Method for evaluating high risk of cardiovascular diseases in young individuals

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to preventive medicine, and aims at detecting young individuals suffering from a high risk of cardiovascular diseases for the timely correction. The individuals are presented with a questionnaire to detect major risk factors of the cardiovascular diseases in accordance with the National Cardiovascular Disease Prevention Guidelines. The questionnaire results are appraised by points: if observing psychological stress 3.01-4 for males and 2.83-4 for females, 0 points are assigned; 2.01-3 for males and 1.83-2.82 for females, 1 point is assigned; 2 and less for males and 1.82 and less for females, 2 points are assigned; if the respondent doesn't smoke, 0 points are assigned; if he/she smokes less than 1 cigarette a day, 1 point is assigned; smoking 1 and more cigarettes a day implies assigning 2 points; if the patient intakes ethanol in an amount of 13.7 g a day and less, 0 points are assigned; an intake of ethanol in an amount of 13.8 g to 27.4 g a day and less enables assigning 1 point; using ethanol 27.5 g and more requires assigning 2 points; if blood pressure is less than 129/84 mm Hg, 0 point is assigned; if the blood pressure value falls within the range of 130-139/85-89 mm Hg, 1 point is assigned, and 2 points are assigned, if the blood pressure value is 140/90 mm Hg or more; if a body weight index is 24.9 kg/m2 and less, 0 points are assigned; if the range is 25-29.9 kg/m2, 1 point is assigned; the value of 30 kg/m2 provides assigning 2 points; if the physical activity is accompanied by energy burning of 3 MET/min and more over six late months and more, 0 points are assigned; the physical activity accompanied by energy burning of 3 MET/min under six late months, 1 point is assigned; if the physical activity is accompanied by energy burning of less than 3 MET/min, 2 points are assigned; if the individual consumes more than 500 g of vegetables and fruit a day, 0 point is assigned; consuming less than 500 g provides assigning 1 point, and if a daily ratio contains no fruit and vegetables, 2 points are assigned; if a rest heart rate is 50 to 69 beats per minute, 0 points are assigned; the heart rate falling within the range of 70 to 79 beats per minute provides assigning 1 point, and the heart rate of 80 beats per minute and more ensures assigning 2 points; a negative past medical history of the cardiovascular diseases with manifested ischemic heart disease or cardiovascular diseases in the male relatives in the first degree aged 55 years old or less and in the female relatives in the first degree aged 65 years old or less shows assigning 0 point, while a positive past medical history of the cardiovascular diseases makes it possible to assign 1 point. The total score is derived, and if the calculated value is 8 points and more, the respondent is referred to a group of a high risk of cardiovascular diseases, and preventive measures are recommended.

EFFECT: method enables evaluating a risk of cardiovascular diseases in the young individuals by evaluating the risk factors.

1 tbl, 1 ex

 

The invention relates to medicine, namely to preventive medicine, and is designed to identify young people at high risk of cardiovascular disease for timely correction.

There is a method of assessing the risk of cardiovascular disease in young adults according to the scale of relative risk. (Cardiovascular prevention. National recommendations of the Committee of experts of the all-Russian scientific society of cardiologists. Journal of cardiovascular therapy and prevention.2011; 10 (6), Annex 2: 64 C.). The method consists in determining the relative risk of cardiovascular disease in young people with regard to such key factors as the level of total cholesterol, systolic blood pressure, Smoking status for. The disadvantage of this method involve the use of invasive methods for the determination of total cholesterol, which increases the time of receipt of the demands of the economic costs, slows down the start time correction of risk factors.

Known method of correcting movement patterns of young people with a high risk of developing hypertension (Application 2003102457/14, 29.01.2003). Correction motor stereotype carried out the training with the recommended individual is Noah speed walk, determined by conducting the test with walking with superiorcasino increasing speed and the subsequent calculation of the individual speed training walk by a special formula. The disadvantage of this method involve the correction of only one risk factor, the use of special equipment, the method of calculation, which increases the time and cost of the survey. The positive point is the consideration of individual characteristics of the organism.

There is a method of identifying the risk of vascular disease in young patients with arterial hypertension (Application: 2005114979/14, 17.05.2005). The method involves performing transcranial Doppler with insanely basilar artery, with evaluation of the index change of resistance of cerebral vessels, the linear velocity of blood flow, blood pressure and heart rate at rest and after running dosed physical load (DFN=75 W) on the cycle Ergometer. The disadvantage of this method consists in the correction of only one risk factor, the use of special expensive equipment, complicated calculation, which increases the duration of the examination.

There is a method of risk stratification of cardiovascular disease in young women with early astrogeodetic (Application: 2010116313/14, 23.04.2010). The method involves identifying shadowshifter risk: the maternal early menopause, the presence of arterial hypertension, the increase in total blood cholesterol, increased levels of triglycerides in the blood, increased levels of low-density lipoprotein, the reduced content of high density lipoprotein. Assess the risk factors, and when the content of low density lipoprotein in the blood greater than 4.0 mmol/l assign 4 points; family history of early menopause - 3 points; when the content of triglycerides in the blood more than 2.0 mmol/l - 2 points; in the presence of arterial hypertension - 1 point; when the content of high density lipoprotein blood less than 1.2 mmol/l - 1 point; when the content of cholesterol in the blood more than 5.5 mmol/l - 1 point. When the sum of scores from 1 to 4 define low risk, a score of 5 to 7 define medium risk, if the amount exceeds 7 define the high-risk group for cardiovascular disease. The disadvantages of the method are the stratification of cardiovascular risk in specific community of women with early estrogenicity, the use of invasive methods.

There is a method to normalize the functional reactivity of the cardiovascular system in young adults with overweight (Application: 2009148242/14, 25.12.2009). The method includes assessment of functional reactivity of the cardiovascular system at psychoana the optional load why register systolic, diastolic, srednetehnicheskoe pressure, on the basis of these indicators define the indicator functional reactivity (FIU) before and after exercise, using the formula FIU=(Map.Dean. × HR)/100 (srvc.ed.), and when the FIU is more than 20 srvc.ed. recommended dosage of static and dynamic exercise. The disadvantage of this method is the correction of only one risk factor, the dignity of the individual approach, the absence of invasive methods.

A device for predicting chronic non-communicable diseases (chronic non-communicable diseases) ("Universal system to check the status of health, 1990), which provides the definition of aerobic endurance for 30 seconds. The result of the check is a health status indicator (in digital form), as well as the category of health. Method of screening forecasting chronic non-communicable diseases and device for its implementation (Khizhnyak N. And.,Novikov Century Century Russia, 1994) are distinguished by the fact that as indicators of social and biological factors using anthropometric and immunogenetic data, performance of heredity and self-esteem of the subject. The advantage of this method is forecasting a risk of development of disease in apparently healthy individuals. The disadvantage of this method is the prob is the possibility of prediction of chronic non-communicable diseases, choose from a list of: rheumatism, hypertension, peptic ulcer and 12 duodenal ulcer, and combinations thereof. In addition, statistically significant social and biological risk factors for chronic non-communicable diseases set in the course of the research, don't use the risk factors specific to these diseases from the perspective of evidence-based medicine.

Known dissertation research Abdalla, Abouzeid Mohamed Albella (the Integrated risk assessment of chronic internal diseases of the students //abstract of dissertation of candidate of med. of Sciences, Ivanovo, 2004). The author has identified a group of high cardiac, pulmonary, psychosomatic and gastrointestinal risk among students, described the clinical features of student reactions to a stressful situation, revealed differences in the status of Central hemodynamics in hypertension, hypotension and a high level of psychosomatic and/or cardiac risk. The author recommends the use of computerized medical examinations according to the method of EDIFAR in the modification of the Ivanovo state medical Academy. However, the author uses a complex system of calculation of integral indexes risks, identifies high-risk groups with the aim of only dynamic monitoring of the health of students, not possible correction high risk x is onionskin non-communicable diseases.

Closest to the proposed method is non-invasive determination of the risk of development of cardiovascular diseases (Thomas A Gaziano, Cynthia R Young, Garrett Fitzmaurice, Sidney Atwood, and J Michael Gaziano. Laboratory-based versus non-laboratory-based method for assessment of cardiovascular disease risk: the NHANES I Follow-up Study cohort. The Lancet, Volume 371, Issue 9616, Pages 923 - 931, 15 March 2008). The method is based on the use of the leading risk factors for cardiovascular disease, no invasive procedures, using values of body mass index (BMI) instead of the traditional definition of total cholesterol, reducing the time information up to 5-10 minutes and start time correction of risk factors. But the method does not take into account the number of persons under 30 years of age.

The technical result - the development of ways to define high risk of developing cardiovascular disease, characterized by using a point system to determine the severity of the leading risk factors in young patients using non-invasive methods that reduce the time required for assessment of the cardiovascular system up to 5-10 minutes and allow early correction of the influence of risk factors.

The technical result implemented by identifying the leading risk factors for cardiovascular disease (National p the recommendations for cardiovascular prevention GFCF, 2011, http://www.scardio.ru). Assess the level of stress, history of Smoking, alcohol consumption, blood pressure (BP), body mass index (BMI), physical activity, consumption of vegetables and fruit, heart rate (HR) at rest, family history of cardiovascular disease.

The severity of the factors assessed in accordance with table 1.

Table 1. The severity of risk factors for cardiovascular diseases.

27.5 and more
The risk factorSeverity (scores)
012
The level of stress men3,01-42,01-31-2
The level of stress women2,83-41,83-2,821-1,82
The history of Smoking (cigarettes/day)noless than oneone or more
Alcohol consumption (g/ml) of ethanol per day)13,713,8-27,4
Blood pressure (mm RT.CT.)not above 129/84130-139/85-89more than 140/90
The body mass index (kg/m2)24,9 less25-29,930
The level of physical activity3 or more METERS/min the last 6 months or more3 or more METERS/min less than the last 6 monthsLess than 3 M/min
Consumption of fruit and vegetables (g/day)500less than 500no
Heart rate at rest in a minute50-6970-7980 and over
Family history of cardiovascular diseasesnegativepositive-

In accordance with the table: if the level of psychological stress 3,01-4 for male and 2,83-4 for female, assign 0 points; if 2,01-3 is La male and 1.83-2,82 for female assign 1 point; if 2 or less for males and 1.82 and less for females, assign 2 points; if the Respondent does not smoke, assign 0 points, while Smoking less than 1 cigarette per day, is awarded 1 point, while Smoking 1 or more cigarettes per day, assign 2 points; when used in the day of 13.7 grams or less of ethanol, assign 0 points, when used from 13.8 grams to 27.4 grams - 1 point, through the use of 27.5 grams or more - 2 points; if blood pressure is less 129/84 mm RT.art., assign 0 points if in the range of 130-139/85-89 mm RT.article - 1 point, if 140/90 mm RT.article and more - 2 points; if the body mass index 24,9 kg/m2and less assign 0 points, if the range 25-29,9 kg/m2- 1 point, if 30 kg/m2and more - 2 points; during physical activity, accompanied by burning energy 3 M/min or more for six or more recent months, assign 0 points, physical activity, accompanied by the burning energy of 3 METERS/min less than the last six months - 1 score, physical activity, accompanied by the burning energy of less than 3 M/min, assign 2 points; by eating 500 grams or more of vegetables and fruits per day assign 0 points, when using less than 500 g - 1 point, in the absence in the daily diet of vegetables and fruits - 2 points; if the heart rate at rest from 50 to 69 per minute assigns 0 is allow, from 70 to 79 min - 1 point, 80 per minute or more - 2 points, negative history of cardiovascular disease in case of onset of CHD or CVD in first-degree relatives of kinship in men younger than 55 years and in women younger than 65 years of age assign 0 points, with a positive history of cardiovascular disease - 1 point.

Then the points are added up. If the gained sum of points is 8 and above, the Respondent referred to the group of high risk of development of cardiovascular diseases, recommend preventive measures.

The method is tested on a group of young people aged 21-27 years, the average age of 21.9 years. The study involved 72 students, among them there were 18 boys and 54 girls. All students were issued a contract of personal consent to the passage of all stages of the research. The selection of students for inclusion in the study had an incidental character. After surveying students were examined at rest and during exercise on the "CardioVisor-:6S" (LLC "Medical computer systems. System for the rapid diagnosis of heart, RU patent for useful model №55266, 2006), according to the manual (ISS. X-64A-CardioVisor-recommendations - Scheme of examination).

We compared the index of the Myocardium at rest and during exercise, with the amount of risk factors, obtained by questionnaire and students (see table.1), and performed correlation analysis. The correlation coefficient was 0.95 to.

We found that a score of 7 and below, the index Infarction did not exceed the limit of the rules: in the rest of 13.1±0,8%, immediately after the load - 14,0±0,8%, after 2 minutes after load of 14.5±0.7% and after 4 minutes - 14,1±0,8%. In the study of students with scores of 8 and above registered the following values for the index Infarction: alone - 15,5±0,9% immediately after exercise is 18.7±1,5%, 2 minutes after loading of 17.5±1,2%, after 4 minutes after load of 15.5±0,5%. These data allow us to conclude that young people with scores of 8 and above can be attributed to the group of respondents with high cardiovascular risk.

Thus, we offer a non-invasive way ball estimate high cardiovascular risk in young people. We found that if the Respondent the sum of scores was from 0 to 7, in accordance with other objective methods of examination can be attributed to the group with low cardiovascular risk. If the sum of the scores of 8 and above, the Respondent should be attributed to the group of persons with high cardiovascular risk.

Clinical example.

The young man K., 22 years, no complaints, has the CVD risk factors: stress level (1 point), level of physical activity (2 points), heart rate at rest (1 point). The total scores for proposed SPO the training evaluation of the leading risk factors for CVD equal to 4. The index of the Myocardium to sample the exercise did not exceed 15%, immediately after the load was below 17%, which corresponds to normal levels.

The young man L., age 22 years. No complaints, has the CVD risk factors: the level of stress 2 points, the level of physical activity - 2 points, the consumption of vegetables and fruits - 1 point, HR at rest -2 score, family history of cardiovascular disease - 1 point. The total scores for our proposed method estimates the leading risk factors for CVD is 8 points. The index of the Myocardium to sample the exercise did not exceed 15%, immediately after the load has exceeded 17%, which is considered as a deviation from the norm. Therefore, the Respondent HP, with a total of 8 points identified preclinical changes in the myocardium in the test of physical exercise.

Method of assessment high risk of cardiovascular disease in young people by identifying the leading risk factors for cardiovascular disease according to the National guidelines on cardiovascular prevention, characterized in that the result of akritirian scored: if the level of psychological stress 3,01-4 for male and 2,83-4 for female, assign 0 points; if 2,01-3 male and 1.83-2,82 female, assign 1 point; if 2 or less for males and 1.82 and less for female is, assign 2 points; if the Respondent does not smoke, assign 0 points, while Smoking less than 1 cigarette per day, is awarded 1 point, while Smoking 1 or more cigarettes per day, assign 2 points; when used in the day of 13.7 grams or less of ethanol, assign 0 points, when used from 13.8 grams to 27.4 grams - 1 point, through the use of 27.5 grams or more - 2 points; if blood pressure is less 129/84 mm RT.art., assign 0 points if in the range of 130-139/85-89 mm RT.article - 1 point, if 140/90 mm RT.article and more - 2 points; if the body mass index 24,9 kg/m2and less assign 0 points, if the range 25-29,9 kg/m2- 1 point, if 30 kg/m2and more - 2 points; during physical activity, accompanied by burning energy 3 M/min or more for six or more recent months, assign 0 points, physical activity, accompanied by the burning energy of 3 METERS/min less than the last six months - 1 score, physical activity, accompanied by the burning energy of less than 3 M/min, assign 2 points; by eating 500 grams or more of vegetables and fruits per day assign 0 points, when using less than 500 g - 1 point, in the absence in the daily diet of vegetables and fruits - 2 points; if the heart rate at rest from 50 to 69 per minute assign 0 points, from 70 to 79 min - 1 point, 80 per minute or more - 2 points, negative Ana is Nese cardiovascular diseases in case of onset of CHD or CVD in first-degree relatives of kinship in men younger than 55 years and in women younger than 65 years of age assign 0 points if a positive history of cardiovascular disease - 1 point; the points are added up, if the sum of 8 points or more, the Respondent referred to the group of high risk of development of cardiovascular diseases, recommend preventive measures.



 

Same patents:

FIELD: sports.

SUBSTANCE: circle on the monitor screen is presented to the subject, on which a mark and a point object is placed. The point object moves at a predetermined speed along the circle. The testee stops the movement of the point object along the circle at the time of the proposed coincidence of its position with the mark by pressing the "Stop" button. Then the mismatch error of the point object and the mark is calculated. This is the time of trailing error with a positive sign or anticipation with a negative sign. After the predetermined time, the motion of the point object along the circle is resumed. The described procedure is performed the specified number of times. The order statistics of mismatch errors of the point object and marks is created. The range of the order is calculated by the formula: R=tmax-tmin. The ratio of the largest member of the order statistics tmax to the range R is calculated, multiplied by 100. The maximum absolute value of the prediction error |tpred.max| is determined. The lower quartile (25% quantile) of the maximum absolute value of the prediction error |tpred.max| is calculated. The percentage P of the absolute values of the prediction errors is determined, which are in the lower quartile of the maximum absolute value of the error |tpred.max|. Rating P is calculated as the reciprocal number of the arithmetic mean of the range R, the ratio of the largest member of the order statistics tmax to the range R, multiplied by 100, and the percentage Per of the absolute values of prediction errors which are in the lower quartile of the maximum absolute value of the prediction error |tpred.max|, multiplied by 100, according to the formula: P=100×1/(R+100×tmax/R+Per)/3=300/(R+100tmax/R+Per). The testee who has a higher rating is regarded as the most promising and able to show better results in upcoming competitions.

EFFECT: increasing reliability of determining the rating of combat athletes by evaluating the ratio of excitation and inhibition that characterises the speed capabilities and accuracy of motor actions.

10 dwg, 3 ex

FIELD: medicine.

SUBSTANCE: invention refers to sports medicine and aims at assessing a playing sportsman's physical actions accuracy. A sportsman being tested is presented a circle on a display with a mark and a point object moving at a specified speed round the circle. The sportsman being tested follows the point object travelling and stops it moving round the circle by pressing a Stop button once seeing an assumed matching of the moving point object and the mark. That is followed by calculating a matching error of the point object and the mark - a lag time with a positive sign or a lead time with a negative sign, and proceeding with moving the point object round the circle after some time. The sportsman being tested performs the described procedure for the specified times; a static series of the matching errors of the point object and mark is plotted; a range of the series is calculated, and a segment limited by the greatest and smallest members of the static series is marked on a number line. The physical actions accuracy of the sportsman being tested is assessed by a numerical line position of the segment limited by the greatest and smallest members of the static series of the matching errors of the point object and mark closest to a symmetry of a relatively zero point and the smallest value of the range of the matching errors of the point object and mark.

EFFECT: method enables providing the more reliable assessment characterising the playing sportsman's physical actions accuracy by instrumental measurements.

12 dwg, 4 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine and can be used for the correction of gynoid obesity. That is ensured by typing an eating disorder to be psychologically corrected. A diet therapy is prescribed with a caloric value determined by reducing a patient's habitual daily average caloric requirement per a percent equal to the patient's body weight index. That is combined with a low-carbohydrate diet with the carbohydrate content reduced to 40-60 g/day for 2 weeks. That is followed by prescribing a low-fat diet with the fat content reduced to 40-60 g/day for 10 weeks with avoiding fast assimilated carbohydrates having a glycaemic index of more than 50. The diet therapy cycle is repeated. That is combined with graduated aerobic physical exercises with no weight and resistance for the muscle groups of the lower body. There are also performed muscle-strengthening load exercises for the muscle group of the upper body promoting muscle fatigue. Between and after the graduated physical exercises, there are performed prolonged aerobic physical loads at least 5 days a week for 40-60 minutes. That is combined with the drug-free procedures aiming at improving the regional blood flow, increasing gluteofemoral and lower extremities muscle tonus. The low-fat diet involves administering health aids from the group of intestinal membrane-bound alpha-glucosidase and pancreatic alpha-amylase inhibitors. The course of the obesity correction involves administering catechin-containing preparations or biologically active additives. From the second month from the beginning of the obesity correction, the patient's face is exposed to full-spectrum natural or artificial light at intensity of not less than 2,000 lux for 1-2 hours a day simultaneously or alternatively with the physical loads.

EFFECT: method provides the effective weight reduction in the patients with gynoid obesity with reducing side effects.

5 cl, 8 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, forensic medicine, diagnostic measurements, including in investigative practice. An interactive psychophysiological testing (PPT) involves presenting a person being tested test questions, determining, analysing the psychogenesis parameters with using the person's physical parameter sensors, indicating the results and estimating. The test questions are typed as follows: first-version questions Q1, second-version questions Q2, neutral questions N. The questions Q1 and Q2 have an alternative meaning and equal power and are characterised by an equal presentation time, a consistency of comparing the questions according to the alternative versions, a minimised subjective personal effect of the PPT test expert by sound colour and level, an unconscious emotional support on the person's question perception, as well as an identity of putting the questions to be compared, their length and a fixation of the meaningful word and/or word combination in similar segments of both questions to be compared. The test is put in accordance with a concatenation as follows X:0→C,…,C→Q11.Q21→N→ →Q21.Q22→N→…→Q1n.Q2n→N, wherein X is a person's identification index; 0 is a non-estimated zero question; C is a question relieving an expectation stress; Q1i is the first-version question, wherein i=1, 2,…, n; Q2i is the second-version question, wherein i=1, 2,…, n; N is a neutral question; n is a number of specific circumstances of the event or action; ":", "→", "." are devisors. The questions are put taking into account the staging of the tested event, including the confirmed facts or data only and excluding the expert's conjectures or versions. The results are used to state one of the two alternative versions and to estimate the respective status of the person being tested. The psychogenesis is determined and analysed with using a polygraph, while putting the questions of the two alternative versions, indicating and processing the PPT data are conducted with a computer with relevant software.

EFFECT: method provides higher information value, accuracy, reliability, objectiveness of the PPT results as compared to the previously known tests up to 90-95% with avoiding the distortion and ambivalence of the results.

5 cl, 1 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to cardiology, and can be used for detecting individuals with a risk of the hypertensive disease. Regulatory relative risk of the disease, as well as standard multivariable personality test scores are determined for 10 years in apparently healthy males by the core examination, and a relation curve is plotted with using the scores: neurotic overcontrol - over 45 points, pessimistic attitude - over 49 points, rigidity - over 58 points, anxiety - over 67 points, and individuality - over 50 points. The scale scores are determined in the patient, and the curve is used to evaluate an individual relative risk of the hypertensive disease for the following 10 years in the patient.

EFFECT: method enables fast evaluation of the risk of this disease directly at the doctor's in a specific patient and detecting the individuals with the high risk of the hypertensive disease for the purpose of taking timely preventive measures.

1 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to carrying out psychophysiological studies, e.g. analysing the individual's psychophysiological responses, and can be used in medical purposes, advertising industry, functional diagnostics, education science, psychology, judicial practice and criminal science. Current normal baseline physiological parameters of a person being tested are recorded by means of a polygraph. That is followed by forming a number of independent conceptual blocks of visual information to be presented to the person being tested on a demonstration monitor of an eye motion recording device to assess the subjective significance of the visual information. An eye position, motion, a path of motion and fixation lengths are recorded; zones of preferential passive concentration fixation are recorded. The derived data are analysed to select a primary gaze zone and to determine a gaze length. Visual information elements drawing much attention are determined; when presenting the visual information by means of the eye motion recording device, synchronous measurements of the physiological parameters of the person being tested are taken by using blood pressure contact sensors, photoplethysmographic measurement, galvanic skin response, upper and lower respiration pressure transducers, tremor sensors connected in turn to a sensor unit of a polygraph recording and processing the signals supplied from the sensors. The physiological parameter variations of the person being tested are assessed by comparing an excursion of their current values from the pre-recorded baseline values; the physiological parameter variations of the person being tested specific for perceiving the subjectively significant information and being simultaneous with the primary gaze moments are used to detect the visual information elements having the most emotional impact on the person being tested. Thereafter, the qualitative emotional assessment is ensured by distributing the detected visual information elements according to the pre-set parameters into a sequence with opposite coordinates in the form of verbal antonyms with using a semantic differential method.

EFFECT: method enables providing more accurate psychophysiological studies related to assessing the information perception, assessing the exposure of the visual information and its significance for the individual by recording the physiological parameters and using the semantic differential method.

FIELD: medicine.

SUBSTANCE: score rating of a medical history, neurological and psychiatric findings, and psychophysiological testing is carried out with assigning 0 points with no burdened medical history, focal symptoms and neurological clinical pattern of diseases, psychic diseases, unfavourable social environment observed. If observing one or two signs of mentioned above, 1 point is assigned. If more than three signs of mentioned above are observed, 2 points are assigned. A Luscher colour test is used to assess an autogenous norm, a vegetative and personal balance, a working capacity, a heteronomous or autonomous nature and a concentricity and excentricity. Emotionality, anger, joy and emotion control are measured by an emotional excitement scale. A degree of stress load is assessed by an Anderson life event scale. A simple hand-eye response is used to assess a functional level of the system, a response stability and a level of functionality. That is followed by detecting deviant trends by assigning 0, 1 or 2 points for each parameter depending on its value with all the points further summed up and no deviant trends in the behaviour diagnosed in case of 0 to 13 points collected; with a borderline case at 14-17 points; deviant trends in the behaviour at 18-26 points.

EFFECT: method enables objective assessment of the individual's behaviour by studying the neurological and psychiatric states and the psychological and psychophysiological findings.

6 tbl, 3 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to gastroenterology, and can be used for providing the higher clinical effectiveness in the patients suffering dyspepsia syndrome combined with overweight. The method involves measuring an anxiety level (HARS) and a depression level (HDRS) according to Hamilton rating scales, assessing nutritional status by bioimpedancemetry, a degree of manifestation of sleep disorders, measuring glucose, testing glucose tolerance, immunoreactive insulin, cholesterol, high-density lipoprotein (HDLP), triglyceride in venous blood. If the patient is observed to suffer dyslipidemia and impaired glucose tolerance or variations of immunoreactive insulin, the preparation Dibikor is administered in a dose of 500 mg a day for three months. The patient suffering dyslipidemia and both of the disorders stated above requires administering Dibikor 1000 mg a day for three months. If the patient suffers an overweight with a body weight index falling within the range of 27 to 29.9 standard units and an active cell mass (ACM) percentage of 45 to 55 per cent as shown by bioimpedancemetry, the preparation Dietressa is administered in a dose of 1 tablet 3-4 times a day for three to six months. If the patient suffers an overweight with a body weight index falling within the range of 27 to 29.9 standard units and an active cell mass (ACM) percentage of 45 to 55 per cent as shown by bioimpedancemetry, the preparation Dietressa is administered in a dose of 2 tablet 3-4 times a day for three to six months. If the patient suffers mild and moderate sleep disorders and shows an emotive type of eating behaviour combined with mild affective disorders, the anti-depressant Valdoxane in a single dose of 25 mg a day for the night for two weeks. The course of the disease is followed by the anxiety and depression levels two weeks after the beginning of the therapy, with the positive progression of the diseases, the 25mg dose of Valdoxane remains unchanged to the end of the therapeutic course for three to six months. If no progression is exhibited, the dose is to be increased to 50 mg a day, and the therapy is continued from four to eight months. If the patient suffers severe sleep disorders and shows an emotive type of eating behaviour combined with moderate affective disorders, the anti-depressant Valdoxane in a single dose of 50 mg a day for the night for two to three months.

EFFECT: in each specific case, the method enables providing faster reduction of the clinical symptoms, including body fat weight reduction and active cell mass and water normalisation, normalising circadian rhythms of the vegetative balance, as well as prolonging the remission.

3 tbl, 2 ex

FIELD: physics.

SUBSTANCE: method employs a device in the form of a stand with two telescopic posts with induction sensors. A metal sphere moves on a channel at an angle of 5° and when the sphere passes the first induction sensor, an electrical signal is generated which triggers an electric stopwatch, and when the sphere passes the second induction sensor, the stopwatch stops. The second induction sensor is turned off and the test subject stops the stopwatch at the moment of seeing the sphere cross the finishing line by pressing a button. The reading of the stopwatch is the visual-motor reaction time. From 50 to 100 tests are carried out, which include recording all attempts by a test subject, including premature pressing of the button, constructing a personal bar chart for each test subject and selecting a standard criterion for evaluating and comparing the visual-motor reaction.

EFFECT: method increases accuracy and objectivity of evaluating visual-motor reaction to movement of an object in space.

4 dwg, 1 ex

FIELD: medicine.

SUBSTANCE: test is carried out by an application of a combined approach with simultaneous application of isometric and psychoemotional stress. Isometric stress is performed by means of two ring expanders, which a patient compresses in each hand with the maximal effort for the maximally possible time interval - usually for 2-3 minutes. In the process of performing an isometric test additional psychoemotional stress in the form of constant psychological setting of the patient to the maximal pressure of the hand expanders for the entire test is carried out. Simultaneously a registration of echocardiographic scans is performed from the apical access in a projection of a four-chamber and two-chamber section with an application of 16-segmented model in a combination with ECG AND AP registration.

EFFECT: method makes it possible to increase an accuracy and self-descriptiveness of non-invasive ultrasonic diagnostics of ischemic heart disease in clinical practice due to the creation of the powerful synergic effect from two stressing factors.

FIELD: medicine.

SUBSTANCE: invention refers to medicine, forensic medicine, diagnostic measurements, including in investigative practice. An interactive psychophysiological testing (PPT) involves presenting a person being tested test questions, determining, analysing the psychogenesis parameters with using the person's physical parameter sensors, indicating the results and estimating. The test questions are typed as follows: first-version questions Q1, second-version questions Q2, neutral questions N. The questions Q1 and Q2 have an alternative meaning and equal power and are characterised by an equal presentation time, a consistency of comparing the questions according to the alternative versions, a minimised subjective personal effect of the PPT test expert by sound colour and level, an unconscious emotional support on the person's question perception, as well as an identity of putting the questions to be compared, their length and a fixation of the meaningful word and/or word combination in similar segments of both questions to be compared. The test is put in accordance with a concatenation as follows X:0→C,…,C→Q11.Q21→N→ →Q21.Q22→N→…→Q1n.Q2n→N, wherein X is a person's identification index; 0 is a non-estimated zero question; C is a question relieving an expectation stress; Q1i is the first-version question, wherein i=1, 2,…, n; Q2i is the second-version question, wherein i=1, 2,…, n; N is a neutral question; n is a number of specific circumstances of the event or action; ":", "→", "." are devisors. The questions are put taking into account the staging of the tested event, including the confirmed facts or data only and excluding the expert's conjectures or versions. The results are used to state one of the two alternative versions and to estimate the respective status of the person being tested. The psychogenesis is determined and analysed with using a polygraph, while putting the questions of the two alternative versions, indicating and processing the PPT data are conducted with a computer with relevant software.

EFFECT: method provides higher information value, accuracy, reliability, objectiveness of the PPT results as compared to the previously known tests up to 90-95% with avoiding the distortion and ambivalence of the results.

5 cl, 1 dwg

FIELD: medicine.

SUBSTANCE: invention refers to agents for non-contact respiratory monitoring. A method for detecting a patient's expiration to inspiration variations or vice versa involving the stages of emitting an electromagnetic signal towards the patient and receiving the signal reflected from the patient, transforming the reflected signal to produce the first signal, dephasing the reflected electromagnetic signal and transforming it to produce the second signal, using a computing unit to detect simultaneous first zero transients in a time derivative of the first signal and in a time derivative of the second signal, simultaneous second zero transients in the time derivative of the first signal and in the time derivative of the second signal, and simultaneous third zero transients in the time derivative of the first signal and in the time derivative of the second signal, determining the first and second vectors and calculating their scalar product as an indicator value for the patient's expiration to inspiration variations or vice versa comparing the indicator value to the pre-set threshold value and specifying the patient's expiration to inspiration variations or vice versa, if the indicator value is less than the threshold value. A device for implementing the method involves a two-channel Doppler radar sensor and the computing unit.

EFFECT: using the invention enables providing more accurate measurement and detection of the respiratory rate.

6 cl, 6 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to surgery, and can be used in cholecystectomy in patients with cholelithiasis. That is preceded by determining a patient's body weight index (BWI), glycaemia, glucosuria; blood pressure is measured; spinal osteochondrosis and gonarthrosis are detected. The derived results are assessed and scored. If the BWI equals to 28-30 kg/m2,10 points are assigned. If the BWI equals to 30-35 kg/m2,15 points are assigned. If the BWI is more than 35 kg/m2,20 points are assigned. If glycemia is more than 5.5 mmole/l, 3 points are assigned. If the patient suffers from glucosuria, 5 points are assigned. Arterial hypertension of more than 140/190 mm Hg requires assigning 3 points. The detected spinal osteochondrosis is assigned with 3 points, diagnosed gonarthrosis is assigned as 3 points. The derived points are summed up. If the total score is 23, a cholecystectomy with a biliopancreatic diversion is performed. If the total score is 14 to 22 points, laparoscopic cholecystectomy is performed. If the derived value makes 13 points, conventional cholecystectomy is performed.

EFFECT: invention provides selecting the type of cholecystectomy taking into account the metabolic status and a degree of obesity and as a consequence, normalizing the body weight and compensating the components of the metabolic syndrome.

2 tbl, 3 ex

FIELD: oil and gas industry.

SUBSTANCE: treating bronchial asthma (BA) in a child suffering from a mild, moderate or severe episode involves measuring a peak expiratory flow rate (PEFR). The child's age, height and sex are stated. The derived data are used to determine the adequate peak expiratory flow rate. That is followed by calculating the peak expiratory flow rate coefficient by specific formula. The following data of the past medical history are taken into account: the child's duration of the disease, the length of basic therapy, completed months, for one year preceding the acute period of the disease, as well as the presence of allergic diseases in immediate maternal and paternal relatives. A severity of the BA episodes is assessed. Each value derived from the past medical history is assigned with numerical values reflecting their prognostic significance. Heart rates are measured. Cardiointervalography is performed, and a vagosympathetic balance coefficient is determined. That is followed by calculating a risk of cardiohaemodynamic disorders (CHD) taking into account the above criteria by specific formula. If CHD<0.34, Fenoterol selective β2-adrenoceptor agonist is selected as a bronchial spasmolytic in the acute period of the disease. If 0.34≤CHD≤0.46, ipratropium bromide m-cholinoblocker is selected as the bronchial spasmolytic. If CHD>0.46, combined ipratropium bromide + Fenoterol is used as the bronchial spasmolytic.

EFFECT: reduced number of cardiovascular complications in the above category of children.

3 part-s

FIELD: medicine.

SUBSTANCE: quick recording and remote transmission of the physiological parameters of human and animal cardiovascular and respiratory systems experimentally is enabled by using a receiver comprising three recording units of signal picking-up and transmission from three patients or animals simultaneously. Each of them comprises three piezoelectric detectors for ECG recording and one strain gauge for respiration depth and rate recording - a respiratory potential. The receiver is provided with a bioelectrical amplifier, an analogue-to-digital converter, RS485 interface with a board providing digital signal coding, conversion and transmission in the form of a radio signal. The latter is trapped by means of Bluetooth adapter with using a radio signal receiving and ECG and respiratory potential transmission unit. Each unit channel is checked up to receive signals from its recorder and to transmit to an ECG and respiration processing and storage unit arranged at a distance up to 30 m from the recorder. It comprises a laptop with a screen displaying one channel of cardio signal and respiratory potential channels independently from each patient or animal. Each patient or animal's data can be saved as a separate file on the signal processing and storage unit.

EFFECT: method provides fast, qualitative real-time recording of the physiological parameters with creating the conditions of a distant control of the patients both in hospitals and polyclinics, and in remote locations, in emergency and other abnormal situations.

7 dwg

FIELD: medicine.

SUBSTANCE: method enables a cycloergometric pre-measurement of exercise tolerance according to PWC170 test, a minute pulmonary ventilation (MPV) by means of pneumotachography, and arterial oxygenation by means of an ear sensor of an oxyhemograph. If observing a decrease of exercise tolerance at power less than 1 W/kg for 2 minutes, an increase of MPV more than 350% of initial values, with an increase of arterial saturation more than 98%, a treatment starts with a manual therapy covering spinal motion segments in the number of 3 procedures every two days. That is followed by a balneotherapy in the form of thermal low-radon siliceous baths at temperature 38°C, for 10 minutes in the number of 6 procedures within the therapeutic course.

EFFECT: method reduces probability of chronic processes in bronchi, reduces rate of recurrent bronchitis ensured by normalising the external respiration function by eliminating the functional blocks in the spinal motor segments.

FIELD: medicine.

SUBSTANCE: invention can be used for diagnosing alexithymia in patients with chronic obstructive pulmonary disease (COPD) complicated with chronic cor pulmonale. That is ensured by evaluating clinical-anamnestic data, determining respiratory function, blood gas, and a patient's pulmonary hemodynamic status. An alexithymia value is calculated by the certain formula and used to state the presence or absence of alexithymia in the patient, or the presence of psychopathological borderline cases.

EFFECT: diagnosing alexithymia without using the known alexithymia scale leading to the higher clinical and preventive effectiveness and improved disease prognosis in the COPD patients.

2 ex

FIELD: physics.

SUBSTANCE: apparatus (1) for detecting pulse wave and breathing cycle signals of a person has two current-conducting electrodes (2, 3) to be attached to the human body, a first (4) and a second (6) operational amplifier, an amplitude detector (5), a switched frequency-dependent voltage divider (8) and a microcontroller (7). The electrodes (2, 3) are connected in the negative feedback circuit of the first operational amplifier (4). The microcontroller (7) is configured to generate a high-frequency carrier signal at the output of a first input/output port (L). The upper (10) and lower (11) arms of the voltage divider (8) are formed by two circuits, having a common end at the mid-point of the voltage divider and two separate ends. The second operational amplifier (6) and the voltage divider (8) form an active band-pass filter with upper and lower cut-off frequencies defined by parameters of the upper (10) and lower (11) arms of the voltage divider (8), respectively. The frequency response of such a filter when the second input/output port (M) of the microcontroller (7) is connected to zero potential enables signal detection in a frequency band which corresponds to the frequency band the pulse wave signal, and enables signal detection in the frequency band corresponding to the frequency band of the breathing cycle signal when the third input/output port (N) of the microcontroller (7) is connected to zero potential.

EFFECT: detecting pulse wave and breathing cycle signals of a person based on measuring the impedance of a body area using a simple non-adjustable electrical circuit.

14 cl, 12 dwg

FIELD: medicine.

SUBSTANCE: invention relates to medical equipment. A medical sleep-disordered breathing detector comprises an adhesive plaster for attaching the detector to a human body, a microphone for controlling respiratory murmur, and logical units for analysing respiratory murmur. The microphone is coupled with the logical units to transmit signals. The microphone and logical units are integrated into the adhesive plaster. The logical units are connected with output media for respiratory murmur analysis result. With the detector fixed on the human body, the microphone is immediately adjacent to the neck skin around the carotid artery and/or on the chest.

EFFECT: using the invention enables the unassisted domestic control of respiratory disturbances to be early detected.

9 cl, 1 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine. A portable device for the noncontact random check of patient's vital values comprises: a distance sensor for series detection of a time range of the patient's chest, a respiratory rate calculator for respiratory activity measurement derived from the detected time range. Besides, the device comprises two handles so that the patient holds the device with both hands so that the distance sensor is directed to the patient's chest. The handles comprise ECG recording electrodes. The device comprises an optic sensor for photoplethysmographic measurement which is placed so that the patient holding the device automatically puts a finger on the optic sensor.

EFFECT: invention provides higher usability and simplicity of the random check of the patient's respiration ensured by guiding the distance sensor onto the patient's chest with two hands.

14 cl, 6 dwg

FIELD: sports.

SUBSTANCE: circle on the monitor screen is presented to the subject, on which a mark and a point object is placed. The point object moves at a predetermined speed along the circle. The testee stops the movement of the point object along the circle at the time of the proposed coincidence of its position with the mark by pressing the "Stop" button. Then the mismatch error of the point object and the mark is calculated. This is the time of trailing error with a positive sign or anticipation with a negative sign. After the predetermined time, the motion of the point object along the circle is resumed. The described procedure is performed the specified number of times. The order statistics of mismatch errors of the point object and marks is created. The range of the order is calculated by the formula: R=tmax-tmin. The ratio of the largest member of the order statistics tmax to the range R is calculated, multiplied by 100. The maximum absolute value of the prediction error |tpred.max| is determined. The lower quartile (25% quantile) of the maximum absolute value of the prediction error |tpred.max| is calculated. The percentage P of the absolute values of the prediction errors is determined, which are in the lower quartile of the maximum absolute value of the error |tpred.max|. Rating P is calculated as the reciprocal number of the arithmetic mean of the range R, the ratio of the largest member of the order statistics tmax to the range R, multiplied by 100, and the percentage Per of the absolute values of prediction errors which are in the lower quartile of the maximum absolute value of the prediction error |tpred.max|, multiplied by 100, according to the formula: P=100×1/(R+100×tmax/R+Per)/3=300/(R+100tmax/R+Per). The testee who has a higher rating is regarded as the most promising and able to show better results in upcoming competitions.

EFFECT: increasing reliability of determining the rating of combat athletes by evaluating the ratio of excitation and inhibition that characterises the speed capabilities and accuracy of motor actions.

10 dwg, 3 ex

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