Method for early postoperative management of patients with dental implants

FIELD: medicine.

SUBSTANCE: 20-25 minutes after surgical intervention, a mouth bath of an implantation area with the Tonsinal phytopreparation diluted in an amount of 2.5 g in 100 ml of boiled water of room temperature is executed. 20-25 minutes later the Plastin CM-1 phytopreparation is applied on the alveolar process mucosa within the implantation area from the vestibular side for 1.5-2 hours. That is preceded by the desalivation of the oral cavity and mouth rinsing carefully with the Tonsinal solution trying to avoid any dynamic movements. The above procedures are performed 3-4 times a day for at least 10 days.

EFFECT: more effective dental implantation by improving microcirculation, fast normalising of oral microbiocoenosis, wound surface healing by immediate union, reliable implant attachment to gums and providing the implant stability.

3 ex

 

The invention relates to medicine, in particular to dentistry, and can be used for dental implantation.

Dental implantation is currently one of the urgent tasks of modern dentistry. The use of dental implants allows to solve many problems, including the restoration of masticatory function by partial or complete loss of teeth, improve facial aesthetics. Experience placing dental implants continues to accumulate in all its aspects, taking into account the functional state of the organism, its features, it is possible to achieve a good result (Robustova T. G. Implantation (surgical aspects). A guide for physicians. M.: Medicine, 2003, 560 p.).

The stability of both the operational and post-operative periods of dental implantation has important functional and aesthetic role. But the scheme of medical support used in this type of interventions do not always lead to a favourable result of the operation and a smooth postoperative period (Bondarenko I. V. Modern approaches to immunoprophylaxis and immunotherapy in operations on the face and dental implantology. Russian dental journal., 2005, No. 3, Pp. 35-40). According to the carried out works and studies by various authors, with the purpose of prevention of�of legnani in the process of dental implantation were applied magnetic-laser therapy, darsonvalization, structural-resonance therapy, ozone therapy, various antiseptics and medicines, magnetobacteria therapy, photophoresis of helical, ozone therapy and homeopathic medicines. Moreover, one of the main circuits of the medicinal support of the process of surgery in dental implantology is the use of antibioticsbacterial drugs that are appointed without any system (Ashraf E. AbuKaraky et al. Antibiotics prescribing practices in oral implantology among Jordanian dentists. A cross sectional, observational study. BMC Research Notes 2011, 4:266). This source of information is accepted by us for the closest analogue. However, all this is not always effective enough and often has a negative impact on the immune status of the organism (Renton, K. W. Cytochrome P450 regulation and drug biotransformation during inflammation and infection. Curr. Drug. Metab., 2004, V. 5, No. 3, P. 235-243). In the background of medication in the mouth develop stomatitis, gingivitis, glossily, aphthae, erosions, etc. (barer G. M. preventive dentistry: textbook, part 2. Periodontal disease, M.: GEOTAR-Media, 2008, 224 p.). Also of note is the increase in the sensitization of the population and development of perioperative anaphylactic reactions (American College of Allergy, Asthma and immunology (ACAAI) Annual Scientific Meeting, 2013, Abstract 1 presented November 10, 2013). All this requires new approaches to carrying out dental implantation. Today, one of the same� methods can be modern phytotherapy. There is growing interest in the use of herbal preparations have on the body soft and at the same time, the effective action. Natural substances of herbal remedies in most do not show allergic properties, biogenetically closer to the human body, reacting with the enzymes, it is easy to be involved in the processes of tissue metabolism. Vegetable substances have active and directed action. Therapeutic effect of herbal remedies for high and stable, while the negative side effects when used correctly is not seen. Herbal drugs have done well in dentistry were obtained reliable results positive effect of their use in the complex treatment of gingivitis, periodontitis in different groups of patients (E. A. Gorbatov, Lamarca T. N., B. M. Manuilov Domestic drugs from plant material in the complex treatment of periodontal diseases. Dentistry for all., 2000, No. 4, pp. 35-38).

First we assessed the efficacy of drugs of herbal medicine in the process of dental implantation, particularly in the early postoperative period, and the algorithm of their appointment.

The technical result of the claimed method is to increase the effectiveness of dental implant�tion by improving microcirculation in the early postoperative period, rapid normalization of microbiocenosis the oral cavity, the wound heals by primary intention, reliable implanto-gingival attachment and stabilization stability of the implant, and reduce the time of surgical and phytotherapeutic treatment.

The technical result is achieved in that in the early postoperative period, dental implantation, immediately after the surgery for 20-25 minutes perform oral bath of the implantation zone of the phytopreparation "Tonsina" dissolved in an amount of 2.5 g in 100 ml of boiled water at room temperature, 20-25 minutes after that, in the implantation area on the mucous membrane of alveolar process from the vestibular side impose drug "Plate CM-1 in the 1.5-2 hours, previously before this remove saliva from the mouth and rinse the mouth with a solution of Continua" with caution without vigorous movements, these procedures are 3-4 times a day for at least 10 days.

The method is as follows.

Before dental implantation is carried out to assess the overall health status of the patient, which mainly consists of anamnesis, results of blood tests and urine and necessarily is based on the opinion of the district physician or family doctor. In some�which cases the necessary consultations with specialists, and provision of additional methods of research.

Also carry out a dental examination of the condition of the oral cavity, which consists in the study of dental history taking; clinical assessment of the condition of the teeth, dentition, temporomandibular joint, mucosa of the oral cavity, the relationship of the jaws (bite); study of diagnostic models; x-ray examination of the teeth-jaw system. Before implantation it is necessary to obtain a panoramic image of the jaw with the use of plastic or wax patterns attached to them radiopaque pins or balls of standard size. Such features are associated with the need to measure the distance from the top of the alveolar crest to the mandibular canal, maxillary sinuses and other anatomical structures. In some cases, the required sighting intraoral images; measurement of the thickness of the mucosa at the surgical site and determining the width of the alveolar portion of the jaw. In addition, if necessary, conduct a CT scan of the jaws; the conduct of bipotentiality tissues of the oral cavity, especially during implantation with the use of dissimilar metals.

As additional methods used gnato the dynamometry, electromyography, dopplerflowmetry, etc. After which the patient performed one of the necessary dental�tion implantation, in particular either endodont-indossano implantation. This implantation is carried out while moving or severely damaged teeth by insertion through the root of the tooth to the underlying bone screw or with shaped implant surface in the form of a pin. Either indossano implantation. In this case, the fixation of the implant is carried out through integration into the bone tissue of the "root" part of the implant. Or intraosseous implantation, which is the most common effective type of implantation. Any intraosseous implant consists of intraosseous (root) part of the neck (which adjoins the mucous membrane of the gums) and superstructure (head protruding into the cavity). Most often this detail is called the abutment. The implants can be collapsible, i.e., screw-retained crown to the root. Or subperiosteal implants. In this case, subperiosteal implants are metal frame with exposed into the oral cavity supports, are made based on an impression of the jaw bone and placed under the periosteum. Subperiosteal implantation is typically used when it is impossible to hold intraosseous implantation due to insufficient height of the alveolar part of the jaw. Or vnutrikitayskoy implantation. These implants are a fungus�prominent protrusions on the inner part of the basis of complete dentures, included in its imposition in corresponding recesses in the mucosa. These recesses are formed by surgery. Or subclinical implantation, involving the introduction under the mucous membrane of the transition folds of the oral cavity of the magnet and a corresponding location in the denture base magnet of the opposite pole. Either perosseous implantation. Such implants are used when there is a sudden atrophy of the lower jaw; their intraosseous portion passes through the thickness of the jaw in segmentalism Department and secured at the basal edge of the jaw. After prosthetic treatment of the patient takes oral bath postoperative zone phytopreparation "Tonsina" dissolved in an amount of 2.5 g in 100 ml of boiled water at room temperature (18-25°C) for 20-25 minutes. Thus the solution is not to chase vigorously on the mouth and just hold it, and then spit and repeat again, and so for twenty to twenty five minutes. Vigorous movements can cause the wound may start to bleed or contained opportunistic microbes (under certain conditions can become pathogenic) in the oral cavity will be introduced into the hole tooth extraction, causing the inflammatory process. Therefore, to get the desired effect, you should do not rinse and do the tub of the operating zone. Then through 2-25 minutes after oral baths on the mucous membrane of alveolar process from the vestibular side of the upper or lower jaw, depending on the localization of an intervention, impose "Plate CM-1 in the 1.5-2 hours pre-before applying, remove the saliva and gently without vigorous movements rinsed the oral cavity with phytopreparation "Tonsina". Plate are pressed with light massage movements until complete adhesion to the gums. Data manipulation is repeated 3-4 times a day for at least 10 days. This algorithm purpose herbal remedies "Tonsina" and "Plates CM-1 in the early postoperative period provides high efficiency of dental implantation by improving microcirculation in the early postoperative period, rapid normalization of microbiocenosis of the mouth, the healing of the wound surface by primary intention and reliable implanto-gingival attachment and stabilization stability of the implant. In addition, a good wound healing effect generally improves the health of the patient.

At the Department of maxillofacial surgery in dental faculty MSMSU. A. I. Evdokimov studies have been conducted on the use of herbal remedies - "Continua and Plates, CM-1" in 10 patients of different age groups (from 27 to 65 years), without the presence of concomitant pathologies and lesions odontogenic infection was carried out dental implantation for full or frequent�ment of the absence of teeth on the upper or lower jaw. Immediately postoperatively, patients were administered the herbal remedies on the proposed scheme: "Tonsina", in the form of powder, 2.5 g of which was dissolved in 100 ml of boiled water at room temperature. The resulting solution was applied to the mouth baths 3-4 times a day for 20-25 minutes. Further, after oral baths on the mucous membrane of alveolar process from the vestibular side of the upper or lower jaw, depending on the localization of an intervention, imposed a "Plate CM-1 in the 1.5-2 hours. Prior to the imposition of "Plate CM-1" remove saliva from the mouth and rinse (no vigorous movements) her "Continuom". These therapeutic manipulations were performed 3-4 times per day. The course of treatment was not less than 10 days.

Examination of patients was performed at 3 days and 10 days. Suture removal was also carried out for 10 day. Investigated the microcirculation in the early postoperative period, microbiocides mouth, implanto-gingival attachment and stability of the implant in the process of ongoing treatment.

All patients reported a positive trend in relation to reliable implanto-gingival attachment and stabilization stability of the implant, the healing of the surgical area was the primary tension, without dehiscence and signs of inflammation None of the patients in this group are not noted inconveniences when using drugs. Pain in the early postoperative period was stopped by analgesics.

Ten patients of different age categories, without the presence of concomitant pathologies and lesions of odontogenic infection from dental implants to full or partial absence of teeth, which were prescribed antibiotic therapy, were studied in the postoperative period on the microcirculation in the early postoperative period, microbiocenosis mouth, implanto-gingival attachment and stability of the implant in the treatment process.

Positive dynamics was noted in 6 patients. In 3 developed gingivitis, which required the appointment of additional anti-inflammatory treatments. The healing of the surgical area they had for a longer period, which negatively affected implanto-gingival attachment and implant stability. The 1st patient on the background of antibiotics the wound swollen for 3 days, there was redness, pain, increased local temperature, the wound bed was covered with a sero-purulent discharge, which resulted in a wound healing by secondary intention and negatively impacted implanto-gingival attachment and stability of the implant.

The success of using the above scheme of the claimed method of management of patients with dental and�plantati in the early postoperative period was determined by the use of mouth trays from phytopreparation "Continua" (2.5 g powder dissolved in 100 ml of boiled water at room temperature) for 20-25 minutes was the optimal time for enabling the normalization of microcirculation in the wound surface, on the 10th day after lowering the level of blood flow was only 7%, and the activity of 3% and decrease of amplitude-frequency characteristics of 5-8%. The use of "Plates CM-1" immediately after the mouth baths helped to increase the duration of action of herbal drug "Continua" and the effectiveness of the integrated effects of Continua" and "Plates CM-1 in the microcirculation, microbiocides and wound healing by primary intention, as well as the reliability of the attachment of the implant and its stability, which was registered in 99, 5% of cases, against 60% in the traditional scheme (antibiotic) management of patients with dental implants in the early postoperative period.

Thus, the conducted research and the results obtained allow to increase the efficiency of dental implantation using the inventive method of management of patients with dental implants in the early postoperative period, as well as reduce the time of surgical and phytotherapeutic treatment.

Clinical examples of the method

Example 1

Patient S., 74 years old, asked the clinic with complaints of poor fit of the denture on the lower jaw, difficulty chewing food.

The patient clinically and radiographically examined.

Diagnosis: Complete absence of teeth on the mandible.

Given the pronounced atrophy of the alveolar process in the mandible, recommended the installation of two dental implants in the lower jaw for the purpose of fixation of the denture on the spherical attachments.

Under local anesthesia established two implants on the lower jaw. Immediately after the surgery the patient received oral bath this zone phyto drug Tonsina" dissolved in an amount of 2.5 g in 100 ml of boiled water at room temperature for 20 minutes. Then after oral baths from the oral cavity removed the saliva and gently rinsed "Continuom", and on the mucous membrane of alveolar process from the vestibular side of the lower jaw in the area of suture line put "Plate CM-1 at 1.5 hours. These procedures were repeated 3 times a day. In addition, the patient in pain applied Pentalgin 1 tablet 3 times a day.

The patient was not prescribed any antibiotics or antiseptics local action. The course of treatment was 10 days.

Inspection �aziende was carried out on 3rd and 10 days in the postoperative period.

On the 3rd day: complaints of moderate pain in the recovery area; the configuration of the face is not changed (there is a post-operative edema); in the mouth: the seams are wealthy, the wound in the epithelialization phase, the mucosa, corresponding to the operating wound, slightly hyperemic.

10 days: no complaints; the configuration of the face is not changed; in the mouth: the seams are wealthy, times healed by primary intention without signs of inflammation produced by the removal of stitches, the implant is securely attached and stable. Thus, the proposed scheme of reference of the patient in the early postoperative period, and the algorithm used to assign herbal remedies "Continua and Plates, CM-1 provided good circulation, rapid normalization of microbiocenosis the oral cavity, wound healing by primary intention and reliable attaching and stabilizing the stability of the implant.

Example 2

Patient I., aged 28, was admitted with complaints of absence of teeth 3.6, 4.6, difficulty chewing food. According to the patient, the teeth 3.6, 4.6 deleted about 2 years ago.

The patient clinically and radiographically examined.

Diagnosis: Partial secondary absence of teeth on the mandible.

Recommended installation of dental implants in the mandible in the area of missing teeth 3.6 and 4.6 of the agreement.

Under local anesthesia produced at�climate of two dental implants in the field of 3.6, 4.6 the teeth.

Immediately after the surgery, the patient had a mouth tray that zone the phytopreparation "Tonsina" dissolved in an amount of 2.5 g. in 100 ml of boiled water at room temperature for 25 minutes. Then after oral baths from the oral cavity removed the saliva and gently rinsed her "Continuom", and on the mucous membrane of alveolar process from the vestibular side of the lower jaw in the area of suture line put "Plate CM-1 in 2 hours. These procedures were repeated 4 times a day. In addition, the patient in pain applied Pentalgin 1 tablet 3 times a day.

The patient was not prescribed any antibiotics or antiseptics local action.

The course of treatment was 12 days.

An examination was made on the 3rd and 12th day after the operation.

On the 3rd day: complaints of moderate pain in the recovery area; the configuration of the face is not changed (there is a post-operative edema); in the mouth: the wound in the epithelialization phase with signs of inflammation.

12 days: no complaints; the configuration of the face is not changed; in the mouth: the seams are wealthy, times healed by primary intention without signs of inflammation; produced suture removal, the implant is securely attached and stable. Thus, the proposed scheme of reference of the patient in the early p�lesoperational period, the algorithm for assignment of herbal remedies "Tonsina and Plates, CM-1 provided good circulation, rapid normalization of microbiocenosis the oral cavity, wound healing by primary intention, reliable attachment and stabilization of the stability of the implant.

Example 3

Patient G., age 31, was admitted with complaints of the lack of tooth 3.6, difficulty chewing food. According to the patient's tooth 3.6 deleted about 2 years ago. The patient is examined clinically and radiographically.

Diagnosis: Partial secondary absence of teeth on the lower jaw. Recommended inserting the dental implant into the missing tooth 3.6.

Under local anesthesia produced by inserting the dental implant at tooth 3.6.

Immediately after the surgery the patient received oral bath in this zone the phytopreparation "Tonsina" dissolved in an amount of 2.5 g in 100 ml of boiled water at room temperature over a period of 23 minutes. Then after oral baths on the mucous membrane of alveolar process from the vestibular side of the lower jaw in the area of suture line packing Plate CM-1 in 2 hours. Prior to the imposition of "Plate CM-1 from the oral cavity removed the spit and rinsed "Continuom". These procedures were repeated 3 times a day.

The patient was not prescribed any antibacteria� - to-date drugs, neither antiseptics local action.

The course of treatment was 10 days.

Examination of the patient was performed on the 3rd and 10th day of the postoperative period.

For 3 days: no complaints, pain killers does not accept; the configuration of the face is not changed (there is a post-operative edema); in the mouth: the wound in the epithelialization phase, but with signs of inflammation.

10 days: no complaints; the configuration of the face is not changed; in the mouth: the seams are wealthy, the wound healed by primary intention; produced suture removal, the implant is securely attached and stable. The proposed scheme of reference of the patient in the early postoperative period, and the algorithm used to assign herbal remedies "Continua and Plates, CM-1 provided good circulation, rapid normalization of microbiocenosis the oral cavity, wound healing by primary intention, reliable attachment and stabilization of the stability of the implant.

Thus, using the above scheme the purpose of herbal remedies "Continua" and "Plates CM-1 in patients with dental implants in the early postoperative period, provided the normalization of the microcirculation of the wound surface, microbiocenosis the oral cavity, wound healing by primary intention and reliable attaching and stabilizing the stability of the implant. It has improved the overall health of patients has significantly increased and their quality of life.

Method of managing patients with dental implants in the early postoperative period, characterized in that immediately after the surgery for 20-25 minutes perform oral bath of the implantation zone of the phytopreparation "Tonsina" dissolved in an amount of 2.5 g in 100 ml of boiled water at room temperature, 20-25 minutes after that, in the implantation area on the mucous membrane of alveolar process from the vestibular side impose drug "Plate CM-1 in the 1.5-2 hours, previously before this remove saliva from the mouth and rinse the mouth with a solution of Continua" with caution without vigorous movements, these procedures are 3-4 times a day for at least 10 days.



 

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7 cl, 4 dwg, 5 ex

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to the chemical-pharmaceutical industry and represents an agent for preventing or reducing pigmentation, containing a compound presented by the following formula (1) its stereoisomer and/or its pharmacologically acceptable salt, wherein: R1 represents a hydrogen atom or an alkyl group with a linear or branched chain having 1-4 carbon atoms; R2 represents a hydrogen atom or an unsubstituted aliphatic hydrocarbon group having 1-4 carbon atoms; R3 represents an unsubstituted aromatic group having 5-15 carbon atoms, substituted by an alkyl group having 1-6 carbon atoms, by an alkoxy group containing an alkyl chain having 1-6 carbon atoms, or by a phenyl group; R3 also represents an aromatic group having 5-15 carbon atoms; n is equal to 1 or 2, and m represents an integer falling within 0 to 3.

EFFECT: preparing the agent for preventing or reducing pigmentation.

10 cl, 10 ex, 6 tbl

Hair care product // 2553347

FIELD: cosmetology.

SUBSTANCE: hair care product is made in the form of gel, shampoo, lotion. All embodiments comprise aqueous vegetable extracts, phosphonate complex containing potassium-sodium salts of oxyethylidenebisphosphonic acid or their mixture with trisodium salt hexahydrate of phosphonformic acid and a cosmetically acceptable base.

EFFECT: hair care product is recommended for use in medicinal and cosmetic purposes for all ages for prevention and treatment of dystrophic changes in hairy part of the head.

5 cl

FIELD: cosmetology.

SUBSTANCE: cosmetic product contains an aqueous solution of trace elements in amounts close to the daily demand of the human body, succinic acid which provides a high level of energy production (ATP), and also a bioregulatory complex obtained from hair follicles of calves, which stimulates proliferation of dormant cells of hair follicles.

EFFECT: increased efficiency of cosmetic product for complete prevention of hair loss caused by a wider range of reasons, and for partial or complete restoration of hair.

5 ex

FIELD: chemistry.

SUBSTANCE: invention relates to application of dry extract of aronia melanocarpa as hypolipidemic agent. Claimed extract is obtained by double extraction with 95% ethanol, acidified with hydrochloric acid, at heating on water bath.

EFFECT: claimed invention ensures obtaining agent with expressed ability to reduce level of triacylglycerols, total cholesterol and cholesterol in atherogenic lipoproteins of low density in blood serum.

3 tbl, 3 ex

Dental implant // 2551936

FIELD: medicine.

SUBSTANCE: group of inventions involves versions of a dental implant, refers to medical equipment, namely to orthopaedic dental devices bearing dental prostheses endosseously, and can be applicable for dental restoration, including the patients with a significant atrophy of the dental arch. According to the first version, the dental implant comprises a subperiosteal portion in the form of a holed metal plate, an endosseous portion in the form of a perforated plated mounted along the long axis of the subperiosteal portion, a fastening element for the dental prosthesis in the form of an implant head. The subperiosteal portion has a saddle-shaped profile shaped as an anatomical portion of the alveolar crest and represents single round-holed bearing petals mounted from both sides of the endosseous portion. The endosseous portion is cone-shaped towards an apical portion and has axially symmetrical long slots on both surfaces. According to the second version, the subperiosteal portion of the dental implant has the saddle-shaped profile shaped as the anatomical portion of the alveolar crest and represents single triangle-holed bearing petals mounted from both sides of the endosseous portion, whereas the endosseous portion represents a number of identical tooth-shaped wedges with axially symmetrical long slots on both surfaces.

EFFECT: inventions enable increasing the reliability of the primary fixation of the dental implants and reducing the number of injuries of bone and soft tissues of the alveolar crest.

2 cl, 3 dwg, 1 ex

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