Method for controlling functional state of patient's body

FIELD: medicine.

SUBSTANCE: invention refers to medicine, functional diagnostics and can be used for preclinical, predoctoral examination, assessment of the functional state of body organs and systems, and pre-diagnosis. The method involves measuring electrical conductivity (EC) of 24 representing points of 12 symmetrical meridians, determining an arithmetic mean (AM) value of these measurements and specifying a corridor of permissible values for this patient, to which the derived values are compared in order to assess the functional state of the patient's body. That involves using the following criteria: a ratio of total ECs of Yin meridian points to total ECs of Yang meridian points, a ratio of total ECs of arm points to total ECs of leg points, a ratio of total ECs of left-side points to total ECs of right-side points. ECs are measured at voltages 5V, and/or 9V, and/or 12V. If the measurements are taken at 9V, the measured ECs are re-calculated by formula: I new=9/(29/I measured-0.1)*Coeff, (I); if the measurement process is performed at 12V, the measured values are re-calculated by formula: I new=9/(29/I measured-0.1)*Coeff, (I); and at 5V: I new=1 measured*Coeff, (III), wherein in (I), (II) and (III) respectively: I new is the re-calculated EC; I measured is the measured EC; Coeff is a correction coefficient taking into account a meridian conductivity heterogeneity. The re-calculated values are transformed into adjusted ones by formula: I adjusted=I new/I mean, wherein: I adjusted is the adjusted EC; I new is the non-adjusted re-calculated EC; I mean is the arithmetic mean value of all the 24 measurements. That is followed by delimiting an individual normal corridor for this patient depending on the preset diagnostic sensitivity S and a width of corridor of the permissible EC values Wpv. The Wpv represents a range of EC values measured in this patient, whereas the diagnostic sensitivity S is specified depending on selecting the patients with a certain disease. Delimiting the individual normal corridor for this patient is ensured by measuring intermediate coefficients for lower Kl and upper Ku corridor limits respectively: Kl=1-(1-S)*Wpv/2.1 and Ku=1+(1-Kl)*1.1. Lower L and upper U limits of the individual normal corridor are determined: L=Kl* I mean and U=Ku* I mean. That is followed by comparing I adjusted to the derived limits of the individual normal corridor.

EFFECT: method provides high accuracy of the individual diagnosis.

4 tbl, 2 ex

 

The invention relates to medicine, particularly to functional diagnostics, and can be used for preclinical pre-medical examination of patients, determine the functional state of organs and systems of the body and setting the preliminary diagnosis, followed by its refinement and therapy.

The fact that the diagnosis of various human diseases can be put not only on the basis of organic changes in the body, which are revealed when carrying out various clinical examinations or clarifying the patient's complaints, but also on the basis of functional disorders, was discovered by R. Dubois in 1857. Then the functional dependence of certain points on the body with the body systems become involved in G. A. Zakhar'in - 1883; I. R. Tarkhanov - 1889; göd - 1898; Y. V. chagovets - 1903; S. Weidman - 1956 and others. Point by which to judge the function of the same system of the human body, mentally unite in the line "meridians".

On the electrical characteristics of the meridians can be concluded about the state related to these meridians, organs and systems. Each Meridian has many representative points (acupuncture points), the conductivity of which can completely characterize the state of the Meridian. Most convenient for the measurement points are located in the area lucazade�Togo joint and in the area of the foot. In interpreting the results of measurements are considered not so much the absolute value, how much is the ratio of these quantities. The technique is constructed in such a way that examines not only the functions of individual organs, but also the totality of the functioning of the organs interconnected, i.e. describes a situation where all the organs affect each other. In this scenario, you receive the opportunity to provide a functional diagnosis. The method allows to detect the disease, when clinical techniques, they are not detected. Diagnosis using the measurement of electrical parameters of the skin (elektrotermometria), is currently considered one of the proven methods of functional diagnostics. The measurement electrode produced a study of representative acupuncture points on the right and left. Generally accepted is the concept of "physiological corridor (the corridor of acceptable values), as follows. For optimum functioning of the body is characterized not so much "good" the absolute values of physiological indices as their symmetry and minimum range of values. The permissible deviation from the mean, which is defined as "the physiological corridor", is +10%. The bodies falling from the corridor, require therapy. In subsequent methods elektrotermometria repeatedly powersense�was ovalis, created more sensitive are the perfect instruments for measuring electrical characteristics of the meridians.

Thus, in the patent RU 2289388, publ. 20.12.2006, disclosed is a method of acupuncture diagnosis and correction of functional state of organism, which comprises measuring the conductivity of the skin in 24 biologically active representative points (BART) 12 paired meridians acupuncture skin zones, preparation of normalized tables elektroprovodimosti, the creation of individual corridor. Evaluation of conductivity is carried out according to the direction of the output values at the border of individual corridor. The border of individual corridor is determined by the formula B=CP·HF+Δ1and H=CP·KN-Δ2where is the upper border of individual corridor, SR - average normalized conductivity of the meridians, KV=1,05...1,2 is the normalization constant of the upper border of individual corridor, Δ1=2...5-the value of the tolerance compensating measurement errors to determine the upper border of individual corridor, N - lower border of individual corridor, KN=0,95 0,8...is the normalization constant of the lower border of individual corridor, Δ2=2...5-the value of the tolerance compensating measurement errors to determine the lower border of individual corridor. Identify the paired meridians in the cat�which one BART has conductivity, coinciding with the individual corridor, and the other has a conductivity greater than the upper or below the lower border of individual corridor. The diagnostic method improves the accuracy by determining the boundaries of each individual corridor.

In the patent RU 2137457 describes a method for determining the condition of the body, according to which measure the conductivity of 24 points in the twelve symmetric meridians. Applied measured value on the scale graph of the table. Pre-scale is applied on the right and left sides of each box of the table. Connect values among themselves by getting a "diagnostic line. In "physiological corridor marked the center line. The condition of the meridians is determined by the location of the diagnostic lines" on the borders of the physiological corridor" and its Central line. With its location within the boundaries of the "physiological corridor and parallel to the center line of the state of the Meridian and appropriate authorities define as normal. With its location along the borders of the physiological corridor, or reject them and the location parallel to the center line and at a non-parallel arrangement within the "physiological corridor or beyond its borders, the state of the Meridian and appropriate authorities define as pathological. Ability� allows rapid diagnosis of the body.

However, all current methods, being simple and not time-consuming, do not take into account individual parameters of patients, and the boundaries of the corridor rules are permanent, not taking into account the sensitivity with which you can conduct diagnostics.

The closest to the present invention is a method of Express-diagnostics according to the patent RU 2008887, which is also based on the conductivity measurements of the parameters of the skin in the area of acupuncture points. When implementing the known method define the primary and secondary zones of possible deviations from the arithmetic mean value of all measurements, are compared, and the measured values with the limits of zones by summing the measured values with certain points, define additional diagnostic criteria, against which, as well as taking into account the measured values with respect to the limits of the judge of possible pathological changes in the patient's body.

This method, as well as all of the above, does not take into account the sensitivity with which you can conduct diagnostics, and does not take into account individual parameters of each patient to establish the width of the corridor limits.

The problem to be solved by the present invention, consists in carrying out Diagne�sticks with a given sensitivity and tailored for each patient corridor limits.

The proposed method of monitoring the functional status of the patient includes:

the conductivity measurement of 24 points represented 12 symmetrical meridians, the definition of mean value of these measurements with the establishment of the corridor of acceptable values for a given patient, the results of comparison with which the obtained values of the indicators are judged on the functional status of the patient, using the indicators: the ratio of the sum of the values of electrical conductivity points of Yin meridians to the sum of the values of electrical conductivity points aniska meridians, the ratio of the sum of the values of electrical conductivity points on the feet, the ratio of the sum of the conductivity values of the points measured on the left side of the body, to the sum of the conductivity values of the points measured on the right side of the body,

the conductivity measurement of the patient is carried out at voltages of 5 V, and/or 9 and/or 12 V, and when using patient data obtained by measurements in a voltage of 9 V, recalculate the measured values of electrical conductivity mentioned representative points according to the formula:

I new=9/(29/(I MEAs-0,1)*Coeff,(I)

when using patient data obtained by measurements in �apryajennyi 12, recalculate the measured values of electrical conductivity mentioned representative points according to the formula:

I new=12/(29/(I MEAs-0,1)*Coeff,(II)

when using data obtained by measurements in a voltage of 5 V:

I new=I MEAs*Coeff,(III)

where in (I), (II) and (III) respectively:

I new - converted value of the electrical conductivity,

I MEAs is the measured value of conductivity,

Coeff - the value of the correction coefficient taking into account the heterogeneity of conduction through the meridians, in accordance with table 1 below

next, the recalculated values are transferred to the values given by the formula:

I t=I new/I th,

where:

I t is given the value of electrical conductivity,

I new is recalculated without bringing the value of electrical conductivity,

I CP is the arithmetic average of all measurements made on 24,

next, define the boundaries of individual corridor standards for a given patient depending on the target sensitivity of CV diagnostics and width of the corridor of acceptable values SDP conductivity, SDP represents the dispersion of values e�astroproject, measured in a given patient, and the sensitivity of CV diagnostics is chosen depending on the available sample of patients with this disease, and the values of the boundaries of individual corridor standards for a given patient is determined as follows:

- first calculate the intermediate coefficients KN for the lower KV and upper boundaries of the corridor, respectively:

KN=1-(1-PI)*SDP/2,1;

KV=1+(1-KN)*1,1;

- and expect actually lower and In the upper border of individual corridor rules:

N=K*(I th,;

In=KV*I Wed;

- I carried out a comparison of the t obtained with the boundaries of individual corridor limits.

The technical result is reinforced by the fact that as parameters for assessment of the functional state take 24 shows the values of the electrical conductivity, the simple average of all 24 recalculated values of electrical conductivity, the ratio of the sum of the values Yin meridians to the amount aniska meridians, the ratio of the sum of the values of the electrical conductivity of the hands to the sum of the values of the electrical conductivity of the feet, the ratio of the sum of the values of electrical conductivity measured on the left side of the body, the ratio of the sum of the values of electrical conductivity measured on the right side of the body. When making a conclusion about standing meridians use data on age and sex of the patient. To improve the accuracy of diagnosis�and take into account the body temperature of the patient, systolic and diastolic blood pressure, weight and parameters of clinical blood analysis. Determine the specificity of diagnosis, representing the proportion detected Express-diagnostics of patients with disease that is not revealed by the methods of classical medicine.

The method is based on the fact that there is a correlation between the DC conductivity at specific points on the hands and feet of man and his functional status. Conductivity in the method is measured with a special device, the so - called sensor having a safe open circuit voltage (open electrodes) 5, and the short-circuit current (when the closed electrodes) 37 μa. For conductivity measurement may be used in the device disclosed in the patent for invention RU 2142251 or the patent for useful model RU 79405. To measure is used by 6 points on each hand and foot (Fig. 1). The adopted order of points is as follows:

1) 6 points on the right hand (point H1-h6),

2) 6 points on the right foot (F1-F6)

3) 6 points on the left hand (point H1-h6),

4) 6 points on the left leg (F1-F6).

Table 1 shows the numbers of the meridians, their adopted names, the Eastern belonging to Yin/Yang and the point at which perform the measurement.

Since the values of measure�Xia on these meridians and the right and left, the total number of measured values is equal to 24. Later named Meridian measured parameters and a set of parameters obtained by calculation. The order of dimensions does not match the serial numbers of the meridians. In this regard, the measurement results are assigned to the respective rooms of the meridians.

Obtained by using sensor values of conductivity are calculated in unit conversion from measured values of N measured in the new values N new. This is done in order to account for the transition measurements on voltages of 12 and 9 used on a safe voltage of 5 V. the Conversion is carried out according to the formula:

N new=9(12)/(29/MEAs-0,1)*Coeff;

where N is a newly - converted value of the electrical conductivity,

MEAs. is the measured sensor value of conductivity,

Coeff - the value of the corresponding coefficient from table 1.

in the case of data accumulated during the measurement at a voltage of 5 V, the conductivity value only danosaur to Coeff table. 1. Recalculation is necessary in order to take into account the heterogeneity of conduction through the meridians and to use the data accumulated on the previously used voltage. In the future, with the accumulation of new static data from the recalculation will be dropped.

Based on the recalculated values of N define a new base on�the EO parameters which later will be used in assessing the patient's functional status. Estimation of the parameters described in the nearest analogue EN 2008887. These parameters are as follows:

1. Icp - the arithmetic average of all 24 values recalculated measurements

2. Yin - the sum of the Yin meridians

3. Jan - the sum of the Yang meridians

4. top - the sum of the meridians of hand

5. bottom - the sum of the meridians of foot

6. right - the sum of the right-wing meridians for hands and feet

7. left - the sum of the values of the left meridians for hands and feet

8. the ratio of Yin/Yang

9. the ratio of top/bottom

10. the ratio of left/right

Choose the recalculated values are again converted in the to compensate for the methodological error of measurement associated with changes in the humidity of the skin in different climatic environments. The conversion is performed by dividing the values I new the value of I Ms.

The recalculated values of the parameters count is given by the formula:

I t=I' new/Icp,

where I t is the value of the electrical conductivity,

I' new - recalculated without bringing the value of electrical conductivity,

Icp - the arithmetic average of all measurements made on 24.

24 shows a set of values and parameters of Yin/Yang, up/down, left/right, sex, age, PR Icp�astavliaut a basic set of parameters which detect the presence of a disease. Determination of the presence or absence of diseases is carried out using the parameters specified in EN 2008887, or options specified above.

In some diagnostic algorithms in addition to these basic parameters to improve the accuracy of diagnosis can be considered the human body temperature, systolic and diastolic blood pressure, weight, values of parameters of clinical blood analysis.

The width of the corridor of acceptable values of electrical conductivity SDP determined using the data obtained as a result of repeated studies of the patient. SDP is an individual patient. For example, some patient in the process of multiple surveys, the variation of the electrical conductivity ranged from 0,1*to 3.1 Icp*Icp. Therefore, this patient is allowable width of the corridor SDP will constitute 3.1-0,1=3,0.

Next, define the individual corridor norms for each patient depending on the target sensitivity of CV diagnostics and width of the corridor of acceptable values of electrical conductivity.

Under the diagnostic sensitivity understand the proportion of patients identified with this diagnosis, of the total number of patients with this disease. For example, the diagnostics revealed 8 patients disease data�amount of force. It is known that in this sample there are 10 disease patients data. Therefore, the sensitivity of diagnosis is CV=8/10 or 80%.

For example, set the required sensitivity of diagnosis is 75%, and calculate the border of individual corridor standards. To do this, calculate the intermediate coefficients for the lower and upper bounds, respectively:

KN=1-(1-PI)*Sm/2,1=1-(1-0,75)*4,0/2,1=0,524

KV=1+(1-KN)*1,1=1+0,476*1,1=1,524

Next, calculate the actual border when the magnitude of the correction cut Δn=0

N1=KN*Icp=0,524*Icp

B1=KV*Icp=1,524*Icp

Thus, the presented methodology can be analytically based on the sensitivity of the Ft, and the permissible range of values of elektrotermometria - corridor width of SHD in relative units (normalized to the average value of elektrotermometria, calculate the boundaries of the norm for each individual patient. In the absence of retrospective data about a specific patient width of the corridor of acceptable values with accuracy of 98% can be taken, equal to 4.5.

In the basis for calculating expected the following.

If norm corridor zero width (i.e., H1=B1), the results of all examinations of patients will be outside the normal range, i.e., all patients will be identified as sick and CV=1.

If N1=0 and B1=∞, then all the results of the surveys will be náchod�tsya within the corridor standards for each of the nmeridians, because all will be identified as healthy and CV=0.

The corridor of standards is asymmetrical relative to the mean value, if the width of the corridor to the norm of H1 to CP I to be 1, the width of the corridor to the rules from CP to Q1 equal to 1.1 (the total width of the corridor is the norm in this case is equal to 2.1 relative units).

The real middle of the values for the various meridians differs by almost 60%.

To get the real means for each of thenmeridians to the value of I CP is added to the correction interval Δn, it is important to understand that a segment of Δn can be both positive and negative.

At the initial stage, until the accumulated statistical data, assume that Δn=0. In the future, the value of Δn is specified as the accumulation of evidence-based clinical material.

Further determine the specificity of diagnosis. Under diagnostic specificity understand the Special share revealed the diagnosis of patients in whom the disease is not identified by classical methods, of the total number of such patients.

For example, the diagnostics revealed that 65 patients the disease is absent. It is known that in this sample there are 100 patients in whom classical methods is not established the presence of this disease. Therefore

Special=65/100 or 65%.

Specificity Oprah�elaut based on static data on the diagnosis and Nakatani empirical formula:

Special=(1-Ft2)1/6

In recent years on the basis of statistical data formulated a set of diagnostic algorithms for various diseases. In these algorithms, the simultaneous release of a number of meridians outside the corridors of the norm (in Hypo - or hyperfunction) is a clear sign of the presence of a disease.

Using the described method for the determination of individual corridor standards Sogno to determine analytically the exact boundaries of the segments are getting these values in Hypo - or hyperfunction of:

Cut hypofunction from 0 to H1

Cut hyperfunction from B1 to 4.5

Example 1.

In the example shown the total sample consisting of 75 patients with psoriasis, and 9984 people who have psoriasis are not identified. Just 10059 patients. For all patients with psoriasis Sm=2,1, therefore, KN=CV, KV=1+(1-PI)*1,1.

For different diagnostic sensitivities obtained the following design values are presented in table 2.

in which each pair of Sensitivity and Specificity corresponding to the upper (B1) and lower (HI) the boundaries of the corridors of the norm. These boundaries are calculated based on the expressions given in the description of the invention, namely:

KN=1-(1-PI)*Schd/2,1=1-(1- 0,75)*4,0/2,1=0,524

KV=1+(1-KN)*1,1=1+0,476*1,1=1,524

N1=KN*Icp=0,524*Icp

B1=KV*Icp=1,524*Icp

where Icp=1 in these units, i.e. in the values divided by Icp)

Therefore, the doctor is not necessary to consider the boundaries of HI and B1, it is enough to set the sensitivity of the Ft, and he immediately based on the table. 2 get the desired boundary of the corridor limits.

Sensitivity (CV) is specified by the physician. Depending on facing physician tasks, whether the initial examination, clinical examination or re-examination of the same patient, the doctor sets the sensitivity index, which is based on his experience, knowledge and specific situation will allow us to best assess the condition of the patient. For example, on initial inspection sensitivity is set at the level of 70-75%, to not have to deal with the excess number of lejebolig. Repeated examinations increase the sensitivity to the level of 85-90%, to more clearly track and initial analysis, and process patient observation. When examining children choose the maximal sensitivity to 95%.

On a real sample for variation of the boundary H1 indicator top/bottom in the range from 0,96 0,69 obtained the following data, which are summarized in table 3. Evidence suggests that the discrepancy between the calculated and real values does not exceed 5%.

Example 2. We examined the patient P, the data are summarized in table 4.

Used� the collected data and presents the methodology it can be concluded that the investigated patient, for which data are summarized in table 4, with a sensitivity of 96% and specificity of at least 66% of the psoriasis patients, since the average up/down=0,9.

The proposed method has the following advantages over existing today:

- provides the ability to calculate analytically the desired boundaries of the norm (H1 and B1) based on the sensitivity of diagnosis,

- these borders are doing, individually for each patient, for this accumulate the necessary statistics on the measurements. This statistic allows you to define individual value SDP for a given patient. Prior to the accumulation of static data for all patients to use the average value Sm, equal to 4.5.

Method of monitoring the functional status of the patient, including:
- measurement of electrical conductivity of 24 points represented 12 symmetrical meridians, the definition of mean value of these measurements with the establishment of the corridor of acceptable values for a given patient, the results of comparison with which the obtained values of the indicators are judged on the functional status of the patient, using the indicators: the ratio of the sum of the values of electrical conductivity Yin points �of eridanos to the sum of the values of electrical conductivity points aniska meridians, the ratio of the sum of the values of electrical conductivity points on the hands to the sum of the values of electrical conductivity points on the feet, the ratio of the sum of the conductivity values of the points measured on the left side of the body, to the sum of the conductivity values of the points measured on the right side of the body,
characterized in that
- measurement of electrical conductivity of the patient is carried out at voltages of 5V, and/or 9B, and/or 12V,
and when using patient data obtained when measuring the voltage of 9V, recalculate the measured values of electrical conductivity mentioned representative points according to the formula:

I new=9/(29/(I MEAs-0,1)*Coeff,(I)

when using patient data obtained by measurements in the voltage of 12V, recalculate the measured values of electrical conductivity mentioned representative points according to the formula:
I new=12/(29/(I MEAs-0,1)*Coeff,(II)

when using data obtained when measuring the voltage of 5V:
I new=1 MEAs*Coeff,(III)

where in (I), (II) and (III) respectively:
I new - converted W�Uchenie conductivity,
I MEAs is the measured value of conductivity,
Coeff - the value of the correction coefficient taking into account the heterogeneity of conduction through the meridians, in accordance with table 1, presented in the description,
next, the recalculated values are transferred to the values given by the formula:
I t=I new/I Wed,
where:
I t is given the value of electrical conductivity,
I new is recalculated without bringing the value of electrical conductivity,
I CP is the arithmetic average of all measurements made on 24,
next, define the boundaries of individual corridor standards for a given patient depending on the target sensitivity of CV diagnostics and width of the corridor of acceptable values SDP conductivity, SDP represents the dispersion of values of electrical conductivity measured in a given patient, and the sensitivity of CV diagnostics is chosen depending on the available sample of patients with the disease,
and the values of the boundaries of individual corridor standards for a given patient is determined as follows:
- first calculate the intermediate coefficients KN for the lower KV and upper boundaries of the corridor, respectively:
KN=1-(1-PI)*SDP/2,1,
KV=1+(1-KN)*1,1;
- and expect actually lower and In the upper border of individual corridor rules:
N=K*(I th,
In=KV*I Wed;
- I carried out a comparison of t with �must register the boundaries of individual corridor standards.



 

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SUBSTANCE: group of inventions refers to medicine, namely to paediatrics, and can be used to control an amount of breast milk consumed by a nursing infant. The method involves measuring a breast electric resistance and a breast electric capacity before and after breastfeeding. The derived values are multiplied to obtain the characteristics variation information during the breastfeeding. The change information are related to the amount of milk consumed by the infant. What is presented is a breastfeeding control system, which comprises an electric capacity measuring unit designed for measuring the electric capacity variations before and after breastfeeding. Besides, the system comprises a breast electric resistance measuring unit. Also, the system comprises a processing unit configured to calculate the product of the electric capacity and the electric resistance, and to match the derived product with the amount of milk consumed by the nursing infant.

EFFECT: inventions enables controlling the amount of breast milk consumed by the infant and assessing the adequacy of breastfeeding.

16 cl, 20 dwg, 3 ex

FIELD: medicine.

SUBSTANCE: method involves preliminary assessment of the reversible abnormal changes of enamel accompanying early cariosity. That is ensured by diagnostic tests of solid dental tissues conducted by using light-induced fluorescence and electrometric measurement techniques followed by therapy involving daily applications of the Radogel-GABA preparation. If observing visually detected changes with a current intensity of 0.21-1.99 mcA in the lesion and the presence of fluorescence, the preclinical changes of enamel are diagnosed requiring 5 therapeutic procedures with the above preparation. Visualised tarnishing of enamel accompanied by a current intensity of 2.00-3.99 mcA in the lesion and the presence of fluorescence, an early carious change of enamel at the stage of a dead spot is diagnosed, and 7 therapeutic procedures are conducted. If visualising a white spot of enamel accompanied by a current intensity of 4.00-5.99 mcA in the lesion and the presence of fluorescence, an early carious change of enamel at the stage of a white spot is diagnosed, and 10 therapeutic procedures are conducted. If visualising a white spot of enamel accompanied by a current intensity of 6.00-7.99 mcA in the lesion and the presence of fluorescence, an early carious change of enamel at the stage of an intense white spot is diagnosed, and 15 therapeutic procedures with the Radogel-GABA preparation are required.

EFFECT: method provides the high-effective therapeutic exposure on caries by the timely recovery of the protein dental matrix with simplicity and ease of use at massive dental visits.

2 tbl

FIELD: electricity.

SUBSTANCE: invention is related to systems of magnetic impedance tomography. The system comprises an excitation system having several exciting coils to generate a magnetic excitation field intended to induce eddy currents in a surveyed volume, a measurement system with several measuring coils to measure the fields generated by the induced eddy currents, at that the measuring coils are placed in a volumetric (3D) geometrical assembly and a reconstruction device intended for the receipt of measurement data from the measurement system and for the reconstruction of the object imaging in the surveyed volume against the measured data. Each measuring coil covers an area and is oriented in essence transversely to the magnetic field power lines in the exciting coils, separate measuring coils cover jointly the area corresponding to the volumetric (3D) geometrical assembly, at that the exciting coils cover the area where the measuring coils are placed. The area covered by each of the separate measuring coils is oriented perpendicular to the area covered by the exciting coils.

EFFECT: usage of the invention allows improving the quality of imaging for volumetric objects.

8 cl, 2 dwg

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine. A device comprises: a measuring device, a calculation device and an input device. Implementing the method involves extracting the living body information measured by the measuring device. The input device is used to accept the biological component information measured by the other device together with the date and time information. That is followed by determining if the biological component information is actual. If the biological component information is stated to be actual, the calculation device is used to calculate the biological information by formula: f(ρ)=a2·1/ρ+b2·W+c2·S+d2·L+e2. If the biological component information is stated to be inactive, the calculation procedure follows formula: f(ρ)=a1·1/ρ+b1·W+c1. Herewith, a1-c1, a2-e2 are the pre-set constants, ρ is a living body's specific resistance, S is a body part cross-section, L is a body part length, W is a living body weight.

EFFECT: group of inventions enables providing the more accurate body composition measurement by using the data extracted by the other devices.

8 cl, 14 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to occupational medicine, and can be used for specifying the indications for the instant correction of the psychophysiological states. A cardiointervalogram is recorded before and after professional activity. A range of RR interval lengths (MxDMnbefore, MxDMnafter), a square root of a total difference of a sequence of RR intervals (RMSSDbefore, RMSSDafter) and a mode amplitude of RR interval lengths (AMobefore, AMoafter) are determined. Differentiation functions G1 and G2 are calculated. If G1 is less than G2, the individuals being tested are considered to be in need of the instant correction of their psychophysiological states. Otherwise, it is stated that the individuals being tested are not in need of the instant correction of their psychophysiological states.

EFFECT: examining the individual before and after the occupational activity, using the cardiointervalography findings and specifying the most significant criteria for the psychophysiological states assessment make the method increase the responsiveness to the process of detection if there are any individual-specific indications for the instant correction of the psychophysiological states.

2 ex

FIELD: medicine.

SUBSTANCE: stress test is administered by performing a physical load accompanied by recording cardiac parameters followed by performing a training load. The training load is preceded by administering a repeated stress test 30-60 minutes following the first one. The cardiac parameter consists in recording ST segment displacement and calculating ST index. The ST indices subsequent to the results of the first and second stress tests are compared. If the second index tends to decrease as compared to the first one by at least 10%, the training load is performed. A third stress test is administered 30-60 minutes later to evaluate a third ST index. The training load is performed for 24-48 hours on completion of the second stress test. The training load represents alternative clamping and blood flow recovery in the peripheral vessels. One cycle is expected to consist of at least 4 cycles of clamping and recovery procedures in the peripheral blood vessels. Besides, each clamping and recovery within the training load cycle alternates for 3-5 minutes.

EFFECT: method enables reducing the rehabilitation time of the IHD patients and reducing a risk of complications by providing a sparing load pattern.

2 cl

FIELD: medicine.

SUBSTANCE: invention represents a method for determining a probability of preserving the myocardium following infarction by creating an admission examination-based data array of 7 peripheral blood parameters, 11 biochemical analysis parameters and 6 parameters of standard 12-lead electrocardiogram in 200 patients with the Q-myocardial infarction and 200 patients without the myocardial infarction. The parameters are stratified with respect to 7 intervals, wherein values related to the probability of preserving the myocardium following infarction are derived by calculating a ratio of the patients without myocardial infarction to all the patients with acute coronary syndrome. The probability is evaluated in a specific patient by analysing the above parameters, searching the respective intervals and values related to the probability of preserving the myocardium in the data array. Summing up the derived values enables calculating an integrated index, which is normalised, and a dimension from 0 to 100% is reduced.

EFFECT: invention enables increasing the prediction accuracy of preserving the myocardium in the patients with acute coronary syndrome.

1 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: invention refers to medical equipment, namely to devices for measuring bioelectric potentials of the heart. An electrocardiograph comprises a supply unit, electrodes, a microcontroller, a computer, an analogue-to-digital converter, and a digital-to-analogue converter. The electrocardiograph has a multi-channel structure and comprises several identical channels. The electrodes are medical nanoelectrodes for the chest EEG recording. Outputs of the nanoelectrodes are connected to inputs of measuring amplifiers; outputs of the measuring amplifiers are connected to the first inputs of operational amplifiers outputs of which are connected to inputs of the analogue-to-digital converter; outputs of the analogue-to-digital converter are connected to inputs of microcontrollers, outputs of which are connected to the computer and to the second inputs of the operational amplifiers through the digital-to-analogue converter.

EFFECT: invention aims at the higher resolution of electrocardiographic equipment for non-invasive real-time micropotential recording on the electrocardiogram without applying any analogue and program filters, collecting cardiac pulses which lead to the distortion of true bioelectric activity of the heart for the purpose of early diagnostic of the heart diseases and eliminating the episodes of sudden cardiac death.

20 dwg

FIELD: medicine.

SUBSTANCE: EEG signal is recorded and digitised in symmetrical zones of the right and left cerebral hemispheres by monopole and dipole methods. After digitising, mean EEG signal values are calculated. A positive (+) active electrode position, wherein the EEG signal is supposed to be more electrically negative shows the hemisphere with the greater activity.

EFFECT: method enables simplifying and detecting the more active cerebral hemisphere more reliably.

2 ex

FIELD: medicine.

SUBSTANCE: continuous monitoring and ECG recording are performed. The ECG findings are used to specify a delay in shape of R wave and a length of an antrioventricular interval. The final result of atrioventricular delay is a symmetrical crowned P wave.

EFFECT: method provides increasing the effectiveness of cardiac resynchronising therapy by reducing complications and improving the patient's quality of life.

1 tbl, 1 ex, 1 dwg

FIELD: medicine.

SUBSTANCE: 12-lead electrocardiogram (ECG) is recorded. That is followed by measuring the ECG parameters: R wave amplitude in the aVL lead, S and R waves amplitudes in the V4 lead, Q wave and ST segment amplitudes and R wave length in the V5 lead, patient's Quetelet index; f(z) is calculated by the presented formula derived by mathematical statistics methods. If f(z) is 0.35 or more, the presence of at least one heart disease specified in left ventricular dilatation, lower ejection fraction, disturbed regional contractility, left ventricular aneurism, ventricular septum thickening, thickening of a left ventricular posterior wall.

EFFECT: method enables increasing the early detection of heart diseases at mass health examinations by observing specific ECG parameters.

2 ex

FIELD: medicine.

SUBSTANCE: registration of biomechanical characteristics of the ankle joint work is performed by means of a hardware-software complex in the process of a step cycle with the application of a motion capture system, a dynamic stabiloplatform and electromyography (EMG). First, light-reflecting markers are fixed on the patient's body, devices of wireless EMG are fixed on anterior and posterior groups of the shin muscles. An individual three-dimensional static skeleton model of the patient, for which characteristics of the step cycle are determined by the patient walking on the stabilometric platform with the number of not fewer than 5 repetitions, is created by means of the motion capture system. The obtained biomechanical characteristics are used to calculate the power of the ankle joint work, the pronation angle and the supination angle by means of the complex software. Comparative analysis of the said parameters with the parameters of the norm, varying in the following ranges: power of work 3.01÷4.56 W/kg, pronation angle 3.89÷4.78 degrees, supination angle 2.98÷3.67 degrees, is carried out. Pes valgus deformation of feet is diagnosed if the power of the ankle joint work and the supination angle reduce, and the pronation angle increases in comparison with the norm.

EFFECT: method provides the complex accurate quantitative early diagnostics of pes valgus deformation of the foot in children in short terms, taking into account the biomechanics of walking.

2 ex

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine. A method of non-invasive intracardial electrocardiography is realised by means of a device for non-invasive intracardial electrocardiography by the application of an interference device, possessing magnetic permeability and electric conductivity. ECG signals are registered by means of ECG. A magnetic field of selection is generated by means of selection with such a space diagram of the magnetic field intensity that the first auxiliary zone, possessing low magnetic field intensity, and the second auxiliary zone, possessing higher magnetic field intensity, is formed in the field of vision. Means of selection contains a unit of a selection field signal generator and an element of the selection field excitation, in particular magnets or coils of the selection field excitation. Space position of two auxiliary zones in the vision field is changed by means of excitation by the excitation magnetic field for the magnetisation of an interference device in the vision field to be changed locally. The excitation device contains a unit of the excitation field signal generator and an excitation coil of the excitation field. Detection signals are received by reception means. The detection signals depend on the magnetisation of the interference device in the field of vision, with the magnetisation being influenced by the change of the space position of the first and second auxiliary zones. Reception means contains a unit of signal reception and a reception coil for obtaining detection signals. Control over generation of respective magnetic fields is performed by control means for the movement of the interference device through the vascular system and heart in the direction, specified by commands of displacement and/or holding of the interference device in the constant position. Control means is intended for controlling the units of the signal generator for the generation and supply of controlling currents to respective excitation coils. Processing means are used to process the detection signals, which are received, when respective magnetic fields are applied, to determine the position of the interference device within the vascular system and heart by the processed detection signals. Evaluation means is used to evaluate the influence of the interference device on registered ECG signals.

EFFECT: application of inventions will make it possible to increase the accuracy of non-invasive intracardial electrocardiography.

10 cl, 8 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to cardiology and gynaecology, and can be used in the differential diagnostics of cardiogenic myocardial ischemia and the genital-cardial inhibitory reflex accompanied by pain syndrome caused by a gynaecological pathology. That is ensured by ECG recording. That is followed by two-side block of round ligaments of the uterus by an anaesthetic solution in an amount of 15.0-20.0 ml from each side. The ECG is recorded again 60-90 min after the block, and the recording is compared to the pre-block ECG. If the ECG findings tend to be positive, ischemia caused by the genital-cardial inhibitory reflex accompanied by pain syndrome caused by a gynaecological pathology is diagnosed. If no positive dynamic is observed, cardiogenic myocardial ischemia is diagnosed.

EFFECT: technique provides the effective differential diagnosis of cardiogenic myocardial ischemia and the genital-cardial inhibitory reflex accompanied by pain syndrome caused by a gynaecological pathology.

1 ex

FIELD: medicine.

SUBSTANCE: senior guinea pigs are exposed to optical light generated by light emitting diodes or fluorescent tubes at a colour temperature of 4,500 K within the wavelength region of 360-460 nm for various time distances. The exposure is assessed by functional activity indices of neutrophilic granulocytes and a mononuclear cell count.

EFFECT: using the method requires no expensive equipment, critical chemicals; it is of a particular importance for evaluating the biological safety of new artificial light sources embedded into a light-colour medium; it provides expanded information on biological effects of optical light.

3 tbl

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