Method for treatment of suppurative wound |
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IPC classes for russian patent Method for treatment of suppurative wound (RU 2257211):
Ointment for treatment of burn, suppurative and infected wound of different etiology and method for treatment of burn, suppurative and infected wound / 2256441
Invention relates to curative ointments with anti-inflammatory effect and with biostimulating properties for treatment of burns, suppurative and infected wounds of different etiology and to a method for treatment above said diseases using the ointment said. The proposed ointment comprising bee wax and greasy basis comprises colophony additionally. As greasy basis the ointment comprises butter and vegetable oil in the following ratio of components, wt.-%: bee wax, 20-30; butter, 30-40; vegetable oil, 15-25; colophony, 15-25. Method involves applying ointment by thin layer 0.5-3 mm on dense cotton fabric, its applying to damaged site, keeping and removing ointment with change of bandage 1-3 times per 24 h for 3-14 days. Method provides enhancing the therapeutic effectiveness of ointment due to significant acceleration the healing process of suppurative wounds and insidious furuncles being the ointment doesn't cause irritating effect.
Agent for treatment of suppurative wound / 2254120
Invention relates to medicinal preparations used for treatment of suppurative wounds. Invention involves applying boric acid (powder) and multi-component ointments on water-soluble base (Laevomecolum or Laevosinum) taken in the ratio 1:10 and used for treatment of suppurative wounds. Invention provides the development of agent exhibiting the expressed antibacterial, dehydrating and necrolytic effect.
 Method for therapy and control for the process of treating scars as a result of acne vulgaris / 2252796
One should apply an applicator onto affected parts of skin that contains 5-aminolevulinic acid at concentration of 5-20%. After keeping and removing the applicator it is necessary to irradiate with light at wave length being 630 ± 10 nm and energy density of 10-1200 J/sq. cm. Control should be carried out due to evaluating the concentration of photosensitizer at affected parts of skin due to fixing fluorescence ranges at all basic stages of photodynamic therapy. The method enables to adjust skin relief and achieve scars' whitening and their regression.
Method for manufacturing remedy for prophylaxis of wound suppuration / 2252749
The innovation deals with manufacturing remedies to prevent wound suppuration based upon polymeric matrix and antimicrobial substance due to mixing components in solution, forming the film to obtain a powder-like medicinal form by providing the safety of antimicrobial activity of medicinal preparation. The obtained remedy is completely biodestructed in the body and requires no repeated operation on its removal after the end of tissue regeneration processes.
Ointment for treating burns and other skin diseases / 2252018
The present innovation deals with preparing ointments to be applied at treating both surface and deeply penetrating cutaneous burns and other skin diseases, as well. Composition of the suggested ointment includes, weight%: 45…67% food sunflower oil, 15…37% food olive oil, 1…2% Calendulae officinalis extract, 0.8…1.8% labdanum, 2.5…8% colophony, 6.5…11.5% white bee wax, 0.7…1.8% the main bismuth gallate and 0.7…1.8% camphor. The suggested ointment is highly efficient for rapid and successful treatment of burns III and IV degree. It should be also applied for treating shin's ulcer and, also, in gynecology - for treating inflammation of uterine cervix.
 Medium in case of ultrasound cavitary treatment of wounds / 2250104
The present innovation deals with treating different wounds. The suggested perfluorocarbon emulsion is being used as the medium in case of ultrasound treatment of wounds. Moreover, the enhancement of reparative processes is observed in the wound along with accelerated wound healing due to development of perfluorophages in area of inflammatory process and to higher gas saturation of perfluorocarbon emulsion against other media applied before. The emulsion under the action of low-frequency ultrasound obtains other properties (increased specific weight, increased fluidity, higher wettability of purified surface, the presence of abrasive properties) necessary for achieving technical result. All these measures, thus, enhance reparative processes in the wound because low-frequency ultrasound raise to a higher power the action of perfluorocarbon emulsion both regarding ultrasound purification and its curative action upon wound.
Method for producing preparation for photodynamic therapy / 2246314
Method involves destruction and hydrolysis of alga taken among the group including: laminaria, zooster and focus followed by separating the cytoplasmatic fraction and addition of food acid polyvalent metal salt. Then correction of acidity is carried out to obtain pH = 5-7 followed by drying and conversion of fraction to form useful for storage by sterilization or freezing, or drying, or preserving. The food acid polyvalent metal an aqueous solution is added preferably in the amount 0.75% of preparation mass. Invention provides expanding functional capacity of the preparation with respect to stimulation of processes in healing wounds and burns, regeneration of post-traumatic damages, oncoprotecting and photo-sensitizing activity with respect to cancer cells at maximal absorption of light radiation in the region 630-770 nm.
Method for preventing after-burn scar-type esophageal stenosis / 2246312
Early bougienage should be carried out, moreover, additionally, starting since the 4th - 7th d it is necessary to apply ozonized vegetable oil per 1 t.s.p 4 times daily 20-30 min before meals every day, the course should last for about 1-1.5 mo, moreover, as vegetable oil one should apply either olive, sunflower of sea-buckthorn one.
Ointment of antiphlogistic and wound-healing action (variants) / 2246310
The present innovation deals with curative ointments of antiphlogistic and wound-healing action and could be applied for treating hemorrhoid, burns, bruises, fractures, wounds, chronic bronchitis, polyarthritis, periarthritis, radiculitis, trophic ulcer and psoriasis. Three variants of ointments have been suggested. They contain oily extract of plant components and, also, honey, mumiye, propolis and bear oil. This innovation enables to widen the assortment of ointments of antiphlogistic and wound-healing and the range of curative action upon a body.
 Agent "argolit" for treatment of infected wounds / 2245151
Invention proposes an agent for treatment of infected wounds that comprises zeolite of Kcholinskiy deposit that represents zeolite powder modified with silver with particles size 17-20
Method for treating the cases of allergic diseases / 2250773
Method involves introducing autologic mesenchyma trunk cells as a single intravenous drop dose or in the amount of 1 mln cells per 1 kg of patient body weight.
 Method for treating the cases of non-operable cardiologic patients / 2250772
Method involves using mononuclear autologic marrow fraction containing 6-9x104 mesenchyma cells per 1 ml or autologic mesenchyma trunk cells. The cells are separated from brain bioptate in the amount of 106 cells/kg of patient body mass. The preparations are intracoronarily introduced in fractions at a rate of 3-5 ml/min into the right coronary artery. The introduction is also carried out in intra-arterial mode in jets or in drops.
 Method for preventing postsplenectomic syndrome in experiment / 2247567
Embryonic spleen should be sampled, washed in nutritive medium № 199 to be placed into fresh medium № 199 to obtain homogenate in teflon homogenizer followed by centrifuging; then one should isolate the upper, medium and inferior layers, suck off medium layer and the upper part of inferior layer; the cell mixture obtained should be diluted in nutritive medium № 199 to be then introduced by injections into mesentery of small intestine or rectus muscle of abdomen. The present innovation favors the activation of immune system in patients undergone splenectomic operation and in those in case of surgical immunodefficient state due to high functional and regenerating activity of transferred embryonic splenic cells.
 The method of treatment of patients with neurotic and somatoform disorders / 2239441
The invention relates to medicine, namely to psychiatry and pharmacotherapy of borderline mental disorders
The method of producing drug for increasing the resistance of the organism of animals / 2237485
The invention relates to the technology of obtaining biologically active compounds to increase the resistance of the organism of animals
 The method of producing mielopid / 2232584
The invention relates to medicine, namely to methods of producing biologically active preparations from bone marrow of animals
 The method of treatment of locally advanced cancer of the organs of the oral cavity and pharynx / 2231355
The invention relates to medicine, namely to Oncology, and can be used for the treatment of patients with malignant tumors of the organs of the oral cavity and pharynx
A method of treatment of peritonitis / 2226118
The invention relates to medicine, and is intended for the treatment of peritonitis
 The method of treatment of locally advanced cancer of the larynx / 2211042
The invention relates to medicine, namely to Oncology, and can be used to treat cancer of the larynx
Agent for treatment of conjunctiva inflammatory disease, bacterial damage of retina capsule / 2257210
Invention proposes a new agent for applying in therapy of inflammatory diseases of eye anterior site, namely, the silver-containing preparation "Argogel" "Argogel" represents argovite dispersion in polyethylene oxide gel. The preparation shows an antibacterial and virucidal effect and gel base shows additional keratoplastic effect. Invention can be used in therapy of conjunctivitis and retina suppurative ulcers.
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FIELD: medicine, surgery. SUBSTANCE: method involves every day covering a wound with an agent comprising of pig spleen homogenate and oxygenated with perfluorane taken in the following amounts: 100 g of pig spleen homogenate and 10 ml of oxygenated perfluorane. Invention promotes to accelerating sanitation of suppurative wounds due to activation of topical immunity and activation of regenerating processes. Invention can be used in treatment of suppurative wounds. EFFECT: improved treatment method of wounds. 2 ex
The invention relates to medicine, namely to surgery, and can be used for the treatment of acute and chronic local infection. It is known that for the treatment of purulent wounds applies the homogenate of porcine spleen (a Method of treatment of purulent wounds. The patent of the USSR to the invention SU 1801488 A1, et al. Shushpanov, M.a.aliyev). The homogenate of xenoculture accelerates the removal from the wound toxico-infectious agents, metabolic products of resorption of detritus, accelerates the development of granulation and epithelization of wounds, improves local immunity. However, the homogenate of porcine spleen does not have the property of improving kislorodolechenie tissue inflammation zone. One of the important factors that contribute to the improvement of wound healing, many authors consider the oxygenation zone of inflammation (Ratner GL, 1974; Zinchuk WU, 1995; Paramonov B.A., 2000; Hant BECAUSE, 1974; Ufbink D.T., 1994), which can be stimulated by various factors, including the use of perfluorocarbon compounds (Mokrushin V.I., 1995; Osipov A.P., Krupkin V.I., 1997; Krylov K.M., Chiguanco E.N., 1999). The use of perfluorocarbon emulsion stimulates the formation of tissue macrophages (perforation), which have increased phagocytic activity (Lutsevich EV, Kalinin MR, Poltoratskaya N.A., Dolgatov GD 2001). However, despite the advantages, this method of treatment has the disadvantages. So, when using dressings with perftoran in the first phase of wound healing positive effect was not observed, and the total time of healing of the wounds remained large (Osipov A.P., 1997, 2001; Krupkin V.I., 1997). As a prototype we have used the method for the treatment of septic wounds according to the patent of the USSR to the invention SU 1801488 A1, et al. Shushpanov, M.a.aliyev from 15.03.93, The method prototype is as follows: Fence spleen produce meat immediately after slaughter with respect to the reimbursement, the spleen is placed in a sterile plastic bag and immediately taken to the hospital where after removing the capsule slurry cut it into small pieces, and pound in a mortar to obtain a homogeneous mass. Then make applique homogenate of purulent wounds and ulcers. The homogenate of xenoculture accelerates the removal from the wound toxico-infectious agents, metabolic products of resorption of detritus, accelerates the development of granulation and epithelization of wounds, improves local immunity. But the homogenate of porcine spleen does not have the property of improving kislorodolechenie tissue inflammation zone. The use of perfluorocarbon emulsion stimulates the formation of tissue macrophages (perforation), which have increased phagocytic activity (Lutsevich EV, Kalinin MR, Poltoratskaya N.A., Dolgatov G.D. 2001). However, this method of treatment has drawbacks. So, when using dressings with perftoran in the first phase of wound healing positive effect was not observed, and the total time of healing of the wounds remained large (Osipov A.P., 1997, 2001; Krupkin V.I., 1997). The purpose of the invention is the reduction of terms of treatment of purulent wounds and ulcers by activation of local immunity and tissue oxygenation, which accelerates as rehabilitation and regenerative processes. The method of treatment of purulent wounds and trophic ulcers, claimed as the invention is as follows. For the implementation of the proposed method produces therapeutic application of cell mass consisting of a homogenate of porcine spleen with the addition of perftoran on the entire wound surface, the thickness of the overlay means is 2-3 mm. Applications are changed every day. Therapeutic cell mass prepared as follows: Fence spleen produce meat immediately after slaughter in compliance with the rules of asepsis, the spleen is placed in a sterile plastic bag and immediately take to the clinic, where washed spleen is cut into 5-6 pieces. The tissue of the spleen is placed in the mixer, sterilized with 0.5% chlorhexidine, and crushed, resulting in a homogeneous mass (homogenate). 12 the aces to the intended use of the bottle with perftoran from the freezer transferred to a refrigerator with a temperature of +4° C. Immediately before use "is reheated in warm water until the temperature of the alleged introduction (+33-36°C), then Oxygenium apparatus Bobrov. To obtain the necessary funds to the homogenate of porcine spleen add oxygenated perftoran in the following quantities: 100 g of the homogenate of porcine spleen and 10 ml oxygendemanding of perftoran. The combination of these products provides the article concludes that effect. Examples of specific implementation method: Example 1. Nosikova L.D., born in 1955 was admitted to the hospital 12.11.03, with a diagnosis of diabetes of the 1st type, severe, stage of decompensation, diabetic foot syndrome, ischemia-gangrenous form, wet gangrene of the toes of the left foot, complicated by purulent thatcame dorsal and plantar surfaces. 13.11.03, operation transplacentally amputation of the left foot, the opening of the suppurative Saakov, necrectomy. Despite the complex conservative therapy, the wound was not cleared, the effect of the treatment was not. Therefore treatment with applications of homogenate of porcine spleen add oxygendemanding of perftoran. After seven applications the wound was cleansed, appeared "lush" granulation, which gave the possibility to make free plastic skin wound surface mesh flap. Perez is right flap stuck the patient was discharged home. Example 2. Sulamangalam P.M., born in 1931 was admitted to the hospital 25.10.03, with a diagnosis of diabetes of the 2nd type, moderate, decompensation, diabetic foot syndrome, neuropathies positive form, trophic ulcer of the right foot. In the heel area of the ulcer size 6×4,5×1.5 cm, cloth forming the bottom of the ulcer, gray, places with purulent-necrotic tissue. Due to the lack of effect of conventional therapies with 03.11.03, treatment applications homogenate of porcine spleen and oxygendemanding of perftoran in the following quantities: 100 g of the homogenate of porcine spleen and 10 ml oxygendemanding of perftoran. After 5-6 applications ulcer was purified from necrotic tissue, appeared bright granulation, the edges began epithelialization. 16.11.03, the ulcer healed completely, the patient was discharged home. Signs, distinctive features of the prototype: using homogenate of porcine spleen in combination with perftoran in the following quantities: 100 g of the homogenate of porcine spleen and 10 ml oxygendemanding of perftoran. The usefulness of the invention: The method allows to increase the efficiency of the treatment is achieved accelerated cleansing and wound healing by increasing local immunity, improve tissue oxygenation zone of inflammation treatable chronic local processes,with no effective conventional treatment methods, promotes rapid cleansing of the wound microflora, amid sluggish course of the inflammatory process, after application is a significant increase in phagocytic activity of cellular elements, the development of lymphocytic reaction and enhancing regeneration. The source of information The patent of the USSR to the invention SU 1801488 A1, Shushpanov, M.a.aliyev from 15.03.93, prototype. The method of treatment of purulent wounds, consisting in the application of the wound surface with a homogenate of porcine spleen, characterized in that the wound daily cover means consisting of a homogenate of porcine spleen and oxygendemanding of perftoran in the following quantities: 100 g of the homogenate of porcine spleen and 10 ml oxygendemanding of perftoran.
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