Method of treating nonspecific aerobic vaginitis

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed is method of treating nonspecific aerobic vaginitis by vagina sanitation with medication "Bioprost" in dose 1 suppository per night for 10 days. Method ensures complex therapeutic effect due to anti-inflammatory action of pumpkin seed oil, improving vigaina microecology, and thymol, which suppresses development of Gram-positive, Gram-negative bacteria, fungi, and possesses activity with respect to protozoa and herpes virus.

EFFECT: increase of treatment efficiency and consolidation of its results for long period due to restoration of normocenosis in vagina.

3 ex

 

The invention relates to medicine, namely gynecology, and can be used for aerobic treatment of nonspecific vaginitis.

There is a method of aerobic treatment of nonspecific vaginitis, based on the use of suppositories "Lexicon by intravaginal introduction on 1 suppository for the night within 10 days (Segolene, Behringen. The use of Lexicon for the treatment of infectious vaginitis / Gynecology, volume 6(1), 2004).

The prototype disadvantages: does not provide conservation treatment effect is accompanied by a significant number of relapses.

Effect: increase treatment efficiency and securing long-term results due to the recovery of normanize the vagina.

This result is achieved by applying as monotherapy combined drug with bacteriostatic and anti-inflammatory action "BIOPLAST", 1 candle intrawaginalno at night for 10 days.

The method is as follows: the patient is prescribed "BIOPLAST" on 1 suppository for the night intrawaginalno within 10 days. Before treatment exclude the presence of sexually transmitted diseases. "BIOPLAST" is a combination drug, produced in the form of suppositories, CJSC "Interform" Nizhny Novgorod, Russia, which consists m the words of pumpkin seeds, thymol and lipophilic suppozitornyj basis. This composition is selected in such a way that each ingredient has contributed to therapeutic effect of the drug. So, the pumpkin seed oil has anti-inflammatory effect and improves microecology in the vaginal biotope due to the large number of unsaturated fatty acids and antioxidants, and thymol inhibits the growth of gram-positive, gram-negative bacteria, fungi, has activity against the simplest and the herpes virus. The drug has been used previously in the treatment of chronic prostatitis.

For aerobic treatment of nonspecific vaginitis this medication is never used.

The positive effect of the proposed method is the rapid relief of symptoms: disappearance of discomfort, vaginal discharge, redness and swelling of the mucous membrane of the vagina, improving overall health. The value of the proposed method lies in the absence of side effects and complications, high efficiency. An important positive aspect of using this drug is an optimal correlation of price and quality.

Examples of specific performance

Example 1. Patient N., 37 years old, came with complaints of abnormal discharge from the genital tract and discomfort in the vagina. When viewed from lisita vagina - bright diffuse hyperemia, discharge abundant milk. Quantitative contents of leucocytes in a smear 50-70 in the field of view, abundant flora mixed. Bacteriological examination of vaginal discharge found Klebsiella terrigena 106CFU/ml, Streptococcus acidophylus 105CFU/ml, S.epidermidis 104CFU/ml On the basis of clinical and laboratory examination was diagnosed with non-specific aerobic vaginitis. The patient has a treatment: "BIOPLAST" 1 suppository into the vagina at night for 10 days. The use of the proposed drug has allowed to achieve cure after treatment. Seeded vaginal discharge disappeared many Gram (+) and Gram (-) organisms. Clinical examination (after 1 month) showed the absence of infectious and inflammatory changes in the vaginal pH were recorded within the normal range of 4.0. Pathogenic microflora is missing, Lactobacillus spp. in titles 106CFU/ml

Example 2. Patient H, 39 years old, came with complaints of liquid discharge from the genital tract discomfort in the vagina and dyspareunia. Considers herself a patient in the next 2-3 years, have addressed to the gynecologist, STI was not found. Exhibited the diagnosis of bacterial vaginosis were treated for a variety of antibiotic therapy, but the effect of the treatment was unstable. During the inspection noted: effusa hyperemia of the mucosa of the vulva and vagina; detachable homogeneous, load and with poor, yellowish color. The quantitative content of leukocytes in vaginal smear 40-80 in the field of view, clusters of polymorphic intermediate epithelium. Bacteriological examination of vaginal discharge is detected E. coli 104CFU/ml, Enterobacteriaceae 105CFU/ml, St. acidophylus 105CFU/ml, S.epidermidis 103CFU/ml On the basis of clinical and laboratory examination was diagnosed with non-specific aerobic vaginitis. The patient has a treatment: "BIOPLAST" 1 suppository into the vagina at night for 10 days. After the treatment of complaints and clinical and laboratory signs of disease were absent. Microscopy of vaginal smear leucocytes in a single field of vision, epithelial cells isolated flora of cocco-bacillary. In sowing the vaginal discharge is detected Enterococcus faecalis in titles 103CFU/ml of Lactobacillus spp. in titles 10 CFU/ml Repeated clinical examination (after 1 month) showed the absence of infectious and inflammatory changes in the vaginal pH were recorded within the normal range of 4.2. Bacteriological examination of vaginal discharge is detected Lactobacillus spp. in title 106CFU/ml

Example 3. Patient G., aged 26. Appealed to the obstetrician-gynecologist with complaints of abnormal discharge from the genital tract, discomf the RT in the vagina. These symptoms are disturbed in the course of one year. Have repeatedly asked for medical assistance to the gynecologist for the place of residence of sexually transmitted infections (STIs), was not found. In a smear on flora was observed elevated leukocytes. Was diagnosed with Colpitis unclear etiology. Prescribed therapy drugs group of the imidazole. The effect of the treatment was insignificant, and the symptoms returned. During the inspection were identified: focal hyperemia of the mucosa of the vulva and vagina; OTDELENIE homogeneous, gray-yellow, non-foamed PUR. The quantitative content of leukocytes in vaginal smear 15-30 in the field of view, clusters of squamous epithelium, abundant flora mixed. Bacteriological examination of vaginal discharge is detected Lactobacillus spp 102CFU/ml, S.aureus 106CFU/ml, St.acidophilus 105CFU/ml On the basis of clinical and laboratory examination was diagnosed with non-specific aerobic vaginitis. The patient has a treatment: "BIOPLAST" 1 suppository into the vagina at night for 10 days. After the treatment of complaints and clinical and laboratory signs of disease were absent. Microscopy of vaginal smear leucocytes 1-5 in the field of vision, epithelial cells isolated, bacillary flora. Seeded discovered Lactobacillus spp. in titles 105/sup> CFU/ml of Repeated clinical examination (after 1 month) showed the absence of infectious and inflammatory changes in the vagina. Bacteriological examination of vaginal discharge is detected Lactobacillus spp. in titles 107CFU/ml

The proposed method of treatment has been tested on 30 patients seeking medical help to the obstetrician-gynecologist.

A method of treating non-specific aerobic vaginitis by intravaginal administration of suppositories, characterized in that the use of the drug "BIOPLAST" 1 candle intrawaginalno at night for 10 days.



 

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