The method of normalization of the biological functions of living tissues and device for electromagnetic effects on living tissue

IPC classes for russian patent The method of normalization of the biological functions of living tissues and device for electromagnetic effects on living tissue (RU 2160130):

A61N2/02 - using magnetic fields produced by coils, including single turn loops or electromagnets (A61N0002120000 takes precedence);;

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(57) Abstract:

The invention relates to the field of medicine and medical technology and relates to methods and means of therapeutic effects of electromagnetic fields on living tissue. The method has a stimulating influence of electromagnetic fields on the metabolic processes in body tissues, leading to positive changes of the functional state of regulatory systems. Biomechanical, bioelectrical, and bio-processes in the vascular system for non-contact electromagnetic effects on the elements of the vascular system with a high degree of selectivity control the tone of the vascular wall. The method and apparatus can reduce the time of treatment, post-operative and other forms of rehabilitation through deep contactless interaction of biological tissues of the patient, provide sensory fields of the body at the information level, with low-frequency electromagnetic fields that are created by the proposed device with a special beadequate parameters for dynamic (i.e. time and form parameters), amplitude, and spatial and geometric properties. The proposed device consists of spout on electromagnetic inductor, converts electrical signals into electromagnetic field with the specified required properties defined in the fundamental theoretical research and experiments. 3 S. and 12 C.p. f-crystals, 2 Il.

The invention relates to the field of medicine and medical technology and relates to methods and means of therapeutic effects of electromagnetic fields on living tissue.

Electromagnetic fields are a major factor in the majority of physiotherapeutic procedures, aimed at normalizing the functions of organs and tissues, broken for one reason or another, and the most widely used in medical practice. There are dozens of variants of the methods and schemes of therapeutic effects of electromagnetic fields on the human body, designed to restore disturbed functions of individual organs.

Known, for example, a method of treatment of vascular diseases of the brain atherosclerotic nature, consisting in the impact on the area of projection of the lesion in the brain's electromagnetic field with a frequency of 50 Hz and tension 90-250 E. the Observed improvement in hemodynamics due to the increase in linear velocity of blood flow, blood vessels Gal, A 61 N 2/04, 1982].

A method for treatment of postoperative liver failure by preventing stagnation of blood in the portal region of the spleen, providing the impact on the hepatic artery of the electromagnetic field in the systolic phase of the cardiac frequency of 80-100 Hz and diastolic - 800-1000 Hz. Currents with a frequency of 80-100 Hz affect the sympathetic nervous system, cause the relaxation of smooth muscles and reducing pressure in the proper hepatic artery. Currents with a frequency of 800-1000 Hz affect the parasympathetic nervous system, causing a sharp increase in the tone of smooth muscles and increasing the pressure in the proper hepatic artery [Ed.mon. The USSR 1147408, And 61 N 1/18, 1985].

In the case of thrombosis of the blood vessels can affect this region of the electromagnetic fields in the radio frequency range (200-500 kHz) when the power of the field is equal to 0.1-10 W [international application WO 97/10875, And 61 N 2/00,1997].

Improving kroveobraschenie organs and tissues, which helps to reduce pain syndromes of different localization can be achieved by placing on the patient's body belt, containing a series of sources of alternating electromagnetic fields [European what I regional blood flow in the area of pathology to carry out consistent electromagnetic fields with different amplitude, frequency and temporal characteristics, namely: originally diseased tissue was recommended to influence the field with induction of 2.5 to 1.2 MT and a frequency of 0.8-2.5 Hz for 15-20 minutes, then a field with induction 3,0-4,0 MT and a frequency of 2.2 to 3.0 Hz for 25-35 minutes. In this mode of exposure was achieved optimal removal of spasm of the blood vessels and normalizing the tone of the walls of the veins. The shape of the pulse within these frequency and amplitude parameters corresponds to a symmetric exponential current pulse in the system of solenoids with respect to the fronts of the rise and fall of current pulses 5010% [RF Patent 2019209, And 61 N 2/04, 1994].

In dentistry, for the treatment of soft tissue prosthetic bed, on the skin in the area of the projection on it of the affected area of tissue affected by an electromagnetic field with a pulse frequency of 3 to 30 Hz with a modulation frequency of 0.3-0.8 Hz and with a wide spectrum of harmonic components 500 Hz - 1 kHz, and then increase the pulse frequency electromagnetic fields up to 80-120 Hz and continuing impact.

The selection of exposure parameters is due to the fact that the pulse repetition rate in the range from 3 to 30 Hz adequate living organism, ø the resources to regulate the metabolic processes in living tissues, the modulation frequency in the range of 0.3 to 0.8 Hz allows the formation of breaks to ensure the patient is comfortable even when the pulse frequency above 30 Hz.

For the individualization of treatment on pre-control plot facial skin the particular patient in the exit area of the front branch of the trigeminal nerve define the characteristics of the natural electromagnetic field of the fabric, due to its activity, and subsequent exposure to form an electromagnetic field with the appropriate parameters [RF Patent 2119360, And 61 N 2/00, 1998].

To accelerate healing of bone fractures and elimination of circulatory disorders recommended to affect living tissue time-varying electromagnetic field generated by a unipolar rectangular pulses with a pulse frequency of 0.1-100 Hz and with an amplitude of 0.1 to 15 volts. In use the device is provided by the presence of a bias network which prevents pulses of opposite polarity in the fall of magnetic flux caused by falling pulse [European application 0181053, And 61 N 1/42, 1986].

The described method and apparatus for non-invasive local vozdeistviyah coils, creating in this field the electromagnetic field. This method involves the use of non-invasive ultrasonic echo-Doppler monitoring of the propagation of the pulse wave through the selected region, and calculating changes in the velocity of propagation of the wave as a criterion of the effectiveness of exposure to electromagnetic fields. The method is capable of selectively change the dynamics of blood circulation at least in the area of impact. The shape of the pulse is asymmetric and contains the pulsating component of the signal. Quantitative parameters of the applied electromagnetic fields are not [European patent 0145173, And 61 N 1/42, 1984].

Patented device for influencing the biological functions of living tissues pulsed electromagnetic field designed for the transport of ions from the electrolytic body fluids into surrounding blood vessels and membranes and through them. The device provides exposure to electromagnetic fields, with parameters chosen so that the energy induced them in the electrolytic liquid, exceeded thermal energy and was within the amplitude window, characteristic of cells, and the primary current is by exponential dependence, with the subsequent interval, with a shorter duration; the fundamental frequency of the primary current pulse intervals between the main pulses is 100-1000 Hz; the amplitude of the main sequence of pulses modulated by a frequency of 0.5-35 Hz; a modulated sequence of the main pulse is transmitted in the form of a series of pulses within 0.3-1.0, followed by a pause during 5,0 C.

To optimize the exposure options field, preferably with the aid of biofeedback. In particular, it is possible to measure blood pressure and to regulate the impact on the achievement of the optimal value. The device includes a driver signal comprising a generator of low-frequency current pulses, the output of which is connected to the transmitting antenna for exposure on the treated area of the body, and is characterized by the ability to ensure the creation of electromagnetic fields with the above characteristics [RF Patent 2093213, And 61 N 2/04, 1997].

The known method and the corresponding device designed to stimulate Central and peripheral nervous system for therapeutic purposes, providing the impact is, izdavaemyh individual coils and electrodes placed in the impact zone [European application 0709115, And 61 N 2/00, 1996].

The proposed device for the treatment of diseases or conditions associated with redness of the tissues, mainly the limbs, which provides the ability to overlay on the area of influence of the magnetic field across the main direction of the blood vessels and the electric field across the magnetic field direction, resulting electrically charged particles of the blood, such as ions, receive a spiral rotational motion and blood flow in the tissue increases [international application WO 82/01135 And 61 N 1/42, 1982].

The described apparatus and method for the treatment of viral and genetic diseases, based on the impact on the affected biological material, for example a gene or a virus, electromagnetic fields and energy density and pulse repetition rate, which are determined as a function of the mass of the object exposure. The energy of the field is chosen equal to the energy of gravity affected the biological material, in order to achieve resonant mode. The procedure is carried out in aqueous medium, in which is immersed solenoid, inside which creates a magnetic the method and the apparatus, the principle of action which involves application of static magnetic fields with intensity 1-30 MT and low-frequency electromagnetic fields with a frequency of 1-1000 Hz, which are control fields [European application 0966988, And 61 N 2/02, 1999].

Described, numerous variations of the combined therapeutic effects of electromagnetic fields and other physical factors used in medicine.

The patented method of treatment of diseases associated with the appearance in the body of abnormal cells, in particular tumor, which is that in the blood of the body is injected compounds capable of generating chemical energy, in particular oxyhemoglobin iron, which can penetrate infected cells; blood is saturated with oxygen by hyperbaric oxygenation, which increases the rate of oxidative processes and metabolism in infected cells and the formation of interleukins and other activators which destroy cells; effect on infected cells by electromagnetic fields, the frequency of which is equal to one of the frequency of the electromagnetic absorption spectrum that is closest to the frequency calculated for the affected cells, and most removed from the healthy frequency is tion of the body is that area is imminent impact on the patient's body lay two electrodes made of materials with different electrochemical potentials, creating a biogalvanic element. The electrodes of this biogalvanic element connected to a power bus of the generator of electrical oscillations, an output signal which is converted into acoustic vibrations of the same frequency and form, submitting it on acoustic transducers placed in the zone of overlap of the electrodes.

As a result of biogalvanic item on the electrodes there is a potential difference, which is converted by a generator into alternating voltage is sinusoidal or pulsed form of the audio frequency range 1-10 kHz, and then the transducer in acoustic oscillations of the same frequency and shape. As the internal resistance of the tissue of the biological environment of the organism is large, then a significant part of the variable component of the oscillation generator is allocated to the electrodes biogalvanic element. The incidence of both mechanical and electrical oscillations generated in the area of impact is determined by the frequency of the oscillator circuit.

This method implements the energy generated by osdate, because they are established and regulated by the body type of feedback.

The device for implementing this method comprises a generator of electrical oscillations of audible frequency and connected with its output emitter of sound vibrations that contains a mobile element, such as a membrane, and at least one galanopoulou consisting of positive and negative electrodes made of electrically conductive materials with different electrochemical potentials, and the positive electrode of each pair is connected to the positive bus of the power generator, and a negative with a negative power bus of the generator, and the movable element of the emitter, for example, the membrane is combined with one or more positive and/or negative electrode or itself is one of the electrodes [description of the invention the application of the RF 94027257 And 61 H 23/00,1996].

For the treatment of vascular diseases of the extremities of the electromagnetic field intensity E. 200-300 and frequency 40-68 MHz combined with simultaneous pulse periodical hypobaric hypoxic stimulation [Ed.mon.The USSR 638339, And 61 N 9/00, 1978 ].

With this purpose it was proposed to jointly influence affected konecne vessels of the extremities with induction field 20-30 MT and a frequency of 20-30 Hz, that is carried out in the chamber [Ed. mon. The USSR 1475678 And 61 H 9/00, 1989].

It is reported that the simultaneous effect on the tumor shock wave pulse and a pulsed electric field, the amplitude of which exceeds a threshold field strength of the breakdown of the membranes of tumor cells, but less than the threshold field strength of the breakdown of cell membranes surrounding tissues and organs, improves the efficiency subcellular degradation until the complete cessation of tumor growth [RF Patent 2127615, And 61 N 1/32, 1999].

It is well known that physiological effects arising from exposure to electromagnetic fields on the body, are determined by the characteristics of these fields and parameters of current impacts. In this regard, the selection of characteristics influencing electromagnetic fields and modes of exposure is key and determines the effectiveness of medical procedures.

In all the above mentioned known methods of therapeutic effects of electromagnetic fields selection field characteristics were carried out:
empirically, when the characteristics of the electromagnetic fields were selected based on the desired beneficial result;
by choosing such characte, in those cases, when blood flow disorders were clear and the purpose of impact was the normalization of blood;
by forming electromagnetic fields, coinciding with the characteristics of the natural electromagnetic fields of the body.

In the latter cases, the selection of the measured natural electromagnetic fields was arbitrary and communication affecting artificial electromagnetic fields with nature's natural electromagnetic fields that exist in living tissue exposed to, can not be traced.

All the electromagnetic fields was not homogeneous in the sense that it does not ensure uniform exposure to the entire treated area, as:
was not optimized, the design of devices for generating and emitting the required fields to influence the organs and tissues of a living organism.

not produced normalization of the geometric characteristics of the electromagnetic fields in the area of impact;
no analysis of the biological effects of using non-uniform electromagnetic fields;
Wide variation accounted for in the known methods of the parameters of electromagnetic fields and their numerical values svidetel the STI.

One of the authors of the invention have already stated that when a wide range of equipment for electromagnetic therapy and with a significant volume of research on the reactions of the body systems to electromagnetic interference, as a rule, there are no biophysical justification of the choice of appropriate parameters of electromagnetic impacts and proposed in the Annex to the bone and vascular systems to formulate the concept of "biotechnol parameters of electromagnetic influence as follows: "it is necessary to create such currents in the tissues that form and geometry would be similar to the currents that occur in healthy, normally functioning, and the amplitude would correspond to the level of touch sensitivity of the patient" [Shchukin, S. I. Apparatus and system for beadequate electromagnetic therapy and active diagnostics. //Medical electronics.- 1999.- N 3.- C. 6-15].

The adequacy of the forms of self-currents J₁(t) and created using an external source currents J₂(t)) will be achieved, if
J₁(t) = SJ₂(t)
where S is a parameter, depending on the sensitivity of the sensor systems of the biological object (degree of activation of immune sisiemeye biological tissues [Shchukin, S. I. Devices and systems for electromagnetic individual therapy and active diagnostics. //Bulletin of Moscow State technical University, 1993.- # 4. - C 9-24].

In the above-mentioned sources of scientific information sets out the General principle views on theory of the formation of bone and vascular tissue of its own electromagnetic fields and identifies research areas that can afford to create an artificial electromagnetic fields are the most adequate to the natural electromagnetic fields generated by living biological tissue.

The applicant developed, customized and streamlined somewhat General terms theory, which allowed us to Express and to make practical recommendations for the normalization of the biological functions of any living tissue under the influence of artificially generated electromagnetic fields.

The main objective of the present invention is to optimize the effects on the biological functions of living tissues electromagnetic fields due to a single universal approach to the formation of the acting field.

The ultimate goal of this invention is to improve the efficiency and shortening the treatment time, the x tissues are formed his own weak electromagnetic fields, characterized by its own intensity, repetition rates and pulse shape. These fields consist of a quasi-permanent, associated with a stable fabric structure, the intensity of metabolic processes in it and so on, and the dynamic that occurs in the process of deformation fabrics in the functioning of the body. However, the main physico-chemical effects that generate electromagnetic fields are piezoelectric, electret and electrocapillary.

During the life of the organism, involving the variables of the dynamic pressure changes and the ratio of quasi-permanent and dynamic components of the self-electromagnetic fields.

[Shchukin, S. I. Apparatus and systems for electromagnetic individual therapy and active diagnostics. //Bulletin of Moscow State technical University, 1993.- N 4.- C. 9-24].

Own magnetic fields that occur in different organs and tissues differ in their characteristics. The characteristics of these fields vary with age; they depend on the physiological state of the corresponding organ or tissue and distorted in various pathologies and diseases the magnetic field, identical fields emitted by living tissues, it is not possible.

Long-term studies of the applicant, it was found that the most significant role in the formation of any living body's own electromagnetic fields belongs to the circulatory system - it is a result of the movement of blood through the blood vessels are field specific configuration with specific parameters and characteristics.

Was expressed and fully confirmed the hypothesis that, in violation of the biological functions of living tissue is changed and it generates an electromagnetic field and if this fabric impact that will lead to the restoration of the natural characteristics of its electromagnetic field, it will be restored and its biological functions.

The relationship of the main parameters of the electromagnetic field generated by the biological tissues subjected to pathological changes can be 20-70% of the nominal parameter values of the fields generated by healthy tissues.

This meant that in order to restore the natural electromagnetic fields of living damaged tissue would be best to have the who's following and the form of pulses to the natural fields of the corresponding healthy tissue, but with an intensity several orders of magnitude smaller.

This approach is universal in the sense that it involves any living tissue or organ electromagnetic fields most relevant to the natural electromagnetic fields emitted from the corresponding healthy tissue.

When exposed to this kind of point of application should serve as vascular network of the damaged tissue, which is mainly responsible for the formation of their own electromagnetic field in one or other living tissue.

The merits of the proposals of the applicant is that for the normalization of the biological functions of any living tissue in the damaged tissue act homogeneous electromagnetic field, aimed directly on the vascular network of the damaged tissue using electromagnetic field inducing current on the pulse frequency and the pulse shape matching and intensity by several orders of magnitude smaller than the corresponding parameters of the current logged during normal system operation flow corresponding healthy tissues during exposure to control the response of the vascular network of the body tissues on enosti response.

In order to normalize the biological functions of living tissues for therapeutic purposes, previously in the corresponding healthy tissues determine such characteristics of the intrinsic electromagnetic field of the cloth, as the repetition rate and the pulse shape and intensity of the electromagnetic field.

Such information may be obtained directly or in advance on the basis of experimental studies from the literature or by other means, for example by the method of calculation.

This information can be obtained using such known techniques, such as Doppler ultrasound, impedance realtystore, blood pressure measurement and subsequent processing of the data, e.g., digital spectral analysis.

On the basis of the received information is formed of an artificial electromagnetic field, and the repetition frequency and the pulse shape of this field must be the same as that of the electromagnetic field emitted from the corresponding healthy tissue, and its intensity should be several orders of magnitude smaller.

The pulse frequency natural electromagnetic field of healthy tissue usually lies at the limit of the pulse can be set equal to the pulse frequency of the electromagnetic field of healthy tissue but you can increase or decrease by 2-5 times.

The form of pulses of electromagnetic fields healthy tissue is bell-shaped, and should in General play when forming external influencing fields.

In a healthy body's own electromagnetic fields induce, as determined by the applicant, a current density of 10^-3- 10^-2A/m².

Usually the intensity of the impinging electromagnetic fields in the impact zone and, accordingly, the density of the induced currents, must be 100-1000 times less than the intensity of natural electromagnetic fields and induced them currents observed in healthy tissues.

Therefore the external field must induce in the zone of influence of current density of 10^-6- 10^-4A/m².

Studies showed that to solve this problem affecting the electromagnetic field with a pulse repetition rate of 0.6 to 3.0 Hz should have an intensity of 0.5 to 5.0 MT.

However, depending on the condition of the damaged tissue, its location, being patient and from other circumstances, the intensity of the field may be another that is not it is against the intensity of the field of healthy tissue aims to limit the impact levels, providing information agreement with the biological object, when the parameters influencing electromagnetic fields significantly less self-products of biological tissues.

There is a perception that external magnetic fields can affect a living organism only when the sensitivity threshold of the biological object, and the nature of the impact depends on the parameters affecting the field: at a moderate intensity field manifests its impact on the body, and at a higher intensity and energy [Plekhanov, F. Electricity, magnetism, information and living systems //Living systems in electromagnetic fields. - Tomsk: Publishing house of Tomsk state University, 1978. - N-3-8.].

The so-called information exposure is characterized by the influence of electromagnetic fields directly on the process of functioning of a biological object, which adjusted the acting field, and the observed biological effects due to changes in the biological activity of organs, systems and tissues of a living organism.

The energy level of exposure to physical causes, and then and biological effects is NCLI biological object.

Within the present invention provides the exposure to electromagnetic fields only on biological living tissue directly.

Thus formed external electromagnetic fields interact primarily and directly on the vascular network of tissues and have a direct impact on this fabric formed its own electromagnetic field.

The fundamental difference between the proposed method against known is that previously used the known methods of electromagnetic influence on the system of blood vessels was aimed exclusively normalization is clearly impaired blood flow and kroveobraschenie adjacent tissues, and in the proposed method, this objective is intermediate, since the ultimate goal is to restore the characteristics of the natural electromagnetic field, produced by a properly functioning appropriate living tissue that makes and normalization of biological functions corresponding to living tissue, violated not only by reason of the violations of its blood supply, but also for other reasons.

An important condition for the implementation of the proposed method is the effect on tissue homogeneous ele is yavlenie characteristics of the field, inherent to healthy tissue. Heterogeneous affecting the electromagnetic field may not have the same impact on all areas of the vascular network of the tissue and to facilitate the emergence of adequate reactions, complicating the recovery process of the affected tissue normal field parameters characteristic of healthy tissue.

The latter is highly important, as studies have shown a significant dependence clinical results from the amplitude of electromagnetic waves. This means that if the condition of homogeneity of the field is substantially not performed, i.e., if the coefficient of heterogeneity exceeds 25%, then some parts of the body are in a zone of vasomotor reactions, other - dilatator, and others in the area relative indifference to electromagnetic effects. This leads to competition vasomotor reactions and reduces the overall efficiency of the treatment effect.

The homogeneity of the acting field is provided by the number and the geometric dimensions of the acting inductors.

When performing medical procedures control the response of vascular tissue at the impact in terms of blood flow and adjust the parameters of blood flow. Dynamic indicators, such as blood flow velocity, shock and minute amounts of blood, it is preferable to control for patients angiology and trauma profiles. Rhythmic indicators, such as heart rate, better control for patients cardiac profile. It is desirable to control the dynamic and rhythmic parameters of blood flow in parallel and synchronize impact with rhythmic indicators of blood flow.

This impact can be made in moments of achievement indicators the rhythmic flow, peak values (i.e. systole or diastole), but may be delayed or ahead of the moments of the peak values of these parameters.

To control the blood flow indices can be any known methods, for example using impedance recordingmeeting systems. Indicators of blood flow can be detected directly in the field, affected, or in the main blood vessels, as changes in local blood flow in the tissue affect the performance of blood flow in large vessels and these changes can be detected and registered.

As already noted, the natural electromagnetic fields of organs and tissues experiencing fluctuations within a certain range of values of their parameters.

In this regard, affecting the electromagnetic field used for determining how the fact of the response and its magnitude, can be characterized by a certain range of values of basic parameters, which can smoothly change to optimally set the specific parameters influencing the field, giving the distinct response of the individual patient.

However, for these purposes can be used, and electromagnetic fields with stable values of the key parameters that are changed stepwise.

Setting the parameters affecting the field, giving the desired in a particular case, the magnitude of the response, in a similar way to optimize this invention, use artificial homogeneous electromagnetic field inducing current, pulse frequency and pulse shape matching and intensity by several orders of magnitude smaller than the corresponding parameters of the current logged in the normal operation of the corresponding healthy tissues.

Typically, the frequency of exposure to electromagnetic fields is set as daily, but can be applied to other schemes. The duration of a single procedure and cycle duration of treatment depends on many factors and is determined individually. However, on average, a single procedure takes 15-30 minutes, and the cycle of treatment is 10-20 procedures.

Thus, to restore the normal characteristics of their own electromagnetic fields damaged organs and tissues should, at least, to affect these organs and tissues homogeneous external electromagnetic fields, pulse frequency, pulse shape and intensity of which the above manner consistent with the characteristics of the electromagnetic fields created by the corresponding healthy tissues and organs.

The above-mentioned parameters of the electromagnetic polonich fields, and compliance with these parameters guarantees the achievement of the desired biological effect.

These settings on their own electromagnetic fields healthy tissue (repetition frequency and pulse shape, intensity) are determined by the functioning of the system of blood circulation, making the main contribution to the formation of the electromagnetic field created by biological objects, and their playing characteristics of artificial electromagnetic fields determines the normalization of the indicators field of the damaged tissues.

However, as was determined experimentally, to improve the adequacy of artificial electromagnetic fields of the natural and, consequently, to increase the effectiveness of treatment, it is desirable to additionally take into account such factors involved in the formation of their own electromagnetic fields organs and tissues, as the frequency of mechanical vibrations of the walls of blood vessels running through these organs and tissues.

This parameter is not directly related to indicators of the system of blood flow to and from these identified parameters displayed can not be. To establish the necessary experimental studies on autopsy material.

When forming artificial affecting fields is taken into account, any biological tissue will be affected and what blood vessels it is penetrated. Knowing from the preliminary experiments, what is the frequency of mechanical oscillations of the respective walls of the blood vessels, the size of the mechanical frequency is converted into the amount of electromagnetic frequencies, and the latter is introduced into the characteristics of the impinging electromagnetic field.

In other words, influencing the electromagnetic field preferably should include a component, inducing a current with parameters relevant parameters of the current recorded by mechanical vibrations of the walls of blood vessels, penetrating the tissue affected.

If the impinging electromagnetic field, in terms of repetition rate and pulse shape and intensity can be attributed to low-frequency, electromagnetic field simulating the mechanical vibrations of the walls of blood vessels, shall be assigned to a sufficiently high frequency.

In General the latter are characterized by the following parameters - pulse frequency of 8.0 to 15.0 Hz, the shape of them is bound to be carried out by any known method, in particular through the use of broadband generator and an inductor, having a filter, shut-off field with unnecessary frequency or by using a generator that generates an electromagnetic field only with the required frequency ranges.

Thus, in the optimal case of the implementation of the present invention use artificial homogeneous electromagnetic field inducing current, pulse frequency and pulse shape matching and intensity by several orders of magnitude smaller than the corresponding parameters recorded during normal operation of the corresponding healthy tissue overlaid with a uniform electromagnetic field inducing current matching characteristics with the current recorded by mechanical vibrations of the walls of blood vessels permeating the corresponding healthy tissue.

For the practical implementation of the described method can be used device capable of forming a homogeneous electromagnetic fields, reproducing the characteristics of the electromagnetic field close to their own fields of healthy tissues of the body.

It is necessary that such a device is a clique indicators of blood flow in the vascular network of the tissue to electromagnetic interference 4, block programming parameters of the created electromagnetic field and modes of its impact on the fabric 5 and unit performance and maintain the programmed parameters and modes 6, the generator 1 provides for the creation of bell-shaped form of the current pulses with the frequency of repetition in the range of 0.6 to 3.0 Hz.

Another option for practical implementation of the proposed method may be a device for electromagnetic effects on living tissue, in which the electromagnetic coil 2 is arranged to generate a homogeneous field, inducing currents with pulse frequency of the bell-shaped form of 0.6 to 3.0 Hz and with a pulse frequency sinusoidal 8,0-15,0 Hz, intensity of 0.5 to 5.0 MT, while it contains a block of programming parameters of the created electromagnetic field and modes of its impact on the fabric 5 and unit performance and maintain the programmed parameters and modes 6.

However, optimal implementation of the proposed method is a device optionally contains a sensor pulse blood 7 mounted on a biological object 3, the associated block synchronization pulses electromagneticradiation parameters and modes of exposure 6 contains directional current pulses 9, connected with the output amplifier 10, and the coil of the electromagnetic inductor 2 are divided into groups, each of which is directly connected to the output amplifier 10.

In Fig.1 and 2 show respectively a General block diagram of the proposed device and one of the specific variants of its execution.

In Fig. 1 shows a generator 1, the electromagnetic inductor 2, affecting the biological object 3, the display unit response indicators of blood flow in the vascular network of the tissue to electromagnetic interference 4, block programming parameters of the created electromagnetic field and modes of its impact on the fabric 5 and unit performance and maintain the programmed parameters and modes 6.

In Fig. 2 shows a preferred variant of the described device comprising a generator 1, the electromagnetic inductor 2, affecting the biological object 3, the display unit response indicators of blood flow in the vascular network of the tissue to electromagnetic interference 4, block programming parameters of the created electromagnetic field and modes of its impact on the fabric 5, unit performance and maintain the programmed parameters and clip frame the organization of pulses of electromagnetic fields 8.

When this unit performance and maintain the programmed parameters and modes of exposure 6 further comprises a pulse distributor DC 9 connected to the output amplifier 10, the signal frequency of heart-throbs 11, shaper delays 12, the divider pulse period blood on ten of the 13 intervals.

Block programming parameters of the created electromagnetic field and modes of its impact on the fabric 5 contains the control block shaper delays 14, the control unit synchronization mode 15, the setting unit forms the output current 16.

In addition, the device includes a level indicator output current 17 and the timer 18, the power supply unit 19 (not shown conventionally).

At the beginning of the procedure, exposure to electromagnetic fields generator 1 produces an electrical pulse shape and repetition rate of which is set a block of programming parameters of the created electromagnetic field and modes of its impact on the fabric 5. These pulses arrive at the input unit performance and maintain the programmed parameters and modes 6, with which the current pulses are received by the electromagnetic inductor 2. Electroma object 3. The display unit response indicators of blood flow in the vascular network of the tissue to electromagnetic interference 4 allows you to control the blood flow parameters and their changes over time when exposed to electromagnetic fields that are used to correct the modes and parameters of the exposure unit 5.

In a variant of the described device of Fig. 2 generator 1, the electromagnetic inductor 2, affecting the biological object 3, the display unit response indicators of blood flow in the vascular network of the tissue to electromagnetic interference 4 operate in the same manner, and the block programming parameters of the created electromagnetic field and modes of its impact on the fabric 5 contains the control block shaper delays 14, the control unit synchronization mode 15 and the mounting block form of the output current 16. Unit performance and maintain the programmed parameters and modes of exposure 6 further comprises a directional current pulses 9, the output amplifier 10, the signal frequency of heart-throbs 11, shaper delays 12, the divider pulse period blood on ten of the 13 intervals.

The control unit driver delays 14 powolny pulse blood. Modes with a time delay of pulses of electromagnetic influence regarding hemodynamic phases of the cycles are of particular interest and to ensure these modes are block shaper delays 12, which produces the necessary delay and provides phase synchronization pulses of electromagnetic field, and the control unit driver delays 14. The control unit driver delays 14 provides a choice of seven fixed time delay and no delay - Delay 0", which are set by external bodies.

The control unit synchronization mode 15 allows you to set synchronized or automatic modes of electromagnetic influence.

To obtain phase synchronization own quasi-periodic rhythms pulse blood and generated by the system of inductors electromagnetic fields, the period of electromagnetic influence is divided in block 13 on ten equal intervals of time. In fact, the multiplication register current heart rate ten times while maintaining phase relationships for each hemodynamic cycle. In Khidoyatova current can be set as desired using the controls form in accordance with the doctor's appointment and guidelines, including can be used specially created "samples stored in the memory unit forms the output current 16.

Generator 1 generates a fixed frequency in the range of 0.8 to 12 Hz for the procedure of electromagnetic effects in the synchronized automatic mode, which are useful for therapeutic procedure of electromagnetic exposure settings, adequate bone tissues, traumatology, sports medicine and cosmetology.

The generated voltage pulses are amplified in the unit of the output amplifier 10, which represents a source of current, voltage controlled to the required value of the output current. The indicator of the output current level 17, which represents an led matrix displays actually flowing through the working part of the current, receiving the value of the output current from the current sensor - resistance, connected in series with the electromagnetic coil 2, which is the working part and the load output of the power amplifier 10. When this coil electromagnetic inductor 2 are divided into groups, each of which is directly connected to the output amplifier 10. the s output current is directed in one in another group unit of the pulse distributor 9.

Bisynchronous electromagnetic exposure is carried out in cycles of pulse blood using optical sensor pulse blood 7 infrared range, which is made in the form of an optocoupler with open optical channel. The sensor 7 registers the signal pulse blood, using the principles photoplethysmographic transducers "reflection". Check photoplethysmographic signals is possible in continuous and pulsed mode of the illuminator. More complicated pulse mode illuminator allows you to get less burdened network interference, noise photoplethysmographic signals and information about the pulse volume, which allows us to achieve a more stable synchronization. Input signal frequency of heart-throbs 11 receives continuous (analog) signals from a remote optoelectronic sensor pulse blood filling 7, in which the unit 11 is converted into the digital control pulse synchronization. At the beginning of the control pulse synchronization adopted the middle of the systolic wave fot the disorder in the synchronized mode.

How to use sensor pulse blood 7 in the described variant of the device is as follows. Before the procedure the device previously include at the time of 4-5 minutes and with the help authorities establish the necessary procedures and required forms, amplitude, timing mode and time delay. Optoelectronic sensor pulse blood 7 install without significant pressure on the finger (from palm), legs, ear lobe or on the body surface in areas close to large blood vessels. While working surface ("window" sensor 7) must be in contact with the skin surface. Before installing the sensor 7, it is recommended to wash the place of overlay sensor 7 with warm water and soap or wipe with alcohol to ensure transparency of the optical paths of direct and reflected infrared rays.

After the sensor 7 is installed correctly, you should wait with 10-25 until the rhythmic display of the patient's pulse. The criterion of correct installation is stable, uniform flashing synchronization, which coincides with the pulse of the biological object(prednaznacenija sustainable synchronous actions is required immobility of the patient; the location of the sensor 7 and the connecting cord must also be stationary. It is known that the level of surface flow have a significant influence of external temperature conditions that are associated with vasomotor reflexes. Therefore, for stable synchronization needed a comfortable temperature conditions in the room. When obtaining a robust synchronization for the start of electromagnetic influence to press the start button, this starts a countdown procedure (in direct mode or countdown) and the working part of the device - electromagnetic inductor 2 will start creating corresponding to the selected modes of the electromagnetic field.

Simultaneous use of reopletizmografiy equipment and the use of electromagnetic effects are not an obstacle to the use of the sensor pulse blood filling 7 and synchronization mode. However, when the registration of the electrocardiogram during sessions electromagnetic effects possible significant distortion of registered electrocardiogram due to the effect of alternating electromagnetic fields.

The timer 18 is the magnetic influence up to 60 minutes in increments of 5-10 minutes The timer 18 allows you to set the desired duration (temporary dose) procedures electromagnetic interference and incorporates appropriate controls with digital time indicators. To determine the current exposure time are two seven-segment-led - units and tens of minutes. Reset the timer 18 and the stop of the described variations of the device is performed automatically after the set time of the procedure, but can be manually stops the specified timer time electromagnetic influence.

Listed below are the main technical features implemented in one embodiment of the proposed device. The proposed device allows healing sessions biosynchronisation by the pulse volume electromagnetic therapy with a maximum range of change of the magnetic field at the geometric center of the impact area of 0.5 to 5.0 MT, with the unevenness of not more than 25%. The frequency range of the pulses of electromagnetic fields from 0.6 to 3.0 Hz and 8.0 to 15.0 Hz. Typical duration of exposure 20-40 minutes In the structure of the proposed device uses a remote infrared sensor vs the e device is equipped with a special protection against electric shock. Dimensions HH (e-block), the mass not exceeding 18 kg, the presence of the timer, controls, modes and exposure parameters. The amplitude of the induction in the working area of the inductors to 5,025% MT. The synchronization accuracy systolic front pulse of the blood supply to the biological object 25 MS, the presence of automatic and synchronous with the pulse mode, the pulse frequency of the field in automatic mode 1,010% Hz. Form field pulses composing, display form with 10 levels of amplitude. Procedural watch timer with a capacity of not less than 60 min with discrete installation in 10-minute intervals and auto shut-off pulse of the field. Class electrical safety of the device 01 type according to GOST R. 50267.0-92. Food W%, GC% consumed from the AC power 300 VA.

Currently designed, manufactured and tested modifications of the technical performance of the proposed device. The use of microprocessors as part of the proposed device can significantly reduce the number of electronic circuit components, to improve reliability of technical means to provide ergonomic operation modes vozdeistviyami realization of algorithms for signal processing pulse blood, including digital
filtering the primary signal, the introduction of adaptive time zones insensitivity and Gating moments sync hemodynamic cycles. The flexibility inherent in the software implementation of management tasks allows without changing hardware hard patterns to make additions, corresponding to the results of new fundamental and applied research in the field of interaction biaxinclarithromycin electromagnetic fields with biological objects and operative to support the technical and methodological improvements in the means of low-frequency biosynchronisation therapy.

Practical use of the proposed method and a device designed for carrying out the method, lets you broaden the scope and increase the effectiveness of electromagnetic fields for therapeutic purposes, which could result in a reduction of treatment time and reduced the overall impact on the biological object to electromagnetic fields. The proposed method and device are universal and can be used for therapeutic treatment of damage to any organs and tissues, when electromagnetic who learn the hard conditions and pathologies, associated with explicit or implicit defects of the vascular system, although it can not limited. This method can be applied not only for the treatment of patients with trauma and surgical, and therapeutic profile, it can be used in sports medicine and cosmetology.

The method has been widely tested in leading medical institutions in the clinics of the Russian State Medical University, Central research Institute of traumatology and orthopedics, Central Institute of surgery, the Republican children's clinical hospital, Children's city clinical hospital n.a. M. F. Filatov, Gorky oblast diagnostic center, etc.

In particular, the effectiveness of the method was tested in the treatment of disorders of the main flow, caused by the trauma of the main vessel in an accident (11 observations), or complications after operations on vessels as a result of their thrombosis (6 observations). In such situations there is a serious neurotrophic complications, including ischemic contractures, the treatment of which today is associated with long-term rehabilitation, microsurgical reconstructive surgery, and p is ptx2">

In addition to the above contingent of patients, met the children experienced a "typical" injury (closed fractures without features, bruises) which later develop complications, which are based on the vascular factor (nerastas fractures, osteomyelitis, ischemic contracture). For explanation of such complications is sometimes not enough arguments, because the management of such patients were not also associated with medical errors (incorrect reduction and immobilization).

Conducted angiographic studies have shown that the basis of such complications are vascular malformations that do not manifest themselves in a period of prosperity and implemented with injuries. Of the 15 studies in this group have 6 children found congenital anomalies of great vessels (40%). This is mainly manifested in the agenesis (2 observations of 13.5%) or abnormal development of the main vessel and the absence of one of the Palmar arches (4 observations - 27%). Knowledge of such features requires early diagnosis of probable vascular malformations and anomalies in cases where the observed atypical course of reparative processes in injured children. This allows to adequately rebuild medical tactics and sbeattie occur after vascular operations. It angiography clearly and quickly responds to the question about the presence of obstruction of the lumen of the main vessel and allows you to purposefully move to eliminate this complication.

With the aim of increasing the blood supply to the damaged limb, we have applied the proposed device.

In 3 patients (20% of the group) using angiography revealed that ischemic contracture was due to prolonged obstruction of the lumen of the main vessel by a blood clot. In such cases, after biotechnolo electromagnetic effects possible recanalization of the vessel, which leads to stimulation of reparative processes of the soft tissues without additional surgical intervention. First there is an increase in the development of collaterals, which initially provide regional blood flow and maintenance of reparative processes, and after recanalization of a major vessel they support the required level of blood supply to the limb.

Rheovasography, conducted in patients with ischemic contracture of the limbs, was rapid method for monitoring the effectiveness of treatment. Given the relative paucity in each age group paulinum electrophysiological test. Generally, there was a General trend towards a significant increase in pulse blood filling in the segment of the affected limb in patients with severe toning of small vessels and reducing the elasticity of the walls of large arteries. Such functional changes were noted in the symmetric uninjured limb, but to a lesser extent, while maintaining the elasticity of the walls of large arteries. As alignment hemodynamic parameters was clinical improvement after a month and a half.

Local thermometry was simple and effective method of control over the course of recovery of regional blood flow. Her testimony is fully correlated with the dynamics of days.

Radiographs were performed in the affected by the presence of bony injury with the purpose of primary diagnosis but also for monitoring osteopatia. It is noted that the presence of malformations of the great vessels dramatically reduces the reparation of bone tissue, leading to the formation of false joints, the occurrence of osteomyelitis. It is important that even surgery-transplantation microsurgical techniques do not always give a positive effect in this group of patients. Only after vosstanavlivaet, that this is possible using the proposed method of electromagnetic influence.

Treatment of electromagnetic effects in patients with impaired regional blood flow through the main type was conducted on an outpatient basis. Clinical observation has shown that the electromagnetic interaction is well tolerated even by children. If Volkmann contracture treatment was started with the impacts of not less than 15 sessions per course, with a repetition of every month, with the purpose of stimulation of peripheral blood flow. The first improvements in the form of increased sensitivity, the appearance of finger grips observed after 3-4 months.

Positive clinical dynamics is gradual. Six months after starting treatment, as a rule, the skin becomes pink and comparable to the intact limb, becomes a distinct vascular pattern. After 1-1 .5 years the phenomenon of ischemia fully cropped, and begins rehabilitation therapy, which includes physical therapy, massage, mechanotherapy. Without improving regional blood flow to a sufficient level such treatment according to our observations does not work. It should be noted that after 3-4 is after 3-4 disappeared completely. As a rule, sufficient was 10-15 sessions for patients, which impacts was conducted in the early postoperative period.

The effectiveness of the proposed method was evaluated with clinical and functional recovery positions of regional blood flow and recovery of reparative processes. For an excellent result was considered mild ischemia in the early stages before the development of complications, for good recovery of regional blood flow in late (>6 months) periods of ischemia with full recovery of limb function after z-shaped tendon plasty. Satisfactory results implied partial recovery of regional blood flow, which ensured the maximum effect of microsurgical plastic surgery, unsatisfactory - the complete ineffectiveness of electromagnetic influence.

Among the obtained results: excellent - 8 (25%) good 9 (28%), satisfactory - 15 (47%). Poor results were not. Complications in this group of patients associated with the use of the proposed device is not marked.

The foregoing is illustrated by the following clinical Examples.

Example 1. Sick boy oz of both bones of the right forearm.

Three years ago, I had a closed fracture of both bones of the right forearm. Initially held closed reposition imposed a plaster of Paris splint is placed. There was a pronounced swelling of the affected limb. Three days after reposition produced by Ilizarov. By the end of the first week there were fever (up to 38 -39^oC. was Carried out specific treatment on the onset of osteomyelitis is without effect. After 2.5 months about the functioning of the fistula was sequestrectomy. The treatment proved ineffective, formed a false joint of both bones of the right forearm.

Starting from the fifth month after trauma is formed ischemic contracture of the right upper limb.

Given the severe pathologic process and extremely low reparative ability of biological tissues, it was decided to conduct angiography, which revealed that the forearm functions of the radial artery and the deep Palmar arch. In the upper third of the radial artery is not part of the main channel and flow from upstream of the Department is carried out by the collaterals. The division of the brachial artery in the upper third of the forearm (the anomaly), when Aetna artery, in the bloodstream which is retrograde through the deep arc. Thus, the injured limb was supported by a malformation of the blood vessels of the forearm. In these conditions, they vascular graft is possible only with one of the extended return of the branches of the ulnar artery.

On the seventh month autoplastic false joint fragment of the fibula of the right leg using extramedullary plate. Happened rejection plate intensified fistula. After removing the plate again imposed the Ilizarov and antibiotic therapy was conducted.

Eleven months after the injury held microsurgical operation on autoplastic fibular bone with the left leg. Immobilization in the Ilizarov frame. Two months after surgery, fracture occurs transplant, about which produced osteosynthesis spoke of Kirchner. Unfortunately, it also had to remove after 2.5 months in connection with speciem osteomyelitis.

Given the presence of congenital vascular malformations in the right forearm decided to spend treatment by electromagnetic influences. Previously, to determine the optimal modes impact gnanam field with a pulse frequency of 0.6 Hz to 3.0 Hz and an intensity of from 0.5 MT to 5.0 MT. The shape of the pulses in this case was bell-shaped.

These field parameters were within the values of the natural electromagnetic field created by healthy tissues of the human upper limb, but with reduced 1000 times the intensity.

When exposed to these changing electromagnetic field is detected the response of the vascular network of the tissues of the forearm at impact.

The fact of the response and its magnitude was determined as a function of changes of blood flow velocity, which was measured by the method of ultrasonic dopplerography.

It was found that the bell-shaped pulses, the maximum response is observed when the pulse frequency of 1.2 Hz and intensity, equal to 3.5 MT.

On this basis further used affecting the field were given these parameter values.

The homogeneity of the acting field provided extensive design electromagnetic inductor, completely thrilling region of the forearm.

The frequency of the electromagnetic field was consistent with the pulse rate of the patient and had a delay of 10 s after reaching its maximum.

As a result of the treatment of fistulas ceased to function, consolidation of fragments, improved function of the right upper limb.

At all stages of treatment by electromagnetic irradiation was performed dynamic reovazograficheskie control. Before treatment on the part of the injured extremity there was a sharp depression of pulse blood filling and substantial obstruction of the venous outflow marked reduction in the elasticity of the walls of arteries with intact tone of collateral vessels. By symmetric intact limb pulse volume was slightly increased when normal tonus of vessels of all calibers. After treatment the asymmetry coefficient of the blood flow of the upper extremities decreased to 9%, while the pulse volume of the right forearm was 10% above the norm, the elasticity of the arteries, peripheral vascular tone and venous outflow is within normal limits. Clinically the patient has improved the function of the right hand, appeared finger grips, consolidation of fragments occurred without additional surgical vesatile tissue approached the parameters of the electromagnetic field, form healthy tissue, whereas before treatment values of these parameters deviated from the nominal values by 65%.

We can conclude that congenital malformations of limb vessels lead to lower reparative abilities of injured extremities, causing severe complications including osteomyelitis and ischemic contracture. These are based on the processes blocking the main circulation, without recovery of which no reparation processes of biological tissues. In such conditions, the use of surgical treatment, including microsurgery, it is often ineffective. To calculate the recovery is possible only after the restoration of regional blood flow. Application of the proposed method allows to achieve this, which makes it promising for further plastic surgery and increases the effectiveness of treatment in this difficult group of patients.

Example 2. Patient Anastasia A., 5 years, history N 4112, turned 12.09.93 about post-traumatic ischemic Volkmann contracture of the right upper limb. Three months ago, fell in the yard with metal structures, has been closed Razmyslov fracture of the right shoulder to the definition. On the third day due to persistent swelling and displacement of fragments produced open reposition with osteosynthesis spokes of Kirchner. In operation, the preparation of the brachial neurovascular bundle, damage which was not noted.

After surgery, the limb was in a plaster of Paris splint is placed without tight immobilization. The girl constantly complained of pain in the operated hand, the weakening of the sensitivity. A month and a half, by removing a plaster splint revealed persistent extensor contracture of the right upper limb from the elbow to the interphalangeal joints of the brush, which has quickly become the character ischemic. Grew rapidly hypotrophy of the right forearm, the skin became waxy, lost sensitivity, appeared peeling, and sores on the bends, the local temperature of 27.5^oC on the damaged side and 31.8^oC intact. Such neuro-trophic disorders doctors couldn't explain and the child was sent to the clinic for angiographic studies. On angiograms revealed thrombosis of the brachial artery in the lower one third length of 8 cm, which completely blocks krovosnabjeniem great saphenous vein of the thigh, from which the parents refused.

It was decided to start conservative treatment of electromagnetic effects.

To determine the optimal modes of the electromagnetic field in the shoulder region of the right hand was the effect of gradually changing electromagnetic field with a frequency of pulses from 0.6 Hz to 3.0 Hz and an intensity of from 0.5 MT to 5.0 MT and with the bell-shaped pulse shape.

It was found that the most clear response from the vascular network of the damaged tissue causes a homogeneous electromagnetic field with a frequency of 1.0 Hz, with a bell-shaped pulse shape and intensity of 4.0 MT.

These parameters set the parameters affecting created fields.

On influencing the electromagnetic field was imposed another electromagnetic field with a frequency of pulses, equal to 12.0 Hz, pulse shape sinusoidal shape and intensity, equal to 0.8 MT.

The second additional electromagnetic field induced current with the parameters corresponding to parameters of the current induced mechanical vibrations of the walls of the brachial artery that occurs during the normal functioning of the upper limb when biological material.

The possibility of combining these fields were provided by the design of electromagnetic inductor, equipped with the necessary filters for cutting off electromagnetic fields with different parameters.

The frequency of exposure to electromagnetic fields has been synchronized with the frequency of bullsonparade and was ahead by 5 after reaching its maximum.

The duration of treatments was 30 minutes, a single course of treatment consisted of 20 procedures that were performed daily.

To assess the effectiveness of treatment was continuously carried out reovazograficheskie research. Before treatment with damaged limbs eographically signal was not detected. On the background of treatment with 1.5 month appeared first clinical improvement in the appearance of the sensitivity, rise local temperature to 28.3 With healed ulcers, stopped peeling skin, appeared sweating on the palm. At this time, rogramme recorded a sharp decline in the elasticity of the vascular wall, a spasm of peripheral vessels, abruptly obstructed venous outflow. The asymmetry factor in the blood of healthy limbs - 72%.

This period was also conducted sessions is ü, because it caused severe pain and was ineffective. However, the appearance of pain during exercise was regarded as a positive sign.

6 months after the start of treatment appeared capture of the first finger and the minimum movement joints in the hands. The temperature of the skin of the forearm was 30,1^oC to the right and to 32.2^oC on the left. On rheovasography showed normalization of vascular wall elasticity while maintaining the spasm of small blood vessels and sharply reduced venous outflow. The asymmetry factor of 59%. Control angiograms main flow is missing, but expressed a dense network of collateral vessels at shoulder and forearm, which explains the positive clinical dynamics. There were 4 courses for 20 treatments, with intervals of 1 month and it has been a rapid positive changes in the form of restoration of all types of finger grips, full recovery of skin sensitivity. The local temperature on the right forearm was higher than on the intact limb (33,2^oC and 32.5^oC, respectively), indicating intensive regional blood flow. On rheovasography increased pulse volume with normalization of tone small ). The asymmetry factor of 12%. It was noted restoration of patency of the right brachial artery throughout, with prominent collateral vessels.

Clinically, the application of the proposed method provided a significant improvement in the patient's condition: the Function of the limb is fully recovered, the right hand does not lag behind in growth, although still has a small hypotrophy of muscles of the forearm, the child is actively using hand. However, the full extension of the fingers is impossible due to scarring of the long flexor of the toes. Given the success of conservative treatment, microsurgery angioplasty, it was decided to refuse. The question of the tendon plasty for full recovery of the movements of the fingers of the hand.

At this period the values of the parameters of the electromagnetic field traumatized tissue did not differ from the values of the parameters of the electromagnetic field generated by healthy tissue, although before treatment electromagnetic effects of the mismatch parameter values was 70%.

Obviously, the effectiveness of conservative rehabilitation of main blood flow in the limb under the action of electromagnetic fields can in some cases bolognini transferred from ischemia significantly reduced.

Thus proved the efficiency of the proposed method of electromagnetic effects in trauma patients to stimulate reparative processes.

The proposed method and the device allow you to control the response of the vascular network of the tissue of the body, as measured by the change of the dynamic indicators of blood flow, and to realize the impact mode, the calling, the maximum dynamic response indicators of blood flow, also allow for the impact mode, synchronized with rhythmic blood flow parameters. The device synchronizes the pulses of electromagnetic fields with the phases of the pulse of the blood supply to the optical sensor. By setting different delay field pulses from mid-systolic front cycle pulse blood maybe a different way to get into phase pulse of blood that can deliberately control the tone of the vascular wall. Therefore, this effect can be called the best individual. Causing constrictio or dilation of an arterial channel may directly control the main flow. Therefore, the use of the method and device n the identification of the impact mode, calling the maximum dynamic response indicators of blood flow and synchronized with rhythmic blood flow parameters. In the method, the influence exercised by the electromagnetic field intensity from 0.5 MT to 5.0 MT, inducing a current with a pulse repetition rate equal to 0.6 to 3.0 Hz and bell-shaped form. At the same time on the damaged tissue may additionally influence of a homogeneous magnetic field, inducing a current with parameters matching the parameters of the current recorded by mechanical oscillations of the blood vessels permeating the corresponding healthy tissue. Additional impact exercise electromagnetic field intensity of 0.5 to 5.0 MT, inducing a current with a pulse repetition rate of 8.0-15 Hz and sinusoidal. Thus the proposed method biotechnolo electromagnetic influence is a highly pathogenic factor in the treatment of patients with major type of violation regional blood flow. Equally it is possible to recommend beadequate electromagnetic effects not only for the treatment of disorders of the main flow, but also for the prevention of early thrombosis after angioplasticeskih many body systems due to immobility, pathological condition in the postoperative period or after excessive on grusak, to activate the immune system and stimulation of protective forces of an organism. therapeutic effect is achieved stimulating effect on metabolic processes in body tissues, leading to positive changes of the functional state of regulatory systems.

Indications for use are, in particular, obliterating diseases of lower extremities, thrombophlebitis, endarteritis, varicose veins, phlebitis, vasculitis, ischemic heart disease, cerebrovascular circulation, prevention of vascular complications after re limbs and tissue flaps, poorly-granulating wounds and trophic ulcers, swelling of different etiology (trauma, allergic), complications after injuries and bone plastic surgery, diseases of the skeleton, myositis, sprains, soft tissue injuries, plastic surgery on the nerves, diseases of internal organs and tissues.

1. The method of normalization of the biological functions of living tissues by acting on the damaged tissue electromagnetic field, characterized in that the impact of exercise aimed directly with the pulse frequency and pulse shape matching, and in intensity by several orders of magnitude smaller than the corresponding parameters of the current logged in the normal operation of the corresponding healthy tissues during exposure to control the response of the vascular network of tissues for these impacts, as measured by improvement in blood flow, and the influence exercised by taking into account the intensity of the response.

2. The method according to p. 1, characterized in that in the process of action control response of the vascular network of tissues for these impacts, as measured by the change in the dynamic parameters of the flow, and the influence of exercise mode, causing the maximum dynamic response indicators of blood flow.

3. The method according to p. 1, characterized in that the exposure is performed in the mode, synchronized with rhythmic blood flow parameters.

4. The method according to p. 2, characterized in that the exposure is carried out in a mode that causes the maximum dynamic response indicators of blood flow and synchronized with rhythmic blood flow parameters.

5. The method according to PP.1 to 4, characterized in that the influence exercised by the electromagnetic field intensity of 0.5 to 5.0 MT, inducing a current with cha - , characterized in that at the same time on the damaged tissue is additionally affected by a homogeneous electromagnetic field inducing current with parameters matching the parameters of current, caused by mechanical vibrations of the walls of blood vessels permeating the corresponding healthy tissue.

7. The method according to PP.1 - 6, characterized in that the additional impact of implementing electromagnetic field intensity of 0.5 to 5.0 MT, inducing a current with a pulse repetition rate of 8.0 to 15.0 Hz and sinusoidal pulse shape.

8. Device for electromagnetic effects on living tissue, comprising a generator and an electromagnetic inductor affecting biological object, characterized in that it further comprises, a display unit response indicators of blood flow in the vascular network of the tissue to electromagnetic effects, the block programming parameters of the created electromagnetic field and modes of its effects on tissues and unit performance and maintain the programmed parameters and modes, the generator provides the creation of the current bell-shaped pulse shape and frequency of their repetition in the range of 0.6 to 3.0 Hz.

9. The mustache is output at a biological object and its associated block synchronization pulses of the electromagnetic field.

10. The device under item 8, characterized in that it further comprises a display unit response indicators of blood flow in the vascular network of the tissue to electromagnetic effects.

11. The device under item 8, characterized in that the unit performance and maintain the programmed parameters and modes of action contains directional current pulses connected to the output amplifier, and the electromagnetic coil of the inductor divided into groups, each of which is directly connected to the output amplifier.

12. Device for electromagnetic effects on living tissue, comprising a generator and an electromagnetic inductor acting on a biological object, wherein the electromagnetic coil configured to generate a homogeneous field, inducing currents with pulse frequency of the bell-shaped form of 0.6 to 3.0 Hz and with a pulse frequency sinusoidal 8,0 - 15,0 Hz, intensity of 0.5 to 5.0 MT, while it contains a block of programming parameters of the created electromagnetic field and modes of its effects on tissues and unit performance and maintain the programmed parameters and modes.

14. The device according to p. 12, characterized in that it further comprises a display unit response indicators of blood flow in the vascular network of the tissue to electromagnetic effects.

15. The device according to PP.12 and 13, characterized in that the unit performance and maintain the programmed parameters and modes of action contains directional current pulses connected to the output amplifier, and the electromagnetic coil of the inductor divided into groups, each of which is directly connected to the output amplifier.