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Compositions for cosmetic preparations, means for personal hygiene, components of purifying action, food additives, methods for their obtaining and application

Compositions for cosmetic preparations, means for personal hygiene, components of purifying action, food additives, methods for their obtaining and application
IPC classes for russian patent Compositions for cosmetic preparations, means for personal hygiene, components of purifying action, food additives, methods for their obtaining and application (RU 2251405):
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FIELD: cosmetology, food industry.

SUBSTANCE: the present innovation deals with compositions for cosmetic preparations, means for personal hygiene, purifying components, biocidal components, functional food and food additives. Due to these compositions one should introduce bioactive glass containing SiO2, CaO, P2O5 and Na2O, not obligatory, into the objects mentioned. Moreover, the present innovation deals with methods to obtain and apply the compositions mentioned. It enables to obtain cosmetic products capable to withstand bacterial infection.

EFFECT: higher efficiency.

134 cl, 19 ex, 5 tbl

 

The technical field

The present invention relates to new compositions for cosmetic products, personal care products, cleaning agents, biocidal agents, functional food and dietary supplements. Using such compositions in cosmetic products, cleaning agents, personal care products, biocidal agents, functional, nutritional agents and supplements introduced biologically active glass. The present invention also relates to methods of producing and using these compositions.

Prior art

Preservatives are a necessary and important ingredients that ensure the sustainability and safety of various products. There are a number of issues relating to the well-known preservatives. Many of them have undesirable influence on the products that have preservatives, or on a living subject or a subject to whom such products. Other substances of this type are relatively expensive and do not provide any other actions, in addition to the preservative. Many of these substances are not in fact effective preservatives. Other substances of this type have an undesirable effect on the texture and taste characteristics of the product. There is a need to develop improved preservatives.

is there an urgent need to create ingredients which can safely and usefully be used in products that have antibacterial, antifungal, antiviral, ion-troop, anti-inflammatory and/or pH properties and/or living objects or subjects for which designed these products. There is a need in the ingredients that demonstrate one or more of the specified properties.

The use of bioactive glass for other purposes, e.g. for orthopaedic rehabilitation, described Larry L., and Jon K. West in "Biological Applications of Bioactive Glasses", Life Chemistry Reports, 1996, v.l3, pp. 187-241, and on the contents of this work are referenced in this application.

The invention

The authors of the present invention have found that with the introduction of bioactive glass into various cosmetics last acquire a exceptional high quality involving useful preservative effect. The authors also found that bioactive glass acts as a preservative against a large number of standard household and industrial cleaning agents. In addition, some compositions of bioactive glasses have excellent cleaning properties and greatly enhance the cleaning properties of traditional household and industrial cleaning agents. In addition, applicants have found that some of the bioactive composition from UCLA represent a useful functional food products and dietary supplements or can be entered in these products. Moreover, it was found that some compositions of bioactive glass function as an excellent preservative of food.

It should be added that the composition of the present invention can be formed, as indicated in this application, so that they are improved and useful properties like antibacterial, antiviral, antifungal, ion-releasing, anti-inflammatory and pH-regulating properties.

Description of the invention

Bioactive glass is a sodium-calcium-phosphoro-silicate glass. Used in the text, the term “bioactive glass” can refer to bioactive glass, derived from fine-grained melt and/or methods of Sol-gel technology. In addition, the term “bioactive glass” can be used in relation to the water extract of the bioactive glass obtained from fine-grained melt and/or method the Sol-gel technology.

In the present invention is used bioactive glass, preferably containing 40-96% of the mass of silicon dioxide (SiO2), 0-35 wt% sodium oxide (Na2O), 4-46% of the mass of calcium oxide (Cao) and 1-15 wt% of phosphorus oxide (P2About5). In the proposal refer to bioactive glass, typically a composition based on silicon dioxide, which are able to established the th hydroxycarbonate Apatite (NSA). According to a more preferred variant of the considered glass contains 40-60 wt% of silicon dioxide (SiO2), 5-30 wt% sodium oxide (Na2O), 10-35 wt% of calcium oxide (Cao) and 1-12% of the mass of phosphorus oxide (P2About5). These oxides may be present in the system in the form of solid solutions or mixed oxides or mixtures of oxides.

In addition to the oxides of silicon, sodium, phosphorus and calcium in the composition may be introduced Caf2In2About3, Al2O3, Mao and K2O. the Preferred spacing of content In a2About2is 0-10% of the mass. The preferred spacing of the K2About is 0-8% of the mass. The preferred interval content of MgO is 0 to 5% of the mass.

Generally, bioactive glasses have the following composition, expressed in weight percents:

Component Content, % mass
SiO2 40-90
CaO 4-45
PA2About 0-35
P2O5 2-16
Caf2 0-25
In2About3 0-4
To2O 0-8
MDO 0-5

Below are more preferred is sustained fashion the composition of bioactive glasses, expressed in mass percent:

Component Content, % mass
SiO2 40-68
CaO 5-30
Na2O 10-35
P2O5 1-12

The present invention relates to formulations, which may include ionic metal compounds, as gN2, CuO and ZnO, or other antimicrobial salt without any limitations, with ions of silver, copper and zinc. These metals may be present in the form of their nitrates or acetates. The preferred spacing of the contents of these salts is 0-15 wt%. The present invention also encompasses formulations that do not contain metal ions.

The most preferred glass is a Bioglass®™ (trade name University of Florida), having a composition comprising about 45% of the mass of silicon dioxide, about 24.5% of the mass of sodium oxide, about 6% of the mass of phosphorus oxide and about 24.5% of the mass of calcium oxide.

Another preferred material is hydroxyapatite. For some applications, the preferred material can serve as porous glass obtained by the method of Sol-gel technology.

For many preferred embodiments of the present invention,the preferred material is fine-grained, unbound bioactive glass. This glass is a material in the form of small, discrete particles and not in the form of a fused matrix, or in the form of a mesh or fabric (woven or non-woven) made of fiberglass. It should be noted that in some conditions the discrete particles of the present invention acquire a tendency to grip under the influence of electrostatic or other forces, but they can still be considered as unbound particles. The preferred size of the considered particles measured using SEM or by scattering of laser light, has a value of less than 90 microns; more preferably less than 20 microns; more preferably less than 5 microns and most preferably less than 2 microns, although for different applications can be used particles of various sizes.

The preferred spacing of the particle size of the bioactive glass depends on how and where to apply. Can be used particles with a size less than 1000 microns and 2 microns. Particles of such small size usually provide the advantages of the present invention, without causing unwanted immune responses.

Not limited to a specific theory, it is assumed that there is a complex relationship between the nature of the ion emitted from the glass, the number of such ions, the speed of the ejecta is, the pH value of the environment, on the one hand, and appropriate antimicrobial or anti-inflammatory response, on the other hand. The considered effect is observed both in terms of particles of bioactive glass, and solutions containing particles of glass. In accordance with this, in the following compositions and their applications can be used fine particles and/or solutions containing particles of bioactive glass.

Large particles of bioactive glass does not have a noticeable antimicrobial properties. However, small particles of bioactive glass and highly porous bioactive glass in a noticeable degree show these properties. Bioactive glass has antibacterial properties and is an effective substance in relation to, for example, Staph. Aureus, Staph. Epidermidis and various species of streptococci. These bacteria may be present inside and on the surface of the skin. Consider antimicrobial properties are amplified in the aquatic environment. Without consideration of the specific mechanism of action, we can assume that this action is a result of, inter alia, significantly increased the bioactivity of small particles, which leads to an increase in the pH of the environment. The resulting properties, covering a wide bactericidal effect when odnovremenno.menyu biocompatibility with tissue, makes a variety of formulations containing small particles of bioactive glass, resistant to microbial contamination and particularly suitable for skin contact.

The degree of antimicrobial activity increases with decreasing particle size. The preferred particle size, to a certain extent, depends on the expected microbial exposure and the desired purity of the formulations containing bioactive glass. So, for example, formulations containing particles of bioactive glass size of about 20 microns, are quite active. But for long-term preservative effect or maintain a high degree of purity can be used, particle size less than five microns, which is measured using SEM or laser scattering.

When using highly porous bioactive glass instead of, or together with small particles of bioactive glass pore size is 0-500 μm, preferably 10-150 μm, and more preferably 50-100 μm. The degree of porosity of such glass is 0-85%, preferably 30-80%, and more preferably 40-60%. Porous bioactive glass can be obtained, for example, by introducing capable of leaching substances in the composition of the bioactive glass and its subsequent leaching from the glass. Suitable substances capable of Vyselki aniu, well known to the person skilled in the art, include, for example, sodium chloride and other water-soluble salts. The particle size of leachables roughly equal to the size of the resulting pores. The relative number and size of particles capable of leaching substances determine the degree of porosity of the material obtained. In addition, as discussed herein, the porosity can be achieved with the use of sintering and/or regulation loop with the obtaining of material with a specified pore size and internal pores.

In addition, antimicrobial and anti-inflammatory compositions based on aqueous extracts of bioactive glass can be formed by placing the bioactive glass into the solution, ensuring sufficient time for its dissolution, such as a period of weeks or more, and filtering the dissolved glass particles. The used solvent can be removed by evaporation to obtain a solid material having antimicrobial properties. The resulting composition can be used in cases when it is advantageous to take steps for removal, destruction or prevention of the action of microbes, including bacteria, viruses or fungi, but not limited to that in the case of a cosmetic re is eptor, cleaning agents, functional food and food preservatives.

Stcloader.exe composition can be obtained in several ways, ensuring the formation of particles of glass obtained by melting, methods, Sol-gel technology and sintering. Sintered particles can be present in the glass samples obtained by Sol-gel technology, in unreacted form or a form obtained from the pre-reacted alloy.

It is preferable to obtain steklokompozita of the respective melts. Glass from the melt is usually prepared by mixing granules of oxides or carbonates, melting and homogenizing the mixture at a high temperature, for example at 1250-1400°C. the Molten glass may be subjected to grinding to obtain fine-grained material.

In each of the methods of obtaining it is desirable to use a chemically clean glass, especially when a specified glass is used for the preparation of materials suitable for simultaneous local application. Particles of bioactive glass can be obtained using the method based on melting and grinding, which is previously described in U.S. patent No. 5204106 and referenced in the present description. In the case when you want a specific particle size to receive them can IP olsavica the sifting process. In order to achieve optimal sterility glass particles may be subjected to ultrasonic cleaning, Packed in siphons and sterilized by the action of gamma radiation.

Fine-grained biologically active material used in the present invention, may be prepared in known in the field methods described, for example, in U.S. patents№№ 4159358, 4234972, 4103002, 4189325, 134171544, 4775646, 4857046 and 5074916. So, for example, raw materials (for example, SiO2, CaO, Na2O and P2O5)located in the container from plastic Nalgen®™, stirred with a ball mill for four hours. Then the mixture is subjected to melting in a platinum crucible at a temperature of 1350°and homogenized for 24 hours. Molten glass is poured in distilled, deionized water to obtain a glass Frit. On the other hand, while pouring the glass on the moving rollers can be obtained glass ribbon. The resulting Frit or tape may be subjected to grinding, which is carried out in several ways. According to one of these methods, the Frit or the tape is crushed in a mortar with pestle and passed through ASTM sieve to obtain particles of the desired size. On the other hand, the Frit or tape can be crushed using a ball or a flying-off of the mill.

Bioact the Noah glass can be made using the stages of drying, which can be drying in ColorAnimation condition. Drying in ColorAnimation the state to be used instead of, or in conjunction with drying in dry conditions, provides a composition with a much larger average pore size for a given level of the content of SiO2. In addition, drying in okolobankovskih conditions allows to achieve a higher speed resorption compared with bioactive glass, obtained by conventional Sol-gel method. For example, when tested in vivo, it was shown that more than 50% of the Sol-gel material obtained in this way, resorbed over eight weeks. While 4555 bioactive glasses obtained from the melt, not recarbonate for eight weeks. It has been suggested that glass, containing more than 55% of silicon dioxide, are not bioactive.

Used in the text, the term “drying in okolobankovskih conditions” refers to drying in conditions close to the borders of the two phases in the phase diagram at a temperature and pressure sufficient to produce bioactive glass with macro-porous structure, i.e. such a pore structure which ensures obtaining bioactive glass. So, for example, drying in okolobankovskih conditions can be dried in a state close to the water line, as illustrated by the traditional diagrams is th phase state (or other liquids, for example, methanol, ethanol, acetone, liquid CO2, benzene and the like). As the result of these manipulations on sealing the drying chamber with the aim of deviation of drying conditions on the equilibrium line and changes in relative humidity (normal values up to 98%), regulation duration coloradosee drying temperature, drying the possibility of dramatic changes of the pore size of the resulting bioactive glass. So, for example, enhancing the sealing of the drying chamber during the drying tends to increase the relative humidity and the diameter of the pores. The process temperature coloradosee drying also can be changed as the result of drying in the presence of water. When using other liquids other than water as listed above, the drying process can be accelerated and may be considerably increased the pore size of the gel.

The Sol-gel method is any process involving the use of Sol-gel system for the preparation of bioactive glasses. Getting glass Sol-gel method generally includes a step of synthesis of inorganic matrix by mixing alkoxides of metals in solution with subsequent hydrolysis, gelation temperature and low temperature (200-900° (C) firing with obtaining glass. It is known that the glass obtained in this Sol-gel method are the high initial specific surface area (SSA) compared with glass, obtained from the melt or porous glass from the melt. The resulting material has a nanometric porosity and SSA has in the range of 50-400 m2/, Glasses obtained by Sol-gel method, do not contain sodium. Because of this when contacting such materials with an aqueous solution implemented other mechanisms of dissolution than in the case of bioactive glass, obtained without the use of techniques Sol-gel technology.

Usually bioactive glasses obtained by Sol-gel method, have the following composition, expressed in weight percents:

Component Content, % mass
SiO2 49-90
CaO 5-42
P2O5 1-12

A more preferred composition based bioactive glasses obtained by Sol-gel method, has the following composition, expressed in weight percents:

Component Content, % mass
SiO2 49-72
CaO 5-35
P2O5 5-9

Glasses obtained by Sol-gel method, easily react with aqueous solutions, because it is characterized by a high value of SSA (taimela very large surface area, where can flow reaction system glass/solution). When immersed in an aqueous solution of the bioactive glasses obtained by Sol-gel method, react, releasing the soluble silica, calcium and phosphate anions. With increasing concentration of calcium and phosphate anions to the limit of saturation for Nar is formed on the surface of the mineralogical enriched Nar layer, which includes a Sol-gel derived bioactive glass and the surrounding surface (for example, hard and soft tissues of the human).

So, for example, to obtain a Sol-gel bioactive glasses can be used in the reaction mixture containing tetraethoxysilane (TEOS), triethyl phosphate (TER) and calcium nitrate. For this purpose you can also use the alkoxides of calcium, titanium, zirconium, magnesium, aluminum, iron, and potassium. Specialist in the art should understand that they can be used and other appropriate ingredients. In addition, can be used aerogel. When using aerogel to achieve a larger pore size and increasing the capacity to absorb instead of drying in okolobankovskih conditions apply increased pressure.

Sol-gel processes that use stage drying in okolobankovskih conditions, provide final products with increased pore size and very b the structure of education NSA in gels as low and with high silicon dioxide content. Such compositions provide a more rapid formation of the NSA than other gels when exposed to SBF (Simulated Body Fluid, Kokubo, T. And others, J.Biomed. Mater. Res., 24, 721-34, 1990) or physiological fluids. Drying in okolobankovskih conditions also ensures more homogeneous gels, which can be heated to elevated temperatures while maintaining the large diameter pores. This allows for improved quality control of the final product, for example to regulate its absorption, homogeneity and physical structure. For example, the Sol-gel compositions obtained without the use of stage drying in okolobankovskih conditions, is not able to provide adequate absorption at high contents of silicon dioxide. In contrast, the use of drying technologies in okolobankovskih conditions allows to obtain a gel with a great capacity for absorption even at high contents of silicon dioxide. In addition, the Sol-gel glass are more homogeneous materials, other than the Sol-gel glass, and have a uniform distribution of calcium.

Described drying technology can be used to obtain the Sol-gel bioactive glasses of all types. For example, this technology can be used to obtain a Frit, films, monoliths, Askov, coatings, fibers, woven materials, materials, pattern and composites.

For the multipurpose use of the Frit can be crushed to form particles with a very wide size interval, for example, from 2 μm to 1 mm, the Monolith can be formed to obtain complex shapes, for example, various implants. Powders can be formed in the form of spherical particles with the size from submicron to several hundred microns. Such compositions can find use, for example, in the restoration of bones and other orthopedic applications in the delivery of medicines, the treatment of hypersensitive teeth, as well as in the remineralization of tooth structure, the healing of burns and wounds.

Not limited to a particular theory, it can be assumed that drying in okolobankovskih conditions reduces the capillary forces within the porous structure of the gel, which ensures the formation of large pores. The gels represent the mesh of small colloidal particles. These grids include voids that form pores in the porous channels in the final glass composition. It is assumed that the moisture present on stage coloradosee drying, favors the reaction between two particles stacks in their narrow and increases the strength of the neck and the “backbone” of the gel structure, h is about reducing the drying shrinkage of the structure and at the same time produces a gel with large pores.

On the other hand, due to the pressure of the liquid pressure drop in the pores and channels of different size meets the following expression:

ΔP=2γcosθ/r,

in which γ refers to the fluid pressure, θ - contact angle, and r is the radius of the pores and the porous channels. During drying, the pressure drop, ΔR, promotes the densification of the grid, which makes possible the destruction of the porous structure and the shrinkage of the gel as the evaporation of the liquid. It is assumed that kolorowanka drying allows the evaporation of the liquid inside the porous structure under conditions close to equilibrium in a wide temperature range. Within the channels and then set the vapor pressure of the liquid, corresponding to conditions of high heat, which prevents shrinkage and destruction of the gel structure and ensures the production of a material with large pore size. Bioactive glass Sol-gel derived bioactive glass and/or aqueous extracts of bioactive glass can be entered in various cosmetics, cleansing agents, functional food, food supplements and other products listed below.

Cosmetics

The overall presentation

The present invention provides for obtaining new cosmetic compositions comprising bioactive glass. In modern production processes considered is emich drugs usually controlled bacterial contamination of products, in airtight containers, however, after opening of such containers bacteria, fungi and/or mold can get into cosmetic preparations. To minimize this possibility in cosmetics often impose different antibacterial agents. However, such antibacterial agents often have a negative impact on the user of cosmetics, for example irritate the skin.

The purpose of the present invention is the development of cosmetic formulations, which, in contrast to existing cosmetics, have the ability to resist bacterial infection without such adverse effects like skin irritation.

According to one embodiments of the present invention in cosmetic formulations may be administered bioactive glass to reduce the likelihood of bacterial contamination, including contamination by bacteria, fungi and/or mold. Such cosmetic compositions may contain water extracts of bioactive glass and/or particles of bioactive glass.

In accordance with one of the embodiments of the present invention cosmetic formulation includes fine-grained bioactive glass with an average particle size less than 10 microns. According to another technical solution used fine-grained bioactive glass has a particle size less than 5 microns, pre is respectfully less than 2 microns. Preferred cosmetic products are creams, preparations for makeup, lipsticks, lotions and ointments, as in this case microbiocidal effect of bioactive glass reinforced under the influence of moisture contained in such preparations. However, the bioactive glass can add practical in all existing cosmetics to improve their resistance to pollution. Accordingly, the cosmetic product may be a material on a liquid basis or on a basis other than liquid. For example, the cosmetic formulations may include creams, lotions, lipsticks, tools for makeup and infusions.

In accordance with one of the embodiments of the present invention provides bioactive glass, intended for use as a preservative of perishable products. Such perishable products may constitute, for example, cosmetic and/or pharmaceutical preparations. According to another technical solution of the present invention provides a preservative containing bioactive glass. This preservative containing bioactive glass may be added or incorporated into cosmetic formulations.

Cosmetic formulation of the present invention may contain bioactive is flowed in an amount up to 95% by weight of the total formulation, especially up to 70%, better yet up to 50% or 40% and even more preferably up to 30% by weight of the cosmetic formulation. For some formulations, the upper limits of the content of the additive is 7 wt% or 5 wt%, whereas for the other formulations are particularly preferred upper limit is 3% of the mass. The lower limits of the content of the additive may be 0.01% by mass, especially of 0.1 wt%, whereas the most preferred values of the lower limit is 0.5 wt% and 1 wt. -%

According to one of preferred embodiments of the invention the cosmetic formulation contains proton solvent. According to another embodiment of the cosmetic formulation contains bioactive glass of the following components present in these quantitative intervals, expressed in mass %: 40-60% SiO, 10-30% CaO, 10-35% Na2O; 2-8% P2O5, 0-25% CaF2; 0-10%2About3; 0-8% Off2About; and 0-5% Mao.

The cosmetic formulations of the present invention may well be used to protect bioactive glass, the drug does not contain irritating the skin cytotoxic and allergen-producing chemical preservatives. In addition, the use of bioactive glass, as a result of its antibacterial and inhibits inflammation action is achieved by the additional, nourishing effect. Anti-E. the effects of bioactive glass are particularly useful application in the means of care of skin by reducing irritation, itching, redness and rash.

In special cases, it is especially desirable to add a preservative of the present invention in the preparations, which were guarded with standard preservatives, in order to achieve a synergistic effect.

Bioactive glass has the ability to react with aqueous solutions (for example, human sweat, moisture, biological fluid), and implemented such biological effects as the impact on antimicrobial/antibacterial characteristics, shielding of UV-radiation, anti-inflammatory characteristics, education mineralogical film and therapeutic selection inorganic ions. These effects are considered favorable for many cosmetic applications, and this paper describes some examples of cosmetic formulations that can be used for inclusion in the cosmetic product of the bioactive glass and/or Sol-gel derived bioactive glass.

Bioactive glass forms hydroxycarbonate layer (NSA) on such protein-containing surfaces, such as hair, skin, nails and teeth. This NSA layer may reduce the sensitivity of teeth to seal/to thicken the nails, to protect the skin and to modify the structure.

Bioactive glass and/or Sol-gel proizvodstvyennoe glass can be an effective material in terms of absorption and scattering of visible and UV light, what makes these materials attractive for soft focusing and sunscreen applications.

According to one embodiments of the invention cosmetic products include Sol-gel derived bioactive stele. Sol-gel derived bioactive glass is an extremely porous material and is effective in scattering of visible and UV light. The scattering of visible light is important to gently focusing cosmetic products that are designed to scatter light falling on the skin, resulting in wrinkles on the skin become less noticeable. The scattering of UV light is an important factor for protection from the sun. Thus, the Sol-gel derived bioactive glass are effective materials for scattering of UV light in the UVA and UVB regions of the solar spectrum, providing a soft focus effect.

In addition, Sol-gel derived bioactive glass reacts with aqueous solutions with the formation of a solution with a high concentration of calcium, phosphate anions and soluble silica. When the saturation of this solution on the surrounding human tissue is formed mineralogical, Nar-enriched layer. Thus, it can be expected that Sol-gel derived bioactive glass will be an effective material for makotoko arousih products since such glass efficiently scatters visible light, and precipitation mineralogical layer has a skin tightening effect and thereby hides wrinkles.

It should also be noted that in addition to the bioactive glass in cosmetic formulations can be administered antibiotics.

The addition of antibiotics in cosmetic products containing bioactive glass, is especially useful for formulations intended for local use.

Methods of obtaining.

The present invention also provides a method of obtaining cosmetic compositions comprising bioactive glass. In such formulations add or enter an effective antimicrobial amount of a bioactive glass. The term “effective antimicrobial amount of bioactive glass” refers to the amount of bioactive glass with an appropriate particle size, which is sufficient for effective prevention or control microbial contamination. The number and size of particles of bioactive glass, introduced in the cosmetic formulation may vary depending on the desired duration of action and purity of the drug, and the nature of microbial contamination. The term “effective antimicrobial amount of bioactive glass” can also refer to a quantity of an aqueous extract of bioactive glass, the residual for effective prevention or control microbial contamination. The term “effective antimicrobial amount of” bioactive glass may also refer to a combination of fine-grained bioactive glass and water extract of the bioactive glass used to effectively prevent or control microbial contamination.

Bioactive glass may be added or included in cosmetic formulations, for example, using such methods or techniques, as the usual mix of low, moderate and even high speed mixing. To ensure the required homogeneity should ensure adequate mixing system. Preferably, during the mixing and stirring were excluded excessive aeration and used a low shear rate. In addition, can be used antiflatulent to prevent clumping of the particles. For this purpose can be used and other methods or combinations thereof, such as mixing, dispersion, Association and/or emulsification. Mixing can be achieved, for example, using standard mixing devices. Mixing and stirring may be carried out using, for example, a blade stirrer.

Unexpectedly, it was found that for many major cosmetic formulations homogeneous mixing with bioactive glass flows easier than others the traditional inorganic powders, for example, powders of titanium dioxide and zinc oxide.

Bioactive glass may be added or included in almost all known cosmetic formulations. According to the applicants, the bioactive glass is suitable for insertion into any of the currently developed cosmetic compositions. According to one embodiments of the invention the bioactive glass may be in the form of fine powder. According to another embodiment the bioactive glass may be an aqueous solution, obtained from fine-grained bioactive glass. According to another embodiment of the invention, the bioactive glass may be a combination of fine-grained bioactive glass and an aqueous solution of the bioactive glass.

The inventors have unexpectedly found that when mixing the bioactive glass with oil formed cream. Similarly, when mixing the bioactive glass of water suddenly formed cream. The cream obtained by mixing the bioactive glass with oil or water, has a consistent, homogeneous texture, suitable for cosmetic formulations.

The inventors have unexpectedly discovered that the combination of bioactive glass with standard creams to protect the skin gives the skin a pleasant view and creates a pleasant amalakite feeling, compared the Yu with the same action cream which is used in the absence of bioactive glass. Not limited to a particular mechanism, it is assumed that the bioactive glass has an affinity to oils and water and a protein substance that is consistent with the observed unexpected effect of education of the cream is soft, homogeneous consistency of the bioactive glass and oil. Thus, the bioactive glass can be used for efficient processing of oily/greasy skin.

Bioactive glass and Sol-gel derived bioactive glass have many desirable characteristics, can improve the cosmetic products. However, the difficulties are that there must be the formation of a cosmetic product, wherein the bioactive glass and/or Sol-gel derived bioactive glass remain directionspanel (passive) when packaging and become reaktsionnosposobnykh (active), when applied to the human body.

Bioactive glass and Sol-gel derived bioactive glass react with aqueous solutions, but are inert materials when immersed in anhydrous liquid. So, bioactive glass and Sol-gel derived bioactive glass can be formed in the form of liquid preparations, pastes, gels or creams, which is the anhydrous material, but having a solubility in water (or alausi the UIS permeable materials). In this case, the bioactive glass remains directionspanel when immersed in anhydrous liquid, paste, gel or cream, but is activated when applied to the human body and is able to react with sweat, moisture and/or vadose holding biological fluids.

According to one embodiments of the present invention the bioactive glass and/or Sol-gel bioactive glass for cosmetic products is used with distribution systems containing two separate vessel (e.g., similar to the distribution systems used for epoxy resins). Bioactive glass and/or Sol-gel derived bioactive glass are formed with anhydrous liquid, paste, cream or gel in one vessel, while the aqueous liquid, paste, cream or gel are in the second vessel.

According to another embodiment of the invention the bioactive glass and/or Sol-gel bioactive glass is mixed with anhydrous liquid, paste, cream or gel that when applied to the body evaporate or metabolize to hit the skin. Anhydrous liquid, paste, cream or gel that protects the bioactive glass inside cosmetic packaging, are removed after application on the body, allowing the bioactive glass to react with sweat, moisture and/or other aqueous biological environments.

<> According to another embodiment of the invention the desirable properties of the bioactive glass and/or Sol-gel derived bioactive glass are acquired when using the aqueous extract of the bioactive glass. Bioactive glass and/or Sol-gel derived bioactive glass can react with the aqueous solution until it is saturated with calcium, phosphate anions and soluble silica. Then this solution should be filtered to create a buffer with an appropriate pH value and then add in cosmetic formulations to create cosmetic products of the present invention. Pursuant to this embodiment, the formulation may contain water of cosmetic ingredients, because there is no solid bioactive glass or Sol-gel derived bioactive glass, able to react.

In many cosmetic applications, it is desirable that the product had a pH in the range of 5-8. However, maintaining such pH values in the presence of bioactive glass in aqueous suspensions difficult because the glass continuously reacts with the solution, increasing the pH value. The inventors have found that only about 1% of citric acid can serve as an effective buffer for bioactive glass and provide a more neutral pH values during longer receiving the Oia in water suspension. The result differs from the effect added to these suspensions such standard buffers as buffers on the basis of HCl that don't provide maintain the pH within the desired time periods. Thus, the use of citric acid is one of the preferred methods of buffered aqueous solutions of bioactive glasses. Bioactive glass are particularly useful for aqueous formulations in the case when the recipe accordingly bufferinput to maintain the pH at a value close to neutral, and when the bioactive glass cover water repellent material, preventing its reaction in the recipe.

In accordance with another embodiment of the invention the bioactive glass and/or Sol-gel bioactive glass can be formed in the form of a dry material containing other ingredients such as coloring agents and perfumes, and then packaged in small packets or sachets for use as a disposable cosmetic products for skin care, hair or nails. This dry form may be a powder.

Listed in Table I materials can be mixed with a bioactive glass with obtaining stable compositions.

Table I

Raw materials for the additives in bioactive glass

Raw materials

Incromectant AQ

Promyristyl PM-3

Dennl DPG-2B

Transcutol CG

Octyl methoxycinnamate

Grodafos N3N

Triethanolamine

Mental anthranilate

Mineral oil

Incrodet TD7C

Polyderm PPI SiWI

PEG2 Oleamine

Crodafos CAP

Plantaren APB

Polyderm PPI SiWS

Finsolv TN

Crodasinic 0

Dermol B-246

GE 1202

Crovol A-40

Crovol A-70

GE SF 96 350 cps

Probutyl 14

Foamtain CABG

Dermol M5

Cetyl ether, PPG 10

PEG 7 Glyceryl cocoate

d-Limonene

Oleth-3

Stepanquat ML

Lauryl ammonium

Incromectant LQ

Tergitol NP-9

Coco hydroxy sultaine

Crodesfca SL-40***

POE20 Sorbitan monooleate

Propylene glycol

Ethanol

Na Laureth-2 sulfate

Isostearate sorbitol

Glycerin

Procetyl AWS

Crodafos SG

Glycerox 767

Running amide DEA

Oil str

Abil EM-90

Listed in Table 2, the materials were mixed with the Sol-gel derived bioactive glass with obtaining stable compositions.

Table II

Raw materials for the additives in the Sol-Rel-derived bioactive glass

Raw materials

Dermol M5

Cetyl ether BCP 10

PEG 7 Glyceryl cocoate

d-Limonene

Oleth-3

Stapanquat ML

Lauryl ammonium

Incromectant LQ

Tergitol NP-9

Coco hydroxy sultaine

Crodesta SL-40

POE20 Sorbitan monooleate

Propylene glycol

Ethanol

Na Laureth-2 sulfate

Isostearate sorbitol

Glycerin

Procetyl AWS

Crodafos SG

Glycerox 767

amide DEA

Oil str

Incromectant CABG (45%)

Promyristyl PM-3

Abil EM-90

Dermol DPG-2B

Transutol CG

Octylmethoxycinnamate

Crodafos N3N

Three is tanolin

Methylanthranilate

Mineral oil

Incrodet TD7C

Poliderm PPI SiWI

PEG2 Oleamine

Crodafos CAP

Plantaren APB

Poliderm PPI SiWS

Finsolv TN

Crodasinis 0

Dermol B-246

GE 1202

Crovol A-40

Crovol A-70

GE SF (350 350 cps)

Probutyl 14

Bioactive glass, including Sol-gel derived bioactive glass can be combined with the anhydrous cosmetic ingredients to obtain a stable, non-irritating cosmetic formulations. In Table III are examples of such anhydrous ingredients.

Table III

Anhydrous cosmetic ingredients designed for use with bioactive glass

Cosmetic applicable glycols, including the following substances, but not limited to:

Glycerin

Propylene glycol

Butyleneglycol

Hexyleneglycol

2-Methylpropanol

Cosmetic applicable alcohols, comprising the following substances, but not limited to:

Ethanol

Isopropanol

N-Propanol

Lauric alcohol

Alerby alcohol

Cosmetic applicable esters, comprising the following substances, but not limited to:

Isopropylmyristate

Isopropyl

Oil str

Three capret/kaprilat glycerin

Di capret/kaprilat propylene glycol

Esters of sorbitol

The diesters of dibasic acids

The bottle : the Kie applicable ethoxylated materials, includes the following substances, but not limited to:

Ethoxylated fatty alcohols

Ethoxylated fatty acids

Ethoxylated esters of sorbitol

Ethoxylated glycerides

Cosmetic applicable propoxycarbonyl materials, including the following substances, but not limited to:

Propoxycarbonyl fatty alcohols

Propoxycarbonyl fatty acids

Esters propoxycarbonyl fatty alcohols

The ethoxylated propoxylated

Cosmetic applicable anhydrous innogene surface-active compounds, including the following substances, but not limited to:

Complex phosphate esters

Sulfate esters

The carboxylates

Salts of fatty amines

Salts of Quaternary nitrogen

Cosmetic applicable mineral, vegetable and animal oils and fats. Cosmetic applicable silicones, including the following substances, but not limited to:

Dimethicone

Simethicone

Cyclomethicone

Ethoxylates and propoxylate dimetikona

Cosmetic applicable fluorocarbons and their derivatives, including the following substances, but not limited to:

Zanily

Fluorocarbon alcohols

Cosmetic applicable propellant, including the following substances, but not limited to:

The PCC is n

Bhutan

Pentane

Isobutane

BORE, CFC, HCFC

Bioactive glass, including Sol-gel derived bioactive glass can be combined with the anhydrous and aqueous cosmetic ingredients to obtain a stable, non-irritating cosmetic formulations. Anhydrous and aqueous cosmetic ingredients can be applied using the distribution system of the two compartments. In Table IV lists examples of such anhydrous and aqueous cosmetic ingredients.

Table IV

Anhydrous and aqueous ingredients that can be used with the use of the distribution systems of the two compartments.

Cosmetic applicable glycols, including the following substances, but not limited to:

Glycerin

Propylene glycol

Butyleneglycol

Hexyleneglycol

2-Methylpropanol

Cosmetic applicable alcohols, comprising the following substances, but not limited to:

Ethanol

Isopropanol

N-Propanol

Lauric alcohol

Alerby alcohol

Cosmetic applicable esters, comprising the following substances, but not limited to:

Isopropylmyristate

Isopropyl

Oil str

Three capret/kaprilat glycerin

Di capret/kaprilat propylene glycol

Esters of sorbitol

The diesters of dibasic acids

The bottle : the Kie applicable ethoxylated materials, includes the following substances, but not limited to:

Ethoxylated fatty alcohols

Ethoxylated fatty acids

Ethoxylated esters of sorbitol

Ethoxylated glycerides

Cosmetic applicable propoxycarbonyl materials, including the following substances, but not limited to:

Propoxycarbonyl fatty alcohols

Propoxycarbonyl fatty acids

Esters propoxycarbonyl fatty alcohols

The ethoxylated propoxylated

Cosmetic applicable anhydrous innogene surface-active compounds, including the following substances, but not limited to:

Complex phosphate esters

Sulfate esters

The carboxylates

Salts of fatty amines

Salts of Quaternary nitrogen

Cosmetic applicable mineral, vegetable and animal oils and fats. Cosmetic applicable silicones, including the following substances, but not limited to:

Dimethicone

Simethicone

Cyclomethicone

Ethoxylates and propoxylate dimetikona

Cosmetic applicable fluorocarbons and their derivatives, including the following substances, but not limited to:

Zanily

Fluorocarbon alcohols

Cosmetically applicable amides, including the following substances, but not limited to:

Diethanolamin the s fatty acids

Monoethanolamide fatty acids

Dimethylaminopropylamine fatty acids

Cosmetically applicable polymers, comprising the following substances, but not limited to:

Polyalkene

Polyoxyethylene

Polyoxypropylene

Polyamides

Polyethers

Polyurethane

Cellulosic materials and their derivatives

The polyacrylates

The polymethacrylates

Polysiloxane

Cosmetically applicable copolymers

Cosmetically applicable bases for cosmetic formulations comprising these substances, but not limited to:

Emulgirujushchie waxes

Softening gels (Lubrajels)

Zileli (Zilgels)

Cream add gloss on the basis of str

Absorption bases

Bioactive glass, including Sol-gel derived bioactive glass may also be used in conjunction with cosmetic ingredients that can evaporate soon after application on the skin. Such combinations can be used to create sustainable, non-irritating cosmetic formulations. Table V lists the examples of cosmetic ingredients that can evaporate after application on the skin.

Table V

Evaporating ingredients

Cosmetic applicable alcohols, comprising the following substances, but not limited to:

Ethanol

Isopropanol

N-Propanol

Bottle : the ski applicable esters, includes the following substances, but not limited to:

The ethyl acetate

Butyl acetate

Cosmetic applicable ethoxylated materials, including the following substances, but not limited to:

Etokxidiglicol

Cosmetic applicable silicones, including the following substances, but not limited to:

Cyclomethicone

Dimethicone

Cosmetic applicable ketones, including the following substances, but not limited to:

Acetone

Methyl ethyl ketone

Cosmetic applicable aliphatic compounds, comprising the following substances, but not limited to:

n-Alkanes

Branched alkanes

Permitieron connection (Permethyls)

Aerosol propellant

Cosmetic applicable fluorocarbons, chlorofluorocarbons, hydrofluorocarbons and hydrochlorofluorocarbons, including the following substances, but not limited to:

Aerosol propellant

One aspect of the present invention will become better understood after considering the following, not limiting the scope of the invention examples relating to cosmetic products and personal hygiene means, which can be applied bioactive glass.

Categories of cosmetic products and personal hygiene

The present invention provides for obtaining new Rotz the tour for a large number of cosmetic products and personal hygiene, includes the following products, but not limited to: means for care when tanning and pigmentation of the skin, diaper, baby towels and hand towels; baby powder and body powder, and tissues against rash; pads for care (for brass)preparations; make-up; swabs, cosmetic pads and contour pencils; means for prevention and control of acne; facial cleanser facial, cleanser with toning and exfoliating action and means for removing make-up; means for wetting the face, means for skin care for preventing wrinkles means of skin care around the eyes, lotions, hand and body lotions; preparations for the care of feet; anti-irritation of the skin; anti-microbial, antiseptic, antibiotic tools and first aid; bath and shower soap in the form of bars; liquid and gel-based cosmetic products and bath salt; shampoos and tools to help detangle hair; mousse hair gel to wash your hair and spray for hair styling; antiperspirants and deodorants in the form of powders, creams, ball packaging, aerosols and pencils; lotions and after shave; shave in the form of a cream, gel, powder and soap; means of depilation, epilation and preparations for bleaching the hair in the form of a cream, wax and powder; toothpastes; subn the e elixirs; wigs and onlays made of artificial hair; shoulder pads; means to hide freckles, preparations for instillation into the eye; and means for processing contact lenses.

Pigment products

The present invention provides new formulations with which the bioactive glass is introduced in different varieties such pigmented products, such as the products sold under the trademarks of Bain de Soleil Banana Boat, Coppertone, Fruit of the Earth, Good Sense, Hawaiian Tropic, Kiss My Face, Neutrogena, as well as products manufactured by qualified and well-known manufacturers.

Usually the active ingredient pigment products is dihydroxyacetone (DHA).

Traditional formulations of pigmented products include water, glycerine, dihydroxyacetone, octylpyrimidine, butyleneglycol, cetyl alcohol, DISTEARYL ether methylglucose and GPR-20, stearyl alcohol, crosspolymer acrylates/C10-30 alkylacrylate, aloe-Vera gel, cocoa butter, DEA-cetilistat, Dimethicone, disodium EDTA, DMDMH the as eucalyptus oil, perfumes, literallayout, iodopropionic, lanolin, mixed silicate of magnesium aluminum stearate PEG-100, Polysorbate 60, sodium metabisulfite, sorbic acid, steareth-20, xanthan resin, as well as various vitamins, minerals, fruit and plant extracts.

In addition, pigmented products may also contain about the but or more of the following substances: acetate isoceteth-3, BCP-1 Trideceth-6, bisabolol, prostart PEG-20 methylglucose, triglyceride Caprylic/capric acids, unsaponifiable products, benzyl alcohol, butylparaben, benzoate C12-15 alcohol, caramel, carbamate/acrylate copolymer, carbomer, ceteareth (cetyl-stearyl ether)-20, Zetec(cetyl ether)-10, ceteth-2, satellitesatellite, citric acid, diazolidinylurea, dimetridazole, dipropyleneglycol, disodium EDTA, emulsifying wax, etokxidiglicol, ethylparaben, imidazolidinethione, isoceteth-20, isopropyl, melanin, methylglycol-20, methylparaben, octylmethoxycinnamate, panthenol, PEG-7 literallayout, petrolatum, Phenoxyethanol, a copolymer of a polydimethylsiloxane-ether BCP/IPDI, Polysorbate 20, Polysorbate 80, propylene glycol, propyl paraben, silicone, sodium PCA, sorbitol, stearic (stearyl ether)-2, stearic acid, tocopherylacetate, triethanolamine and Hamamelis.

With the present invention receive new recipes pigment products by introducing a bioactive glass into a combination of any of the above ingredients. Moreover, the bioactive glass can function as a pigment. In addition, bioactive glass can topiramate various metals, including without specific limitations iron, cobalt and/or manganese with achieving the desired pigmentation.

<> Cosmetics for care in the sun

The present invention covers a new recipe, with which the bioactive glass is introduced into various brands of products under the sun, for example in market products brands A-FIL, Alba Botanica Aloe Vera 80, Ambrelle, Bain de Soleil Banana Boat, Biosun, Blue Lizard, Brite-Life, Bull Frog, Coppertone, DuraScreen, Eita Block, the ashes of esoterica, Flents, Fruit of the Earth, Good Sense, Hawaiian Tropic, Jason, Kiss My Face, L.A. Tan, Lily of the Desert, Native Tan, Nature's Gate, Neutrogena, No Ad, Off, Panama Jack, PreSun, Sea and Ski, Sunblock Shade, Sol Bar, Sunbrellas, Sun Splash, Ti-Screen, Water Babies, and products produced by high-quality and well-known manufacturers.

Pigment formulations and formulations for care in the sun, including bioactive glass, increase the degree of protection from UV light compared to formulations not containing bioactive glass. Not limited to a particular theory, it is assumed that a high and irregular surface area of fine-grained bioactive glass contributes to the implementation of such protection from UV light. Moreover, reactive glass surface provides NSA layer that serves as additional protection against UV light. In addition, such formulations contribute to the mitigation of sun allergies result from the extraction of soluble calcium.

Bioactive glass begins to absorb UV light at wavelengths below 380 nm, and the passage of UV light with a wavelength of 280 nm ceratomerinae glass thickness of 5 mm is observed 0% transmittance. Thus, the bioactive glass is an excellent material, impervious to the sun's rays in the UVB region (270-320 nm) and moderately good cancellarius material in the region of UFA (320-440 nm) of the solar spectrum.

The effectiveness of bioactive glass to protect from sunlight increases over time after application to human skin. It is assumed that the bioactive glass reacts with human then with the formation of a porous, mineralogical, Nar-enriched deposits on the surface of the glass. It is believed that such a porous surface sediment scatters solar irradiation, thereby improving the shading characteristics of the bioactive glass in time. Thus, the bioactive glass may be regarded as an active ingredient, shielding the sun's rays, the characteristics of which are improved over time, as the sweat oozing from the skin, is able to activate the light scattering, which is associated with the presence of Drug-enriched surface deposits.

A test was conducted of light transmission through the polished sample 5 mm bioactive glass, reacted with Tris-buffer saline with the formation of surface sediments from the Nar. It was found that pre-reacted bioactive glass was less PR is transparent, than unreacted bioactive glass for any length of transmitted light in the range of 280-600 nm. Apparently, the resulting preliminary reaction layer Nar scatters UV and visible light, and bioactive glass more effectively shields UV irradiation after start of the reaction with human sweat on the skin surface.

Typically the products to care if the sun contain as the active ingredient, avobenzone, titanium oxide, zinc oxide, oxybenzone or sulisobenzone.

Traditional formulations for personal care if the sun contain octylmethoxycinnamate, octisalate, homosalate, chloride benzalkonium, water, PVP (PVP)/eicosenoic copolymer, dickerhoff, triethanolamine, cetyl alcohol, retinilpalmitat, oat extract, tocopherol acetate, panthenol, Dimethicone, trimethylsulfoxonium, & bisabolol, disodium EDTA, isostearic sorbitol, butyleneglycol, Phenoxyethanol, carbomer, xanthan resin and diazolidinyl urea.

Care when tanning can also contain one or more of the following substances: PVP (PVP)/hexadecan, isopropylmyristate, 2-ethylhexylacrylate, crosspolymer acrylates/C10-30 alkylacrylate, acrylate/octylacrylamide copolymer, aloe extract, aluminum stearate, avobenzone (Parsol 1789), barium sulfate, benzophenone-3, benzyl alcohol, BUTYLCARBAMATE, C12-15 alkylen the oat, cetearate-20, Cetearyl alcohol, cetylpalmitate, cyclomethicone, DEA-cetilistat, DMDMH the as dimitrieff, elastin, emulsifying wax NF, ethylhexyl P-methoxycinnamate, perakendecilik, odorants, glycerylmonostearate-450, literallayout SE, hydrolyzed collagen, hydroxypropylcellulose, imidazolidinyl urea, iodopropynyl, isohexadecane, isopropyl (palm oil), butter str, methylanthranilate, methylparaben, mineral oil, octadecene/MA copolymer, octocrylene, octylpyrimidine, octyldodecanol, oxybenzone, paraffin, petrolatum, finitely alcohol, phenylbenzimidazole, distearate of polyglyceryl-3, PPG-12/SMDI copolymer, stearyl ether, GPR-15, propylene glycol, propylparaben, PVP (PVP)/hexadecene, SD alcohol 40, tallow oil, sesquioleate sorbitol, sorbitol, stearic acid, starextremely, stearyl alcohol, titanium dioxide, tribehenin, trifluoromethyl, C1-4, and zinc oxide.

The present invention provides new formulations for care in the sun, by which the bioactive glass is introduced into a combination of any of the above ingredients. The following examples 1-3 presents embodiments of formulations for care when the sun containing bioactive glass, including Sol-gel derived bioactive glass.

Example 1

The composition of the sun is protective gel, containing bioactive glass

INGREDIENTS % mass
The gloss on the basis of str 82,5
Octylmethoxycinnamate 7,5
Benzophenone-3 5,0
Bioactive glass from SCHOTT glass (average particle size < 4 μm) 5,0
  100,0

Example 2

The sunscreen composition of the gel containing Sol-gel derived bioactive glass

INGREDIENTS % mass
The gloss on the basis of str 82,5
Octylmethoxycinnamate 7,5
Benzophenone-3 5,0
Sol-gel derived bioactive glass  
glass SCHOTT 5,0
  100,0

Example 3: Composition sunscreen gel

Formula CPD3-32, J,K,N,0,R,S

Basic sunscreen formulation

INGREDIENTS %
The gloss on the basis of str 87,5
Octylmethoxycinnamate 7,5
Benzophenone-3 5,0
  100,0

Tested recipes:

CPD3-32 J = base sunscreen formulation (see above), SPF~15

CPD3-32 = gloss on the basis of str, SPF~0

CPD3-32 N = basic sunscreen recipe + 2%45s, 0.50=1, 6 μm

CPD3-32 O = basic sunscreen recipe + 2%58s, d50=0,77 mcm

CPD3-32 R = basic sunscreen recipe + 4%45s, d50=1.6 ám

CPD3-32 S = basic sunscreen recipe + 4%58s, d50=0,77 mcm

Diapers, baby wipes and wipes for hands, baby powder and body powder, as well as remedies for diaper rash

The present invention covers a new recipe, with which the bioactive glass is introduced into a variety of diapers, baby wipes and wipes for hands, baby powders and powders for body representing such market products, such as products with the trademarks of A & D, Aloe Vesta, Alpharma, Ammens, Aveeno, Baby Magic, Balmax, Borofax, Boudreaux's, Brite-Life, Burt''s Bees, Caldesene, Calmoseptine, Cashmere Bouquet, Cetaphil, Chubbs, Clinipad, Comfort Bath, Cottonelle, Desitin, Diaparen, Diaper Doubler, Diaper Guard, Dr. Smith's, Drypers, Flander's Fougera, Gerber, Gold Bond, Goodnites, Good Sense, G and W, Huggies, Johnson and Johnson, Kid Fresh, Kleenex, Little Bottoms, Little Forest, Luvs, Mexsana, Nature Boy and Girl, Neutrogena, Nice'N Clean, Paladin, Pampers, Phisoderm, Playtex, Pull Ups, Pure'N Gentle, Purell, Shower to Shower, Smiles, Suave, Soddyboye, Tom's of Maine, Tushies, Vaseline, Wash-Up, Weleda, Wet Ones, as well as the products produced by leading manufacturers and producers of generic drugs./p>

Anti-inflammatory, antimicrobial and hygroscopic properties of bioactive glass are particularly useful for food, diapers, baby powders, anti-diaper rash and moisturizing towels, as they help reduce inflammation, eliminate rashes and unpleasant odors. In addition, bioactive glass can reduce the acidity of urine and able to be activated under the influence of water contained in the urine.

Usually products like diapers include synthetic or natural absorbent materials that absorb moisture, synthetic materials, to prevent leaks, as well as odorant and/or antibacterial agents.

The present invention provides a receiving new recipes for diaper due to the introduction of bioactive glass into a combination of any of the above products. In addition, bioactive glass can be used in the so-called diaper for adults.

Usually cosmetics in the form of baby wipes and wipes for hands contain as the active ingredient disodium cocoamphodiacetate such protective agent as silicone oil, mineral oil, fatty acids, fatty alcohols or vegetable oil, and this moisturizer as a gel based on aloe Vera, propylene glycol and PEG-60.

Traditional recipes for children sulfato and wipes for hands contain water, propylene glycol, PEG-75 lanolin, cocoamphodiacetate, Polysorbate 20, methylparaben, 2-bromo-2-nitrophen-1,3-diol, propylparaben, gel based on aloe Vera and fragrances.

Baby wipes and wipes for hands can also include one or more of the following substances: cocamidopropyl PG-Demonologist, crosspolymer on the basis of acrylates/C10-30 alkylacrylate, chloride acetaminophenramadol, acrylate copolymer, alkylpolyglycoside, aminomethylpropanol, chloride benzalkonium, benzoic acid, C12-15 alkylbenzoic, citric acid, diazolidinylurea, Dimethicone, disodium EDTA, centripetal, DMDH the as ethyl alcohol, glycerin, isopropylmyristate, malic acid, nonoxynol 9, IG-20, phosphate, phospholipid CDM, phospholipid EFA, polyaminopropyl, Laureth phosphate of potassium, potassium sorbate, retinilpalmitat, SD alcohol 40, simethicone, sodium benzoate, sodium nonoxynol-9, sorbic acid, tetranitro EDTA, tocopherol acetate, and various vitamin and herbal extracts.

The present invention provides a new recipe for baby wipes and wipes for hands, resulting from the introduction of bioactive glass into a combination of any of the above ingredients.

As a rule, baby powder and powders for body contain talc and/or corn starch, zinc oxide and fragrances.

The usual recipe for kids is such powders and powders for body contain corn starch or talc, sodium bicarbonate, aloe Vera, tricalcium phosphate and fragrances.

Baby powder and powders for the body may also include one or more of the following substances: tricalcium phosphate, bentonite (natural clay), kaolin, polysaccharides purified rice flour, silicon oxide, zinc oxide, hydroxyquinolin, sulfate, 8-hydroxyquinoline solution, ezoterikova acid, GPR-20, air methylglucose, magnesium carbonate, zinc stearate, camphor, chloride benzalkonium, and a variety of fruit, mineral, vitamin, and herbal extracts.

The present invention provides new formulations for baby powders and powders for the body that receive the introduction of bioactive glass in any combination of the above ingredients.

Generally, remedies for diaper rash contain zinc oxide and fish oil, or oil of cod liver oil.

Conventional formulations of anti-diaper rash contain petrolatum, lanolin, oil of cod liver oil, fragrances, mineral oil, microcrystalline wax and paraffin wax.

Cosmetic remedies for diaper rash can also include one or more of the following substances: balm, benzoic acid, water, subnitrate bismuth, borax, silicone, methyl paraben, talc, trihydroxystearin, bisabolol, polyparaben and imidazolidinedione.

The present invention provides new formulations for cf the of funds against diaper rash, who get the introduction of bioactive glass in any combination of the above ingredients.

Antimicrobial, anti-inflammatory and hygroscopic properties of bioactive glass are particularly useful for use in the media against diaper rash to reduce inflammation, eliminate rashes and odor.

Applicators (bra)

Bioactive glass may also be entered in a variety of applicators (bra), including the applicators are manufactured under the trademarks Curity, Healthflow, Gerber, Jonson''s, Evenflo, Omron, as well as the products produced by the leading and reputed manufacturers.

Antimicrobial and anti-inflammatory effects, rendered bioactive glass are particularly useful for applicators (bra) as a means of reducing inflammation, eliminating the rash and odor.

Funds for make-up.

The present invention covers a new recipe, with which the bioactive glass is introduced into the different varieties of products for makeup, including mascara, eyeshadow, pencil eye liner and eyebrows, blush, concealer, face powder, lipstick, lip gloss, cosmetics for lips, contour lip pencil, nail Polish and means for removing nail Polish, such as the products sold under the trade mark is mi Almay, Alpha Hydrox, Aromatherapaes, Bari, Black Radiance, Blistex, Bonnie Bell, Brite-Life, Burt''s Bees, Caboodles, Carmex, Chap-et, Chapstick, Chattenn, Clinipad, Coty, Cover Girl, Curity, Cutex, Dermatone, Garden Botanika, Herpecin-L, Jane, Jason, Kid Care, L'oreal, Liquimat, Loud Music, M Professional, Max Factor, Maybelline, Milani, Natural Ice, Neutrogena, Noxzema, Ocusoft, Oil of Olay, Orly, Peterson's, Purpose, Revlon, Sally Hansen, Savex, Softlips, Stay Free, Tampax, United Colors of Benetton Cosmetics, Ultimates, Vaseline, Viractin, Wet'n'wild, Woltra, Zilactin, as well as the products produced by the leading and cool vendors.

Anti-inflammatory and antimicrobial properties of bioactive glass are particularly useful for make-up products in terms of fighting bacteria and reducing inflammation.

Usually mascara and eyebrow contains talc, wax, preservatives and coloring agents.

Traditional recipes mascara and eyebrow contain water, beeswax, Cyclopentasiloxane, literallayout copolymer BCP-17, Carnauba wax, stearic acid, paraffin, butyleneglycol, EDTA, polyethylene, nylon-12, poly (methyl methacrylate), PVP (PVP) copolymer, PVP (PVP) silicon oxide, triethanolamine, synthetic wax, hydrolyzed corn starch, panthenol, dimethiconol, isotec-20, hydroxyethyl cellulose, diazolidinylurea, methylparaben, simethicone, butylparaben, disodium octylacrylamide/acrylates/butylmethacrylate copolymer, cocoamphodiacetate, tocopherylacetate, triisostearate of isopropylidene, lecithin, triethylamine 2 oleamide-1,3-Oct is decandiol and propylparaben.

Consider carcasses may contain one or more of the following substances: mica, tea-stearate, literallayout, tricontanyl PVP, silk powder, diglycol/cnwm/isophthalate/si copolymer, RTEE, stearate, sorbitol laurate, Polysorbate 20, Arabian gum, acrylate copolymer, denatured alcohol, aminomethylpropanol, ammonium acrylate copolymer, ammonium hydroxide, lanolate ammonium, ascorbyl palmitate, benzyl alcohol, BHA, butilstearat, C9-11 isoparaffin, candelilla wax, Carmine, cetyl alcohol, cetylstearyl, chromium hydroxide green, citric acid, cyclomethicone, ethylparaben, fragrances, glycerol, glycerinated, hydroplex Hhg Whn, hydrolyzed keratin, hydroxyethyl cellulose, imidazolidinethione, iron oxides, kaolin, magnesium silicate-aluminum, ethylpropylamine/Phenoxyethanol, MIPA.-lanolate, MIPA.-oleate, oxynol-10, oleic acid, alerby alcohol, stearate PEG-100, pentaerythritoltetranitrate, Phenoxyethanol, polybutene, polyethylene, polyquaternium 10, polyvinyl alcohol, potassium acadeny-12, phosphate, propylene carbonate, propylene glycol, propyl, quaternium-15, quaternium-18, hectorite, quaternium-22, SD - alcohol 40-In the silicon oxide, silk powder, dehydroacetic sodium, sodium Laureth sulphate, sodium lauryl sulphate, polymethacrylate sodium, sesquioleate sorbitol, talc, titanium dioxide, triclosan, trim telelogistika, trinacria EDTA, Ultramarines and xanthan gum.

The present invention provides new formulations carcass for eyelashes and eyebrows, obtained by the introduction of bioactive glass into a combination of any of the above ingredients.

Usually, eyeshadow contain talc, mica, polyethylene veratile, magnesium stearate and coloring agents.

Traditional recipes eyeshadow contain cyclomethicone, talc, boron nitride, trimethylsulfoxonium, polyethylene, synthetic wax, microcrystalline wax, zinc stearate, kaolin, Dimethicone, retinilpalmitat, tocopherylacetate, aloe extract, silk powder, silica-RTEE, dehydroamino acid, methylparaben, propylparaben, ethylparaben and thiazolidinedione.

Eyeshadow can also contain one or more of the following chemicals: talc, boron nitride, trimethylsulfoxonium, polyethylene, synthetic wax, microcrystalline wax, zinc stearate, kaolin, Dimethicone, retinilpalmitat, tocopherylacetate, aloe extract, silk powder, silica-RTEE, dehydroacetic acid, methylparaben, propylparaben, ethylparaben, diazolidinylurea.

Eyeshadow can also contain one or more of the following ingredients: ascorbyl palmitate, beeswax, hectorite of benzyldimethylamine, BHT, bismuth oxychloride, C12-C15, alkylant is t, calcium silicate, candelilla wax, a triglyceride/Caprylic/capric acid, Carnauba wax, chromium hydroxide green, mixed green chromium oxides and iron, citric acid, karacapilidis, DI tocopherol, gidrirovannoe oil, gidroksilirovanii lanolin, imidazolidinyl urea, isopropyl triisostearate the titanate, lauroyl lysine, lauryl lysine, lecithin, lipophilic glycerol monostearate, magnesium carbonate, manganese violet, methylpolysiloxanes, mica, mineral oil, octyldodecanol, paraffin, parahydroxybenzoate, polymethylmethacrylate, polyvinylidene copolymer, propylene carbonate, quaternium-15, glycerides of saturated fatty acids, dehydroacetic sodium, a mixture of soy phospholipid from soybean lecitina, stearic acid, titanium dioxide, Triowin, tristanian, Ultramarines, zinc oxide, iron oxides, releasesstatements iron, double salt genesisscientific of iron and ammonium, Carmine, diisostearate of polyglyceryl-3, hydrogenated cocoglyceride, ethylene/methacrylate copolymer, nylon-12, pentahydrochloride, acrylate copolymer, isostearate of polyglyceryl 4 laurylamine copolyol, performancemeasurement, butylparaben, Phenoxyethanol, and various coloring agents.

The present invention provides new formulations mascara and bro is her obtained by introducing a bioactive glass into a combination of any of the above ingredients.

Usually, pencils for eye liner and eyebrow pencils contain talc, mica, polyethylene, veratile, magnesium stearate and coloring agents.

Traditional recipes pencils for eye liner and eyebrow pencils contain cyclomethicone, beeswax, archipelagoes, microcrystalline wax, hectorite of quaterni-18, mineral oil, propylene carbonate, methyl paraben, propyl paraben and EIT.

Pencil eye liner and eyebrow pencils can also contain one or more of the following substances: ministerului ether BCP-2 and propionate Teresina, castor oil, vegetable oil, lanolin, aluminum powder, bronze powder, copper powder, zinc oxide, aluminum powder, ammonium hydroxide, ascorbic acid, ascorbyl palmitate, hectorite of benzyldimethylamine, BHA, bismuth oxychloride, butilstearat, butyleneglycol, butylparaben, candelilla wax, a triglyceride Caprylic/capric acid, Carmine, Carnauba cetyl alcohol, Carnauba wax, ceresin, cerotoma acid, cetyl alcohol, citylove complex esters, cetylpalmitate, chromium hydroxide green, chromium oxide green, citric acid, diazolidinyl urea, Dimethicone, double salt telesistema the East of iron and ammonium, glycerides fish oil, glycerin, gidrirovannoe castor oil, hydrogenated Coco-glycerides, gidrirovannoe the cottonseed oil, hydrogenated fish oil, hydrogenated palm oil glycerides, gidrirovannoe vegetable oil, hydroxyethylcellulose, gidroksilirovanii lanolin, lipophilic glycerylmonostearate, iron oxides, isopropyl C12-C15-pareth-9-carboxylate, Japanese wax, lipophilic glycerylmonostearate, manganese violet, melcinova acid, methylpolysiloxanes, mica, mirelly alcohol, oleostearin, ozokerite, paraffin, parahydroxybenzoate, PEG-8, polyethylene, Polysorbate 60, GPR-15, GPR-5 ate-20, PVP (PVP) Laureth-4, quaterni-18 bentonite, glycerides of saturated fatty acids, mica, sorbitol stearate, soybean phospholipid and soybean lecithin, stearic acid, steuergeraet, styrene/acrylate copolymer, talc, glycerides taly fat, titanium dioxide, Tocopheryl acetate, tristearin, Ultramarines, various minerals, vitamins, zinc stearate and various plant and vegetable extracts.

The present invention provides new formulations pencils for eye liner and eyebrows, obtained by the introduction of bioactive glass into a combination of any of the above ingredients.

Usually blush contain talc, preservatives, softener and coloring agents.

Traditional recipes rum is n include Dimethicone, octylpyrimidine, talc, nylon-12, diisooctyl neopentyl glycol, tribehenin, isostearyl begent, boron nitride, acrylate copolymer, retinilpalmitat, methoxypropylamine, chitin extract, hyaluronate sodium, hydrolyzed the glucosaminoglycans, lecithin, candelilla wax, soy amino acids, minasny wax, pentahydrochloride, trioleate sorbitol, water, propylene glycol, silica, Phenoxyethanol, butylparaben titanium, isopropylparaben, isobutylparaben, BHA, lauryl lysine and methyldihydromorphine.

Blush can also include one or more of the following substances: acetylated lanolin alcohol, allantoin, ascorbyl palmitate, barium sulfate, BHT, bismuth oxychloride, butylparaben, C12-C15 of alkylbenzoic, calcium silicate, camphor, carbomer, Carmine, tetracetate, clove oil, karacapilidis, diazolidinylurea, ethylparaben, eucalyptus oil, double salt genesisscientific of iron and ammonium, releasesstatements iron, perfumes, imidazolidinethione, iron oxides, kaolin, manganese violet, menthol, methylparaben, mica, mineral oil, oat flour, octyldodecanol, panthenol, polyethylene, Polyoxymethylene, Polysorbate 20, Polysorbate 80, quaterni-15, dehydroacetic sodium, adaptabilities, tin oxide, titanium dioxide, triethanolamine, trimet celexacelexa, dioctanoyl, Ultramarines, various coloring agents, various plant extracts, zinc stearate, hydrogenated cocoglyceride, activitiesthat, Ultramarines and coloring agents.

The present invention provides new formulations blush resulting from the introduction of bioactive glass into a combination of any of the above ingredients.

Usually the mask and toning tools comprise of isoeicosane, Carnauba wax, polyglyceryl-3-diisostearate, silicon oxide, titanium oxide and coloring agents.

Traditional recipes mask and toning tools include water, butyleneglycol, Dimethicone, isostearoyl alcohol, synthetic wax, cyclomethicone, sesquistearate PEG-20 methylglucose, sodium stearate, tribehenin, polymethylmethacrylate, salicylic acid, hydrolyzed vegetable protein, silica, talc, microcrystalline wax, dimethiconol copolyol, polyglyceryl-6-polyricinoleate, aluminum stearate, boron nitride, dimethiconol, diisostearate, casein, carrageen, tocopherylacetate, retinilpalmitat, aloe extract, ascorbic acid, menthol, calcium chloride, nylon-12, performancecriteria ether, methyl paraben, propyl paraben and Phenoxyethanol.

The mask and toning cosmetics can also switch the th one or more of the following substances: paraffin, pentaerythritoltetranitrate, activitiesthat, cateret-20, seceret-2, DMDMH the as of quaterni-15, dextrin, calcium silicate, zinc stearate, octyldodecyl, tridecylamine, bis-deglycerolized/capret/ isostearate/ stearate, glycerinated, acetylated picoliters, acetylated lanolin, acetylated lanolin alcohol, acrylate copolymer, denatured alcohol, alkylated, allantoin, aluminum hydroxide, octenylsuccinate aluminum starch, aminomethylpropanol, archipelagoes, ascorbyl palmitate, barium sulfate, beeswax, bentonite, benzoic acid, BHA, BHT, bisabolol, Bisacodyl, bismuth oxychloride, butylparaben, octanoate alcohols C12-C15, C12-15 alkylbenzoic, calcium aluminum borosilicate, kandellilsky wax, Caprylic/capric triglyceride, Carnauba wax, castor oil, cellulose gum, Cetearyl alcohol, tetereluctant, tetracetate, cetyl alcohol, acidimetry copolyol, kakailanganin, diazolidinylurea, dicaprylate/dicaprate, dioctyladipate, dipropyleneglycol, disodium EDTA, delineat diisopropyl dimer, telebrasil, ethylene/methacrylate copolymer, ethylene/vinyl acetate copolymer, flavors, glycerin, literallayout, exellent, hydrogenated cocoglyceride, hydrogenated polyisobutene, imidazolidinethione, hydroxy what s iron isolatedstore, isododecane, isooctadecyl, isopropyltoluene, isopropyl, triisostearate of isopropylidene, isostearyl of neopentanoate, isostearamide, kaolin, lanolin, lanolin alcohol, lanolin oil, Laureth-7, lauroyl lysine, lecithin, lipophilic glycerylmonostearate, a silicate of magnesium, aluminum, magnesium carbonate, magnesium sulfate, matichon, sesquistearate methylglucose, methylpolysiloxanes, mica, mineral oil, myristylated, octamethylcyclotetrasiloxane, octylmethoxycinnamate, octylpyrimidine, octisalate, attrstart, octyldodecanol, octyldodecanol, octyldodecanol, mineral wax, panthenol, pectin, stearate PEG-100, stearate PEG-2, PEG-20 sorbitol, beeswax, PEG-32, PEG-6, PEG-8, petrolatum, vinyldimethyl, polyethylene, polyglyceryl-4 isostearate, polyglyceryl-6 ricinoleate, polyisobutene, Polysorbate 60, propylene glycol, PVP (PVP), hectorite of quaterni-18, SD alcohol 40b, silk powder, sodium chloride, dehydroacetic sodium, hyaluronate sodium, lauroylsarcosine sodium, sorbic acid, sesquioleate sorbitol, stearic acid, starextremely, stearyl alcohol, stallsteismer, tert-butylhydroquinone, tetranitro EDTA, titanium dioxide, Tocopheryl linoleate, tricontanyl PVP (PVP), triethanolamine, trihydroxystearin, trimethylsulfoxonium, trinacria ETA, tristearin, ultramarine blue, va/vinylethylene, xanthan gum, and various coloring agents.

The present invention provides new formulations mask and toning cosmetics, which is produced by introduction of bioactive glass into a combination of any of the above ingredients.

Usually, face powder contains talc, preservatives, calcium stearate and coloring agents.

Traditional formulations of powders for the face include talc, mineral oil, zinc stearate, kaolin, octenylsuccinate aluminum starch, acrylate copolymers, silk powder, silica, propylparaben, methylparaben, calcium silicate, imidazolidinethione, dioxides iron and Ultramarines.

Face powder can also contain one or more of the following substances: acetylated lanolin alcohol, ascorbylpalmitate, beeswax, BHT, bismuth oxychloride, camphor, Caprylic/capric triglyceride, Carmine, clove oil, cyclomethicone, dextrin, diazolidinylurea, Dimethicone copolymer of ethylene/acrylic acid, ethylparaben, eucalyptus oil, perfumes, glycerinated, hydrogenated lecithin, isopropyl, lauroyl lysine, lecithin, magnesium stearate, magnesium sulfate, manganese violet, menthol, matichon, methylethylenediamine/Phenoxyethanol, mica, Nai is he-12, oat flour, octylpyrimidine, steamrollered of octyldodecanol, octyldodecanol, panthenol, Phenoxyethanol, fenitrothion, Polysorbate 20, propylene glycol, quaterni-15, hectorite of quaterni-8, retinilpalmitat, dehydroacetic sodium, the sodium salt of hydrogenated taly glutamate, sesquioleate sorbitol, trioleate sorbitol, titanium dioxide, tocopherylacetate, triclosan, tridecylamine, various coloring agents, various plant extracts, water, aloe extract and allantoin.

The present invention provides new formulations face powder obtained by the introduction of bioactive glass into a combination of any of the above ingredients.

Usually lipsticks and lip gloss include castor oil, Caprylic/capric triglycerides, stearic acid, lanolin, polybutene, mineral oil, kaolin, silica, BHT, and coloring agents.

The traditional formulation of lipsticks and lip gloss contain trichilogaster, isotretinoina, C10-20 cholesterol/lanosterol esters, synthetic beeswax, paraffin, cetyl alcohol, candelilla wax, aloe extract, retinilpalmitat, tocopherylacetate, ascorbyl palmitate, hyaluronate sodium, PEG-20 sorbitan beeswax, hectorite of quaterni-18, benzoic acid, BHA, methylparaben, propylparaben, CI is xed titanium, mica, dioxides iron and various coloring agents.

Lipsticks and lip gloss may contain one or more of the following substances: acetylated lanolin, acrylate copolymers, allantoin, ascorbyl palmitate, beeswax, bis-deglycerolized-2, bismuth oxychloride, butylparaben, With 10-30 cholesterol/lanolinovy esters, Carnauba wax, castor oil, tetracetate, acidimetry copolyol, tetrachromat, citric acid, cocoa butter, coconut oil, cyclomethicone, Cyclopentasiloxane, cyclotetrasiloxane, aminobutiramida, dimeric delineat, dimethicon, triisostearate, DI-tocopherol, drometrizole, D-tocopherol, ethylcellulose, odorants, glyceridae, grape seed oil, exellent, hydrogenated polyisobutene, hydrogenated soy glycerides, gidrirovannoe vegetable oil, hydrolyzed collagen, hydrolyzed the glucosaminoglycans, isolatedstore, isododecane, isopropylmyristate, isostearamide, lanolin, magnesium ascorbyl phosphate, menthol, matichon, sesquistearate methylglucose, microcrystalline wax, mineral oil, myristylated, neopentylglycol, activitiesthat, octylmethoxycinnamate, octylpyrimidine, octyldodecanol, alerby alcohol, oxybenzone, ozokerite, padimate, PEG-20 sorbitan beeswax, pentaerythritoltetranitrate is, pentaerythrityl tetraisostearate, vaseline, phytosterols/octyldodecyl lauroylgultamate, polybutene, polyethylene, politin, polyglyceryl-2 diisostearate, polyglyceryl-3 diisostearate, polyglyceryl-4 isostearate, polymethylsilsesquioxane, BCP 51/smdi copolymer, propylgallate, propylene glycol, PVP (PVP)/hexadecanoyl copolymer, sesame oil, shellac wax, silicon dioxide, sodium hyaluronate, sodium lactate, sodium PCA, sodium phosphate, sodium saccharin, sorbic acid, squalane, stearic acid, stearyl Dimethicone, isobutyrate sucrose acetate, tert-butylhydroquinone, tocopherylacetate, trihydroxystearin, triisostearate, triisostearate, trimethylsulfoxonium, urea, various synthetic and natural flavors, various vitamin agents, water, wheat germ oil, Caprylic/capric triglyceride, ceresin, trifluoromethyl, C1-4 alkyldimethyl, archivepoints, fenitrothion and EIT.

The present invention provides new formulations of lipstick and lip gloss, obtained by the introduction of bioactive glass into a combination of any of the above ingredients.

The following code example 4 shows embodiments of formulas of lipstick that includes a bioactive glass.

Example 4

Lipstick with biosteam Compositions CPD3-33 a,b,C

0,1
Ingredients A,% In,% mass C,wt%
  mass    
Part a      
Red 7 CA Lac 3,0 3,0 3,0
Red 7 VA lacquer 1,0 1,0 1,0
Red 33 AI lacquer 1,0 1,0 1,0
Castor oil 15,0 15,0 15,0
Part b      
Castor oil 30,6 30,6 30,6
Carnauba wax 2,0 2,0 2,0
Candelilla wax 7,0 7,0 7,0
Ozokerite wax 2,0 2,0 2,0
Microcrystalline wax 3,0 3,0 3,0
Oil str 25,0 25,0 25,0
Vitamin E 15,0 15,0 15,0
Methylparaben 0,1 0,1
Propylparaben 0.2 0,2 0,2
The SCHOTT glass 45s5 (average particle size <4 μm) 0,1 0,1 0,1
Part      
Talc USP 10,0 - -
Biostable 45s@ 1,6μ - 10,0 -
Biostable 58s@ 0,77μ - - 10,0
  100,0 100,0 100,0

Observations:

1) the composition of the talc hardens not as good and fast as the composition containing any glass

2) the composition of the glass 58s hardens slightly faster and produces a smoother product than on the basis of glass 45s.

3) the composition of the talc for 1 hour shows more bleed (wypadanie).

Usually means care for the lips contain moisturizers, healing agents and protective tools, such as jelly vaseline.

Traditional recipes care for lips contains white petrolatum, ethylhexyl P-methoxycinnamate, Carnauba wax, gidroksilirovanii milk glycerides, nylon-12, paraffin, tocopherylacetate, bisabolol, retinilpalmitat, panthenol, lecithin, stearic KIS the PTA, soy Sterol, zinc sulfate, sodium saccharin, various natural and artificial flavors and various plant extracts.

Means for lip care can also contain one or more of the following substances: 2-ethylhexylacrylate, 2-octyldodecanol, allantoin, aloe extract, alum Chine, archivepoints, beeswax, benzoic acid, benzophenone-3, BHT, Bisacodyl, borage seed oil, camphor, Carnauba wax, castor oil, cetyl alcohol, citylove esters, cocoa butter, corn oil, Dimethicone, dipentaerythrityl/hexacaprate/hexacaprylate, odorants, gidrirovannoe castor oil, isopropylmalate, oil from the fruit of the lacquer tree, lanolin, menthol, methylparaben, microcrystalline wax, mineral oil, mixed wax, octadecene/mA copolymer, octylmethoxycinnamate, octylpyrimidine, oxybenzone, ozokerite, padimate, paraffin, petrolatum, phenol, polybutene, polyphenylmethylsiloxane 556, Politiken, propylparaben, purified water, saccharin, salicylic acid, SD alcohol 36, stearyl alcohol, sunflower oil, talc, tredecillion, tridecylamine, triisostearate esters, various coloring agents, paraffin wax and white wax.

The present invention provides new formulations of products for lips that get the introduction of bioactive glass in the hand and from any of the above ingredients.

Usually contour pencils for lips contains a wax material, preservative, mineral oil, stearic acid, and coloring agents.

Traditional formulations of these pencils contain castor oil, isopropyl, lanolin, beeswax, candellila wax, oil, meadow grass, perfumes, sesame oil, polybutene, mineral wax, dioctadecyl foretelleth, Carnauba wax, paraffin, hydrogenated soy glycerides, propylene glycol, stearic acid, sodium saccharin, propylparaben, propylgallate and citric acid.

Contour pencils for lips can also contain one or more of the following substances: aloe extract, BHA, bismuth oxychloride, bronze powder, butylparaben, Carmine, castor oil, ceresin, copper powder, cyclomethicone, diisostearate dimer of delineat, hydrated oxide of silicon, gidrirovannoe castor oil, gidrirovannoe oil cotton seed, iron oxides, manganese violet, methylparaben, mica, PEG-6, beeswax, quaterni-18 bentonite, retinilpalmitat, sodium saccharin, synthetic wax, titanium dioxide, tocopherylacetate, various coloring agents, various natural and artificial flavors, zinc oxide, ascorbyl palmitate, glycerides of saturated fatty acids, triglycerides of Caprylic/capric acids, glyceride allmetal, parahydroxybenzoate, soybean phospholipid, soybean lecithin and lipophilic glycerylmonostearate.

The present invention provides for new recipes contour lip pencil by introducing a bioactive glass into a combination of any of the above ingredients.

Typically, the tools for nail polishing contain nitrocellulose lacquer dissolved in solvents such as acetone or ethyl alcohol and coloring agents.

Traditional recipes polishes nails contain ethyl acetate, butyl acetate, isopropyl alcohol, nitrocellulose, glyceryltrinitrate, acetyltributyl, stearalkonium bentonite, stearalkonium hectorite, glyceryltrinitrate, camphor, SD alcohol 40, citric acid, maleic acid, phosphoric acid, 2,4-di-tert-butylphenyl-3,5-di-tert-butyl-4 hydroxybenzo and tin oxide.

Products for nail polishing can also contain one or more of the following substances: acrylate copolymer, an extract from seaweed, aluminum, amylacetate, benzophenone-1, Biotin, bismuth oxychloride, chromium hydroxide green, green oxide of chromium, datetoday alcohol, dibutyl phthalate, dimethiconol copolyol, dipropyleneglycol dibenzoate, ecitoninae, etocrylene, ferrocyanide iron-aluminum, ferrocyanide iron, fiberglass, odorants, pikosky copolymer, guanine, guide atroveny silicon oxide, the oxides of iron, isobutyl acetate, manganese violet, methyl acetate, mica, N-butyl alcohol, oxidized polyethylene, panthenol, phthalic anhydride, a copolymer of phthalic anhydride/glycerin/glycidaldehyde, a copolymer of phthalic anhydride/trimellitic anhydride/glycol, polyester resin, polyethylene terephthalate, propyl, retinilpalmitat, silicon oxide, silver, styrene/acrylate copolymer, isobutyrate sucrose acetate, styrene/acrylate/ Acrylonitrile copolymer, tetrabutyltin hydroxybenzoate, titanium dioxide, tocopherylacetate, tosylamide/epoxy resin, tosylamide/ formaldehyde resin, timentin, trimellitic dioxide, Ultramarines, various coloring agents, hectorite stearalkonium, dimethiconol copolyol, acrylate copolymer, dipropylenetriamine, tribesmen, Biotin, panthenol, retinilpalmitat, tocopherylacetate, powdered aluminum, bismuth oxychloride, polyester resin, isobutyrate acetate sucrose, datetoday alcohol, benzophenone-1, guanine, tosylamide/formaldehyde resin, dibutyl phthalate, tetraethylorthosilicate, titanium dioxide, dioxide iron, mica, mixed ferrocyanide of iron and ammonium, pattent calcium, heptane, etocrylene, acetyltributyl, hydrolyzed keratin and various coloring agents.

The present invention is provided for the new recipe polishes, nail, get the introduction of bioactive glass into a combination of any of the above ingredients.

Bioactive glass and Sol-gel derived bioactive glass react with aqueous liquids to form a solution, enriched with such inorganic elements such as calcium, phosphorus, sodium and silicon. These inorganic elements are able to settle on the nail with the formation of the mineral layer (e.g., hydroxyapatite). It is assumed that this layer gives the nails a big strength.

The following examples 5-8 presents embodiments of formulations polishes, nail containing bioactive glass, including Sol-gel derived bioactive glass.

Example 5

The composition of the anhydrous gel I for hardening nails

Ingredients % mass
Composition for brightening on the basis of str 80,0
Bioactive glass SCHOTT (srirasmi particles < 4 μm) 20,0
  100,0

Example 6

The composition of the anhydrous gel II for hardening nails

Ingredients % mass
Composition for brightening on the basis of str 90,0
Bioactive glass SCHOTT (srirasmi particles < 4 μm) 10,0
  100,0

Example 7

The composition of gel Polish (anhydrous material containing bioactive glass)

Ingredients % mass
Glycerin 90,50
Pemulen®TR-2 0,45
Bioactive glass SCHOTT (srirasmi particles < 4 μm) 9,05
  100,0

Example 8

Composition for the care of nails and skin (anhydrous, containing Sol-gel derived glass)

Ingredients % mass
Composition for brightening on the basis of str 91,5
Brown iron oxide 0,5
Titanium dioxide 0,5
Talc USP 2,5
Sol-gel derived bioactive glass SCHOTT 5,0
  100,0

Typically, the means for removal of nail Polish from the nails include acetone, or ethyl acetate.

Traditional recipes of removing the nail Polish contain ethyl acetate, alcohol, water, propylene carbonate, dimethylpent is at, dimethylsuccinic, dimethyladipate, gelatin, glycerin, diglycerin, odorants, isopropanol, propyl, benzophenone-1, castor oil and various coloring agents.

Means for removal of nail Polish can also contain one of the following substances: acetone, citric acid, benzoate of dentonia, PEG-75 lanolin oil, mineral oil, panthenol and tocopherylacetate.

Bioactive glass may be a combination of any of the above ingredients.

Swabs, cosmetic pads and strips

The present invention covers a new recipe, with which the bioactive glass is introduced into a variety of swabs, cosmetic pads and gaskets, such as market products with trade names Always, Carefree, Kotex, o.b., Playtex, Tampax, and products produced by leading manufacturers of cosmetics.

Typically, the pad means include cotton and/or cellulose wrap and cotton cord.

Pad products may also include one or more of the following substances: polyethylene/polyester sealer, Polysorbate-20, odorants, and a plastic or cardboard applicator.

Usually cosmetic pads and strips contain cellulose, plastic and adhesive tapes. These funds may also contain fragrances.

The present invention covers the et new recipes tampons, cosmetic pads and strips, obtained by the introduction of bioactive glass into a combination of any of the above ingredients.

Antimicrobial and hygroscopic effects of bioactive glass are particularly useful for use in tampons, cosmetic pads and strips, as they help to destroy bacteria and eliminate the odor.

Preventive drugs and medicines for acne

The present invention covers a new recipe, with which the bioactive glass is introduced into various sorts of preventive and drugs against acne, such as market products, manufactured under the trade names Acne Aid, Aconmel, Aveeno, Biore, Burt''s Bees, Clen and Clear, Clear Logix, Clerasil, Desert Essence, Exact, Fostex, Garden Botanika, Hyland's Homeopathic, lonax, Jason, Johnson& Johnson, Kiss My Face, Liguimat, Neutrogena, Noxzema, Orange Daily, Oxy, Pamoxyl, Pernox, Pond s, Rezamid, Sal Ac, Salicylic Acid, Sastid, Sebasorb, Stiefel, Strindex, Suave, Sulforcin, Sulfur Soap, Sulpho-Lac, T-Zone, Zirh, as well as the products produced by leading manufacturers.

Typically, preventive medicines and struggle with acne contain as the active drug benzoyl peroxide or salicylic acid.

Traditional recipes preventive drugs and struggle with acne contain active ingredients, consisting of a combination of resorcinol, sulfur and alcohol or feather the sid benzoyl.

Preventive drugs and means of dealing with acne can also include one or more of the following inactive ingredients: alcohol, attapulgite, bentonite, butylparaben, carbomer, citric acid, sulfosuccinate dictinary, disodium EDTA, disodium edetate, EDTA, flavors, glycerin, hydroxyethyl cellulose, hypromellose, iron oxides, isopropylmyristate, kaolin, lauramide DEA, methylparaben, parachlorometaxylenol, laurate PEG-8, potassium hydroxide, propylene glycol, propylparaben, salicylic acid, simethicone, sodium bisulfite, borohydride sodium, sodium chloride, Cocoate sodium, sodium hydroxide, sodium of polynaphthalene, tallowate sodium, talc, titanium dioxide, trinacria hedta, various plant and mineral extracts, water, xanthan resin, zinc oxide, aluminum hydroxide, glycerol stearate SE, and PEG-12.

The present invention provides a new formulation of preventive and drugs against acne, obtained by the introduction of bioactive glass into a combination of any of the above ingredients.

Antimicrobial and anti-inflammatory properties of bioactive glass are particularly useful for prophylactic and drugs against acne. The bioactive glass can be used in protivopravnych creams topical application with C is poured reduce inflammation, at the same time it contributes to the destruction of bacteria and microorganisms that cause acne.

Tools for face cleansing, toning, exfoliation and removing make-up

The present invention covers a new recipe, with which the bioactive glass is introduced into a variety of products for face cleansing, toning, exfoliation and removal tools makeup, such as commercial products under the brands Aapri, Albolen, Almay, Alpha Hydrox, Ambi, Aqua Glycolic, Aquanil Lotion, Artra, Aveeno, Basis, Biore, Bodycology, Bonnie Bell, Brite-Life, Burts''s Bees, Camocare, Cetaphil, Clean&Clear, Clairol, Clearasil, Clerly Natural, Cover Girl, Curad, Diskinson's, DMI, Earth Science, Freeman, Garden Botanica, lonax, Jason, Jergens, Johnson& Johnson, Keri, Kiss My Face, La Bella, L'oreal, Maybelline, Moisturel, Neutrogena, Nieva, Noxzema, Oil of Olay, Oxy, Phisoderm, Plenitude, Pond s, Propa pH Purpuse, they not only, Revlon, RoC, Sea Breeze, Seban, St. Ives, Swiss Formula, Stiefel, Stridex, Suave, T-Zone, Ten-O-Six, Vegee Tonic, as well as the products produced by leading manufacturers.

Usually cleaning the face, toning drugs or exfoliating tool or tools makeup remover contain camphor, water, menthol, stearic acid, calcium hydroxide, ammonium hydroxide and this exfoliating agent as alpha or beta hydroxy acid, retinoic acid, azelaic acid or adapelene.

Traditional recipes for the cleaning the face, toning drugs, exfoliants and means for removing make-up contain in the u, glycerin, sodium Laureth sulfate, cocamidopropyl betaine, tocopherylacetate, panthenol, mutilated, cariety/steareth-20, methacrylate copolymer, xanthan resin, microcrystalline wax, sodium silicate-magnesium, sodium hydroxide, odorants, DMDMH the as iodopropynyl of BUTYLCARBAMATE, various vitamins, mineral, fruit and vegetable extracts and various coloring agents.

Means for cleaning the face, toning drugs or exfoliating tool or tools makeup remover can also contain one or more of the following substances: 1-hexadecanol, adpropinquabant, acrylate of crosspolymer, acrylate/C10-3 - alkyl, allantoin, ammonium hydroxide, beeswax, benzophenone-3, benzyl alcohol, beta carotene, BHT, boric acid, butyleneglycol, butylparaben, camphor, Caprylic/capric triglyceride, carbomer, ceresin, claret-20, Cetearyl alcohol, clearlistener, cetyl alcohol, satellitesatellite, tetrachromat, chlorhexidin digluconate, hydroxide green chromium, citric acid, cocamide MEA, cocamidopropyl the phosphatidyl rd-dimoni chloride, oxide cocamidopropylbetaine, colloidal oatmeal, corn germ oil, DEA-cetilistat, diazolidinylurea, dicaprylate/dicaprate, Dimethicone, disodium EDTA, disodium Laureth sulfosuccinate, disodium lauroamphodiacetate, D. the sodium PEG-2 sulfosuccinate, disodium rezinometallicheskie, disodium edetate, EDTA, etokxidiglicol, ethylparaben, gelatin, literallayout, glyceryltrinitrate, literallayout, glycol DS, hexyleneglycol, chloride hydroxyethyl hydroxyethylammonium, chloride, hydroxypropyl guar of hydroxypropyltrimonium, hydroxypropylcellulose, imidazolidinethione, iron oxides, societally alcohol, isopropylmyristate, isopropyl, lactic acid, lanolin oil, Laureth-4, Laureth-9, lauric acid, laurifolia, lowerpriceusa, mixed silicate of magnesium-aluminum, menthol, methylglycol 20, Methylchloroisothiazolinone, metildibromoglutaronitril, the combination, methylparaben, mineral oil, myristic acid, activitiesthat, olive oil, palmitic acid, paraffin, PEG-10 gidrirovannoe castor oil, PEG-10 soy Sterol, stearate PEG-100, PEG-120 glucose dioleate, PEG-120 methylglucose dioleate, distearate PEG-150, stearate PEG-2, PEG-20, glyceryl tallowate PEG-200, distearate PEG-3, literallayout PEG-7, PEG-8; sorbitol laurate PEG-80, tridecylamine ether PEG-9, pendantry Panetta, vaseline, PG-acetate phosphate, Phenoxyethanol, phenethyl alcohol, poloxamer 184, polydecene, Pololikashvili, composition polyoxyethylene 15 calamintha/oleate, polyquaternium-10, polyquaternium-24, polyquaternium-7 capryloyl salicyl the Wai acid, Polysorbate 20, Polysorbate 60, Polysorbate 80, potassium hydroxide, monistat potassium, potassium palmitate, potassium sorbate, potassium stearate, GPR-10 butanediol, methylglucose ether BCP-10, BCPs-12 may be-16, stearyl ether, GPR-15, propylene glycol, propylparaben, quaterni-15, safflower oil, salicylic acid, sesame oil, simethicone, sodium borate, ethoxycarbonyl C12-15 sodium alkoxide, sodium chloride, Cocoate sodium, Cocoyl monosodium glutamate, cocoylisethionate sodium, dodecylbenzenesulfonate sodium, isetionate sodium, isostearyl lactylate sodium, sodium lactate, lauroamphoacetate sodium, lauroyl of sarcosinate sodium, sodium lauryl sulfate, laurylsulphate sodium, myristoylation sodium, palmkernel sodium, sodium PCA, sodium stearate, sodium sulfate, tallowate sodium, cocoylisethionate sodium, holdfast stearamidopropyl rd-demonia, steareth 2 steareth-21, stearic acid, stearyl alcohol, sucrose laurate, talc, tea stearate, tetranitro EDTA, tetranitro Atisreal, titanium dioxide, triclocarban, pendantry pentetate, triclosan, triethanolamine, trinacria hedta, tromethamine, sodium tamilselvam, oleyl betaine, Laureth-3, savemarriage wax cocoamphocarboxyglycinate, lauramide DEA, lauramide MEA, linoleamide DEA, polyethylene, chloride laurylether-10 dihydroxyprogesterone, lauroamphodiacetate sodium, dellplus the Zid.

The present invention provides new formulations for cleaning the face, toning and exfoliating preparations, as well as means for removing make-up, which is produced by introduction of bioactive glass into a combination of any of the above ingredients.

Anti-inflammatory and antimicrobial effects of bioactive glass are particularly useful for use in the media face cleansing, tonic preparations and exfoliating preparations, and means for removing make-up with the purpose of killing bacteria and suppression of inflammatory processes. In addition, the abrasive properties of bioactive glass make it useful for use in exfoliating products.

Lasonya means for wetting the face, wrinkles, skin care around the eyes, hands and body

The present invention covers a new recipe, with which the bioactive glass is introduced into a variety of products for moisturizing facial, wrinkle assets, aging, care products for the skin around the eyes, hands and body, such as the products sold under the trade names Acid Mantle, A-Derma, Abra, Alba Botanica, Albolen, Almay, Ala Derm, Allercreme, Aloe Vera 80, Alpha Hydrox, Alpha Keri, AmLactin, Aqua Care, Aqua Glycolic, Aqua Lactin, Aquanil, Asorbase, ArthiCare, Atrac-Tran, Aveeno, Avon, Baby Magic, Baker Cummins, Balm Barr, Basis, Beauty Without Crvetty, Beta Care, Biore, Bodycology, Brite-Life, Burt''s Bees, Calgon, CamocareGold, Ca-Rezz, Carmol, Carrington, CBI, Cetaphil, Chamberlain, Clairol, Clan&Clear, Complex 15, Coral Springs, Corn Huskers, Curel, Cutar, Cutemol, Dermal Therapy, Darmacerin, Dermaton, Dermovan, DiaDermal, DiabetDerm, Dixie Health, DML, Doak, DPM, Earthly Elements, Earth Science, Earth Therapeutics, Eita, Epilyt, the ashes of esoterica, Estar, Eucerin, Evian, Exorex, Face Lift, Formula 405, Fougera, Freeman, Fruit of the Earth, Galderma, Garden Botanica, Gold Bond, Golden Sun, Good Sense, Healthflow, Hydrox-C, Jamieson&Co., J.C. Brillantine, Jason, Jean Nate, Jergens, Jockey Club, KC&Company, Keri, Kerodex 51, Kiss My Face, La Bella, Lac-Hydrin Five, LactiCare, Lady Esther, Lander, Lanolar, Lantiseptic, Little Forest, Lubrex, Lubriderm, MG-217, Moisturel, Nate'Naturals, Naturade, Naturalife. Nature's Apothecary, Nature, Family, Nature's Gate, Neutrogena, Nivea, Noxzema, Nutraderm, Nutra-E, Nutraplu, Oilatum Ad, Oil of Olay, Optimum Series, Orange Daily, Pacquin, Palmer s, Pen-Kera, Perfect Solutions, Petal Frash, Plenitude, Pond s, Porcelana, - Prax, Pretty Feet& Hands, Proteque, Purpose, Queen Helene, Revlon, Rex Erne, RoC, Rose Milk, Sarah Michaels, Sarna, Sea Breeze, SFC, Seba Nil, Shepard' s, Shikai, Simply Be Well, Soft Sense, State of Mind, St. Ives Swiss Formula, Stik, Stretch Mark, Suave, Sudden Change, Sundance, Soddyboye, The Healing Garden, Theraplex, Triple Lanolin, University Medical, U-Lactin, Ultra Mide 25, Vanicream, Vaseline, Vas Pet, Vital Care, Vitec, Wibi, Wild Yam Complex, Woltra, Xpressions, Yardley''s of London, Zim''s Crack Creme, as well as the products produced by leading manufacturers.

Bioactive glass is particularly advantageous to use in these products, because it has anti-inflammatory and antimicrobial properties. Mild abrasive action and the creation of high pH in some formulations affect the skin exfoliating action and helps to remove wrinkles. In addition, these formulations containing bioactive glass can be used DL is the concealment of the shadows from the wrinkles.

Formulations for application to the skin containing bioactive glass also contribute to the creation of protective NSA layer on the corneous layer of the skin. In addition, anti-inflammatory bioactive glass reduces redness and skin irritation, and antibacterial action disinfects it.

Usually lasonya means for wetting the face, wrinkles, skin care around the eyes, hands and body contain a softening agent, a preservative and collagen.

Traditional recipes lasonic funds to moisturize the face, wrinkles, skin care around the eyes, hands and body contain water, glycerin, stearic acid, aloe gel, glycol stearate, soy Sterol, lecithin, Dimethicone, literallayout, cetyl alcohol, mixed silicate of magnesium-aluminum, odorants, carbomer, stearamide AMR, methylparaben, DMDMH the as iodopropynyl, BUTYLCARBAMATE, disodium EDTA, butyleneglycol, titanium dioxide, mineral, fruit, vegetables and vitamin extracts, as well as coloring agents.

Lasonya means for wetting the face, wrinkles, skin care around the eyes, hands and body can also contain one or more of the following substances: 1-hexadecanol, acemannan hydrogel, acetylated lanolin alcohol, acrylate copolymer, acrylate/C10-30 alkylacrylate crosspolymer, trilat/urethane copolymer, allantoin octyldodecyl pub, alcohol, allantoinate EDTA, alphalipoic acid, octenylsuccinate aluminum starch, ammonium glycolate, ammonium hydroxide, ammonium lactate, oil apricot kernels, the polypeptide of ascorbic acid (vitamin C), ascorbyl palmitate, avobenzone, beeswax, benzophenone-4, benzyl alcohol, BHT, bisabolol, literallayout, boric acid, butyrolactone, C10-30 cholesterol/lanolinovy esters, C12-15 alkylbenzoic, C13-14 isoparaffin, calcium chloride, calcium hydroxide, calcium sulfate, camphor, Caprylic acid, castor oil, ceramide 3, ceresin, ceteareth 20, Cetearyl alcohol, tetereluctant, ceteth-24, chloride ceremony, tetracetate, acidisation, citylove esters, tetrachromat, cetylpalmitate, cetirizine, chloride, chlorphenesin, cholecalciferol, cholesterylester, Cholet-24, citric acid, cocolapalm capret, cocoa butter, Comblain, Collina oat flour, copolymer, cyclomethicone, Cyclopentasiloxane, DEA-cetilistat, DEA-IG-3 phosphate, dermacare (bioactive multi complex varieties of wild yams), desalinisation, dicaprylate/dicaprate, dicaprylyl ether, dicaprylyl maleate, diisopropyl sebacate, dioctanoyl, dioctylamine, dipropyleneglycol, chloride distearyldimonium, distearyldimonium, emulsifiers, etokxidiglicol, telebrasil, this is hexyl P-methoxycinnamate, glycerin, eucalyptol, eucalyptus oil, fumaric acid, gelatin, glucose, glyceraldehyde, glycolic acid, glycoproteins, glisin, GMS/PEG-100 stearate, guar gum, exellent, Galanova acid, gidrirovannoe castor oil, hydrogenated lanolin, hydrogenated polyisobutene, hydrolyzed animal protein, hydroxyethylcellulose, imidazolidinethione, isolatedstore, isotetinoiin, isohexadecane, isopropyltoluene, isopropylmyristate, isopropyl, ezoterikova acid, isostearoyl alcohol, isostearate, isostearamide, kaolin (natural clay), lactic acid, lanolin, thiazolidinedione, Laureth-23, Laureth-4, Laureth-7, lauroyl lysine, linoleamide rd-dimoni chloride phosphate, Flaxseed oil, magnesium ascorbyl phosphate, magnesium sulfate, malic acid, menthol, methylanthracene, Menthyl lactate, methoxypropionate, methyl gluceth-20, methylcellulose, Methylchloroisothiazolinone, metalization, the combination, mineral oil, mink oil, monoglycerides, myristylated, myristoleate, neopentylglycol dicaprylate/dicaprate, nylon-12, activitiesthat, octylmethoxycinnamate, PEG-8 beeswax, phenylbenzimidazole, octylmethoxycinnamate, octylpyrimidine, octisalate, octyldodecanol, octyldodecanol, OK who allodeterminant, leiserson, oxybenzone, palm oil, palmitic acid, stearate PEG-20, PEG-10 soy Sterol, stearate PEG-100, kokumin PEG-15, dilaurate PEG-4 stearate PEG-40, literallayout PEG-5, stearate PEG-50, distearate PEG-8 stearate PEG-8, vaseline, PG dioctanoyl, phenol, Phenoxyethanol, phenylcarbinol, vinyldimethyl, phospholipids, polyacrylamide, distearate polyglyceryl-3 methylglucose, polyglyceryl-4 isostearate, polyglycerylmethacrylate, polyoxyl 40 stearate, Polysorbate 20, Polysorbate 40, Polysorbate 60, potassium hydroxide, potassium sorbate, potassium stearate, progesterone USP, propylene glycol and PVM/MA decadiene crosspolymer, PVP (PVP)/eicosenoic copolymer, PVP (PVP)/hexadecanoyl copolymer, pyridoxine HCL (vitamin B6), quaterni-15, resorcinol, retinilpalmitat, saharadesert, salicylic acid, SD alcohol 40-b, Shea butter, silk amino acid, sodium benzoate, sodium borate, sodium alginate-calcium, carbomer, sodium, sodium chloride, sodium DNA, hyaluronate sodium, isostearoyl lactylate sodium, sodium lauryl sulfate, sodium PCA, Privat sodium, sodium stearate, sorbic acid, sorbitan laurate, sorbitan stearate, sorbitol, soybean oil, special vaseline fraction, squalane, chloride steadily, stearamide DEA, phosphate chloride stearamidopropyl PG-demonia, steareth 2 steareth-21, starextremely, stearyl alcohol, tea, tea-acrylate/C1-30 alkylacrylate crosspolymer, tea-carbomer 941, tea-stearate, tetranitro EDTA, TRANS-vector distribution system (liposomally complex), tricart, tricotrin, tredecillion, tridecylamine, triethanolamine, triisostearate, Triowin, trinacria EDTA, trolamine, urea, wool wax alcohol, collagen, elastin, propyl paraben, PEG-40, clearesult sodium stearyl alcohol, quaterni-22, sodium hydroxide and silicon dioxide.

The present invention provides a new formulation of moisturizers, medications, preventing the appearance of wrinkles, as well as care for the skin around the eyes and lotions for hands and body that receive the introduction of bioactive glass into a combination of any of the above ingredients.

The following examples 9 and 10 shows the embodiment of lotions for skin care/recipes tonal creams and cream foundations makeup containing bioactive glass, including Sol-gel derived bioactive glass.

Example 9

The composition of the basics of skin lotion/makeup containing EOL-gel derived bioactive glass

INGREDIENTS % mass
Mineral oil (70 ssu) 20,0
Polawax® 5,0
Glycerin 2,0
Diiodotyrosine the water 65,4
Jaguar C-14S 0,5
Feeback 1,0
Odorant (leading drug Botanicals AFF#ACR2492019E) 0,1
Powder citric acid monohydrate 2,0
Sol-gel derived glass Shota 4,0
  100,0

Example 10

Cream-based makeup, containing biostable Recipe CPD3-34 a,b,C

INGREDIENTS And, wt% In,%wt C, wt%
Part a      
Crodafos CES 3,0 3,0 3,0
Volpo 10 0,8 0,8 0,8
Volpo 3 0,6 0,6 0,6
Oil str 10,0 10,0 10,0
Cyclomethicone D5 5,0 5,0 5,0
Part b      
Deionized water 59,9 59,9 59,9
NaOH 0,1 0,1 0,1
Volpo 10 0,1 0,1 0,1
TiO2 7,0 7,0 7,0
Yellow iron oxide 0,8 0,8 0,8
Red iron oxide 0,3 0,3 0,3
A mixture of yellow and brown iron oxides, 50/50 0,1 0,1 0,1
Part      
Propylene glycol 3,0 3,0 3,0
Jaguar 13S 0,3 0,3 0,3
Part D      
Talc USP 8,0 - -
Biostable 45s@ 1,6 ám - 8,0 -
Biostable 58s@ 0,77 mcm - - 8,0
Part E      
Germaben II 1,0 1,0 1,0
  100,0 100,0 100,0

Results observations: Recipes 34B and 34 To provide a smoother application than the recipe 34A(based on talc), and both of these formulations are less oily than the recipe 34A. Recipe 34C less oily than the recipe 34B.

Tools of foot care

The present invention covers a new recipe, with which the bioactive glass is put into different varieties of funds on foot care, including drugs to treat fungal infections of the feet and eliminating odor and Mesopotamia products, such as market products, manufactured under the trade names of Absorbine Jr., Aftate, Aloe Vesta, Alpha Hydrox, BFI, Baza, Blis-toSol, Brite-Life, Carrington, Cruex, Desenex, Desert Essence, Dr. School's, Earth Terapeutics, Fougera, Freeman, Fungi Care, Fungiclear, Funginail, Fungi Nail, Fungus Stop, Gold Bond, Helth at home, Johnson's, La Cross, Lamisil, Lotrimin, Mavis, Micatin, Miconazole, Neutrogena, NP-27, Odor-Eaters, Orly, Outgrow, Parex, Pinaud, Podiacin, Pretty Feet& Hands, Quinsana, St. Ives Swiss Formula, Soddyboye, Tetterine, Tinactin, Ting, TingAF, Trim, Triple Care, Vaseline, Zeasorb, as well as the products produced by leading manufacturers.

Recipe for foot care, containing bioactive glass are antimicrobial drugs that have a calming effect. The antimicrobial effect of bioactive glass comprising an antifungal effect, makes it particularly suitable for use in products for foot care. In addition, the hygroscopic properties of bioactive glass help remove moisture from the feet. Bioactive glass may also be used DL is create a pumice stone for feet or be entered in such products. For example, the powders may be subjected to sintering to obtain a porous solid material intended for use as a pumice stone for feet.

Usually means foot care contain as the active ingredient allylamine, azole, griseofulvin, oxiconazole or tolnaftate.

Traditional recipes care for your feet contain active ingredients, consisting of a combination of tolnaftate, undecylenate zinc, miconazole, nitrate, corn starch, zinc oxide, kaolin and potash benzene.

In addition, the means to care for your feet can contain one or more of the following active ingredients: acetone, acrylate copolymer, aldioxa, beginanimation, calendula, carbohydrates.elavil copolymer, ceteareth-6, chloroxylenol, diazolidinylurea, disodium edetate, odorants, imidurea, iodine, isobutane, isopropylmyristate, menthol, microporous cellulose, monobasic sodium phosphate, stearamide diethylamin, myristoleate, Polysorbate 60, Polysorbate 80, potassium iodide, quaternium, SD alcohol 40, sodium bicarbonate, hectorite of stearalkonium, stearamide diethylamin, stearic acid, stearyl alcohol, talc, thymol triglyceridesanother, oil, polani, xanthan gum, water, salicylic acid, methyl salicylate, bentonite, camphor, chloride benzethonium, who terbinafin hydrochloride, benzyl alcohol, cetyl alcohol, cetylpalmitate, sodium hydroxide, sorbitol monostearate, starch, magnesium stearate and various herbal, herbal and mineral extracts.

The present invention provides new formulations care for your feet due to the introduction of bioactive glass into a combination of any of the above ingredients.

Anti skin itching

The present invention covers a new recipe, with which the bioactive glass is introduced into a variety of drugs, antipruritic actions, such as market products manufactured under the trademarks of A&D Ointment, After Bite, Americaine, Aquaphor, Arctic Spray, Aveeno, Baciguent, Bactine, Benadril, Betadine, Blue Star, Boil Ease, Caladryl, Caldecort, Campho-Phenique, Chiggerex, Cortaid, Cortizone, Dermarest, Dennoplast, Exorex, Foille, Gold Bond, Good Sense, Humco, Itch-X, Ivarest, Ivy Block, Ivy-Dry, KeriCort-10, Lanabiotic, Lanacane, Lanacort, Lotrimin, Medi-Quik, Micatin, Mycitracin, Neosporin, Nupercainal, Polysporin, Rhuli, Sarnol-HC, Solarcaine, Sting Kill, Tecnu, Tegrin, Tinactin, Unguentine, as well as the products produced by leading manufacturers.

Usually anti-itch contain as the active ingredient benzocaine, novacain or bacitracin.

Traditional anti-itch contain active ingredients consisting of a combination of camphor, benzocaine, pramoxine of hdrochloride, zinc acetate or hydrocortisone.

Anti-itching can also contain one or more of the trace of the participating inactive ingredients: 1-hexadecanol, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-meth, acetic acid, adhesives, alcohol, aloe extract, aluminum sulphate, ammonia, chloride benzalkonium, benzyl alcohol, bisabolol, butyleneglycol, calamine, calcium acetate, carbomer, ceresin, ceteareth-20, Cetearyl alcohol, ceteth-2, cetyl alcohol, cetylpalmitate, chlorothymol, citric acid, a solution of coal-tar, diazolidinylurea, Dimethicone, sulfosuccinate dictinary, diphenhydramine HCI, disodium EDTA, chloride distearyldimonium, edetate disodium, etokxidiglicol, flavors, glycerin, literallayout SE, glyceryltrinitrate, hypromellose, hydroxypropylcellulose, iodopropionic, isobutane (propellant), isopropanol, isopropyl alcohol, isopropylmyristate, isopropyl, isostearate, karaya, lanet-16, lanolin, Laureth-23, lidocaine hydrochloride, maltodextrin, menthol, isopropyl alcohol, methylglycol-20, methyl salicylate, methyl paraben, mineral oil, oat flour, octoxinol-9, olive oil, panthenol, oleate PEG-20, petrolatum, polyethylene glycol, Polysorbate 40, potassium hydroxide, potato dextrin, BCP-1 Trideceth-6, propylene glycol, propylparaben, SD alcohol 38-b, SD alcohol 40, nitrilacrilic copolymer, sodium borate, clearesult sodium, sodium chloride, sodium citrate, sodium lauryl sulfate, stearic 2 steareth-21, steer the new acid, stearyl alcohol, styrene/acrylate copolymer, sulfonated castor oil, thymol, titanium dioxide, tocopherylacetate, triethanolamine, various coloring agents, water, white petrolatum, white wax, zinc oxide, zinc pyrithione, paraffin wax, yellow wax, maltodextrin, and a variety of fruit, vegetable, mineral and vitamin extracts.

The present invention provides new formulations anti-itching, through which the bioactive glass is introduced into a combination of any of the above ingredients.

Antibacterial, antiseptic, antibiotic drugs and first aid

The present invention provides new formulations with which the bioactive glass is introduced into various sorts of antibacterial, antiseptic, antibiotic medicines and first aid equipment, for example, in a market the products under the trade names Absorbine,-D, Baciguent, Bactine, Bag Balm, Ben Gay, Betadine, Betasept, BFI, Blue Star, Boil Ease, Brite Life, Campho-Phenique, Carraklenz, Clinipad, Clocream, Dermoplast, Dyna-hex, Family Medic, Flex-All, Fougera, Glover's, Gold Bond, Good Sense, Hibiclens, Hibistat, Humco, Iodex& Johnson, Lanabiotic, Lanacort, Lander, Lanocane, Lavocal, Medi-Quik, Mentholatum, Mineral Ice, Myciguent, Mycitracin, Neosporin, Nexcare, Polysporin, Resinol, Sayman, Sensogard, Spectrocin, Sportscreme, Stopain, Swan, Top Care, Unguentine, Vicks, Zephiran Chloride, as well as the products produced by leading manufacturers.

Typically, antibacterial, antiseptic, anti-Christ. iticheskie drugs and first aid contain alcohol, hydrogen peroxide, regards-iodine, phenol or resorcinol.

As the active ingredients, antibacterial, antiseptic, antibiotic drugs and first aid contain combinations of polymyxin b sulfate, bacitracin zinc, neomycin and hydrochloride pramoxine.

Antibacterial, antiseptic, antibiotic drugs and first aid can also contain one or more of the following inactive ingredients: bacitracin, chloride benzalkonium, benzoic acid, formiate bismuth, butylparaben, camphor, cholesteatoma ointment, citric acid, Dwuosobowy sodium phosphate, dimitriades, emulsifying wax, isopropyl alcohol, hydrochloride lidocaine, glycerin, hydrogen peroxide, imidurea, light mineral oil, magnesium carbonate, menthol, methylparaben, microcrystalline wax, octoxinol-9, vaseline, phosphoric acid, poloxamer 188, polymyxin b sulfate, sort potassium, pramoxine HCI, propylene glycol, silicon dioxide, sodium benzoate, sodium lauryl sulfate, sodium metabisulfite, thymol, tocopherylacetate, water, white petrolatum and phenolsulfonate zinc.

The present invention provides new formulations of antibacterial, antiseptic, antibiotic medicines and first aid equipment resulting from the introduction of bioactive glass into a combination of any read is certain of the above ingredients.

Formulations containing fine-grained bioactive glass is a composition that is able to dramatically reduce the time required for healing and significantly strengthen the natural healing process. The effect of the considered formulations can most clearly be illustrated in the patients with complications of the immune system, which significantly suppressed the ability to heal wounds.

Fine bioactive glass, which can be used to treat wounds, burns and various abrasions, usually has the following composition, expressed in weight percent:

Component Percentage
SiO2 40-60
CaO 10-30
Na2O 10-35
P2O5 2-8
CaF2 0-25
In2About3 0-10
To2About 0-8
MDO 0-5

Below is preferred composition of the bioactive glass:

SiO2 45
CaO 24,5
PA2About 24,5
P2O5 6

Featured preferred interval of the particle size of the bioactive glass has a value of less than 90 microns. Can be used particle size less than 10 microns, and a particle size less than 2 microns. Particles of such small size usually have efficiency and does not give any undesirable immune responses.

Antibiotics local actions are antibiotics used to treat skin. Examples of such antibiotics include: chloramphenicol, chlortetracycline, clindamycin, kliohinol, erythromycin, framycetin, gramicidin, fusicology acid, gentamicin, mafenide, mupirocin, neomycin, polymyxin B, bacitracin, silver sulfadiazine, tetracyeline and chlortetracycline. The specialist in this area should be clear that there are other antibiotics as appropriate local action, for example, those listed in U.S.P.D.

Bioactive glass and antibiotic local actions can be used in any pharmaceutically applicable carrier to facilitate application on wounds, burns or abrasions. Such compositions can be used in conjunction with ointment, white petrolatum, mineral oil and other substances known to the expert in this field.

The composition of the bioactive glass and antibiotics can is also be combined with other means of wound care, burns or abrasions, such as collagen, fibrin, fibronectin, vitamin E, gauze, cotton, cellulose, synthetic dressings for the treatment of wounds or burns, as well as other means known to the person skilled in the art. It can also be made of fiberglass and fiberglass from bioactive glass.

Bioactive glass may also be used in skin grafts, and fine-grained, biostable added to the graft before putting in the right place. Before applying the graft can be further processed by local antibiotic action. The use of biostable in the grafts involves increasing the probability of “survival rate” of the graft and its introduction into a patient's body.

Not limited to a particular theory or mechanism of action, it is assumed that the high surface area and reactivity of fine-grained bioactive glass facilitate the excretion of sodium, which increases the pH and increases the amount of oxygen in wound and burn at a lower pH value without such processing. Application of bioactive glass accompanied antimicrobial action, and its joint use of antibiotics increases the effect of the latter in the activation of various growth factors involved in regenerate the tissues. Such reactions lead to the generation of high negative charge on the surface of the glass and the development of high specific surface area (for example, 0.5 m2/2G 12 hours) with involvement in the reaction of collagen, fibronectin and cells. In addition, bioactive glass promotes the deposition of calcium and phosphorus originally present in wound exudate and blood that provides rapid formation of a layer of calcium and phosphate, which may include collagen, fibrin and fibronectin with fast and efficient stabilization of the wound. In some cases, wounds, burns and abrasions saulawa using the composition and method of the present invention without the formation of scabs. In these cases there is a direct formation of new epithelial tissue.

When using bioactive glass in combination with an antibiotic, it is preferable to mix the fine bioactive glass and antibiotic immediately before application to the wound, burn and abrasions. Bioactive fine glass and antibiotic local action can fit in a two-chamber system in which they are mixed and simultaneously applied to the injury site. For this purpose can be used, for example, a syringe of two parts with two separate chambers for storing and mixing chamber. Can be used, etc the many two-element system. So, for example, fine-grained bioactive glass can be added to dressings and antibiotic local actions can be applied on a wound, burn or abrasion followed by application of the dressing material. Can be used and other two-element distributive system.

Soap and bath salt

The present invention covers a new recipe, with which the bioactive glass is put into different varieties of Soaps for the shower and bath in the shape of a bar, liquid, and gel, and bath salt, for example in market products, manufactured under the trade names of Abra, Alba Botanica, Albolen, Aloe Vera 80, Alpha Hydrox, Aroma, Aura Cacia, Aussie, Aveeno, Baby Magic, Balmex, Bare Elegance, Basis, Body & Earth, Bodycology, Bubble Factory, Burt''s Bees, Calgon, Camay, Capri, Caress, Carrington, Cashmere Bouquet, Cetaphil, Clariol, Clearasil, Clearly Natural, Coast, Conti Castile, Cuticura, Dermalab, Desert Essence, Dial, Dove, Earth Therapeutics, Eucerin, Exorex, Fa, Pels Naptha, Formula 405, Gillette, Grandpa's Humco, Irish Spring, Ivory, Jason, Jean Nate, Jergens, Jhonson &Jhonson, Jhonson's, Keri, Kirks Castile, Kiss My Face, Lava Lever 2000, LifeBuoy, Lindora, Lowila, Lubriderm, Lux, Masada, Moisturel, Nate' Naturals, Naturade, Nature's Gate, Neutrogena, Nivea, No Rinse, Noxzema, Oil of Olay, Oilaturm, Packer's, Palmolive, PanOxil Bar, Phisoderm, Polytar, Purell, Pure&Natural, Pure Pleasure, Purpose, Revlon, Safeguard, San Francisco Soap, Sarah Michaels, Sayman, Shield, Shikai, Simply Be Well, Softsoap, Stiefel, St. Ives Swiss Formula, State of Mind, Suave, Summer's Eve, Soddyboye, The Healing Garden, Tom's of Main Tone, Ultra Swim, Vaseline, Vel Beauty Bar, Village Naturals, White Raine, Yardley''s of London, Zest, and products produced by leading manufacturers.

Against the microbial properties of bioactive glass are particularly useful for soap recipes. In addition, the production of soap is a process carried out in an anhydrous environment, obtaining these recipes is a relatively straightforward process. Bioactive glass with a certain particle size has an abrasive effect and is particularly suitable for certain varieties of Soaps for hands (for example, "Java"). The facial wash can be used bioactive glass in the form of spherical particles, like polymeric beads, which is part of some cleaners entity.

Anti-inflammatory properties of bioactive glass are particularly useful for use in tampons and tampon products against itching. These new products to reduce redness and skin irritation.

Usually soap for the shower and bath in the shape of a bar, liquid and gel as well as bath salt contain sodium hydroxide or ammonium, taly fat, coconut oil or palm oil seed and fragrances.

Traditional formulations of Soaps for the shower and bath in the shape of a bar, liquid and gel as well as bath salts contain triclocarban, soap, tallowate sodium, sodium palmitate, Cocoate sodium, various kinds of palm kernelate, water, methyl ether PEG-6, methyl ether, fragrance, glycerin, sorbitol, sodium chloride, tetranitro Atisreal, pendantry pentetate, BHT and various coloring agents.

Soap, bath and shower in the shape of a bar, liquid is ti and the gel may also include one or more of the following substances: chloride acetaminophenramadol, alkilammonia polyester alcohol, allantoin, aminomethylpropanol, Laureth sulfate ammonium lauryl ammonium chloride behenamidopropyl rd-dimonium, benzophenone-4, BHT, Biotin, boric acid, C12-15 alkylbenzoic, calcium Pantothenate, carbomer, cetyl alcohol, chromium hydroxide green, cocamide DEA, cocamidopropyl, cocoa butter, kombatan PEG-18, cochlearimplant, fatty acid of coconut, corn oil, cottonseed oil, disillusioned, diazolidinylurea, Dimethicone, dimethiconol copolyol, disodium, Cocoyl, disodium EDTA, centripetal, EDTA, etokxidiglicol, ethyl alcohol, atedonova acid heteronomy acid, literallayout, glycol stearate, glycolipids, chloride guar of hydroxypropyltrimonium, hexyleneglycol, hydrolyzed silk protein, hydroxypropyl, hypromellose, imidazolidinethione, iodopropionic, isopropylmalate, isopropylmyristate, lanolin oil, lauramide DEA, lauramide MEA, Laureth-10, Laureth-23, lauric acid, lauric alcohol, lauryl sulphate, lecithin, lemon juice, linoleamide DEA, cocat magnesium, magnesium laurate, magnesium stearate, methylglycol-10, methylglycol-20, methylcellulose, Methylchloroisothiazolinone, the combination, methylparaben, mineral oil, oleate/cocat, alerby alcohol oreillettes, palm acid, palmitic sour is a, paraffin, PEG the propylene glycol oleate, literallayout PEG-7, PEG-12, dioleate PEG-120 methylglucose, PEG-20, distearate PEG-3, PEG-5, PEG-75, PEG-8, PEG-90M, vaseline, Phenoxyethanol, polyquaternium-10, polyquaternium-22, Polysorbate 20, GPR-5-ceteth-20, propylene glycol, propylparaben, retinilpalmitat, silk peptide, sodium benzoate, sodium citrate, cagliaricalcio.net sodium, makelparam sodium, cocoylisethionate sodium, dodecylbenzenesulfonate sodium, sodium formate, sodium hydroxide, isethionate sodium, sodium laurate, sodium Laureth sulphate, laurolactam sodium, lauroylsarcosine sodium, myresult sodium, palm kernelate sodium, ricinoleic sodium, sodium stearate, sodium styrene/acrylate copolymer, sodium stirolakrilat/divinylbenzene copolymer, sodium sulfate, Foradori stearamidopropyl PG-dimonium, stearic acid, sunflower oil, taly acid, teacherinsight, tea-oleate, tea-stearate, titanium dioxide, tocopherylacetate, triclosan, C14-16 reincorporate sodium, triethanolamine, trinacria EDTA, trinacria etidronate, trinacria HEDTA, ultramarine blue, sodium Laureth sulphate, water laurilsulfosuktinat disodium, cocamidopropyl betaine, sodium Laureth-13 carboxylate, flavors, glycerin, panthenol, aloe gel, ammonium chloride, DMDMH the as distearate PEG-150, distearate glycol, citric acid, polik eternium-7, cocamide MEA, tetranitro EDTA, Laureth-7, various coloring agents, as well as various plant, mineral and vitamin extracts.

The present invention provides new formulations of Soaps for the shower and bath in the shape of a bar, liquid, and gel, and bath salts that get the introduction of bioactive glass into a combination of any of the above ingredients.

Shampoos for easy combing hair, mousse for hair, hair gel and hair spray aerosol

The present invention includes new recipes, by which the bioactive glass is introduced into a variety of shampoos for easy combing hair mousses, hair gels, hair and aerosol hair sprays, for example in market products under the trademarks Adorm, Agree, Alberto V05, Allercreme, Aloe Vera 80, American Crew, Aqua Net, Aussie Land, Baby Magic, Baksam, Breck, Btite-Life, Brylcreem, Citre Shine, Clairol, Color Soft, Condition 3-in-1, Consort, Cortexx, DeepEarth, Denirex Dep, DHS, Dippity-Do, Look Dry, Dry Style, Elta, European Mystique, Final Net Finesse, Flex, Free and Clear, Freeman, Freeze It, Frizz Control, Frizz Ease, Garden Botanica, Gillette, Good Sense, GrOOm Clean, Hask, Head&Shoulders, Henna Gold, Herbold, Infusium 23, loni T, Ivory, Jasson, Jeris, Jheri Redding, Jhirmack, Jhon Frieda, Jhonson &Jhonson, Jhonson's, Joico, Kiss Kids, Kiss My Face, La Bella, L.A. Looks, Landers, Looney Tunes, L'oreal, Loving Care, Marci Gelle, Mane'n Tail, Mink Difference, Nestle, Neutrogena, Nexxus, Nizoral, No Rinse, Ogilvie, Pantene, Paul Mitchell, Perma Soft, Pert Plus, Physique, Pinaud, Protein 29, Pro-V, Prell, Progaine, Queen Helene, Rave, Redken, Revlon, Royal Crown, Russ Kalvin''s Generic,Salon Grafix, Salon Selective, Salon Style, Scalpicin, Sebstian, Sebucare, Sebulex, Sebutane, Selsun Blue, St. Ives Swiss Formula, Stiff Stuff, Style, Suave, Superset, Tegrin, The Dry Look, Theorie, Thermasilk, Thicker Fuller Hair, Tigi, Tom's of Maine, Top Brass, Tres Flores, Tresemme, Ultimate Look, UltraSwim, University Medical, Vaseline, Venture, Vidal SassoOn, Vital Care, Vitalis, White Raine, Wildroot, Willow Lake, Youth Hair, Zincon, as well as the products produced by leading manufacturers.

Usually shampoos and tools to help detangle hair, contain laurylsulphate ammonium, triethanolamine, lauramide DEA, lecithin, glycol stearate, methylparaben and methylisothiazoline.

Bioactive glass and Sol-gel derived bioactive glass can react with water environments with the formation of the solution, enriched with such inorganic elements such as calcium, phosphorus, sodium and silicon. Introduction bioactive glass in such hair care products provides the deposition of these inorganic elements on the hair with the formation of mineralogical layer (e.g., hydroxyapatite). It is assumed that such mineralogical layer strengthens hair and possibly improves “softness” and “style” hair styling. In addition, the bioactive glass has an anti-microbial effect, which reduces the formation of dandruff.

Traditional formulations of shampoos and tools for easy combing hair, include water, Laureth sulfate ammonium lauryl ammonium, distearate glycol, DIMET the con, cocamide DEA, cetyl alcohol, fragrances, polymethacrylamide, chloride trimonium, sodium citrate, DMDMH the as sodium chloride, PEG-14M, digidrirovanny calamityville, disodium EDTA, Phenoxyethanol, citric acid, metildibromoglutaronitril, ecological ammonium and various coloring agents.

Shampoos and tools for easy combing hair can also contain one or more of the following substances: 2-oleamide-1,3-octadecanethiol (ceramide-r), ndimethylacetamide MEA, acrylate/C10-30 alkylacrylate crosspolymer, polymeric acrylic acid (carbomer 1342), alcohol, gel aloe extract, octenylsuccinate aluminum-starch, amodimethicone, arginine, benzophenone-3, benzophenone-4, Biotin, bottled hydroxytoluene, butyleneglycol, butylparaben, carbomer, carboxylic acid chloride ceremony, chloroxylenol, the distillate of coal tar, cocamide DEA, cocamide MIPA.cocamidopropyl betaine, cocamidopropyl hydroxysultaine, the oxide cocamidopropylbetaine, kombatan, hydrolyzed hair keratin hydroxypropyl cocodimama, chloride catrimani, cyclomethicone, cysteine, DEA-methoxycinnamate, metilpolisiloxana, diazolidinylurea, dimethiconol, dimethyl ether, disodium cocoamphodiacetate, disodium laurilsulfosuktinat, disodium lauroamphodiacetate, disodium, oleamide MEA sulfosuccinate, di is the atrium phosphate, disodium ricinoleic, ergocalciferol, ethylparaben, distearyldimonium chloride glycerin, glycerin, glycol stearate, glycosaminoglycans, chloride guar hydroxypropyltrimonium, hydrochloric acid, hydrolyzed animal protein, hydrolyzed collagen, hydrolyzed keratin, hydrolyzed silk, hydrolyzed vegetable protein, hydrolyzed wheat protein, hydrolyzed wheat starch, hydrolyzed yeast, chloride, hydroxypropyl guar hydroxypropyltrimonium, hypromellose, hydroxypropyltrimonium hydrolyzed wheat protein, imidazolidinethione, Inositol, adpropinquabant, adpropinquaverant, isobutane, isolaureth-6, lactate isostearamide the research, keratin amino acids, ketoconazole, lactamide MEA, lauramide DEA, laurabolin, Laureth-10, Laureth-23, Laureth-4, Laureth-6, lauric alcohol, lecithin, magnesium citrate, magnesium Laureth sulphate, measurement, menthol, methenamine, methoxypropylamine, Methylchloroisothiazolinone, the combination, methylparaben, mica, octoxynol-40, octyldodecyl RAVA, activitiesthat, octylmethoxycinnamate, chloride aleamoni, palmitic acid, one, panthenol, ethyl ester penttila, Pantothenic acid, PEG-12, dioleate PEG-120 methylglucose, PEG-15 comporium is h, distearate PEG-150, PEG-23M, PEG-27 lanolin, oleate PEG-55 propylene glycol, PEG-60 almond glycerides, PEG-600, glycerinated PEG-7, laurate PEG-80 sorbitan phosphoric acid, phytantriol, phytic acid, polyquaternium-16, polyquaternium-10, polyquaternium-11, polyquaternium-30, polyquaternium-4, polyquaternium-46, polyquaternium-7, Polysorbate 20, Polysorbate 80, potassium Cocoyl hydrolyzed collagen, potassium sorbate, BCPs-12 may be-16, BCPs 5 Laureth 5, GPR-9, propylene glycol, propylparaben, pyrithione zinc, quaterni-15, quaterni 22, quaterni-75, quaterni-80, retinilpalmitat, ethosulfate retinylidene-acidimage, SD alcohol 40, whey protein, silk amino acids, silk protein, silsesquioxane copolymer, sodium benzoate, C14-17 alkyl SEC sulfonate sodium, cookilaria sodium, monosodium glutamate, sodium hydroxide, hydroxymethylglycinate sodium Laureth sulfate sodium Laureth-13 carboxylate, sodium, lauramidopropyl sodium, lauroylsarcosine sodium, sodium lauryl sulfate, sodium methylparaben, sodium myresult resultat sodium, sodium phosphate, sodium styrene/acrylate/divinylbenzene copolymer, sodium sulfate, trilateralist sodium, extract solubilizing coal tar, soluble collagen, soy amide DEA, stearyl alcohol, tallowy-60 maristhill, Thea-dodecylbenzensulfonate, Thea-dodecylbenzensulfonate, Thea-La is resultat, tetranitro EDTA extract, tissue fluid, titanium dioxide, tocopherylacetate, a solution of tar, Trideceth-12, lauryl sulfate, triethanolamine, trimethylsilylamodimethicone, wheat oligosaccharides, aminopropyldimethylamine wheat germ, xanthan gum, yeast extract, hydrolyzed soy protein, sodium PCA, etokxidiglicol, phosphate chloride linoleamide PG-demonia, hydrogenated polydecene, trimethylolpropane, Phenoxyethanol, and a variety of fruit, mineral and vitamin extracts.

The present invention provides new formulations of shampoos and tools for easy combing hair, by introducing a bioactive glass into a combination of any of the above ingredients.

Usually mousse for hair, hair gel and aerosol hairspray contain mineral oil, lanolin, stearic acid and zinc pyrithione.

Traditional recipes hair mousse, hair gel and aerosol hairspray contain water, isobutane, polyquaternium-4, propane, propylene glycol, C9-11 pareth-8, DMDMH the as, perfume, panthenol, disodium EDTA, pateneletronic ether, the one, the oxide lauramine, keratin amino acids and citric acid.

Mousse for hair, hair gel and aerosol hairspray can also contain one or more of the following substances: ndimethylacetamide MEA, acrylate sprinklers the measures acrylate/Dimethicone/ methacrylate copolymer, alanine, denatured alcohol, allantoin, aminomethylpropanol, aminomethylpropanol, ammonium benzoate, ammonium hydroxide, amodimethicone, arachidonic acid, ascorbyl palmitate, Bekenova acid, benzophenone-3, betaine, boric acid, butyl ester of PVM/MA copolymer, C13-14 isoparaffin, pattent calcium, carbomer, carbopol, catalase, tetereluctant, ceteth-16, ceteth-20, methyl ceremony, chloride ceremony, cetyl alcohol, chlorhexidine dihydrochloride, cocamide DEA, cocamidopropyl betaine, cocamidopropyl hydroxysultaine, collagen, cyclomethicone, DEA-methoxycinnamate, diazolidinylurea, diisobutylamine, dimethiconol copolyol, dimethiconol, dimethyl ether, isostearic dimethylamine, dimethylstyrene, dioctylsebacate, chloride distearyldimonium, ethosulfate, ethyl ester copolymer (PVM/MA, ethyldimonium, gelatin, glutamic acid, glycerol, glycine, hyaluronic acid, HFC 152A, hydrolyzed elastin, hydrolyzed soy protein, hydrolyzed wheat protein, hydrolyzed wheat starch, hydrophilic polyester polyurethane, hydroxyethylcellulose, hydroxypropanoyl, hydroxypropylmethyl-cellulose, adpropinquaverant, isododecane, isopropyl alcohol, isostearic-10, keratin protein, lactamide MEA, lanet-16 lauramide DEA, lauramide MEA, Laureth-11, Laureth-23, Laureth-4, Laureth-7, Laureth-9, lecithin, linoleamide, linoleic acid, lysine, chloride lysine hydroxypropyltrimonium, Methylchloroisothiazolinone, Methylisothiazolinone, combination, methylparaben, mineral oil, myristoyl hydrolyzed collagen, Niacinamide, SD alcohol 40, nonoxynol-10, activitiesthat, octisalate, octylacrylamide/acrylate copolymer, octylacrylamide/acrylate/butylaminoethyl met, octylmethoxycinnamate, chloride realtone, oleic acid, IG 20 IG-16, palmitic acid, palmitoylcarnitine, PEG-15 comingore, PEG-40 gidrirovannoe castor oil, PEG-6 cocamide, PEG-60 gidrirovannoe castor oil, PEG-75 lanolin, PEG-8, sorbitol, Phenoxyethanol, fenitrothion, phospholipids, phytantriol, polyacrylamide, polyquaternium-11, polyquaternium-46, polyquaternium-7, Polysorbate 20, Polysorbate 80, Poliziano 4 pandanifolia copolyol dimetikona potassium, potassium hydroxide, potassium sorbate, GPR-12-PEG-50 lanolin, GPR-5-ceteth-20, GPR-9 diethylammonium chloride, Proline, PVP (PVP), pyridoxine HCI, quaterni-15, retinilpalmitat, ribonucleic acid, serine, silk amino acids, silk protein, sodium benzoate, C13-15 pareth-8 butylphosphate sodium C13-15 pareth-8 phosphate sodium C14-16 reincorporate sodium, sodium chloride, cocoylisethionate sodium, hydroxymethylene is at sodium (amino acid derivative), sodium PCA, sorbitol, soy amide DEA, chloride stearalkonium, steareth-16, steareth-2, stearic acid, stearyl alcohol, tea-dodecylbenzenesulfonate, tetranitro EDTA, threonine, tocopherylacetate, Trideceth-12, triethanolamine, triisopropanolamine, urethane/C1-20 PEG alkilany copolymer, VA/crotonate/vinyl/neodecanoate copolymer, various fruit, vegetable, vitamin extracts, ethosulfate-acidimage wheat germ, yeast extract, isobutane, AMR-isostearoyl hydrolyzed soy protein, butyleneglycol, and SD alcohol 40.

The present invention provides new formulations of hair mousse, hair gel and aerosol hairspray that get the introduction of bioactive glass into a combination of any of the above ingredients.

Antimicrobial properties and pH effects of bioactive glass are particularly useful for shampoos and other hair care products, because they contribute to the reduction of bacterial contamination and normalize the pH value of the hair. In addition, the ability of bioactive glass to highlight the minerals that are associated with the surface of the hair, and contributes to improving the strength of the hair, increasing their mass and volume.

The following examples 11-13 illustrate embodiments of the formulations of shampoos containing bioactive glass, including Sol-gel produced in the aqueous bioactive glass.

Example 11

The composition of the shampoo containing bioactive glass

INGREDIENTS % mass
Standapol ES-2 30,0
Crosutaine C-50 10,0
Foamid 5,0
Deionized water 47,3
Jaguar C-14S 0,5
Phenobact 1,0
Odorant (Wildberry AFF#24551) 0,2
Powder citric acid monohydrate 3,0
Bioactive glass SCHOTT (environments. the particle size of <4 μm) 3,0
  100,0

Example 12: Shampoos containing glass 45s5 (three different compositions: CPD3-15A, b, C, D)

INGREDIENTS A,% In, % C,wt% D,%
  mass mass   mass
Standapol ES-2 30,0 30,0 30,0 30, 0
Crosutaine C-50 10,0 10,0 10,0 10, 0
Foamid 5,0 5,0 5,0 Deionized water 48,0 48,0 48,0 48,0
Phenobact 1,0 1,0 1,0 1,0
Powder monohydrate citric 1,0 - 1,0 -
acid        
The SCHOTT glass 45s5(environments. size 5,0 - - 5,0
particles <4 μm)        
  100,0 94,0 95,0 99,0

Example 13: Shampoos containing bioactive glass (three different compositions: CPD3-31 a, b, C, D)

INGREDIENTS A,% In, % C,wt% D,%
  mass mass mass
Steol Cs-230 30,0 30,0 30,0 30,0
Crosutaine C-50 10,0 10,0 10,0 10,0
Foamid 5,0 5,0 5,0 5,0
Deionized water 49,0 48,0 47,0 46,0
1,0 1,0 1,0 1,0 1,0
Powder citric acid monohydrate - 1,0 2,0 3,0
Biostable(environments. the particle size of<5 μm) 5,0 5,0 5,0 5,0
  100,0 100,0 100,0 100,0

The initial pH values

pHo31A - 8,9

pHoV - 8,2

pHo31C - 5,7

pHo31D - 4,8

PH after 24 hours

pH2431A -9,6

pH24V - 9,2

pH24S - 8,5

PH2431D - 7,2

Antiperspirants and deodorants

The present invention includes new recipes, by which the bioactive glass is introduced into a variety of antiperspirants and deodorants in the form of a powder, cream, ball packaging, aerosol and cosmetic pencils, such as the products sold under the trademarks 5 Day, Allercreme, Almay, Aqua Velva, Arm & Hammer, Arrid XX, Ban, Banish, Brut, Certain Dri, Clerly Fresh & Natural, Crystal Clean, Crystal Stick, Degree, Desert Essence, Dove, Dry Idea, English Leather, Gillette, Hi & Dri, Jason, Jockey Club, Kiss My Face, Lady Crystal, Lady Mitchum, Lady Speed Stick, Lady's Choice, Mennen, Mitchum, Nair, Nature's Gate, Nautica, Nullo, ld Spice, Pinaud, Power Stick, Revlon Hi 7 Dri, Pight Guard, Secret, Soft & Dry, Speed Stick, Suave, Sure, Teen Spirit, Tom's of Maine, Tussy, Soft &Dri, Yodora, as well as the products produced by leading manufacturers.

Antimicrobial and hygroscopic properties of bioactive glass in the formulation of deodorants and antiperspirants help to destroy the bacteria causing the odor, whereas anti-inflammatory properties soothe irritation. Bioactive glass may be introduced in solid amorphous form, like deodorant “crystals”. Washing agent containing polished solid form, also possess antimicrobial action.

Usually antiperspirant and deodorants contain aluminum chlorohydrate, aluminum chloride, chlorides of zirconium or triclosan.

Traditional recipes of antiperspirants and deodorants in the form of pencils, ball packaging, aerosols, creams, pads and powders contain as active ingredients aluminum zirconium tetrachlorohydrex gly or aluminum chlorohydrate.

Antiperspirants and deodorants can also contain one or more of the following substances: alkoxy, alcohol, allantoin, aloe Vera gel, aluminum chloride, butyl ether, PEG-14, cyclomethicone, sodium bicarbonate, beganovic alcohol, benzethonium chloride, benzoic acid, BHT, C12-15 alkylbenzoic, triglyceride C18-36 acid, color is aret-20, Cetearyl alcohol, citric acid, corn starch, cyclomethicone, Cyclopentasiloxane, cyclotetrasiloxane, dibenzylidene, dicaprylate/dicaprate, diisopropylamide, Diisopropylamine, Dimethicone, dipropyleneglycol, L panthenol, farnesol, flavors, glycerin, glyceridae, glycerylmonostearate, hectorite, HFC 152A, gidrirovannoe castor oil, hydrogenated polyisobutene, gidrirovannoe vegetable oil, hydroxyethylcellulose, isobutane, isopropyl alcohol, isopropylmyristate, Laureth-4, methylparaben, mineral oil, myristoleate, octoxynol-9, octyldodecanol, octylpyrimidine, octyldodecanol, stearate PEG-100, PEG-20 stearate PEG-25 propylene glycol, distearate PEG-8, pentadecagon, vaseline, PG, fenitrothion, glycol, polyol, polysaccharides, Polysorbate 20, Politiken, potassium oxide, potassium sorbate, butyl ether GPR-14, Laurelville ether BCP-1-PEG-9, propane, propylene carbonate, propylene glycol, propylparaben, purified clay, quaterni-18, SD alcohol 40, silicon dioxide, silk powder, bicarbonate of sodium, Laureth 13 carboxylate, sodium, sodium stearate, ethosulfate sojati morpholine, starch, stearyl alcohol, talc, tert-butyl alcohol, tert-butylhydroquinone, tetranitro EDTA, tribehenin, triclosan, triethylcitrate, urea, various coloring agents, various m is the mineral and vitamin extracts, vegetable oil, vegetable starches, water, xanthan gum, zinc oxide.

The present invention provides a new formulation of the antiperspirant and deodorant, obtained by the introduction of bioactive glass into a combination of any of the above ingredients.

Antimicrobial, anti-inflammatory and hygroscopic properties of bioactive glass are particularly useful for antiperspirant and deodorant means supporting the destruction of bacteria, odor and moisture.

Lotions after shaving and shaving

The present invention covers a new recipe, with which the bioactive glass is introduced into a variety of lotions and after shave, such as the products sold under the trademarks Aceite, Afta, Aqua Velva, Aspen, Brut, Bump Figter, Burt" Bees, Earth Science, Edge, Flents, Gillette, Hoyt Co., Ice Sport, lodex, Jason< Joven, Mennen, Old Spice, Pinaud, Pomada, Requa, Samborns, Saxon, Skin Bracer, Super macho, Williams, and products produced by leading manufacturers.

Formulation of lotions and after shave containing bioactive glass have excellent anti-inflammatory effect, reduces skin irritation after shaving.

Usually lotions and after shave contains propylene glycol, menthol, and benzoic acid.

The traditional formulation of lotions and after shave contain SD alcohol 40, water, glycerin, menthol, perfume, be softon-1 and various coloring agents.

The lotions and after shave can also contain one or more of the following substances: aloe extract, octenylsuccinate aluminum starch, benzoic acid, benzyl alcohol, BHT, C12-15 alkylbenzoic, carbomer 98, flour maniaci, cyclomethicone, Dimethicone, disodium EDTA, Ethylenediamine, isotetinoiin, isopropylmyristate, methylparaben, ministerpresident, panthenol, copolymer PEG/BCP-17/6, PEG-60 gidrirovannoe castor oil, PG, Phenoxyethanol, Polysorbate 80, GPR-15, propylene glycol, SD alcohol 39-C, stearyl ether, tetrahydroxypropyl, tocopherylacetate, triethanolamine, various vegetable, fruit and vitamin extracts, xanthan resin, propylene glycol, benzoic acid, benzophenone-2, BHT, PG and benzyl alcohol.

The present invention provides a new formulation of lotions and after shave obtained by introducing a bioactive glass into a combination of any of the above ingredients.

Anti-inflammatory properties of bioactive glass are particularly useful for use in lotions and after shave as substances that reduce inflammation of the skin.

Shave

The present invention covers a new recipe, with which the bioactive glass is introduced into different varieties of shaving products in the form of a cream, gel, powder and Soaps, such as the products sold under targowiskami Afta, Alba Botanica, Aveeno, Barbasol, Brut, Bump Stopper, Burma-Shave, Burt''s Bees, CAM, Colgate, Earth Science, Edge, Everready, Gillette, Jason, Kiss My Face, Lady Legs, Magic, Platinum, Magic Shaving Powder, Noxzema, Old Spice, Palmolive, Pinaud, Remington, Requa, Rise, Shave in the Shower, Skin Bracer, Skinmate, Skintimates, Soft Shave, Tom's of Maine, Williams, and products produced by leading manufacturers.

Usually shave in the form of a cream, gel, powder or soap contain such a humidifier as aloe gel, and this preservative as stearic acid.

Traditional recipes of shaving products in the form of a gel, cream, powder or soap powder contain water, triethanolamine, palmitic acid, stearic acid, isopentane, monoglyceride, sorbitol, PEG-90M, PVP, odorants, isobutane, various coloring agents, as well as various flower, vitamin, and mineral extracts.

Shave in the form of a gel, cream, powder or soap can also contain one or more of the following substances: 1-dodecanol, allantoin, aloe extract, starch, octenylsuccinate aluminum, ammonium hydroxide, barium sulfide, methosulfate behentrimonium, benzaldehyde, benzophenone-1, benzyl alcohol, BHA, BHT, bromelain, Bhutan, C16-C22, calcium carbonate, calcium hydroxide, thioglycolic calcium, carbomer, cellulose polymer, Cetearyl alcohol, cetyl alcohol, chlorhexidine gluconate, corn starch, diazolidinylurea, Dimethicone, Quaternary dimethyls that, dioctylamine, esters of triethanolamine, esters of fatty acids, glycerides, glycerin, glyceridae, literallayout, guanidiniocarbonyl, hydroxyethylcellulose, isopropylmyristate, isopropyl, lanolin alcohol, lanolin oil, Laureth-23, lecithin, menthol, methylparaben, milk protein, ministerpresident, nonoxynol 10, oxidized polyethylene, paraffin, PEG-14M, pentaerythritoltetranitrate PEG-150, capryl/capric glycerides PEG-6, pentane, pendantry pentetate, vaseline, phenylcarbinol, polyethylene, polyquarternium 10, Polysorbate 20, Polysorbate 60, monistat potassium, GPR-12-PEG-65, propane, propylgallate, propylene glycol, propylparaben, resorcinol, retinilpalmitat, SD alcohol 40, soap, sodium benzoate, sodium borate, sodium chloride, sodium lauryl sulfate, metasilicate sodium, myristate sodium stearyl alcohol, TEA stearate, TimeLeft, tetranitro Atisreal, titanium dioxide, tocopherylacetate, triclosan, isobutane, cyclomethicone and C12-15 alkylbenzoic.

The present invention provides new formulations of creams and gels for shaving due to the introduction of bioactive glass into a combination of any of the above ingredients.

The antimicrobial effect of bioactive glass in the means shaving especially useful for killing bacteria and reducing the possibility of infection cutting and cutting the elements during shaving.

Means for waxing and bleaching hair

The present invention covers a new recipe, with which the bioactive glass is introduced into various sorts of depilatory, epilatory and coloring agents in the form of a cream, wax and powder, for example in market products, manufactured under the trade names Andrea, That, Better-Off, Bikini Bare, Hair off Jolen, Nair, Natural, Neet, Nudit, One Touch, Sally Hanson, Zip, as well as the products produced by leading manufacturers.

Typically, funds for depilation, epilation and bleaching hair contain as the active ingredient thioglycolate calcium or calcium hydroxide.

Traditional recipes funds for depilation, epilation and bleaching hair contain water, mineral oil, calcium hydroxide, Cetearyl alcohol, thioglycollate calcium, thioglycolate sodium, ceteareth-20, various floral, herbal and vitamin extracts, and various dyes.

Means for depilation, epilation and bleaching hair can also contain one or more of the following substances: ammonium bicarbonate, chloride benzalkonium, camphor, cetyl alcohol, chamomile extract, citric acid, Dimethicone, odorants, literallayout, hydrogen peroxide, iron oxides, isopropylmyristate, isopropyl, isopropylene, maltodextrin, octoxynol-9, pentaerythritoltetranitrate/capret, who Iselin, phosphoric acid, potassium sorbate, SD alcohol 40, stearamidopropyl dimethylamine, steelsheet, oil of sweet almond, literallayout calcium, octylpyrimidine, stearic acid, propylene glycol, triethanolamine, imidazolidinethione, stearate PEG-100, soluble collagen, lanolin alcohol, disodium EDTA, carbomer, methylparaben, thioglycolate, stereology alcohol and silicon oxide.

The present invention provides new formulations funds depilation, epilation and waxy products obtained by introducing a bioactive glass into a combination of any of the above ingredients.

Anti-inflammatory and antimicrobial properties of bioactive glass make it particularly useful for use in means of depilation, epilation and waxy products, which decreases inflammation, destroys bacteria and eliminates odor.

Toothpaste

Bioactive glass may also be entered in different varieties of toothpastes, such as the products sold under the trade names Act, Aim, Aquafresh, Ann & Hammer, Biore, Bioten, Boiron, Breath Remedy, Brite-Life, Butler, Cepacol, Close-up, Colgate, Crest, Dentu-Creme, Desert Essence, Enamelon, Fixodent, Fresh'N Brite, Gel-Kam, Gleem, Interplak, Keep, Kids Dental Kare, Listerine, Mentadent, Natural White, Nature's Gate, Orajel, Oral-B, Pearl Drops, Pepsodent, Plak Smacker, Plus+White, Pollident, Q-Dent, Rembrandt, Sensodyne, Thermodent, Tom's Maine, Topol, Ultra brite, Ultra Plus, Vademecum, Viadent, as well as roducti, produced by leading manufacturers.

Usually toothpastes contain fluoride, triclosan, pyrophosphates, silicon oxide, sodium bicarbonate, potassium nitrate, as well as natural and/or artificial flavorings.

Traditional formulations of toothpastes contain sodium fluoride, water, sorbitol, hydrated silicon oxide, citrate trihydrate zinc, sodium lauryl sulfate, SD alcohol 40, flavor, cellulose resin, saccharin sodium, and various coloring agents.

Toothpaste can also include one or more of the following ingredients: Acesulfame potassium, aluminum oxide, ammonium chloride, beta-d-glucose, calcium peroxide, calcium sulfate, carbomer, carboxymethylcellulose, citric acid, coenzyme Q10, dihydrate dicalcium phosphate, glycerin, hydrogen peroxide, lactoperoxidase, glucose oxidase, secrete lysozyme, magnesium chloride, methylparaben, microdent poloxamer phosphate, papain, PEG-300, PEG-60, gidrirovannoe castor oil, PEG-12, PEG-32, PEG-6, PEG-75, phosphoric acid, poloxamer 407, poloxamer 1220, potassium nitrate, potassium sorbate, potassium thiocyanate, propylene glycol, propylparaben, pyrophosphate, SD alcohol 38-B, silicon dioxide, simethicone, sodium benzoate, sodium bicarbonate, sodium carbonate, carrageenan sodium, sodium chloride, sodium citrate, sorbitol and related polyols, sodium hydroxide, lauroylsarcosine sodium, m is nitrophosphate sodium, percarbonate sodium, sodium phosphate, sodium tripolyphosphate, terkaly pyrophosphate, tetranitro pyrophosphate, titanium dioxide, trisodium phosphate, PEG-8, various natural and artificial flavors, xanthan gum, zinc chloride, zirconium silicate, thymol, methyl salicylate, and benzoic acid.

Compositions containing bioactive glass can be used, for example, for the remineralization of enamel remineralization initial stage of development of caries remineralization careenage dentin, caries prevention, arresting caries a reversal of caries, as the action of anti-caries funds, as a preventive coverage dental fissures and hypoplasia of tooth enamel, as toothpastes, handling fluorides, as Denisovich seals, etc. Bioactive glass can be entered in toothpaste, cosmetic pencils, cosmetic bases, gels and restorative material, such as covering material, the protective coating of the pulp of the teeth, etc. Such the composition can also be used to treat surfaces after periodontal surgery in order to reduce the sensitivity of the dentin and enhance adhesion of the gums to the teeth. Consider the active composition in the treatment of various defects associated with dental and other problems, and they are himicheski and physically in contact with the tooth, remineralizer its structure.

Used in the text the term “mineralization” refers to the formation of hydroxyapatite. The formation of hydroxyapatite begins at the moment of impact on the bioactive glass of water solutions. It is assumed that sodium ions (Na+) bioactive glass in biological environments are exchanged for ions of N+, causing an increase in pH. Then there is the migration of calcium and phosphorus from bioactive glass, accompanied by the formation of the surface layer enriched in these elements. As replacement of sodium ions in bioactive glass for hydrogen ions and the solution of the lower zone, enriched with silicon oxide, slowly rises. Over time a layer enriched with calcia and phosphorus, crystallizes on hydroxyapatite material. After that collagen is structurally integrated with appetitnymi the agglomerates. The term “effective remineralizing number” refers to any amount capable of forming hydroxyapatite.

Used in the text, the term “tooth structure” refers to any characteristic or characteristics of the tooth, which include, but are not limited to, tooth enamel, dentin, the structure of the tooth root, cement, root dentin, coronal dentin, any dental treatment, etc.

The following composition, expressed in weight percent of the tah, is an example of a bioactive glass that can be used in the formulations of toothpaste and tooth elixir:

Component Number,%
SiO2 40-60
CaO 10-30
Na2O 10-35
P2O5 2-8
CaF2 0-25
In2About3 0-10
K2O 0-8
MDO 0-5

Such bioactive glasses are effective materials that can interact with the structure of teeth, without causing unwanted immune responses.

Bioactive glass particle size can be used in the formulations of toothpastes and dental elixirs, especially in the case when using a combination of small and very small particles. For example, when using compositions comprising fine particles, able to connect with the structure of the teeth (for example, particle size of less than 90 microns)and smaller particles (for example, less than 10 microns), the larger of these particles stick to the tooth structure and function of ion reservoir is, whereas smaller particles are able to penetrate and stay inside a variety of surface irregularities of tooth structure. The larger of these particles provide an additional source of calcium and phosphorus, resulting in mineralization, or the deposition of calcium-phosphate layer under the influence of the fine particles is further developed. Additional quantities of calcium and phosphorus can vydeliajutsia and get into the whole structure of the tooth and to particles that are connected with the interior or inlet holes of the surface irregularities of tooth structure, such as tooth canals. This in turn ensures the continuation of the reaction and support the growth of smaller particles inside or at the entrance to such surface irregularities, resulting in an effective coating or filling surface defects. Excessive concentration of ions of calcium and phosphorus are needed to continue the reaction of smaller particles, because of the rapid depletion of their ions associated with their relatively high surface area. The larger of these particles will react and identification of ions more slowly and for longer periods of time. In addition, larger particles will be mechanically sanded input areas different in ernstig defects of bone tissue, that promotes the involvement of small particles in the reaction with surface defects.

The described effect is very useful for many applications. For example, in the prevention of cavities and rotting teeth compositions of the present invention is able to penetrate into the depth of the smallest surface defects of bone tissue and provide a continuous supply of ions from the nearest larger particles so that they retain the ability to grow and after depletion of ions contained. The described action is very useful for stopping teeth and dental fissure, and in such cases provides a much more effective seal with long lifetime.

In some applications, use of extremely small particles. For example, a particle size of about 2 microns are used to strengthen the internal tooth of the channels having a diameter of about 1-2 microns. Occlusion of these channels leads to a significant reduction of tooth sensitivity, for example, after periodontally surgery. A particularly effective combination of the considered particle is a mixture containing particles smaller than 2 microns and particles larger than 45 microns.

Such compositions containing bioactive glass, usually do not take time to grasp and difficult washed in the mechanical esterni is when cleaning with a toothbrush, the impact of weak acids contained in food, the interaction with the saliva or other liquid substances that are normally in contact with the teeth. Such compositions are usually well able to withstand considerable mixing, washing with water and a long soak in the saliva within five days. Moreover, a large portion of fine particles does not require time to grasp, because such particles react chemically and stick to dental tissue immediately after contact with such surfaces and fluid normally present in the oral cavity. Although the composition is effective in a single application, the more efficient it can be re-used.

As noted earlier, a relatively small fine particles of bioactive glass does not cause significant immune responses. In addition, they do not usually absorbed by macrophages and do not lose their activity.

Such compositions of bioactive glass are able to create a bioactive layer, forming new structural layer for the long-mineralization of tooth structure. This fact was confirmed using the method of IR-spectroscopy with Fourier transform (FTIR) in the study of re-education hydroxycarbonate apatitovo layer on Denisovich surfaces after treatment compositions, with whom containing a series of bioactive glass.

Consider the composition of the bioactive glass may contain a particle size of about 20 microns, with about 30% of the particles have a size less than 10 microns. Other formulations may contain particles of bioactive glass with an average size of about 10 microns, and at least 25% of the particles have a size less than 2 microns.

Consider the composition can be formed in toothpastes. In fact, these particles are able to replace silicon oxide, which is used in modern toothpastes. Add in steklokompozita fluoride leads to hardening of tooth structure. In addition to the direct use of bioactive glass for bone tissue, such compositions of bioactive glass can be used from the environment on the basis of physiological saline or distilled water. Consider the composition may also be formed in the dental elixirs, gels or may be applied by a dentist in the form of paste.

Consider the composition may find use in the methods of lightening, whitening and teeth bleaching. These methods include contacting the teeth with an effective whitening teeth number of bioactive glass, and in particular, they relate to methods of multiple applications. In each of these applications can be used to 0.02-0.3 g of bioactive glass. Ways to bleach the teeth preservation are in their participation with effective teeth whitening amount of bioactive glass, which exercise twice a day for two weeks or more. The term “number of teeth whitening” generally refers to any number, which leads to clarification, in accordance with the Handbook Vita Shade guide, one or more shades of the patient with the shade before processing darker than A3.5, after 4 weeks of use twice a day for two or more minutes for each application.

Methods of teeth whitening can also be contacting the teeth with an effective whitening teeth number of fine-grained bioactive and biocompatible glass containing an oxide or hydroxide of silicon and, optionally, one or more elements such as K, CA, SB, In, Ti, AI, R, N, or F.

Consider compositions containing bioactive glass, typically include, at least, Na, CA and P, although you can use simple sodium-silicate glass, together with external sources of calcium and phosphate. External source of calcium and phosphate can serve itself saliva, or it can be used specially formed oral hygiene composition.

Adding fluoride compositions containing bioactive glass, increases the resistance of tooth structure. Other examples include Sol-gel glass containing, for example, 40-86% of the mass of SiO2practically does not contain sodium content is the following about 6-36% of the mass of CA and about 2-12 wt% R 2O5.

Can also be used in compositions of bioactive glass containing extremely fine particles. So, for example, can be successfully applied to particles whose size is on the order of 2 microns. The particle size can be determined using the methods of scanning electron microscopy or by scanning the laser beam (for example, Coulter LS100). As noted previously, the fine glass particles of relatively small size does not cause a significant immune responses. In addition, it is not absorbed by macrophages and retains its activity.

Consider the composition can be formed in such hygienic compositions, as toothpastes, gels, powders, dental elixirs, washing solutions, as well as such means for sucking and chewing like gum, lozenges, tablets and pellets. Such oral hygiene compositions may contain 0.1 to 50 wt% of bioactive glass. Preferred formulations contain 1-25% of the mass of bioactive glass, and even more preferred formulations contain 5-10% of the mass of bioactive stele.

In addition to the active ingredients, suitable oral hygiene compositions may contain conventional carriers, binders, surface active agents, humectants, coloring agents, pigments, agents that prevent the formation of obnova plaque antibacterial agents, agents bioadhesive type, abrasives, action of anti-caries agents, flavorings, sweeteners, fillers, etc.

In the case of formulations for tooth pastes, abrasive material typically includes an amorphous, gel, precipitated or fume silica, particles of plastic, aluminium oxide, calcium carbonate, and zinc phosphate, insoluble metaphosphate and calcium pyrophosphate. Particularly suitable abrasive is silica. Currently in the blasting abrasive toothpastes can be completely or partially replaced by particles of bioactive glass.

In toothpastes can be entered inorganic thickeners, optionally containing silicon oxides, as Cabosil produced by Cabot Corporation, as well as thickening the oxides of silicon, including brand drugs Zeodent 165, manufactured by J.M. Huber. In the composition of toothpastes can also be entered organic thickeners, such as natural and synthetic gums and colloids. Examples of such thickeners can be carageenan (Irish moss), xanthan gum, and sodium carboxymethylcellulose, starch, polyvinylpyrrolidone, hydroxyethylmethylcellulose, hydroxyethylmethylcellulose, hypromellose and hydroxyethylcellulose (co-dried mixture of the microcrystalline cellulosae Osney resin). Inorganic or organic thickener can be added to such compositions with a concentration of 0.05-2 wt%, preferably 0.1 to 1.5 wt%. In oral compositions can also be administered salt supplying fluoride ions, which is the effective action of anti-caries agents, characterized by their ability to release fluoride in the water environment. It is preferable to use such a water-soluble salt, which supplies 10-5000 ppm of fluoride ion, and preferably 1,000 to 1,500 ppm of fluoride ion. Materials of this type include water-soluble alkali metal salts, for example sodium fluoride, potassium fluoride, monitoroff sodium and sodium fluorosilicate. The preferred salt, supplying the fluoride ions is monitoroff sodium.

The pigments may include non-toxic, water-soluble inorganic pigments such as titanium dioxide and green chromium oxides, ultramarine blue, and purple, and iron oxides and water-soluble coloring varnishes obtained by the application of calcium and aluminum salts of dyes, FD&C on alumina, such varnishes as FD&C green #1, FD&C blue #2, FD&C R&D #30 and FD&C yellow #5. These pigments have a particle size in the range of 5-1000 μm, preferably 250-500 microns, and are present in the system with a concentration of 0.5-3% wt. Typically, the dyes are sensitive to the presence of eroxide ingredient and for this reason they are not included in the formulation of toothpaste, although the dye FD&C green #3, as it was discovered, is resistant to fading in the presence of toothpaste Sao2.

Can be used suitable flavoring or sweetening material. Examples of suitable flavoring ingredients can serve as flavoring oils, e.g. oil of spearmint, peppermint, gruenke, sassafras, clove, sage, eucalyptus, marjoram, cinnamon, lemon and orange, and methyl salicylate. Suitable sweetening agents include sucrose, lactose, maltose, sorbitol, sodium cyclamate, pericatin and saccharin sodium. The total number of flavouring and sweetening agents may comprise from 0.01 to 5% or more by weight of the drug.

In the present oral compositions can be various other materials. To them, for example, include preservatives, silicones and chlorophyllose compounds, vitamins such as B6, B12, C, E and K, such antibacterial agents like chlorhexidine, such halogenated diphenyl ethers, such as triclosan, such antisense agents as potassium nitrate, potassium citrate, and mixtures thereof. These adjuvants are entered in toothpastes in quantities that do not have undesirable effects on the desired properties and characteristics, and they are chosen and used in suitable amounts depending on the concrete type of the component.

Methods of obtaining gels, toothpastes, mouthwashes, dental elixirs, resins and gum is well known from the literature. Bioactive glass may be incorporated in such products using various methods, including simple mixing. In some cases it is desirable to protect the bioactive glass from contact with water or other components of distributing media to prevent premature reaction of bioactive glass. This operation can be carried out in a number of ways, including, for example, using a syringe of two elements to the mixing chamber.

Mouthwash and mouth rinse.

The present invention covers a new recipe, with which the bioactive glass is introduced into the various varieties of dental elixirs and means for rinsing the oral cavity, such as the products sold under the trade names Act, Doktor Tichenor, Glyoxide Antiseptic, Betadine, Bioten, Cepacol, Colgate, Good Sense, Lavoris, Listerine, Listermint, Plax, Reach, Rembrandt, Slivart, Scope, Signal, Targon, Tom's of Maine, Viadent, Vince, Weleda, and products produced by leading manufacturers.

Usually dental elixirs and means for rinsing the oral cavity contain fluoride, antibacterial agents, hydrogen peroxide and sodium carbonate.

Traditional recipes of dental elixirs and means for rinsing the oral cavity contain thymol, eucalyptol, medicali ilat menthol, water, alcohol, benzoic acid, poloxamer 407, sodium benzoate, caramel.

Dental elixirs and means for rinsing the oral cavity may also contain one or more of the following substances: aloe Vera, calcium chloride, calcium lactate, chloride, pyridinium, citric acid, bromide of domiphen, gluconolactone, glucose oxidase, glycerol, hydrogenated starch, hydroxyethylcellulose, lactoferrin, lactoperoxidase, secrete lysozyme, magnesium chloride, methylparaben, natural and artificial flavors, nitrogen, poloxamer 237, Polysorbate 20, Polysorbate 80, potassium chloride, potassium phosphate, povidone-iodine, propylene glycol, saccharin, saccharin sodium, SD alcohol 38-B, sodium carboxymethylcellulose, sodium chloride, sodium citrate, sodium gluconate, sodium hydroxide, sodium lauryl sulfate, saccharin sodium, sorbitol, sodium pyrophosphate, various natural and artificial flavors, xanthan gum, xylitol, zinc chloride and zinc oxide.

The present invention provides new formulations of dental elixirs and means for rinsing the mouth resulting from the introduction of bioactive glass into a combination of any of the above ingredients.

In addition to direct application of bioactive glass on the teeth, the composition of the bioactive glass may also be applied from a physiological solution or the funds on the basis of the e distilled water.

Consider oral formulations can be used in conjunction with a source of calcium and/or phosphate in the manufacture of a composition for whitening teeth.

Antimicrobial and abrasive effect of bioactive glass are particularly useful for use in dental elixirs and means for rinsing the oral cavity, designed to fight bacteria and reduce staining.

Eye drops

The present invention covers a new recipe, with which the bioactive glass is introduced into the various varieties of eye drops, such as the products sold under the trade names Medic''s Choice, Alcon, All Clear, Bausch & Lomb, Bio, Tears Naturale, Cler Eyes, Murine Plus, Naphcon, OcuClear, Opcon-A, Prefin, Vasoclear, Visine, and products produced by the leading and reputed manufacturers.

Usually eye drops contain polyethylene glycol 300, nafazolina hydrochloride and chloride benzalkonium.

Eye drops may also contain one of the following substances: boric acid, edetate sodium, water, sodium borate, polyvinyl alcohol, povidone, hydrochloride of tetrahydrozoline, dextrose, disodium EDTA, potassium chloride, water, sodium bicarbonate, sodium chloride, sodium citrate, sodium phosphate, Oxymetazoline HCI, hypromellose, Pheniramine, liquifilm, phenylephrine HCI, sodium acetate, sodium thiosulfate and hydrochloric acid.

the Present invention provides a new formulation of eye drops, get the introduction of bioactive glass into a combination of any of the above ingredients. Care products for contact lenses.

Bioactive glass may also be entered in various sorts of care for contact lenses, including cleaning solutions for hard and soft contact lenses, saline solutions, and solutions for re-wetting, such as the products sold under the trade names of Alcon, Allergen, Barnes Hind, Bausch& Lornb, Boston, Ciba, Clean-N-Soak, Clerz Z, LiquiFilm, Opti-Soak, ProFree, Resolve, Soac-Lens, Wet-N-Soak, Ciba Vision, Complete, Lens Plus Miraflow, Opti-Clen, Opti-Free Opti-Zyme, Pliagel, ReNu, Sensitive Eyes, Ultra Zyme, drugstore.com, computing hardware, Unisol, Clear Eyes, Opti-One, as well as in the products manufactured by leading and leading manufacturers.

Usually care products for contact lenses contain boric acid, sodium chloride, thimersol and edetate sodium.

Care products for contact lenses can also contain one or more of the following substances: chlorine benzalkonium, sulfate Olkiluoto ether, ethoxylated alkyl phenol, tri-Quaternary phospholipid based on cocoa, silica gel, titanium dioxide, perfume, nitrate of finalstate, polivinilovy alcohol, anionic detergents, phosphates of sodium, Polysorbate 80, hydroxyethylcellulose, polyquad, papain, cocoamphocarboxyglycinate, sodium lauryl sulfate, hexyleneglycol, Pancreatin, tyloxapol, sorbic acid is one subtilisin And, polecam 407, amphoteric 10, the stabilizer twin 21, microcosmically, potassium chloride, proteolytic enzyme, sodium carbonate, poloxamine, sodium borate, isotonic, antimicrobial buffer system, perborate sodium, hydrogen peroxide, phosphoric acid, nitrogen, borate buffer solution, water, EDTA, ceramic, glycerin and povidone.

In addition, the bioactive glass may be added or included in eye drops and nasal drops in order to give them improved antibacterial, anti-inflammatory and hygroscopic properties.

In addition, bioactive glass can be entered in tools for polishing nails nails on hands and feet. Anti-inflammatory properties of bioactive glass make it particularly suitable for use in such tools nail care.

In addition, bioactive glass can be used in conjunction with the means for male and female shaving, including, without special restrictions available and electric razors. Bactericidal and anti-inflammatory properties of bioactive glass are particularly suitable for use in such products.

Bioactive glass may also be added or included in such means of caring for the oral cavity, as Ambisol. Anti-inflammatory and and themicrobial properties of bioactive glass can be very useful for these products.

In the example below 14 presents the technical realization of additional prototype of cosmetic formulations comprising bioactive glass, including Sol-gel derived bioactive glass.

Example 14: Additional prototype cosmetic formulations.

The following experienced cosmetic products containing bioactive glass.

1. Melkofokusnoe cosmetic product containing Sol-gel derived bioactive glass powder mixed with a commercially available cream for face. The application of this product on the face there was a reduction of fine lines and wrinkles and strengthen the skin.

2. Shampoo containing 5% of the mass of bioactive glass with a particle size of 4 μm, is formed by a combination of drugs Standapol ES-2, Crosultane C-50, Foamid With deionized water, Fenobact and citric acid.

3. Gel curing/protection nail containing gel-like oil str or glycerol, as well as muln®polymer, or glycerin, water, citric acid, Jaguar C-14S and feeback.

4. Recipes for makeup containing gel-like oil str and Lubrajel®MS with different pigments.

5. Skin lotion/makeup containing Polawax, mineral oil, glycerin, Jaguar C14-S, citric acid, Phenobact, a coloring agent and a flavoring.

6. Sunscreen product containing gel-like oil Jo is both octylmethoxycinnamate and benzophenone-3.

7. Pencil deodorant containing 8% bioactive glass composition MV00/036/02/01.

8. Pencil deodorant containing 8% bioactive glass composition MV00/036/01/01.

9. Pencil deodorant containing 5% bioactive glass composition MV00/030/02/01.

10. Cream deodorant containing 50% of the bioactive glass and the composition MV00/036/03/01.

11. Cream for nail curing, containing 15% of bioactive glass and composition MV00/036/04/01A.

12. Cream for nail curing, containing 30% bioactive glass composition MV00/036/04/01B.

The following example 15 demonstrates the fact that cosmetic formulations containing bioactive glass, including Sol-gel derived bioactive glass, do not cause skin irritation and do not lead to a noticeable allergic hypersensitivity.

Example 15: Testing for sensitizing the skin's ability

Some experimental products (biostable (30%) in the formulation of the oil/water) tested for the occurrence of skin irritation or allergic hypersensitivity after applying any of the experienced cosmetic compositions containing bioactive glass.

Human patch test is a probing, relatively safe and fairly reliable way of identifying allergens. The positive reaction of n is correctly conducted application testing indicates the presence of the test pin sensitivity on the test substance, however, this is not evidence that the test substance induces clinical dermatitis.

When conducting application skin tests possible local allergen penetrates through the stratum corneum into the viable (effector) cells of the skin, which causes stimulation of the immune system.

Methodology: the test product was applied on a piece of filter paper, placed on the impermeable sheet which is secured to the skin using adhesive tape (Leukotest ®, Fa. Hartman). Place of trial: the inner part of the forearm. The test patch was left in place for 24 hours and then deleted.

After that, the object of the tests was subjected to dermatological research. After 48 and 72 hours conducted the second and third examination by a dermatologist.

All assessments were carried out in standard conditions of illumination experienced dermatologist.

The objects of study were instructionals about the need to maintain test sites in the dry state.

Results: under the conditions tested was not received evidence of primary irritation or allergic hypersensitivity. None of the thirty-application tests did not give a positive reaction after 24, 48 and 72 hours. The conclusion was made about the safety of the tested products.

The following examples 16 and 17 presents the re is ulitity test zone of inhibition and demonstrated antimicrobial properties of bioactive glass. Antimicrobial properties of bioactive glasses are used in many of the above-described cosmetic formulations.

Example 16: Testing zone of inhibition

Liquid Caso agar or Sabouraud's agar was mixed with the appropriate test organism (target: 1005Fu/plate) and pour bowls Petri. After cooling of agar agar beat disc (diameter about 1 cm) and it was filled with approximately 0.5 g of the powder 45S (Bioglass TM) bioactive glass. Agar was kept for 2 hours at 5°and then incubated. After completion of the incubation period (1-5 days), the samples were investigated on the formation and growth of the zone of inhibition.

We used the following test organisms:

- Bacillus subtilis ATCC 6633

- Staphylococcus aureus ATCC 6538

- Pseudomonas aeruginosa ATCC 9027

- Candida Albicans ATCC 10231

- Aspergillus niger ATCC 16404

The results:

The size of zone of inhibition in mm per group samples

Measurement of pH of the nutrient medium without inoculation of microorganisms, in the presence of the sample gave the following results:

The powder glass: pH>= 10

On the agar near the glass powder: pH of 9.5

On agar (periphery): pH 8.5

(the control plate without glass powder): pH 7.5

Example 17: Test the dependence of nibiruan concentration

Liquid Caso agar or Sabouraud's agar. ) and with the appropriate test organism (target: 10 5Fu/plate), and with varying amounts (see table) powder 45S bioactive glass and the resulting mixture was poured into bowls Petri. Agar was kept for 2 hours at 5°and then incubated. After completion of the incubation period (1-5 days) samples were investigated on the formation and growth of the zone of inhibition.

We used the following test organisms:

- Bacillus subtilis ATCC 6633

- Staphylococcus aureus ATCC 6538

- Pseudomonas aeruginosa ATCC 9027

- Candida Albicans ATCC 10231

- Aspergillus niger ATCC 16404

Results: the Counting of microorganisms using different amounts of glass powder

The antimicrobial effect of bioactive glass can be recorded during the testing zone of inhibition, as shown in example 16, and the functional dependence on concentration, as shown in Example 17.

The reduction of microbial growth correlates with increasing pH. The following examples 18 and 19 illustrate the effect of bioactive glass on various microorganisms.

Example 18: a Series of microbiological tests

Run a series of microbiological tests in the presence of individual microorganisms in an aqueous solution of the bioactive glass (clean supernatant), the emulsion of the type oil-in-water and oil emulsions in water, each of which containing the and various concentrations of bioactive glass.

Conditions:

- Suspension of the individual organism

- In the presence of normal salts (in aqueous solution)

- A constant pH value

- Non-sterilized aqueous solution

Accessories:

- Summary tables for load tests of individual microorganisms

- Experienced recipe V99/020/01/11-19 (aqueous supernatant

- Experienced recipe V99/020/02/01a-h (emulsion of the type oil-in-water) (a-h = different concentrations BioGlas/not more than 0,2% VSM12650)

- Experienced recipe V99/020/02/02a-f (emulsion of the type oil-in-water) (a-f = different concentrations BioGlas/not more than 20% VSM1265)

- Experienced recipe V99/020/03/01a-h (emulsion of the type oil-in-water) (a-h = different concentrations BioGlas/not more than 0,2% VSM12650)

- Experienced recipe V99/020/03/02a-a (emulsion of the type oil-in-water) (a-f = different concentrations BioGlas/not more than 20% VSM12650

Test under load MV - 713 (aqueous supernatant)

Test under load MV - 743 (emulsion of the type oil-in-water)

Test under load MV - 773 (emulsion of the type oil-in-water)

- Stability S990029 (V99/020/02/01h)

- Stability S990046 (V99/020/02/02e)

- Stability S990030 (V99/020/03/01h)

- Stability S990029 (V99/020/02/01h)

- Stability S990047 (V99/020/03/02e)

The results:

The aqueous supernatant

Except Aspergillus niger all other testimontials logic test series. At concentrations of bioactive glass in the range of 3-5% growth is not detected even after 6 cycles of load testing. The greatest biological activity of the glass manifests against microorganisms of the species Staphylococcus aureus. Starting from the 4th cycle of the applied load Aspergillus niger no longer shows significant inhibition of growth. Bioactive glass is effective against Aspergillus niger at higher concentrations up to 4-th cycle of the applied load. (Note: the result is not surprising, because unlike other varieties of Aspergillus niger is often a problem with other preservatives).

The emulsion of the type oil-in-water and water in oil

Even at low concentrations of bioactive glass (2%) was observed distinct preservative effect. However, in this case, the behavior of Aspergillus niger is similar to that described above.

Stability

S990029 = emulsion of the type oil-in-water V99/020/02/01h = 0,2% VSM12650

Normal test: -7°/40°C; stable

Extreme test: -14°s/60°s; separation in the third cycle

S990046 = emulsion of the type oil-in-water V99/020/02/02e = 20% VSM12650

Normal test: sustainable

Extreme test: sustainable

S990030 = emulsion of water in oil V99/020/03/01h = 0,2% VSM12650

Normal test: separation in the third cycle/p>

Extreme test: not performed

S990047 = emulsion of water in oil V99/020/03/02e = 20% VSM12650

The emulsion was divided even before the start of the test series.

Example 19: a Series of microbiological tests

Series of microbiological tests of individual microorganisms in the selected emulsion of the type oil-in-water (V99/020/04/03 (G4) = new laboratory sample V99/020/06/01)

Conditions:

The individual suspension of the microorganism

the pH value was changed to values common to cosmetic products (citric acid)

non - sterile

Classification:

table - testing of individual microorganisms under load

- results tables adjust pH and changes of pH values over time

test compounds V99/020/06/01 a-f

test under load MB 991000-1034

Results/conclusions:

Although sterility of microorganisms in the presence of emulsions of the type oil-in-water hard-to-first stroke (control) showed sterility, with the exception of experience with E.coli and Staphylococcus aureus.

The results obtained in Example 19 shows:

1. The pH value of the oil/water base during the test series increases again to values of PE the ed establishment of pH with citric acid. The pH value of the sample not containing bioactive glass, remains unchanged.

2. Microbial growth is clearly inhibited.

3. At elevated concentrations, effectively inhibited the growth of such difficult-to-control microorganisms as Aspergillus niger.

4. High pH values correlate with the degree of inhibition of growth of microorganisms.

Stress testing in the presence of biostable Test series 7A Aspergillus niger/Candida albicans V99/020/06/01 emulsion of the type oil-in-water (Dragil) Non-sterile /pH was not installed

Components of the cleansing action

The present invention also provides new compositions of cleansing preparations, including bioactive glass, and methods of obtaining and applying new, non-toxic cleaning products.

Fine bioactive glass and/or extracts fine-grained bioactive glass may be introduced into the household and industrial cleaning agents. The resulting formulations contain components of the cleansing action with superior cleaning ability and antimicrobial properties and is non-toxic. In addition to the direct antimicrobial effect of bioactive glass, enhancing the cleaning ability of the drug encourages the s pH due to the presence of bioactive glass. In addition, bioactive glass has a high affinity for protein materials such as blood and food, as well as oils and lubricants. Cleaning products containing bioactive glass can be used for effective cleaning and disinfection of surfaces, including surfaces painted walls, wool accessories, furniture, vinyl coating (waxed and unwaxed), vitreous porcelain surfaces, porcelain enamel, the surface of stainless steel, plastic laminate (Formica), plastics, acrylic, glass and chrome surfaces. New cleaning agents can also be used for effective cleaning of textile materials, including, but not limited to, braided wool rugs, various synthetic fibers, as well as garments.

Traditional cleaning component may represent, for example, a compound containing one or more surface-active substances intended for dissolving dirt in the solvent, especially in an aqueous solvent. Surfactants are usually effective in the remediation of oil or lubricants. However, other contaminants, for example, the protein nature of, or containing proteins, such as contamination with blood, other staining substances like coffee or tea, and invisible dirt including contamination by microorganisms, can not be cleared only by using these substances. For this reason, the cleaning formulations usually add decolorizing and/or disinfecting component, resulting in a remaining dirt is removed, at least, so that it is no longer visible. Typically, stains removed in the oxidation treatment after the dissolution of fat and pigment stains.

Typically, oxidation treatment of the impurities is carried out using chlorine-containing chemicals. Chlorine-containing chemical agents usually only removes the dye portion of the dye, and other insoluble substances remain in the main structure of the material. The lack of chlorine as highly reactive chemicals is that he has an aggressive effect on the painted surface materials, such as fabrics, change the color tone or discoloring coloring. In addition, chlorine acts on the material to be treated, especially on the fabric, consequently, after repeated washings destroyed the structure of the material.

Previous attempts to mitigate the oxidizing action of chlorine included the use of peracetic acid. Although peracetic acid has sufficient disinfectant activity, its ability to penetrate into the porous material is insufficient, that is its turn leads to insufficient sterilization of the material. In addition, peracetic acid has oxidizing properties, although to a lesser extent than chlorine. Although the oxidizing effect of nagkalat may not result in discoloration of the material, in most cases, the disinfecting ability of such an agent is insufficient. For example, for this reason you cannot delete the producers of anaerobic spores. In addition, the use of nagkalat damage some materials, for example wool products.

Because of bioactive glass emits ions of CA2+assume that the presence of bioactive glass in an aqueous solution should significantly increase the rigidity of such a solution. Therefore, it was assumed that should increase calcification, resulting in reduced cleaning activity, in connection with which such glass may be unsuitable for use as washing and cleaning agents. Moreover, it was assumed that the abrasive action of the particles of glass can lead to mechanical damage of materials, in particular textile origin, which can lead to corrosion of the fabric. Despite this, the applicants have unexpectedly found that a large number of effective cleaning agents can be obtained from formulations containing bioactive glass. Unexpectedly, it was found that the efficiency of the washing agent does not reduce the clicking in the selection of the ion of an alkali metal and does not seem to increase the hardness of water or calcification. In addition, the new cleaning agents are not correlated and do not damage the cleaned materials, especially textile fabrics that expected from the addition of glass particles.

The bioactive glass can be used as a means of cleaning glass products, because it is “softer”than normal household cleaners and can be used as a mild abrasive. Moreover, soluble minerals released from bioactive glass, strengthen the glass. So, for example, silicon secreted bioactive glass are particularly useful for hardening and protection of glass products, because it prevents cracking. Bioactive glass covers cracks in glass products and creates a protective silicon layer.

Detergent-based bioactive glass has not only biocidal activity against viruses and bacteria, but also has a mild effect on the skin and materials without causing allergic reactions and providing effective cleaning to remove stains such as protein deposits. Non-toxic cleaning agents, with biocidal and praseodymium properties may jointly apply with the solvent containing at least one surfactant.

The cleaning agent is not toxic and has biocidal, Grazer asumini properties when combined with a dissolving agent, containing at least a surface-active agent, and this agent contains particles of bioactive glass, emitting more than 250 µg alkali metal ions per gram of glass particles. Cleaning agent contains particles of bioactive glass, emit, at least 300 μg of alkaline ions per gram of glass particles.

The glass particles preferably have an average size of less than 400 microns. According to another technical solution of the glass particles have an average size less than 100 microns.

The cleaning agent contains as a surfactant component tensed. The cleaning agent contains bioactive glass comprising the following components, present at specified intervals, expressed in mass%: 40-60% SiO2, 10-30% CaO, 0-35% Na2O, 2-8 P2O5, 0-25% CaF2, 0-10%2About3, 0-8% Off2O and 0-5% Mao.

The cleaning agent contains approximately 1-7% of the mass of glass particles to the total weight of cleaning solution. The method of obtaining cleaners provides for the addition of glass particles to at least one surface-active agent, which allocates at least 250 μg of alkali metal ions per gram of glass particles. You can use cleaning products to clean a variety of surfaces and textile materials, in particular for Chi the TCI ware, for cleaning in hospitals, clinics and gastronomic enterprises.

A cleaning agent containing bioactive glass, allocates more than 250 µg alkali metal ions per gram of glass particles. Glass particles in the cleaning agent preferably emit more than 300 μg, in particular more than 500 μg of alkaline ions per gram of glass particles. Even more preferred glass particles that emit more than 1 mg of alkaline ions per gram of glass.

Consider cleanser can be used not only for cleaning and sterilization of surfaces and textiles, but also for cleaning and sterilization of surgical instruments. In addition, cleaning agents containing bioactive glass can be used as a means for washing dishes, particularly in washing machines. New cleansing agents can also be used for disinfection and cleaning of surfaces and materials in the field of sanitation, hospitals and food factories.

Ways to get

The method of producing detergent compositions comprising bioactive glass, is that an effective antimicrobial amount of bioactive glass add or enter in the formulation of cleaning products. The term “effective antimicrobial amount of bioactive glass” refers to rises is th number of bioactive glass with an appropriate particle size, providing effective prevention or elimination of microbial contamination. The number and size of particles of bioactive glass to be included in the formulation of cleaning products may vary depending on the desired duration and degree of purification, and the nature of microbial contamination. The term “effective antimicrobial amount of bioactive glass” can also refer to a sufficient amount of an aqueous extract of bioactive glass, can prevent or destroy microbial contamination. The term “effective antimicrobial amount of bioactive glass” can also refer to a combination of fine-grained bioactive glass and an aqueous extract of the bioactive glass, providing effective prevention or elimination of microbial contamination.

Bioactive glass may be added or included in the formulation of detergents using, for example, such methods and their combinations, as usual mixing with slow, medium, moderate, and even intensive mixing. To achieve a relative homogeneity should provide sufficient mixing. It is preferable that the mixing and stirring was carried out as follows to avoid excessive aeration and to provide a low power shift. Can be used the other way or combination of ways of mixing, dispersion, aggregation and/or emulsification. For example, the mixing can be carried out with the use of devices such as conventional stirrers. Conventional compounding and mixing can be carried out, for example, by using a centrifugal mixing device.

The bioactive glass can be added or enter almost all known formulations of detergents. According to the authors of the invention, the bioactive glass is suitable for inclusion in any of the developed formulations of detergents. Bioactive glass may be a water-based solution melkozernistogo bioactive glass, or a combination of fine-grained bioactive glass and water solution on the basis of the bioactive glass.

The method of obtaining such new components cleaners involves combining a cleaning agent with one or more surface-active substances and bioactive glass. This method may also involve the addition of a solvent. The method includes adding fine-grained bioactive glass and/or an aqueous extract of the bioactive glass. Aqueous solutions of bioactive glass can be dried, for example, by using spray drying or drying under vacuum to obtain an antimicrobial composition. Such compositions can be administered to other antimicrobial solutions is whether cleaning agents to ensure the availability of additional antimicrobial component in solutions cleaning agents.

Household detergents, spot removers and cleaning of fabrics.

The present invention covers a new recipe, with which the bioactive glass is introduced into a variety of different brands of commercial Soaps, stain removers and cleaning tissues, for example in market products under the trademarks Ajax, All, Arm & Hammer, Biz, Bold, Bounce, Carbona, Cheer, Cling Free, Clorox, Dow, Downy, Dreft, Dryel, Era, Fab, Febreze, Fresh Start, Gain, Ivory, K2R, Oxydol, PUREX processes, Rit, Shout, Snuggle, Spray & Wash, Stain Devil, Sun Guddle, Surf, Thoro, Tide, Ultra, Windfresh, Wisk, Woolite, Z Out, as well as in the products of the leading and renowned manufacturers.

Generally, commercial detergents, spot removers and cleaning tissues contain cleaning components (anionic and nonionic surfactants), enzymes, softeners, distributing funds (propylene glycol), buffer agents, water, stabilizers, substances that promote suspendirovanie soil, svetozashchitnye agents, coloring agents and fragrances.

Traditional recipes household Soaps, stain removers and cleaning agents tissues include cleaning components (anionic and nonionic surfactants), sautereau agents, stabilizers, perfume, bleaching and coloring components.

Household detergents, spot removers and tools on what I'm cleaning tissues may also contain one or more of the following substances: sodium hypochlorite, hydrogen peroxide, water softeners (silicates, sodium carbonate), various additives (sodium sulfate), various remedies washing machines, different pococurantism agents, cationogenic surface-active agents and various preservatives.

The present invention provides new formulations of household detergents, stain removers and cleaning tissues, obtained by the introduction of bioactive glass into a combination of any of the above ingredients.

Antimicrobial and pH regulating effects of bioactive glass are particularly useful for household cleaning agents, as they contribute to the destruction of bacteria, odor and increase the pH.

Means for washing dishes

The present invention covers a new recipe, with which the bioactive glass is administered in different varieties such funds for washing dishes, such as the commercial products sold under the trademarks Ajax, All, Cascade, Crystal White, Dawn, Dove, Earth Friendly, Easy Off, Electrosol, Extra Plus, Glass Magic, Ivory, Jet Dry, Joy, Palmolive, Sun Light, as well as the products produced by the leading and reputed manufacturers.

Typically, funds for washing dishes contain a detergent, a compound of an alkali metal to raise pH, surfactant and perfume.

Traditional formulations of detergents for washing dishes contain is of triclosan, water, ammonium Laureth sulphate, laurifolius, dodecylbenzenesulfonate sodium, SD alcohol 3-a, ecological sodium, quaterni-15, lauramid myristamide MEA, perfumes and various coloring agents.

Means for washing dishes can also include one or more of the following substances: chlorine bleach, silicate salts, laurifolius, DMDMH the as Methylchloroisothiazolinone, calcium carbonate, the combination, of anionic surfactants, sodium carbonate, trinacria HEDTA, sodium metabisulfite and various regulators.

The present invention provides new formulations of detergents for washing dishes, resulting from the introduction of bioactive glass into a combination of any of the above ingredients.

Antimicrobial and pH-regulating properties of bioactive glass make it particularly useful for detergents for washing dishes, because they eliminate bacteria and improve cleanability.

Air fresheners and room deodorizers

The present invention covers a new recipe, with which the bioactive glass is introduced into a variety of air fresheners and room deodorizers, such as the products sold under the tradenames Airwick, Arm & Hammer, Clorex, Country Air, Country Rose, Dale, Enoz, Glade, Fresh Lemon, Little Tree, Lysol, Moonlight Bay, One Dop, Pine Closet, Renuzit, Solid Sachet, Wizard, and in the products produced by the leading and reputed manufacturers.

Traditional recipes of air fresheners and room deodorizers include N-alkyl, the chloride dimethylbenzylamine, the chloride octylacrylamide, chloride dioctyladipate-ammonium chloride and didecylammonium.

Air fresheners and room deodorizers may also include one or more of the following substances: saccharinate of alkylenediamine and ethanol.

The present invention provides new formulations air fresheners and room deodorizers, obtained by the introduction of bioactive glass into a combination of any of the above ingredients.

Antimicrobial and pH-regulating properties of bioactive glass make it particularly useful for use in air fresheners and room deodorizers, ensuring the destruction of bacteria and remove odors.

Paper tools for bathroom and kitchen

The present invention covers a new recipe, with which the bioactive glass is introduced into various sorts of fabric funds for the bathroom, care for face, paper towels and napkins, such as the products sold under the trade names of Angel Soft, Bounty, Brawny, Brite-Life, Charmin, Cottonelle, Good & Plenty, Green Forest, Hi Dri, Kleenex, Marcal, Mardi Gras, Md Bath Tissue, Nortern, Puffs, Purely Cotton, Scott, Scotties, So-Dri, Soft'N Gentle, Sparkle, Vanity Fair, Viva, Wash'N Dri, Zee, as well as the products produced by the leading and reputed manufacturers.

Traditional recipes tissue bath tissue products for face, paper towels and napkins include wood pulp, air conditioners for skin care, color additives and fragrances.

The present invention provides new formulations tissue bath tissue products for face, paper towels and napkins, which is obtained by introducing a bioactive glass into a combination of any of the above ingredients.

Cleaning accessories

The present invention covers a new recipe, with which the bioactive glass is introduced into various grades of cotton swab, wipe, hand, washcloths and sponges, such as the products sold under the trade names of Arden, Ecko, Guardsman, Handi Wipes, Johnson & Johnson, Lysol, Mr. Clan, O-Cel-O, Pledge, Q-tips, S.O.S., Scotch Brite, and products izvestnimi leading manufacturers.

The present invention provides new formulations cotton swab, wipe, hand, washcloths and sponges obtained by the introduction of bioactive glass into a combination of any of the above ingredients.

Antimicrobial and pH-regulating properties of bioactive glass are particularly useful for use in cotton is pplicatio, the wipes for hands, washcloths and sponges to destroy bacteria and remove odors. In addition, the abrasive effects of bioactive glass contribute to the removal of dirt and stains.

Cleaning plates

The present invention covers a new recipe, with which the bioactive glass is introduced into various sorts of tools for cleaning plates, such as the products sold under the trade names Dow, Easy Off, Kleen King, as well as the products produced by leading manufacturers.

Usually, cleaning plates include as the active ingredient sodium hydroxide.

The traditional formulation of the means for cleaning plates include water, surfactants, components, removing fat, sodium hydroxide, water conditioners, fragrances, and various coloring agents.

The present invention provides a new formulation of the means for cleaning plates, obtained by the introduction of bioactive glass into a combination of any of the above ingredients.

Antimicrobial properties of bioactive glass are particularly useful tools for cleaning plates to eliminate bacteria and odor.

Cleaning toilets

The present invention covers a new recipe, with which the bioactive glass is introduced into various sorts of means DL is cleaning toilets, for example, the products sold under the trade names of Blu Boy, Bowl Fresh, Clorox, Dale Dow, Lime Away, Lysol, Septonic, Sno Bol, Tiolet Duck, Ty-DOBol, Vanish, Willert Bowl and X-14, as well as the products produced by leading manufacturers.

Usually, cleaning toilets contain as the active ingredient axalingua acid.

The traditional formulation of the means for cleaning toilets contain bromine, chlorine, 1-bromo-3-chloro-5,5-dimethylhydantoin, 1,3-dichloro-5,5-dimethylhydantoin and 1,3-dichloro-5-ethyl-5-methylhydantoin.

Cleaning toilets can also include one or more of the following substances: hydrogen chloride, alkyldimethylbenzylammonium chloride, the chloride octylacrylamide, chloride dodecyldimethylamine and chloride dioctyladipate-ilmoni.

The present invention provides a new formulation of the means for cleaning the toilets due to the introduction of bioactive glass into a combination of any of the above ingredients.

Antimicrobial and pH-regulating properties of bioactive glass are particularly useful for use in means for cleaning toilets to destroy bacteria and remove odors.

Cleaning showers and tubs

The present invention covers a new recipe, with which the bioactive glass is introduced into various sorts of tools for cleaning showers and baths, for example in n the FL, manufactured under the trade names Clean Shower, Comet, Dow, Edfred, Lime-Away, Lysol, Parsons, Pine Sol, Scrub Free, Power Shower, Soft Scrub, Tilex, X-14, as well as the products manufactured by the leading and reputed manufacturers.

Usually cleaning showers and tubs include sodium hypochlorite and/or calcium hypochlorite, detergent and bleach.

Traditional recipes tools for cleaning baths and showers contain chlorides, alkyldimethylbenzylammonium and detergents.

Tools for cleaning baths and showers can also include one or more of the following substances: butyl ether dipropyleneglycol, citric acid, perfume additive, water, calcium carbonate, sodium hypochlorite, chloride of dimethylethylenediamine, glycol ether, surface-active components, components suspendresume soil, cleansing components, different excipients, different coloring components and various means of quality control.

The present invention provides new formulations tools for cleaning baths and showers, which is produced by introduction of bioactive glass into a combination of any of the above ingredients.

Antimicrobial and pH-regulating properties of bioactive glass are particularly useful for use in tools for cleaning baths and showers to destroy bacteria and remove odors.

Means for cisticolas

The present invention covers a new recipe, with which the bioactive glass is introduced into various sorts of tools for cleaning carpets, such as the products sold under the trade names of Arm & Hammer, Carpet Fresh, Folex, Formula 409, Glade, Simply Spot-Less, Spot Shot, Resolve, Shout, Woolite, as well as the products produced by the leading and reputed manufacturers.

Typically, the tools for cleaning carpets include as an active ingredient of sodium bicarbonate and flavoring.

The present invention provides new formulations tools for cleaning carpets, obtained by the introduction of bioactive glass into a combination of any of the above ingredients.

Antimicrobial and pH-regulating properties of bioactive glass are particularly useful for use in means for cleaning carpets to destroy bacteria and remove odors.

Cleaner multi-purpose.

The present invention covers a new recipe, with which the bioactive glass is introduced into various sorts of cleaners, multi-purpose, such as the products sold under the trade names of Amazing White, Biz, Borafeem, Cloralen, Clorox, Ajax, Armstrong, Barkeepers Friend, Behold, Bon Ami, Brasso, Brite, Cameo, Cinch, Clear Calcium Lime Rust Remover, Clorox, Comet, Dow, Easy-Off, Endust, Fantasik, Formula 409, Glass Magic Glass Plus, International Brass &Metal Polish, Johnson, Lysol, Mop & Glo, Mr. Clean, Murphy's, Old English Pine On Pine, Pine Sol, Pledg, Proctor & Gamble, Orange Clean, Orange Glo, Scotts, Simple Green, Soft Scrub, Sparcle, Spic & Span, Tilex, Twinkle, Xtra, Weinmeans, Windex, Wright, Wrights, as well as the products produced by the leading and reputed manufacturers.

Usually cleaning products multipurpose contain hydrochloric sodium and/or hydrochloric calcium, detergent, ammonia and alcohol.

Traditional cleaners multi-purpose contain dehydrate dichloro-S-triazinetrione sodium, cleansing components (calcium carbonate, sodium carbonate, anionic surface-active components), perfume component, various means of quality control and various coloring agents.

Cleaners, multi-purpose can also contain one or more of the following substances: butyl ether dipropyleneglycol, citric acid, bleach, chlorides N-alkyldimethyl ammonium chloride N-alkyldimethylammonium-ammonium, ammonia-D, chloride octylacrylamide, the chloride dioktyldimethylammonium, isopropanol and surfactants.

The present invention provides new formulations cleaners, multi-purpose, obtained by introducing a bioactive glass into a combination of any of the listed ingredients.

Antimicrobial and pH-regulating properties of bioactive glass are particularly useful for use in the Chi is brilliant tools General purpose to destroy bacteria and remove odors. In addition, the abrasive properties of bioactive glass contribute to the removal of dirt and stains.

Jewellery cleaning and metal products.

The present invention covers a new recipe, with which the bioactive glass is introduced into various sorts of tools for cleaning jewelry and metal products, such as the products sold under the trade names of Brasso, International Brass &Metal Polish, Twinkle and Wrights.

The present invention provides new formulations of detergents for cleaning jewelry and metal products obtained by introducing a bioactive glass into a combination of any of the listed ingredients.

Antimicrobial and pH-regulating properties of bioactive glass are particularly useful for use in means for cleaning jewelry and metal products to kill bacteria and remove stains.

Food preservatives, food additives and functional food recipes

Food preservatives

Numerous food items are objects of potential contamination with bacteria such as E. coli. Especially prone to bacterial contamination of beef and chicken meat. Aqueous solutions containing extract bioactive glass have antimicrobial properties. Antibacterial action, partly due to the basic nature the DOI of such solutions (pH above 7, preferably above 9, preferably above 10,5). However, solutions of sodium hydroxide with a relatively high pH value is not as effective in killing bacteria. Accordingly, the solutions, in addition to high pH values, contain additional antimicrobial elements.

The composition of the bioactive glass can be sprayed on the infected surface or be entered in such foods as beef. Since the use of bioactive glass for a variety of purposes approved by the FDA, extract bioactive glass is not dangerous for people. In addition, bioactive glass does not exert any action on the taste and texture of the food product.

It should be noted that in addition to the bioactive glass in food preservatives, food additives and functional food formulations can be administered antibiotics. The addition of antibiotics in food preservatives, food additives and functional food formulations containing bioactive glass, is particularly effective for recipes, which is chewed in the mouth.

Functional foods/food additives

It has been shown in several animal models that soluble silica is an essential element to ensure proper absorption/metabolism of calcium. So, for example, without podderjana the required levels of soluble silicon oxide effect of added calcium can be significantly reduced. Accordingly, the addition of bioactive glass in calcium supplements can improve the absorption of calcium.

In addition, it should be noted increasing the release of calcium supplements that act as neutralizers of acidity. Accordingly, the addition of bioactive glass in the recipe to neutralize the acid can promote the absorption of calcium, and a regulating effect on the pH may also reduce the acidity of the system.

Similarly, other calcium-containing food additives introduced in such foods, such as orange juice, cereals and other foods, may be more useful as a result of increased absorption of calcium under the influence of bioactive glass. In addition, anti-inflammatory properties of bioactive glass make it suitable agent for the treatment of such internal inflammation, as inflammation of the stomach and intestines.

Ways to get

For use in the gastrointestinal tract of particles of bioactive glass may be introduced into an inert carrier and used in the form of such discrete units as capsules, starch wafers, tablets or pellets, each of which contains a given number of particles; in the form of powder or granules; or a suspension or solution in an aqueous or non-aqueous liquid, for example, in VI is e syrup, elixir, emulsion or dose of a liquid medication. Suitable for this purpose, the media can be a starch or sugar, and they may contain lubricating components, fragrances, binding components, and other materials.

Tablets can be obtained by extrusion or molding, optionally, in the presence of one or more accessory ingredients. Molded tablets may be made by molding in a suitable device granular form of the active ingredient, such as a powder or granules, optionally mixed with auxiliary substances, such as fillers, lubricating agents, inert diluents, surface-active or dispersing agents. Molded tablets may be made by molding in a suitable device is a mixture of the powdered active compound and a suitable carrier.

Syrup slurry may be prepared by adding the active compound to a concentrated, aqueous solution of sugar, for example sucrose, to which may be added as auxiliary ingredients. Such auxiliary ingredients may include fragrances, retarder crystallization of sugar or component to increase the solubility of any other ingredient, such as polyhydric alcohol, glycerin or sorbitol.

Ka is of egorie functional foods/food additives

One of the embodiments of the present invention relates to the production of new formulations with which the bioactive glass is introduced into various sorts of numerous functional foods and dietary supplements, including: substances-converters acidity, calcium supplements and nutritional supplements on the basis of silicon oxide.

The acid neutralizers

The present invention covers a new recipe, with which the bioactive glass is administered in different varieties such acid neutralizers, such as the commercial products sold under the trade names Alka-Mints, Alka-Seltzer, Amitone, Axid, Brite-Life, Bromo Seltzer, Di-Gel, Gas-X, Gaviscon, Gelusil, Good Sense, Imodium, Kaopectate, Lactaid, Maalox, Mag-Ox, Mylanta, Pepcid AC Pepto-Bismol, Phazyme, Phillips, Prelief, Riopan, Rolaids, Sal De Picot, Tagamet, Tempo, Titralac, Tums, Zantac, and products produced by the leading and reputed manufacturers.

Traditional formulations of acid neutralizers contain aspirin, sodium bicarbonate, citric acid, sodium citrate, atsetilsalitsilata sodium, aspartame, odorants and phenylalanine.

Components, neutralizing acidity, can also contain one or more of the following substances: calcium carbonate, magnesium stearate, mineral oil, sodium hexametaphosphate, sodium, starch, stearic acid, sucrose, talc, aluminum hydroxide, magnesium carbonate, alginic acid, calcium stearate, Isparta is, sodium-croscarmellose, silicon dioxide, various artificial and natural flavors, and various coloring components.

The present invention provides for new formulations of products to reduce acidity, by introducing a bioactive glass into a combination of any of the above ingredients.

Anti-inflammatory and antimicrobial properties of bioactive glass are particularly useful for use in products to reduce the acidity to reduce inflammation and kill bacteria.

Calcium supplements

The present invention includes new recipes, by which the bioactive glass is introduced into various grades of calcium supplements and foods with additives, including: diet supplements pills and gum, acid neutralizers, means to relieve pain, toothpaste, cereals, snacks, drinks and various food seasonings and sauces, such as the products sold under the trade names Alke-Mints, Amitone, Basic Nutrition, Bayer, Biotene, Black Radiance, Brite-Life, Calcet, Cal-Max, Caltrate, Cantrum Kids, Citratel, Dical-D, Di-Gel, drugstore.com, Enamelon, Ensure, Equalactin, Estroven, FiberCon, Flintstones, Flirical, FosFree, Futurebiotics, Gas-X, GNC, Good sense, Healthy Woman, Konsyl, Maalox, Mylanta, Natrol, Naturalife, Natural Wealth, Naturally Scientific, Nature Made, Nature's Bounty, Nature's Reward, Nature's Way, Neo-Calglucon, Naphro-CaIci, Nutrition Now, One-A-Day, Orly, Os-Cal, PharmAssure, PhenSafe, Phillps, Posture, Prelief, Provate, R & C R&D, Rainbow Light, Revlon, Roberts, Rolaids, Sciff, Similac, Solgar, Stuart Prenatal, Sundown, Surfak, Thompson, Titralac, Tums, Twinlab, Viactiv, VitaFresh, as well as the products produced by the leading and reputed manufacturers.

Traditional formulations of calcium supplements and products thereof include calcium carbonate, sulfosuccinate dicitrate, the solid residue hydrogenation of grain, magnesium stearate, polyethylene glycol, sorbitol, sugar, various natural and artificial fragrances, and various coloring components.

Calcium supplements and products thereof can also include one or more of the following substance: adipic acid, silicon dioxide, sodium pyrophosphate, starch, talc, aspartame, lures, maltodextrin, cellulose, mineral oil, crosspovidone, hypromellose, vegetable glycerides, Arabian gum, titanium dioxide, Polysorbate 80, sodium lauryl sulfate, and stearic acid.

The present invention provides new formulations of calcium supplements and products thereof, which are obtained by the introduction of bioactive glass into a combination of any of the above ingredients.

Foods with added silicon dioxide

The present invention includes new recipes, by which bioactive glass injected into different the e varieties of food additives, containing silicon dioxide and the products of such additives include: dietary supplements in the form of pills and chewing gums, toothpastes, shampoos, preparations for body wash and assorted condiments and sauces, such as the products sold under the trademarks Body Essential, Crest, Futurebiotics, GNC, Natrol, Nature's Herbs, Nature's Way, Peter Thomas Roth, as well as the products produced by the leading and reputed manufacturers.

Traditional formulations of additives on the basis of silica and products containing such additives include stearic acid, secondary acidic calcium phosphate, cellulose and magnesium stearate.

Supplements based on silica and products containing such additives can also include one or more of the following substances: rice powder, silicon dioxide, gelatin and water.

The present invention provides new formulations of additives on the basis of silica and products containing such additives, which are obtained by the introduction of bioactive glass into a combination of one or more of the above ingredients.

On the other hand, the very bioactive glass can be considered as a Supplement containing silicon dioxide, or it may replace silicon dioxide in existing formulations of silicon additives.

The inventors have found that bioactive glass provide unexpected R. the results in comparison with standard dietary supplements on the basis of silicon dioxide. It was found that bioactive glass secrete soluble silica into the surrounding physiological environment such beneficial ways that were not previously taken into account. In addition, bioactive glass have unusually high physical surface, which contains silanol groups, which are active in many ways similar to the activity of silicon dioxide. It should be noted that it is written especially true for Sol-gel derived glasses.

Applicants have found that secreted soluble silicon dioxide and the available silanol groups provide an effective mechanism for the sequestration and removal of metal ions from the body. Particles of glass, which may be of micron dimensions, isolate or bind metal ions, which are collected by the relevant authorities (e.g., kidney and intestine and excreted. Thus, the bioactive glass can be used to reduce or minimize the toxic effects of many metal ions.

Bioactive glass are particularly useful to reduce or minimize the toxic effects of aluminum. In addition to the above-discussed ability to isolate or binding, bioactive glass allocate additional amounts of calcium and phosphate, which tend to bind aluminum. Associated still is, the aluminum has low toxicity and does not violate physiological processes.

In accordance with these nutritional supplements containing bioactive glass may be useful agents for the treatment or prevention of many harmful and painful processes and conditions associated with, for example, with the inclusion of aluminum, such as osteoporosis, osteodystrophy and other conditions under which the desired stimulation osteoblastic activity.

In addition, such supplements linking aluminum, may be useful for the prevention, slowing or reversal of the symptoms of Alzheimer's disease, various forms of encephalopathy and various forms of dysfunction of the myocardium.

In addition to the binding of aluminum, the bioactive glass is able to bind ions of other metals, such as lead, cadmium, zinc and iron. Accordingly, in this case, can be prevented, slowed or reversereverse harmful or toxic effects of these and other metal ions.

In addition to the above products, bioactive glass may be added or introduced in the following household products: dust filters, paint for walls/Wallpaper, toilet seats, mildew removers, ceramic/ceramic laminates for the bathroom, water filters, fillers mattresses, cleaning products for sun decks and loungers, free brushes, mats for Pets (for example, products manufactured under the trade and the names of the Litter Clean, Tidy Cat, Arm & Hammer, Classy Cat, Everfresh, Fresh Step, Jonny, Sani-Scoop and Scoop Away) and cutting tables, which gives the listed products high resistance against microbial infection and increases the pH value.

In addition, the present invention provides a new products intended for animal care and veterinary use. Bioactive glass may also be added or entered by, for example, in the following tools animal care/veterinary drugs, to provide such means high resistance to microbial infection and increased PH: sand in cages for keeping birds, litter for kittens, protivobloshinye powder and dry shampoo for animals.

In addition, the bioactive glass may be added or introduced in the following products: fungicides/pesticides for agriculture, means for removal of marine pollution, coatings for glass products and cleaners containers for food and beverages, concrete, ceramics and tiles to give these products a high resistance to microbial contamination and increase their pH.

1. Cosmetic composition comprising bioactive glass and practically anhydrous cosmetic formulation, in which the bioactive glass contains SiO2, CaO, P2About5optional Na2O.

2. HDMI is tion according to claim 1, in which the use of bioactive glass obtained by melting.

3. The composition according to claim 1, in which the use of Sol-gel derived bioactive glass.

4. The composition according to claim 1, in which the bioactive glass is an aqueous extract.

5. The composition according to claim 1, in which practically anhydrous cosmetic formulation selected from the group consisting of lipstick, lip balm, eyeshadow, cream base for skin care around the eyes, Foundation and face powder.

6. The composition according to claim 1, in which the cosmetic formulation contains as the main components of the oil, beeswax, vitamin E and paraben.

7. The composition according to claim 6, in which the cosmetic formulation contains as main components lipstick or lip gloss.

8. The composition according to claim 1, in which the cosmetic formulation contains as a main component composition for brightening on the basis of str.

9. The composition of claim 8 in which the composition for brightening on the basis of str is up to about 95% of the cosmetic compositions.

10. The composition according to claim 1, in which the cosmetic formulation comprises glycerin.

11. The composition according to claim 1, in which the cosmetic formulation contains the composition for brightening based on str, talc and Sol-gel derived bioactive glass.

12. The composition according to claim 1, containing lacquer KRA is Italy Red 7 CA Lake, Red 6 BA Lake, Red 33 AI lake, castor oil, Carnauba wax, candelilla wax, ozokerite wax, oil, str, vitamin E, methyl paraben, propyl paraben and bioactive glass 45s.

13. The composition according to claim 1, containing lacquer dyes Red 7 CA Lake, Red 6 Ba Lake, Red 33 AI Lake, castor oil, Carnauba wax, candelilla wax, ozokerite wax, microcrystalline wax, oil, str, vitamin E, methyl paraben, propyl paraben, bioactive glass 45s and bioactive glass 58s.

14. The composition according to claim 1, containing gloss oil-based str and bioactive glass, which has an average particle size less than 5 microns.

15. The composition according to claim 1, containing glycerol, Pemulen® TR-2 and bioactive glass, which has an average particle size less than 5 microns.

16. The composition according to claim 1, containing gloss oil-based str, brown iron oxide, titanium dioxide, talc, and Sol-gel derived bioactive glass.

17. The composition according to claim 1, containing oil str, Lurajel® MS, pigment and bioactive glass.

18. The composition according to claim 1, containing Polawax®, mineral oil, glycerin, juguar C14-S, citric acid, feeback, coloring component, the odorant and bioactive glass.

19. A method of obtaining a cosmetic composition, which consists in mixing the bioactive glass with virtually anhydrous cosmetic composition.

20. The method according to claim 19, which uses the t bioactive glass, obtained by melting.

21. The method according to claim 19, in which the use of Sol-gel derived bioactive glass.

22. The method according to claim 19, in which the bioactive glass is an aqueous extract.

23. The method according to claim 19, in which practically anhydrous cosmetic composition selected from the group consisting of lipstick, lip balm, eyeshadow, cream base for skin care around the eyes, Foundation and face powder.

24. The method according to claim 19, in which the cosmetic composition contains oil, beeswax, vitamin E and paraben.

25. The method according to claim 19, in which the cosmetic composition comprises a composition for brightening oil-based str.

26. The method according to claim 19, in which the cosmetic composition comprises glycerin.

27. The method according to claim 19, in which the cosmetic composition comprises a composition for brightening based on str, talc and Sol-gel derived bioactive glass.

28. The method according to claim 19, in which the cosmetic formulation contains lacquer dyes Red 7 CA Lake, Red 6 BA Lake, Red 33 AI Lake, castor oil, Carnauba wax, candelilla wax, ozokerite wax, microcrystalline wax, oil, str, vitamin E, methyl paraben, propyl paraben and bioactive glass 45s.

29. The method according to claim 19, in which the cosmetic formulation contains lacquer dyes Red 7 CA Lake, Red 6 Ba Lake, Red 33 AI Lake, castor oil, carnaubic the th wax, candelilla wax, ozokerite wax, microcrystalline wax, oil, str, vitamin E, methyl paraben, propyl paraben, bioactive glass 45s and bioactive glass 58s.

30. The method according to claim 19, in which the cosmetic formulation contains the composition for lip gloss based on str and bioactive glass, which has an average particle size less than 5 microns.

31. The method according to claim 19, in which the cosmetic formulation contains glycerin, Pemulen® TR-2 and bioactive glass particles which have an average size of less than about 5 microns.

32. The method according to claim 19, in which the cosmetic formulation contains lip gloss oil-based str, brown iron oxide, titanium dioxide, talc and the Sol-gel derived bioactive glass.

33. The method according to paragraph 24, in which the cosmetic composition contains a lipstick or lip balm.

34. The method according to p, in which the composition is based on str contains up to about 95% of cosmetic compositions.

35. Cosmetic composition comprising bioactive glass, cosmetic formulation and the buffer in which the bioactive glass contains SiO2, CaO, R2About5and, optionally, Na2O.

36. The composition according to p containing mineral oil, wax, glycerin, water, and Sol-gel derived bioactive glass.

37. The composition according to p containing oil-based str, water, Tio2and propylenglycol the ü.

38. The composition according to p, in which the use of bioactive glass obtained by melting.

39. The composition according to p, which is used as a Sol-gel derived bioactive glass.

40. The composition according to p, in which the bioactive glass is an aqueous extract.

41. The composition according to p, in which the buffer is citric acid.

42. The composition according to p, in which the cosmetic formulation is selected from the group consisting of lipstick, lip balm, eyeshadow, cream base for skin care around the eyes, Foundation and face powder.

43. Composition. p, which contains mineral oil, wax, glycerin, water, and Sol-gel derived bioactive glass.

44. The composition according to p containing mineral oil, Polwax, glycerin, deionized water, juguar C-14s, feeback, perfume, powder monohydrate citric acid Sol-gel derived bioactive glass.

45. The composition according to p in which cosmetic formulation contains concealer for the face.

46. The composition according to p, which contains crodafos CES, volpo 10, volpo 3, oil str, cyclomethicone D5, deionized water, NaOH, Tio2, red iron oxide, a mixture of black and brown iron oxides in the ratio of 50:50, propylene glycol, juguar 13S, germaben II and bioactive glass 45s.

47. The composition according to p containing the AOC is Athos CES, volpo 10, volpo 3, oil str, cyclomethicone D5, deionized water, NaOH, Tio2, red iron oxide, a mixture of black and brown iron oxides in the ratio of 50:50, propylene glycol, juguar 13s, germaben II and bioactive glass 58s.

48. A method of obtaining a cosmetic composition, which is mixed bioactive glass, cosmetic formulation and buffer, and bioactive glass contains SiO2, CaO, P2O5and optional Na2O.

49. The method according to p, in which the cosmetic composition comprises mineral oil, wax, glycerin, water, and Sol-gel derived bioactive glass.

50. The method according to p in which cosmetic formulation contains oil str, water, Tio2and propylene glycol.

51. The method according to p, in which the use of bioactive glass obtained by melting.

52. The method according to p to use Sol-gel derived bioactive glass.

53. The method according to p, in which the bioactive glass is an aqueous extract.

54. The method according to p, in which the buffer is citric acid.

55. The method according to p, in which the cosmetic formulation is selected from the group consisting of lipstick, lip balm, eyeshadow, cream base for skin care around the eyes, Foundation and face powder.

56. The method according to p in which cosmetic formulation sod is RIT mineral oil, wax, water, and Sol-gel derived bioactive glass.

57. The method according to p, in which the cosmetic composition comprises mineral oil, Polwax, glycerin, deionized water, juguar C-14s, feeback, perfume, powder monohydrate citric acid Sol-gel derived bioactive glass.

58. The method according to p in which cosmetic formulation contains concealer for the face.

59. The method according to p, in which the cosmetic composition contains crodafos CES, volpo 10, volpo 3, oil str, cyclomethicone D5, deionized water, NaOH, Tio2, red iron oxide, a mixture of black and brown iron oxides in the ratio of 50:50, propylene glycol, juguar 13s, germaben II and bioactive glass 45 S.

60. The method according to p, in which the composition contains crodafos CES, volpo 10, volpo 3, oil str, cyclomethicone D5, deionized water, NaOH, TiO2the mixture of black and brown iron oxides in the ratio of 50:50, propylene glycol. juguar 13s, germaben II and bioactive glass 58s.

61. Stable cosmetic composition, does not cause irritation, containing bioactive glass and cosmetic formulation having a pH value in the range of 8-12, in which the bioactive glass contains SiO2, CaO, R2O5and, optionally, Na2O.

62. Way to obtain is not causing irritation stable cosmetic compositions, the conclusion is audica a mixture of bioactive glass and cosmetic formulations, in which the pH of the composition is set in the range of 8-12 and bioactive glass contains SiO2, CaO, R2O5and, optionally, Na2O.

63. Cosmetic composition, does not cause irritation, containing bioactive glass and cosmetic formulation, which contains at least one connection, not irritant effect on the skin when it is a separate application, in which the bioactive glass contains SiO2, CaO, R2O5and, optionally, Na2O.

64. The way to reduce and/or prevent irritation of the skin, consisting in applying to the skin a cosmetic composition, as claimed in p.

65. Cosmetic composition intended for odor reduction, containing bioactive glass and cosmetic formulation, in which the bioactive glass contains SiO2, CaO, R2O5and, optionally, Na2O.

66. Method of reducing odor, which consists in applying to the source of the smell cosmetic formulations claimed in p.

67. The composition is designed to filter UV light containing bioactive glass and cosmetic formulation, in which the bioactive glass contains SiO2, CaO, R2O5and, optionally, Na2O.

68. Cosmetic composition according p, which is used as a Sol-gel derived bioactive glass.

69. Kosmet is ical composition on p, in which cosmetic formulation contains at least one basis sunscreen gel.

70. Cosmetic composition according p in which cosmetic formulation contains gloss oil-based str and at least one basis sunscreen gel.

71. Cosmetic composition according p in which cosmetic formulation contains gloss oil-based str, octylmethoxycinnamate, besomeone-3 and bioactive glass.

72. The composition according to p containing gloss oil-based str, octylmethoxycinnamate, benzophenone-3 and Sol-gel derived bioactive glass.

73. The way to protect skin from UV light, which consists in applying to the exposed skin cosmetic formulations according p.

74. The way to protect skin from UV light, which consists in applying to the exposed skin cosmetic formulations according p.

75. Cosmetic composition according p, in which the gloss oil-based str contains up to about 95% of cosmetic compositions.

76. The way to protect skin from UV light, which consists in applying to the exposed skin cosmetic formulation according to item 70.

77. The way to protect skin from UV light, which consists in applying to the exposed skin cosmetic formulations according p.

78. Cosmetic composition, absorbent containing bioactive glass and cosmetic re is aturu, in which bioactive glass contains SiO2, CaO, R2O5not necessarily, Na2O.

79. Cosmetic composition according p, in which the applied Sol-gel derived bioactive glass.

80. The method of absorption of moisture, which consists in applying to the source of moisture cosmetic formulations according p.

81. Composition for personal hygiene, containing bioactive glass and cosmetic formulation, in which the bioactive glass contains SiO2, CaO, R2O5and, optionally, Na2O.

82. The composition according to p, in which the use of bioactive glass obtained by melting.

83. The composition according to p, which is used as a Sol-gel derived bioactive glass.

84. The composition according to p, in which the bioactive glass is an aqueous extract.

85. The composition according to p, in which the means of personal hygiene are selected from the group consisting of wipes, care for adults suffering from incontinence, feminine hygiene products, shampoos, hair care products, deodorants, foot care, care for children, sunscreen, body wash, skin care and nutritional supplements.

86. The composition according to p containing pencil deodorant and bioactive glass in which the amount of bioactive glass is 4-10% of the total weight of the HDMI is tion.

87. The composition according to p containing cream deodorant and bioactive glass in which the amount of the bioactive glass comprises 30-60% by weight of the composition.

88. A method of obtaining a composition for personal hygiene, which consists of the combined use of bioactive glass and personal care products in which the bioactive glass contains SiO2, CaO, R2O5not necessarily, Na2O.

89. The method according to p, in which the use of bioactive glass obtained by melting.

90. The method according to p to use Sol-gel derived bioactive glass.

91. The method according to p, in which the bioactive glass is an aqueous extract.

92. The method according to p, in which the means of personal hygiene are selected from the group consisting of wipes, care for adults suffering from incontinence, feminine hygiene products, shampoos, hair care products, deodorants, foot care, care for children, sunscreen, body wash, skin care and nutritional supplements.

93. Stable composition, does not cause irritation, for personal hygiene, containing bioactive glass and means of personal hygiene, having a pH value in the range of 8-12, in which the bioactive glass contains SiO2, CaO, R2O5and, optionally, Na2O.

94. The way the floor is the treatment does not cause irritation stable cosmetic composition for personal hygiene, consisting in the use of bioactive glass and personal care products having a pH in the range of 8-12, in which the bioactive glass contains SiO2, CaO, R2O5and, optionally, Na2O.

95. Composition for personal hygiene, weakening the smell, containing bioactive glass and means of personal hygiene, having pH of the composition in the range of 8 to 12, in which the bioactive glass contains SiO2, CaO, R2O5and, optionally, Na2O.

96. Method of reducing odor, which consists in applying to the source of the odor composition for personal hygiene, as claimed in p.

97. Composition for personal hygiene, with the ability to filter UV light containing bioactive glass and means of personal hygiene, in which the bioactive glass contains SiO2, CaO, R2O5and, optionally, Na2O.

98. Composition for personal hygiene on p, which is used as a Sol-gel derived bioactive glass.

99. Composition for personal hygiene on p in which cosmetic formulation contains at least one sunscreen gel.

100. Composition for personal hygiene on p in which cosmetic formulation contains gloss oil-based str and at least one sunscreen gel.

101. Composition for personal hygiene in item 100, in which the gloss oil-based str contains what about the 95% of the cosmetic formulation.

102. The composition according to p containing gloss oil-based str, octylmethoxycinnamate, benzophenone-3 and bioactive glass.

103. The composition according to p containing gloss oil-based str, octylmethoxycinnamate, benzophenone-3 and Sol-gel derived bioactive glass.

104. A means of personal hygiene on the basis of the composition of p that contains a sun filter.

105. The way to protect skin from UV light, which consists in applying to the exposed skin personal care products based on the composition of p.

106. The way to protect skin from UV light, which consists in applying on the irradiated skin personal care products based on the composition of p.

107. The way to protect skin from UV light, which consists in applying to the exposed skin personal care products based on the composition of item 100.

108. Remedy skin from UV light, which consists in applying to the exposed skin means on the basis of the composition of p.

109. Absorbent composition for personal hygiene, containing bioactive glass and means of personal hygiene, in which the bioactive glass contains SiO2, CaO, R2O5and, optionally, Na2O.

110. Absorbent composition for personal hygiene on p, which is used as a Sol-gel derived bioactive glass.

111. The way my absorption is Oia moisture, which consists in applying to the source of the moisture composition for personal hygiene on p.

112. Composition for hair care products containing bioactive glass and means for care of hair, in which the bioactive glass contains SiO2, CaO, R2O5and, optionally, Na2O.

113. The composition according to p, in which the means for care of hair is a shampoo.

114. The composition according to p containing standapol ES, resultin C-50, foamed With deionized water, juguar C-14S, feeback, perfume, powder monohydrate citric acid and bioactive glass.

115. The composition according to p containing standapol ES, resultin C-50, foamed With deionized water, feeback, powder monohydrate citric acid and bioactive glass.

116. The composition according to p containing steol CS-230, resultin C-50, foamed, deionized water, fenobam, powder monohydrate citric acid and bioactive glass.

117. The composition according to p containing steol CS-230, resultin C-50, foamed With deionized water, feeback and bioactive glass.

118. Composition for hair care on p in which shampoo contains citric acid.

119. Composition for hair care on p, in which the bioactive glass has an average particle size less than 5 microns.

120. The composition according to p, in which the bioactive glass contains up to about 10%by weight of the composition.

121. The composition according to p, in which the bioactive glass contains up to about 7% by weight of the composition.

122. The composition according to p, in which the bioactive glass has an average particle size less than 5 microns.

123. The composition according to p, in which the bioactive glass has an average particle size less than 5 microns.

124. Food composition comprising bioactive glass and nutritional Supplement, in which the bioactive glass contains SiO2, CaO, R2O5and, optionally, Na2O.

125. The composition according to p, in which the use of bioactive glass obtained by melting.

126. The composition according to p, which is used as a Sol-gel derived biactive glass.

127. The composition according to p, in which the bioactive glass is an aqueous extract.

128. The composition according to p in which the food additive is selected from the group consisting of neutralizers acidity, calcium supplements and additives on the basis of silicon dioxide.

129. The composition according to p, optionally containing iodine.

130. A method of obtaining a composition for dietary supplements containing bioactive glass and food additive, in which the bioactive glass contains SiO2, CaO, R2O5not necessarily, Na2O.

131. The method according to p, in which the use of bioactive glass obtained by melting.

132. The method according to p to use Sol-gel proizvodi the e bioactive glass.

133. The method according to p, in which the bioactive glass is an aqueous extract.

134. The method according to item 13 0, in which the food additive is selected from the group consisting of neutralizers acidity, calcium supplements and additives on the basis of silicon dioxide.

 

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