Method of producing α-methylsubstituted carbonyl compounds

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing α-methylsubstituted carbonyl compounds of gthe eneral formula R1-CO-CR3(CH3)-R2, where: R1 and R2-hydrogen H or a linear or branched alkyl radical containing 1 to 12 carbon atoms, R3-H or CH3 radical, which are feedstock for producing a number of chemical products and drugs, are used as solvents and can be used as a base for producing high-octane motor fuel components. Method involves conversion of initial gas-vapour mixture of carbonyl compound selected from compounds of general formula R4-CO-CHR5-R6, where: R4 and R6-H or a linear or branched alkyl radical containing 1 to 9 carbon atoms, R5-H or CH3 radical, and methanol using copper-containing catalyst when introducing in initial reaction mix of hydrogen.

EFFECT: proposed method allows to increase the catalyst interregeneration runtime in several times, and consequently, the amount of product obtained per unit volume of the reactor.

3 cl, 1 tbl, 6 ex

 



 

Same patents:

FIELD: chemistry.

SUBSTANCE: one of method versions is carried out in presence of catalyst with strong acidity in one or several reaction zones with further separation of reaction mixture by means of rectification and possibly partial recycling into reaction zone(s) of one or several components of reaction mixture. Decomposition is carried out in presence of inert easily-boiling solvent, which contains mainly hydrocarbons, whose boiling temperature is lower than 70°C, preferably lower than 40°C, but not lower than minus 1°C, which is partially evaporated directly from reaction zone(s) and partially distilled from obtained reaction mixture, is in liquid state returned to reaction zone(s) with supporting in it (them) temperature from 1 to 70°C, preferably from 10 to 45°C. Second method version is carried out in presence of catalyst with strong acidity in one or several reaction zones with further separation of reaction mixture by means of rectification. Applied is easily-boiling solvent, which after separation from reaction mixture, possibly with part of ketone, is recycled into reaction zone(s), and sulfocationite catalyst in H+ form, resistant in liquid media, containing alkylaromatic hydroperoxides, ketones, phenol and hydrocarbons in large amount, at temperatures up to 70°C, in fine-grain or coarse-grain form, possibly, in form of mass-exchange filling with size from 1.5 to 25 mm.

EFFECT: obtaining phenol and ketones without formation of large amount of by-products and resins and practically without equipment corrosion.

14 cl, 1 dwg, 6 ex

FIELD: industrial organic synthesis.

SUBSTANCE: in presence of a process for production of methyl ethyl ketone widely applicable in petroleum processing and petrochemical industries at oil dewaxing and paraffin deoiling plants, in varnish-and-paint industry to produce polyurethane coatings, in wood processing industry to produce a variety of glues, in industrial rubber article industry, in perfumery, and in other areas. Process comprises 2-butanol/hydrogen peroxide reaction conducted at 20-100°C and butanol/peroxide molar ratio (1.0-13.0):1 on titanium silicate catalyst having MFI, MEL, or beta zeolite topology and containing 0.1 to 9.5% titanium, content of catalyst ranging from 0.01 to 20% based on the total weight of reaction medium. Thus formed methyl ethyl ketone is isolated from reaction medium via rectification in the form of azeotrope with water while unreacted 2-butanol with admixture of water is recycled to synthesis stage. Methyl ethyl ketone/water azeotrope is separated via extraction with organic solvent as extractant at extractant-to-azeotrope ratio (0.5-10):1 and number of extraction steps from 1 to 10. Extract is separated via rectification or distillation processes to recover commercial methyl ethyl ketone while returning extractant to separation stage.

EFFECT: increased yield of methyl ethyl ketone and reduced power consumption.

2 cl, 1 tbl

FIELD: organic chemistry, chemical technology.

SUBSTANCE: invention relates to a method for synthesis of 3-bromoadamantyl-1-alkyl(aryl)-ketones of the general formula: , wherein that can be used as intermediate substances for synthesis of some biologically active compounds. Method involves interaction of 1,3-dehydroadamantane with α-bromoketones of the following order: α-bromoacetone, α-bromoacetophenone, α-bromocyclohexanone in the mole ratio of reagents = 1:(2-3), respectively, in absolute diethyl ether medium, at temperature 34-40°C for 3-4 h. Method provides preparing the claimed compounds with high yield.

EFFECT: improved method of synthesis.

3 ex

FIELD: main organic synthesis.

SUBSTANCE: proposed method is used for production of ketones, for example dimethyl ketone (CH3COCH3), methyl ethyl ketone (CH3COC2H5) by direct catalytic oxidation of respective alkenes, for example propylene, n-butenes, as well as catalysts for realization of this method. Oxidation of alkenes is performed in the presence of metallocomplex catalysts containing organic component where nitrogen oxide (I) is used as oxidant. Used for process is catalyst on base of peroxopolyoxo metallate complexes of terakis (oxo diperoxo metallate)-phosphate (3-) together with quaternary ammonium cationes having formula Q3{PO4[MeO(O2)2]4}, where Me-Mo, W,V; Q3 is quaternary ammonium catione containing alkyl chains C4-C8 or N-hexadecyl pyridinium.

EFFECT: enhanced selectivity of process.

10 cl, 14 ex

FIELD: industrial organic synthesis and catalysts.

SUBSTANCE: invention relates to a methyl ethyl ketone production process via catalytic oxidation of n-butenes with oxygen and/or oxygen-containing gas. Catalyst is based on (i) palladium stabilized with complexing ligand and (ii) heteropolyacid and/or its acid salts, in particular molybdo-vanado-phosphoric heteropolyacid having following composition: H11P4Mo18V7O87 and/or acid salt Na1.2H9.3Mo18V7O87, said complexing ligand being notably phthalocyanine ligand. Catalyst is regenerated by making it interact with oxygen and/or oxygen-containing gas at 140-190°C and oxygen pressure 1 to 10 excessive atmospheres. Oxidation of n-butenes is conducted continuously in two-stage mode at 15 to 90°C in presence of above-defined catalyst.

EFFECT: enhanced process efficiency due to increased stability of catalyst resulting in considerably increased productivity and selectivity.

7 cl, 1 dwg, 3 tbl, 8 ex

The invention relates to the field of organic synthesis, namely the method of producing ethyl ketone by catalytic oxidation of n-butenes with oxygen, and the catalyst for its implementation

The invention relates to a method for producing methyl ethyl ketone, which is widely used as a solvent perchlorovinyl, nitrocellulose lacquers and adhesives

The invention relates to the production of lower ketones liquid-phase dehydrogenation of secondary alcohols in the presence of a fixed catalyst - Nickel metal or activated hydrogen Nickel metal or Nickel on the carrier in the environment paraffins C12-C20that process is used as solvent, the drying means, the environment for the activation of the catalyst and carrier

FIELD: chemistry.

SUBSTANCE: claimed invention relates to field of chemistry of ketones, in particular, to method of preparing catalyst for obtaining 3-acetylheptane-2,6-dione and to method of obtaining 3-acetylheptane-2,6-dione with application of obtained catalyst. Described are: method of preparing microdimensional catalyst for obtaining 3-acetylheptane-2,6-dione, which consists in dissolution of cerium chloride hydrate of formula CeCl3×7H2O in methyl alcohol with further removal of solvent by its evaporation for 1 hour at temperature 90°C and heating residue for 1.5 hour at temperature 150°C, and method of obtaining 3-acetylheptane-2,6-dione by interaction of acetylacetone with methylvinylketone in presence of obtained catalyst, process being carried out with molar ratio acetylacetone: methylvinylketone: catalyst in terms of CeCl3×7H2O equal 1:1:0.1-0.2.

EFFECT: increased output of 3-acetylheptane-2,6-dione to 76-87% due to application of obtained catalyst, nearly 3-fold reduction of amount of used catalyst, carrying out process of obtaining 3-acetylheptane-2,6-dione without solvent, as well as reduction of time of process carrying out, which makes process cheaper and reduces ecological load onto environment.

2 cl, 4 ex

FIELD: chemistry.

SUBSTANCE: invention pertains to the method of oxidation of hydrocarbons using oxygen in trifluoroacetic acid and can be used particularly for oxidation of alkanes, cycloalkanes, alkylaromatic hydrocarbons, alkenes, cycloalkenes. The method involves saturation of trifluoroacetic acid with oxygen, after which, the initial hydrocarbon is added to the obtained reaction medium and is kept until depletion of bound oxygen with obtaining the corresponding oxygen containing compound.

EFFECT: invention allows carrying out a process of selective partial catalytic oxidation of hydrocarbons with obtaining different oxygen containing organic compounds without use of high temperature and traditional catalyst systems based on transition metals.

1 tbl, 5 ex

FIELD: organic chemistry, chemical chemistry.

SUBSTANCE: invention relates to a method for synthesis of compound of the formula (I): . Method involves interaction of compound of the formula (II)

with compound of the formula (III) in the presence of a catalyst chosen from cationic complexes of bivalent ruthenium and polar organic solvent. Also, invention relates to a novel compound of the formula (I) that is used in synthesis of phyton and vitamin E, and to a method for synthesis of phyton also.

EFFECT: improved method of synthesis.

20 cl, 3 ex

FIELD: main organic synthesis.

SUBSTANCE: proposed method is used for production of ketones, for example dimethyl ketone (CH3COCH3), methyl ethyl ketone (CH3COC2H5) by direct catalytic oxidation of respective alkenes, for example propylene, n-butenes, as well as catalysts for realization of this method. Oxidation of alkenes is performed in the presence of metallocomplex catalysts containing organic component where nitrogen oxide (I) is used as oxidant. Used for process is catalyst on base of peroxopolyoxo metallate complexes of terakis (oxo diperoxo metallate)-phosphate (3-) together with quaternary ammonium cationes having formula Q3{PO4[MeO(O2)2]4}, where Me-Mo, W,V; Q3 is quaternary ammonium catione containing alkyl chains C4-C8 or N-hexadecyl pyridinium.

EFFECT: enhanced selectivity of process.

10 cl, 14 ex

FIELD: organic chemistry, chemical technology.

SUBSTANCE: invention relates to a method for synthesis of saturated ketones from corresponding unsaturated compounds (enones) using sodium dithionite as a reducing agent in an aqueous-organic medium based on surface-active substances. Method is carried out by reduction of unsaturated ketones of the general formula (I): to saturated ketones of the general formula (II): wherein R means lower alkyl or phenyl; R1 means hydrogen atom, (C3-C6)-alkyl or phenyl; R2 means alkyl or (C3-C6)-cycloalkyl, or alkyl substitutes R1 and R2 can form in common 5-6-membered carbocycle; R3 means hydrogen atom. The reduction reaction is carried out with sodium dithionite in an aqueous-organic microemulsion medium containing a surface-active substance as a solubilizing agent, aliphatic alcohols of normal or branched structure with number of carbon atoms from 3 to 5 as a co-solubilizing agent, and water in the mole ratio = 1:(4-6):(200-400), respectively, in the presence of electrolyte. The end substance is isolated by extraction. Method involves using anionic or cationic surface-active substances of the general formula: CnH2n+1X wherein X means -OSO3M, -SO3M, -COOM, -NMe3Hlg (wherein M means alkaline metal or ammonium; Hlg means halide); n = 11-16. Alkaline metal carbonates or hydrocarbonates are used as an electrolyte. Invention provides using inexpensive available reducing agent, simplifying process, enhancing purity and yield of the end substance.

EFFECT: improved method of synthesis.

3 cl, 9 ex

FIELD: organic chemistry, chemical technology.

SUBSTANCE: invention relates to a method for oxidizing liquid hydrocarbons in barrier discharge carried out in the bubble reactor with mixtures of oxygen with helium, argon or nitrogen. Method involves using helium, argon and nitrogen taken in the amount 20-80%. The oxidation process is carried out in the presence of solid additives wherein aluminum, nickel, molybdenum, copper oxides or zeolite catalyst ZSM-5 comprising 1.2% of Fe is used. Method provides reducing energy consumptions for oxidation of the parent hydrocarbon in the barrier discharge.

EFFECT: improved oxidizing method.

3 cl, 2 tbl, 10 ex

The invention relates to a method for producing carbonyl compounds with the number of atoms2-C40

The invention relates to the field of synthesis of terpenoid ketones, and in particular to an improved method of obtaining Fiona, which can be used in the synthesis of vitamins E and K

The invention relates to the field of production of oxygen-containing organic compounds, ketones, unsaturated alcohols and possibly aldehydes by isomerization WITH5-epoxides in the presence of a homogeneous catalyst
The invention relates to a method for producing 1-phenyl-1-(alkyl)phenylacetone, which is an intermediate for obtaining rodenticide preparations of 2-(-phenyl--(alkyl)phenylacetyl)indandione-1,3, in particular ethylbenzene(alkyl R = C2H5and izinduna (alkyl R = ISO-C3H7) used for the control of rodents

FIELD: chemistry.

SUBSTANCE: present invention relates to a method of recycling 2-chloro-1-phenylethanol-1, an irritant substance, in order to obtain a highly effective rodenticide - 2,2-bis(2-oxo-2-phenylethoxy)indandione-1,3 which can be used in agriculture for rodent control. The method involves reacting 2-chloro-1-phenylethanol-1 with ninhydrin in an acetone medium in the presence of potassium carbonate. As a rule, the reaction is carried out at 50-60°C for 4-5 hours.

EFFECT: increased efficiency of recycling 2-chloro-1-phenylethanol-1.

2 cl, 3 tbl, 1 dwg, 1 ex

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