IPC classes for russian patent Method for formation of two-dimensional liner electric field and device for its implementation (RU 2496178):
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Method of separating ions of organic and bioorganic compounds in ion rotation-averaged electric field of sectioned cylindrical cell / 2474917
Basis of the invention is separation of ions from external source according to the mass-to-charge ratio (m/z) in a mass spectrometer with an orbital ion trap without a centre electrode, where a longitudinal ion rotation-averaged electric field which is close to harmonic is formed by applying suitable potential across sections of the surface of the trap. Rotation of the analysed ions is excited when these ions are fed into the cell along its axis by a rotating electric field. Loss of ions on the wall of the cell is prevented by applying an effective potential which arises when ions pass near the surface with alternative potential on its sections. Detection of induced signals from oscillating ions is carried out when the rotating field is turned off, and processing of said signals for relatively wide ranges of m/z is carried out based on fast Fourier transformation. For the selected intervals of m/z, the registered data are approximated with exponentially damped sinusoidal curves whose frequencies characterise m/z of ions, and indices of the damped exponential characterise the average frequency of collision of the analysed ions with atoms and molecules of residual gases. Axial input of ions into the cell enables their accumulation, dissociation, energy analysis and separation according to mass, charge and mobility.
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Method of separating ions of organic and bioorganic compounds in supersonic gas stream, pre-detection and conveyance of said ions into subsequent mass analyser / 2474916
Invention relates to separation of ions in a linear radio frequency trap with a gas stream along the axis of said trap based on differences of said ions in appearance energies, mass, charge, mobility, capture cross-sections of slow electrons and metastable excited particles, as well as in efficiency of formation by recharging on ions of a buffer gas when said ions are exposed to alternating and constant electric fields formed inside the trap, including by charges of ions with relatively low m/z, focused around the axis of the trap. In necessary cases, the ions can be additionally separated according to resistance to collision-induced dissociation. The invention is characterised by orthogonal interfacing of the linear radio frequency trap with the subsequent mass analyser using a double-grid electrostatic mirror and pre-detection of ions reflected by said mirror and which do not fall into the mass analyser.
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Ion mobility spectrometers / 2474915
Device has reaction region separated from drift region by electrostatic gate. Doping material is fed into reaction region from doping circuit while drift region is not alloyed. Two ion modifiers to create strong field are arranged in drift region, one after another. One modifier to remove alloying adducts from ions or both modifiers may be used to subject ions to fragmentation.
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Source of ionisation based on barrier discharge / 2472246
In a device for generation of ions, comprising an ionising chamber, including the first electrode, the second electrode arranged opposite to it, and a dielectric element installed between the first and second electrodes and tightly adjacent to the working surface of the first electrode, and also a source of high voltage, according to a utility model, the second electrode is arranged in the form of a metal cap, covering the dielectric element with the first electrode installed on it, besides, the bottom of the second electrode is arranged in the form of a grid, covered with a thin dielectric layer coated at both sides, the area of the working surface of the first electrode is commensurate to the maximum to the area of the grid of the second electrode, and the dielectric element is arranged in the form of the cap and is installed inside the second electrode.
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Method of separating ions of organic and bioorganic compounds based on ion mobility increment and transportation of said ions inside supersonic gas stream / 2468464
Basis of the invention is separating ions from an external source in an ion mobility increment spectrometer (IMIS) with a cylindrical symmetrical shape with a partitioned external electrode, where independently varying dispersion voltage and compensating voltage is applied across sections. These voltages facilitate focusing of the desired ions in the initial section of the drift channel near the middle of the analytical interval of the IMIS, their controlled shift to the outer surface of the external electrode in the middle part of the drift channel and controlled shift to the central electrode in the final part of the drift channel. This enables to primarily transmit desired ions with offset from impurity ions due to their probable dying at electrodes of the IMIS. Surviving ions, under the action of the electric field and a small portion of the gas stream entering the capillary which forms a supersonic gas stream, drift into that capillary and inside the supersonic gas stream coming out of that capillary and enter into the next mass analyser. Separation of signals from all ions focused inside the IMIS is possible based on detecting two-dimensional or four-dimensional distribution of flux density of the detected ions when scanning voltages which shift ions to electrodes of the IMIS.
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Apparatus for manipulating charged particles / 2465679
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Method of analysing charged particles based on energy mass and apparatus for realising said method / 2459310
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Multichannel detection / 2451363
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Method of igniting corona discharge in ion source of ion mobility spectrometer / 2439738
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Devices and methods of diagnostics with application of ionic probes demonstrating photone-avalanche effect / 2435516
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Device for production and analysis of analyte ions / 2346354
Invention relates to analytical instrumentation, in particular, to detection of ultratraces of hazardous substances - explosives, drugs, toxic substances. Technical effect is achieved as follows: device comprises a drift tube connected to the sample introduction device, which comprises a casing with nozzles for sample input and for gas bleeding from ionisation zone. The casing comprises a reciprocable target with nanostructured surface; continuously operating blower is positioned along the inlet and outlet nozzles axis; at the opposite inner end of the drift tube there is a collector connected to an amplifier; the amplifier output is connected to computer input. The target is provided with temperature controlling assembly.
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Ion mobility spectrometre / 2390069
Ion mobility spectrometre has an ion formation chamber, an ion source, a drift tube with a collector and an aperture element which form an ejection region, an ejection electrode and an ion valve, a drift gas inlet into the drift region. The power system of the ion source has an ioniser housing with an axially symmetric shape. On the walls of the ioniser housing there are radially directed inlet devices and devices for ionising samples of the analysed substance. The point of intersection of the axes of inlet devices lies opposite the top of the aperture element which is made in form of convex wall with an ion inlet opening at its top. The collector is detachable. The aperture element is made in form of a hemisphere or cone.
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Quadrupole mass spectrometre / 2391740
Quadrupole mass spectrometre has an ion source, a quadrupole mass analyser which includes four field-forming electrodes in form of circular and hyperbolic cylinders lying in parallel and symmetrically about the central axis of the analyser, and an ion collector. Each of the field-forming electrodes of the analyser has a through slotted opening on the side of its input, parallel to the axis of the analyser and lying in its plane of symmetry. The beginning of each of the openings lies at a distance of (0.5-4.0)r0 from the input faces of the analyser. The length of the opening along the axis inside the analyser is equal to (2.0-5.0)r0 and the width of the opening is equal to (0.2-0.8)r0, where r0 is minimum distance from the axis of the mass spectrometre to each of the said field-forming electrodes of the analyser.
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Method and filter to entrap contaminating effluents / 2406560
Invention relates to filtration of fluids and can be used for separating components of said fluids. Proposed method consists in applying homogeneous magnetic or electric field to produce Stark effect and, then, applying electric field oscillating in resonance with separation of energy levels caused by said Stark effect, or applying magnetic field oscillating in resonance with separation of energy levels caused by Zeeman effect. Molecules involved in resonance are caught on filter and, then removed by suction system.
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Method for structural chemical analysis of organic and bioorganic compounds while separating ions of said compounds in supersonic gas stream directed along linear radio-frequency trap / 2420826
Invention is based on separation of ions in a linear radio-frequency trap in a gas stream near the axis of said trap based on differences in mass, charge and mobility of ions when said ions are exposed to alternating and constant electric fields, created inside the trap, including charges of ions with relatively small m/z, focused around the axis of the trap, wherein ions can further be separated based on degree of resistance to collision-induced dissociation. The disclosed method involves detection of directed signals from rotating or oscillating ions derived from the gas stream by volume charge relative small ions or a non-resonance rotating field and also under the effect of fields, close on resonant on frequency, which excite harmonic motion of ions with selected m/z values. Recording of mass-spectra of product ions during collision-induced dissociation can also be carried out using a mass analyser interfaced with the trap, particularly time-of-flight mass analyser with an orthogonal ion input.
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Devices and methods of diagnostics with application of ionic probes demonstrating photone-avalanche effect / 2435516
Invention relates to devices and methods with increased sensitivity in carrying out diagnostics, for instance, optic biopsy. Method of determining area of interest includes providing one or more ionic probes suitable for demonstration of avalanche effect with shift of emitted irradiation to higher frequency, impact on ionic probe(s) by activation energy and determination of one or more areas with higher concentration of ionic probe(s) on the basis of emission, connected, at least, partially with avalanche effect. System ensures determination of area of interest in accordance with the method.
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Method of igniting corona discharge in ion source of ion mobility spectrometer / 2439738
Method is based on use of a pulsed source of corona discharge, having not less one pair of ignitor electrodes, a high-voltage pulsed generator for igniting corona discharge and a pulsed electric field generator in the ionisation region. Before at least on voltage pulse generated at the ignitor electrodes in the basic ionisation phase, at least one additional voltage pulse is generated at the ignitor electrodes, during which electric field intensity in the ionisation region has a value which is lower than the normal level or equal to zero, and at the moment of transmitting to ignitor electrodes one or a series of voltage pulses of the basic ionisation phase, electric field strength in the ionisation region is set at nominal level, thus modulating the field during ignition.
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Multichannel detection / 2451363
Detecting apparatus detects a first part of a beam of charged particles and generates a first output signal based on intensity of the detected first part of the beam of charged particles. The detecting apparatus detects a second part of the beam of charged particles which has traversed a longer trajectory section through a mass-spectrometer than the first part of the beam of charged particles, and generates a second output signal based on the detected second part of the beam of charged particles. A controller controls parameters of the beam of charged particles and (or) detecting apparatus based on the first output signal of the detecting apparatus, so as to control the second output signal of the detecting apparatus.
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Method of analysing charged particles based on energy mass and apparatus for realising said method / 2459310
Analysis based on energy and mass is carried out in superimposed radial electric field of a Hughes-Rozhansky energy analyser and the magnetic field if a Wien filter and the longitudinal electric field of the Wien filter which lies across said two fields. The Hughes-Rozhansky energy analyser and the Wien filter are merged in a single structure, the Wien filter being cylindrical. The ion detector and the distance between cylindrical plates are determined by focusing conditions of the target ions.
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FIELD: electricity.
SUBSTANCE: method for formation of two-dimensional linear electric fields consists in formation of one coordinate of potential average value distribution per working area border using device from flat discrete and hyperbolic electrodes. Flat discrete electrodes consist of thin earthed metal fibres evenly arranged on area borders, and hyperbolic electrodes singly arranged in each quadrant have small sizes of half-axes. Under impact of opposite potentials on adjacent hyperbolic electrodes in planes of discrete electrodes there formed are linear per each axis of potential average value distribution, under their impact in working area there formed is two-dimension linear field.
EFFECT: minimising sizes and improving design-process parameters of electrode systems for formation of two-dimension linear electric fields with working areas expanded along one axis.
2 dwg
The invention relates to the fields of electron-ion optics and mass spectrometry, based on the motion of charged particles in static and variable two-dimensional linear electric fields, and can be used to improve design and manufacturing technology devices spatio-temporal focusing and mass separation of charged particles. Hyperbolic electrode system is not effective for building mass analyzers with extended along one axis working area because of the considerable size of the electrodes on all the coordinates [1]. The task system of flat electrodes with discrete-linear potential distribution [2], with discrete-varying electric transparency [3] and discrete-variable charge density [4]. The technical problem of the invention is to improve the structural and technological characteristics of the devices of formation of two-dimensional linear electric fields extended along one axis working area, using hyperbolic and flat discrete equipotential electrodes.
Two-dimensional linear electric field in the workspace size 2xc, 2ycL X, Y, Z under the condition yc>>xcyou can form using discrete flat surfaces of requirementsall routashi elements, distributed along the Y-axis with a constant step ∆y [2] or equipotential conductive elements are unevenly distributed along the Y-axis [3, 4]. Closest to the claimed solution is the method described in [4], which consists in the formation of linear electric field using equipotential elements are unevenly distributed along the axis Y. However, the disadvantages of these systems is the difficulty of design and technological nature, which would complicate the manufacturing process of the ion-optical devices and analyzers ions using a flat discrete electrodes.
In all cases when using the flat of discrete electrodes education two-dimensional linear in the XOY-plane electric fields is to create at region boundaries x=±xclinear along the Y-axis distributions of the average potential values:
where φ∂i(y) is the potential distribution in the planes x=±xcthe i-th discrete element, ∆yi- step discrete electrodes, φMCP=φcf(yc).
For the practical implementation of the ion-optical systems with two-dimensional linear electric fields are of interest, the use of discrete flat surfaces formed from uniformly distributed along the Y-axis with a step of ∆y, parallel to the Z axis, the same equipotential conductive elements (strands or strips. However, using only discrete flat with a constant step ∆y equipotential surfaces does not solve the problem of the formation of two-dimensional linear electric fields. The problem is solved by using the additional 4 hyperbolic potential surfaces, allowing you to create the linear Y-axis distribution of the average value of the potential in the planes x=±xcdiscrete surfaces. Hyperbolic surface 2 is placed in the region |x|>xcand on the adjacent surfaces establish the opposite potentials φ 0and-φ0(Figure 1). The presence of discrete surfaces 1 allows to displace the origin of the hyperbolic surfaces 2 on the X-axis at a distance x0for surfaces in the I and IV quadrants and the distance x0for surfaces in the II and III quadrants and thereby substantially reduce the value of their geometrical parameter r0- valid axis of hyperbole. The offset value is determined by the ratio:
Hyperbolic surfaces in this case are described by the equation:
Under the action of opposite potentials φ0and-φ0on related hyperbolic surfaces in the cross sections x=±xcformed potential distribution φ(±xc,y) - (curve 1, Figure 2), average values for which φcf(±xc,y) if condition (2)will change the Xia linearly (curve 2, Figure 2):
where. In workspace |x|<xc, |y|<ycformed field potential distribution of the form:
which corresponds to the two-dimensional linear electric field with the projections of the field strength on the axis X and Y:
From (5) and (6) it follows that the system of 2 flat with a constant step ∆y equipotential discrete and 4 hyperbolic surfaces allows to form a two-dimensional linear electric field in workspaces 4 |x|<xc, |yc|<y with an arbitrary value of xc, yc. Moreover, when the fixed length of the semiaxes r0hyperbolic surfaces the choice of parameters xcand ∆y are the dimensions of the stage along the X-axis can vary within wide limits.
Device for the formation of two-dimensional linear electric field on the proposed in claim 1 of the formula of the invention the method consists of 2 flat discrete electrodes 1 L>>2xcand 4 hyperbolic electrodes 2 L>>2xc(Figure 1). Discrete electrodes 1 with the size of ya>>xcon the Y-axis are located in the planes x=±xcand formed from uniformly distributed along the Y-axis with a step of ∆y thin diameter d<<∆y parallel to the axis Z of the equipotential threads. The origin of the hyperbolic electrodes are shifted in pairs on the X-axis at a distance of ±x0and have the final coordinates x=±xay=±yawhere xa≥(xc+1.50), ya≥(yc+1.5xc). Hyperbolic electrodes are located outside of the RA the eyes region 4 (figure 1) |x|> xcone in each quadrant. Geometric parameter r0hyperbolic electrodes is determined by the step discontinuity ∆y flat electrodes and their size yaaxis Y:
.
For the given parameters xc, ycworkspace geometric parameter r0hyperbolic electrodes used in conjunction with discrete flat electrodes with a constant step value ∆y, is significantly less than the parameter r0hyperbolic electrodes 3 (Fig 1)that generates the same field in the absence of discrete electrodes. This allows the analyzer elongated along the Y-axis workspaces 4 (figure 1), when yc>>xcby minimizing the value of the parameter r0hyperbolic electrodes in 2-2,5 times to reduce the size of the electrode systems of analyzers on x-axis Dimension L of the electrodes 1 and 2 along the Z axis is chosen based on the acceptable level of deviation of the field from the line in the workspace of the analyzer due to edge effects:
L≥4xc.
Use as a flat discrete electrodes evenly distributed along the Y-axis metal thread in conjunction with hyperbolic electrodes. the em design and manufacturing technology, and also reduces the size analyzers with two-dimensional linear electric fields.
LITERATURE
1. Gurov B.C., Mammoths E.V., Diaghilev A.A. Electrode system with a discrete linear distribution of high frequency potential for mass analyzers charged particles // Mass spectrometry. 2007. No. 4 (2). - S-142.
2. Patent RU No. 2327245 from 03.05.2006, the Way mass-selective analysis of ions by time-of-flight and device for its implementation.
3. Patent RU No. 2387043 from 10.04.2008, the Method of forming the linear field and a device for its implementation.
4. Patent RU No. 2422939 from 25.11.2009, the Method of forming a two-dimensional linear electric field and the device for its implementation.
1. The method of forming a two-dimensional linear electric field, which consists in creating the boundaries x=±xcworkspace |x|<xc, |y|<ycparallel to the axis Z plane discrete conductive surfaces with sizes 2yaL Y, Z, composed by distributed along the Y-axis parallel to the Z-axis of the thin conductive filaments, wherein the Y-axis equipotential threads evenly distributed increments Δy, and the edges of the stage |x|>xchave one in each quadrant of the hyperbolic conductive surfacewhere |x0|<|xc|, r0- the real axis of hyperbole, and on the adjacent surfaces set opposite potentials φ0and-φ0.
2. Device for the formation of two-dimensional linear electric field that contains the edges of the stage x=±xcparallel to the Z axis electrodes of length L>>2xcfrom distributed along the Y-axis parallel to the Z-axis conductive thin filaments, characterized in that use two in the planes x=±xcdiscrete size ya>>xcon the Y-axis electrode of evenly spaced increments Δy along the Y-axis equipotential threads with a diameter of d<<Δy and four, one in each quadrant, hyperbolic electrode with a valid radius r0shifted in pairs on the X-axis at a distance of ±x0with a final coordinates x=±xa,
y=±yawhere xa≥(xc+1,5r0), ya≥(yc+1,5xc).
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