Method of treating visceras

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to methods of treating diseases of various aetiologies and injuries of various visceras. Electropunctural pre-examination aims at determining the patient's overall potential and the potential in a point on the body surface at a minimal distance from the viscera to be treated, or in its immediate projection tender zones. A stem cell growth area is stimulated by placing a bee within the sternum. Then, an irritation centre is created using vacuum- or hirudotherapy in a point on the body surface at a minimal distance from the above viscera or in its immediate projection tender zones. The irritation centre is created to be intensive and short-term at the level of the potential in the point below the overall potential, or to be weak and long-term at the level of the potential in a point above the overall potential.

EFFECT: method provides the effective local therapeutic effect on the involved visceral tissues ensured by a combination of the used components of the effect.

2 cl, 3 ex

 

The invention relates to medicine, namely to methods of treatment of different diseases and injuries of various organs.

There is a method of treatment of different diseases and injuries of various organs using mesenchymal stem cells (MSCS) or their differentiated progeny (see patent RU 2301667, IPC A61K 31/195, A61K 35/28, A61P 43/00). MSC injected in cultures derived from autologous or neautrogena human tissue, intravenously or directly into the affected organ or on its surface. After this the patient intramuscularly or on the skin surface impose drug metaprogram or its chemical analogue: 2-(3'-dimethylaminopropyl)-5-methylhexan-4-OIC acid or 2-(3'-dimethylaminopropyl)-5,9,13-trimethylacetamido-4,8,12-OIC acid. The method provides an improvement of results of treatment by accelerating the healing process, even when using minimal doses of metoprolol or its counterpart, the gain distribution in the affected tissues intensively proliferating cells.

However, in this method, the stem cells are injected invasive, which can lead to immune response.

There is a method of treatment of traumatic lesions of the spinal cord, applicable in neurosurgery for the treatment and rehabilitation of patients with persistent neurological defic the volume after trauma to the spinal cord (see the patent RU 2286160, IPC A61K 35/28, A61P 25/00). The method includes the transplantation of bone marrow stem cells, which use of autologous mononuclear bone marrow cells of the patient. After 24-hour incubation, the cells are divided into two factions. The fraction of cells adherent to plastic injected into the cavity emptied intramedullary cysts in the amount not exceeding the size of the cavity of the cyst, and the fraction of cells adherent to plastic, is injected. The method can reduce the severity of neurological deficits in patients in remote and late period of traumatic disease of the spinal cord due to the complex influence on the repair of nervous tissue of all types of stem cells, which differentiate into neuronal direction directly in the body of the patient without prolonged cultivation in vitro.

However, this method involves a long procedure incubation of cells; and besides, he has all of the disadvantages associated with the introduction of invasive cells.

Known biotransplant and method for the treatment of parkinsonism (see patent RU 2259836, IPC A61K 35/30, A61K 35/48, A61P 25/16). Biotransplant for the treatment of parkinsonism contains the active ingredient: the culture of genetically unmodified neuronal stem cells (NSC)derived from the forebrain tissue is of human embryos in the 1st trimester of pregnancy or periventricular areas of the brain 15 to 20 weeks of gestation and selectively propagated in culture conditions to the number 107-109 pluripotent undifferentiated cells as part of neurostar, when the content of the CLAIM 50-500 million, and 2 ml of physiological solution. A method of treating Parkinson's disease include the introduction of the patient endolyumbalno 50-500 million NSC in 2 ml of physiological solution, simultaneously. The proposed biotransplant and a method of treating parkinsonism quickly to restore and improve function of affected brain and reduce the duration of treatment, and also provides a more stable and long-lasting effect.

However, in this method using human embryos, which is contrary to the norms of humanity and morality.

The closest is a method of targeted delivery of stem cells in the treatment of optic nerve atrophy of various etiologies (see patent RU 2375019, IPC A61F 9/007, A61K 35/28, A61P 27/02). Spend vitrectomy, remove the back of the hyaloid membrane, with the nasal side of the optic nerve perform radial optical neurotomy (RON). Conducting radial optical neurotomy from the nasal side of the optic nerve creates a depot for targeted delivery of mesenchymal stem cells in the optic nerve and improves volumetric blood flow velocity in the optic nerve in the dissection of the laminar plates and expansion of the scleral canal, the occurrence of chorioretinal anastomoses in the postoperative period. Immediately after RO is formed in the channel administered 0.05 ml of autologous cultured mesenchymal stem cells from bone marrow of the patient. Intravitreal (into the vitreal cavity of the eye) injection of autologous cultured MSC bone marrow of the patient in the channel RON accompanied by their selective adhesion in this area, which contributes to the activation of reparative processes due to engraftment of transplanted stem cells in the damaged areas with the consequent proliferation and differentiation of both transplanted and resident stem cells.

The disadvantage of this method is the necessity of surgical intervention in the patient, the complexity of the procedure, including the cultivation of autologous stem cells in vitro, as well as the lack of control the relationship between the body's need for stem cells and the amount introduced into the body cells.

The task of the claimed invention is to provide selective therapeutic effects.

The technical result is to increase the effectiveness of treatment by providing a local therapeutic effect.

This technical result is achieved by the fact that, according to the claimed method of treatment, pre-electroacupuncture at the examination determine the overall potential of the body of the patient and the potential at a point on the body surface at a minimum distance from the body requiring treatment, or is it the nearest flat area Zakharyin-Ged on the skin, stimulate the growth zone of the stem cells according to the method Muzalevskaya by raising bees in the sternum, and then create a focus of irritation with the use of vacuum or occupational therapy at a point on the body surface at a minimum distance from the specified authority or its nearest projection area Zakharyin-Ged on the skin, while the focus of intense irritation and transient when the level of the potential at a point below the total capacity, or weak and long at the level of the potential at a point higher than the common potential. Pre spasms and improve blood flow to the tissues of the body requiring treatment.

The inventive method includes the following procedures.

1. Diagnosis the delivery of stem cells.

Carry out diagnosis of the body, measuring the potentials at the test points according to the method Muzalevskaya (RF patent for the invention №2177776). First, determine the total capacity of the patient's body by measuring the conductivity (or electrical resistance) by any known method or device designed for electric diagnostics by R. Voll, for example, with industrial output device "VEDA-903": "Electro-diagnostic apparatus of the General practitioner, homeopath and family doctor". This indicator is cleared when the electro-examination iyavlyaetsya assessment criterion for further diagnostics (see Passport, technical description and operating instructions "VEDA-903", p.18). By registering readings when the connection is connected to the device of the active electrode with the palm of the left hand of the patient, and a passive electrode, with the palm of the right hand determine the average values of the total conductivity of a man (the total capacity of the body), which are within 78-82 dimensionless units. Next, perform a measurement of potentials in the individual control points located on the body surface at a minimum distance from the body (target)requiring treatment or in its immediate projection area Zakharyin-Ged on the skin. The potential is measured by connecting the active electrode with the control point.

If necessary, provide training to the treatment of body tissues in the delivery of stem cells. Typically, unhealthy body is in shock, spasm, so after it is identified, conduct preparatory therapy to relieve spasms and normalization of blood flow through the body. Examples preparatory therapy can be massage, finger, objavljivanje, drug withdrawal spasms, in addition to antispasmodic action have procedures vacuum and hirudotherapy.

2. Stimulation of the production of stem cells in the human body

To stimulate the production and in the human body necessary for tissue repair in the number of stem cells are leeching or apitherapy the chest on the way Muzalevskaya (RF patent for the invention №2417052). Reflex effects of exercise on the area of the sternum using gerudo and/or apitherapy. Prior to exposure to carry out measurement and calculation of the averaged potential of the front part of the body except for the area of the sternum, namely at the points of small pelvis in the center, right, left, in place of the projection above the kidney, liver, stomach, pancreas, gall bladder. Separately provide measurements of the potential area of the sternum in the points situated on the middle line in the center arm of the sternum, at the level of the fourth rib of the body of the sternum and in the area of the xiphoid process. Then reveal the variation of potential in the area of the sternum from the average values of potential the front, and identifying reduction potential values of the area of the sternum relative to the averaged value of the potential of the front part of the body carry the impact of a leech or a bee on the sternum area not more than 3 minutes with a control measurement of potentials. The effect is repeated until the alignment of the values of the potentials or exceeding the value of the potential of the sternum above the average value of the potential of the front part of the body. When implementing the method using no more than 5 leeches on 1 session or 1-3 bees, leaving the stinger in the time from 20 seconds to 3 minutes. The number of repeated impacts depends on the condition of the patient.

3. And the targeted delivery of stem cells.

When focusing the impact of stem cells on the body (target), characterized by a control point with the value of a potential lower than the total capacity of the patient, at this point create foci of irritation by short-term (up to three minutes)but intense vacuum or hirudotherapy. When focusing effects on the body, the potential value of the corresponding point which is higher than the common potential of the patient, at this point create foci of irritation by prolonged (three to thirty minutes), but a weak vacuum or occupational therapy. Irritation helps to increase blood flow and microcirculation in the field of application of therapeutic effects, and establishing targets for attracting produced in the body's stem cells to the affected area. Thus, it is possible to achieve maximum local concentration of intrinsic stem cells of the patient in therapeutic effect and, accordingly, high restorative effect of damaged organs from the effects of stem cells.

Industrial applicability with the achievement of the technical result of the claimed invention is illustrated by the following examples of clinical trials.

Example 1. The patient LWP, 59 years old.

In June 2011 pproviding ultrasound of internal organs. The diagnosis of hepatomegaly, fatty infiltration p is Chaney (point form) chronic cholecystitis (stagnant bile), chronic pancreatitis (microcavities), minor venous congestion of the kidneys. Conducted stimulation zone growth of stem cells apitherapy with a focus on the region of the liver and kidneys vacuum therapy and leeching - conducted 5 sessions a day. For the selection of exposure modes previously conducted measurements of biopotentials in the areas of production of cans and leeches method Muzalevskaya. On the edge of the costal arch to the right potentials were increased, so the effect was implemented to reduce potential weak excitation lasting more than ten minutes (on brake method). In the kidneys from behind potentials have been reduced, so the effect was implemented for capacity building - strong excitation with duration of up to three minutes (according to the method of excitation).

The 1st session. To encourage the patient's stem cells held apitherapy - one bee was placed in the region of the sternum to the point with the lowest potential for thirty seconds. To focus the impact of stem cells on liver spent occupational therapy five leeches on the edge of the costal arch to the right before saturation. To focus the impact of stem cells on the kidneys spent vacuum-therapy - using two cans (one Bank for each kidney) execute and strong impact on the kidneys back within three minutes.

The 2nd session. Stimulate the body's production of the patient's stem cells at the first session. To focus the impact of stem cells on liver spent vacuum-therapy - with three cans made little impact on the edge of the costal arch to the right for more than ten minutes. To focus the impact of stem cells on the kidneys spent hirudotherapy - two leeches on two sides on the kidneys back within three minutes.

3rd session. Stimulate the body's production of the patient's stem cells at the first session. To focus the impact of stem cells on liver spent vacuum-therapy - with three cans made little impact on the edge of the costal arch to the right for more than ten to twelve minutes. To focus the impact of stem cells on the kidneys spent vacuum-therapy - using two cans (one Bank for each kidney) made a strong impact on the kidneys back within three minutes.

4th session. The same as in the first session.

5th session. Same as in the second session.

After two months of repeated ultrasound. Diagnosis: chronic cholecystitis in remission, chronic pancreatitis, kidney pathologies it is not revealed. Thus, there are clear signs of improvement of ultrasound data. Feeling patsie the TA has improved.

Example 2. The patient VBA, 56.

Diagnosis: benign prostatic hyperplasia 1-2 degrees on the background of calculous prostatitis. In 2009, the stimulation of the growth zone stem cells without focusing effects of stem cells on delivery. There is General improvement, has improved the condition of internal organs. Changes of the prostate were observed. In 2010, held three sessions of stimulation zone growth of stem cells with a focus on the impact of stem cells on the prostate gland.

The 1st session. Stimulate the body's production of the patient's stem cells, which held apitherapy - two bees per minute in the sternum area. To focus the impact of stem cells on the prostate gland spent vacuum-therapy - severe agitation up to three minutes in the sacrum and in the suprapubic area, as well as leeching four leeches on the coccyx and three leeches PA crotch before saturation.

The 2nd session. Stimulate the body's production of the patient's stem cells at the first session. To focus the impact of stem cells on the prostate gland spent hirudotherapy - four leeches in the rectal area before saturation, and vacuum-therapy - severe agitation up to three minutes in the suprapubic area.

3rd session. Stimulated production is in the patient's stem cells at the first session. To focus the impact of stem cells on the prostate gland spent hirudotherapy three leeches in the suprapubic area to saturation, as well as vacuum-therapy - weak agitation for ten minutes in the rump.

Repeated ultrasound control after 5 months showed decrease swelling of the prostate gland, a significant positive trend; hyperplasia of 1 degree.

Example 3. The patient BNW, 60.

The diagnosis of hepatomegaly, moderate diffuse changes of the liver parenchyma (lipomatosis steatosis), chronic cholecystitis (Zamoskvoretskaya bile), chronic pancreatitis, diffuse changes in the pancreas.

The 1st session. Stimulate the body's production of the patient's stem cells, which held apitherapy - one bee was placed in the sternum area for thirty seconds. To focus the impact of stem cells on liver spent hirudotherapy - five leeches on the edge of the costal arch to the right before saturation.

The 2nd session. Stimulate the body's production of the patient's stem cells, which held apitherapy - one bee was placed in the sternum area for two minutes. To focus the impact of stem cells on the pancreas spent hirudotherapy three leeches to saturation at the surface of the body in the area of the projection of the pancreas.

3rd session. Stimulated exp is processing the patient's stem cells, what held apitherapy - two bees were placed in the sternum area for two minutes. To focus the impact of stem cells on liver spent hirudotherapy three leeches on the edge of the costal arch to the right before saturation. To focus the impact of stem cells on the pancreas spent hirudotherapy two leeches before saturation on the surface of the body in the area of the projection of the pancreas.

After four and a half months in the ultrasound revealed signs of chronic congestive cholecystitis, chronic pancreatitis. A significant positive trend.

1. The method of treatment of internal organs, wherein the pre when electro-examination determine the overall potential of the body of the patient and the potential at a point on the body surface at a minimum distance from the body requiring treatment, or in its immediate projection area Zakharyin-Ged on the skin, stimulate the growth zone of the stem cells according to the method Muzalevskaya by raising bees in the sternum, and then create a focus of irritation with the use of vacuum or hirudotherapy at a point on the body surface at a minimum distance from the specified authority or its nearest projection area Zakharyin-Ged on the skin, when this is the focus of intense irritation and kratkofil the config when the potential level at the point of common potential or weak and long at the level of the potential at a point higher than the common potential.

2. The method according to claim 1, wherein the pre spasms and improve blood flow to the tissues of the body requiring treatment.



 

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