Method for preparing dry herbal extract of st. john's wort

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutical and consumer industry in preparing dry herbal extracts used for later colouration of textile fabrics with this extract. A method for preparing the dry herbal extract of St. John's wort involves grinding herbal raw material, extracting in water, filtering, boiling down in a rotary evaporator and drying the residual product to constant weight in a drying chamber in the certain environment.

EFFECT: method described above enables preparing the extract with dry colorant weight 25% of dry herbal raw material weight.


The invention relates to pharmaceutical and light industry for preparation of dry plant extracts used for further coloring this extract textiles [1, 2].

In the patent RU 2199312 C1 describes a method of obtaining a dry extract as a medicine. This method involves adding excipients: lactose monohydrate, magnesium stearate, and so on

In the patent RU 2287338 C2 describes a method for tablets of dry extract of St. John's wort, comprising mixing a dry extract with auxiliary substances, seal, screening, processing the condensed extract excipients, including titanium dioxide and talc, followed by pelletizing.

A method of obtaining a dry extract 2192272 (2002) using as adsorbent dry powdered seaweed kelp sugary (Laminaria saccharina) and bladder wrack (Fucus vesiculosus). The disadvantage of this method is the long drying - up to 24 hours.

Known methods for producing dry extract (patent RF №2116797, RF patent №2173557) where the extractant is ethanol and water / ethanol mixture. The disadvantage of this method is the application of organic flammable liquids that require strict security measures and increase the cost of the finished extract.

D is I get dry plant extract were used the following apparatus and materials: electric mill, paper filters, rotary vacuum evaporator mark RM -1, drying Cabinet, scales.

A method includes the following steps:

1. The grinding plant.

2. Extraction of substances from the calculation of 150 grams of vegetable raw materials in 1 liter of water (1:6,6), extracted with water from dry raw material up to 1 litre for 1 hour at the boiling temperature of the solvent.

3. Filtration of the extract.

4. Evaporation of extract obtained at a rotary vacuum evaporator at a temperature of 40-45°C and the atmospheric pressure is 100 mm RT.article.

5. Drying the residue to constant weight in a drying Cabinet at a temperature of 95°C.

The process of evaporation takes place under vacuum at atmospheric pressure of 100 mm RT.article when the boiling temperature of the extract 40°C. the Evaporation in vacuum has certain advantages over evaporation at atmospheric pressure. Evaporation under vacuum gives the possibility to carry out the process at lower temperatures, which is important in the case of concentration of solutions of substances that decompose at elevated temperatures. When the vacuum increases the effective temperature difference between the heating agent and the solution that can reduce the heating surface of the device.

Obtained after evaporation of the product being dried. When drying is the process of removing moisture from the solid. In a drying Cabinet is infrakrasnoe the radiation promotes more intensive removal of moisture.

The result is a resinous substance of a dark brown colour, soluble in water, with a pleasant sweet smell, which is a complex extractive dyes Hypericum perforatum. In appearance resembles a mummy.

The yield of 25.5% by weight of dry plant materials. Developed by the author, the method does not involve the use of additional additives, expensive installations and the use of solvents such as acetone, ethyl and methyl alcohols[3, 4, 5].

The obtained dry extract of St. John's wort is highly soluble in the solvent (water), which was originally extracted.

Finished dry extract enough stored for a long time (5 years or more) at a temperature of +4 -+8°C.


1. Application No. 2009117627. A positive decision dated 26.10.2010 Asimov F. W., Shagin N. A. The way protravnogo dyeing wool fabric with vegetable dye grass bird from the mountains.

2. Application No. 2012101148. The positive decision from 13.09.2010, Shagin N. A., Asimov F. W. Way protravnogo dyeing wool fabric with vegetable dye Thistle drooping.

3. Neborak O. Y. / Chemical modification and study of the properties of natural vegetable dyes. Diss. ... K. H. N. - M. - 2005. - 120 S.

4. Anna A. D. / technology Development anthocyanin KRA is Italy from vegetable raw materials. Diss. ... K. so-called Voronezh, 2004. - 180 S.

5. Badalov E. K. / Developing ways to improve the efficiency of the extraction process and the quality of the colouring matter of vegetable raw materials. Diss. ... K. so-called Moscow. - 2000. - 130 C.

The method of obtaining dry plant extract of Hypericum perforatum, which includes grinding plant, extraction, filtering the extract, evaporation him in a rotary vacuum evaporator at 40°C and drying the residue to constant weight in a drying Cabinet, characterized in that the evaporation of the extract in a rotary evaporator is carried out at atmospheric pressure of 100 mm, the mass ratio of dry plant materials and water is 1:6.6 and the yield of dry plant extract amounts to 25.5% by weight of dry plant materials.


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