Ointment for septic and open wounds

FIELD: medicine.

SUBSTANCE: ointment contains wax 13-15 wt %, glycerol 15-20 % and vegetable oil; the prepared ointment mass is exposed to ozone for 15-20 min in a yield amount of 10 mg/l.

EFFECT: invention provides the advanced healing efficacy with no side effects by reducing the time of wound cleansing from purulo-necrotic tissues.

3 ex

 

The invention relates to medicine, namely to compositions of ingredients that have medicinal purpose by external use on the human body.

Closest to the claimed ointment is an ointment for treatment for frostbite (patent RF №2478368, IPC AC 9/06, AK 36/21, AK 9/42, A01P 17/26, 2013), including wax, amaranth oil, glycerin, with the following ratio of components, mass. %: wax 13-15, glycerin 15-20, amaranth oil the rest.

This ointment is more versatile than existing in the field of its application for different types of wounds, but the main drawback is the slow cleanse wounds from pus, which delays healing effect.

The technical result of the invention is aimed at increasing the effectiveness of healing action in the absence of side effects due to the shortening of cleansing the wound of necrotic tissue.

The technical result is achieved in that ointment, including the bee product contains as bee wax product, as fat product of plant oil, as a means of activating the metabolism, glycerol, ozone in the following ratio of components, mass. %: wax 13-15; glycerin 15-20; vegetable oil the rest, with the resulting mass ointment ozonize for 15-20 min, and the ozone on you�ode is 10 mg/L.

Comparative analysis with the prototype showed that the claimed composition of the ointment differs from the known fact that the mass of ointment ozonize for 15-20 min, and the ozone output is 10 mg/L.

Ointment is manufactured as follows.

Vegetable oil heated to boiling in a steam bath, after which it added to the wax to dissolve. The resulting mass is stirred and left to simmer 5 minutes, then remove from fire, cool to room temperature, add the glycerin, mix thoroughly and the resulting mass ointment ozonize for 15-20 min, and the ozone output is 10 mg/L.

The cooled ointment is applied sterile medical spatula in a thin layer on a sterile cloth and applied on the wound surface.

The validity of the ointment more than 2 years from the date of preparation when stored in a cool dark place.

therapeutic properties of ointments are as follows.

Vegetable oil contains triglycerides and polyunsaturated fatty acids that promote tissue regeneration.

The wax used for other ointments bee products has the lowest reactivity, in the presence of triglycerides is able to allocate the wound oxidized oxygen, contributing to tissue regeneration.

Glycerin has a softening and simultaneously.�but astringent action, has a high hygroscopic and lubricating properties. When applied to the wound surface it activates metabolic processes and has hemostatic effect.

Ozone when applied topically in the form of ozonized solutions or oil, etc. has a direct oxidative effect on the membrane of microorganisms. Ozone kills virtually all types of bacteria, fungi, viruses and protozoa. While gram-positive bacteria and capsular viruses having lipid bilayer, are particularly sensitive to oxidation, in addition, ozone causes bactericidal effect, which is mediated by nonspecific activation of the protection system (activation of phagocytosis, enhanced synthesis of cytokines-interferons, tumor-necrotizing factor, interleukins, as well as components of cellular and humoral immunity). In addition, ozone restores metabolic reactions in the tissues at the site of inflammation

In addition, ozone restores metabolic reactions in the tissues at the site of inflammation and corrects the pH of the oxidation of double bonds.

The analgesic effect of ozone is due, on the one hand, the oxidation decomposition products of protein molecules, the so-called alopaticos acting on the nerve endings in the damaged tissue and determining the intensity of the pain response, on the other hand, normalizes�antioxidant system and thus reducing the amount of toxic molecular products of lipid peroxidation in cell membranes, which alter the function membranotropic of enzymes involved in the synthesis of adenosine triphosphate (ATP), the maintenance of tissues and organs, promotes epithelialization and healing.

Ointment plastic and due to the content based on voska-melanopterus mixture has a high penetration in biological tissue.

Ointment is completely harmless and has no side complications.

therapeutic effect of the ointment was tested in the whole range of changes in the quantitative content of the components.

The ointment was tested on twenty-five patients with various types of burn wounds, bedsores, trophic ulcers, open and festering wounds and chilblains.

Example 1.

Patient A., 20 years old, Diagnosis: burn 2-3 degrees in the area of the face, neck, chest, anterior surface. After 10 days of treatment with an ointment, the patient remained soft skin, slightly flushed.

Example 2.

Patient Z., 76 years old, suffering from trophic ulcers of both legs for 15 years. Was treated repeatedly in the hospital and clinics to no avail. After applying the ointment ulcers healed within 1.5 months with tender scar tissue.

Example 3.

Patient B., 56 years old, came with a bitten wound (dog bite) a month after unsuccessful treatment in a clinic. After applying the ointment, the wound healed � for 2 weeks.

Application of the ointment when frostbite gave a positive result. Very quickly starred swelling, were observed intoxication, ligation went smoothly, as the dressings do not stick to the wound surface and freely removed.

Ointment contains cheap, widely available ingredients, the composition is stable, easy to manufacture. Its healing properties can be recommended in clinical therapy in combat.

Ointment to treat sores and open wounds, including wax, glycerin, vegetable oil in the following ratio of components, mass. %: wax 13-15; glycerin 15-20; vegetable oil the rest, characterized in that the mass of ointment ozonize for 15-20 min, and the ozone output is 10 mg/L.



 

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