Method of operative screening diagnostics and correction of person's functional state by means of hardware-software complex "rofes"

FIELD: medicine.

SUBSTANCE: invention relates to medicine, electric puncture screening-diagnostics and can be used in different fields of medicine, psychology, sport, where monitoring of person's state for long-term time period with operative correction of their indices is required. Electric puncture impact on person's corporal biologically active points (BAP) by means of hardware-software complex with application of positive and negative polarities, measurement of electric skin resistance (ESR) in BAP and further analysis of results by mutual location of ESP profiles are performed. Additionally carried out is spectral diagnostics, including analysis of spectral Fourier series of frequency changes, when measured point is adapted to provoking impact of measuring current, with further formation by means of computer programme of frequency therapeutic module, consisting of patient's functional frequencies, isolated from their frequency spectrum in case when they do not correspond to their standard indices. Frequency therapeutic module is aimed at diagnosed points to carry out operative correction of functional state of organs and systems. Analysis of spectrum of frequency characteristics is realised in range 0.015-100 Hz with discreteness 0.015. Frequency therapeutic modules are formed at specified time interval of 1 minute and longer depending on patient's state. Operation of diagnostics and correction of functional state of organs and systems is realised by cycle with period (1…N) depending on patient's state.

EFFECT: method provides increase of diagnostics accuracy due to increased quantity of diagnostic characteristics and optimal reduction of noise component, with reduction of quantity of diagnosed points, which provides reduction of diagnostics time, increase of long-term monitoring efficiency due to possibility of specifying diagnostic cycles.

5 cl, 5 dwg

 

The invention relates to medicine, namely to electro-screening-diagnosis and can be used in various fields of medicine, psychology, sports that require monitoring of the human condition for a long period of time with surgical correction of the indices.

In electro-screening-diagnosis currently known methods of determining the functional state of man - Voll method and Nakatani method, which differ in the set of points of the study, the operating parameters of measuring devices and system analysis of the data.

Voll method is based on measuring the conductivity of a section of the Meridian and the dynamics of establishing current at acupuncture points. Using weak constant currents (up to 1.5 μa) and voltage to 1.5-2 In (D. M. Tabeeva, Manual of acupuncture, 1982, p. 152).

The disadvantage of this method is the large measurement time 30 to 50 minutes, which increases the duration of the survey.

The method of Nakatani Japanese scientist is developed by the author Ryodoraku theory. (D. M. Tabeeva, Manual of acupuncture, 1982, p. 154-160). According to this theory there is a close relationship between the functional state of internal organs and the electrical conductivity of the skin surrounding l�ments corresponding meridians. These lines of changing its electrical conductivity at the changing roles of related agencies, Nakatani called Ryodoraku, dividing them into two groups of six points each: hand and foot control.

The disadvantages of Nakatani method include the following: electro-impact on BAP is a unipolar current (negative), the exposure time of the BATH is limited to a fixed period 2, the passive electrode placed in the study in the patient's arm, gives a huge error in the measurement of the BAHT as a result of density squeezing his patient. These three parameters contribute to low reliability of the diagnosis. In addition, the current impact on BAT-200 μa, has a too high value, which causes discomfort in sensitive patients. The interpretation of the results of measurement, only limited clinical component, reduces the degree of reliability of the diagnosis. The lack of a common integral characteristics, expressed in numeric values of the physiological and psychological state of the patient, reduces the information content of the measurements and the accuracy of diagnosis.

The closest analogue adopted for the prototype is a method of electro-determine the functional state of the person (screening-diagnosis) expert evaluation (ROFES-Diagnostics�stick), including the effects of electroacupuncture on the corporal BAHT 12 main paired meridians of the human microcurrent positive and negative polarities to the time when the ripple voltage during a time interval of 0.2±0.01 s will be the amplitude of ≤5 mV, the measurement of electrical skin resistance at the points of the BAHT, drawing on a pie chart of the results of the measurement and subsequent analysis of results according to the relative positions of the profiles relative to EX their average constituent by the total area, they described in accordance with the rules of the Eastern concept of "Wu xing" (RU Pat. No. 2202278, op. 20.04.2003).

In the prototype diagnosed by value is just the electric skin resistance (EX), which reduces the efficiency of diagnostics of functional state of organism

In addition, in the method diagnosed 12 paired meridians of the human body and/or the reaction of BAPs on skin areas located above the spinous processes of the spine is carried out according to the scheme of BAPs in the sequence C1-C7, Th1-Th12, L1-L5, S1-S5, or in the micro system su-Jok and time of diagnosis of these cutaneous areas is a fairly long period, namely from 4 min to corporal meridians to 15 minutes in the aggregate on other listed areas.

The problem to be solved by the claimed invention, the tri�Xia improving the efficiency of diagnostics of functional state of the organism, by increasing the number of diagnostic characteristics, decrease the time of diagnosis.

The technical result of the invention is achieved by the fact that in addition to obtaining and analyzing diagnostic characteristics of electrical skin resistance (EX) analysed the frequency spectrum obtained by the decomposition in Fourier series curve created in the process of adapting biologically active points (BAP) or skin area corresponding to projection of an organ, to provoke the impact of the current direct and inverse conductivity for operational correction of the functional state of the organism with frequencies of the patient, isolated from its frequency spectrum in case of discrepancy between their regulatory reasons (the concept of deviations in the frequency spectrum below).

Reducing the time of diagnosis is achieved by reducing the number of diagnosed BAPs or skin zones to at least one.

To solve the problem in the method of screening diagnostics of the functional state of the person by means of hardware-software complex, which includes the effects of electroacupuncture on corporal biologically active points (BAP) of a person microcurrent positive and negative polarities, the measurement of electrical skin resistance (EX) in the BAPs and after�following analysis of the results according to the relative positions of profiles EX, according to the invention, in parallel with the above operations further comprising spectral diagnostics, including analysis of spectral Fourier series frequency changes that occur during adaptation of the measured points the BAT to provoke the impact of the measuring current, with the subsequent formation using a computer program frequency treatment module consisting of a patient's functional frequencies extracted from its frequency spectrum in case of discrepancy between their regulatory indicators, then the specified frequency therapeutic module is sent to the diagnosed point for the surgical correction of the functional state of organs and systems, the analysis of the spectrum of frequency characteristics is carried out in the range of 0.015-100 Hz with a resolution of 0.015.

Method screening-diagnostics of functional state of the person is carried out using hardware-software complex "ROFES-MONICOR".

Spectral diagnostics is carried out, at least from one point of the BATH or skin areas of the human body.

Frequency of therapeutic modules form at a predetermined time interval of 1 min or more depending on the patient's condition.

Diagnosis and correction of functional state of organs and systems are repeated in a cycle with a period of (1...N) depending on the patient's condition.

Diagne�stico-correction cycle is performed by the iteration rule, where each subsequent diagnostic operation takes into account the results of previous diagnostic operations and forms in connection with this new frequency module, which will include the frequency of the spectral Fourier series of this diagnostic operation.

The method is carried out using hardware-software complex electro-diagnostics ROFES (developed by Ural NPP "ALTHEIM" Ekaterinburg, the certificate of state registration of computer programs No. 970188 from 28.04.1997 G., the Registration certificate of the Federal service for supervision in the sphere of health and social development No. SDF 2009/04341 of 17 February 2009 on the resolution to the manufacture, sale and use in the territory of the Russian Federation complex ROFES). Version ROFES - monitoring of adaptation and correction of States "MONICOR" - a rapid method of functional diagnostics and correction of States.

The method is illustrated by drawings:

Fig. 1 - shows a graph of the current curve with frequency changes (fluctuations) in the adaptation of the measured point BAT provoking to current direct and inverse conductivity;

Fig. 2 is a graph showing the frequency spectrum of BAHT Meridian, such as lungs;

Fig. 3 is a graph showing changes of the frequency spectrum BAHT Meridian to the oscillating signal points that characterize what-if�about deviations in the system of bodies, the responsibility of this Meridian;

Fig. 4 profiles EX.

Before research is programmed total session time, time of diagnosis and time correction. The operator of the computer program sets a certain period of time (total session time) required to conduct the study, set the iteration (set of diagnostic operations, where each operation uses the results of the previous), i.e. the number of cycles (diagnostics plus correction). Each stage of the iteration provides surgery diagnosis with BAT or skin zones, mathematical processing of spectral data of a Fourier series with the formation frequency of therapeutic module by selecting frequency therapeutic module correction and automatic correction of the functional state of the diagnosed organ systems therapeutic frequencies module, then diagnosis with BAT and so on in a loop until the total time of the study patient.

The total time of the session chosen in the time interval 1 min - 24 h depending on the severity of the condition of the human body or research purposes.

In diagnostic and corrective cycle diagnosis is performed during the time required for obtaining spectral Fourier series from 0,015 Hz to 100 Hz with a resolution of 0.015 (currently in those�Linux 50, but may be reduced to 15 sec depending on hardware complex "ROFES-MONICOR"), the correction between diagnostic operations for 1 min or more depending on the patient's condition. Each frequency, otsilindrovannoy in frequency therapeutic module, sets the time of its impact with 10 or more depending on the patient's condition.

For the flow of electric current through point or diagnosed skin areas closed electrical circuit, and therefore biologically active points of a skin area corresponding to projection of an organ, are disposable cardioelectric or konechnostei cardioelectric with absorbent material (e.g. cotton wool) soaked in saline solution. Select the type of cardioelectric depends on the topology of points (for example, konechnostey cardioelectric not be installed on the BATH spins) Cardioelectric sensor attached to the complex "ROFES-MONICOR".

Spectral diagnostics can be performed as with a single BAT or skin area corresponding to projection of an organ, and with a pair of biologically active points of the main paired meridians of the human body P, G, E, RP, C, IG, V, R, MS, TR, VB, F, or prednisone.diego and zadnesheynyh Meridian or projection zones above the spinous process of vertebra C1-C7, Th1-Th2, L1-L5, S1-S5 PU�eat overlay disposable cardioelectric, intended for cardiac monitoring, in the case of pairs of main meridians, or by applying a one-time cardioelectric on BAT prednisone.diego or shinesensational meridians, or on the projection points on the spinous processes of the spine with a passive fixation electrode soaked with the saline swab on thenar of the hand of the patient (the elevation of the muscles of the thumb). Excluded points on the scalp, where is set by the operator sensor complex "ROFES-MONICOR" soaked in saline.

Process is initiated.

Exercise electroacupuncture effects on corporal biologically active points (BAP) or the skin areas of the human body microcurrent positive and negative polarities U=4V, the current is 60 μa.

Next, perform measurement of electrical skin resistance at one or more points of the BAHT under control of a hardware-software complex "ROFES-MONICOR" with subsequent analysis of the results of measurements at selected points on the relative positions of the profiles of the EX (Fig. 4).

At that point adapts to provoke currents smoothly and abruptly - with wave fluctuations (Fig. 1). Therefore, in parallel analyzed the spectral range Fourier frequency changes that occur during adaptation of the measured point-to-provoking impact� measuring current in these measured points in the range of 0.015-100 Hz with a resolution of 0.015.

The computer program performs the memorization of these oscillatory processes and their spectral processing.

Spectral analysis of the Meridian system based on spectrum analysis of frequency characteristics measured BAHT as a result of provoking effects of the current. The analysis is carried out by mathematical methods, i.e., the decomposition of the signal (vibration) BAP measured in the Fourier series and further formalized analysis of the obtained characteristics in the range of 0.015 Hz to 100 Hz with a resolution of 0.015.

Fig. 2 shows the frequency spectrum of BAHT Meridian, such as the lungs. Each column (harmonica) on the chart represents a specific frequency included in the formation of the oscillating signal point in provoking result of the impact of the measuring current (oscillation signal of the measured point can be seen in the measurement process on the indicator showing this process). On the abscissa (horizontal axis) presents the names of the frequencies (in our case the low frequencies from 0.015 to 100 Hz). The ordinate (vertical axis) is represented by the magnitude of energy intensity of these frequencies (harmonics - columns).

For normal functioning of a living object or system, the response to the provoking impact shock, that is a normal adaptation to current, should look at the spectral graph in the form of successive reduction of columns (harmonics) from the beginning of the graph to its end at the x-axis, that is, the fading process. This decrease looks like a kind of curve is closer to the Exhibitor ("Exhibitor drop-down"), if all the peaks are joined by a line. Every next column is smaller than the previous one from left to right by a certain value, i.e., a negative increment (-Δ-Delta) (Fig. 2).

To the oscillating signal point describing any deviations in the system of bodies which are the responsibility of the diagnosed point or a skin area, a characteristic change of the frequency spectrum. The graph can receive "emissions", that is, the rule is violated successive reduction of the values of columns (the rule "drop-down exhibitors"). Any harmonica (column) describing the energy intensity of a specific frequency will have a value higher than the previous harmonic, that is, the positive increment (+Δ-Delta).

In the Fig. 3 we can see a clear trend of violation of the rules "drop-down exhibitors" at the beginning of the spectrum graph of Meridian TRd (Fig. 3).

Meridian system is a system of communicating vessels (or conductors), which will reflect in any point of the system frequency response of the organs and systems through which the meridians, according to the laws of electrical engineering, where in an electrical circuit can be defined�you in any part of all frequency interference, present from the radiation of all of its constituent elements and others electrical appliances. Accordingly, the spectral Fourier series after processing oscillatory signals obtained during the measurement of the BAT, makes it possible to analyze the harmonics of the respective frequencies, which are the emissions (positive increment), about the state of the organs for which these frequencies are described in the methods of R. Voll, P. Schmidt. (A. V. Samokhin, Yu V. Kiseleva T. L. President. Electropuncture diagnostics and therapy by the method of R. Voll. Moscow "IMEDIS". 1995)

Further, a computer program generates a frequency therapeutic module for correction of the functional state of organs and systems according to spectral diagnostics, consisting of those patient's functional frequencies that do not satisfy the rule "drop-down exhibitors" on the measurement result of the BAHT, the module breeding values of those frequencies that have a positive increment. Additional diagnostic data of the functional state of organs and systems increases the accuracy of diagnosis and meridional enhances the efficiency of correction of functional organs and systems with frequency offset according to diagnosis, as they will impact only the functional (native) frequency of the patient, not with�testout regulatory indicators rules "drop-down exhibitors", shown in the graph.

As an example implementation of the inventive method presents the monitoring of the patient's adaptation to any methods of external influence (sports, medical, etc.) with automatic calculation of changes in the activation of all physiological systems and functional state of the organism at all the studied time period.

1. Programmed the session, time of diagnosis and the time of correction.

For example: total time 40 min session, diagnosis is carried out every three minutes, the correction of the functional state of the diagnosed organ systems for 3 min between diagnosis.

2. On two points, for example Pericardium Meridian MS, MS (left and right) are disposable cardioelectric. You start a process in a computer program "ROFES-MONICOR".

3. Automatically under program control is performed electroacupuncture effects on selected corporal biologically active points (BAP) of the Pericardium Meridian - MS person microcurrent positive and negative polarities, U=4V, the current is 60 μa.

4. Is the measurement of electrical skin resistance at two points BAT running hardware-software complex "ROFES-MONICOR" with subsequent analysis of the results of measurements at selected points on the relative positions of the profiles of FORMER.

6. Then use a computer program to form a frequency therapeutic module, consisting of a patient's functional frequencies extracted from its frequency spectrum, which are not normative. That is, the oscillating signal of the point describing any deviations in the system of bodies which are the responsibility of the Meridian, the peculiar change in the frequency spectrum. The graph can receive "emissions", that is, the rule is violated successive reduction of the values of columns (the rule "drop-down exhibitors"). Any harmonica (column) describing the energy intensity of a specific frequency will have a value higher than the previous harmonic, that is, the positive increment (+Δ-Delta).

7. Next, the program automatically sends a frequency therapeutic module in testing point for correction of the functional state of organs and systems within 3 min and monitors the results of the correction.

Next 3 minutes the process is repeated from step 3 is carried out the following examination with get�of integrated assessment of functional status and a new frequency therapeutic module with functional frequencies, which are formed based on previous exposure, respectively, are optimized because the body has been the response, both on the process of external influence, but also to the correction process of the previous frequency module.

The process is carried out on the cycle after 3 min before the end of the total time of diagnosis and correction, in this case, 40 min.

The operator visually sees the conclusions of the computer program in the form of physiological response systems on the whole process and gets them in the entire session in the form of a traffic light - red, yellow, green. All this is saved in the database for further analysis.

Achieved technical result of the claimed invention are as follows:

- increase of efficiency of diagnostics of functional state of the organism by increasing the number of diagnostic characteristics, namely, in addition to receiving electrical skin soprotivlenie (EX) analyzes the frequency spectrum obtained by the decomposition in Fourier series curve obtained in the process of adaptation points BAHT or skin area to provoke the impact of the current direct and inverse conductivity in the frequency range from 0, 015 to 100 Hz with a resolution of 0.015;

- reducing the number of points or diagnosed skin areas to a single point BATH or skin area that leads to the reduction diagnostic�Tiki functional state.

- increase the effectiveness of monitoring the functional state of the organism at the expense of setting up cycles of repetition of the diagnostic operation for a long period of time - to day.

- create opportunities to use the method not only for diagnosis of the functional state of the human body but also for correction of the functional state of the organism with frequencies of the patient, isolated from its frequency spectrum in case of discrepancy between their normative statements.

1. Method operational screening-diagnostics of the functional state of the person by means of hardware-software complex, which includes the effects of electroacupuncture on corporal biologically active points (BAP) of a person microcurrent positive and negative polarities, the measurement of electrical skin resistance (EX) in the BAHT and the subsequent analysis of the results according to the relative positions of profiles EX, characterized in that in parallel with the above operations further comprising spectral diagnostics, including analysis of spectral Fourier series frequency changes that occur during adaptation of the measured point-to-provoking effects of the measuring current, with the subsequent formation using a computer program frequency therapeutic module, consisting of functionalityto patient isolated from its frequency spectrum in case of discrepancy between their regulatory indicators, then the frequency of therapeutic module is sent to the diagnosed point for the surgical correction of the functional state of organs and systems, the analysis of the spectrum of frequency characteristics is carried out in the range of 0.015-100 Hz with a resolution of 0.015.

2. A method according to claim 1, characterized in that the frequency of therapeutic modules form at a predetermined time interval of 1 min or more depending on the patient's condition.

3. A method according to claim 1, characterized in that the spectral diagnosis is performed with at least one biologically active points (BAP) or skin area corresponding to projection of an organ of the human body.

4. A method according to claim 1, characterized in that the operation of the diagnosis and correction of functional state of organs and systems is carried out on a cycle with a period of (1...N) depending on the patient's condition.

5. A method according to claim 1, characterized in that the diagnostic-remedial process is carried out according to the rule of iteration, where each subsequent diagnostic operation takes into account the results of previous diagnostic operations and forms in connection with this new frequency module, comprising the frequency of the spectral Fourier series of this diagnostic operation.



 

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2 dwg, 1 tbl

FIELD: medicine.

SUBSTANCE: one should measure electric impedance of patient's middle ear. Electrodes should be applied in three localizations: auditory canal, anterior end of lower nasal concha and frontal skin. Electric impedance should be measured at the frequencies of sinusoidal signal being equal to 10, 30, 250 and 1000 Hz, the data obtained should be compared by values of electric impedance in the given area (middle ear) in the group of healthy patients. This method provides the chance to obtain comparative data for diagnostics of middle ear diseases.

EFFECT: higher accuracy of evaluation.

2 ex

FIELD: medicine; medical engineering.

SUBSTANCE: method involves doing multi-channel recording of electroencephalogram and carrying out functional tests. Recording and storing rheoencephalograms is carried out additionally with multi-channel recording of electroencephalogram synchronously and in real time mode in carotid and vertebral arteries. Electroencephalograms and rheoencephalograms are visualized in single window with single time axis. Functional brain state is evaluated from synchronous changes of electroencephalograms, rheoencephalograms and electrocardiograms in response to functional test. The device has electrode unit 1 for recording bioelectric brain activity signals, electrode unit 2 for recording electric cardiac activity signals, current and potential electrode unit 3 for recording rheosignals, leads commutator 4, current rheosignal oscillator 5, synchronous rheosignal detector 6, multi-channel bioelectric brain activity signals amplifier 7, electrophysiological signal amplifier 8, demultiplexer 9, multi-channel rheosignal amplifier 10, multi-channel analog-to-digital converter 11, micro-computer 12 having galvanically isolated input/output port and personal computer 13 of standard configuration.

EFFECT: enhanced effectiveness of differential diagnosis-making.

11 cl, 6 dwg

FIELD: medical engineering.

SUBSTANCE: device has acting upon skin between electrodes with DC potential of given magnitude for producing temporary breakdown. Skin impedance is measured between measuring electrode first negatively polarized relative to control electrode and the control electrode, and then, DC current resistance is measured once more by means of measuring electrode positively polarized relative to the control electrode. Ratio of the obtained values is used for determining internal organ health state, corresponding to skin area.

EFFECT: enhanced accuracy of diagnosis.

11 cl, 14 dwg, 2 tbl

FIELD: poultry science.

SUBSTANCE: the present innovation deals with visual evaluation in chicken followed by testing them by the value of bioelectric potential. Chickens with bioelectric potential being significantly higher against average values are considered to be stress-resistant ones and those with bioelectric potential being significantly lower against average values in concrete population are concluded to be stress-sensitive ones. The method is very simple in its implementation and efficient for large-scale selection in poultry on stress-resistance.

EFFECT: higher efficiency.

1 cl, 2 dwg, 2 ex, 4 tbl

FIELD: medicine.

SUBSTANCE: the method deals with measuring geometric body size and electric impedances of patient's hands, body and legs at their probing with low- and high-frequency current due to current and potential electrodes applied onto distal parts of limbs, and, thus, detecting extracellular, cellular and total volumes of liquid in patient's hands, body and legs. While implementing the method one should additionally apply current electrodes onto left-hand and right-hand parts of neck, and potential electrodes - onto distal femoral parts. Body impedance (Zb) should be measured due to successive measuring the impedance of its right-hand Zrb and left-hand Zlb parts at probing current coming between electrodes of similar sides of patient's neck and legs to detect Zb, as Zb = Ѕ x (Zrb + Zlb), impedance of legs Zl should be detected due to measuring femoral impedance Zf and that of shins Zs, as Zl = Zf + Zs. At detecting the volumes of liquid in body and legs one should apply measured values of Zb and Zl, moreover, as geometric body size one should apply the distance against the plane coming through the upper brachial surface up to the middle of radiocarpal articulation in case of patient's hand being along the body.

EFFECT: higher accuracy of detection.

5 dwg, 2 ex, 3 tbl

FIELD: medicine; medical engineering.

SUBSTANCE: method involves applying electrodes to injured extremity tissue under study. The electrodes are arranged in diametrically opposite points of horizontal plane transaction to extremity surface. Two electrodes are applied to the other extremity. The electrodes are arranged in diametrically opposite points of horizontal plane transaction to extremity surface. An initial point is selected relative to which pairs of electrodes are equidistantly arranged on the extremity. Active and reactive impedance components are measured at the places of electrodes positioning. Viability condition of the injured extremity tissue under study is diagnosed depending on ratio of reactive to active impedance component on injured and intact extremity and difference between reactive impedance component on injured and intact extremity. Device has transducer unit, computer and unit for processing signals having interface units, central subscriber station, autonomous transmission center, commutator which input is connected to transducer unit output and commutator output is connected to central subscriber station input, the first input is connected to autonomous transmission center output.

EFFECT: high accuracy in diagnosing biological object condition.

5 cl, 5 dwg, 4 tbl

FIELD: medicine, psychotherapy.

SUBSTANCE: the method deals with correcting neurological and psychopathological disorders with anxiety-phobic symptomatics due to individual trainings. The method includes evaluation of body reaction to stimulating signals, seances of individual training performed due to the impact of two quasiantipodal stimulating signals of similar physical modality applied in time of sporadic character, and as a signal one should present biological feedback for the altered value of physiological parameter adequately reflecting body reaction to the impact of stimulating signal. At the first stage of training it is necessary to achieve body adaptation to the impact of quasiantipodal stimulating signals, at the second stage it is necessary to obtain conditional reflex for one out of stimulating signals, for this purpose one should accompany this stimulating signal with discomfort impact, during the third stage, finally, due to volitional efforts one should suppress body reaction to stimulating signal. The devise suggested contains successively connected a transformer of physiological parameter into electric signal and a bioamplifier, an analysis and control block with a connected block to present the signals of biological feedback, a block for presenting discomfort impact, an indication block and that of forming and presenting quasiantipodal stimulating signals. The innovation enables to have skills to control one's emotions, decrease sensitivity threshold to environmental impacts and learn to how behave during stress situations.

EFFECT: higher efficiency of training.

15 cl, 8 dwg

FIELD: medicine; medical engineering.

SUBSTANCE: method involves recording multichannel electroencephalogram, electrocardiogram record and carrying out functional test and computer analysis of electrophysiological signals synchronously with multichannel record of electroencephalogram and electrocardiogram in real time mode. Superslow brain activity is recorded, carotid and spinal artery pools rheoelectroencephalogram is recorded and photopletysmogram of fingers and/or toes is built and subelectrode resistance of electrodes for recording bioelectrical cerebral activity is measured. Physiological values of bioelectrical cerebral activity are calculated and visualized in integrated cardiac cycle time scale as absolute and relative values of alpha-activity, pathological slow wave activity in delta and theta wave bandwidth. Cerebral metabolism activity dynamics level values are calculated and visualized at constant potential level. Heart beat rate is determined from electrocardiogram, pulsating blood-filling of cerebral blood vessels are determined from rheological indices data. Peripheral blood vessel resistance level, peripheral blood vessel tonus are determined as peripheral photoplethysmogram pulsation amplitude, large blood vessel tonus is determined from pulse wave propagation time data beginning from Q-tooth signal of electrocardiogram to the beginning of systolic wave of peripheral photoplethysmogram. Postcapillary venular blood vessels tonus is determined from constant photoplethysmogram component. Functional brain state is determined from dynamic changes of physiological values before during and after the functional test. Device for evaluating functional brain state has in series connected multichannel analog-to-digital converter, microcomputer having galvanically isolated input/output ports and PC of standard configuration and electrode unit for reading bioelectric cerebral activity signals connected to multichannel bioelectric cerebral activity signals amplifier. Current and potential electrode unit for recording rheosignals, multichannel rheosignals amplifier, current rheosignals generator and synchronous rheosignals detector are available. The device additionally has two-frequency high precision current generator, master input of which is connected to microcomputer. The first output group is connected to working electrodes and the second one is connected to reference electrodes of electrode unit for reading bioelectrical cerebral activity signals. Lead switch is available with its first input group being connected to potential electrodes of current and potential electrodes unit for recording rheosignals. The second group of inputs is connected to outputs of current rheosignals oscillator. The first group of outputs is connected to current electrodes of current and potential electrodes unit for recording rheosignals. The second group of outputs is connected to inputs of synchronous detector of rheosignals. Demultiplexer input is connected to output of synchronous detector of rheosignals and its outputs are connected to multichannel rheosignals amplifier inputs. Outputs of multichannel bioelectrical cerebral activity signals amplifier, multichannel rheosignals amplifier and electrophysiological signal amplifier are connected to corresponding inputs of multichannel analog-to-digital converter. Microcomputer outputs are connected to control input of lead switch, control input of multichannel demultiplexer, control input of multichannel analog-to-digital converter and synchronization inputs of current rheosignals oscillator and synchronous detector of rheosignals. To measure subelectrode resistance, a signal from narrow bandwidth current generator of frequency f1 exceeding the upper frequency fup of signals under recording is supplied. A signal from narrow bandwidth current generator of frequency f2≠ f1>fup is supplied to reference electrode. Voltages are selected and measured at output of each amplifier with frequencies of f1, f2 - Uf1 and Uf2 using narrow bandwidth filtering. Subelectrode resistance of each working electrode is determined from formula Zj=Ujf1 :(Jf1xKj), where Zj is the subelectrode resistance of j-th electrode, Ujf1 is the voltage at output from j-th amplifier with frequency of f1, Kj is the amplification coefficient of the j-th amplifier. Subelectrode resistance of reference electrode is determined from formula ZA=Ujf2 :(Jf2xKj), where ZA is the subelectrode resistance of reference electrode, Ujf2 is the voltage at output from j-th amplifier with frequency of f2, Jf2 is the voltage of narrow bandwidth current oscillator with frequency of f2.

EFFECT: wide range of functional applications.

15 cl, 10 dwg

FIELD: medical engineering.

SUBSTANCE: device has divider, comparison unit, oscillator, acoustic radiator, controllable current source, stable constant voltage source, perspiration equivalent unit, key member, illumination source, conductivity transducer having two electrodes, the first commutator, delay unit, trigger, inverter, discharge unit, the second commutator and feeding voltage availability indicator unit. The first delay unit inputs and the first commutator inputs are connected to comparison unit output. The first commutator input is connected to the first oscillator input which delay unit, trigger and inverter are connected in series. Inverter output is connected to the second input of the first and the second commutator. The first input of the second commutator is connected to the other conductivity transducer electrode and its output is connected to device body via resistor.

EFFECT: reduced current intensity passing through patient skin; excluded negative influence upon skin during prolonged operation time on patient arm during hypoglycemia attack; low power consumption.

2 cl, 4 dwg

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