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A method of treating coronary heart disease, strokes voltage i-ii functional classes

A method of treating coronary heart disease, strokes voltage i-ii functional classes
IPC classes for russian patent A method of treating coronary heart disease, strokes voltage i-ii functional classes (RU 2177774):
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(57) Abstract:

The invention relates to medicine, cardiology. In the period of adaptation conducting vessels magnetic radiation cubital vein. Exercise lasermagnetic of vitamin E on biologically active points interscapular area in the zone C6-Th4 left. The pulse mode, the frequency of 1500 Hz, magnetic induction 20 MT. Conduct ultrasonic inhalation of hydrogen sulphide water. The concentration of hydrogen sulfide 30 mg/l Bromine baths begin to let go with a 6-day treatment course of 6 treatments. The method increases the remission period. 7 table.

The invention relates to medicine, namely cardiology, and can be used in medical practice for the treatment of ischemic heart disease I-II functional classes.

There is a method of treatment of ischemic heart disease by bromine balneotherapy [1] , giving an overall sedative effect only at the end of treatment.

The known method is not effective enough and is costly, the number of over-procedures - 8-14.

The objective of the invention is to increase physical performance and adaptive forces of the body, shortening the treatment time, lengthening the REMIS is East exposure cubital vein for 7 min, then lasermagnetic vitamin E for 5 min, acting on biologically active points interscapular area in the zone C6-Th4 left in pulsed mode 1500 Hz magnetic induction 20 MT at the flux density of radiation power of 54 mW/mm2followed by the ultrasonic inhalations sulphurous water in hydrogen sulfide concentration 30 mg/l at a flow rate of aerosol 5 l/min, the first 5 treatments every day, then every other day for a course of 10 treatments and iodide-bromine baths begin to release from the 6th day of treatment when I functional class through the first 2 day, next - every day, and when II functional class through the first 2 day, next 2 days in a row with a day break on a course of 6 treatments.

The advantage of the combined method is that it corrects the adaptation of the body systems IHD patients by successive stages of action of pulsed laser radiation (irradiation cubital vein) and lasermagnetic of vitamin E on certain corporeal biologically active points (BAP) in the first 5 days of stay of the patient at the resort, then alternating the specified method of lasermagnetic with total iodide-bromine baths p is the class of CHD, clinical and physiological variants of the disease, as well as pathogenetic orientation and therapeutic effect previously held magnetometry; subsequently in the medical complex includes ultrasound omagnichennogo aerosol hydrogen sulfide water, a mode of action which first developed taking into account the optimal combination and sequence of application used with modes lasermagnetic - and balneotherapy.

Particularly important in the recommended range of physical therapy in patients with coronary heart disease to achieve the desired therapeutic efficacy is the new preparatory course lasermagnetic vitamin E with advanced laser extravascular irradiation of blood with a powerful adaptogenic effect due to the synergistic effect of laser radiation, magnetic fields and vitamin E entered with lasermagnetic radiation, thereby creating conditions for effective use of iodine-bromine baths and ultrasound hydrogen sulfide water in a shorter time, thereby reducing treatment by 20%. This is the principal novelty of the recommended range of physical factors adaptogenic action. In addition, it is important and using the tion, increasing permeability of the skin by 2.5 times. The impact of low intensity factors, including medicines and mineral waters in small doses, at high efficiency in combination with other physical factors harmless, has no complications, economical from the standpoint of material and economic costs. In addition, vitamin E has not only adaptogenic properties, but also is a powerful antioxidant, and hydrogen sulfide water, which is important for multifactorial prevention of coronary heart disease.

The technique of vessels irradiation of blood is performed with use of therapeutic laser pulse "LT-1" and impaled on the emitter annular magnetic nozzle To 44-24-9,3 mm with magnetic induction in the cavity of the window of the applicator 50 MT from the kit MA-1-001 for laser and biophysical instruments. Vessels irradiation is exposed to the blood flowing through the cubital Vienna left or right hand.

The patient is in a supine position on the couch, his arms folded in the horizontal plane of the body at an angle thereto in the 90oand sits on the table inner surface upwards. Laser emitter contact is established, perpendicular to the arm and is fixed in e is of the laser pulse, the pulse frequency of 1,500 Hz, a pulse duration of the radiation 100 NS. The exposure time in auto mode 7 minutes, the density of the radiation power 8,93 mW/cm2in the plane of the exit window of the applicator at normal temperature. Magnetic induction in the plane of the window 50 MT.

Immediately vessels after exposure to the patient spend lasermagnetic vitamin E. Methods of lasermagnetic vitamin E is made with the help of the emitter ALT "Pattern-AND-2K" mounted annular magnetic nozzle To the-28-9-5.6 mm kit MN-1-001.

Lasermagnetic vitamin E is performed on the area of the skin, bounded by the vertical lines passing through the inner edge of the left scapula and the spinous processes of the spine and horizontal lines passing through VI neck and IV of the thoracic vertebrae. The skin of this zone is treated once in a 30% solution of Dimexidum as a penetrant. After 15 minutes of exposure to this area lay on a strip of size 200 cm2filter paper soaked in 1 ml of 5% oil solution of vitamin E.

The patient sitting, his head slightly tilted forward. The emitter ALT "Pattern And respective movements of the emitter carry out laser processing surface within the strip at a speed of 2 cm/S. The pressure of the emitter on the surface of the body of the individual and should provide a smooth sliding without the formation of folds on the strip. The annular magnetic nozzle To 28-9-5,6 mm, 20 MT induction. The mode of emission of the laser pulse. The pulse repetition frequency of 1,500 Hz, a pulse duration of laser radiation at 0.5 with not less than 7108the exposure time in continuous mode 300 s; the density of the radiation power of 54 mW/mm2in the plane of the exit window of the applicator at normal temperature. Course of 5 treatments daily from the second day of stay at the resort. Subsequent 5 - a day, a total of 10 treatments.

2 hours after lasermagnetic vitamin E conduct ultrasonic inhalation of hydrogen sulphide water. Ultrasonic inhalations omagnichennogo aerosol hydrogen sulfide water are performed using a commercially available ultrasonic nebulizer TUR USI 50, the annular magnetic attachment To the-44-24-9.3 mm kit MN-1-001 for laser biophysical devices.

The technique is performed with the use of vysokodispersnyh aerosols serviceregistered mineral water. Procedure release in a separate room with a permanent supply and exhaust blower adjust the Oia level of hydrogen sulfide in mineral water. To obtain vysokodispersnyh aerosols use serviceregistered mineral water containing H2S 30 mg/l Prepared mineral water to the desired concentration ex temporae, immediately before the leave procedures with mandatory laboratory control of imported from the source of hydrogen sulfide water of high concentration (150 mg/l to 200 mg/l). To transport this water use airtight 0.5 liters capacity made of dark glass, which should be permanently closed to provide minimum contact between water and air and to prevent the reduction of H2S due to oxidation. For cultivation of this water to the desired concentration used degassed water, i.e. water, which due to periodic moderate heat (not more than 36o(C) in the uncovered cylindrical vessel and regular stirring of the contents of H2S drops to a level that is practically not used in the calculation. Water degassing is taken from the same wells with the goal of preserving the identity of the salt composition. A ready solution to obtain aerosol should be stored in a dark glass jar with a glass stopper.

Design features ultrasonic nebulizer TUR USI 50 give the blowing procedure parameters:
1. The content of H2S in the mineral water 30 mg/l
2. The feed rate of the spray 5 l/min
3. The time duration inhalation aerosol for 2 minutes
4. The consumption of mineral water and 5 ml of 1 inhalation
5. In the course of 10 treatments.

Iodine-bromine baths are appointed with 6-day stay in the clinic at a temperature of 36oWith duration 10-12-15-20 minutes, 6 course, the first two baths a day, the next 4 daily (for patients with functional class I, two days in a row with a day's break for II functional class).

Preparatory five-day course magnetic impact and ultrasonic inhalations sulphurous water in differentiated parameters depending on the severity of the disease create preconditions for the development of adaptation of the organism.

Example 1. Patient K. , 46 years old, was treated in the cardiology clinic with 03.09.98, 24.09.98, with a diagnosis of CHD. Angina, FC I, N0.

Upon receipt complained of intermittent pressing pain in region of heart, occurring against a background of emotional stress, irritability, insomnia, fatigue, anxiety, instability nestroy developed normally. Borders of the heart is not changed, the heart rate of 78 beats per minute, satisfactory quality, BP= 120/80 mm RT. Art. (D= S) heart sounds rhythmic, muted, accent II tone of the aorta. In the lungs - vesicular breathing. The abdomen is soft, painless, the liver is not enlarged. Symptom of Pasternack negative on both sides. In the Romberg sustainable, tremor of eyelids, fingers, palanisamy sample performs correctly.

These additional studies:
General an. blood: b - 161 g/l, er. - 5,01012/l, 1 - 5,4109/l, ESR - 6 mm/h, p - 2%, 47%, e - 2%, m - 7%, l - 42%. Response adaptation = 0,3 (Garkavi L. H.) reaction of stress.

ECG - reduction processes repolarization of the myocardium of the left ventricle.

VEM - tolerance to physical load is moderately low, the achieved capacity is 108 watts, normostenichesky type of reaction of the cardiovascular system to physical activity.

Biochemical blood test: a patient presents minor violations lipoproteina metabolism-serum catalase - 48.7 µkat/l, ceruloplasmin - 0,272 g/l, total lipids of 3.14 g/l, triglycerides - 1.57 mmol/l, total cholesterol - 7,21 mmol/l, cholesterol-alpha-lipoproteins is 1.86 mmol/l, the index of atherogenic - 2,88, beta-lipoproteins - 6.2 g/l, que is pidof - 14.6 nmol/mg lipid.

From the second day of stay of the patient at the resort assigned to the treatment by the proposed method (table 7) for I functional class. The adjustment period has passed, the patient calm. By the fifth day of stay in hospital he declined neurotic complaints, improved sleep, by the tenth day - stopped the pain in the heart area, normalized sleep.

As a result of treatment by the end of the second week the patient's condition improved significantly; no pain in the heart, stopped headache, normalized sleep, increased tolerance to physical activity.

At follow-up, the following data:
Complete blood count: b - 153,5 g/l, er. - 4,91012/l, 1 - 5,4109/l, ESR - 3 mm/h, p - 2% - 49% e - 3%, m - 7%, l - 38%. The reaction adapt Garkavi - 0,7 (reaction peaceful activation).

ECG - improve trophism of the myocardium of the left ventricle.

VEM is the increased tolerance to physical activity, achieved capacity -180 W, a 66% increase compared with the original data.

Biochemical blood analysis: serum catalase - 37.7 µkat/l ceruloplasmin - 0,296 g/l, total lipids - the 6.06 g/l, triglycerides - of 1.30 mmol shall ipoprotein - 5.6 g/l, diene conjugates of lipid - 2,64, malonic dialdehyde red - 44,6 nmol/ml er. mass, malonic dialdehyde lipid - 14.0 nmol/mg lipid.

Thus, the use of this technique showed clear adaptogenic, sedative, anesthetic effects: withdrawal heart pain, headaches, improving processes kardeogemodyinamiki, physical and emotional stability, improved lipoproteina metabolism (reduction of the most atherogenic fractions of lipid metabolism, normalization of lipid peroxidation and activation of antioxidant protection. The transition response of stress in a calm reaction activation (according to the reactions adaptation) says about the adequacy of the impact of natural and preformed physical factors on the patient's body.

Example 2. Patient Z. , 60 years of age, was treated in the clinic with 20.09.98, 01.10.98, with a diagnosis of CHD. Angina, FC II, N0-1. Arterial hypertension.

Upon receipt complained of intermittent pressing pain in region of heart arising on a background of physical and emotional stress, shortness of breath when climbing to the third floor, periodic headache disorders: a proper physique, the subcutaneous fat layer is moderately developed. Borders of the heart extended to the left by 0.5 cm, pulse - 74 beats. /min, satisfactory qualities, AD= 130/70 mm RT. Art. (D= S). Heart sounds rhythmic, muted, accent II tone of the aorta. In the lungs vesicular breathing, wheezing no. The abdomen is soft, painless, the liver is not enlarged. Symptom of Pasternack negative on both sides. In the pose of Roberge sustainable, tremor of the fingers, eyelids, finger-nasal sample performs correctly.

Complete blood count: b is 125.8 g/l, er. - 4,61012/l, 1 - 5,7109/l, ESR - 15 mm/h, p - 2%, 46%, and e - 1%, m - 12%, l - 39%. The reaction adapt Garkavi - 0,9 (reaction high activation).

ECG violation of intraventricular conduction on the right pedicle isthmus of GIS, the reduction of repolarization of the myocardium.

VEM - tolerance to physical load is reduced, the achieved capacity is 66 watts, register signs of CHD, FC II-III, normostenichesky type of reaction to physical activity.

Biochemical blood analysis: serum catalase - 71.7 µkat/l ceruloplasmin - 0,328 g/l, Total lipids 6,09 g/l, triglycerides by 1.68 mmol/l, total cholesterol - to 8.45 mmol/l, cholesterin-alpha-lipoproteins - 1,90 mmol/l, the atherogenic index is 3.45, beta-lipoproteins - 7.20 g/l, di is epidem - 9.28 are nmol/mg of lipids (there has been a violation of lipid metabolism and the processes of lipid peroxidation with significant voltage antioxidant protection).

From the second day of stay of the patient at the resort she was assigned to the treatment by the proposed method (table 7) for II functional class. The adjustment period has passed, the patient calm. By the fifth day of stay in hospital the patient's condition has improved: reduced weakness, fatigue, shortness of breath, improved sleep, by the tenth day stopped the pain in the heart area, normalized sleep, significantly decreased shortness of breath, HELL fluctuated within normal limits.

At follow-up, the following data:
Complete blood count: b - 126 g/l, er. - 4,21012/l, 1 - 8,05109/l, ESR -10 mm/h, p - 1%, 53%, e - 2%, m - 7%, l - 37%. The reaction adapt Garkavi - 0,7 (reaction peaceful activation).

ECG - improve trophism of the myocardium of the left ventricle.

VEM is the increased tolerance to physical activity, achieved capacity - 91 W, which is 38% more in comparison with the original data.

Biochemical blood analysis: serum catalase - 39.4 µkat/l ceruloplasmin - 0,403 g/l, total lipids 3.80 g/l, triglycerides - of 1.09 mmol/l, obaidi - 6.60 g/l, diene conjugates of lipids of 3.56, malonic dialdehyde erythrocyte - 35,0 nmol/MD er. mass, malonic dialdehyde lipid - of 9.21 nmol/mg lipid.

Thus, the use of this technique showed clear adaptogenic, sedative, anesthetic effects: withdrawal heart pain, headaches, improving processes kardeogemodyinamiki, physical and emotional stability, improved lipoproteina metabolism (reduction of the most atherogenic fractions of lipid metabolism, normalization of lipid peroxidation and increasing antioxidant protection. HELL during the whole period of treatment was consistently normal.

Just surveyed and treated 76 patients in three groups: I group and 40 patients received treatment by the proposed method - patients with ischemic heart disease, angina, I-II functional classes, without arrhythmias, circulatory failure is not above the I century , with risk factors - hypertension, hypercholesterolemia, psychological stress, impaired reactions of adaptation. Group II - 36 patients with coronary artery disease, angina, I-II functional classes, without rhythm disorders, deficiency of blood is the third voltage, violation reactions adaptation - received treatment total iodine-bromine baths (prototype).

The most frequent subjective manifestations of disease in both groups had pain in my heart constricting or whining character with irradiation to the left arm, below the shoulder blade arising from physical or emotional stress, palpitations, shortness of breath while climbing uphill or upstairs. In addition, almost all patients had expressed various degrees of sleep disturbance, irritability, fatigue, unexplained feelings of fear, anxiety.

In the analysis of subjective symptoms during treatment were observed improvement in all groups observed patients. When the one-way dynamics of the subjective state in the first group there was a marked analgesic effect: removal of heart pain, palpitations, headaches in the middle of the treatment; observed and a clear anxiolytic effect disappeared irritability, fatigue, sleep disturbance (table 1), in group II positive effect was observed only at the end of treatment.

According to table 1 notes a sufficiently high efficiency of treatment in group I (subjective symptoms) compared with II LASS="ptx2">

One of the objectives of this work was to study adaptive responses CHD patients in the treatment process using a variety of medical facilities. Adaptive reactions were studied by L. Garkavi H. (the ratio of lymphocytes to segmental neutrophils) and is estimated by the value of this index (table 2).

Analysis of the obtained data testifies to the one-way dynamics of reactions. There is also a clear transition to the most favorable reaction -"quiet" activation by reducing the number of patients with increased activation" and "stress". The development of favorable prognostic against adaptive reactions "calm activation" and "training" is more conducive to complex iodide-bromine baths, magnetic effects, ultrasonic inhalations sulphurous waters, to a lesser extent medical complex, accept patients of group II. Obviously, iodide-bromine baths themselves without augmentation from other physical factors have a lesser degree the General sedative effect on the body.

Thus, the improvement of the subjective condition, emotional stability during activation adaptation of reactions is th complex and adequate choice in the multifactorial prevention of coronary heart disease.

Comparative performance assessment exercise samples of patients with coronary heart disease under the effect of the combined treatment showed a high efficiency in all groups surveyed, but more significant in group I: the amount of work done in this group is significantly higher than in group II patients, showing a significant increase in tolerance to physical stress (the amount of work done in group I increased 13% from the original, and the second group - 7.2%). The frequency of cardiac contractions at the level of achievement of the maximum tolerated load remained practically unchanged as diastolic blood pressure. Dynamics of dual works of systolic and diastolic pressures are most pronounced in group I who proposed methodology and less significant in group II, which allows to consider the use of only iodine-bromine baths less favorable than for physical health (table 3. ).

Under the influence of the treatment with the use of various medical complexes in patients with positive dynamics of lipid metabolism by lowering cholesterol, triglycerides, beta-lipoproteins and increase 1-cholesterol and with whom the SCP patients took 1st medical complex, which included iodide-bromine baths, lasermagnetic vitamin E and ultrasonic inhalation of hydrogen sulphide water. When using therapeutic complex prototype of the studied parameters in orientation had a similar dynamics of lipid metabolism, but it is in most cases statistically only had a high tendency to significance (table 4, 5)
From the tables it is seen that the most effective is the complex using lasermagnetic of vitamin E on the background of the iodine-bromine baths and ultrasonic inhalation of hydrogen sulphide water.

In the course of the research it is established that the proposed complex treatment causes more favorable and soft adaptation shifts and distinct positive changes in the biochemical indices of the blood, reducing the most atherogenic fractions lipoproteina metabolism, lipid peroxidation and increasing antioxidant protection of blood. It is noted increase physical performance by 15-20%, improvement of the processes of adaptation in patients with the transition to the most favorable reactions "activation" (Garkavi L. H. ),
The comparative evaluation of two therapeutic is, is pokazateli lipoproteina metabolism, hemostasis and immune marked by rather high efficiency of the proposed method of treatment, due to its differentiated choice of multifactorial prevention and treatment of this group (table 6. )
When evaluating the effectiveness should be taken into account and the timing of its occurrence. Generally, improvement in the subjective symptoms, reactions adaptation and emotional stability observed in 5-7 day hospital stay in patients of group I, to the end of treatment in group II. Improvement of objective data in group I notes to 15-20 day of treatment, in group II - to 24 days.

When the total therapeutic efficiency up to 95% in a shorter time (15-20 days) observed a significant economic impact due to the shortening of the course total bath ( 6) and a smaller consumption of mineral water in ultrasonic, inhalati (30 ml).

The effect is 9-15 months after treatment in patients of I group with fewer exacerbation 3.84 times.

Sources of information
1. Guidance for doctors for the treatment of patients in the resort of Sochi. /Under the editorship of Dr. med. Sciences Romanova N. That is , Sochi, 1974 , S. 54-59, 167.

The method of treatment otlichayushiesya fact, in the period of adaptation conducting vessels magnetic radiation cubital vein for 7 min, then lasermagnetic vitamin E for 5 min, acting on biologically active points interscapular area in the zone C6-Th4 left in pulsed mode 1500 Hz magnetic induction 20 MT, when the flux density of radiation power of 54 mW/mm2, followed by ultrasonic inhalations sulphurous water in hydrogen sulfide concentration 30 mg/l, at a flow rate of aerosol 5 l/min, the first 5 treatments daily, then every other day, a course of 10 treatments and iodide-bromine baths begin to release from the 6th day of treatment when I functional class through the first 2 day, next 2 days in a row with a day break on a course of 6 treatments.

 

 

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