Method for cluster differentiation of psychophysiological states

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to occupational medicine, and can be used for specifying the indications for the instant correction of the psychophysiological states. A cardiointervalogram is recorded before and after professional activity. A range of RR interval lengths (MxDMnbefore, MxDMnafter), a square root of a total difference of a sequence of RR intervals (RMSSDbefore, RMSSDafter) and a mode amplitude of RR interval lengths (AMobefore, AMoafter) are determined. Differentiation functions G1 and G2 are calculated. If G1 is less than G2, the individuals being tested are considered to be in need of the instant correction of their psychophysiological states. Otherwise, it is stated that the individuals being tested are not in need of the instant correction of their psychophysiological states.

EFFECT: examining the individual before and after the occupational activity, using the cardiointervalography findings and specifying the most significant criteria for the psychophysiological states assessment make the method increase the responsiveness to the process of detection if there are any individual-specific indications for the instant correction of the psychophysiological states.

2 ex

 

The invention relates to medicine, in particular to occupational medicine, and can be used for rapid determination of need for rapid correction of psychophysiological state of a person after professional activities.

The prior art discloses a method for determining the adaptability of a person to diving training (patent RU 2444985, publ. 20.03.2012) by assessing the functional state of the body before, during and after the dive in diving equipment regenerative type under water in the pool to a depth of 3 m and its stay on the ground for 10 min, and psychophysiological indicators assess the status before the dive, and the state of the cardiovascular and nervous systems was assessed after immersion, and then according to the formula

APD=0,12 P+0,15 S-A 0,025+0,06 D+0.002 M+0,014 C-0,22 K+0,31 T-31,7,

where R is the heart rate after immersion under water in the pool, beats/min;

S - systolic blood pressure after diving under water in the pool, mmHg. article;

A - the speed of information processing after immersion under water in the pool for correction of the test with Landolt rings, bps;

D - diastolic blood pressure after diving under water in the pool, mmHg. CT;

M - minute volume of blood circulation after immersion under water in the pool, ml;

With - latent period slozhnoustroenny reaction with the choice after immersion under water in the pool MS;

It is the critical fusion frequency of light flickers after immersion under water in the pool, Hz;

T - jet anxiety before diving under the water in the pool, points;

determine the adaptive capacity of a diver (APD) when conducting diving training in points; divers (cadets - future divers), APD scored not less than 7.3 points and no more than 16.8 points, referred to the group with a satisfactory adaptation to diving training, 16,81-20.1 points to the group with the tight adaptation, and cadets - future divers score of less than 7.3 points and more of 20.1 points, - to the group with unsatisfactory adaptation to diving training. The disadvantage of this technical solution is the fact that the indicators of psycho-physiological status assessed only before the dive, and the state of the cardiovascular and nervous systems assessed only after the dive that does not reflect the change in physiological conditions due to the performance of professional activities.

The closest analogue, is known in the art, is a Method of monitoring the state of human health is the way Amiranoff (application for invention RU №2006107041/14, publ. 10.08.2006) - using a computer on the basis of indicators of heart rate variability and blood pressure (HRV):

the average duration of R-R intervals (RRNN) in the recording, MS;

the most common duration - fashion - of R-R intervals (M0in the recording, MS;

the modal share of R-R intervals (S0records, %;

the variation in R-R intervals in the record relative to the mean value - standard deviation (SDNN), MS;

the difference between the maximum and minimum values in a record - variational sweep - R-R interval (MxDMn), MS;

the index of tension of regulatory systems of the body (JN), CONV. ed;

the total power spectrum of fluctuations in the duration of R-R intervals in the range up to 0.4 Hz (TP), MC2;

the absolute power of high frequency oscillations in the duration of R-R intervals in the range of 0.15-0.4 Hz (HF), MS2;

the absolute power of low frequency oscillations in the duration of R-R intervals in the range of 0.04-0.15 Hz (LF), MS2;

the absolute power of high frequency oscillations in the duration of R-R intervals in the range of 0.15-0.4 Hz (LF), MS2;

absolute power in excess of low-frequency oscillations in the duration of R-R intervals in the range of 0,015-0,04 Hz (VLF), MS2;

the relative power of high frequency oscillations in the duration of R-R intervals in the range of 0.15-0.4 Hz (HFnu), %;

the relative power of high frequency oscillations in the duration of R-R intervals in the range of 0.15-0.4 Hz (LFnu), %;

for the relative�capacity high-frequency oscillations in the duration of R-R intervals in the range of 0.15-0.4 Hz (VLFnu), cent;

the ratio of the mean values of the absolute power of low-frequency and high-frequency components of the spectrum of HRV (LF/HF), CONV.ed;

average heart rate on record (PE), beats/min;

average diastolic blood pressure (ADD), mm Hg.St.;

average systolic blood pressure (ADF), mm Hg.CT., which is determined using a hardware-software complex "varikard" BK1.4 to record a five-minute continuous recording of heart rate of the person collecting the data

b(Tij); j=1...N1; i=1...N* Ni≥1; N*>1,

where b(Tij- the result of measuring bi∈V* a person at rest at time Tij:

Tn≤Tij≤T≤TW; j=1...Ni

Tn- the start time of tracking the health of a person;

T - time to determine the degree of health of the person;

TW- completion time monitoring the state of health of the person;

Ni- number of measurements of bi∈V* the person for the time Tnto T;

In* - the set of indices of HRV, examined the person during the time from Tnto T;

N* - volume V*,

compute the set of values

Mj1, Sj1Nj1, j=1...N*

and compare it with the set of values

Mj0, Sj0Nj0, j=1...N*,

where Mj1and Sj1- average ar�fetichisme and the standard deviation of the sample of the survey results the j-th indicator of HRV person;

Nj1is the sample size of the survey results of the j-th HRV of man, by which establish the Mj1and Sj1: Nj1≥1

N* is the number of indices of HRV, which at time T there is a specialist available the results of the survey HRV person;

Mj0and Sj0- arithmetic mean and standard deviation of the sample of the survey results the j-th indicator of HRV at rest in the control group of healthy people to which a person belongs, at least by gender and age, and installed with confidence probability P(1 > P≥0,95);

Nj0is the sample size of the survey results the j-th indicator of HRV in the control group of healthy people:

Nj0>1,

characterized in that at any time T, including T=Tnor rather, when

Ni*=1; i=1...N*

the degree of human health and, ultimately, the degree of transferability load his body, set with probability P, sequentially performing the following steps:

1) from the results of a survey of man's accumulated since the first survey, separates the part that at the time of the survey human T yet

is deprecated

2) find out whether the condition

N≥Nmin (1)

and if not, suspend the calculation and displays the message

"Additional data"(2)

but if the condition (1) is satisfied, then set the value

aj=aj(P, Mjk, SjkNjk; k=0,1; j=1...N); j=1...N

and

βj0j0(P, Mjk, SjkNjk; k=0,1; j=1...N); j=1...N,

where N is the number of indicators for which at time T are non-obsolete the results of examination of a person;

Nminis a specific specialist minimum value N;

ajis the limit value of the j-th indicator, valid for the human body at the time T:

aj=ajminat Mj1≤Mj0and aj=ajmaxat Mj1>Mj0;

ajmin- the minimum value of j-th indicator, valid for the human body in the time T;

ajmax- the maximum value of j-th indicator, valid for the human body at time T;

βj0binary number equal to 1, if the degree of the overall health status of the person at time T a set of data

(Mj1, Sj1, aj); j=j0; j0=1...N

must be taken into account, and 0 otherwise

3) new�tween, whether the condition is

N1=j=1Nβj0Nmin

and if not, suspend the calculation and displays the message (2), and if the condition (3) is satisfied, then set the value

Yj=YJ(P, Mjk, SjkNjk; k=0,1; j=1...N1)∈(0, 1]; j=1...N,

where Yj- the degree of human health, set the sum of the data

(Mj1, Sj0, aj); j=j0; j0=1...N,

4) determine the amount of

Y=Y(Yj; j=1...N1),

where Y is an indicator of General state of health at time T: Y=1 if the person at time T is healthy and 0<Y<1, if a person at time T is sick, 5) establish the value of G,

where G is the degree of transferability of the human body load, obtained them as a result of medical and/or other external and internal influences in the period from Tk-1up to Tk=T(k=1,2,3...):

G=1⇔Yd=Yp=1;

Yd- the Y value set to obtain the load of the human body;

Yp- the Y value that is set after receiving the load of the human body,

6) figure out per�tsya whether the condition

Gp<Gd,

where Gdand Gp- of a value of G that are installed by the results of the examination of a person before and after receiving the load, respectively, and, if so, make a conclusion about the intolerance of the human body given the impact of what informed specialist

7) set of data

G, P, Mjk, SjkNjkandj, γj, βj0; k=0,1; j=1...N,

save. The disadvantage of this solution is that it focuses on the use of individual and population-based normative (boundary) values of monitored indicators, which does not reflect the individual (personalized, personalized) change of psycho-physiological States due to the performance of professional activities.

The technical task of the present invention is the ability to detect the need for rapid correction of psychophysiological state of a person after professional activity (day, shift) to implement measures for the conservation of health personnel.

The solution of a technical problem is achieved in that before, during and after professional activity register kardiointervalogrammy and determine the variation of the magnitude of the duration of RR-intervals (MxDMnsub> to, MxDMnafter), the square root of the sum of differences of successive series of RR-intervals (RMSSDto, RMSSDafter), the amplitude of the fashion of the duration of RR-intervals (AMOtoAMOafter) and calculate the derivative of functions (G1 and G2)

G1=-0,005(MxDMnafter-MxDMnto)-0,031(RMSSDafter-RMSSDto)+0,01(AMOafter-AMOto)-0,768,

G2=0,032(MxDMnafter-MxDMnto)-0,115(RMSSDafter-RMSSDto)-0,031(AMOafter-AMOto)-3,372,

and if the value of G1 does not exceed the value of G2, we surveyed identify as requiring rapid correction of psychophysiological state, in other cases, the examinee is determined as not requiring rapid correction of psychophysiological state.

The technical result provided by the given set of features is to improve the efficiency of determining the presence/absence of individualized evidence for rapid correction of psycho-physiological States on the basis of his performance before and after the execution of professional activities.

Implementation of the claimed method is as follows.

1) Before the beginning of professional activity in subjects at rest sitting or lying down for at least 2 minutes to register kardiointervalogrammy. Processing cardionet�salagrama, by standard methods to determine the variation of the magnitude of the duration of RR-intervals (MxDMnto), the square root of the sum of differences of successive series of RR-intervals (RMSSDto), the amplitude of the fashion of the duration of RR-intervals (AMOto).

2) Upon completion of the professional activity in subjects at rest sitting or lying down for at least 2 minutes to register kardiointervalogrammy. The duration and method of registration (sitting or lying) cardiointervalogram are conducted before and after the professional activity must be the same. Processing kardiointervalogrammy determine the variation of the magnitude of the duration of RR-intervals (MxDMnafter), the square root of the sum of differences of successive series of RR-intervals (RMSSDafter), the amplitude of the fashion of the duration of RR-intervals (AMOafter).

3) based On the obtained values of indicators of psychophysiological state calculate the derivative of functions (G1 and G2)

G1=-0,005(MxDMnafter-MxDMnto)-0,031(RMSSDafter-RMSSDto)+0,01(AMOafter-AMOto)-0,768,

G2=0,032(MxDMnafter-MxDMnto)-0,115(RMSSDafter-RMSSDto)-0,031(AMOafter-AMOto)-3,372,

4) the subject for which the value of G1 does not exceed the value of G2 belong to the class of the needy in the Express cor�ecchi psycho-physiological States, other surveyed belong to the class not requiring rapid correction of psycho-physiological States.

5) requiring rapid correction of psycho-physiological States carry out a correction by one of the available methods available to the health worker: psychological relaxation, douches, baths, aromatherapy, etc. Constant neediness of a person in the Express correction

neurophysiological States is the basis for the in-depth medical examination in the interests of making decisions about compliance with health requirements of professional activity, the need for medical correction of health, the need for correction of mode of work and rest, etc.

Under physiological condition understand the integral characteristics of the body and personality of the person determining potential or realized possibilities to the specified requirements of reliability and efficiency of professional activity. Diagnostics of psychophysiological state involves getting it integrated assessment that combines objective and subjective characteristics.

For developing a method of cluster of differentiation psycho-physiological States used diagnostic system, SOS�Mr sage from several blocks:

1. The physiological unit tests:

a) study of the state of the system of Central and peripheral hemodynamics at rest: systolic, diastolic, mean arterial pressure, heart rate, stroke volume of blood circulation, cardiac output;

b) the study of autonomic regulation of cardiac activity at rest in the sitting position: the maximum and minimum duration of RR-intervals, their difference and ratio; the square root of the sum of differences of successive series of RR-intervals; the proportion of RR-intervals with a difference of more than 50 MS; standard deviation, coefficient of variation, variance, fashion, the amplitude of the fashion of the duration of RR-intervals; AMO - amplitude fashion with a width of class 50 MS, AMO.8 - amplitude of the fashion when the width of the class 1/128 s, SI - stress index, TP is the spectral power of RR-intervals;

b) conducting a functional exercise tests with determination of the delay time of the breath on the exhale (sample of Genc) and inspiratory (test the Boom), the measure of reactivity in the sample Rod and the sample of Genc.

2. Block psychophysiological tests:

a) determination of the time simple and complex sensorimotor reaction;

b) test of differential self-assessment of psychophysiological state technique SAN (health, activity, H - mood).

According to the results of di�omicheskogo complex psychophysiological staff surveys of industrial production before and after a four-hour shift or at the beginning and at the end of the eight-hour day depending on work schedule obtained the primary information. By processing this information, the selected two clusters of psycho-physiological States, interpreted according to the full list of indicators, and then the resulting complex of informative parameters of the minimum dimensions that allow to differentiate the current psychophysiological state after professional activity to one of two clusters. The examples of the method.

Example 1. Male, 25 years old, an employee of industrial production, professional activity is carried out eight-hour shifts. Before and after the eight-hour day at rest in the supine position for two minutes registered cardiointervalogramms. As a result of its processing, we obtained the following values of the indicators of psychophysiological state:

- prior to the beginning of professional activity:

MxDMnto=286 MS, RMSSDto=43,386 MS, AMOto=35,572%;

- on completion of professional activities:

MxDMnafter=413 MS, RMSSDafter=57,799 MS, AMOafter=24,533%.

Substituting the values of the indicators in differentiating functions, calculated values:

G1=-0,005(413-286)-0,031(17,88-43,386)+0,01(24,533-35,572)-0,768=-1,388693;

G2=0,032(413-286)-0,115(17,88-43,386)-0,031(24,533- 35,572)-3,372=-0,623286.

The condition G2 > G1, therefore, the person does not require rapid correction of psychophysiological state�deposits.

Speaking about the relationship of the method of diagnosis with a diagnostic factor in the claimed method on the relationship assessment cardiointervalogram are conducted with a physiological condition), it should be noted that (evaluation of the functional state of the organism in labor loadings on indicators of activity of regulatory systems: methodical recommendations / P. M. Baevsky [and others]. - Chelyabinsk, 1986. 20):

- analysis of cardiointervalogram are conducted widespread as a method to quantitatively characterize the activity of different divisions of the autonomic nervous system through their influence on the function of the sinus node of the heart, which manifests itself in oscillations of the duration of RR-intervals;

- variational sweep durations of cardio intervals (MxDMnafter) increases when airplane circuit, the attenuation of sympathetic regulation of rhythm, rate variability increases, increases the range of durations of cardio intervals reduced the number of the same type on the duration of the intervals; increase the variation range after the work shift in the experimental group shows a reduction in tone of the sympathetic nervous system and the change of regulatory mechanisms of cardiac activity in favor of decentralization;

- the square root of the sum of differences of successive series of RR-intervals (RMSSDpic�e ) is an indicator of parasympathetic activity of autonomic regulation;

- the amplitude of the fashion of the duration of RR-intervals (AMOafter) is an index of activity of regulatory systems, due to the adequate functionality of the body load.

Presented data confirm the suitability of the developed method to achieve the claimed technical result.

Example 2. Male, 29 years old, driver. Before and after the eight-hour day at rest in the sitting position for two minutes registered cardiointervalogramms. As a result of its processing, we obtained the following values of the indicators of psychophysiological state:

- prior to the beginning of professional activity:

MxDMnto=200 MS, RMSSDto=25,721 MS, AMOto=57,864%;

- on completion of professional activities:

MxDMnafter=170 MS, RMSSDafter=19,626 MS, AMOafter=86,915%.

Substituting the values of the indicators in differentiating functions, calculated values:

G1=-0,005(170-200)-0,031(19,626-25,721)+0,01(86,915-57,864)-0,768=-0,138545;

G2=0,032(170-200)-0,115(19,626-25,721)-0,031(86,915-57,864)-3,372=-4,531656.

The condition G1>G2, therefore, the examinee needs rapid correction of psychophysiological state. Conducted a session of aromatherapy using essential oils of peppermint, Shal�nl and lemon tarragon contributed to the normalization of psychophysiological state, positive impact on objective and subjective assessments of its performance.

The described method is verified in the process of medical support staff of facilities for destruction of chemical weapons and has found application in practice.

.

Method of determining indications for rapid correction of psychophysiological state, characterized by the fact that before, during and after professional activity register kardiointervalogrammy and determine the variation of the magnitude of the duration of RR-intervals (MxDMnto, MxDMnafter), the square root of the sum of differences of successive series of RR-intervals (RMSSDto, RMSSDafter), the amplitude of the fashion of the duration of RR-intervals (AMOtoAMOafter) and calculate the derivative of functions (G1 and G2)
G1=-0,005(MxDMnafter-MxDMnto)-0,031(RMSSDafter-RMSSDto)+0,01(AMOafter-AMOto)-0,768,
G2=0,032(MxDMnafter-MxDMnto)-0,115(RMSSDafter-RMSSDto)-0,031(AMOafter-AMOto)-3,372,
and if the value of G1 does not exceed the value of G2, we surveyed identify as requiring rapid correction of psychophysiological state, in other cases, the examinee is determined as not requiring rapid correction of psychophysiological state.



 

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FIELD: medicine.

SUBSTANCE: invention represents a method for determining a probability of preserving the myocardium following infarction by creating an admission examination-based data array of 7 peripheral blood parameters, 11 biochemical analysis parameters and 6 parameters of standard 12-lead electrocardiogram in 200 patients with the Q-myocardial infarction and 200 patients without the myocardial infarction. The parameters are stratified with respect to 7 intervals, wherein values related to the probability of preserving the myocardium following infarction are derived by calculating a ratio of the patients without myocardial infarction to all the patients with acute coronary syndrome. The probability is evaluated in a specific patient by analysing the above parameters, searching the respective intervals and values related to the probability of preserving the myocardium in the data array. Summing up the derived values enables calculating an integrated index, which is normalised, and a dimension from 0 to 100% is reduced.

EFFECT: invention enables increasing the prediction accuracy of preserving the myocardium in the patients with acute coronary syndrome.

1 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: invention relates to the field of medicine, in particular to cardiology, and can be used for determining success in recovering the sinus rhythm in patients with paroxysmal atrial fibrillation. A rhythmogram is registered and the following mathematical averaging by a "sliding window" method is realised. The coefficient of rhythm biochronological ordering is calculated by formula limmam=2n(n+1)k=0n1(k+1)ak, where lim a is the coefficient of rhythm biochronological ordering (relative units), a stands for values of R-R intervals (milliseconds), n stands for the quantity of intervals, m is the quantity of averaging cycles, k is an averaged interval number. If the value of lim a<5.5, the possibility of recovering the sinus rhythm by both a pharmacological and an electric cardioversion is lower than 10%, in case of lim a (≥5,5; ≤6,5), the possibility of recovering the sinus rhythm by the electric cardioversion is higher than 90%, with lim a>6,5 the possibility of recovering the sinus rhythm by the pharmacological cardioversion is higher than 90%.

EFFECT: method makes it possible to estimate the probability of recovering the sinus rhythm in patients with paroxysmal atrial fibrillation with high sensitivity and specificity.

3 ex

FIELD: medicine.

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3 ex

FIELD: medicine.

SUBSTANCE: patient's monitor comprising: EEG recorder (14, 20) controlling patient's (10) electrocardiographic signal (40); a secondary physiological signal monitor (16, 20) controlling a second patient's physiological signal (50) simultaneously with the EEG recorder controlling patient's electrocardiographic signal; an a alarm detector (42, 44) configured to detect the alarm on the basis of the patient's electrocardiographic signal; alarm verification device (52, 54, 56) configured to verify the alarm on the basis of pulse component regular pattern of the simultaneously controlled second patient's physiological signal; and an alarm indicator (24, 26, 58) configured to generate the perceived alarm by the alarm detector and to verify the alarm by the alarm verification device.

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FIELD: medicine.

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1 tbl, 2 ex

FIELD: medicine.

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3 ex, 6 tbl, 3 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine, labour safety, vocational selection of rescue workers. The invention can be used for vocational selection in the sectors of industry using personal protective equipment, as well as for the workers labour safety in the sectors of industry with harmful working conditions. The method involves vocational selection and duty control on the basis of electroencephalogram (EEG) values and cardiological findings. The examination is performed prior to and when using the personal protective equipment. The cardiological examination involves assessing the heart rate variability with using the amplitude-frequency spectrum Fourier analysis VLF at a vibration frequency within the range of 0.0033-0.04 Hz, LF - at a frequency of 0.05-0.15 Hz and HF - at a frequency of 0.16-0.80 Hz, and is five-staged: initial resting state, mental work load, recovery of mental work load, hyperventilation load, recovery of hyperventilation load. At the beginning, the heart rate variations and EEG are examined prior to using the personal protective equipment. If any of the five stages of the heart rate variation examination shows the pulse more than 90 beats per minute, as well as changes from the normal values of: approximating entropy - less than 180, LF - less than 6 point, an alpha wave amplitude - to 12 vibrations per second and the presence of the paroxysmal activity by EEG, the prevailing sympathetic nervous system is stated, or if any stage of the heart rate variation examination shows the pulse less than 60 beats per minute, as well as changes from the normal values of: blood pressure - more than 140/90 mmHg, VLF - more than 130 points, HF - more than 16 points, an alpha wave amplitude - less than 25 mcV, the prevailing parasympathetic nervous system is stated; a low level of adaptation to the personal protective equipment is predicted, and a rescue work is not recommended during the vocational selection; the examination is terminated. If the heart rate variation and EEG prior to using the personal protective equipment fall within the normal values, the heart rate variation when using the personal protective equipment is started with the patient examined when using the personal protective equipment and performing a cycle ergometer test, and recording the hyperadaptotic changes of the assessed values: VLF - more than 130 points in relation to the normal value when using the personal protective equipment and LF and HF vibrations; an incomplete or unfinished adaptation to the personal protective equipment, and the rescue worker is suspended from work for several hours; if VLF is more than 130 points recorded 10-15 min after activating the personal protective equipment, a good adaptation level to the personal protective equipment is predicted.

EFFECT: method enables assessing the vegetative nervous function and predicting the rescue workers' adaptation level to the personal protective equipment.

11 tbl, 5 ex

FIELD: medicine.

SUBSTANCE: cardiorhythmography is recorded during an active orthostatic test, and a heart rate variability (HRV) is analysed. During the active orthostatic test, the patient is placed in an initial horizontal position, then transferred into the vertical position, and then into the horizontal position again. If the amplitude of HF waves initially increases more than LF waves in the horizontal position by more than 30%, a prevailing parasympathetic effect is diagnosed. If the amplitude of HF and LF waves decreases after the patient is transferred into the vertical position by more than 30% of the values in the initial horizontal position, vegetative insufficiency is diagnosed. If the amplitude of HF waves decreases after the patient is transferred into the vertical position by more than 80% of the initial value in the horizontal position, a fast adjustment of the parasympathetic department to the changes is diagnosed. If the amplitude of VLF waves increases after the patient is transferred into the vertical position by more than 30% of the initial value in the horizontal position, activation of the supra-segmentary vegetative nervous system is diagnosed.

EFFECT: method provides more reliable diagnosing that is ensured by determining the mechanism of orthostatic test adaptation.

2 tbl, 2 ex

FIELD: medicine.

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EFFECT: technique enables diagnosing the extra-oesophageal manifestations of gastrooesophageal reflux disease at the early stage of the disease after the subjective manifestations have been observed.

FIELD: medicine.

SUBSTANCE: invention relates to medical equipment. An ECG monitoring system for detecting infarct-related coronary artery associated with acute myocardial infarction comprises the number of electrodes for data collection by electrical cardiac activity from various observing points spaced from the heart. An ECG data collection unit is related to the electrodes. An ECG processor responses to electrode signals to form a set of lead signals and detects ST rises in the lead signals. The display responses to the detected ST rises and graphically displays each set of the given ST rise in relation to the anatomical positions of the leads. The graphical display identifies the suspected infarct-related coronary artery or branch associated with acute ischemic stroke. The ECG signals is n-leads are received. The ECG signals are analysed for the consistency with the ST rise data. The each set of ST rises is graphically displayed in relation to the anatomical body positions. The stages of receiving and analysing are repeated some time later. The each set of ST rises derived some time later are graphically displayed and compared to the previous displayed ST rises. A comparative graphic display is used to display the time variation of a coronary disease symptom associated with the specifically identified coronary artery or branch.

EFFECT: using the invention enables reducing the length of diagnosing.

15 cl, 18 dwg

FIELD: medicine.

SUBSTANCE: assessing a risk of recurrent atrial fibrillation (AF) is ensured by determining the patient's age in years (A), the time following radio frequency ablation in months (B), postoperative inpatient recurrent atrial fibrillation (C), the degree of the aortic valve insufficiency (D), the left atrial diameter in mm (E), anti-arrhythmic therapy conducted (F) with F=l if the anti-arrhythmic therapy involves amiodarone, and F=2 if the anti-arrhythmic therapy with sotalol is conducted, the degree of the mitral valve insufficiency (J), the number of reference ablation points (I); the number of radio frequency applications (G); the radio frequency ablation type (H) with H=2 accompanying RF labyrinth, and H=3 with the radio frequency ablation of pulmonary vein basins and ganglia plexuses. The derived values are used to calculate the risk (R) of atrial fibrillation by three formulas. The highest of the three derived R values is further determined. If the highest R value has been derived by the first formula, the recurrent atrial fibrillation following the radio frequency ablation may not be predicted. The highest R value produced by the second formula enables predicting the recurrent atrial fibrillation to come during 6 months following the radio frequency ablation.The highest R value taken from the third formula shows that the recurrent atrial fibrillation is predicted to come during more than 6 months following the radio frequency ablation.

EFFECT: method enables predicting the risk of the recurrent atrial fibrillation following the radio frequency ablation in the patients, pre-selecting a set of medical products necessary for the anti-arrhythmic and anti-coagulant treatment of the patient, pre-specifying a follow-up visit schedule and additional functional diagnostic techniques and considering if the repeated radio frequency ablation is required.

2 ex

FIELD: medicine.

SUBSTANCE: invention refers to medical equipment. An electronic sphygmomanometer comprises a cuff, an inflation and pressure release unit for the cuff pressure adjustment, two pressure sensors, two generation circuits generating a rectangular signal at a pressure-dependent frequency, a generation circuit adjustment circuit ensuring passing an output signal from one of the above generation circuits, and a control circuit for generating an input rectangular signal from the circuit adjustment circuit and for calculating blood pressure at a rectangular signal frequency. The pressure sensors are connected to the cuff and matched with the generation circuits. The adjustment circuit is configured as a common one for the above generation circuits. The control circuit switches between the generation circuits by producing a signal of switching to one of the generation circuits. The control circuit generates the first signal of switching to the first generation circuit and determines the first cuff pressure dependent on the first rectangular signal frequency. The control circuit generates the second signal of switching to the second generation circuit and determines the second cuff pressure dependent on the second rectangular signal frequency. The control circuit detects if there is a failure of the above pressure sensors as shown by the first and second cuff pressure difference.

EFFECT: invention is expected to increase the measured blood pressure reliability when using more than one sensor.

4 cl, 9 dwg

FIELD: radio engineering, communication.

SUBSTANCE: invention relates to transceiver device for processing a medium access control (MAC) protocol used by a transceiver. The transceiver comprises a first antenna system for on-body communication and a second antenna system for off-body communication, the transceiver device being designed to reserve one or more data payloads for on-body communication and to allocate the first antenna system to the transceiver in the time interval occupied by said data payloads, and/or to reserve one or more data payloads for off-body communication and to allocate the second antenna system to the transceiver in the time interval occupied by said data payloads.

EFFECT: providing an optimally matched antenna system for on-body communication and off-body communication respectively, preventing collisions between data payloads on a radio channel, thereby increasing data throughput and, at the same time, reducing power consumption of the transceiver.

15 cl, 14 dwg

FIELD: medicine.

SUBSTANCE: patient's epicardial fat thickness is measured by transthoracic echocardiography by means of a sector transducer at a frequency of 2,500 MHz on a free anterior wall of the right ventricle. Pulse Doppler imaging is performed to determine the diastolic function of the left ventricle - the E/A ratio measured as a transmitral blood flow velocity in the early diastolic filling of the left ventricle (E peak) to a transmitral blood flow velocity in a left auricular systole (A peak). If the epicardial fat thickness is from 2.7 to 4.5 mm, whereas the E/A diastolic function is less than 0.80, insulin resistance is diagnosed.

EFFECT: higher diagnostic accuracy, as well as wider number of individuals, who had the insulin resistance diagnosis.

1 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine, namely to cardiology. A microphone signal, simultaneously passing through two band filters with fixed pass bands, is registered. The pass band of the first pulse-wave filter is set at 3-6 Hz. The pass band of the second filter of Korotkov′s tones is set at 40-120 Hz. Reliable Korotkov′s tones in the determination of systolic pressure are considered to be exceeding of a threshold value of the amplitude of the first filter output signal after the local maximum of the output signal of the first filter. The reliable Korotkov′s tones in the determination of diastolic pressure are considered to be exceeding the threshold value of the amplitude of the output signal of the second filter to the local maximum of the first filter output signal. The claimed method is realised due to the device, which includes an air pressure sensor in a cuff, a microphone, the first pulse-wave filter has the pass band of 3-4 Hz, the second filter of the Korotkov′s tones has the pass band of 40-120 Hz, a unit for the determination of maximal values of output signals of the filters, a unit for the selection of the threshold values of comparison of the output signals of the filters, a unit for the comparison of the output values of the output signals of the filters with the threshold values, a unit for the comparison of the moment when the threshold value of the output signal of the second filter is exceeded, with the moment of achieving the local maximum of the first filter.

EFFECT: group of inventions makes it possible to increase the reliability of measurements due to the reduction of the impact of external noise and interference, conditioned by the patient's physiological activity.

2 cl, 2 dwg

FIELD: medicine.

SUBSTANCE: invention relates to means for the estimation of energy efficiency of a cardiovascular system. The method of automatic processing of blood pressure signals contains stages at which: a detected pressure signal P(t) for one or more heart contractions is discretised, with each heart contraction starting at an initial moment, coinciding with the moment of the diastolic pressure, and finishing at the last moment, coinciding with the moment of the following diastolic pressure, and containing a dicrotic point, the morphology of a discretised pressure signal P(t) for each heart contraction is analysed and separated, the moment and value of pressure in one or more characteristic points of the signal P(t) are determined. For each heart contraction a value of energy efficiency is determined by the determination of the impedance Zd-D(t) of a direct dynamic wave of pressure for each of one or more characteristic points, except the point of an initial diastolic pressure, and the impedance ZD of a direct pressure wave is determined by the addition with alternating signs of values of the impedances Zd-D(t) of the direct dynamic pressure wave, ordered in accordance with the direct time order, starting with the initial moment of the analysed heart contraction, to a dicrotic moment, the dynamic reflected impedance Zd_R(t) is determined for each of one or more characteristic points and the value of impedance ZR of reflected pressure waves is determined, energy efficiency is determined as a ratio between the impedance ZD of the direct pressure wave and the impedance ZR of the reflected waves RES=ZD/ZR. The method is realised by an automatic device for processing the blood pressure signal with the application of a storage medium, which contains stored software.

EFFECT: application of the invention makes it possible to increase the reliability of energy efficiency estimation.

14 cl, 6 dwg

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine. A device used in the group of inventions comprises an input interface designed to supply signals from at least two sensors for at least two individual's positions, including the blood-dependent signals, from the first signal when the individual is found in the first position; the blood-dependent signals from the first sensor when the individual is found in the second position; the blood-dependent signals, from the second sensor when the individual is found in the first position; and the blood-dependent signals, from the second sensor when the individual is found in the second position; as well as an operational circuit designed to determine and output measures by combining the supplied signals according to the pre-set calibration data.

EFFECT: group of inventions enables calculating the measures by experimental tests.

22 cl, 5 dwg, 2 tbl

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine. An electronic sphygmomanometer contains a cuff, a unit for air filling and release, a pressure detection unit and a unit of arterial pressure calculation. One or two sensors of the pressure detection unit of are located on the first main surface of an internal circuit board. Air channels of the pressure sensors protrude on the second main surface, which is an opposite side of the internal circuit board from the first main surface. An air tube of the pressure sensors is connected with air channels. A branching air tube branches from a cuff air tube and is connected with the air tube of the pressure sensors. The air tube of the pressure sensors has connecting heads of the first and second air channels respectively, connected with the first and second air channels respectively. The internal circuit board has the first and the second protecting plates, which are located at the specified distance from the second main surface and in which respectively provided are the first and the second holes, which bring the first and the second air channels respectively on the side of the second main surface. At least one protruding element of the connecting heads of the first and the second air channels respectively mesh with the internal surface of the protective plates in the holes, when external surfaces of the connecting heads are connected with the air channels.

EFFECT: application of the inventions will make it possible to increase the accuracy of arterial pressure measurement.

5 cl, 17 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medical equipment. An electronic sphygmomanometer comprises a cuff, a cuff inflation and pressure release unit, a cuff inflation pressure monitoring unit and a blood pressure determination unit. The pressure monitoring unit comprises the first and second pressure sensors, which are provided on the first primary surface of an internal printed board. The internal printed board is integrated inside the main part of the body and inclined to a mounting pad. The first and second pressure sensors are arranged along the direction perpendicular to the inclination of the internal printed board.

EFFECT: using the invention is supposed to increase the reliability of the measured blood pressure by ensuring the peripheral structure comprising the pressure sensors.

3 cl, 17 dwg

FIELD: medicine.

SUBSTANCE: patients are assessed individually to establish the fact of chronic cardiac insufficiency (CCI) suffered by detecting: age, height, weight, Quetelet index, Brock constant, systolic blood pressure, diastolic blood pressure, triglycerides, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, low-density lipoprotein cholesterol to total cholesterol ratio, very low-density lipoprotein cholesterol, high-density lipoprotein cholesterol to low-density lipoprotein cholesterol ratio, sum of the very low-density lipoprotein cholesterol and high-density lipoprotein cholesterol to low-density lipoprotein cholesterol ratio, atherogenic index, alanine aminotransferase, aspartate aminotransferase, aspartate aminotransferase to alanine aminotransferase ratio, lactate dehydrogenase, glucose, α-amylase, total protein, albumin, uric acid, carbamide, creatinine, creatinine kinase, alkaline phosphatase, total bilirubin, conjugated bilirubin, ADP-induced thrombocyte aggregation, thrombocyte count, mean thrombocyte volume, erythrocyte count, mean erythrocyte volume, erythrocyte volume distribution, haematocrit, haemoglobin, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, leukocyte count, segmented neutrophil percentage, eosinophil percentage, basophile percentage, lymphocyte percentage, monocyte percentage and displacement constant. The derived discriminator functions are used to establish the fact of the absence of CCI, the first stage of CCI, or the second stage of CCI.

EFFECT: method enables assessing the patients to establish the fact of CCI by determining the significant parameters.

3 dwg, 2 tbl, 1 ex

FIELD: medicine.

SUBSTANCE: method involves recording heart beat rate and systolic arterial blood pressure before and after two-stage exercise stress. The first stage is of 50 W within 3 min and the second one is of 75 W during 2 min. Patient rest pause is available between loading stages to recover initial heart beat rate. Prognostic estimation of cardiopulmonary complications is carried out with mathematical formula applied.

EFFECT: reduced risk of complications in performing tests.

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