Method for monitoring of individual's health

FIELD: medicine.

SUBSTANCE: method refers to clinical diagnostics, and aims at detecting healthy individuals suffering from non-infectious chronic diseases or a predisposition thereto by an integral assessment of risk factors, a sub-optimal health status and endothelial dysfunction. A patient is presented with the questionnaire 'The Assessment of the Sub-Optimal Health Status. SHS-25' to answer, specifies his/her smoking duration and the number of cigarettes per day. Additionally, the patient's weight, height, systolic and diastolic blood pressure, blood glucose, and total blood cholesterol are measured; the vascular wall stiffness and pulse wave reflection indices are tested with a cuff. A smoker's index, the body weight index and endothelial functional values are calculated. The derived data are electronically processed in accordance with equations. The derived greatest value enables referring the person being tested to one of five groups: the optimal health status, the sub-optimal health status of a low risk of pathological conditions, the sub-optimal health status of a high risk of pathological conditions, a cardiovascular phenotype of the sub-optimal health status of a low risk of a cardiovascular pathology, a cardiovascular phenotype of the sub-optimal health status of a high risk of a cardiovascular pathology.

EFFECT: method enables assessing the health condition of the person being tested and suffering from pre-clinical disorders by detecting and assessing the risk factors and determining the sub-optimal health status.

1 ex

 

The method relates to medicine, namely to clinical diagnosis, and is designed to identify healthy individuals with non-communicable chronic diseases or a predisposition thereto.

In the world each year from non-communicable chronic diseases kill more than 36 million people, including more than 9 million under the age of 60 years (1). A systematic review of 16 randomized clinical trials have shown that regular periodic health checks did not reduce either total mortality or mortality from specific diseases (2). Prospective identification of persons in the state between health and disease and related risk factors for disease development. This condition is identified as suboptimal health status and is regarded as subclinical and reversible stage of the disease, it is important to provide timely health care (3). Screening as a method for active detection of patients with suboptimal health status, risk factors, Udachnaya conducting computer photoplethysmography with the breakdown of reactive hyperemia, at the first stage of preventive examinations gives medical examination sighting character that increases its effectiveness.

1. The known method the holistic assessment of human health through examination of each e is the COP of the system "health" health indicators (4). The deficiency is not accounted for subjective assessment of their health surveyed, a large amount of primary data for input into the system that requires the participation of trained personnel and enough time for examination.

2. The known method Quantitative method of complex assessment of the physical health of man" (5). Disadvantages of the method does not differentiate the health levels of health, a large amount of primary data for input into the system that requires the participation of trained personnel and enough time for examination.

3. Known "Method for integral evaluation of human health examination person on each element of the system of "health" and "Computer system of integral assessment of the level of health for individual prognostic surveys (XIOS)", developed on the basis of this method for health monitoring of railroad workers in automated programs for primary prevention of chronic non-communicable diseases (6). The disadvantages of the method is the large amount of questionnaires that requires the participation of trained personnel and enough time for the examination is not useful for screening.

4. There is a method of Diagnostics and forecasting prevention programs internal is olesna". Method formed the basis of the "Automated system of quantitative dynamic risk assessment the main pathological syndromes for the purposes of mass prophylactic medical examination (USERS)". Disadvantages - large amount of questionnaires, the absence of methods of functional diagnostics, the need for trained personnel by questioning(7).

5. The known method an Automated System Health Monitoring (ASMOS) (http://asmoz.osu.ru/), is used as a means of psycho-physiological control of socially significant diseases in the student's environment (8). Disadvantage - does not take into account physical illness, risk factors for chronic noncommunicable diseases, they do not evaluate the functional state of the organism, is not suitable as a screening checkups.

6. There is a method that is closest to the claimed invention, the set of essential characteristics (prototype), it is "Automated quantitative risk assessment of major pathological syndromes and conditions" (ASCOR). Includes a formal questionnaire containing questions on complaints, medical history, genetic and psychological records, to the peculiarities of labour, life, food, and a minimum of objective studies (height, weight, GARDEN, DBP, pulse rate). On the basis of specialized algorithms developed at the core the ve decision rules Bayes ' theorem, the aggregate results of the survey and the main objective indicators used to determine quantitative measures of risk the main pathological syndromes and conditions. During computer processing of the data of the questionnaires is given the quantitative equivalent of the existing risk. From 0 to 0, 74 - low risk (healthy persons), 0, 75 0, 94 - average risk (healthy persons), 0, 95 to 1 - high risk ("threatened" person). Next is the verification of the diagnosis by traditional methods of examination according to the standards of management of patients cardiac profile.

Then formed threads dispensary observation of the population: the first thread - womanifesto stage, annual examination (periodic health examination); the second flow - persons with newly diagnosed pathology according to screening (preventive examinations 2 times per year); the third flow - patients with varying degrees of compensation (9).

The disadvantage of the system ASKARS a method for screening is: a large amount of primary data for input into the system that requires the participation of trained personnel and enough time for examination, analysis syndromes; reducing the accuracy of diagnosis in the preclinical stage, the lack of objective research that reflects a modern view of non-communicable chronic diseases, it is not possible usage is to use it as a way to self-observation.

The aim of the invention is to provide a method for screening and identification of people, which causes changes in the functioning of organs and systems at the preclinical stage, when a person can show only nonspecific complaints, keeping in suboptimal health status.

This goal is achieved by the fact that the patient is responding to the questionnaire "Assessment of suboptimal health status SHS-25", find out the examined risk factors, calculate the index of the smoker, body mass index, measure blood pressure, determine the level of glucose, total cholesterol, blood; conduct computer photoplethysmography with the breakdown of reactive hyperemia followed by computer processing the received data according to the equations:

NEOS=535,2*P-0,8*Ot-4,5*Mouth-22,9*PS+12,5*CCC+8,2*PS-5,8*+6,3*Cm+3,2*IR+10,6*BMI+2,8*GARDEN+5,8*DBP-2,5*PV+6,7*IO-4,4*IO-0,6*IZH-4,7*II+46,3*Hol+22,8*CH-28485,5

SSNR=534,2*P-0,9*VZ-4,9*Mouth-23,2*PS+12,0*CCC+7,7*PS-16,1*+6,8*Cm+3,2*IR+10,5*BMI+2,8*GARDEN+5,8*DBP-2,5*PV+6,7*IO-4,5*I-1,1*IZH-4,8*II+47,5*Hol+23,2*CH-28364,1

SSVR=534,1*P-0,9*Ot-4,6*Mouth-22,5*PS+12,6*CCC+8,4*PS-15,7*+6,7*Cm+3,2*IR+10,5*BMI+2,8*GARDEN+5,8*DBP-2,6*PV+6,8*IO-4,5*I-1,2*IZH-4,6*II+47,8*Hol+23,4*CH-28366,7

SPNR=534,48*P-0,6*VZ-5,2*Mouth-23,2*PS+12,1*CCC+7,3*PS-16,3*+6,9*Cm+3,3*IR+10,9*BMI+2,9*GARDEN+5,5*DBP-2,6*PV+6,7*IO-4,5*I-1*IL-4,6*II+47,2*Hol+24,5*CH-28429,2

SFVR=536,3*P-0,6*VZ-5,3*Mouth-23,1*PS+13,3*CCC+7,1*PS-16,6*+7,2*Cm+3,2*IR+11,3*BMI+3*GARDEN+5,8*DBP-2,9*PV+6,8*IO-4,6*I-1,1*IZH-4,4*And The 2+49,6*Hol+25,6*CH-28672,9,

where neo - optimal health status, SSNR - suboptimal health status of low-risk development of pathological conditions, SSWR - suboptimal health status of high risk of development of pathological conditions, SSRRR - cardiovascular phenotype of suboptimal health status low risk of developing cardiovascular disease, SFWR - cardiovascular phenotype of suboptimal health status of high risk of development of cardiovascular disease, P - floor, VZ - age, Mouth - "fatigue", PS - "symptoms of mental status, CCC - "symptoms of the cardiovascular system", PS - "symptoms of the digestive system" - "symptoms of the immune system", Cm - total SHS questionnaire-25 IR index smoker, BMI - body mass index, CAD - systolic blood pressure, DBP - diastolic blood pressure, PV is an indicator of endothelial function, IO is the initial index of reflection of the pulse wave, I - the index of reflection of the pulse wave, IZH - source index rigidity of the vascular wall, IG - index rigidity of the vascular wall after sample Hol - total blood cholesterol, CH - blood glucose; on the basis of the highest values obtained in equations, they will be assigned to one of five groups and will receive advice on how to maintain a healthy lifestyle, correction factors figure is a, in-depth examination.

The method is implemented by the following algorithm: the patient responds to the questionnaire suboptimal health status SHS-25, find out the experience of tobacco Smoking and number of cigarettes smoked per day, the index is defined smoker; measurement of height, weight, and calculate body mass index; systolic and diastolic blood pressure; blood glucose, total cholesterol, blood; measured with a sample of reactive hyperemia stiffness of the vascular wall, the index of reflection of pulse waves before and after sampling to calculate the indicator of endothelial function; perform computer data processing in accordance with the equations:

NEOS=535,2*P-0,8*Ot-4,5*Mouth-22,9*PS+12,5*CCC+8,2*PS-5,8*+6,3*Cm+3,2*IR+10,6*BMI+2,8*GARDEN+5,8*DBP-2,5*PV+6,7*IO-4,4*IO-0,6*IZH-4,7*II+46,3*Hol+22,8*CH-28485,5

SSNR=534,2*P-0,9*VZ-4,9*Mouth-23,2*PS+12,0*CCC+7,7*PS-16,1*+6,8*Cm+3,2*IR+10,5*BMI+2,8*GARDEN+5,8*DBP-2,5*PV+6,7*IO-4,5*I-1,1*IZH-4,8*II+47,5*Hol+23,2*CH-28364,1

SSVR=534,1*P-0,9*Ot-4,6*Mouth-22,5*PS+12,6*CCC+8,4*PS-15,7*+6,7*Cm+3,2*IR+10,5*BMI+2,8*GARDEN+5,8*DBP-2,6*PV+6,8*IO-4,5*I-1,2*IZH-4,6*II+47,8*Hol+23,4*CH-28366,7

SPNR=534,48*P-0,6*VZ-5,2*Mouth-23,2*PS+12,1*CCC+7,3*PS-16,3*+6,9*Cm+3,3*IR+10,9*BMI+2,9*GARDEN+5,5*DBP-2,6*PV+6,7*IO-4,5*I-1*IL-4,6*II+47,2*Hol+24,5*CH-28429,2

SFVR=536,3*P-0,6*VZ-5,3*Mouth-23,1*PS+13,3*CCC+7,1*PS-16,6*+7,2*Cm+3,2*IR+11,3*BMI+3*GARDEN+5,8*DBP-2,9*PV+6,8*IO-4,6*I-1,1*IZH-4,4*II+49,6*Hol+25,6*CH-28672,9,

where neo - optimal status healthy is I, SSNR - suboptimal health status of low-risk development of pathological conditions, SSWR - suboptimal health status of high risk of development of pathological conditions, SSRRR - cardiovascular phenotype of suboptimal health status low risk of developing cardiovascular disease, SFWR - cardiovascular phenotype of suboptimal health status of high risk of development of cardiovascular disease, P - floor, VZ - age, Mouth - "fatigue", PS - "symptoms of mental status, CCC - "symptoms of the cardiovascular system", PS - "symptoms of the digestive system", Them - "the symptoms of the immune system", Cm - total SHS questionnaire-25 IR index smoker, BMI - body mass index, CAD - systolic blood pressure, DBP - diastolic blood pressure, PV is an indicator of endothelial function, IO is the initial index of reflection of the pulse wave, I - the index of reflection of the pulse wave, IZH - source index rigidity of the vascular wall, IG - index rigidity of the vascular wall after sample Hol - total blood cholesterol, CH - blood glucose. On the basis of the highest values obtained in equations, they will be assigned to one of five groups: optimal health status, suboptimal health status of low-risk development of pathological conditions; suboptimal when Atos health high risk of development of pathological conditions; cardiovascular phenotype of suboptimal health status low risk of cardiovascular disease; cardiovascular phenotype of suboptimal health status of high risk of development of cardiovascular disease. Surveyed after evaluating the results of the survey will receive the appropriate group recommendations for maintaining a healthy lifestyle, correction of risk factors for in-depth examination.

In this way the surveyed 500 people.

Clinical example.

The patient 34 years, height 178 cm, weight 72,5, body mass index - 22,9, smokes 2 cigarettes a day, Smoking history of 15 years, the index of smoker - 1,5, blood pressure 112 and 74 mm RT.art., the results of the computer photoplethysmography with lip breakdown: the index of reflection of the source - 81,6, the index of reflection after the sample - 65, stiffness index source - 18,8, stiffness index after sample - 9,2, an indicator of endothelial function - 18,5, cholesterol 4.4 mmol/l, glucose - 4.1 mmol/l, the result of the survey questionnaire suboptimal health status: "fatigue" - 4, "symptoms of mental status" - 2, "the symptoms of the cardiovascular system" - 1, "the symptoms of the digestive system - 1, "the symptoms of the immune system" is 0, the sum of SHS-25 - 8.

Inline data in the equations that perform calculations:

NEOS=535,2*104-0,8*34-4,5*4-22,9*2+12,5*1+8,2-5,8*0+6,3*8+3,2*1,5+10,6*22,9+2,8*112+5,8*74-2,5*18,56,7*81,6-4,4*65-0,6*18,8-4,7*9,2+46,3*4,4+22,8*4,1-28485,5=28602,89

SSNR=534,2*104-0,9*34-4,9*4-23,2*2+12,0*1+7,7*1-16,1*0+6,8*8+3,2*1,5+10,5*22,9+2,8*112+5,8*74-2,5*18,5+6,7*81,6-4,5*65-1,1*18,8-4,8*9,2+47,5*4,4+23,2*4,1-28364,1=28605,5

SSVR=534,1*104-0,9*34-4,6*4-22,5*2+12,6*1+8,4*1-15,7*0+6,7*8+3,2*1,5+10,5*22,9+2,8*112+5,8*74-2,6*18,5+6,8*81,6-4,5*65-1,2*18,8-4,6*9,2+47,8*4,4+23,4*4,1-28366,7=28604,01

SPNR=534,48*104-0,6*34-5,2*4-23,2*2+12,1*1+7,3*1-16,3*0+6,9*8+3,3*1,5+10,9*22,9+2,9*112+5,5*74-2,6*18,5+6,7*81,6-4,5*65-1*18,8-4,6*9,2+47,2*4,4+24,5*4,1-28429,2=28583,21

SFVR=536,3*104-0,6*34-5,3*4-23,1*2+13,3*1+7,1*1-16,6*0+7,2*8+3,2*1,5+11,3*22,9+3*112+5,8*74-2,9*18,5+6,8*81,6-4,6*65-1,1*18,8-4,4*9,2+49,6*4,4+25,6*4,1-28672,9=28585,54

Select the group with the highest value:

SSNR=28605,5>SSVR=28604,01>neo=28602,89>SPVR=28585,54>SPNR=28583,21

The examined suboptimal health status with a low risk of disease development. Recommended to get acquainted with the principles of a healthy lifestyle and adhere to them, to consult with your doctor to go for control screening to go through 6 months.

The proposed method (invention) provides an assessment of the status of a healthy person (best health status) and the person with health deviations on the pre-clinical stage of disease (suboptimal health status). Separately distinguished people at risk of developing the most common group of diseases - diseases of the cardiovascular system. The proposed method can find application in internal diseases, preventive medicine, sports medicine as a tool camcontrol who I am for optimal health as a tool for generating diagnostic route at the first stage of screening a healthy population; allows more efficient use of time, forces and means of the person and the health care system in the diagnosis of chronic noncommunicable diseases in preclinical stage.

Sources of information

1. Newsletter No. 355 March 2013 Article "Noncommunicable diseases".

2. Medical paper No. 43 from 14.06.13.

3. Journal of Urban Health: Bulletin of the New York Academy of Medicine doi:10.1007/s11524-011-9636-8 2011 The New York Academy of Medicine.

4. EN 2119768 C1 4. Shchedrin, A., Apogent and theory of health, Novosibirsk: Nauka, Siberian branch, 1989.

5. Determination of physical performance of a person in the clinic and sports Aulic And. Century, 2nd ed-E. - M.: Medicine, 1990, S. 17. 3. Family health and reproductive function. The conference proceedings. - M., 1993, S. 202-208.

6. Patent RU 2119768 C1 Schetinin A. N. "Method for integral evaluation of human health, 1998.

7. "Diagnosis and prognostication in programmes for the prevention of internal diseases". The dissertation on competition of a scientific degree of the doctor of medical Sciences. Polyakov, I. C. Novosibirsk, 1996.

8. Website http://asmoz.osu.ru/.

9. Some approaches to diagnosis, human health: HOWTO Panin Century A. / Kaliningr. University; EDS. - Kaliningrad, 1996. - 25 S.

6. Medico-social support of the educational process is in a multidisciplinary University Davydova N. About., Cheremisinova I. I., Nuova S. C., Barysheva E. C., Grivko N. In., Smantser T. A. Modern problems of science and education. No. 6, 2011.

Method of monitoring the health of the person using the integral assessment of risk factors, suboptimal health status and endothelial dysfunction, characterized in that the patient is responding to the questionnaire "Assessment of suboptimal health status SHS-25", find out the examined risk factors, calculate the index of the smoker, body mass index, measure blood pressure, determine the level of glucose, total cholesterol, blood; conduct computer photoplethysmography with the breakdown of reactive hyperemia followed by computer processing the received data according to the equations:
NEOS=535,2*P-0,8*Ot-4,5*Mouth-22,9*PS+12,5*CCC+8,2*PS-5,8*+6,3*Cm+3,2*IR+10,6*BMI+2,8*GARDEN+5,8*DBP-2,5*PV+6,7*IO-4,4*IO-0,6*IZH-4,7*II+46,3*Hol+22,8*CH-28485,5
SSNR=534,2*P-0,9*VZ-4,9*Mouth-23,2*PS+12,0*CCC+7,7*PS-16,1*+6,8*Cm+3,2*IR+10,5*BMI+2,8*GARDEN+5,8*DBP-2,5*PV+6,7*IO-4,5*I-1,1*IZH-4,8*II+47,5*Hol+23,2*CH-28364,1
SSVR=534,1*P-0,9*Ot-4,6*Mouth-22,5*PS+12,6*CCC+8,4*PS-15,7*+6,7*Cm+3,2*IR+10,5*BMI+2,8*GARDEN+5,8*DBP-2,6*PV+6,8*IO-4,5*I-1,2*IZH-4,6*II+47,8*Hol+23,4*CH-28366,7
SPNR=534,48*P-0,6*VZ-5,2*Mouth-23,2*PS+12,1*CCC+7,3*PS-16,3*+6,9*Cm+33*IR+10,9*BMI+2,9*GARDEN+5,5*DBP-2,6*PV+6,7*IO-4,5*I-1*IL-4,6*II+47,2*Hol+24,5*CH-28429,2
SFVR=536,3*P-0,6*VZ-5,3*Mouth-23,1*PS+13,3*CCC+7,1*PS-16,6*+7,2*Cm+3,2*IR+11,3*BMI+3*GARDEN+5,8*DBP-2,9*PV+6,8*IO-4,6*I-1,1*IZH-4,4*II+49,6*Hol+25,6*CH-28672,9,
where neo - optimal is tion health status, SSNR - suboptimal health status of low-risk development of pathological conditions, SSWR - suboptimal health status of high risk of development of pathological conditions, SSRRR - cardiovascular phenotype of suboptimal health status low risk of developing cardiovascular disease, SFWR - cardiovascular phenotype of suboptimal health status of high risk of development of cardiovascular disease, P - floor, VZ - age, Mouth - "fatigue", PS - "symptoms of mental status, CCC - "symptoms of the cardiovascular system", PS - "symptoms of the digestive system", Them - "the symptoms of the immune system", Cm - total SHS questionnaire-25 IR index smoker, BMI - body mass index, CAD - systolic blood pressure, DBP - diastolic blood pressure, PV is an indicator of endothelial function, IO is the initial index of reflection of the pulse wave, I - the index of reflection of the pulse wave, IZH - source index rigidity of the vascular wall, IG - index rigidity of the vascular wall after sample Hol - total blood cholesterol, CH - blood glucose; on the basis of the highest values obtained in equations, the subject will be assigned to one of five groups and will receive advice on how to maintain a healthy lifestyle, correction of risk factors for in-depth examination.



 

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1 tbl, 1 ex

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1 tbl, 3 ex

FIELD: medicine.

SUBSTANCE: clinical medical history data are determined as follows: body weight index (BWI), kg/m2; waist circumference (WC), hip circumference (HC), waist-to-hip ratio, type 2 diabetes mellitus diagnosed in close relatives, arterial hypertension (AH) diagnosed. The laboratory data are measured as follows: plasminogen activator inhibitor-1 (PGAI-1), nmole/l; nitrogen oxide (NO) metabolites, %; resistin, ng/ml; insulin resistance (IR), mIU/ml; triglycerides (TG), mmole/l; high density lipoprotein cholesterol (HDLPC), mmole/l; fibrinogen, mg/dl; impaired fasting glucose (IFG), mmole/l; glycosylated haemoglobin (HbAlc), %; impaired glucose tolerance (IGT), mmole/l; homocystein (HC), mcmole/l; TNF-α, pg/ml; C-reactive protein, mg/l; endothelin and fibrinogen. The derived values are scored. The total score is used to determine a risk of atherosclerosis in the patients suffering from type 2 diabetes mellitus: extremely high, high, moderate and low. Taking into account the detected degree of risk, a dosage of aspirin and statins are determined, as well as a monitored mode of blood lipids, urinary albumin and blood creatinine is specified.

EFFECT: method enables determining a degree of risk of the atherosclerosis progression as shown by the clinical medical history and laboratory data, as well as specifying individual pathogenetic therapy for the patient that leads to reducing developing cardiovascular complications.

4 tbl, 1 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, and can be used in cardiology, endocrinology, functional diagnostics and can find application in diagnostics and selecting a therapeutic approach to ischemic heart disease. The following risk factors are detected in the patients suffering from diabetes mellitus accompanied by cardiovascular disorders: blood plasma glucose, glycated haemoglobin (HbAlc), total blood plasma cholesterol, blood plasma low density lipoprotein cholesterol, blood pressure, load St segment depression, signs of carotid wall thickening, an ankle-brachial index and brachial endothelium-dependent vasodilatation as shown by the Doppler ultrasound, duration of diabetes mellitus; the derived values are scored. The derived scored values are summed up, and a risk of coronary artery atherosclerosis is stated to be low, moderate, high or very high.

EFFECT: method enables determining the risk of coronary artery atherosclerosis in the patients suffering from diabetes mellitus accompanied by cardiovascular disorders by assessing the clinical laboratory values and conducting instrumental tests, including electrocardiography, Doppler ultrasound and coronary angiography.

1 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to marine medicine. The nervous and cardiovascular functional characteristics are measured 30 minutes before and 30 minutes after a 30-metre chamber immersion to stay there for 1 hour and following 63-minute decompression. That is followed by determining an index of resistance to decompression disease (DD) in females at 20-30 years of age (IRDDF20-30) by original formula. If the derived value of the index of resistance is less than 1, a high degree of resistance to DD is stated, and the value falling within the range of 1 to 1.8 shows a moderate degree, while a low degree of resistance to DD is stated if observing the related value exceeding 1.8.

EFFECT: method enables providing the more accurate detection of the degree of individual resistance to decompression disease in females and the differentiated assessment of resistance to decompression disease in the females of a specific age by taking into account the nervous and cardiovascular characteristic values.

3 ex

FIELD: medicine.

SUBSTANCE: device for non-invasive glucose measurement in an individual comprises a single external unit, which is provided with the first part and the opposite second part for receiving the individual's body par in between. The first and second ultrasonic piezoelectric elements are mounted on the first and second parts respectively, and comprise the first and second coating membranes respectively for measuring the glucose content by ultrasound. The first and second membranes form the first and second capacitor plates respectively with a connected self-excited glucose measuring device using electromagnetic measurements. A heater and a thermal detector are mounted on the first part and separated from the first piezoelectric element for measuring glucose by the thermal characteristics.

EFFECT: using the invention enables providing the more accurate glucose measurement by a combination of the ultrasonic, electromagnetic and thermal measurement methods.

8 cl, 17 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to preventive medicine, and aims at detecting young individuals suffering from a high risk of cardiovascular diseases for the timely correction. The individuals are presented with a questionnaire to detect major risk factors of the cardiovascular diseases in accordance with the National Cardiovascular Disease Prevention Guidelines. The questionnaire results are appraised by points: if observing psychological stress 3.01-4 for males and 2.83-4 for females, 0 points are assigned; 2.01-3 for males and 1.83-2.82 for females, 1 point is assigned; 2 and less for males and 1.82 and less for females, 2 points are assigned; if the respondent doesn't smoke, 0 points are assigned; if he/she smokes less than 1 cigarette a day, 1 point is assigned; smoking 1 and more cigarettes a day implies assigning 2 points; if the patient intakes ethanol in an amount of 13.7 g a day and less, 0 points are assigned; an intake of ethanol in an amount of 13.8 g to 27.4 g a day and less enables assigning 1 point; using ethanol 27.5 g and more requires assigning 2 points; if blood pressure is less than 129/84 mm Hg, 0 point is assigned; if the blood pressure value falls within the range of 130-139/85-89 mm Hg, 1 point is assigned, and 2 points are assigned, if the blood pressure value is 140/90 mm Hg or more; if a body weight index is 24.9 kg/m2 and less, 0 points are assigned; if the range is 25-29.9 kg/m2, 1 point is assigned; the value of 30 kg/m2 provides assigning 2 points; if the physical activity is accompanied by energy burning of 3 MET/min and more over six late months and more, 0 points are assigned; the physical activity accompanied by energy burning of 3 MET/min under six late months, 1 point is assigned; if the physical activity is accompanied by energy burning of less than 3 MET/min, 2 points are assigned; if the individual consumes more than 500 g of vegetables and fruit a day, 0 point is assigned; consuming less than 500 g provides assigning 1 point, and if a daily ratio contains no fruit and vegetables, 2 points are assigned; if a rest heart rate is 50 to 69 beats per minute, 0 points are assigned; the heart rate falling within the range of 70 to 79 beats per minute provides assigning 1 point, and the heart rate of 80 beats per minute and more ensures assigning 2 points; a negative past medical history of the cardiovascular diseases with manifested ischemic heart disease or cardiovascular diseases in the male relatives in the first degree aged 55 years old or less and in the female relatives in the first degree aged 65 years old or less shows assigning 0 point, while a positive past medical history of the cardiovascular diseases makes it possible to assign 1 point. The total score is derived, and if the calculated value is 8 points and more, the respondent is referred to a group of a high risk of cardiovascular diseases, and preventive measures are recommended.

EFFECT: method enables evaluating a risk of cardiovascular diseases in the young individuals by evaluating the risk factors.

1 tbl, 1 ex

FIELD: medicine.

SUBSTANCE: patient is tested to determine clinical characteristics, each of which is scored to calculate a diagnostic index. The following clinical characteristics are determined: arterial hypertension taking into account its stage and length; diabetes mellitus, its length taking into account the patient's age and complications; ischemic heart disease and its length, cardiac angina, myocardial infarction and its length; the patient's age; compliance; smoking. The absence of any of the above characteristics is scored as 0 points. That is followed by calculating the total score; depending on the derived value, a high, moderate or low probability of the suffered silent stroke is predicted.

EFFECT: method enables establishing the presence of the suffered silent stroke reliably.

3 dwg, 4 tbl, 3 ex

FIELD: medicine.

SUBSTANCE: invention refers to medical equipment. A blood pressure measuring device under motion activity conditions comprises a pulse wave measurement sensor under a pneumatic cuff in the way of the brachial artery, and a force-balance pulse wave sensor on a diametric side of the hand. Outputs of the measurement and force-balance sensors are attached to respective amplifiers, which are attached to a subtractor, an output of which is connected to a band-pass filter, which is an output of the pressure measuring device. The device is additionally provided with the second band-pass filter, the first and second comparators, the first and second negative threshold voltage source, the first and second gate multivibrators, a logical element 2AND, a shaper for a signal informing on the sensor displacement prohibition.

EFFECT: using the invention enables eliminating false responses and blood pressure measurement errors in case of the prohibited sensor displacement by the real-time information acquisition thereon.

4 dwg

FIELD: medicine.

SUBSTANCE: technique involves the clinical-laboratory examination of a sportsman who completed heavy physical activity 12-16 hours ago. The examination extent is determined taking into account the organs and systems most vulnerable to the physical activity while deriving the prognostically significant criteria of the morphofunctional body state. The examination involves measuring and analyzing the biochemical, haematological, immunological and functional values, as well as vitamin-mineral saturation. And if the above values are stably unchanged, reliably different from the norm, nonspecific changes of the sportsman's organs and systems are diagnosed.

EFFECT: technique provides the early diagnosis of the significant changes of the organs and systems during trainings and competitions that enables taking further timely measures to prevent the further progression of pathological conditions and maintaining thereby occupational performance and achieving stable high sport results.

FIELD: medicine.

SUBSTANCE: left ventricular systolic volume as shown by echocardiography is determined in the children and adolescents suffering from essential arterial hypertension; blood serum lead is measured, and a systolic day-time hypertension time index is calculated by a regression analysis formula: SAT TI day-time=0.12+0.0035*SV+0.13*Pb blood serum, wherein SAT TI day-time is the systolic day-time hypertension time index; SV is the left ventricular systolic volume as shown by echocardiography; Pb blood serum is the blood serum lead content. If the systolic day-time hypertension time index falls within the range of 0.25 to 0.50, the form of essential arterial hypertension is considered to be labile, and if the value is more than 0.50, the stable form of essential arterial hypertension is stated.

EFFECT: method enables defining the form of essential arterial hypertension in the children and adolescents by measuring the blood serum lead content as shown by atomic absorption spectrophotometry and determining the left ventricular systolic volume according to echocardiography.

1 tbl, 3 ex

FIELD: medicine.

SUBSTANCE: heart mass relative to body weight, % (X), heart beat number (A) and pulmonary alveolar air oxygen, % (CO2) are measured. The following formula is used for calculation: α=(0.25/T)·CO2, wherein α is an entropy, %, T is an erythrocyte turnaround time with the circulating blood flow, seconds, herewith T=[(0.44·75)/(X·A)]·21.5.

EFFECT: method enables measuring the body characteristics combining the living systems that can be used to determine the biological age, the health state, to study the effect of various health disorders prevention and life prolongation means.

1 tbl

FIELD: physics; control.

SUBSTANCE: invention relates to recording time spent by a person, specifically to monitoring mobile workers in companies with a large staff and many branches and separate subdivisions. Biological information on pulse waves of all workers in the system from their sensors 1 is transmitted to a base terminal 2 and signals from all sensors 1 at certain moments in time are compared with each other in a comparison unit 3. If no matches of information from the sensors 1 are found, the comparison unit outputs a signal to a display unit 4, which indicates the number of sensors 1 which matches the number of workers in the system. If a complete match or other link between signals from two or more sensors 1 is detected, then said sensors are on the body of one person. In that case, the comparison unit 3 outputs a signal to a display unit 5, which displays unauthorised use of specific sensors by a certain worker in the system.

EFFECT: detecting unauthorised use of portable electronic devices when monitoring the number of workers and honest discharge of duties.

2 cl, 1 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely pulmonology, allergology, cardiology, functional diagnostics. Elastic and functional properties of the aorta are assessed by analysing the pulse wave characteristics recorded by non-invasive arteriography. The derived data provide a basis to calculate the principal characteristics of an arterial rigidity: the aortal pulse wave velocity - APWV and the augmentation index - AI. If observing the APWV value of 7 m/s and more and the AI value of 30% and more, the diastolic dysfunction of both ventricles is predicted.

EFFECT: method enables the timely diagnosing to begin corrective therapy in the patients suffering from bronchial asthma by assessing the pulse wave velocity in the aorta and the augmentation index.

1 tbl, 3 ex

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine. The method is implemented by generating an electric cardiosignal. Diastolic pressure (D) and an electric cardiosignal sampling are determined. An analysis window 0.4-0.5 s long is formed and moved along the signal at a pace equal to the electric cardiosignal sampling interval. Each pace involves determining statistical expectation and dispersion related to the statistical expectation in the window, and the dispersion related to the statistical expectation of each pace of the window is determined. Two variation coefficients are calculated for each pace, and a difference is calculated. The derived value is compared to a threshold of 0.5-1, and a threshold exceedance number (n1) is calculated. Then, a clock pulse, the frequency of which is equal to the electric cardiosignal sampling frequency is formed, and these pulses are counted (n2). Thereafter, n1 and n2 are related, and the derived value is divided by D. This value is transformed into a vegetation index by formula: VI=(1Dn1/n2)100%. A device for implementing the method comprises a diastolic pressure meter, a filter, a clock pulse generator, two counters, two dispersion calculators, a statistical expectation calculator, two variation coefficient calculators, a subtracter, a threshold generator, a comparator, two dividers, and a vegetation index evaluator.

EFFECT: group of inventions can provide the more reliable and accurate real-time determination of the operator's vegetation index and the based assessment of the functional state, having QRS cardiac complexes different from standard.

2 cl, 2 dwg

FIELD: medicine.

SUBSTANCE: device for the pulse data collection comprises a sensor component with the above sensor component comprising a built-in electric machine, a screw coupled with the above electric machine, a lifting structure outside from the above screw, and a sensor probe fastener in a base of the above lifting structure. The electric machine is coupled to the screw with a possibility of the latter being rotated to ensure lifting and dropping of the above lifting structure in relation to the screw. The sensor component comprises two optrons fastened in a side wall of the body. The lifting structure comprises a projecting portion passing through the above optrons when the above lifting structure is lifted or dropped. The optrons are respectively arranged in positions of the projecting portion when the sensor probe is advanced into the initial position and the extreme position. What is disclosed is a method for the pulse data collection.

EFFECT: providing the automatic pulse signal collection with giving protection ensured by the protective structure.

9 cl, 5 dwg

FIELD: medicine.

SUBSTANCE: instrument comprises an oral sample collection vessel, a detector able to detect a marker in this sample, an indicator actuated by a detector signal. The above vessel is detachably connected to an oral cavity instrument. The vessel comprises a sample collection element, a sample storage container, and a passage connecting the collection element and the container to supply the sample to the container by capillary action. The indicator is integrated into the container. The declared instrument is used to diagnose oral diseases by collecting the oral sample, detecting one or more markers in this sample and indicating the presence of one of the disease markers.

EFFECT: inventions enables establishing an accurate and fast diagnosis of the oral pathologies accompanying the daily oral care by placing the detector inside the container able to accumulate a required amount of the sample to be diagnosed.

25 cl, 1 dwg

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