Method of improving functional-aesthetic results of plastic surgery of post-traumatic eyelid deformations
SUBSTANCE: to improve functional-aesthetic results of the plastic surgery of post-traumatic eyelid deformations, starting from 7-8 day from the moment of carrying out blepharoplasty of the post-traumatic cicatrical eyelid deformation, immediately after the removal of operational sutures, on the operated zone of the eyelid performed is a procedure of magnetic-photophoresis of a medical solution, made from 3000 ME of longidaze, 3 ml 25% solution of dimethylsulphoxide and 1 ml 0.25% solution of derinate, with 2 ml of the prepared solution being applied on an autodermal transplant and healthy skin surrounding it, with up to 1 cm indent from the wound edge, after 3-5 minutes a gauze pad, soaked with 2 ml of the remaining prepared solution, is applied on the processed surface of skin with the further 10 minute impact by a contact method by a travelling pulsed magnetic field of the apparatus "AMO-ATOS" with the frequency of pulse consecution of 5-10 Hz. Then, after the pad is removed, without the time interval, borders of the autodermal transplant and healthy skin closing are processed by infrared laser irradiation of a range of 0.89 mcm of the apparatus UZOR-2K with the frequency of the pulse repetition rate of 1500 Hz, in accordance with a contact labile method, 1 minute on each field, with carrying out 1 procedure daily for 10 days.
EFFECT: improvement of the quality of skin transplant engraftment, absence of secondary eyelid deformations, and reduction of the post-operational treatment duration.
1 tbl, 2 ex
The invention relates to medicine, namely to ophthalmology, and is intended to improve the results of plastic surgery post-traumatic deforming scarring of the eyelids.
Plastic surgery of the eyelids (blepharoplasty) post-traumatic deforming scarring of the eyelids is one of the hardest sections in ophthalmic surgery. Standard surgical methods of replacing tissue defects of the eyelids after removal of scars local or free skin and skin and fascial flaps due to inadequate connective tissue response to operative trauma often lead to the formation of hypertrophic scars, reduce dermal graft, with the development of secondary cicatricial deformities of the eyelids, requiring repeated surgical interventions (Korablev, S. B. Experimental study of the development of autoimmune reactions and their influence on engraftment of transplants for multiple autoplasty of the skin: author. dis. ... candidate. Biol. of Sciences / Institute of the clinical hospital. immunology of Academy of medical Sciences of the USSR. - Novosibirsk, 1988,, 22 p)
General background of unsatisfactory results of blepharoplasty cicatricial eyelid defects are reduced local immunity, intensification of lipid peroxidation, neurotrophic disorders, maintenance of chronic inflammation and causing a disconnect between the percent�themselves of collagen formation and collagenolysis (A. A. Delvig A study of the metabolism of collagen in hypertrophic scars and keloids. // Bulletin of the Russian Academy of medical Sciences. - 1995. - No. 12. - Pp. 41-45.).
Among medicines, limiting excessive formation of connective tissue structures and their fibrilization include glucocorticoids (Astakhov Yu. s., Egorov E. A., T. V. Stavitsky Oftalmologia. A guide for physicians / GEOTAR-MED, 2004. - P. 468). However, their disadvantages include the ability to:
- decrease local immunity;
- increase intraocular pressure;
- to break skin pigmentation;
- to induce the formation of telangiectasias.
Classic means preventing excessive formation of connective tissue in skin plastics are recognised enzyme preparations, for example lidaza.
The composition of hyaluronidase is an enzyme hyaluronidase, which is in the process of collagen formation in skin grafting leads to lysis of excess intercellular cementing substance of connective tissue, is necessary for reproduction of cells and collagen formation, which is accompanied by the formation of normotrophic scars (ulashchik B. C. Physico-pharmacological methods of treatment and prevention. Minsk: Belarus, 1979. - Pp. 61-63)
To prevent excessive formation and vibrationaly connective tissue in plastic surgery scarring of the eyelids perform conta�wide electrophoresis lidazy (Sosin, I. N., Buevich A. G. Physical therapy of eye diseases: a practical guide. - Simferopol: Tavria, 1998. - P. 17-22).
The disadvantages of this method are:
- the short duration of therapeutic effects due to the rapid hydrolysis of hyaluronidase, which is part of hyaluronidase, the tissue inhibitors of proteases;
- only 4-15% of the drug goes by electrophoresis in the tissue of the eyelids because of the epidermal barrier;
- possibility of destruction of healthy tissue, which impairs the engraftment of autodermotransplantat;
allergic reactions and contact dermatitis.
The closest analogue prototype is the photophoresis of Lomidze. Logidata - enzyme preparation for the treatment of diseases involving the growth of connective tissue, representing a conjugate of hyaluronidase and macromolecular polyoxidonium, immunomodulator, antioxidant and anti-inflammatory activity, are promising for therapeutic use in the connective tissue damage.
The implementation of the method is carried out from the apparatus that generates low-energy pulsed laser radiation in the infrared range with a wavelength of 0.89 microns, a pulse frequency of 1500 Hz, pulse power 4-6 W/imp. For the procedure longido ME 3000 diluted in 2 ml of distilled water and nano�it on the projection area of damaged skin, then no time interval is exposure to infrared laser radiation. Photophoresis is carried out by contact-labile method by 1-3 minute on the field, the total exposure time of up to 15 minutes, on a course - 15-20 procedures carried out daily or every other day (gagina T. A. Photophoresis of longitute in the rehabilitative treatment of localized scleroderma: author. dis. ... candidate. honey. Sciences. - M., 2011. - 22 p.).
The disadvantages of the method:
1. To create the necessary therapeutic concentrations of longitute in the skin and prolonging its physiological hinder the effectiveness of the barrier properties of the epidermis of the skin, has a low conductivity (Bogolyubov V. M. Balneology and physiotherapy. Volume 1. - M.: Medicine, 1985).
2. Due to the low bioavailability of longitute there is a high risk of poor functional (eyelid retraction, incomplete closure of the eyelids, ectropion or entropion, shortening of the palpebral fissure) and aesthetic (rough scarring, congested tissue skin graft with cyanotic edema) results blepharoplasty.
3. High incidence of secondary cicatricial deformities requiring repeated surgical intervention.
4. Due to the shortage of nucleic acid in traumatized tissue plastic and not replenished energy reserves of the cells of the connective tissue, gain his / her trust physiological processes of collagen formation.
Task - improving the anatomical and aesthetic and functional results of plastic surgery of posttraumatic deformities and defects of the eyelids.
The technical result - improving the quality of healing of the skin graft, the absence of secondary deformities of the eyelids, reducing the duration of postoperative treatment, improving the quality of life of patients.
The technical result is achieved as follows: since 7-8 days from the date of execution of blepharoplasty post-traumatic cicatricial deformity of the century, immediately after the removal of the operating joints, which corresponds to the stage of formation of the connective tissue and the regeneration of the epidermis on the area operated upon century perform the procedure consistent combined magneto-laser - magneto-photophoresis of a solution of three drugs: logidata 3000 ME, 25% solution of dimethyl sulfoxide (DMSO), 0.25% solution Derinat.
For holding the magneto-photophoresis longido ME 3000 diluted in 3 ml of 25% DMSO solution and add 1 ml of 0.25% solution Derinat. 2 ml of the prepared solution was applied by pipette to autodermal the graft to the surrounding healthy skin, receding from the edges of the wound of 1 cm, and evenly using a glass rod to distribute the solution over the surface. 3-5 minutes is applied to the entire surface of the treated skin Marle�first strip, impregnated with 2 ml of remaining manufactured solution, and the contact method for 10 minutes affect the running pulsed magnetic field apparatus "AMO-ATOS" with the pulse repetition rate of 5-10 Hz. Then, gauze pad is removed and time interval without affecting the border closure autodermal transplant and healthy skin infrared laser radiation in the range of 0.89 microns machine PATTERN-2K with a pulse repetition rate of 1500 Hz, the contact labile method by 1 minute on each field defocused beam. Magneto-photophoresis occurs daily 1 procedure within 10 days.
Components logidata - hyaluronidase and polyoxidonium - prevent excess collagen formation. DMSO has a high conveying properties and helps overcome longitute and Derinat epidermal skin barrier. Derinat is a source of nucleic acids that are involved in biosynthetic processes normally regenerating connective tissue cells.
Magnetic therapy, along with anti-inflammatory, immuno-and neuro-trophic activity, increases the flow of drugs into epidermal-dermal tissue of the eyelids. Low-frequency laser radiation enhances the process of protein synthesis from nucleic acid derived neurotrophic AK�Yunosti. The similarity of the main therapeutic effects of magnetic fields and low-frequency laser radiation contributes to their strengthening.
Advantages of the method:
1. Increased bioavailability of longitute due to the summation of the transport properties of the magnetic field, laser radiation and DMSO.
2. The use of DMSO and Derinat improves the conductivity of the epidermis, contributing to the creation of the necessary therapeutic concentrations of longitute in the skin and prolonging its physiological effectiveness.
3. Through the use of Derinat - source nucleic acid - filled plastic and energy reserves of the cells of the connective tissue.
4. Reducing the time of engraftment of the skin graft as a result of summation of the anti-inflammatory, immunomodulatory, antioxidant properties, and biosynthetic activity of physical factors and drugs used.
5. Improved functional and aesthetic results of blepharoplasty: the lack of a difference in width of the palpebral fissure and the provisions of the eyelids, ectropion or entropion of the eyelids, formation of normotrophic scars, matching patterns and colors of transplant as healthy skin, complete the eyelids.
6. Reducing the frequency of repeated plastic surgery, as it prevents the development of secondary cicatricial deformity of the eyelids because of their eversion or inversion, shortening of the palpebral fissure.
7. Reducing the total time of postoperative care.
Treated 24 patients (24 eyes) with rough scar deformity of the eyelids after blepharoplasty. With 7-8 days of the postoperative period all patients underwent physiotherapy treatment to improve the results of surgery, reduce the degree of scarring of the skin, of which 10 patients (10 eyes) - photophoresis of longitute; 14 patients (14 eyes) - magneto-photophoresis solution longdoz, DMSO and Derinat. Table 1 shows the data obtained during the observation period after surgery 1 year.
Analysis of the results showed that in the postoperative period in all 14 patients receiving physiotherapy treatment according to the proposed method - magneto-photophoresis solution longdoz, DMSO and Derinat, observed the formation normotrophic scars, the restoration of normal color and pattern of the skin.
Example 1. Patient B., 55 years old - made plastic free skin flap lower eyelid of the right eye over rough scar of inversion. When suture removal on day 7 after surgery diagnosed retraction of the skin graft, the tendency to the formation of rough premierowy above the surface of the skin scars. The patient was assigned magneto-photophoresis of longitute 3000 ME dissolved in 3 ml of 25% solution of DMSO and 1 ml of 0.25% solution Derinat, 1 p�ocedure within 10 days by the proposed method. As a result of treatment postoperative scar and skin graft became more soft, elastic, structure and color of skin graft closer to the normal adjacent healthy tissue. Saved the correct position of the lower eyelid in the operated eye, the border closure between the graft with the wound bed even without the color change. After 1 year of follow-up was marked complete the eyelids, the difference in width of the palpebral fissure and the position of the eyelid was absent.
Example 2. Patient G., age 38 - was held Ζ-plastic post-traumatic scars with an additional transplantation of free skin flap upper eyelid local fabrics by reason of the retraction of the upper eyelid with the formation of lagophthalmos to 3 mm. Before entering surgery twice was operated in a residence, but the operation ended with the formation of a rough strain of transplant and age. On the 7th day of the postoperative period after removal of sutures assigned by the proposed method magneto-photophoresis of longitute 3000 ME dissolved in 3 ml of 25% solution of DMSO and 1 ml of 0.25% solution Derinat. After 10 sessions, magneto-photophoresis was complete engraftment with restoring proper position and form of the century, with good functional activity, with the formation of a Mature scar in color, PR�approximate to the healthy skin. After 6 months: the eyelids and restored functional activity; the difference in width of the palpebral fissure compared with the healthy eye is missing; structure and color took hold of transplant correspond to healthy skin; secondary cicatricial deformity of the upper eyelid was observed.
|Comparative characteristics of the results obtained 1 year after pharmacopolitics treatment|
|The results of plastic surgeries||The surveyed group (absolute number of patients)|
|Photophoresis of longitute,|
|Magneto-photophoresis of longitute, DMSO and Derinat, n=14|
|The presence of scars:|
|The difference in width of the palpebral fissure compared with the healthy eye:|
|Secondary cicatricial deformity of the eyelids (ectropion, entropion century, shortening of the palpebral fissure):|
A method for improving functional-aesthetic plastic surgery of posttraumatic deformities of the eyelids, consisting of pharmacopolitics introduction to tissue-century longdoz, characterized in that, starting from 7-8 days from the date of execution of blepharoplasty post-traumatic cicatricial deformity of the century, immediately after the removal of the operating joints, the area operated upon century perform the procedure magneto-photophoresis of a medicinal solution, izgotovleno� from 3000 ME of longitute, 3 ml of 25% solution of dimethyl sulfoxide and 1 ml of 0.25% solution Derinat, 2 ml of the prepared solution was applied to autodermal the graft to the surrounding healthy skin, receding from the edges of the wound 1 cm, 3 to 5 minutes is applied to the treated surface of the skin with a gauze pad soaked in 2 ml of remaining manufactured solution, and the contact method for 10 minutes affect the running pulsed magnetic field apparatus "AMO-ATOS" with the pulse repetition rate of 5-10 Hz, and then removing the strip, without a time interval, handle the border closure autodermal transplant and healthy skin infrared laser radiation in the range of 0.89 microns machine PATTERN-2K with a pulse repetition rate of 1500 Hz, the contact labile method by 1 minute on each field by performing daily 1 procedure within 10 days.
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to cosmetology, namely represents a composition containing minoxidil and/or minoxidil sulphate combined with additives containing at least one antioxidant, at least one organic acid and selected fatty acids mixture. Besides, the invention refers to using the compounds for hair growth enhancement/recovery and/or hair loss prevention in mammals, particularly in a human.
EFFECT: using the invention provides faster anagen phase in mammalian hair growth and/or enhanced terminal hair above the skin surface by local application the declared compositions.
19 cl, 9 tbl
FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to medicine, namely to dermatology, and can be used for preventing and/or treating skin itching. It involves using L-serine as a therapeutic agent, a pharmaceutical composition containing L-serine, as well as a dermato-cosmetic composition containing L-serine as a single active agent, Avene Thermal Spring Water, glycerine and a cosmetically acceptable carrier. The L-serine concentration in the composition makes from 0.01 wt % to 10 wt % in relation to the total weight of the composition. More preferentially, the concentration makes 0.5 wt % to 3 wt % in relation to the total weight of the composition.
EFFECT: group of inventions provides the effectiveness of application.
8 cl, 2 tbl, 3 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions relates to medicine, namely to dermatology and mycology, and can be applied in the treatment of skin and its appendages. A pharmaceutical composition for external application contains nanoparticles for the laser thermotherapy of infectious affections of the skin and its appendages. The nanoparticles are characterised by, at least, one localised surface Plasmon resonance in the range of a wavelength from 400 to 1100 nm. The nanoparticles are dispersed in a physiologically acceptable carrier, which is characterised by the absence of the absorption or weak absorption and/or weak dispersion of light radiation in the said range of wavelengths and possessing biocidal properties. The pharmaceutical composition is applied on an affected area and irradiated by laser radiation with a wavelength close to the wavelength of the localised surface Plasmon resonance of the nanoparticles, contained in the composition, or equal to it. The irradiation is continued until the desirable temperature of heating of the said area is achieved.
EFFECT: group of inventions ensures an increased treatment efficiency, reduction of a risk of development of side effects, reduction of the number of recurrences due to the application of the pharmaceutical composition, capable of absorbing energy of the light radiation and transforming it into heat energy with the achievement of the specified temperature with laser irradiation at the specified wavelength with the lower intensity of laser radiation and possessing biocidal properties.
63 cl, 3 dwg, 1 tbl, 4 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to the pharmaceutical industry and represents a pharmaceutical composition for the external application for the treatment of skin diseases in the form of a cream, which includes as an active substance methylprednisolone aceponate in a therapeutically effective amount and a lipophilic base, characterised by the fact that as the lipophilic base it contains petrolatum, liquid paraffin and oil of castor oil plant seeds and additionally white bee wax, with the components of the composition being in a specified ratio in g/100 g of the composition.
EFFECT: invention provides the creation of the stable composition, improved pharmacological properties and absence of an irritating effect.
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutical industry and represents an anti-allergic agent containing polysaccharide containing galactose, glucose and rhamnose as ingredients, wherein polysaccharide contains galactose, glucose and rhamnose in molar ratio 3-5:1-3:1, and polysaccharide has certain structure.
EFFECT: invention provides extending the range of antiallergic agents.
12 cl, 6 ex, 6 dwg, 1 tbl
FIELD: medicine, pharmaceutics.
SUBSTANCE: pharmaceutical composition in the form of a tablet with an erodible matrix, which contains one or more fumaric acid ethers, as well as a rate-controlling agent, representing hydroxypropylcellulose and a binding agent, representing lactose, with the decomposition of the said degradable matrix providing the controlled release of the said fumaric acid ether (ethers).
EFFECT: provision of the controlled release of fumaric acid ether (ethers).
19 cl, 43 ex, 2 tbl, 2 dwg
SUBSTANCE: invention relates to the beauty industry, representing a gel-like composition for topical application, containing salicylic acid with the concentration of ca. 17 wt %, elastic collodion in the amount of 5 to 10 wt % and ethyl lactate in the amount of 20 to 25 wt %, where the elastic collodion contains 65.8 wt % diethyl ether, 24.3 wt % ethanol, 2 wt % camphor, 3 wt % castor oil and 4.9 wt % nitro-cellulose.
EFFECT: invention provides excellent stability, even drying and the formation of a uniform film.
5 cl, 1 tbl, 4 dwg
SUBSTANCE: melanin having water-solubility of at least 80% and an paramagnetic centre concentration of at least 8·1017 spin/g is administered orally into the animals having been exposed to the radiation in a dose high enough to cause a spinal radiation injury; melanin is administered after dissolved in distilled water in the effective concentration. Melanin water is used as drinking water for the mice having been exposed to single and fractionated acute radiation, which is able to cause acute radiation disease. Melanin water is taken from the 1st to 30th day following the single radiation, or from the 1st day of the fractionated radiation to the 30th day on completion of the radiation.
EFFECT: higher survival rate, faster recovered haemopoiesis, body weight and orientation and motion activity.
7 tbl, 5 ex
SUBSTANCE: invention refers to medicine, more specifically to clinical dentistry. The invention represents a composition for treating erosive ulcerative and exudative hyperaemic forms of oral lichen planus.
EFFECT: implementing the invention provides high oral adhesion of the preparation, increases the therapeutic concentration of the preparation in the area of involvement (inflammation), accelerates the length of treatment (reduces the size of erosion, the length of epithelisation of erosions).
SUBSTANCE: pharmaceutical composition possessing a therapeutic action on various skin pathologies contains triptantrin, chitosan and distilled water, a lanoline and Vaseline mixture and protein-nucleic hydrolyzate of the salmonid fishes milt in a certain mixture ratio.
EFFECT: composition enables increasing the clinical effectiveness in the skin pathologies of various origins and extending the range of pharmaceutical compositions having the therapeutic effect on the various skin pathologies.
3 tbl, 4 dwg, 7 ex
SUBSTANCE: what is involved is a single slow drop infusion of cisplatin 0.5 ml in the concentration of 0.5 mg/ml into a subcapsular space of a tumour. That is combined with the exposure to a scanning magnetic field (SMF) in the frequency range of 1 Hz to 150 Hz, an induction of 20 mT, an exposure of 10 minutes in a combination with a permanent magnetic field of 20 mT generated by an inducer arranged in the centre between poles of the scanning field.
EFFECT: higher cytostatic permeability, enhanced anticancer effect; the method is cost-efficient, accessible by cheap domestic magnetic therapeutic instruments.
1 tbl, 1 dwg
SUBSTANCE: for complex therapy of the first time identified pulmonary tuberculosis traditional anti-tuberculosis therapy is carried out. After two weeks of anti-tuberculosis chemotherapy, complex physiotherapy is performed. In the morning 40-60 minutes after meal ultrasound inhalation with an inhibitor of proteases contrykal in a dose of 5000 UNITS, diluted in 3-4 ml of an isotonic solution of sodium chloride is carried out. Inhalation is carried out at a temperature of the solution of 35°C for 10 minutes on the apparatus "Vulkan-1". 20 minutes after inhalation magnetic infrared laser therapy (MIL-therapy) is performed from the apparatus "Rikta-04/4" on affected zones of the lungs by contact method of the application of the apparatus emitter. Frequency of the laser impact constitutes 5-50 Hz. Average power of infrared light-diode radiation is 60±30 mW, an impact with constant magnetic field is realised with induction 35±10 mT for 1-5 min. The course of treatment constitutes 30-40 daily procedures as well.
EFFECT: enhancement of infiltration resorption, closing decay cavities in the shorter period, arrest of intoxication symptoms by the end of the first month of treatment, reduction of terms of elimination of clinical and laboratory manifestations of tuberculosis.
3 cl, 2 ex
SUBSTANCE: invention refers to medical equipment, namely to drug delivery control units using a magnetic body. The magnetic body comprises a magnet and a coating element attached to an end surface of the magnet. The coating element consists of a material with high magnetic permeability; a length-to-radius ratio of the coating element makes 10:1 to 7:3; the side surface of the coating element is longitudinally tapered, and the upper end of the tapered side surface of the coating element is spherical. The drug delivery control unit comprises the magnetic body, a supporting head for the magnetic body and a head drive mechanism which actuates the head along the projected portion formed by the injured region in relation to the tissues surface.
EFFECT: using the invention enables more effective and adjustable drug delivery.
6 cl, 14 dwg
SUBSTANCE: invention refers to medicine, namely to magnetic therapy, and may be used to treat various diseases by the magnetic field exposure generated by a permanent magnet placed outside the body. A magnetic applicator comprises a flexible plate made of a high-permeability elastomer on the basis of a polymer binding and an excipient - a high-permeability powder, whereon there is the flexible plate made of a hard-magnetic elastomer on the basis of the polymer binding and the excipient - a hard-magnetic powder and magnetically charged in the direction perpendicular to the plate plane with alternating magnetic poles. The declared applicator on the basis of the double-layer elastomer generates the magnetic field being an order of magnitude greater than that in known analogues.
EFFECT: applicator is able to increase the 'length' of the magnetic field by 5-10 times as compared to the existing ones with the standard elastomer thickness (no more than 3 mm), and thereby to magnetise the adjoining parts of body by a depth 5 times greater, and thereby to intensify substantially a magnetotherapeutic effect of using the same.
3 cl, 3 dwg, 1 tbl
SUBSTANCE: invention refers to medicine, namely otolaryngology, and may be used for treating acute-on-chronic rhinosinusitis. For this purpose, iron-containing ferrihydride nanoparticles prepared by the culture of the bacteria Klebsiella oxytoca recovered from sapropel of Borovoye Lake of the Krasnoyarsk Territory, mixed with a water-dissolved antibiotic, applied on the nasal mucosa and exposed to a magnetic field for 20 minutes.
EFFECT: method enables providing the higher clinical effectiveness ensured by the targeted antibiotic delivery into the tissues with the intensive and prolonged therapeutic action thereof.
2 cl, 2 dwg, 1 ex
SUBSTANCE: invention refers to medicine, namely to - physiotherapy. A method involves drug administration and exposure to sine waveform electromagnetic field of carrier frequency within the range 100 - 1000 Hz with amplitude-modulated low-frequency signal. The exposure covers a trunk by means of a first element placed under a patient's back, while a head is exposed simultaneously by means of a second element placed thereon. The exposure represents amplitude-modulated low-frequency signal of constantly varying frequency within the range 20 - 8000 Hz, electric field intensity at an emitter surface 0.5 - 1.0 V/m. Additionally, the patient's head is treated with a third element. An element containing a light-emitting unit is placed above the patient's head. It emits quasi-monochromatic pulse visible and short-range IR radiation of wave length of IR spectrum 880 nm and red spectrum 640 nm and frequency 100 Hz. Exposure power is 2 mWt/cm2. Exposure area is 10 cm2. Duration of a procedure is 15-20 minutes. The procedures are daily. Therapeutic course is 10-15 procedures.
EFFECT: way reduces length of postoperative treatment in the patients with a craniocerebral injury due to integrated exposure of electromagnetic fields.
SUBSTANCE: invention refers to medicine, namely - to oncology, physiotherapy. A method involves surgical treatment and electromagnetic radiation exposure. It is added with preoperative exposure. Herewith, the exposure covers the whole body, except a nidus. The postoperative exposure covers the whole body. The exposure represents high-frequency electromagnetic field of sine waveform and carrier frequencies within 100-500 kHz which are amplitude-modulated with a low-frequency signal of constantly varying frequency within frequency range 10-10000 Hz and amplitude. The exposure is performed with a system of local flat exposure apparatuses. Each apparatus comprises an emitter representing an inductance coil with its coil block placed on a flat dielectric frame and is a component of an LC tank. A first half of the local apparatus is placed under a patient. A second half is above the patient. A head is exposed to an apparatus comprising the emitter representing the inductance coil with its coil block placed on the cylindrical frame. Electric field intensity at a surface of each emitter makes 0.5-1.0 V/m. The procedures are daily for 20-30 minutes. The surgery is preceded with 3-5 procedures. And 10-15 postoperative procedures follows.
EFFECT: method reduces treatment length due to enhanced postoperative repair processes in the postoperative period and higher immune status.
SUBSTANCE: invention refers to medicine, namely - to restorative and sports medicine. The method involves exposure to magnetic infrared laser radiation. Laser exposure is synchronised with a sportsman's chronotype and combined with the oral administration of phyto-cocktail. The phyto-cocktail consists of 70% alcoholic tinctures of elfwort, common licorice, spiny eleuterococcus, Manchurian aralia taken in the ratio 2:2:1:1. The exposure to magnetic infrared laser radiation covers acupuncture points through applicators saturated with said phyto-cocktail. The exposure is combined with sessions of lavender essence aromatherapy and music therapy.
EFFECT: method improves adaptative recourses of a sportsman's body, enhanced its general and physical performance due to optimising vegetative balance, normalising disordered time arrangement of the primary cardiovascular indices, and decreasing anxiety level.
2 ex, 3 tbl, 4 dwg
SUBSTANCE: invention concerns medicine, oncology, and can be used for selective destruction of tumours. For this purpose, a photosensitiser is encapsulated in polymeric microcontainers enclosed in shells that contain magnetite (Fe3O4) nanoparticles, and introduced in the surrounding biological tissue. The external constant magnetic field with its spatial configuration matched with the tumour shape is generated in the tumour bulk. Laser exposure follows within a given period corresponding to maximum accumulation of the microcontainers in the tumour at radiant energy density sufficient for photodynamic or photothermal destruction of the microcontainers shells in the tumour and following photodynamic or photothermal destruction of malignant cells. The photosensitiser is specified with an absorption band chosen with an absorption strip in red and close IR-spectral region 650-1200 nm.
EFFECT: method allows more effective destruction of cancer cells ensured by higher degree of photosensitiser accumulation in the tumour with minimal destruction of the surrounding healthy cells and a surgical procedure without general anaesthesia.
4 cl, 9 dwg
SUBSTANCE: invention relates to medicine, namely to physiotherapy in obstetrics and can be used for treatment of anemia in pregnant women. For this purpose, traditional pharmacotherapy with iron-medications is carried out. Additionally, projection of cubital vein is exposed to magnetic field in combination with laser irradiation with power 60 mW, frequency 150 Hz. Exposure is performed daily, 20 minutes per session, course consists of 10 procedures.
EFFECT: method allows to reduce considerably possibility of developing complications during pregnancy due to possibility of anemia correction at early terms of pregnancy.
3 dwg, 1 ex
SUBSTANCE: what is involved is an integrated pathogenetic therapy containing detralex 3 tablets two times a day (a daily dose of diosmin 2,700 mg, hesperidin 300 mg) for 4 days, then 2 tablets two times a day (a daily dose of diosmin 1,800 mg, hesperidin 200 mg) for 9 days, Trombovazim 1 tablet (800 units) 2 times a day for 15 days as a basic course, then 1 tablet (800 units) 1 time a day) 15 days as a supporting course, and a preparation of thioctic acid 600 mg intravenously in normal saline 200.0 drop-by-drop at max. 60 drops/min for 13 days, then 600 mg a day in the form of tablets for 17 days.
EFFECT: effective reduction of reperfusion syndrome in the given category of patients by increasing venous vascular tone, improving rheological blood properties and trophism of injured nerve terminals.
2 cl, 10 dwg, 9 tbl, 3 ex