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Controlled degradation of structured polyribonucleotides. RU patent 2458986.

FIELD: chemistry.

SUBSTANCE: structured polyribonucleotides undergo degradation through incubation of a sample containing them with thermally stable polynucleotide phosphorylase (PNPhase) Thermus thermophilus in the presence of a co-substrate and a cofactor.

EFFECT: invention enables to conduct enzymatic phosphorolysis of RNA at high temperature.

7 cl, 20 dwg

IPC classes for russian patent Controlled degradation of structured polyribonucleotides. RU patent 2458986. (RU 2458986):

C12N9/22 - Ribonucleases

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