Method for producing befungin preparation of chaga muschroom
SUBSTANCE: method for producing Befungin, a preparation of Chaga mushroom involving extracting the milled raw material in heated water on a heating unit consisting of 3 reactors; adding cobalt salts to the extract in certain environment, mixing with ethanol, evaporating to dry residue of 20-25%.
EFFECT: method enables accelerating the production process, reducing energy demands, improving the quality and completeness of extraction, and improving the quality of the preparation.
2 dwg, 1 tbl, 1 ex
The invention relates to the production of medicines and can be used to obtain the medicines Befangen birch fungus chaga formed on the birches pathogenic parasite In Canada. The drug has a tonic, tonic, antioxidant, immunomodulatory, anti-inflammatory effect. It normalizes the metabolism and activity of the gastrointestinal tract, is symptomatic improve the General condition of cancer patients. Used in diseases of the gastrointestinal tract (hypoacid gastritis, peptic ulcer disease, polyposis of the stomach and intestines, hypokinesia of the biliary tract and intestine), and skin diseases, periodontal disease and as symptomatic agents in cancer.
The known method, comprising: obtaining a raw juice fungus, its treatment with an aqueous solution hyperazotemia polymer with a concentration of 1·10-7-1·10-20% in the ratio of 10:1 at room temperature for 0.5-1.5 h, the deposition of polyphenolic complex of a 20% solution of hydrochloric acid to a pH of 2.0-2.2 with obtaining sediment polyphenolic complex, and as hyperazotemia polymer used Boltorn 40 [RU 2425686, C1, A61K 36/06, 10.08.2011].
The disadvantage of this method is the relatively high complexity�the awn.
In addition, a method of producing a precipitated drug from birch fungus chaga by obtaining diffusion juice of fungus, of his deposition, adding 20% hydrochloric acid to pH of 2.0-2.2, to the stage of deposition by diffusion juice chagi add a water solution of hyperazotemia polymer with a concentration of 1·10-7-10-20% in the ratio of 10:1, the treatment is carried out at room temperature for 0.5-1.5 h [RU 2366439, C1, A61K 36/06, 10.09.2009].
The disadvantage of this method is the relatively high complexity.
There is also known a method of obtaining powder of fungus, including grinding of raw materials in an inert liquefied gas, swiezegowno raw material pre-treated with an inert liquefied gas for 30-60 min, then dried by vacuum sublimation to a residual moisture content of 1-8%, and the ratio of raw materials and liquefied inert gas during a pretreatment svezhezavarennogo raw materials and grinding in inert liquefied gas take(1:1)-(1:3) [EN 2167665, C1, A61K 35/78, 27.05.2001].
This method is also characterized by relatively high complexity.
Closest to the proposed prototype is a method for producing of preparation from birch fungus chaga, including heated water extraction of crushed middlings chagi (up to 2-3 mm), the Addendum to the extract �Olya cobalt, boiling down to 32-33% of total solids, mixing with alcohol-rectified to obtain the thick extract and further drying of the resulting mixture [SU 104607, A1, A61K 35/78, 01.01.1956].
The disadvantage of this method is the relatively low quality of the product because it has not provided the modes of carrying out the individual stages of the method provides increased extraction.
Grinding chagi to the size of 2-3 mm at the extraction depletes a large amount of ballast substances in the extractant and the difficulty in filtering.
The boiling of the extract up to 32-33% of total solids has its drawbacks:
the extension of the duration of production, the increase in energy costs;
- shortness of discharge from the reactor, as well as loss - settling on the walls of the reactor;
- increase the duration of the standardization process;
is the difficulty in packing the product;
- inconvenience of use for the consumer, since a thick mass of hard to dose.
The required technical result is a significant acceleration of the process of production; the reduction of energy consumption per unit of production; improving the quality of extraction; and the achievement of completeness of extraction; increase production; improve the quality of the drug.
The required technical result is achieved in that in the method of receiving�Oia drug Befangen birch fungus chaga including heated water extraction of crushed raw material, adding to the extract of cobalt salts, evaporation and mixing with ethyl alcohol, grinding of raw materials to produce particles with sizes from 7 to 15 mm, the extraction of active substances from birch fungus chaga is carried out on the battery of the 3 reactors by mixing powdered raw materials with the extractant in a weight ratio of 1:10 and soak for 1.5 hours in the reactor at a temperature of 68-72°C, then the extract is drained into the collection, add to the extraction of cobalt salts with subsequent evaporation of the extract at a temperature of 70-80°C under a vacuum of 0.06 MPa to dry residue 20-25%.
In addition, the required technical result is achieved in that in each reactor battery serves extractant 3 times, then make the replacement of depleted raw materials - fungus on fresh.
In addition, the required technical result is achieved in that the last two extraction before draining the finished drawing on fresh produce raw materials, and then the extract is drained into the collection.
The scheme of extraction (see Fig. 1 and Fig. 2) and evaporation of the extract at a temperature of 70-80°C under a vacuum of 0.06 MPa can significantly speed up the manufacturing process of the drug Befangen (up to 20% of the time for 1 batch of finished product).
Mpariwa�their hoods to dry residue 20-25% to reduce the energy consumption for the production of up to 10% and to reduce losses during unloading of the extract from the reactor, to facilitate the filling and dosing of the drug.
Grinding chagi to the optimum particle size of from 7 to 15 mm (chosen experimentally) is used to improve the extraction process and reduce the leaching of ballast substances, which increases the quality of the products.
The optimal ratio of 1:10 raw chaga and extractant allows maximum use of raw materials.
The optimum temperature range of 68-72°C in the extraction process allows to achieve a better extraction of the active substance (polyphenol complex) of chaga to 30%.
An example implementation of the proposed method, which is used in the preparation of the drug Befangen.
Produce grinding birch fungus chaga to a particle size of from 7 to 15 mm.
Extraction hoods birch fungus chaga is carried out by mixing ground chaga mushroom with purified water.
Extraction of active substances from birch fungus chaga is carried out on the battery of the 3 reactors at a temperature of from 68 to 72°C, and heating is carried out by contact with live steam or in a contactless manner to the deaf ferry with a shirt.
In the reactor P. 1 comminuted chaga mushroom and pour the purified water. Insist birch fungus chaga in P. 1 reactor for 1.5 hours at a temperature of from 68 to 72°C. In the reactor P. 2 comminuted chaga mushroom and make �eredivise extracts from P. 1 reactor. In the reactor P. 1 again poured water. Heated the contents of the reactor from 68 to 72°C. after 1.5 hours the first batch of finished extract is drained from the reactor P. 2 in the collection.
The extract of P. 1 reactor is moved into the reactor P. 2. In the reactor P. 1 again poured water.
Carry out the extraction in reactors P. 1 and P. 2 at a temperature of from 68 to 72°C for 1.5 hours. In the reactor P. 3 comminuted chaga mushroom and make the relocation extracts from P. 2 reactor. After and before movement and before discharge to the reactors produce circulation (mixing). Meal from P. 1 reactor was removed, the reactor was washed and re-load the chopped mushroom the chaga. Make relocation of extracts from the reactor P. 3 P. 1 reactor, from the reactor P. 2 P. 3 reactor. Carry out the extraction in reactors P. 1 and P. 3 at a temperature of from 68 to 72°C. After 1.5 hours, the second batch of the finished extract is discharged into the collection from P. 1 reactor. In each reactor battery serves extractant 3 times. In the P. 1 reactor at the beginning of the operating cycle pour water 3 times. The last two extraction before draining the finished drawing is carried out on fresh material, and then the extract is drained into the collection (see Fig. 1 and Fig. 2).
The next stage is adding to the extraction of cobalt salts is based on the density of the hood. Take a sample drawing, determine the density and find the necessary amount of cobalt salts.
At 20°C and a density of the exhaust 1,038 g/cm3the required amount of cobalt chloride will be 0.84 g on 1 l of the drawing, and cobalt sulfate - 0,996 g / 1 l
Cobalt salts dissolved in a small amount of an extract in an intermediate container and then pour the resulting solution into the collection.
Then spend stage evaporation to obtain a liquid extract with a solids content of 20-25%. The evaporation was conducted under vacuum of 0.06 MPa when operating the stirrer and the temperature from 70 to 80°C. the Liquid extract is discharged from the reactor in the intermediate tank.
After the analysis of the liquid extract is the Addendum in the extract of ethyl alcohol and, if necessary, purified water to obtain a product with a solids content of 15-20%. The amount of ethyl alcohol and purified water is determined by the necessary calculations, based on the analysis results.
Example of calculation
Have a sample of the extract weight 380 kg and with a mass fraction of solids 22%. It is necessary to calculate the amount of purified water and ethyl alcohol required to obtain the mass fraction of solids of 19.8%.
1. Determine the mass of Befangen after mixing:
2. Determine the mass of ethyl alcohol to 96.3% (about.d.).
Accept that the final concentration of ethyl alcohol in Befangen will be 11% (about.d.):
M2- the mass of Befangen after standardization;
It is the content of ethyl alcohol in litres per 1 kg of solution, depending on the concentration used alcohol on the table for the determination of ethyl alcohol in water-alcohol solutions (see table 1):
0,112 - the amount of alcohol in litres per 1 kg of the 11% solution,
1,1961 - the amount of alcohol in litres per 1 kg to 96.3% solution.
3. Determine the mass of purified water:
According to the calculation of a liquid extract mixed with ethyl alcohol and purified water.
After receiving positive results of this analysis, Befunge is drained from the reactor by gravity into an intermediate container with filtration through the filter-fungal. On the bottle with filtered by Beforeno gets a label stating the name of the drug, batch numbers, mass and moved to the packaging area.
A method of producing the drug Befangen birch fungus chaga, including heated water extraction of crushed raw material, adding to the extract of cobalt salts and mixing with ethyl alcohol, characterized in that the grinding of raw materials to produce particles with sizes from 7 to 15 mm, the extraction of active substances from birch fungus chaga is carried out on the battery of the 3 reactors PU�eat a mix of crushed raw material with the extractant in a weight ratio of 1:10 and soak for 1.5 hours in the reactor at a temperature of 68-72°C, moreover, in each reactor battery serves extractant 3 times and the last two extraction before draining the finished drawing to happen on fresh raw materials, then the extract is drained into the collection; add to the extraction of cobalt salts and produce evaporation at a temperature of 70-80°C under a vacuum of 0.06 MPa to dry residue 20-25%.
SUBSTANCE: invention represents the method to obtain the soluble concentrate from sideline products of reindeer antlers, comprising aqueous raw extraction, grounded up to the forced meat condition with particle size of 3-5 mm under the action of ultrasonic vibrations with frequency of 37 kHz with subsequent filtration and vacuum drying at temperature of 45°C and pressure of 0.9 atm, distinguished by the fact that the aqueous raw extraction is carried out at temperature of 35-36°C in the presence of pepsin ferment at its concentration in raw mixture: water of 0.5% during at least 3 hours, at ratio raw: water for tails 1:5, for male genital 1:4, for uteruses with embryos and amniotic fluid 1:2.
EFFECT: significant increase of final concentrate yield from sideline products of reindeer antlers.
3 ex, 2 tbl
SUBSTANCE: invention relates to method of simultaneous obtaining of two flavonoids - patuletine and its 7-O-β-D-glucopyranoside - patuletrine. Method consists in the following: milled edge petals of flower of high flavonoid sorts of tagetes patula are extracted with hexane, dried and r-extracted with chloroform, chloroform extract is concentrated, dry residue is dissolved in mixture of petroleum ether - chloroform, precipitated sediment is filtered, washed with petroleum ether and dried, obtained dry powder is dissolved in mixture chloroform - ethanol, precipitated sediment is filtered, washed with petroleum ether and dried with obtaining patuletine. Then, extraction of raw material, which remains after chloroform processing, is carried out with ethanol, alcohol extract is filtered and concentrated, after that, water residue is subjected to liquid phase extraction with ethylacetate, then, organic layer is concentrated, dry residue is dissolved in mixture chloroform - ethylacetate, precipitated sediment is filtered, washed with cooled ethylacetate, solution of hydrochloric acid in ethanol, ethanol and ethylacetate and dried, dry powder is dissolved in mixture ethylacetate-ethanol, precipitated sediment is filtered, washed with ethylacetate and dried with obtaining patuletrine.
EFFECT: method makes it possible to obtain highly pure samples of patuletine and patuletrine, as well as increase target product output.
4 dwg, 3 tbl, 4 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutical industry, namely to a method for preparing lappaconitine hydrobromide (versions) A method for preparing lappaconitine hydrobromide is implemented by extraction of Aconitum leucostomum root and herb or Aconitum septentrionale root and herb in methylene chloride in a continuous extraction apparatus that is followed by decontamination by means of flash chromatography (version 1), or extraction of a herbal raw material in a polar organic solvent followed by extract removal from the organic solvent (version 2), alkalinisation and extraction of the prepared extract in methylene chloride followed by decontamination of the extract by flash chromatography.
EFFECT: method for preparing lappaconitine hydrobromide provides simplifying the technological process, reducing its length and improving higher yield of the end product of officinal purity.
7 cl, 1 tbl, 9 ex
FIELD: food industry.
SUBSTANCE: method for production of Siberian cedar seeds liqueur (with hepatoprotective, antioxidant, antihypoxic, hypolipidemic effect) by way of maceration with ethyl alcohol usage; whole Siberian cedar seeds are loaded into the reactor, poured with 70% ethyl alcohol water solution; extraction is performed under preset conditions. The medicinal preparation with hepatoprotective, antioxidant, antihypoxic, hypolipidemic effect contains Siberian cedar seeds liqueur. Usage of the medicinal preparation as a hepatoprotective remedy.
EFFECT: liqueur has pronounced hepatoprotective, antioxidant, antihypoxic and hypolipidemic effect.
6 cl, 3 dwg, 8 tbl
SUBSTANCE: method for producing a pigment complex of bisnaphthazarin for preventing inflammatory diseases, involving demineralising commercial sea urchins' crusts and needles in an organic acid solution, separating organic acid salts and protein, applying pigment solution on a chromatographic column, washing the column with diluted mineral acid and distilled water, eluting the pigment complex, combining fractions containing the pigments, removing ethanol, lyophilising concentrate in the certain environment. The complex of pigments bisnaphthazarins for preventing inflammatory diseases.
EFFECT: complex of pigments prepared by the above method is effective for preventing the inflammatory diseases.
3 cl, 2 dwg, 2 tbl, 4 ex
FIELD: machine building.
SUBSTANCE: for extraction (leaching) of the substances extracted from the plant materials in food, chemical-pharmaceutical and other industries, for output increasing of the substances extracted from the extractable plant materials and for increasing of their concentration in the ready extraction it is suggested to provide the extractor with the extractant recirculation circuit containing devices for solid phase separation, pump, discharge tank, flowmeter, shutdown valves system, and in the extractor bottom part additionally union will be installed for continuous liquid phase supply.
EFFECT: wider possibility of return in the vessel of part of extraction after solid phase separation in specified ratio with fresh extractant, thus improving conditions of mass exchange due to decreasing of the surface tension of the liquid phase.
SUBSTANCE: method for preparing an agent possessing anti-inflammatory, diuretic and antioxidant activity, involving milling Spiraea salicifolia shoots representing a mixture of leaves, blossom and shoots, extracting them three times by gradual maceration, mixing in infusing, filtering, condensing, separating, drying in the certain environment.
EFFECT: agent shoes the pronounced anti-inflammatory, diuretic and antioxidant activity.
2 dwg, 12 tbl
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutical and consumer industry in preparing dry herbal extracts used for later colouration of textile fabrics with this extract. A method for preparing the dry herbal extract of St. John's wort involves grinding herbal raw material, extracting in water, filtering, boiling down in a rotary evaporator and drying the residual product to constant weight in a drying chamber in the certain environment.
EFFECT: method described above enables preparing the extract with dry colorant weight 25% of dry herbal raw material weight.
SUBSTANCE: method of obtaining sanguinarine and chelerythrine sulphates includes extraction of milled overground part of macleaya microcarpa and/or macleaya cordata with water aliphatic alcohol, removal of water aliphatic alcohol in vacuum, alkalinisation of water distillation residue with hydrophobic solvent, processing organic phase with sulphuric acid, filtration, washing and drying of target product, with extraction of milled raw material being carried out with water aliphatic alcohol in presence of methanesulphoacid, and solution of alkaloid bases in hydrophobic organic solvent is additionally filtered through layer of hydrophobic solvent, and target product is subjected to boiling in acetone.
EFFECT: method makes it possible to increase quality of finished product, simplify technology of production of sanguinarine and chelerythrine sulphates, and reduce the process duration.
8 cl, 14 ex
SUBSTANCE: method of bee pollen processing consists in the fact, that bee pollen is extracted with CO2 by pumping CO2, obtained fat extract is separated, remaining oil-seed meal is subjected to enzymatic hydrolysis in presence of enzyme Distizym Protacide Extra, obtained fermentolisate is separated into solid and liquid phases, solid phase is dried, liquid phase is filtered, preservative potassium sorbate and sodium benzoate are added into filtered liquid fraction under specified conditions.
EFFECT: method makes it possible to efficiently process bee pollen with obtaining fractions, characterised by microbiological purity, high degree of bioavailability, and a long storage term.
SUBSTANCE: invention represents a cosmetic preparation for skin in the form of a "water-in-oil" type emulsion, which contains water, ethanol, volatile oily component, carboxydecyltrisiloxane of formula (1): 0.1-5 wt % and one, two or more components, selected from the group, consisting of hydrophibised titanium dioxide, hydrophibised zinc dioxide and hydrophibised iron dioxide.
EFFECT: removal of powder squeakiness on the skin in the course of time after application and simultaneous improvement of absorption into the skin during application and absence of stickiness after application on the skin.
3 cl, 2 tbl, 8 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to pharmaceutical composition for treating insomnia. Said composition includes root of Polygonum multiflorum and/or its extracts, seeds of Ziziphus spinosa and/or its extracts, mulberry fruit and/or its extracts, Ganoderma and/or its extracts, lily bulb and/or its extracts, Anemarrhena rhizome and/or its extracts, root of Salvia miltiorrhiza and/or its extracts, chrysanthemum flower and/or its extracts, Poria and/or its extracts and Albizia flower and/or its extracts. Invention also relates to application of said composition.
EFFECT: claimed invention provides sedative and soporific effect, contributes to memory stimulation.
17 cl, 6 tbl, 14 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to oral hygiene preparations. An oral care composition contains a) an aqueous phase; b) stannous tin ions dissolved in the aqueous phase; c) nitrates in the aqueous phase; wherein total nitrates is that a molar amount of nitrogen measured as a nitrate in the aqueous phase makes 1.8-0.1 of the molar amount of stannous tin ions; and d) a flavouring agent. What is also presented is a method for storage and a storage container for this composition; using nitrate for stabilising oxidised stannous tin ions dissolved in the aqueous phase. What is also presented is also a version of the composition, wherein the composition is aqueous.
EFFECT: using the group of inventions stabilises oxidised stannous tin ions dissolved in the aqueous phase by the above molar ratio of nitrate and stannous tin ions.
17 cl, 2 tbl, 15 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to the pharmaceutical industry, namely to a medication for the complex therapy of patients with type 2 diabetes mellitus and a method of the complex therapy of patients with type 2 diabetes mellitus. The medication for the complex therapy of patients with type 2 diabetes mellitus contains a cleaned and dried rhizome of Curcuma longa in the form of powder with the specified size of particles. The method of the complex therapy of patients with type 2 diabetes mellitus consists of the daily intake of the cleaned and dried rhizome of Curcuma longa in the form of powder with the specified size of particles twice per day after dinner and supper at the background of the intake of pelleted hypoglycaemic agents without changing the dose and scheme of the drug therapy.
EFFECT: medication produces a direct stimulating impact on β-cells of the pancreas and ensures the development of a hypoglycaemic effect, including early stages of the disease development.
3 cl, 1 dwg, 5 tbl
SUBSTANCE: invention refers to using an oral composition containing steviol, which improves the human hair or animal fur/feather/scale look. Using steviol in preparing the oral composition of nutriceuticals or a nutrient composition for improving the human hair or animal fur/feather/scale look.
EFFECT: invention provides improving the human hair or animal fur/feather/scale look more effectively.
7 cl, 4 dwg, 5 tbl, 13 ex
FIELD: veterinary medicine.
SUBSTANCE: method comprises administering a homeopathic agent. The agent "Liarsin" is used, which is administered subcutaneously before calving into the biologically active points in the centre of the front and rear udder parts.
EFFECT: invention is highly effective for prevention of parturient paresis in cows.
4 cl, 2 tbl, 1 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to chemical-pharmaceutical industry and represents method of obtaining microcapsules of medication, which possess supermolecular properties, by method of precipitation with non-solvent, characterized by the fact that as medication applied is powder of unabi berries, preliminarily dissolved in butanol, as envelope - carrageenan, which is precipitated from solution in acetone by addition as non-solvent of ethanol and water, with the following drying at room temperature.
EFFECT: invention ensures simplification and acceleration of process of obtaining microcapsules, reduction of loss in the process of obtaining microcapsules (increase of output by weight).
2 ex, 18 dwg
SUBSTANCE: method includes the preparation of a carious cavity, opening the tooth cavity, creation of an access to root canals, extension of their orifice. Removal of a decayed material from the root canals and their drug treatment are carried out. After that, performed are: wide opening of the apical tooth orifice, mechanical and drug removal of periapical pathological exudative formations in the focus of periapical inflammation through the root canal. Before filling the canal with a filling material the gel "Lamifaren" is introduced into the focus of periapical destruction. Such introduction is performed three times after a day under temporary stopping. The gel "Lamifaren" is introduced inside in a dose of 50 g 2 times per day for 30 days.
EFFECT: application of the invention accelerates bone tissue regeneration due to the active release of an active substance calcium alginate, provides stable remission due to local and systemic detoxifying effect.
SUBSTANCE: invention relates to medicine, namely to methods of purification and health improvement of an organism. For this purpose therapeutic starvation for not fewer than 5 days in case of a 7-day programme and for not fewer than 7 days in case of a 9-day programme is carried out. The duration of a recovery period constitutes two days. Food intake is realised nine times per day each day both in the process of therapeutic starvation and in the recovery period. In the period of therapeutic starvation the first food intake includes bee products "APIGRANULES 2" in a dose of one teaspoon, "KHINAZI balm" in a dose of one teaspoon, "A-P-V" in a dose of one teaspoon, "APITOK" in a dose of one teaspoon, "Antihelm phyto" - one capsule and still mineral water - one glass. The second food intake includes a drink with ginger, lemon juice, garlic and mint, honey - one teaspoon and one glass of apple-carrot juice. The third food intake supposes an intake of bee products "APIGRANULES 2" in a dose of one teaspoon, "KHINAZI balm" in a dose of one teaspoon, "A-P-V" in a dose of one teaspoon, "Antihelm phyto" - one capsule and still mineral water - one glass. The fourth food intake includes a drink with ginger, lemon juice, garlic and mint, honey - one teaspoon and one glass of apple-carrot juice. The fifth food intake consists of tea black or green with ginger, one teaspoon of honey and one glass of apple-carrot juice. The sixth food intake consists of bee products "APIGRANULES 2" in a dose of one teaspoon, "A-P-V" in a dose of one teaspoon, "Antihelm phyto" - one capsule and one glass of still mineral water. The seventh food intake includes tea black or green with ginger, one teaspoon of honey and one glass of apple-carrot juice. The eighth food intake supposes an intake of tea black or green with ginger, one teaspoon of honey and one glass of apple-carrot juice. The ninth intake of food includes depressant tea, including mint grass, valerian root, fennel seeds, cumin seeds, epilobium or strawberry leaves and one glass of apple-carrot juice. In the recovery period in 1-st, 2-nd, 3-rd, 4-th and 6-th intakes of food the composition of products remains the same as in the process of starvation. For the fifth intake of food the patients take tea black or green with ginger, one teaspoon of honey and vegetable soup. For the seventh intake of food the patients take tea black or green with ginger, "MILK COCKTAIL WITH CHITOSAN". The eighth intake of food includes tea black or green with ginger, one teaspoon of honey, "APICAMPA" cereal. The ninth intake of food for the recovery period includes a baked apple, depressant tea. In addition, a number of procedures are carried out after each food intake during the period of therapeutic starvation and the recovery period. After the first food intake gymnastics "5 Tibetan pearls" is realised. After the second food intake exercises on training apparatuses, procedures of press-therapy, electrolypolysis and myostimulation are realised. After the third food intake exercises of therapeutic physical training or aerobics are performed. After the fourth food intake a rest in form of a walk, a halotherapy session, combined with a session of relaxation therapy are realised. After the fifth food intake a course of strip-plastic is carried out. After the sixth food intake massage by manual application with a peloid-based mixture or manual massage with honey is carried out. After the seventh food intake an infra-red sauna, shower, phytobath with medicinal herbs, honey, ginger, lemon juice is taken. After the eighth food intake a shower is taken.
EFFECT: method ensures effective health improvement of the organism with the preservation of the full value life style and a sense of a comfortable state in the starvation period, reduction of recovery period term after starvation, purification of the organism without loading on the gastrointestinal tract, weight loss, and improvement of the general state and workability of the patients.
3 tbl, 7 ex
SUBSTANCE: invention relates to medicine, namely to oncology, and can be used for the treatment of local skin I-II degree radioreactions on irradiation fields after neutron therapy in patients with head and neck malignancies. For this purpose the applications of ozonised sunflower oil with peroxide number 18% and acid number 71 mg KON/g are performed on the area of the affected skin. The impact is performed after a session of neutron therapy 1-2 times per day for 4-5 days.
EFFECT: method ensures the reduction of the number of radioreactions and skin injuries due to optimally selected parameters of the applied medication, capable of the fast arrest of pain syndrome, reduction of oedema of surrounding tissues, wound-healing action in specific irradiation conditions.
4 dwg, 1 ex
FIELD: medicine, oncology, amino acids.
SUBSTANCE: invention relates, in particular, to the development of an antitumor preparation based on natural substances. Invention relates to an amino acid preparation comprising at least one modified essential amino acid obtained by treatment of amino acid by ultraviolet radiation (UV) at wavelength 250-350 nm for 12-80 h at temperature 15-30oC or with ozone at temperature 15-25oC. The modified amino acid has no toxicity for health cells. Also, invention relates to a method for preparing such preparation. Invention provides the development of an antitumor preparation based on modified amino acids and expanded assortment of antitumor preparations being without cytotoxicity for normal cells.
EFFECT: valuable medicinal antitumor properties of preparation.
8 cl, 4 tbl, 2 dwg, 4 ex