Method of treatment and prevention of gastroenteric disorders at animals

IPC classes for russian patent Method of treatment and prevention of gastroenteric disorders at animals (RU 2343942):

A61N5/02 - using microwaves (A61N0005010000 takes precedence);;

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FIELD: medicine; veterinary science.

SUBSTANCE: electromagnetic radiation of EHF range on frequencies of 65 GHz either 129 GHz or 300 GHz consistently influence on stomach BAT, cholic bubble and rectum during 1-2 mines on each area daily.

EFFECT: ecologically safe nonmedicamentous treatment of entero-gastric diseases of animals, rising of efficiency and reduction of terms of treatment.

7 tbl, 3 ex

The invention relates to the field of veterinary medicine and can be used for treatment of gastrointestinal disorders in animals, such as dyspepsia, diarrhea, gastroenteritis.

Known medicinal solutions, preparations, mixtures and structures used for treating dyspepsia, containing antimicrobial drugs, minerals, vitamins, protein preparations, etc. used in various ways.

There is a method of treatment of dyspepsia young farm animals, which includes the introduction of the drug spirit and honey extract walnuts milky-wax ripeness with the addition of pollen and glycine together with portions of the liquid dose 2 times a day for 6 days at 0.5 ml per 1 kg of weight of animal. Application of the extract increases the effectiveness of treatment, reduces its duration (see RF patent № 2276989, IPC A61K 36/00).

There is a method of treatment and prevention of dyspepsia calves and piglets, according to which conduct the introduction of antibiotics, with 6.0 g of formazine and 100 mg of sodium Selenite was dissolved in 100 ml of distilled water and injected at 0.5 to 6 ml intramuscularly 1 time per day 2 times per treatment, while inside are 5-15 ml of sunflower oil with the addition of 50-100 mg of zinc sulfate (see RF patent for the invention № 2229883, IPC A61K 31/435).

There is a method of prevention and treatment of dispepsi the farm animals and poultry (prototype). The essence of the invention is the holding group for aerosol treatment of animals and poultry 0.1 to 0.15%electrolysis of the sodium hypochlorite solution in amounts of 5-10 ml/m³with exposure 30-40 min 1, 3, 7, 10, 14, 20, 30, 40 and 50 days with simultaneous addition in drinking water is 0.3-0.5% sodium hypochlorite in the ratio of 1:150-1:200 in the first period of 14-28 days of their detention. The positive effect of the application of the method can improve the safety of the birds to 98.4%, while in the control groups, this indicator equaled 94,0%. At the same time using the method of young cattle allows you to achieve 100% preservation of animals, while in the control group, this indicator was equal to 70.0% of (see RF patent for the invention №2054291, IPC A61K 33/14).

However, medical methods are often ineffective or have side effects, for example, when the antibiotics killed the useful microflora.

The task of the technical solution is the creation of environmentally safe non-drug method of treatment of gastrointestinal diseases of animals while improving the efficiency and reducing treatment time.

The problem is solved in that in the method of treatment and prevention of gastrointestinal disorders in animals according to the invention sequentially exposed to electromagnetic who itim radiation EHF at BAT of the stomach, gall bladder and rectum within 1-2 minutes on each area daily for 5-7 days at frequencies of molecular spectrum of atmospheric oxygen, in particular 65 GHz, or 129 GHz and 300 GHz.

The method is as follows. The effects of electromagnetic radiation of millimeter range operate at the resonant frequencies of molecular absorption spectrum and emission of atmospheric oxygen. The impact of exercise on the BATH of the stomach, gall bladder and rectum within 1-2 minutes on each area on a daily basis. Irradiation is carried out at frequencies of 65 GHz or 129 or 300 GHz, for example, using short-wave generator - panoramic-spectrometric complex with the quasi-optical reflectometer operating in the frequency range 118-600 GHz or apparatus "Universal-M at a frequency of 65 GHz.

The choice of frequency of exposure due to the fact that at these frequencies causes the activation of the secretory activity of the stomach, which contributes to more complete digestion of food, oppressed conditionally pathogenic microflora and increases lipid peroxidation conducive to the normalization of inflammatory processes of the digestive tube that was installed by us experimentally.

Table 1.
Efficiency the efficiency of therapy of gastrointestinal disorders in animals, depending on exposure time and frequency EMR UHF mm range, %
Qty animals	the exposure time, min	65 GHz	129 GHz	300 GHz
10 experience	0,5	50,0	60,0	60,0
10 experience	1,0	60,0	70,0	70,0
10 experience	2,0	80,0	90,0	90,0
10 experience	3,0	70,0	80,0	70,0

Irradiation is carried out daily until recovery of the animal, the average number of radiation sessions is 5-7, during which there is a recovery in the maximum number of animals, as seen from the table. Impact exercises once a day consecutively for all the claimed area of impact.

Example 1. In cattle.

Table 2.
Indicators scar digestion in patients calves when exposed to electromagnetic radiation (EMR) EHF frequencies of molecular spectrum of atmospheric oxygen.
Indicators	Group
before the treatment	after treatment the
pH	6,0±0,2	6,7±0,1^**
total acidity, mmol/l	78,2±1,2	82,6±1,3^*
proteoliticheskaja activity, mm	1,8±0,04	2,5±0,06^*
the amylolytic activity, mm	5,1±0,09	5,7±0,1^*
total nitrogen, mmol/l	60,4±0,9	63,6±0,7^*
residual nitrogen, mmol/l	26,8±0,8	29,7±0,6^*
protein nitrogen, mmol/l	34,7±0,9	33,9±0,8
Table 3.
Therapeutic effectiveness at frequencies of molecular spectrum of atmospheric oxygen with dyspepsia in calves.
Indicators	Therapy
traditional	offer	Normalization of the pulse, the day	4,8±0,2	4,3±0,2	3,5±0,2
The normalization of breathing, the day	4,9±0,1	2,3±0,2	3,4±0,1
Normalization of defecation, the day	4,7±0,2	2,5±0,1	3,6±0,1
Clinical recovery, the day	5,8±0,1	4,5±0,1	4,9±0,2
Therapeutic effect %	80,0	96,0	90,0

The absolute increase in live weight, kg

Table 4.
Growth dynamics in live weight of calves after treatment at a frequency of 300 GHz.
Indicators	Group
traditional	offer	prevention
Live weight at the beginning of the experience, kg	26,2±1,9	26,8±1,8	26,0±1,9
Live weight in 30 days, kg	51,5±1,7	58,2±2,2	of 56.4±2,5
20,5±0,8^*	26,2±0,7^**	24,2±0,9^*
Average daily gain, g	436±9,5	540±11,8^*	473±10,2^*

Example 2. In pigs.

td align="center"> Recovered %

Table 5.
The effect on the frequencies of molecular spectrum of atmospheric oxygen on the secretory function of the stomach of pigs.
Index	Group
to experience	after applying EMR EHF
Total acidity, % title	32,4±4,4	38,8±3,8
Related hydrochloric acid, a unit of the title	12,6±1,7	18,2±1,8^*
Free hydrochloric acid, a unit of the title	1,2±0,2	4,8±0,6^**
Table 6.
Therapeutic efficacy at different frequencies with diarrhoea in piglets
Group	Forcibly killed, %	No effect, %	The duration of treatment, days
traditional therapy	80,0	5,0	15	6,2±0,2
Experience 65 GHz	96,0	-	4,0	4,3±0,3^*
Experience 129 GHz	96,5	-	3,5	3,7±0,1^*
Experience 300 GHz	97	-	3	3,9±0,2^*

Example 3. Dogs.

Table 7.
Therapeutic efficacy at different frequencies with gastroenteritis in dogs.
Indicators	The duration of treatment, days	Clinically recovered, %	No effect, %
Traditional therapy	14,7±1,7	53	47
Experience 65 GHz	7,2±1,9^**	70	30
Experience 129 GHz	6,9±1,7	85	15
Experience 300 GHz	7,0±1,6	80	20

Method for the treatment and prevention of gastrointestinal disorders in animals, characterized in that consistently influence of electromagnetic radiation of millimeter range at frequencies 65 GHz, or 129 GHz and 300 GHz at BAT of the stomach, gall bladder and rectum within 1-2 minutes on each area on a daily basis.