxypropyl Ethylenediamine
Phase E:the
0.10 gperfume oil / essential oil
0.10 gbisabolol
*)Enough

In addition to the specified cleansing milk containing polyurethane PU, there are also drugs in the form of a cleansing milk that contains one or more polyurethanes from PU to PU.

Transparent soap
4,20 gsodium hydroxide
of 3.60 gdistilled water
5,00 gconditioning polymer, respectively combinations containing polyquaternium-7, polyquaternium-10, polyquaternium-39, polyquaternium-44, polyquaternium-67, qualitatsprodukten chloride or polyquaternium-87
5,00 gpolyurethane PU
22,60 gpropylene glycol
18,70 gglycerin
5.20 gcocoamide diethanolamine
2,40 gkokumin oxide
4,20 gsodium lauryl
7.30 gmyristic acid

16,60 gstearic acid
5.20 gtocopherol

In addition to the specified transparent soap containing polyurethane PU, there are also drugs in the form of transparent soap that contains one or more polyurethanes from PU to PU.

Shaving foam
6,00 gcetearate-25
5,00 gpoloxamer 407
52,00 gwater demineralized
1,00 gtriethanolamine
5,00 gpropylene glycol
1,00 gPEG-75 lanolin oil
2,00 gthe conditioning polymer according to the combination of sod is readie polyquaternium-7, polyquaternium-10, polyquaternium-39, polyquaternium-44, polyquaternium-67, qualitatsprodukten chloride or polyquaternium-87
3.00 gpolyurethane PU
q.s.*)preservative
0.10 gperfume oil / essential oil
25,00 gsodium Laureth sulfate
*)Enough

Packing: 90 parts of active substance and 10 parts of a mixture of propane to butane ratio of 25:75.

In addition to this shaving foam, the polyurethane-containing PU, there are also preparations shaving foam containing one or more polyurethanes from PU to PU.

After shave balm
Phase A:
0.25 gpolyurethane PU
1.50 gTocopheryl acetate
0.20 gbisabolol
10,00 gCaprylic/capric trigly is Eric
q.s.*)perfume
1,00 gconditioning polymer, respectively combinations containing polyquaternium-7, polyquaternium-10, polyquaternium-39, polyquaternium-44, polyquaternium-67, qualitatsprufer-trimani chloride or polyquaternium-87
Phase:
1,00 gpanthenol
15,00 galcohol
5,00 gglycerin
0.05 ghydroxyethylcellulose
1,90 gpolyurethane PU
64,02 gdistilled water

Phase:
0.08 gsodium hydroxide
*)Enough

In addition to the after shave balm containing polyurethane PU, there are also the after shave balms containing one or more of polyure the ANOVA from PU to PU.

Toothpaste
Phase A:
34,79 gwater demineralized
3.00 gpolyurethane PU
20,00 gglycerin
0,76 gmonitoroff sodium
Phase:
1.20 gthe sodium carboxymethyl cellulose
Phase:
0,80 garomatic oil
0.06 gsaccharin
q.s.*)preservative
0.05 gbisabolol
1,00 gpanthenol
0.50 gtocopherylacetate
2,80 gsilicon dioxide
1,00 gthe three-is valium

of 7.90 gacidic calcium phosphate anhydrate
25,29 gacidic calcium phosphate dihydrate
0.45 gtitanium dioxide
*)Enough

In addition to this toothpaste containing polyurethane PU, there are also drugs toothpaste that contains one or more polyurethanes from PU to PU.

Composition for mouthwash
Phase A:
2,00 garomatic oil
4,50 gpolyurethane PU
1,00 gbisabolol
30,00 galcohol
Phase:
0.20 gsaccharin
5,00 gglycerin
q.s.* preservative
5,00 gpoloxamer 407
52,30 gwater demineralized
*)Enough

In addition to the specified structure for mouthwash containing polyurethane PU, there are also compositions for mouthwash that contains one or more polyurethanes from PU to PU.

Adhesive for dentures

Phase A:
0.20 gbisabolol
1,00 gbeta carotene
q.s.*)aromatic oil
20,00 gCetearyl octanoate
5,00 gsilicon dioxide
33,80 gmineral oil
Phase:
5,00 gpolyurethane PU
35,00polyvinyle oligon (20% solution in water)
*)Enough

In addition to the adhesive for dentures containing polyurethane PU, there are also adhesives for dentures, containing one or more polyurethanes from PU to PU.

1. Cosmetic preparation containing a water-dispersible polyurethane (PU) with mostly linear main chain composed of alternating hydrophilic and hydrophobic areas, and:
a. both end plot (T) is hydrophobic and at least one of the two hydrophobic end sections (T) polyurethane is a branched alkyl residue,
b. directly to each plot (T) attached hydrophilic segment (S),
c. at least one end of each of the sections (S) directly attached to at least one hydrophobic region (D), and
d. and the main chain contains at least one hydrophilic segment (P), and if more than one plot (B) two sites (R) separated by at least one hydrophobic segment (D),
and the polyurethane includes at least three hydrophilic area, the ratio of the molecular weight of any of the hydrophilic areas (S) to the molecular weight of any of the hydrophilic areas (P) is in the range from 1:1.4 to 1:140, at least two hydrophobic segment (D)are aliphatic diisocyanate residues and at least one hydrophilic segment (R) is the remnant of a polyether with srednetsenovoj molecular weight of at least 1500 g/mol.

2. A cosmetic product according to claim 1, where the polyurethane is a mixture of polyurethanes PU, terminal hydrophobic sections (T) which are branched alkyl areas.

3. A cosmetic product according to claim 1, all the hydrophilic parts of the polyurethane are remnants of the polyether.

4. A cosmetic product according to claim 1, with at least two hydrophilic segment (S) of polyurethane are ethylenoxide remains.

5. A cosmetic product according to claim 1, and Brednikova molecular weight of at least one hydrophilic segment (R) polyurethane ranges from 1500 to 10000 g/mol.

6. A cosmetic product according to claim 1, which contains at least 0.5 wt.% at least one salt and at least 0.1 wt.% at least one surface-active substance.

7. A cosmetic product according to claim 1, which is an emulsion of the type oil-in-water".

8. A cosmetic product according to claim 1, which is a light shielding drug and contains zinc oxide and/or titanium dioxide as a filter to protect from UV rays.

9. A cosmetic product according to one of claims 1 to 8, which further comprises hydrogen peroxide.



 

Same patents:

Anti-wrinkle agents // 2503443

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to chemical-pharmaceutical industry and represents wrinkle-reducing agents containing compounds presented by general formula (1), stereoisomers or pharmacologically acceptable salts thereof, wherein R1 represents a hydrogen atom or a linear or branched alkyl group with 1-8 carbon atoms; R2 represents -SH, -SO3H, -S-X2, -SO-X3, -S02-X4, X2-X4 represents carbon atoms or aliphatic hydrocarbon groups with 1-8 carbon atoms independently, R3 represents a hydrogen atom or an acyl group with a linear or branched alkyl chain with 1-8 carbon atoms, R4 represents a phenyl, tolyl, ethyl phenyl, propyl phenyl, butyl phenyl, pentyl phenyl, hexyl phenyl, methoxyphenyl, ethoxyphenyl, propyl oxyphenyl, butyl oxyphenyl, pentyl oxyphenyl, hexyl oxyphenyl or biphenyl group, m is equal to 0, n is equal to the integer 1 or 2.

EFFECT: invention provides preparing the compounds and cosmetic products possessing the anti-wrinkle effectiveness.

10 cl, 11 ex, 2 tbl, 7 dwg

FIELD: medicine.

SUBSTANCE: invention refers to methods of treating early enamel loss. The presented method of treating or reducing early enamel caries involves the dental application of an effective amount of a dental composition wherein the dental composition has a main formulation containing dicalcium phosphate, wherein the dental composition additionally contains arginine in the free or salt form, and an effective amount of fluoride, wherein arginine is found in the amount of 2 to 10 wt % of total weight of the dental composition.

EFFECT: composition used in the method possess an ability to increase enamel demineralisation that enables treating or reducing early enamel caries.

3 cl, 1 tbl, 4 ex

FIELD: chemistry.

SUBSTANCE: invention relates to field of cosmetology and represents preparation for removing nail polish, which contains organic solvent, cosolvents and target additives characterised by the fact that propylene glycol is used as organic solvent, mixture of ethyl alcohol, ethyl acetate, propylene carbonate, dimethyl glutarate, isopropyl alcohol are used as cosolvents, and mixture of glycerol, gelatin, jojoba oil and denatonium benzoate is used as target additive, with components in preparation being in specified wt % ratio.

EFFECT: invention ensures creation of preparation for removing nail polish without unpleasant smell, with wide spectrum of efficient effect on different types of manicure polishes, as well as characterised by restoring impact on nails, and impossibility of accidental intake as food.

1 ex

FIELD: medicine.

SUBSTANCE: invention refers to cosmetology and represents a cosmetic skin care product in the form of a water-in-oil emulsion, containing: (A) a volatile hydrocarbon oil 3 to 25 wt %, (B) a non-volatile silicon oil 2 to 15 wt %, (C) polyethylene glycol mono- or diisostearate 0.1 to 0.8 wt % containing 4 to 12 groups of oxyethylene, (D) polyoxyethylene and polydimethyl siloxyehtyl dimethicone copolymer 1 to 5 wt %, an d (E) organically modified clay mineral 1.5 to 3 wt %; the ingredients normally introduced into the skin care products - the rest.

EFFECT: provided excellent stability and no oily, slick and creaking sensations.

6 cl, 3 ex, 4 tbl

FIELD: medicine.

SUBSTANCE: invention refers to cosmetology and represents a cosmetic product for lips containing the ingredients (a)-(d): (a) hydrogenised polyisobutene 10 to 30 wt %; (b) one or more methylphenylsicicones 30 to 70 wt % to be separated when mixed with (a) at 25°C specified in trimethyl pentaphenyltrisiloxane, diphenyl siloxyphenyl trimethicone, diphenyl dimethicone and phenyl trimethicone, and containing trimethyl pentaphenyl trisiloxane; (c) one or more lipophilic substrates 0.5 to 8 wt % not separated when mixed both with the ingredient (a), and with the ingredient (b) at 90°C specified in sorbitane sesquiisostearate, propylene glycol monostearate, cetyl-PEG/PPG-10/1 dimethicone and diglycerol diisostearate; and (d) wax 5 to 12 wt %.

EFFECT: provided excellent effect of second adhesion stability immediately after application, long-lasting gloss and stability.

10 cl, 22 ex, 1 dwg, 13 tbl

FIELD: medicine.

SUBSTANCE: invention refers to chemical-pharmaceutical industry and represents a method of delivering a substance from an antiperspirant and/or deodorant composition to an individual's axillary space, involving the application of the anhydrous antiperspirant and/or deodorant composition onto the individual's axillary space, wherein: a) the anhydrous composition contains a base and a metal-organic frame structure formed of reusable porous material (RPM) and a substance adsorbed in the metal-organic frame structure and b) the reusable porous material has a structure degradable in contact with water and releasing a substance with the metal-organic frame structure formed of the porous material (RPM) specified in a groupu consisting of [Co3(biphenyldicarboxylate)34,4'-bipyridine], [Co(biphenyldicarboxylate)(4,4'-bipyridine)], [Zn2(biphenyldicarboxylate)2 (1,2-bipyridineethene)], Mg3(O2C-C10-H6-CO2)3 and combinations thereof.

EFFECT: provided longer release of a flavouring agent after the application of the deodorant/antiperspirant to the individual by the release of the flavouring agent at the moment of perspiration.

16 cl, 2 tbl

FIELD: medicine.

SUBSTANCE: invention refers to cosmetic industry and represents a non-foaming cosmetic composition of an oil-in-water emulsion containing (i) retinol, (ii) at least one polar emollient specified in a group consisting of propylene glycol stearyl ester, propylene glycol isostearate and mixtures thereof (iii) at least one non-polar emollient specified in a group consisting of aromatic or linear esters, Gerbe ester, mineral oils, squalane, isohexadecane, squalene, liquid paraffin and mixtures thereof with the weight ratio of the above polar emollient and the above non-polar emollient is found within the range of approximately 95 to 5 to approximately 40 to 60.

EFFECT: provided considerable reduction of retinoid-caused skin irritation and higher efficacy or retinoid.

11 cl, 3 ex, 7 tbl, 3 dwg

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutical industry, namely to using actynomycete lysate for preparing external nail care products. Using actynomycete lysate of the strains Actinomyces R/3.88, L/1.89 or a mixture thereof for preparing external nail care products. A method for improving the appearance of the nails.

EFFECT: using the described actynomycete lysate improves the health and appearance of the nails.

2 cl, 1 tbl, 2 ex

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmacological and cosmetic industry, namely to a dermatological agent. The dermatological agent containing antler deer's dry blood plasma, Mumiyo, D-Panthenol, Sea buckthorn oil and additives in certain proportions.

EFFECT: above dermatological agent possesses higher bioavailability and biological activity, as well as extends the range of similar products.

2 cl

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to medicine. An antimicrobial composition contains chlorhexidine and pentane-1,5-diol, wherein the amount of chlorhexidine makes 0.000001 to 5 wt %, while the amount of pentane-1,5-diol makes 1 to 75 wt %. The composition is applicable for local administration; it contains a carrier and a gelling material.

EFFECT: group of inventions enables applying the composition for non-therapeutic disinfection, in treating skin infections.

Anti-wrinkle agents // 2503443

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to chemical-pharmaceutical industry and represents wrinkle-reducing agents containing compounds presented by general formula (1), stereoisomers or pharmacologically acceptable salts thereof, wherein R1 represents a hydrogen atom or a linear or branched alkyl group with 1-8 carbon atoms; R2 represents -SH, -SO3H, -S-X2, -SO-X3, -S02-X4, X2-X4 represents carbon atoms or aliphatic hydrocarbon groups with 1-8 carbon atoms independently, R3 represents a hydrogen atom or an acyl group with a linear or branched alkyl chain with 1-8 carbon atoms, R4 represents a phenyl, tolyl, ethyl phenyl, propyl phenyl, butyl phenyl, pentyl phenyl, hexyl phenyl, methoxyphenyl, ethoxyphenyl, propyl oxyphenyl, butyl oxyphenyl, pentyl oxyphenyl, hexyl oxyphenyl or biphenyl group, m is equal to 0, n is equal to the integer 1 or 2.

EFFECT: invention provides preparing the compounds and cosmetic products possessing the anti-wrinkle effectiveness.

10 cl, 11 ex, 2 tbl, 7 dwg

FIELD: medicine.

SUBSTANCE: invention refers to methods of treating early enamel loss. The presented method of treating or reducing early enamel caries involves the dental application of an effective amount of a dental composition wherein the dental composition has a main formulation containing dicalcium phosphate, wherein the dental composition additionally contains arginine in the free or salt form, and an effective amount of fluoride, wherein arginine is found in the amount of 2 to 10 wt % of total weight of the dental composition.

EFFECT: composition used in the method possess an ability to increase enamel demineralisation that enables treating or reducing early enamel caries.

3 cl, 1 tbl, 4 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to dentistry and may be used in the orthopaedic treatment of the patients with partial and/or complete denture defects using removable laminar dentures. A method involves making the removable laminar dentures, taking the oral hygienic measures, cleaning the removable laminar dentures. Ozonised olive oil is applied on an internal surface of the prosthetic basis that is followed by applying the prosthesis on the denture defect for 10-30 minutes. The prosthesis with ozonised olive oil applied on the internal surface of the basis is attached once a day for 8-16 days.

EFFECT: method provides more effective patient's adaptation to the removable laminar dentures due to the polycomponent mechanism of ozonised olive oil in the same environment with no negative side effects.

2 ex, 2 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely gerontology, and may be used for preventing the premature human ageing. That is ensured by adding the food ration with min. 50 g of the functional foodstuff 'Samarskiy Zdorovyak' per one intake - with breakfast or lunch or dinner with underlying diet therapy.

EFFECT: method enables providing more effective prevention of the premature ageing due to enhancing the body adaptability, reducing hyperlipidemia, stimulating fat splitting, reducing abdominal obesity and normalising blood pressure.

FIELD: medicine.

SUBSTANCE: invention refers to method for producing a chromogenic shelf fungus complex, wherein milled shelf fungus is wetted in ratio (0.5-1.5) - (3.5-4.5), frozen at temperature minus 16±3°C for 1-4 hours, settled for 1-2 hours at temperature 65-75°C, filtered; the filtrate is acidified in 25% hydrochloric acid to pH 1.0-2.0, mixed, settled for 12-15 hours and filtered.

EFFECT: declared invention provides higher yield of the chromogenic shelf fungus complex and higher antioxidant activity.

1 tbl, 20 ex

Antiherpetic agent // 2502504

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to agent possessing antiviral action, and may be used for treating herpes infections, including lip sore. The given agent contains the ingredients, wt %: a solution readily permeable through biological membranes of soapy amphiphilic complex of high-polymer RNA of Saccharomyces cerevisiae and oleic acid (as an interferon inducer) - 49.96; Vaseline oil - 20; Tween-80 - 17; Emulsifier T-2 - 13; Chlorhexidine Bigluconate - 0.04.

EFFECT: preparation shows high antiherpetic activity, good tolerability and ability to reduce a recurrence rate considerably.

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to neurology, and may be used for treating spasticity accompanied by improved consciousness in the patients in the vegetative state. That is ensured by administering Xeomin (botulinumtoxinA free from complexing proteins) into the spastic muscles of all the extremities and related body segments regardless of the contractions in total dose of 400-1300 units. The dose shall not exceed 24 unit/kg of body weight in 1-3 stages. The stages follow at least every 3 days. Every 1-day stage involves administering 5-50 units in each accessible muscle or muscle group with the maximum tone in max. total dose 500 units dissolved in 12.5 unit/ml. The injections are distributed uniformly along the area without electromyography. The following courses are similar if observing spasticity and/or if clinically reasonable. The length of one course is up to 3 weeks.

EFFECT: method enables improving the therapeutic effect in the vegetative states.

3 ex, 3 tbl

FIELD: chemistry.

SUBSTANCE: invention relates to field of cosmetology and represents preparation for removing nail polish, which contains organic solvent, cosolvents and target additives characterised by the fact that propylene glycol is used as organic solvent, mixture of ethyl alcohol, ethyl acetate, propylene carbonate, dimethyl glutarate, isopropyl alcohol are used as cosolvents, and mixture of glycerol, gelatin, jojoba oil and denatonium benzoate is used as target additive, with components in preparation being in specified wt % ratio.

EFFECT: invention ensures creation of preparation for removing nail polish without unpleasant smell, with wide spectrum of efficient effect on different types of manicure polishes, as well as characterised by restoring impact on nails, and impossibility of accidental intake as food.

1 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to - arthrology, physiotherapy, balneology. The method involves physical methods of therapy, therapeutic exercises, massage, acupuncture and phytotherapy. The patients are trained to give a self-massage of the knee joints additionally during the resort therapy and after the termination of the rehabilitation. From the 1st to 10th day of the therapeutic course patient's knee joint is exposed to polychromatic polarised light at 20 cm for 6 minutes. The patients take 10 iodine-bromine baths at temperature 37°C for 10 minutes. From the 1st to 5th therapeutic days, the patients do combined therapeutic exercises; their lower extremities are massaged manually for 10 minutes. From the 6th to 15th days, the knee joints are exposed to sinusoid modulated currents (SMC) at modulation frequency 100 Hz, at a depth of 50 - 70%, current intensity to moderate vibration for 7 minutes. From the 6th to 10th days, the braking acupuncture follows by giving a 1-2-minute massage of the points 10RP, 9RP, 36E, 34E by introducing a needle for 30 seconds and by giving a point massage of cheng-fu, cuan, yang-lin-cuan, zu-sang-li, wei-yang, cheng-shan, chung-feng, hun-lun, nei-ting. The patients take a herbal infusion. From the 11th to 15th days, the knee joints are exposed to decimetric waves (DMW). That is followed by a hydro-massage of the lower extremities and lumbar region for 15 minutes up to 3 atm. Thereafter, the 10-minute post-isometric relaxation of the quadriceps muscle of thigh is applied. The patients do the complex of weight reduction exercises and take the herbal infusion. From the 16th to 20th day, the mud applications on the knee joints are prescribed at temperature 42°C for 30 minutes. If suffering gonarthrosis, the patients do the complex of therapeutic exercises. That is followed by the paravertebral vacuum therapy of the vertebral column. The 10-minute knee joint traction is applied. The patients take 20 g of the herbal infusion.

EFFECT: method recovers the joint mobility, improves the exercise tolerance of the lower extremities.

1 tbl, 2 ex

FIELD: food industry.

SUBSTANCE: invention relates to biotechnology and fodder production, in particular, to a method for production of a fodder additive for prevention of anima and bird mycotoxicosis. The method envisages mechanochamical treatment of the raw stock components with further granulation of the produced mixture. The components are represented by a mixture containing a mineral sorbent, hydrolised lignin and fodder yeast cell walls. The mechanochemical treatment consists in milling individual components in rotary vortex mills with an embedded particle classifier of in the components mixing and treatment in the presence of at least one compound enzyme preparation affecting hydrolised lignin residual polysaccharides and yeast cell walls polysaccharides.

EFFECT: method allows to produce a compound additive having a wide range of effects with improved efficiency of fodder mycotoxins binding, stimulating the immune system and preventing malfunctions in the animal and bird digestive tract; at the same time, combined usage of hydrolised lignin, fodder yeast and a mineral sorbent as a preventive agent with animals allows to minimise the sorbent application side effect, recover the digestive tract homeostasis and normalise metabolic indices.

15 cl, 12 tbl, 3 ex

FIELD: medicine, oncology, amino acids.

SUBSTANCE: invention relates, in particular, to the development of an antitumor preparation based on natural substances. Invention relates to an amino acid preparation comprising at least one modified essential amino acid obtained by treatment of amino acid by ultraviolet radiation (UV) at wavelength 250-350 nm for 12-80 h at temperature 15-30oC or with ozone at temperature 15-25oC. The modified amino acid has no toxicity for health cells. Also, invention relates to a method for preparing such preparation. Invention provides the development of an antitumor preparation based on modified amino acids and expanded assortment of antitumor preparations being without cytotoxicity for normal cells.

EFFECT: valuable medicinal antitumor properties of preparation.

8 cl, 4 tbl, 2 dwg, 4 ex

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