Method for prevention of premature human ageing

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely gerontology, and may be used for preventing the premature human ageing. That is ensured by adding the food ration with min. 50 g of the functional foodstuff 'Samarskiy Zdorovyak' per one intake - with breakfast or lunch or dinner with underlying diet therapy.

EFFECT: method enables providing more effective prevention of the premature ageing due to enhancing the body adaptability, reducing hyperlipidemia, stimulating fat splitting, reducing abdominal obesity and normalising blood pressure.

 

The invention relates to medicine, namely to therapy and gerontology, and for the prevention of premature aging of the human body.

There is a method of reducing biological age with abdominal obesity (RF patent 2407520, priority from 15.06.2009). The invention relates to medicine, namely to gerontology, endocrinology, and can be used to reduce pathologically increased biological age of the patients with abdominal obesity. To do this, assign rational dosed static and dynamic exercise, daily swimming in the pool at least 30 minutes a day and Metformin at a dose of 850 mg 2 times a day. The course of treatment is 7 weeks. The proposed combination of techniques of treatment to align biological and chronological age, which increases the quality of life of these patients.

There is a method of reducing biological age (hereinafter BV) in arterial hypertension abdominal obesity with dyslipidemia (RF patent 2407504, priority from 15.06.2009). The essence of the proposed method lies in the fact that patients are prescribed complex, including a low-calorie diet, calculated in kcal formula for women of different age and weight. Also prescribe rationally dosed static and dynamic physical loads, Lucaya morning hygienic gymnastics, of preventive and curative gymnastics, fractional exercise throughout the day, daily swimming in the pool. The use of all components of the complex allows to normalize BV for 7 weeks of treatment.

However, the effectiveness of treatment as mentioned above is insufficient. The above treatments do not exclude premature aging of the organism as a whole, do not increase the adaptation capacity of the organism and do not reduce the impact on the body of negative external factors.

The present invention is directed to the achievement of the technical result consists in increasing the efficiency of prevention of premature aging by expanding adaptive capacity, reducing hyperlipidemia, the stimulation of lipolysis, increase antioxidant function, reduce abdominal obesity, blood pressure.

This technical result is achieved by the fact that in the known nutritional therapy (RF patent 2407504) is additionally introduced into the daily diet of functional food (FRR) at a daily dose of not more than 150 g in equal doses three times a day, not more than 50 g per dose: Breakfast, lunch, and dinner.

The method is as follows. In the bowl with a capacity of 250 ml asleep 5 tablespoons (50 g) of dry product (powder in videosi) and add to taste sugar or honey. Diluted to the desired consistency liquid with a temperature not exceeding 60°C (hot milk, water, dairy products, juices etc), mix thoroughly and cover. After a minute, the product is ready for use. The specified product is added to the basic diet three times a day - Breakfast, lunch, and dinner.

The frequency of pathological processes in old age due to the effects of the aging process. In elderly and senile age significantly increases the role of internal factors in the development of several pathological processes of the circulatory system, pulmonary system, gastrointestinal tract, CNS (Central nervous system) and others).

On the other hand, various diseases are themselves factors that accelerate the aging process, serve as prerequisites for the signs of premature (accelerated) aging.

The testing method was used FRR "Samara hefty", RF patents №2403802, 2403805, 2405380.

Used functional food is a product of special purpose natural origin, which is designed for regular use and is intended to fill the lack in the body energy, plastic or regulatory food substances. Exerting a regulating effect on physical function is, biochemical reactions and psychosocial human behavior, such products maintain physical and mental health and reduce the risk of disease. Additional introduction of functional food "Samara provides a balanced, certain quantitative and qualitative composition (RF patents: 2403802, 2403805, 2405380) developed in the doses and mode provides effective preventive effects on the human body in the long term by optimizing the functioning of the quality of peptides.

The quality of functioning of the peptides depends on the quality of supply and use balanced functional foods.

Peptides are composed of 20 amino acids, including essential, which are connected to each other in the manner typical of cells of the immune system.

In addition to amino acids, there are more and mineral substances, trace elements and vitamins (including b vitamins and PP) in biologically bound form, which contributes to their better functioning. This allows the peptides to exert specific functions of tissues, designed to restore the normal functioning of cells, organs and body systems.

An important principle of gentiletti is also balanced the ity of the energy value of food intake and energy expenditure of the body.

In the development of pathological processes and premature aging plays a role not only energy imbalance, and the imbalance of the individual components of food, as with age, reduced tolerance to carbohydrates and fats. Functional food "Samara big guy" has proved the following distinctive properties:

1. Preventive effect FRR "Samara big guy" is implemented through hepatoprotective liver function by reducing hyperlipidemia, the stimulation of lipolysis, increase antioxidant function, reduce abdominal obesity, blood pressure.

2. 150, FRR "Samara hefty" contains the amount of folic acid and selenium, micro and macro elements, vitamins and fiber more than twice the per diem amount of the body in old age and senility.

3. Dominance effects FRR "Samara big guy" on the mechanisms of the modern theories of active longevity is in the system impact and stabilization of metabolic processes.

4. Registered 3 times (in the experiment) reduction of blood corticosteroids (11-ACS) when using FRR "Samara big guy".

Treatment diet therapy FRR "Samara provides a method of suppressing Svobodnaya the activity, invasive detoxification of the human body, optimizing neurogenic regulation of vascular tone. The constant use of functional foods with a high content of antioxidants, vitamins and minerals, especially zinc and selenium, is a reliable tool in the prevention of premature aging. It is advisable to include in systemcomplete treatment and prevention diet, therapeutic and preventive nutrition functional food "Samara provides outpatient, inpatient and sanatorium treatment.

During 2009 the Federal state institution "Russian scientific center for restorative medicine and balneology" University have conducted clinical trials on the topic: "assessment of the effectiveness of diet, therapeutic and preventive nutrition "Samara big guy" based on his study of detoxification, prebiotic, hepatoprotective activity on metabolism in patients, and the study of neurogenic regulation of circulation and variability blood pressure in patients", fully confirmed the achievement of the technical result.

The results of our study also confirm the literature data about the participation of bifidobacteria in holesterinova the exchange. Thus, the observed patients with intestinal dysbiosis was accompanied by hypercholesterolemia. The inclusion in the diet of patients with functional food "Samara big guy" helped restore the dynamic balance of the microflora of the colon and/or growth sacharolytica microflora, which led not only to improve the functional state of the intestine, but also had a hypocholesterolemic effect in patients with high cholesterol levels.

Thus, the results of clinical studies of the effectiveness of functional food "Samara hefty" with botanicals in the proposed doses allow us to recommend them as diet, prebiotic and functional foods in the prevention of premature aging of the organism.

Contraindications to the use of functional food "Samara hefty" not found.

Additional introduction of functional food "Samara provides a balanced, certain quantitative and qualitative composition (RF patents: 2403802, 2403805, 2405380) developed in the doses and mode provides effective preventive effects on the human body in the long term by optimizing the functioning of the quality of peptides a comp the tra actions aimed at korregirovannye energy processes, strengthening compensatory, adaptive and regulatory mechanisms, the normalization of reactivity to exogenous and endogenous stimuli.

Inclusion in the medical complex functional food product based on the FRR "Samara hefty" contributes to a more pronounced decrease in weight, BMI (body mass index), and reduction of waist circumference. Weight loss is associated with low calorie whole grain cereals, which contain large amounts of fiber and nutrients and are part of the FRR. Weight reduction is very physiological, while the body receives a large amount of useful biologically active substances. The weight loss and contributes to some greater antihypertensive effect, mainly in respect of GROUNDS (systolic blood pressure).

The positive effect of additives on lipid profile showed a decrease of total cholesterol, LDL (cholesterol low-density lipoprotein) and increase HDL cholesterol (the cholesterol high-density lipoprotein). This is due to the positions of the lipid distress syndrome, with increased choleresis, restoration of motor-evacuation function of the gallbladder, reducing neurogenic tone of the sphincter of Oddi, which provides a greater flow of bile in Kish is cnik and creates all metabolic conditions for the normalization mechanism of the enterohepatic circulation of bile acids and digestive system. Improving the function of the liver, silymarin (contained in restorable, part of the FRR "Samara hefty) inhibits the synthesis of cholesterol by reducing the activity of microsomal gidroksimetil-COA reductase inhibitors; beta-glucan (as contained in oatmeal oats) increases the level of deoxycholic acid in the liver, which contributes to low levels of liver cholesterol and preventing its reabsorption, normalizes bowel for timely evacuation of bile acids and prevents constipation.

Thus, therapeutic effect FRR is implemented through hepatoprotective liver function by reducing hyperlipidemia, the stimulation of lipolysis, increase antioxidant function, reduce abdominal obesity, blood pressure. The obtained data allow us to consider the use of the FRR as adequate non-drug method for increasing the efficiency of treatment of patients with arterial hypertension with metabolic syndrome, which provides the effect on the basic pathogenesis of the metabolic syndrome: overweight, hyperlipidemia, arterial hypertension.

Among diseases of the cardiovascular system, which is one of the main reasons for the development of premature aging, it is necessary to allocate in the first place atherosclerosis and arterial hypert is SIU.

The essence generegulatory theory is that the primary changes in the aging process is associated with shifts in the regulation of the genome, i.e. the system generegulatory mechanisms.

Found that muscle activity is a source of powerful stimulating effects on metabolism, has a mobilizing effect on reflex and humoral mechanisms of the internal environment.

In the future, there is a reduction of muscle activity occurs reflexively influence the working muscles internal organs. This provides an adequate ratio between the intensity of muscle activity and metabolism of the tissues, the condition of the major functional systems.

During aging attenuated metabolic processes, reduces the intensity of redox reactions. This feature is largely due to decreased activity of enzyme systems, providing the use of oxygen by tissues.

It is established that under the influence of systematic physical exercise metabolic processes intensify, increasing the efficiency of oxygen use, reduced oxygen cost of work performed. Active motor mode has a positive effect on the CNS (Central nervous system), significantly improves the status is of the cardiovascular system, increases the adaptability of the circulatory system to physical activity, resistance to stressful situations.

Additional introduction of functional food "Samara provides developed in the doses and mode provides effective normalization of blood pressure and metabolic disorders in humans in the long term due to the hepatoprotective liver function by reducing hyperlipidemia, the stimulation of lipolysis, increase antioxidant function, reduce abdominal obesity, increased stress resistance, as well as the normalization of the functional operation of the system neuroelectronic regulation of the arteries. The use of functional foods "Samara hefty allows you to control the amount of free radicals, promotes detoxification of the tissues, elasticity of vessels of all calibers, improve blood flow and circulation, normalization of neurogenic mechanisms of regulation of blood flow and blood pressure.

Identified the following SEVEN EFFECTS in the use of the FRR in the recommended modes: 1) geroprotective, 2) desintoxication, 3) prebiotic, 4) hepatoprotective, 5) probiotic, 6) antioxidant effect 7) continuous synthesis of enzymes and hormones.

Therapeutic and prophylactic effective the application of functional food "Samara provides confirmed in the conclusion on the results of the clinical evaluation of the effectiveness of diet "Samara provides for the treatment and prevention of patients gastroenterology and cardiology profile approved by the Director of the Federal state institution Russian scientific center for restorative medicine and balneology of the Ministry of health and social development of the Russian Federation, academician of the RAMP, Professor A.N. Owned, 22.03.2010.

The way to prevent premature aging of the human body, characterized in that on the background diet is additionally introduced into the diet of functional food "Samara provides not less than 50 g per reception - Breakfast, or lunch, or dinner.



 

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