Antiperspirant and deodorant compositions

FIELD: medicine.

SUBSTANCE: invention relates to field of cosmetics. Water-free antiperspirant or deodorant composition, which contains: particle of astringent antiperspirant salt; 20-90 wt % of oil-carrier, gelling agent for oil-carrier and moisturiser-polyol, moisturiser-polyol constituting 0.1-10% in terms of composition weight, polyethylene glycol has average molecular weight to 820. Product, containing composition is in distributing vessel, which contains balloon, on one end of which there is at least one hole, through which composition can be pushed out, and on the opposite, second end there is lift, fitting internal surface of balloon and able to move to the first end. Non-therapeutic method of suppressing sweating or weakening body smell, including stage of topic application of composition on skin.

EFFECT: invention ensures good sensor properties of composition.

30 cl, 9 tbl, 27 ex, 1 dwg

The invention relates to antiperspirant or deodorant compositions and, in particular, to anhydrous compositions.

The LEVEL of TECHNOLOGY

On the market for deodorants and antiperspirants are products on the basis of knitting salts of aluminum and/or zirconium, which are designed for local alerts, or at least suppression of sweating through the skin, particularly in the armpits. By doing so, the user can prevent or at least to prevent the formation of wet spots in the armpits or on clothing that covers the arms, which in some societies is considered ugly. Controlling thus the amount of sweat on the skin surface, the user simultaneously limits the supply of organic compounds resident populations of bacteria in the skin that make such connections, bad smelling, therefore, astringent salts also act as a deodorant. Such astringent antiperspirant salts can also act as bactericidal and thus to act as a deodorant, even if they are used in quantities less than required for effective control of sweating.

There was a side effect of such binders salts, namely, they tend to dry the skin and, in particular, the stratum corneum and the skin to some extent loses its elastic the th. The advantage of overcoming this shortcoming is recognized, for example, in EP 966258.

For compositions containing astringent antiperspirant salt, which are intended for topical application to the skin, suggested many changes in the form, for example, proposed a liquid composition adapted for application by spraying; spray typically comes at the expense of the pump or propellant. Other compositions, the so-called contact formulations are designed to be rubbed into the skin and contain the carrier medium, in which are dissolved or suspended antiperspirant salt; the carrier medium is transformed into a gel (overiden, structured) with the formation of solid or semi-solid composition. Depending on the nature and composition of any liquid carrier composition and, in particular, the contact of the composition may be anhydrous or contain water.

In certain varieties, which are particularly popular in North America and available in other countries, contact the compositions are anhydrous and contain particles astringent salt suspended in the gelled, water-immiscible oil. As in other types of antiperspirant compositions, in them it is desirable to include a tool that has its own drying of the skin which is in contact with the composition. For this purpose has already been proposed to use a humidifier and frequent the spine, humidifier containing multiple hydroxyl groups; also recognized that the introduction of such a humidifier in these anhydrous compositions can lead to a problem of formation of solid particles. Although the present invention does not depend on will be whether any particular assumption, postulate, hypothesis, theory or belief is correct, polyols, apparently, able to migrate to the surface of the particles of antiperspirant salts at temperatures normally used for dispersion or dissolution of the gel in the oil-carrier, and then to act as a binder between the particles and thereby cause agglomeration of the particles. The solid particles are particularly undesirable in contact compositions, because in the best case, the user may experience an unpleasant sensation, and in the worst case, such a composition may irritate or scratch the skin. This problem can worsen the habit of the user, which is widespread in North America (and some other parts of the world) and is removed before applying the antiperspirant hair from underarms using shaving or plucking, which makes the skin more sensitive. Indeed, the skin irritation caused or reinforced by solid particles or any other source, causes the user inconvenience or pain and suppress their desire p is to Adolat to use this product or to buy it again.

The formation of solid particles can also reduce the bioactivity of the composition, by which is meant the ability of the active ingredient to perform the desired function, such as the hydration of the polyol. Again without being bound by theory, the biological activity of the polyol is reduced if the polyol before release forms a complex with antiperspirant active substance, thus, the formation of complexes may contribute to this reduction of bioactivity.

So far, it was proposed two ways of combating the problem of formation of solid particles. According to one method, described in more detail in EP 966258, the additional substance is a carrier of odorants is mixed with moisturizer, in particular glycerol, before making the final in a mixture containing antiperspirant salt. Although this method can be used, it effectively has been used since 1997, he imposes on the manufacturer to various limitations. For example, it imposes at least some restrictions on the preparation of the composition. Any additional substance included in the composition to solve the formation of solid particles, reduces the space for the other ingredients. In addition, the introduction of media odorants creates a risk of delayed release or may preclude the release of a perfuming composition of the village is e local application, thereby reducing its impact and at least the immediate bioavailability of any substance absorbed by the media.

The second way that allows at least to weaken the formation of solid particles consisting of antiperspirant salt and the humidifier during the manufacture of the anhydrous antiperspirant compositions of the pencil was proposed Reheis Inc. in USP 6649153. Reheis proposes to create complex humidifier and antiperspirant salt in obtaining salt. This idea is discussed in WO 03/070210 in the name of Unilever et al. Before was referred to the problem of formation of solid particles, complexes of antiperspirant salt and polyol were disclosed or referred to in US 3981986, EP 217012, GB1267959, GB1159685, ES 3873686, US 4089120 and US 3792070. Although the formation of complexes polyol with antiperspirant salt may resolve the problem of the formation of solid particles during the manufacture of antiperspirant compositions, the polyol must be released from the complex before will be able to provide moisture to the skin, so that after application of the composition, the polyol is not immediately available for hydration. The polyols can easily form complexes with astringent salts of aluminum and zirconium, so that the destruction of the complexes is not a quick or easy process, proceedingin situin the skin. As a result, the efficiency in the complex polyol as moisten the skin I largely reduced or even not defined.

In WO 01/70185 disclosed are antiperspirant compositions, structured by dibenzylideneacetone and containing dipropyleneglycol, for example, to facilitate the solubilization of the amendment. In the text the possibility of alternative use of polyethylene glycol with a molecular weight of from 200 to 8000 or methoxypolyethyleneglycol with a molecular weight of from 350 to 5000.

In USP 4280994 disclosed are antiperspirant compositions which contain polyethylene glycol with an average molecular weight of from 950 to 1600, for example, from 950 to 1050, or from 1300 to 1600, which are claimed as being more aesthetically and cosmetically attractive compared to a pencil, which contains a higher proportion of antiperspirant active substances, but does not include 6% nonionic surfactant. Aesthetic differences cannot be uniquely attributed to the weight of the polyethylene glycol. When such weight of the polyethylene glycol has been checked, the skin moisture decreased, the amount retained in the skin of moisture to the end of the test was lower than at its beginning.

In the application for U.S. patent No. 2004/0022750 not considered the problem of the formation of solid particles, the application does not refer to this issue, but it describes a method of reducing the particle size of the antiperspirant active substances to an average size of 2 m is m or less by grinding their suspensions in non-aqueous liquid medium, in which solid antiperspirant active substance is insoluble. The text illustrates the use of cyclomethicone (volatile silicones) as a non-aqueous liquid with the ratio of liquid to solid substance 3:1 by weight, but as a liquid medium are assumed to be many other classes of liquids, namely, cosmetic esters, glycols and polyols, non-volatile silicones, hydrocarbons, alcohols and mixtures of the above.

The PURPOSE of the PRESENT INVENTION

The aim of the present invention is to overcome or weakening of one problem or deficiency, and more than disclosed above.

The aim of certain embodiments of the present invention to provide an anhydrous antiperspirant compositions exhibiting positive bioavailability of the humidifier and the absence of a tangible solid particles.

The purpose of the various preferred embodiments of the present invention to provide compositions that contain particles astringent antiperspirant and counteract irritation.

SUMMARY of the INVENTION

The first aspect of the present invention relates to anhydrous antiperspirant or deodorant compositions containing

particles astringent antiperspirant salt;

oil-media

gelling the oil and

humidifier-poly is l,

in which the humidifier contains a low-molecular glycol

in the future this aspect is referred to as item 1.

The glycol which is liquid and not in a pre-formed complex with astringent antiperspirant salt, can be considered "free" polyethylene glycol.

The second aspect of the present invention refers to the process of weakening or prevent the formation of solid particles during the manufacture of the anhydrous antiperspirant or deodorant composition according to the first aspect, which includes stages:

education at elevated temperature liquid mixtures containing

particles astringent aluminium and/or zirconium, suspended in the oil carrier in which dispersed or dissolved gelling

and humidifier-polyol

followed by spontaneous cooling or by cooling the mixture to a temperature at which it solidifies the mixture, in which the humidifier contains a low molecular weight polyethylene glycol.

The resulting composition continues to contain "free" polyethylene glycol.

The third aspect of the present invention relates to a non-therapeutic method of suppression of sweating while reducing dryness of the skin by topical application of the composition according to the first aspect.

When using the low molecular weight polyethylene glycol (hereinafter sometimes abbreviated PEG) as a humidifier, which is not in complex with antiperspirant active substance, you can create an anhydrous composition containing a substantial amount of the humidifier-polyol, which is available immediately and can act as a humidifier in contact with the skin, without causing the formation of solid particles, or at least significantly reduces the proportion of the formed solid particles in comparison with the introduction of glycerol in the same proportion by mass.

"Anhydrous" in the context of the invention means that there is no separate aqueous liquid phase, and the content of free water is not more than 5%, preferably not more than 3%, particularly preferably not more than 1% and most preferably not more than 0.5 wt.% based on the weight of the entire composition. Associated with or located in the complex water, for example hydrated water in the antiperspirant salt is not considered to be free.

DETAILED description of the INVENTION AND the PREFERRED variants of ITS IMPLEMENTATION

The present invention relates to the selection of low-molecular-weight PEG, providing immediate availability of moisturizer when applied to the skin antiperspirant or deodorant compositions, such PEG is less inclined to cause the formation of solid particles during the manufacture of the composition at elevated temperatures used to dispersing or dissolving Geleos Atwater in oil-carrier. It is possible to achieve a positive skin hydration. It should be understood that the PEG include in a composition separate from the antiperspirant active substances, i.e. not in conjunction with them.

The composition according to the invention, considered in this application are in the form of solids or solids soft consistency (soft solids), the latter sometimes referred to as semi-solid substances or anhydrous creams. Solids are distinguished by the fact that retain their shape without side supports, despite the influence of Earth gravity. Solids according to the invention is typically used in the form of pencils. The hardness of such solids in General and pencils, in particular, can be measured using penetrometry, for example, using laboratory and industrial PNT the penetrometer with wax with the edge of the Seta (with a mass of 2.5 g and the weight of the holder and 47.5 g), the needle is accurately set the angle of the taper 9°10'±15", the needle is lowered to the surface of the sample with a flat upper surface and mark the depth of penetration after 5 seconds. It is desirable that the depth of penetration was less than 30 mm and preferably not more than 25 mm From the many appropriate solids, the penetration depth is at least 5 mm, for example, up to 20 mm Semi-solid substances, as their name suggests, not so rigid as solid. They can of extras is to derivati through the narrow opening under pressure, constituting approximately 3 pounds per square inch (about 20.7 kPa); requires holding the side wall, which prevents their slow spreading. The hardness of the semi-solid substances, as measured by the method of moving spheres, typically greater than 0.005 N/mm²usually below 0.5 N/mm²and in many compositions of their hardness ranges from 0.01 to 0.1 N/mm². Solids (solid pencils) distinguishes load during indentation of a sphere greater than 0.5 N/mm².

ASTRINGENT ANTIPERSPIRANT SALT

The mass ratio of astringent antiperspirant salt in the composition or mixture, if more than one salt, varies at the discretion of the manufacturer and is usually in the range from 0.1 to 60 wt.% of the composition. For use as a deodorant ratio is usually up to 5 wt.%, often at least 0.5% or at least 1% and in particular at least 2 or 3%. The effectiveness of the astringent salt suppression of sweating increases with the increase of its weight, so usually choose the ratio is in the range from 5 to 30 wt.% and in many desired compositions from 10-15 wt.% up to 26 to 30 wt.%.

Astringent antiperspirant salts for use in the present invention often binders are selected from salts of aluminium, zirconium and mixed salts of aluminum/zirconium, not necessarily located in the complex. Pre is respectful of an aluminum salt, Zirconia and aluminum/zirconium include the halides, in particular chloride, and particularly preferred salts are basic salts, in other words those in which part of the halogen within empirical formula associated substituted with hydroxyl groups. Highly desirable salt-chlorhydrate.

Halogenate aluminum are usually described General formula Al₂(OH)_xQ_y·wH₂O, in which Q represents chlorine, bromine or iodine, x is variable from 2 to 5 and x+y=6, while wH₂O represents a variable number of water molecules. Hydrochloride aluminum contains a mixture of several different types of polymers in different ratios depending on the molar ratio of aluminum and chlorine and conditions used during synthesis. All such mixtures can be used according to the present invention. Especially, it is desirable to use a connection which is usually referred to as activated hydrochloride aluminum or hydrochloride aluminum with increased activity, sometimes abbreviated as AACH, in which the proportion of the more active species, such as varieties of Band III (certain conventional chromatographic method), higher because of the features of the method of synthesis. One definition of an active substance, in this EP 6739, it contains more than 20% Band III. Other ways of sin is ESA AACH described in EP 191628 and EP 451395. AACH often receive a selection of the hydrochloride of aluminum from dilute solution under strictly controlled conditions of reaction/maturation/dehydration/drying. AACH can be found on sale by its name or by activated or increased activity; he comes from such suppliers as Reheis, Summit Research and Β Κ Giulini.

The active substance of zirconium is usually possible to describe the General empirical formula: ZrO(OH)_2n-nzB_z·wH₂O, where z is a variable from 0.9 to 2.0 so that the value 2n-nz is zero or a positive number, n is the valency of B, and Β is selected from the group consisting of chloride, other Halogens, sulpham, sulfate and mixtures thereof. Possible hydration in a variable degree presents wH₂O. Preferably Β represents chloride, and the variable z is in the range from 1.5 up to 1.87. In practice, such zirconium salt is usually not used in its pure form and as a component of the United antiperspirant on the basis of aluminum and zirconium.

The above-mentioned salts of aluminum and zirconium, may contain coordinated and/or bound water in various quantities and/or may be present in the form of polymeric species, mixtures or complexes. In particular, basic salts of zirconium often represent a range of salts containing different number of hydroxyl groups. About obinna preferred may be the hydrochloride of aluminum/zirconium.

Can be used antiperspirant complexes on the basis of the above astringent aluminium and/or zirconium. The complex is often used in connection with a carboxyl group, it is advantageous that this was the amino acid. Examples of suitable amino acids include dl-tryptophan, dl-β-phenylalanine, dl-valine, dl-methionine and β-alanine, and preferably glycine which has the formula CH₂(NH₂)COOH.

In some embodiments, implementation of the present invention, it is desirable to use a combination of halogenated aluminum (especially clorhidrato) and clorhidrato zirconium together with amino acids such as glycine, which is disclosed in US-A-3792068 (Luedders et al). Some of these complexes Al/Zr in the literature often referred to as ZAG. The active substance ZAG usually contain aluminum, zirconium and chloride ratio Al/Zr in the range from 2 to 10, in particular 2 to 6, the ratio of Al/Cl from 2.1 to 0.9 and a variable number of glycine. The active substance of this preferred type are supplied Westwood, Summit and Reheis.

Particularly preferably, antiperspirant salts were at least essentially free of aluminum sulphate, which means that its mass fraction of the total mass of all present antiperspirant salt is less than 5%, in particular less than 3% and in particular less than 1%. Very suitable it is full of the e absence.

Other active substances which may be used include binders titanium salt, such as described in GB 2299506A.

The particle size of the source material for binding of antiperspirant salts is often in the range of 0.1-100 μm and, in particular, is at least 0.2 μm. In many desired products at least 95 wt.% the source material has a size less than 50 microns, often with an average particle size of from 3 to 30 μm and in many cases from 5 to 25 microns, and in some very desirable types of source material - from 10 to 25 μm. Profitable that by selecting the primary humidifier-polyol according to the present invention and particularly preferred variants of its implementation can limit the particle size of the antiperspirant salt in the compositions according to the invention after fabrication at least essentially to less than 100 μm, for example so that at least 95%, preferably at least 99% and, in particular, 100% of the particles had a diameter below 100 microns.

Where it is desirable to obtain antiperspirant products that after topical application to the skin form no more than light deposits, it is preferable to select the source materials, which contain mainly nepalee solid particles, for example not more than 5% or, in particular, not more than 2%, especially less than 1% of hollow spherical particles with a diameter wise μm. Hollow particles can be eliminated using a suitable apparatus and grinding.

The mass of the particles of the active antiperspirant salt in this document usually includes any present hydration water.

Oil-carriers

The compositions of the present invention contain at least one oil carrier, by which is meant a compound which is not miscible with water (alternatively be described as hydrophobic or lipophilic) and which is liquid at a temperature from 20°C to a temperature of at least such that the gel is dissolved or dispersed in the oil-carrier oil, which is composed of particles of ingredients, such as antiperspirant salt suspended. It should be understood that this temperature of dissolution depends on the gelling or mixture of geleobrazovanie, and from oil or mixture of oils. Usually the boiling point of the oil exceeds 150°C and is often equal to at least 200°C. In this paper, the term "oil carrier" does not include liquid PEG-humidifier.

Mass fraction of oil-carriers in the compositions according to the invention is usually selected in the range from 20 to 90% and in many cases is at least 30%.

Oil-carriers typically comprise at least 40 wt.% anhydrous suspension of the composition, and in many cases at least 45%. Max is I's share of oil-carriers in pencil or solid soft consistency is usually not more than 90 wt.%, in many desired compositions up to 80% and in some particularly preferred compositions - 70% wt./wt. the final composition. The composition containing 45 to 60% or 65% oil-nositeli, make it easy to include in the composition an effective amount of antiperspirant salt, for example 15-26% or 30%, humidifier and a sufficient amount of gel to achieve the desired hardness. The share of oil-carriers in the composition is additional to the share of the humidifier.

Oils that can be used according to the present invention, generally belong to 2 categories, namely, silicone oils (sometimes called organosilicone oils because organosiloxane) and resiliancy oils. In addition, each of the categories can be divided into two types, namely, volatile and non-volatile. The choice of balance between silicon and asilicone oils and between volatile and non-volatile oils remains at the discretion of the manufacturer of the cosmetic composition, which will take into account, among other things, sensory and other physical properties, which he wished to give the final product, as well as any limitations resulting from the choice of gelling (amendment) or additional ingredients.

Under volatile in the framework of the invention means the oil has a measurable vapor pressure PR is 25°C. Typically the vapor pressure of the volatile oil at 25°C is in the range of at least 1 PA, or preferably at least 10 PA, although, as a rule, it will be less than 4 kPa (30 mm Hg). Non-volatile can be considered as oil, which at 25°C creates a vapor pressure of less than 1 PA. Choosing silicone and/or asilicone oil in different ratios and volatile and non-volatile oil in different ratios, it is possible to obtain compositions having different sensory properties.

It is desirable to include volatile silicones, for making the applied film is more dry to the touch after the composition is applied on the skin.

Volatile polyorganosiloxane can be linear or cyclic, or a mixture thereof. Preferred cyclic siloxanes include polydimethylsiloxane, especially those which contain from 3 to 9 silicon atoms and preferably not more than 7 silicon atoms, and most preferably from 4 to 6 silicon atoms, which is often referred to as cyclomethicone. Preferred linear siloxanes include polydimethylsiloxane containing from 3 to 9 silicon atoms. Volatile siloxanes typically have a viscosity below 10^-5m²/s (10 cSt) and, in particular above 10^-7m²(0,1 cSt), linear siloxanes typically have a viscosity below 5×10^-6m²(5 cSt). Volatile silicones can also on the part of the branched linear or cyclic siloxanes, such as the aforementioned linear or cyclic siloxanes substituted with one or more additional group-O-Si(CH₃)₃. Examples of commercially available volatile silicone oils include oils having the designation varieties 344, 345, 244, 245 and 246 from Dow Corning Corporation; Silicone 7207^TMand Silicone 7158^TMfrom Union Carbide Corporation; and SF1202^TMfrom General Electric.

Often mass fraction of volatile silicone oil is at least 10 or 20% by mass of silicone oil in the composition of the present invention and many particularly suitable compositions is at least 70% and especially at least 85 wt.% silicone oils. In other vysokoperedelnyh compositions of the present invention, for example, if you want to get translucent composition or compositions, leaving poorly visible remnants of the mass fraction of volatile silicone oils is usually less than 50%, preferably less than 30%, such as 0 or 5% to 15 or 20% silicone oil.

Oil-carriers used in the compositions according to the invention may alternatively or additionally contain one or more non-volatile silicone oil, which includes polyalkylene siloxanes, polyalkylacrylate and copolymers of polyethylsiloxane. They can accordingly choose from with-polyols dimetikona and dimeticone. Commercially available, Neleus the e silicone oils include products, available under the trademarks of the series Dow Corning 556 and Dow Corning 200. Other non-volatile silicone oils include oils trademark DC704. The inclusion of at least a small amount of non-volatile silicone oil with a high refractive index, such as more than 1.5, in quantity, for example at least 10 wt.% silicone oils (preferably at least 25-100% and in particular 40 to 80%)may be useful in some compositions, for example those in which it is desirable to reduce visible fat and/or get a translucent composition, in which the refractive index dispersed particles of antiperspirant salt corresponds to the ratio of the oil carrier (taking into account the impact of any moisturizer that forms a single phase with a carrier oil). Many asilicone oils act as softeners. Any asilicone oil provides a balance silicone oils.

Liquid silicone oil can comprise up to 100 wt.% water-immiscible liquid oil carrier, for example in many desirable embodiments, the implementation of their mass fraction is selected in the range from at least 20 or 30% oil-carriers, often in the range of at least 50% and in some particularly preferred embodiments, the implementation of the mass fraction is at least 70 wt.%. In the above-mentioned various leagues in other desired embodiments, the implementation of the present invention asilicone oil make up most of the mass percentage or even 100% of the oil phase, for example, at least 20 or 30%, in particular is selected in the range from at least 50% and particularly selected in the range of at least 70%.

Asilicone oil

Developer formulations of the compositions of the present invention may include one asilicone oil and more, which are sometimes called alternative asilicone hydrophobic or water-immiscible liquids, in addition to or in lieu of all or one faction silicone oils mentioned above. Such oil, as described above, are liquids at 20°C and standard pressure, in fact, are preferably liquid at 15°C, and beneficial oils having a boiling point of at least 150°C. Data on the melting points and boiling points for chemical compounds can easily be obtained from reference books, such as the CRC Handbook of Chemistry and Physics, published by CRC Press, often together with an indication, whether soluble compound in water or can be mixed with it. For any connection for which such data is not available from the literature, they can easily get any chemist, using conventional methods. Various asilicone oils are volatile and many are non-volatile.

If you are using non-volatile oils, they are often chosen from one or more of the following classes of organic compounds, namely, hydrocarbon oils, ester mA who ate and essential oils.

And volatile and non-volatile hydrocarbon oils readily available. Volatile oils include, in particular, paraffins and ISO, the content of the intermediate number of carbon atoms, for example selected in the range from 8 to 25 carbon atoms, and often at least 10 carbon atoms depending on its molecular structure. However, non-ideal mixture of hydrocarbons tend to have a higher volatility than can be assumed from separate components, and the melting point and boiling points tend to increase with increasing molecular weight, thus, these numerical limits are only guidelines, in fact there is a diffuse transition to the hydrocarbons, which are clearly non-volatile. Volatile hydrocarbons can be used instead of all or fractions of volatile silicone oils that are defined in this document previously. In many desired the compositions according to the invention, a volatile hydrocarbon is from 0 to 20 wt.% and especially from 0 to 10 wt.% mix oils in General.

Non-volatile aliphatic hydrocarbons are generally chosen from mineral oils, hydrogenated polydecene and hydrogenated polyisobutene. Non-volatile hydrocarbons can be included because of their desirable properties, since many of them have softening properties, have the same or lower Vascos the ü, and the average refractive index, for example about 1,46 or 1,47, they usually help to reduce the visibility of astringent antiperspirant salts, locally adhered to the skin or clothing. Non-volatile hydrocarbon oil is preferably present in the amount of 0-50% wt./wt., in some preferred embodiments, from 0 to 10% wt./wt. oils and other advantageous variants of implementation - 10% wt./wt. oils. Suitable non-volatile hydrocarbons include hydrogenated polydecene and vaseline, the latter is usually a wax-like substance having a low melting point, for example, in the region of 35-45°C.

Ester oils are particularly useful class asilicone oils. Other suitable hydrophobic carriers include liquid aliphatic or aromatic esters. Typically these oils are non-volatile. Ester oil can be aliphatic, aromatic or contain both aliphatic and aromatic group. Many of the desired aliphatic esters contain at least one long-chain hydrocarbon group, for example containing from 8 to 25 carbon atoms, derived from a monohydroxy alcohol or monocarboxylic acid. Suitable aliphatic esters can be derived from monohydroxy alcohols, such as selected from C₁-C₂₀alifatic the ski alcohols, esterified carboxylic acid selected from C₈-C₂₀manualconfig acids and C₈-C₂₀arcangioli acids. Such esters include isopropylmyristate, laurierated, isopropyl, Diisopropylamine and diisopropylamide. Other suitable ester oils include glyceride oil and, in particular, triglyceride oils derived from glycerol and fatty acids, sometimes alafinova unsaturated instead of saturated, containing at least 6 carbon atoms and, in particular, a natural oil derived from unsaturated carboxylic acids containing from 16 to 20 and, in particular, to 18 carbon atoms.

Suitable liquid aromatic esters or mixed aromatic/aliphatic esters are preferably derived from benzoic acid. Examples of such esters include the appropriate C₆-C₁₈alkylbenzoates or mixtures thereof, including, in particular, C₁₂-C₁₅alkylbenzoates. Many suitable esters of benzoic acid are available under the trademark Finsolv. Other aromatic esters, the use of which can be seen in this document, contain two aromatic residue. The benzyl benzoate, although suitable, preferably essentially absent, constituting, for example, not more than 5% and in particular not more than 3% or 1 wt.% oil mixture is specifically excluded. Preferred dual aromatic esters contain linear or branched alkyl chain, for example a length of from 1 to 3 carbon atoms, built between ester groups or substituted phenyl groups simple ether.

Aliphatic esters typically have an intermediate refractive index, and therefore they are typically used because of softening agents. Aromatic esters usually have a higher refractive index, for example approximately 1,49-1.50 and even higher refractive index, if there are two aromatic substituent, which makes them particularly suitable for the preparation of translucent compositions containing particles of astringent antiperspirant salt and even salt containing zirconium.

Ester oils, aliphatic or aromatic preferably contain from 0 to 60%, preferably at least 10 or 15% to 35 or 40% wt./wt. oils, for example, in various embodiments, the implementation of highly preferably 15-35%. It should be understood that the ester oils mentioned in this document are generally considered non-volatile and therefore they can be used as a substitute for non-volatile silicone oils, for example silicone oils with similar refractive index, full or partial, at the discretion of the developer formulations.

Natural oils containing one triglyceride and more, include the seed oil of coriander for the derivatives petroselinic acid, oil of seeds of impatiens balsimina, fat seed parinarium laurinarium or oil seeds sabastiana brasilinensis for derivatives CIS-prinarovie acid, digidratirovannogo seed oil castor derivatives conjugated linoleic acid, seed oil borage and evening primrose oil for derivatives of linoleic and linolenic acids, oil aquilegia vulgaris for columbinus acid and sunflower, olive and safflower oil for derivatives of oleic acid, often together with linoleic acid. Other suitable oils can be obtained from hemp, which can be processed to derive stearidonic acid, and corn oil. Especially suitable natural oil due to its characteristics and availability includes sunflower oil, the composition of which varies from rich in glycerides of oleic acid to rich in glycerides of linoleic acid; "rich" means that the content of this acid is higher than acid other name.

The share of natural oil in the composition is often selected in the range from 0.1 to 10 wt.% mix media, especially in the range of at least 0.25 wt.% and in particular at least 0.5 percent. Often its mass fraction is selected within up to 6 wt.% and there are many ways to implement 4% oil carrier. In particular, a convenient range is from 0.75 to 3% wt./wt. oils-media.

Essential oils are another case of suitable oils. Preferably, the essential oil, which may be considered in this invention include liquid simple aliphatic esters, which can be obtained from polyglycol, in particular, from polypropylenglycol, BCPs, the latter preferably contains at least 3 mers, for example, 3-20, monohydroxy alcohol. Monohydroxy alcohol often contains 3-20 carbon atoms. Since the molecular weight of BCP increases, therefore, the length of the chain monohydroxy alcohol may decrease. Thus, for example, suitable essential oils can vary from low molecular weight BCPs with long-chain fatty alcohol, such as ministerului ether BCP-3, to the lower alkyl esters with BCPs higher molecular weight, for example, ether, named in the CTFA Handbook butyl ether BCP-14. The share of such esters is preferably from 0 to 30 wt.% and preferably at least 5 wt.% oils, for example, preferably up to 20 or 15%.

In many desirable embodiments, the implementation of the present invention, the composition contains at least one ester oil and at least one simple ether, for example, the mass ratio of the total number of air: a simple ester is from 5:1 to 1:. In these or other embodiments, the implementation of the composition preferably also contains natural oil, and essential oil, for example selected in the range of mass ratios from 1:5 to 1:20 and in particular from 1:9 to 1:15.

Another class of oils carriers, which can be considered part of the invention and which are particularly wish in the variants of implementation, which is used amide gel are water-immiscible aliphatic alcohols, boiling point exceeding 100°C, including, in particular, aliphatic alcohols with branched chain containing from 12 to 25 carbon atoms, such as isostearoyl alcohol and octillery. In such scenarios, the implementation of such alcohol oils range from 10 to 50 wt.% oil.

Humidifier

In the present invention, the humidifier essentially contains a choice of low molecular weight polyethylene glycol (PEG) for incorporation in anhydrous partial suspensions of antiperspirant salt. This substance is a liquid at ambient temperature or melt at the temperature of treatment, usually used for the manufacture of gelled wax pencils, or at a lower temperature.

The selection is based on establishing the inventors of the fact that such humidifiers simultaneously meet two criteria. First, they can be. which of the extent which exceeds, for example, the rate of propylene glycol, and similarly for glycols containing 4-6 carbon atoms, and secondly, they allow to avoid the risk or at least reduce the risk of formation of solid particles, which can occur if the glycerol is an excellent moisturizer, or propylene glycol, less good moisturizer. Can be used one oligomer or mixture of oligomers of polyethylene glycol. They have a good and preferably superior bioavailability and profitable show availability during the normal period during which the composition remains on the skin, and, as a rule, have immediate bioavailability.

PEG in the compositions of the present invention has a low molecular weight, average molecular weight of not more than 820, preferably not more than 620, in particular up to 520 and in particular to 420. The polymer PEG preferably has an average molecular weight of not less than 150 and in many desirable embodiments, the implementation of the average molecular weight of the mixture of PEG is at least 190. The PEG polymers with lower molecular weight tend to be progressively more efficient from the standpoint of prevention of agglomeration of the active antiperspirant substance, at least until molecular weight of about 500 or below and, on the contrary, it effectively is Yunosti (as a moisturizer) has a tendency to decrease in wt./wt. respect, as its molecular weight increases more than 500. This is especially noticeable when molecular weight of about 1000 or higher.

Assume that a commercially available low molecular weight PEG polymers often contain a mixture of oligomers. Especially, it is desirable to use the polymer (mixture), which is free, or at least essentially free from dimer. Essentially free from dimer profitable means less than 5 wt.% mixture, more preferably less than 3% and in particular less than 1%.

It is desirable that the total mass fraction of PEG oligomers of the formula H-(OCH₂-CH₂)_n-OH, in which n≥14 units was less than 10% by weight of PEG and preferably less than 4%. It is beneficial to have at least 95 wt.% oligomers of PEG had n=3-10.

Advantageously, by selecting a low molecular weight PEG and, in particular, the preferred PEG manufacturer can obtain anhydrous suspension antiperspirant pencil or soft product-pencil, giving noticeable hydration without solid particles or, in the worst case, a reduced solids content, the manufacturer is not required to include at least the predetermined relation of the carrier of odorants to the humidifier. In addition, more affordable humidifier to provide moisture to the skin, if it is simply mixed with the composition, unlike the case when the pre-forms a complex with antiperspirant active substance.

Although it may be convenient to include in the composition a small amount of polymer is PEG, such as 0.1%, it is preferable to use a higher number, more preferably at least 0.5%, and to increase the moisturizing effect. It is preferable to include at least 1% and many attractive compositions contain at least 1.5 wt.% polymer PEG. Attractive is its content of not more than 10% and in many desirable embodiments, the implementation of up to 7.5% and in particular up to 5 wt.% of the composition. Preferably inversely proportional to reduce the content of the polymer PEG, entered into the composition, by increasing its molecular weight above 450-500. For example, it is preferable that its content does not exceed 1.5-2% with a molecular weight of 820, but up to 5% when the molecular weight of 600.

One aspect of the present invention relates to anhydrous compositions containing particles of astringent antiperspirant salts and low molecular weight polyethylene glycol, which is a 2-day hydration test described in this application provides an increase hydration in relation to the corresponding test location before processing. The corresponding aspect includes the manufacture of such compositions using the process described in this application and the local application to the skin according to the application to the skin, opisannogo this application.

In such compositions, it is preferable to use polyethylene glycol, which is in the specified 2-day test hydration provides an increase hydration of at least 1.0 and preferably at least a 2.5 in relation to the corresponding test location before processing.

The proportion of PEG, if desired, can be selected on the proportion of antiperspirant active substance and in practice, the PEG is present in significantly or very significantly lower ratio in relation astringent antiperspirant active substance. The preferred mass ratio of antiperspirant active substances to the polymer PEG is a choice of accommodation ranging from 4:1 to 40:1, and often from 8:1 to 20:1 and, in particular, within these ranges, if the average weight of the polymer ranges from 150 or 190 to 420 or 450. Such mass ratio of antiperspirant salt (AA) to the polymer PEG are particularly suitable for antiperspirant composition, for example, containing at least 15% wt./wt. and, in particular, at least 20% wt./wt. antiperspirant salt. If you are using a lower ratio of antiperspirant salt, the preferred minimum ratio of AA:PEG increases from 1.5:1 with 2% AA 2:1 with 5% AA up to 3:1 with 10% AA and other content of AA to 15% is determined by interpolation.

Benefit from the Pach the project with the composition of PEG compared with glycerol may be obtained through any of the two aspects or both of them. On the one hand, the amount of PEG that can be included, like the amount of glycerin that it would be desirable to use, with the advantage that agglomeration of antiperspirant active substances does not occur, or at least it is significantly reduced without the need to use media odorants. On the other hand, the relative amount of PEG can be increased without reaching the point at which the formation of inappropriate solids.

Particularly desirable compositions of the present invention have an index of solid particles not more than 1,25 under test on solid particles with a rating on a four point scale.

The use of low molecular weight PEG here, showing good moisturizing bioavailability, gives the greatest advantage when used in conjunction with the antiperspirant active substances, and containing aluminum, and zirconium, such as active substances have a tendency to reduce the humidity or prevent the moisture to a greater extent than the active substance on the basis of only aluminum.

Preferably essentially to avoid the inclusion of alternative is not located in the complex and unbound polyhydric alcohol in the composition, in order to avoid at least partial elimination of the advantages obtained through the use of selected polymer PEG. the Tim is denoted polyhydric alcohol, which is not in complex with antiperspirant salt or not associated with the media odorants. The total contents of any such unrelated and not in the set of alternative polyhydric alcohols should not exceed 1 wt.%, preferably not greater than 0.5% and ideally should be absent.

The oil carrier is usually present in mass with respect to the PEG-humidifier than 6:1 and in many particularly suitable options exercise of more than 8:1. The ratio is usually less than 150:1, advantageously less than 60:1 and preferably less than 30:1. The presence of oil-carriers in the high mass with respect to PEG reduces sensory deficiencies, which would be obvious if there is present a higher amount of PEG, it would have occurred if the PEG was used as a solvent, in which the antiperspirant active substance was subjected to the grinding.

A significant advantage of hydration obtained due to the introduction of free low molecular weight PEG and, in particular, PEG with an average molecular weight of less than 620. It is noted that such compositions are turning to another issue, which is the result of applying certain antiperspirant compositions. The compositions according to the invention can avoid or reduce skin irritation or even to help reduce irritation underarms, for example, calling the spent shaving. This combination of benefits is especially significant.

Another aspect of preferred embodiments of the present invention relates to anhydrous compositions, the content of particles astringent antiperspirant salts and low molecular weight PEG-humidifier, which reduce the rate of irritation in the 29-day irritation test described in the application, between day 0 and day 29.

Especially, it is desirable to use such compositions, optionally or preferably together with triglyceride oil, the relative amount of PEG and antiperspirant salts, which reduce the rate of irritation specified in 29-day test of irritation between day 0 and day 29 of at least 0.5 units, and especially at least 0.75 units.

Gelling

Oil-carriers in the compositions according to the invention is thickened by introducing a sufficient number of selected organic gelling (amendment), in order to achieve the desired hardness of the resulting product at ambient temperature. Usually gilotinirovaniya occurs due to the formation at elevated temperatures movable liquid oil phase, which is distributed gelling, and, in particular, due to the dissolution, so that when the composition is cooled or allow it to cool below the freezing temperature, p is our selves solid or semi-solid product.

The content of gelling that it is preferable to use depends on a number of factors, including, in particular, the inherent gelling ability to create a gel, the choice of oils carrier, the desired hardness and, finally, treatment conditions, such as shearing force, which is added during mixing in the freezing temperature. Accordingly, for solid pencils mass of gel is often chosen in the range from 1 to 60 parts per 100 parts of oil carriers and preferably from 2 to 50 parts. For semi-solid pencils mass of gel is often chosen in the range from 1 to 40 parts to 100 parts, preferably from 2 to 30 parts.

Suitable classes of geleobrazovanie include waxes, including related waxes substances forming fiber polimernye the builders, soluble in oil organic polymers, optional copolymerizable with polysilicon and silicone elastomers.

One class of builders, which is desirable because of its long-proven ability to create solid, or soft, or semi-solid substances, contains waxes. In the framework of the invention, the term "wax" includes not only substances of natural origin, which are solid, similar to the touch on the wax and insoluble in water, but melt or at IU the e form a single phase oil-carriers at a slightly higher temperature, typically between 50 and 95°C, often at least 60°C, such as beeswax, candelilla spermeceti or Carnauba wax, and other organic substances having similar properties. Such other waxes include hydrocarbon waxes, for example paraffin wax, mineral wax and microcrystalline wax which hydrocarbon waxes can be synthetic, such as polyethylene with a molecular mass of 400-10000 daltons; and derivatives of waxes or wax components are natural waxes such as ester components found in bee wax, selected whether they are from natural wax, synthesized or are modified beeswax, including such geleobrazovanie as fatty alkyl esters (≥₁₆), for example esters stearate, esters of stearate/behenate, stearyl-beeswax or silicones-beeswax, such as geleobrazovanie, available from Koster Keunen, for example, K62, K80, K67 or K82.

Other suitable waxes include solid ester derivatives glyceryl or glycol, typically with linear saturated fatty acids, usually containing a substantial fraction of the residues of the C_16-22acids that can be synthetic or obtained by hydrogenation of the corresponding natural oils, for example glyceridic oils described above, including gidrirovannoe castes the world oil. Other waxes include petroleum waxes, silicone wax polymers, the content of alkyl substituents with a length of at least C₁₀; and, importantly, waxy fatty alcohols, which are usually linear and often contain from 14 to 24 carbon atoms, such as stearyl alcohol, cetyl alcohol or beganovic alcohol or a mixture of two of them or more, especially if they are obtained, possibly indirect, from natural raw materials.

Within the class of wax geleobrazovanie often desirable to use a mixture of geleobrazovanie with different point melting/softening, for example, at least one melting at temperatures up to 70°C, such as stearyl alcohol, and the other, melting at a temperature above 70°C, preferably above 75°C and, in particular, in the range from 75 to 90°C, such as gidrirovannoe castor oil, widely available variety which has a melting point of about 80°C. Such a combination is particularly suitable for solid pencils. Other waxes with high melting point, which may be considered include other hydrogenated triglycerides aliphatic or fatty esters or hydrocarbon waxes having a melting point in the desired range, or a mixture of two such waxes and more. You can easily find them in the literature. The mass ratio of waxes with a low and high point plavini the compositions according to the invention is often in the range from 2.5:1 to 7.5:1 and, in particular, from 3:1 to 6:1.

When used as the primary or sole gelling fraction of the total mass of the wax in the composition according to the invention is often selected in the range from 6 to 25% and in overlapping set of compositions, in other words, it is preferable that such wax gelling ranged from about 10 to about 50 parts by weight per 100 parts of oil-carriers. The hardness of the resulting products is increasing with increasing mass fraction of the gel, especially if not used mixing with the inappropriate efforts shift within 5°C above the pour point of the composition alone.

The second class of geleobrazovanie suitable for use in the present invention, includes polimernye geleobrazovanie forming fibers. Such geleobrazovanie usually are chiral and are characterized by their ability to crystallize in the form of long thin filaments or fibers. Many of these geleobrazovanie forming fibers which have been identified to date include the following subclasses from a to d:

a) hydroxystearate acid and its ester or amide derivative, including, in particular, 12-hydroxystanozolol acid, the main gelling in USP 5650144, USP 5591424 and USP 5429816;

b) forming a fiber geleobrazovanie, with whom containing a series of amide bond, including, in particular, amides, N-acyl amino acids and esters, described in US-A-3969087, such as, in particular N-lauroyl-L-glutamic acid di-n-butamid and/or additional choice in USA-2002/0159961 in which alcalina group R³in the N-acyl Deputy-CO-R³in the formula differs in that it contains from 7 to 10 carbon atoms and may be branched, of which one preferred gelling is 2-ethylbutanol-L-glutamic acid di-n-butylamide; amide derivatives, which are mentioned in WO 98/27954, especially alkyl N,N'-dialkylacrylamide; cyclic ester derivative of aspartame, especially cyclopeptide that are mentioned, for example, in WO 2003/059307; aminopropane cyclohexane mentioned in US-A-6410003;

c) other forming fiber geleobrazovanie include lanosterol, as described in US-A-6251377, and the combination of Sterol and complex Sterol ester, as described in WO 00/61096, for example, gamma-oryzanol and β-sitosterol;

d) other forming fiber derivatives include esters of fatty acids and aldos, including such derivatives of maltose, which is described in US6589515, and, in particular, esters of fatty acids and cellobiose, which are described, for example, in US6248312 and US6458344, such as a product containing predominantly cellobiose octanone and a smaller fraction of cellobiose heptanesulfonate. Chem ones forming fiber esters of fatty acids cellobiose described in WO2002/32914; in them, the Deputy carboxyl group at the anomeric carbon atom differs from the Deputy fatty acids to other sites around the rings cellobiose, for example, is an aromatic or cycloaliphatic, and not linear alkanoates. Description in this document of geleobrazovanie forming fiber that includes a description of such geleobrazovanie, data in the respective descriptions of invention to the patent identified by the above numbers.

Can be used mixtures of substances within each subclass of gelling/amendment from a to d. The number of gel-forming fiber, it is desirable to use, often selected in the range of 2 to 30 parts per 100 parts of oil and specifically for amide of geleobrazovanie subclass b is useful when the mass fraction can be so low that ranges from 2 to 10 parts per 100 parts of oil and, in particular, if you are using amide N-acylaminoalkyl and/or cyclopeptide.

Another class of builders for water-immiscible liquids which can be used according to the present invention, according to their disclosure in the patent literature relating to the preparation of antiperspirant compositions in the form of solid substances in soft or solid consistency of the pencil, polymer includes heliopaths the Lee. Examples soluble in oil polyamides or copolymers of amide/silicone described in US6451295 and WO 9736573. Mass fraction of such polymer soluble in oil of geleobrazovanie often is in the range from 2 to 12 parts per 100 parts of oil.

Forming a fiber geleobrazovanie and, in particular, geleobrazovanie obtained from aldos can be used together with geleobrazovanie-polymers. Suitable geleobrazovanie-polymers include polysaccharides, esterified fatty acid, one of the most superb examples of which include dextrin palmitate: polyamides, which are discussed in US 5500209, such as the product available under the trademark Versamid^TMwhich can be obtained from a diamine and adipic acid; block copolymers of alkylene/Allen, for example, block copolymers of styrene and ethylene, propylene and/or butylene, for example, known as block-copolymers, SEBS, many of which are available under the trademark Kraton^TM. Themselves block copolymers are often supplied in a compatible oil medium such as a hydrocarbon oil. Mass fraction of such polymers (based on the weight of the polymer and not the total weight of polymer plus its carrier) is often selected in the range from 1 to 20 parts per 100 parts of oil-carriers, the number is selected depending on the desired degree of thickening or structureof is occurring and the effectiveness of the chosen polymer in the liquid mixture.

Another class of geleobrazovanie that can be used according to the present invention includes a silicone elastomer, which contains threads, features a sewn in the desired degree alkionovymi groups. Elastomers have the ability to absorb greater, often much greater than their own weight, the number of compatible oils, usually silicone oils, hydrocarbon oils and ester oils. Suitable silicone elastomers silicone described, for example, in US5942215. Mass fraction of silicone elastomers that can be used, it is desirable can be the quantity that is needed to achieve the desired hardness of the product; this number is often selected in the range from 6 to 30 parts (based on active ingredient) per 100 parts of oil-holders or, if the elastomer is used in conjunction with additional gelling, less than 6 parts of elastomer per 100 parts of oil-carrier can be used, for example, 0.1 to 3 parts per 100 parts, in order to benefit from the desired sensory properties of the elastomer. The elastomer is typically available in the form of thickened oil carrier, such as a volatile silicone oil, for example, as described above, typically at a concentration in the oil is from 15 to 50 wt.%.

In some very desirable options for implementing the present invention antiperspirant whom is osili contain in addition to the oil-carrier and particulate antiperspirant active salt:

i) PEG with an average molecular weight of from 190 to 500 in an amount of 0.1-10% wt./wt.,

ii) 0.1 to 6% wt./wt. triglyceride oils are unsaturated aliphatic monocarboxylic_16-18acid and

iii) 0.1 to 6% wt./wt. triglyceride wax, hydrogenated unsaturated aliphatic monocarboxylic_16-18the acid.

Optional ingredients

Optional ingredients include washing agents commonly present in an amount up to 5 or 10% wt./wt., to help remove the composition from the skin or clothing. Such washing agents typically represent nonionic surfactants such as esters or ethers containing as C_8-22the alkyl residue, and hydrophilinae residue, which may contain polyalkylene group (POE or POP) and/or polyol, such as glycerol or sorbitol.

The compositions herein can include one cosmetic additive and more traditionally considered for cosmetic solids or solids with a smooth consistency. Such cosmetic additives may include means improving skin sensations, such as talc or finely dispersed polyethylene with a high melting point, for example in an amount up to about 10%, and often in total amount of from 0.5 to 6%; inorganic particulates, preferably condisder the data, such as fumed silicon dioxide, for example, in an amount up to 2%; a means of improving the skin, such as allantoin, vitamins or lipids, for example, in an amount up to 5%; colorants; preservatives, such as equivalent, often in quantities of from 0.01 to 0.1%; chelates metals, such as EDTA, for example, in an amount up to 1%; a means of cooling the skin, such as menthol, menthol and derivatives, often in an amount up to 2%; in all cases the percentage is given in relation to the weight of the composition. Commonly used additive is perfume (fragrance), which is usually present in concentrations of from 0 to 4% and in many formulations from 0.25 to 2 wt.% song.

The way to obtain

The compositions of the present invention can be obtained by methods that were used up to the present time, using the same ingredients that were used in the absence of PEG-humidifier to receive solid or semi-solid pencils, respectively.

In General, suitable General method of manufacturing a solid or semi-solid pencil involves the following stages:

a) formation of a mixture of oil phase with an organic gelling, dispersed therein;

b) heating the mixture to elevated temperature at which the gel is melted or dissolved in an oil phase;

c) the introduction of PEG-humidifier in maslany the phase;

d) introducing particulate astringent antiperspirant salt in an oil phase; stage c) and (d) respectively are performed before, after or simultaneously with the stages of a) or b);

e) introducing the resulting mixture containing the humidifier and antiperspirant salt in the feeder or solid pencils, an alternative in the form and

f) cooling or spontaneous cooling the resulting mixture below the freezing temperature; at least part of this stage is optional in front of stage e).

The temperature to which dispersible mixture is heated at the stage b), depends on the point of melting or dissolving the selected gelling or, if you use a combination of geleobrazovanie, the one that has the highest melting or dissolution. This temperature is usually equal to at least 60°C and in many cases is in the range from 70 to 140°C. Preferably geleobrazovanie and oils choose together so that the mixture at the stage b) is not to be heated above 100°C, and in many desirable embodiments of implementation, it is heated to a temperature of from 75 to 90°C.

In the manufacture of semi-hard pencil may be advantageous to expose cooling the mixture to intensive mixing at a time when its temperature corresponds to the temperature of solidification alone, so in order to get the consistency of cream, not a hard pencil.

With regard to the aforementioned method of manufacturing an organic substance indicates the presence of carbon in the gel, which is solid at 40°C and melts or dissolves in the oil phase at a temperature up to 150°C.

The order of introduction of the other ingredients in the oil is at the discretion of the manufacturer. In some desired embodiments, the implementation of a mixture containing oil, gel and moisturizer, reassembled before stage b), and astringent salt is introduced after stage b) and, in particular, after the mixture cooled, including spontaneously, for example, below 70°C. the Introduction of salt after stage b) is advantageous in that it reduces the time during which the humidifier is associated with particles of salt, before the composition reaches its freezing temperature, and lowering the temperature increases the viscosity of the composition, reducing the speed at which the particles collide with each other.

It should be understood that the optional ingredients, if any, can be introduced at a convenient stage of the process, such as those found in the absence of humidifier used or proposed to date. Thus, any temperature sensitive ingredient is preferably administered in a composition shortly before loading feeder and preferably at a temperature in which the limits of 10°C pour point.

In an alternative method of creating a solid kompoziziii soft consistency with the use of inorganic gelling, which usually consists of small particles, the ingredients of the composition, including oil, moisturizer, antiperspirant salt and gelling and any optional ingredient, is mixed together with high shearing forces and at the appropriate temperature, which may be equal to the ambient temperature (often in the region of 20-25°) or at elevated temperatures, usually up to 60 or 70°C to dispersing the components, consisting of particles throughout the mixture once mixed, the mixture will enter the container and it will cool or let her to cool to ambient temperature.

An alternative method that can be used for the manufacture of solid pencil, provides for the creation of a mixture containing oil, gel, moisturiser and antiperspirant, and intensive stirring of the mixture at a temperature below that at which melts the gel having the highest melting point; mixing is intense enough, dispersing the gel in the whole volume of oil to make the mixture quite mobile, so it can be entered in the form or distribution capacity.

Advantageously, because of its properties of PEG-humidifier can easily in order to enter in the associated production process, which does not use a humidifier without any detectable formation of solid particles and without the need to modify this method.

The composition obtained according to the present invention, suitable for distribution distribution of cosmetic containers for solid or solids soft consistency (semi-solid substances), depending on the specific case. Such distributing containers usually contain the spray, often round or oval in cross-section, which has an opening at one end through which is extruded composition, and the lift on the opposite, second end that can move toward the first end. The lift is fitted to the canister. Usually the first end cap is closed, the size of which is chosen so that it is conveniently sat on the outer surface of the container.

Hard pencils hole is a full cross-section of the canister, and for solids soft consistency hole is usually a dome pierced by numerous small apertures, usually round or oval, or a slit or slits, apertures or cracks often form a symmetrical structure and is usually approximately 8-35% of the area of the outer surface of the dome. The lift can move by putting one's finger in the bottle or by shimodate spindle with a threaded end and the aperture of the lift, the spindle is rotated by either sticking out of the wheel feed, or holding devices. Suitable distributing capacity for hard pencils are described, for example in US4232977, US4605330, WO09818695, WO09603899, WO09405180, WO09325113, WO09305678, EP1040445, US5997202, US5897263, US5496122, US5275496, US6598767, US6299369 or WO2002/03830. Examples of suitable distributing containers for soft or semi-solid substances contained in US4865231, US5000356, US6116803, US5961007, W9851185, EP0312165, WO0019860, EP0709041, EP858271, US5573341, US5725133, US5248213, US6398439 or US6450716.

The compositions of the present invention can be topically applied on the skin and, in particular, on underarm skin by extruding the composition in the form of a pencil above the top of the canister or compositions in the form of a solid substance with a smooth consistency to the dome of the applicator, depending on the circumstances, followed by friction on the surface of the skin, thus the skin surface is part of the composition. The action can be repeated until, until the user is satisfied that caused a sufficient amount of the composition; often distributing capacity is carried out by the armpit 3-8 times. The composition is usually applied soon after the armpit washed or shaved. Then the composition is left in place, traditionally, the time usually 5-24 hours, until it is washed away, usually using soap or shower gel and water, for example, caused by flan who do, loofah, sponge or even your fingers. If you want to suppress sweating, weight of antiperspirant active substances applied to the armpit, is often in the range of 0.15 to 0.5,

Specific embodiments of the present invention is described hereinafter by means of examples. A qualified technician can modify these options for implementation in accordance with the foregoing detailed description of the invention.

EXAMPLES

In the Examples below, hard or soft composition obtained using the following ingredients:

Examples 1-8 and Comparative Examples C9 and C10

In these examples, the antiperspirant compositions of the pencils were obtained in the following standard way. Oil, PEG, washing agents, together with any silicon dioxide and structural wax in proportions, are summarized below in Table 1, were mixed together and heated to approximately 85°C, to this point, the wax builders melted, forming a homogeneous mixture. The mixture was allowed to cool, while it continued to stir until the temp is the temperature reached about 70°C, after which he entered the antiperspirant, and then the flavoring. When the temperature of the mixture reached approximately 62/63°C, it was poured in the usual 50g boxes, equipped with a platform and mechanism for the rotation.

The resulting products-pencils were examined for the presence of solid particles with the help of an experienced group of experts in the following test procedure at ambient temperature in the laboratory (approximately 22°C) and evaluated using a 4-point scale.

The product was balanced with the environment in the laboratory, and the cap and the template (if distributing the tank was filled from the bottom) was removed from distributing capacity to push the dome of the pencil above the upper edge of the spray distribution capacity. Performed a visual assessment for the presence of solid particles, then the expert has put the index finger on one end of the naked dome and slowly held across the dome (with a speed of about 0.3-0.4 m/s) under the pressure of your finger to feel the roughness, indicating the physical presence of solid particles.

Scale solids

0. Visible agglomerates no; at the touch of the pencil is smooth, the friction during the finger is not felt, it indicates that any agglomerates are poorly connected and everything is easy to collapse napoliroma particles in contact with the finger.

1. Essentially visible agglomerates n is t; very weak sensations during the fingers point to the fact that almost all of the agglomerates to break easily napoliroma particles in contact with the finger.

2. A small amount of visible agglomerates; minor sensation while holding your finger point to the fact that the majority of the agglomerates to break easily napoliroma particles in contact with the finger.

3. May be a significant number of agglomerates; a feeling of unevenness in the application indicates that the agglomerates were firmly connected, and many or all of them split up to imperceptible particles in contact with the finger.

For each product are taken and averaged at least 4 and preferably at least 12 or 16 values. It is believed that the product does not contain solid particles, if the average score does not exceed 1.25.

Reference composition with index values 0 and 3 are prepared using the General process of Example 1, or not containing PEG to score 0 or replacement of glycerol on the PEG for grade 3, as summarized below in Table 1.

The results are summarized below in Table 2.

From Table 2 you can see that none of the products was not grainy, even if silicon dioxide was absent or present in low mass ratio to PEG-humidifier. This shows that silicon dioxide is not necessary to avoid the formation of solid particles. However, the products of C9 and C10 do not provide moisture on the 2nd day of the test on moisture.

Examples 11-23

The following compositions according to the present invention was obtained by cooking with the proportions of the ingredients listed below in Table 3. Pencils of Examples 15-20 are prepared in a standard way as in Examples 1-10. Pencils of Examples 11-14 prepare modified the way in which the amide or peptide amendment(Lee) was dissolved at a preliminary stage in the ISA by heating the mixture with stirring to about 90°C. the Remaining oil and any remaining amendment are mixed and heated to approximately 85°C. These two fractions are combined and the resulting mixture is then treated in the same way as in the standard method.

Examples 21 and 22 obtained as a result of changes to the standard method, in which a mixture containing all of the ingredients, which was formed at elevated temperature, cooled and subjected to mixing with a high effort shift during the cooling process, when the mixture has a freezing point in a calm state, so that the final product was in the form of a solid substance with a smooth consistency. Distribution capacity, in which the product then once ivali, is a convex dome-shaped applicator head having a large number of slits, through which the composition can be squeezed out due to the lifting platform. The product from Example 23 is prepared by mixing all ingredients at ambient temperature, heating the mixture to about 50°C and exposure to its mixing with the high-effort shift and subsequent spill mixture distribution capacity for solid antiperspirant soft consistency.

Example 24 and Comparative Example C25

In this Example, benefits for skin, when using a composition which is applied to the PEG, as demonstrated by a comparison of the elastic constants of the skin when processing under the same conditions a composition comprising PEG, and the same composition, in which the PEG was replaced with the same ratio of volatile silicone oil carrier, the composition described in Table 4.

Within 5 days of sample 0.2 g according to the invention and a standard composition was applied twice a day (only 1 time per day 5)to divide plots of 20 cm²on the Palmar surface of the forearm of the same arm 16 subjects before the test was conducted easy shave. Shortly after the second application on days 1-4 and 5 h after a single application on day 5 was measured elastic constant of the skin with Dermal Torque Meter^TMfrom Dia-Stron Ltd, Andover, UK, and the results are summarized below in Table 5.

In addition, daily measured transepidermal water loss with POM is using a Dermalab Evaporimeter from Cortex Technologies. Measurement at day 5 compared with the measurement at day 1, to determine whether there is any change in water loss through the epidermis, and average values for the subjects are summarized below in Table 6.

Compositions were as follows:

From Table 5 above, you may notice that the skin that was in contact with the antiperspirant composition containing separately entered PEG-humidifier, consistently showed a higher rate constants of elasticity than leather that has been treated in exactly the same manner as the composition not containing PEG. This shows that PEG increased the flexibility of the skin and at least partially counteracted the negative effect of the antiperspirant composition in the stratum corneum.

Table 6 shows that when using the product according to the invention the indicator TAPV better than when using the product comparison, which did not contain PEG8 and really +ve changes better than otsutstvie changes but even shows a decrease in the rate of water loss. This shows that the condition of the epidermis improved with the use of the product according to the invention, containing separately entered PEG-humidifier, even though it also contained about 25 wt.% astringent antiperspirant salt.

29-day test for irritation

In the following test a beneficial effect on the skin composition of Example 24 was performed to show that a decreased irritation experienced by users who have previously applied reference pencil containing AZAG, but not PEG.

29-day test for irritation held on 15 women participants aged 18-55 years for each of the test product or control. Two product or product plus control is usually tested at the same time involving 30 participants.

Testing procedure lasted 5 weeks, started on Monday; the first week was a phase of provocation and the subsequent four weeks - the recovery phase. During the test, participants were instructed to shave their armpits every night Wednesdays and Saturdays, using only disposable razors after using dampened with a mild soap, and then rinsed armpits water.

In phase provocation participants 4 times daily inflicted on both underarm antiperspirant pencil, having followed the s composition:

During the subsequent recovery phase, each participant put one product 4 times a day for the left armpit and the second product 4 times a day on the right armpit, the distribution between participants was randomized in order to achieve balance applied on the left and right hand under test and the second test or kontrolnaya. Pencils weekly weighed to confirm that the participants put a consistent amount on each hand. The skin condition of the participants were evaluated on Monday, Wednesday and Friday of each week. Measurement at Day 0 (initial value) was made on the first day (Monday) of the recovery phase immediately before the first application of the product. Day 29 was Monday, 4 weeks later.

The irritation experienced by participants, estimated trained analyst on a 5-point scale from 0 to 4 points according to the following evaluation criteria (the criteria you select depends on what symptoms detected:

Estimated scores for the composition of Example 24 were averaged; they are for each week in the Table 8 below.

From Table 8 it is seen that the product of example increasingly reduces irritation associated with the provocative product, showing that the pencil containing PEG-8, allows you to effectively avoid and reduce irritation resulting from shaving and similar activities that are typically performed in the armpits, and which continue to occur in the recovery phase.

Examples 26, 27 and Comparative Examples C28, C2

These Examples and Comparative Examples demonstrate the relative ability of PEG polymers of different average molecular weight moisturize the skin in 2 tests dehydration. Test substance and the resulting changes in hydration are shown in Table 9, and the results are depicted graphically in the drawing.

2-day test hydration is carried out as follows using at least 16 sections for each test substance, the age of the subjects were 18-55 years of age. The test uses 4 wt.% the solution potential of the humidifier in distilled water containing 0.5 wt.% DMDMH and thickened 14 wt.% the hydroxyethyl cellulose.

In the test used the Palmar surface of both forearms of each subject, 3 area on the forearm. In each set of tests for each plot measured initial hydration of the skin, immediately thereafter, they put the tested products, randomized tested on various parts of the body of the subjects. The second application of the same product produced after 5 h and the third application - even after 19 hours Hydration of the skin at each site was measured after 5 h at the end of the test, i.e. after 29 h after the first application. The difference between initial and final measurements for each set of averaged.

Hydration was measured using a Corneometer CM825 to the th available from Courage and Khazaka. Each test plot was a square 3×3, in which during each application inflicted 0.05 g of the product being tested. The measurement was made at a controlled temperature and humidity, 20°C and 50%under these conditions the patients were 15 min before was measured hydration. Patients were given instructions to avoid caffeine for 30 min before measuring skin hydration, and avoid washing and another dive forearms in water and apply moisturizing creams or lotions for 29 h tests.

From the Table and its graphical representation in the drawing it is seen that the moisturizing ability of PEG progressive decreases with increase of its molecular weight from PEG-8 (about 400) in Example 26 to higher values. In comparison s slight dehydration as compared to the initial measurement, and comparison 29 marked a much stronger reduction in the moisture. According to the prediction of positive hydration achievable when the molecular weight of the PEG is about 820 and below.

1. Without DNA antiperspirant or deodorant composition, which contains:
particles astringent antiperspirant salt;
20-90 wt.% oil carrier,
gelling the oil carrier and
humidifier-polyol,
where humidifier-polyol is 0.1-10% based on the weight of the composition, the polyethylene glycol has an average molecular weight of up to 820.

2. The composition according to claim 1, in which the average molecular weight of polyethylene glycol is from 150 to 620.

3. The composition according to claim 2, in which the average molecular weight of the polyethylene glycol is at least 190 or no more than 520.

4. The composition according to any one of claims 1, 2 or 3, which contains at least 0.5 to 7.5 wt.% poly (ethylene glycol).

5. The composition according to claim 4, containing 0.5-5 wt.% poly (ethylene glycol).

6. The composition according to any one of claims 1, 2 or 3, in which the particles astringent antiperspirant salts and polyethylene glycol are present in a weight ratio of from 4:1 to 40:1.

7. The composition according to claim 6, in which the particles astringent antiperspirant salts and polyethylene glycol are present in a mass ratio of 20:1.

8. The composition according to claim 7, in which the average molecular weight of polyethylene glycol is from 150 to 500.

9. The composition according to claim 1, in which pungent antiperspirant salt contains salt is a hydrochloride of aluminum and/or zirconium, it is not necessarily located in the complex.

10. The composition according to claim 9, in which pungent antiperspirant salt of t is possessing an activated hydrochloride aluminum or hydrochloride aluminum-zirconium, optional activated and/or in complex with the amino acid.

11. The composition according to claim 10, in which at least 99 wt.% astringent antiperspirant salt has a particle diameter less than 50 microns.

12. The composition according to claim 1, which contains from 40 to 90 wt.% oil carrier.

13. The composition according to item 12, which contains from 45 to 60 wt.% oil carrier.

14. The composition according to item 12, in which the oil-carrier comprises at least 20 wt.% volatile silicone oils.

15. The composition according to 14, in which the volatile silicone oil contains cyclomethicone.

16. The composition according to item 12, in which the oil-carrier contains ester oil and/or non-volatile essential oil.

17. The composition according to item 16, in which the ester oil contains aromatic ester oil, and non-volatile essential oil contains alkyl ether polypropylenglycol.

18. The composition according to item 16, in which the ester oil comprises at least 10 wt.% oil carrier and/or essential oil is up to 30 wt.% oil carrier.

19. The composition according to item 16, in which the oil-carrier contains ester oil and ether oil mass ratio of from 5:1 to 1:5.

20. The composition according to item 12, which includes a natural triglyceride oil.

21. The composition according to claim 1, which 100 parts of oil-carrier contains from 2 to 25 parts by weight of gelling.

22. HDMI is the information item 21, in which the gel contains wax.

23. The composition according to item 22, in which the wax gelling contains a linear fatty alcohol, if necessary in a mixture with wax, melting at a temperature of at least 75°C.

24. The composition according to item 23, in which a linear fatty alcohol contains stearyl alcohol.

25. The composition according to claim 1, which is converted into a gel by using polimernogo of gel-forming fiber.

26. The composition according A.25, in which the gel contains amide N-acylaminoacyl.

27. The composition according A.25, in which the gel is used in a mass ratio of from 2 to 10 parts per 100 wt. including oil carrier.

28. The composition according to item 12, in which the mass ratio of oil-carrier to the polyethylene glycol is at least 6:1 and/or less than 30:1.

29. The product containing the composition according to claim 1, which is distributing the vessel containing the canister, one end of which there is at least one hole through which the composition can be pushed, and on the opposite, second end has a lift, fitted to the inner surface of the container and are able to move to the first end.

30. Non-therapeutic method of suppressing perspiration or odor reduction of the body, including the stage of topical application to the skin the composition according to claim 1.