Method of treating clinical mastitis

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to veterinary and veterinary obstetrics, and can be applied for the treatment of clinical mastitis in cows. For this purpose after evening milking for 4 days, parts of the udder with signs of mastitis are influenced with an alternating magnetic field from the magnetic-therapeutic apparatus AMnp-02 "Solnyshko". The duration of exposure constitutes 10 minutes. Mastoxidine, heated to 40°C, in a dose of 20 ml three days successively, is additionally intracisternally introduced for 3 days running.

EFFECT: method ensures an increase of the treatment efficiency due to the enforcement of mastoxidine action at deep cellular and intra-cellular levels with the acceleration of its penetration in tissues.

1 dwg, 2 tbl, 2 ex

 

The invention relates to the field of veterinary medicine, veterinary obstetrics and can be used for treatment of clinical mastitis cows with application of a magnetic field.

A method of treating patients with chronic catarrhal mastitis cows with ultrasound. The method includes the scoring of the affected lobe intensity ultrasound 0.9 W/cm2, a frequency of 880 kHz, exposure, 10 minutes and intracisternally introduction of deferol And at a dose of 10.0 ml for 3 consecutive days. Method has an analgesic effect, promotes the resorption of infiltrates, stimulates the factors of nonspecific resistance (VI Slobodyanik, VA Wigs. The use of ultrasound in chronic mastitis in cows. - M., 1988. - P. 12-14).

A disadvantage of this method of treatment efficiency is low, it is 35%-60%.

A method of treatment comprising ultraviolet irradiation with a stationary mercury-quartz lamp "Solux". The udder is irradiated twice a day for 30-60 minutes. The distance from the lamp to the udder 60-80 see the Intensity of the light flux is determined by thermal sensation of the hands placed on the irradiated portion of the surface of the animal's body (I. G. Konoplev, V. N. The shulyat'ev. Inflammation of the udder in cows. A training manual. Kirov, St. Petersburg. - 2010. Pp. 230-233).

The disadvantage of this method - PR�short period of treatment and low therapeutic efficacy.

A method of treatment using nishinasuno LTK laser radiation "Zorka". It is used topically on the affected share mode No. 2 in the morning and evening after milking, exposure for 2 minutes. The principle of action was to stimulate their own life forces of the body in self-healing (Inozemtsev, V. P., I. I. inform [the, A. G. Nezhdanov. The quantum treatment of cows at metritis and mastitis. Veterinary science. - 2000. - No. 10. - P. 9-12).

The disadvantage of this method of treatment is that the efficacy of laser treatment is to 81.9%.

The purpose of the invention: enhancing the effectiveness of the treatment, suppression of pathogenic microflora of milk, shortening the treatment, and reducing the economic costs of treatment.

This goal is achieved impact on part of the udder of animals with clinical signs of mastitis alternating magnetic field magnetotherapy apparatus Amnp-02 "Sun" in combination with the drug methoxide.

The apparatus Amnp-02 "Sun" is intended to influence for medicinal purposes in different parts of the human body an alternating magnetic field in medical, sanatorium-and-Spa institutions, as well as at home on doctor's advice. Has a low-frequency variables, and automatically changing frequency magnetic field exposure and based on therapeutic effect of changing the cha�tote pulsed magnetic fields. Possesses diverse therapeutic effects: neuro-stimulating, analgesic, anti-edematous, anti-inflammatory, vasoactive, stimulating regeneration in the damaged tissues. Magnetic therapy improves circulation, restores the clotting of blood, stimulates the outflow of secrets from the internal organs, stimulates regenerative and reparative processes in tissues (instructions for use of magnetotherapy apparatus with a low-frequency alternating magnetic field exposure Amnp-02 "Sun". Approved by Order of Roszdravnadzor No. 9642-Ol/09 "01 December 2009).

Methoxide 1% solution has a broad spectrum of antibacterial activity against gram-negative and gram-positive bacteria, Proteus, Pseudomonas aeruginosa and Klebsiella (Bacillus of Friedlander), Salmonella, Staphylococcus, Streptococcus, as well as pathogenic anaerobes. The active substance is dioxidine, which selectively inhibits DNA synthesis in microbial cells without affecting the synthesis of RNA and protein; induces structural changes of the cell wall and nucleotides bacteria, inhibits the activity of extracellular bacterial nucleases and α-toxin. Used for the treatment and prevention of clinical and latent mastitis, as well as for preventive sanitizing treatments udder in n�the beginning of the dry period in cows (instructions for use Metaxalone 1% solution for the prevention and treatment of mastitis in cows).

Our proposed method for the treatment of clinical mastitis cows is as follows: after the evening milking on the part of the udder with signs of clinical mastitis put magnetotherapeutic device Amnp-02 "Sun", the duration of the magnetic field is 10 minutes, magnet therapy course - 4 days. Additionally intracisternal enter methoxide, heated to a temperature of 40°C, at a dose of 20 ml for three days in a row.

Photo 1 shows the fixation magnetotherapy apparatus Amnp-02 "Sun".

Example 1. For the experiment was chosen 60 head of cattle diagnosed with chronic purulent-catarrhal mastitis, which on the basis of pairs of analogues were divided into experimental and control groups (n=30).

Cows first group was treated in a known manner: LTK "Zorka" externally in the area affected shares in mode No. 2, exposure of 2 minutes, morning and evening after milking to 5 days, in combination with the drug Mastie-Forte vnutriarterialno, at a dose of 8 g, once a day after milking until recovery. Cows in the second group were treated with the new proposed method: magnetic radiation by means of the device of "Sun" Amnp-02 topically to the affected area fraction for 10 minutes in the evening after milking for 4 days in complex with mystacidium, heated to 40°, at a dose of 20 ml intracisternal amazed at the proportion of 3 days. RES�the objectives of the effectiveness of these treatment regimens are summarized in table 1.

Table 1
Comparative efficacy of combined application of magnetic field and metaxalona for mastitis cows
GroupThe number of goalsThe number of affected shares udderThe number of days of treatmentRecoveredCured
goals%share udder%
First30605,5±0,62583,34676,7
Second30653,8±0,853010060100

As a result of treatment in a new way in the second group have recovered all the cows, and the first where I had used famous�th method of treatment, recovered only 83,3%, which is 16.7% less than in the first group. therapeutic course in the second group was shorter by 1.5 days.

Example 2. In cows the first and second groups (from example 1) was identified and determined by the presence of the species composition of the microflora in udder secretions share with signs of clinical mastitis before treatment and on the last day of treatment (A. D. Tretyakov, 1981. The tests were carried out according to GOST 53430-2009, gostrem 52814-2007, GOST 30347-97, GOST 10444.12-88). The research results secret of the affected udder lobes are presented in table 2.

Table 2
The presence of the species composition of the microflora in udder secretions share with signs of purulent-catarrhal mastitis
Selected microfloraIndicators
the first groupthe second group
in the 1-day treatmenton the 4th day of treatmentin the 1-day treatmenton the 5th day of the treatment
Qty% Qty%Qty%Qty%
All investigated samples65656060
The number of samples with detected mastitis pathogens, including:6295,4005591,71423,3
Streptococcus agalactiae2032,2001731,0428,6
Staphylococcus aureus27a 43.5002443,67 50,0
Fungi of the genus Candida58,1004a 7.317,1
Proteus vulgaris23,2003a 5.400
Escherichia coli813,0007a 12.7214,3

According to the results of bacteriological examination, in the second group of cows on the fourth day of treatment of samples with mastitis pathogens were not detected in comparison with the first group, this suggests that the treatment magnetotherapy apparatus Amnp-02 "Sun" in combination with mystacidium suppression of pathogenic organisms is 100%.

A method for the treatment of clinical mastitis, including the effects of alternating magnetic field on the part of the udder of animals with signs to�imicheskogo mastitis magnetotherapy apparatus Amnp-02 "Sun" after the evening milking for 4 days, the duration of exposure of 10 minutes and an additional intracisternally introduction methoxinine, heated to a temperature of 40°C, at a dose of 20 ml for three consecutive days.



 

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FIELD: medicine, pharmaceutics.

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4 cl, 6 tbl, 3 ex

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1 ex, 3 tbl

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1 tbl, 3 ex

FIELD: physics.

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2 dwg

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1 ex, 4 tbl, 1 dwg

FIELD: medicine.

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4 ex

FIELD: medicine.

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2 ex, 1 tbl

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3 ex

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2 ex, 4 tbl

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to stimulating metabolic processes experimentally. The patient is exposed to a pulse magnetic field. Thereafter, an inductor coil is applied with its north pole placed on the regions with maximum prominent trophic involvements, a projection of a distal aorta, iliac and femoral arteries. The exposure represents three 7-day courses daily every 5 days. On the first two days of the first course, the exposure length is 7 minutes, the frequency is 5 Hz, the voltage is 600 V, and also for 3 minutes at the frequency of 1 Hz, the voltage of 600 Hz. On the following two days, the voltage increases to 650 V, the exposure length increases by 1 minute at both frequencies. On the following three days of the first course, the voltage increases to 700 V, the exposure length increases by 1 minute at both frequencies. The second course is characterised by the voltage of 700 V, the exposure length increased at both frequencies on the third, fifth, and seventh sessions. The third course is performed daily at the voltage of 700 V at the maximum exposure length of 10 minutes at the frequency of 5 Hz, and of 6 minutes at the frequency of 1 Hz.

EFFECT: method enables repairing the microcirculatory vessels.

2 ex, 1 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely - to physiotherapy and gynaecology. A method involves the exposure of a projection of ovaries and transcranially in a bitemporal region to magnetic field. The above regions are exposed to magnetic field at frequency 15 Hz for 20 minutes. That is combined with the transcranial electric stimulation at pulse train repetition frequency 77Hz and amplitude 4 V. The therapeutic course is 5-7 days.

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2 ex

FIELD: medicine.

SUBSTANCE: coordination exercises are performed including a complex isotonic-isometric, isometric and isotonic exercises that focus on deep stabilising muscles of the spine. The exercises are performed continuously with small-range motions with regulated respiration: motional expiration, relaxing inhalation from six preparatory positions: sitting on an exercise ball, lying on an exercise ball, lying on one's back, lying on one's side, pronating, standing on all fours using an exercise ball and a rubber band tourniquet with a background relaxation instrumental music. A work out duration is 35-40 minutes; in the afternoon, the patient's lumbosacral region is exposed to an alternating magnetic field in the continuous mode at magnetic field induction 30 mT and length 15 minutes. The procedures are daily; the therapeutic course is 10-12 procedures.

EFFECT: method enables reducing the length of treatment, improving the spinal motor functions and patient's quality of life.

1 ex

FIELD: medicine.

SUBSTANCE: therapeutic device comprises a therapeutic element having a disposable and a reusable portion and comprising a processor connected to a temperature sensor of the heated tissue. The therapeutic element has a place to inject the preparation into the tissue in the pre-set tissue point at the specific moment of time. A processor-controlled heating element is integrated into the therapeutic element or adjoins it; the heat is applied to the tissue in the specified point over the specified period of time: before, during and/or after the therapeutic agent is administered, and the tissue is heated to the pre-set temperature, which is less than the pre-set threshold temperature. Depending on the tissue temperature, the processor stabilises heating at the pre-set temperature. The disposable portion comprises an identification element to indicate whether the portion is in use. An indicator of the therapeutic element is configured to indicate whether the specific injection point is in use.

EFFECT: using the invention enables preventing the re-injection into the same point.

17 cl, 6 dwg

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