Method and device to monitor process of injury treatment

FIELD: instrumentation.

SUBSTANCE: invention relates to facilities for monitoring of injury treatment process. A monitoring device comprises a unit of injury nitrogen oxide level monitoring, a unit of controlling signal generation by means of comparison of a nitrogen oxide level with preset threshold and unit of correction of light dosing for injury treatment, at the same time the monitoring unit is designed to detect magnetic field produced as a result of transition from Fe2+ into Fe3+, production of Fe3+ level in accordance with magnetic field, calculation of met Hb level in accordance with the level of Fe3+ and calculation of nitrogen oxide level in accordance with proportionate ratio between the level of met Hb and level of nitrogen oxide. The injury treatment device comprises several sources of light and a monitoring device.

EFFECT: using this invention makes it possible to correct treatment dose more accurately and conveniently, with minimum side effects.

7 cl, 4 dwg

 

The SCOPE of the INVENTION

The invention relates to a method and apparatus for controlling the treatment process damage.

BACKGROUND of the INVENTION

Pain is bassiliades effect due to any damage. Also the pain in the joints is the cause of serious disability that affects daily activities and performance, in particular osteoarthritis contributes to pain in the joints in a large proportion of elderly.

For the temporary relief of pain prescribed drug therapy, such as cream with capsaicin, acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs), but it is associated with serious side effects. Physiotherapy such as heat treatments, massage, acupuncture and manual therapy may relieve pain for a short time, but usually they are expensive and require the involvement of qualified personnel.

Currently, in the field of physical therapy is quite popular phototherapy systems. However, in the process of phototherapy intensity/dosage of light can be corrected only through periodic on and off phototherapy systems manually, which is inconvenient and inaccurate.

The INVENTION

The purpose of this invention is to provide a method for controlling process is com treatment of damage.

The invention relates to a method of control over the treatment process damage, and the method includes the following stages:

monitoring the level of nitric oxide damage,

generating a control signal by comparing the level of nitric oxide with a predefined threshold, and

the adjustment of the light dosage to treat damage in accordance with the controlling signal.

On the basis of the method according to the invention can more accurately and easily adjust the dosage of the treatment of damage with minimal side effects.

The invention also relates to a device for the implementation stage of the method, as set forth above.

Below is a detailed explanation and other aspects of the invention.

Description of the DRAWINGS

The above and other aspects and features of the present invention are better seen from the following detailed description, considered in conjunction with the accompanying drawings, in which:

Figure 1 presents a schematic diagram that illustrates a variant implementation of the method according to the invention;

Figure 2 presents a schematic diagram that illustrates the device according to the variant embodiment of the invention;

Figure 3 shows the device for the treatment of damage in accordance with one embodiment of the invention;

On fighta device for the treatment of damage in accordance with another embodiment of the invention.

The same item numbers are used to designate identical parts in all the figures.

DETAILED DESCRIPTION

Figure 1 presents a schematic diagram illustrating a variant of the method according to the invention. The way of control over the treatment process damage includes the following stages:

- 11 monitoring the level of nitric oxide damage,

- generation of 12 control signal by comparing the level of nitric oxide with a predefined threshold, and

- adjustment of the 13 light dosage to treat damage in accordance with the controlling signal.

Light for the treatment of damage can be a monochromatic infrared light with a wavelength of 890 nm. When light hits the surface damage, the light is absorbed inside the blood vessels and stimulates the formation of nitric oxide in the injury site through healing path cNOS (constitutive isoform synthase nitric oxide). Nitric oxide is formed from the amino acid called L-Arginine by the enzyme synthase nitric oxide, and this enzyme has different isoforms. cNOS is a key regulator of homeostasis (regulation of blood flow). In the treatment of cNOS decreases the level of nitric oxide in the damaged spot. It is also well known that in the case of joint injury osteoarthritis PR is the treatment of cNOS reduced levels of nitric oxide.

Thus, nitric oxide, released from the injury site, is a reasonable indicator for objective evaluation of pain from damage. Significant relief of pain reached through intervention, based on the nitric oxide, without any unwanted side effects by increasing circulation, reducing irritation to the nerves and reduce inflammation in the joints. In physiological conditions, the nitric oxide reacts with oxyhemoglobin to form methemoglobin with a very high speed, so that the amount of methemoglobin in the place of damage is proportional to the amount of nitric oxide.

Control signal indicates an increase in the dosage of light (or light intensity), if the level of nitric oxide is higher than a predefined threshold; controlling signal indicates a reduction in the dosage of light, if the level of nitric oxide is lower than a predefined threshold.

Stage 11 is designed for:

- determine the level of methemoglobin,

- calculate the level of nitric oxide in accordance with a proportional relationship between the level of methemoglobin and the level of nitric oxide.

Nitric oxide binds with oxyhemoglobin, when dissolved in the blood. Nitric oxide and oxyhemoglobin in the blood is converted into methemoglobin. The most important reactions of oxide isocaproate involving iron hemoprotein and in particular, with the participation of oxyhemoglobin, which is converted to methemoglobin:

Hb(Fe2+)O2+NO→Hb(Fe3+)+NO3-where Hb(Fe3+is a methemoglobin.

In mammals, hemoglobin is quantitatively predominant hemosiderosis protein. The main function of hemoglobin is to associate, transfer and release of molecular oxygen. Iron associated with hemoglobin remains in the ferrous state (e.g., oxyhemoglobin) during binding, transfer and release of oxygen. When the iron associated with the hemoglobin is oxidized to ferric ion, trivalent iron ion is unable to carry oxygen. Oxidized hemoglobin is called methemoglobin.

In one embodiment, the implementation level of methemoglobin can be determined by: first, determine the magnetic fields generated by the transition from Fe2+in Fe3+and then you get level Fe3+in accordance with the magnetic field, and, finally, calculate the level of methemoglobin in accordance with the level of Fe3+.

Measurement of trivalent iron (Fe3+allows you to indirectly measure methemoglobin. In addition, the methemoglobin is proportional to nitric oxide, so the measurement of ferric allows you to measure nitric oxide as an indicator of what orrective light dosage for treatment of injuries.

It is known that iron is found in two main ionic States, which are called bivalent iron ion (Fe2+) and trivalent iron ion (Fe3+). Magnetism arises when there is imbalance in the structural arrangement of the ions. Divalent iron ion has a charge of plus two (+2); trivalent iron ion has a charge of plus three (+3). These two ions have different atomic radii, since the higher the charge trivalent iron ions closer attracts the electrons surrounding the ion, which can lead to the displacement of electrons from divalent iron ions to the more positively charged trivalent iron ions and create a weak magnetic field. The proposed variant embodiment of the invention measures the magnetic field (also called magnetic flux density, measured in Tesla is the unit of the SI).

In another embodiment, the level of methemoglobin can be determined by:

first, the lighting surface (tissue) near the damage. The surface can be special lighting source detecting light to determine methemoglobin, and a special source detecting light different from the light source to cure the damage.

The surface can be lit by one light source for treatment of injuries. the example for lighting the surface near the damage you can use a light source with a wide range, such as block lamps with high reflectivity Welch Allyn (position 7103-001).

Secondly, obtaining a spectrum of light reflected from the surface. Oxyhemoglobin has absorption spectra with peaks 542 nm and 580 nm, while methemoglobin has an absorption spectrum with a peak at 630 nm. When nitric oxide is released from the bound form, in order to diffuse inside the surrounding damage, shift the peaks of the absorption spectrum with 630 nm on 542/580 nm. Reflected from the surface of the light can be collected by using fiber optic cables to make microspectrometer, sensitive to light in the wavelength range (500-700 nm).

Thirdly, analysis of the correlation between the level of methemoglobin and oxyhemoglobin in accordance with the spectrum.

And, finally, calculate the level of methemoglobin on the basis of the relationship between the level of methemoglobin and oxyhemoglobin.

In an additional embodiment, the level of methemoglobin can be determined by the monitoring unit 21, which is configured to:

first, lighting the surface near the damage. The surface can be used to illuminate a special light source, which is used for determination of methemoglobin and the specific history the nick of light, used for determining the difference between a light source for treatment of injuries. The surface also can be lit by the same light source, which is used to treat damage.

secondly, obtaining wavelength range of light reflected from the surface.

third, determine the current for the light reflected from the surface, by converting the light reflected from the surface current. This can be done by several photodiodes. Pre-specified that the photodiodes are sensitive to the three peaks 542 nm, 580 nm and 630 nm.

fourthly, the analysis of the correlation between the level of methemoglobin and oxyhemoglobin in accordance with current. It is established that the oxyhemoglobin has peaks 542 nm and 580 nm, and the intensity of oxyhemoglobin compared with peak methemoglobin at 630 nm. Then calculate the ratio of peaks and compared with a predefined model.

And, finally, calculate the level of methemoglobin on the basis of the relationship between the level of methemoglobin and oxyhemoglobin.

Figure 2 presents a schematic diagram illustrating a device according to the variant embodiment of the invention. Device for controlling the treatment process damage contains:

the monitoring unit 21 for monitoring the level of nitric oxide damage,

the block is enerali 22 for generating a control signal by comparing the level of nitric oxide with a pre-defined threshold, and

block adjustment 23 to adjust the dosage of light to treat damage in accordance with the controlling signal.

Moreover, the monitoring unit is configured to determine a magnetic field, the receiving level of Fe3+the calculation of the level of methemoglobin in accordance with the level of Fe3+.

Light for the treatment of damage can be a monochromatic infrared light with a wavelength of 890 nm. When light hits the surface damage, the light absorbed by the blood and stimulates the formation of nitric oxide in the joints through the healing path cNOS.

Thus, the nitric oxide released from damages is a reasonable indicator for the objective assessment of pain damage. Significant relief of pain reached through intervention, based on the nitric oxide, without any unwanted side effects by increasing circulation, reducing irritation to the nerves and reduce inflammation in the joints.

Control signal indicates an increase in dosage, if the level of nitric oxide is higher than a predefined threshold; controlling signal indicates a reduction in the dose, if the level of nitric oxide is lower than a predefined threshold.

The monitoring unit 21 is intended for information marked as IF in figure 2, and for monitori the ha level of nitric oxide in accordance with the received information. Information may contain information about the magnetic field, spectral information, etc. Block adjustment 23, designed to give an adjusted dosage of light, denoted by AD figure 2.

The monitoring unit 21 is designed for:

determine the level of methemoglobin and

calculate the level of nitric oxide in accordance with a proportional relationship between the level of methemoglobin and the level of nitric oxide.

As well as the monitoring unit is arranged to illuminate the surface, obtaining a spectrum analysis of the ratio in accordance with the spectrum, calculate the level of methemoglobin on the basis of the relationship between the level of methemoglobin and oxyhemoglobin.

Under physiological conditions, the nitric oxide reacts with oxyhemoglobin, forming methemoglobin with a very high speed, and therefore the methemoglobin is proportional to the nitric oxide.

Nitric oxide binds with oxyhemoglobin, when dissolved in the blood. Nitric oxide and oxyhemoglobin in the blood is converted into methemoglobin. The most important reactions of nitric oxide flow involving iron hemoprotein and, in particular, with the participation of oxyhemoglobin, which is converted to methemoglobin:

Hb(Fe2+)O2+NO→b(Fe3+)+NO3-where Hb(Fe3+is a methemoglobin.

The mammalian what were the hemoglobin is quantitatively predominant hemosiderosis protein. The main function of hemoglobin is to associate, transfer and release of molecular oxygen. Iron associated with hemoglobin remains in the ferrous state (e.g., oxyhemoglobin) during binding, transfer and release of oxygen. When the iron associated with the hemoglobin is oxidized to ferric ion, trivalent iron ion is unable to carry oxygen. Oxidized hemoglobin is called methemoglobin.

In one embodiment, the implementation of the monitoring unit 21 can determine the level of methemoglobin by: determining the magnetic field generated due to a shift of Fe2+in Fe3+, then a receiving level of Fe3+in accordance with the magnetic field, and, finally, calculate the level of methemoglobin in accordance with the level of Fe3+.

Measurement of trivalent iron (Fe3+allows you to indirectly measure methemoglobin. In addition, the methemoglobin is proportional to nitric oxide, so the measurement of ferric allows you to measure nitric oxide as an indicator of adjusting the dosage of light to treat the damage.

It is known that iron is found in two main ionic States, which are called bivalent iron ion (Fe2+) and trivalent iron ion (Fe3+). Magnetism arises when there is the Nar is seeking balance in the structural arrangement of the ions. Divalent iron ion has a charge of plus two (+2); trivalent iron ion has a charge of plus three (+3). These two ions have different atomic radii, since the higher the charge trivalent iron ions closer attracts the electrons surrounding the ion, which can lead to the displacement of electrons from divalent iron ions to the more positively charged trivalent iron ions and create a weak magnetic field. The proposed variant embodiment of the invention measures the magnetic field (also called magnetic flux density, measured in Tesla is the unit of the SI).

In another embodiment, the monitoring unit 21 can be designed to determine the level of methemoglobin by:

lighting surface (tissue) near the damage. The surface can be special lighting source, which is used for determination of methemoglobin, and a specific light source for definition differs from the light source for the treatment of damage. The surface also can be lit by the same light source, which is used to treat damage. For example, for illumination of the surface near the damage you can use a light source with a wide range, such as block lamps with high reflectivity Welch Allyn (position 7103-001);

get spec is RA light, reflected from the surface. Oxyhemoglobin has absorption spectra with peaks 542 nm and 580 nm, while methemoglobin has an absorption spectrum with a peak at 630 nm. When nitric oxide is released from the bound form, in order to diffuse inside the surrounding damage, shift the peaks of the absorption spectrum with 630 nm on 542/580 nm. Reflected from the surface of the light can be collected by using fiber optic cables to make microspectrometer, sensitive to light in the wavelength range (500-700 nm);

the analysis of the correlation between the level of methemoglobin and oxyhemoglobin in accordance with the spectrum;

calculate the level of methemoglobin on the basis of the relationship between the level of methemoglobin and oxyhemoglobin;

In an additional embodiment, the monitoring unit 21 can be further designed to determine the methemoglobin by:

lighting the surface near the damage. The surface can be used to illuminate a special light source, which is used for determination of methemoglobin, and a specific light source used for determining the difference between a light source for treatment of injuries. The surface also can be lit by the same light source, which is used to treat injuries;

receiving the wavelength range of light reflected from p the surface;

determine the current for the light reflected from the surface, by converting the light reflected from the surface current. This can be done by several photodiodes. Pre-specified that the photodiodes are sensitive to the three peaks 542 nm, 580 nm and 630 nm;

the analysis of the correlation between the level of methemoglobin and oxyhemoglobin in accordance with current. It is established that the oxyhemoglobin has peaks 542 nm and 580 nm, and the intensity of oxyhemoglobin compared with peak methemoglobin at 630 nm. Then calculate the ratio of peaks and compared with a predefined model:

calculate the level of methemoglobin on the basis of the relationship between the level of methemoglobin and oxyhemoglobin.

Figure 3 shows the device for the treatment of damage in accordance with one embodiment of the invention. therapeutic device 30 includes multiple light sources 31 and the device 20 (not shown in figure 3). The device 20 includes a monitoring unit 21, the generating block 22 and block adjustment 23. In one of the embodiments of the invention the monitoring unit 21 can also contain several sensors 32 located along with several light sources 31.

The light source 31 may be a DM (light emitting diode) for emitting light p is harming for therapeutic purposes. The monitoring unit 21 is used for monitoring the level of nitric oxide damage in order to adjust the dosage of light. Block adjustment 23 is designed to adjust the dosage of light therapy by adjusting the total light intensity, for example, by on/off one or more light sources, adjust the intensity of the one or more light sources or adjustment of the intensities of all light sources, in accordance with the controlling signal generating block 22.

The sensors 32 are used to gather information about the damage to the monitoring unit 21.

The light sources 31 and the sensor 32 is located on the base (not labeled). The Foundation has the flexibility to be adjusted to any part of the body. The patient can use the device to treat damage 30 at home or at work, and without the intervention of an expert. The device 20 may include one or more CPUs (Central processor) and/or control circuits, in order to adjust the dosage of the light emitted by the light sources 31. The light sources 31 are powered by electroplating or other elements.

4 shows the device for the treatment of damage in accordance with another embodiment of the invention. Figure 4 (A) shows the layout of the Board and permineralization sensors in the device; figure 4 (B) shows the measurement of the magnetic field of each supermarketization sensor; figure 4 (C) shows the combination of the magnetic fields from all supermagnetosonic sensors.

therapeutic device 30 includes multiple light sources 31 and the device 20 (not shown in figure 3). The device 20 includes a monitoring unit 21, the generating block 22 and block adjustment 23. In one of the embodiments of the invention the monitoring unit 21 can also contain several sensors 32 located along with several light sources 31.

The sensors 32 are supermarketization (GMR) sensors to detect magnetic fields. Supermarketization sensors are more sensitive than Hall sensors. The sensors 32 are composed of arrays of three-on-three. Analog multiplexer (not shown in figure 4) can be used to select signals from nine sensors 32 for further shaping, amplification and analog-to-digital signal conversion.

The light sources 31 can emit light in the infrared range of approximately 890 nm.

Before treatment damage to the device 20 calculates the initial magnetic field (Bin); after the start of treatment to monitor the level of nitric oxide, the device 20 periodically calculates the magnetic field (Bcur), and Bcurabove Inin.

where i takes values from 1 to n, i denotes the number supermagnetosonic sensors.

It should be noted that the above embodiments of illustrate and not limit the present invention, and that the experts in this field will be able to develop alternative implementation, without going beyond the scope of the attached claims. In the claims, any reference in brackets should not be construed as limiting the claims. The word "contains" does not exclude the presence of elements or stages that are not listed in the claim or in the description. The presence of an element in the singular does not exclude the presence of several such elements. The present invention can be realized by a hardware block that contains several separate elements, and the unit is programmed computer. The claims related to the device enumerates several blocks some of these blocks can be realized in one and the same item of hardware or software. The use of the words "first", "second", "third" and so on does not denote any order. These words should be interpreted as a name.

1. Device for controlling the treatment process damage, which includes:
the monitoring unit 21) for monitoring the level of nitric oxide damage,
the generation unit (22) for generating a control signal by comparing the level of nitric oxide with a predefined threshold and
block adjustment (23) to adjust the dosage of light to treat damage in accordance with the controlling signal, where the monitoring unit (21) is designed for:
determine the magnetic fields generated by the transition from Fe2+in Fe3+,
get the level of Fe3+in accordance with the magnetic field,
calculate the level of methemoglobin in accordance with the level of Fe3+and
calculate the level of nitric oxide in accordance with a proportional relationship between the level of methemoglobin and the level of nitric oxide.

2. The device (20) according to claim 1, where the monitoring unit (21) is designed for:
lighting the surface near the damage,
obtain a spectrum of light reflected from the surface,
the analysis of the correlation between the level of methemoglobin and oxyhemoglobin in accordance with the spectrum, and
calculate the level of methemoglobin on the basis of the relationship between the level of methemoglobin and oxyhemoglobin.

3. The device (20) according to claim 1, where the monitoring unit (21) is additionally suitable for:
lighting the surface near the damage,
receiving the wavelength range of light reflected from the surface,
determine the current for the light, reflected the frame from the surface, by converting light reflected from the surface, in the current
the analysis of the correlation between the level of methemoglobin and oxyhemoglobin in accordance with the current, and
calculate the level of methemoglobin on the basis of the relationship between the level of methemoglobin and oxyhemoglobin.

4. The device (20) according to claim 1, where the control signal indicates an increase in dosage, if the level of nitric oxide is higher than a predefined threshold; controlling signal indicates a reduction in the dose, if the level of nitric oxide is lower than a predefined threshold.

5. Device for treating injury (30), containing multiple light sources (31)emitting therapeutic light to damage, and the device (20) to control the dosage of light from light sources (31), where the device (20) includes:
the monitoring unit (21) for monitoring the level of nitric oxide damage,
the generation unit (22) for generating a control signal by comparing the level of nitric oxide with a predefined threshold, and
block adjustment (23) to adjust the dosage of light to treat damage in accordance with the controlling signal, where the monitoring unit (21) is designed for:
determine the magnetic fields generated by the transition from Fe2+in Fe3+,
get the level of Fe 3+in accordance with the magnetic field,
calculate the level of methemoglobin in accordance with the level of Fe3+and
calculate the level of nitric oxide in accordance with a proportional relationship between the level of methemoglobin and the level of nitric oxide.

6. Device for treating injury (30) according to claim 5, where the monitoring unit (21) contains several sensors (32), located on the ground along with several light sources (31), to collect information from damage, and information contains information about the magnetic field or spectral information.

7. Device for treating injury (30) according to claim 6, where the sensor (32) are supermarketization sensors.



 

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2 dwg

FIELD: medicine.

SUBSTANCE: treating tuberculous spastic microcystis with underlying anti-tuberculosis chemotherapy requires peridural anaesthesia 5-7 days long. That is combined with the exposure to a laser light at a wave length of 632 nm of power 12 mW covering a biologically active point of the urinary bladder on a hand. The 4-minute exposure is daily for 5-7 days.

EFFECT: higher clinical effectiveness by the fast reduction of pain syndrome, higher urinary bladder capacity, avoiding the need of surgical intervention and disability.

1 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine and concerns a device for the infrared exposure on the human skin. The device is presented in the form of a magnetic resonance tomographic scanner and comprises a receive/transmit channel, a three-dimensional localisation unit, a microprocessor controller and a display. The device is also provided with a local exposure unit presented in the form of a manipulator with an IR laser, a lens and a marker for laser beam binding to a coordinate system of the analysed area.

EFFECT: higher accuracy and intensity of the local exposure, as well as providing object tissue change tracking.

3 cl, 1 dwg

FIELD: medicine.

SUBSTANCE: treating a wound surface with dioxidine is followed by an infrared laser light with a permanent magnetic field not earlier than 5 days after the operation. Magnetic induction intensity is within the range of 20-50 mT; a laser pulse repetition frequency is within the range of 80 Hz, and a power is 0.25-0.5 W. The whole postoperative area is subject to the daily distant labile exposure to a defocused beam at 0.5 cm for 30-60 seconds. That is followed by applying tissues with hypertonic solution 3 to 5 times a day; the therapeutic course is 10-15 procedures.

EFFECT: method enables providing higher effectiveness and reducing a length of treatment ensured by the integrated exposure to the antibacterial agents and magnetic laserophoresis in the presented regimen, preventing developing postoperative complications.

2 ex

FIELD: medicine.

SUBSTANCE: endodontic treatment stage involving retrieval and dilation of a root canal is performed. Gluftored liquid is introduced into the root canal of the tooth. A fibre cable is placed above a tooth canal orifice, and the liquid is reflected by means of a laser light for 30-60 seconds. The root canal is dried with a paper point. Pre-shaken Gluftored suspension is introduced into the root canal. The fibre cable is placed above the tooth canal orifice, and the suspension is reflected by means of the laser light for 30-60 seconds. The root canal is dried and filled.

EFFECT: method provides higher clinical effectiveness in the patients with dental pulp and periodontal diseases by activating the course of chemical reactions in mineralising liquid and suspension, crystal obturation of dentine tubes and closing a microbial invasion propagation path into the periodont to be protected against toxins and tissue disintegration products, forming a single mineral complex of the liquid, suspension and dentine of the root canal of the tooth, photobiostimulation of periodontal microcirculation by means of low intensity laser light energy, the presence of copper ions provides the permanent bactericidal effect.

10 dwg, 1 ex

FIELD: medicine.

SUBSTANCE: light therapy with red-infrared radiation from the apparatus "Geska-1" is carried out. A wavelength of red radiation is 660-675 nm, and the total density of radiation power is not less than 4 mW/cm2. A wavelength of infrared radiation is 840-950 nm, and the total density of radiation power is not less than 15 mW/cm2. An area of irradiation of an emitter is 4 cm2. An impact is performed on the back and sole areas of feet for 2-4 minutes on each area, on the area of the popliteal fossa for 2-4 minutes on each extremity, on the area of the spine at the level of segments L2-L4 paravertebrally from two sides for 2-4 minutes from each side. An impact on feet is performed daily; an impact on the popliteal fossa area and the area of the spine is alternated every other day. The total time for a procedure constitutes 12-24 minutes, daily, with a course of 10 procedures.

EFFECT: method makes it possible to reduce the expression of neurological symptomatic and pain syndrome, compensate the hydrocarbon exchange, increase general adaptation abilities of the organism due to anti-inflammatory, anaesthetic and wound-healing action, apply the claimed method in the patients with contraindications to laser therapy, as well as in decompensation of diabetes mellitus.

2 ex

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular to dentistry, and can be used for treatment of destructive forms of chronic periodontites of single-rooted and multi-rooted teeth. An access to the area of periodontitis is formed. Laser irradiation is carried out by passing the laser lightguide into the periapical space to the area of periodontitis in a pulse-periodic mode. The wavelength is 980 nm, irradiation is carried out for 30-60 s with reciprocating movements of the lightguide and laser radiation power 0.5-0.9 W. After 3-5 days additional irradiation of the periapical space of the periodontitis area by radiation of a low-intensity laser with the wavelength 66 nm, power 200 mW is performed also in a pulse-periodic mode for 2 min.

EFFECT: method makes it possible to accelerate regeneration of the bone tissue due to expressed anti-inflammatory, bacteriostatic, bactericidal and reparation-stimulating effects, stable remission is achieved due to local immunomodulating impact, reduction of destructive changes in the periapical tissues, increase of density and homogeneity of the bone tissue.

6 dwg, 3 ex

FIELD: medicine.

SUBSTANCE: for complex therapy of the first time identified pulmonary tuberculosis traditional anti-tuberculosis therapy is carried out. After two weeks of anti-tuberculosis chemotherapy, complex physiotherapy is performed. In the morning 40-60 minutes after meal ultrasound inhalation with an inhibitor of proteases contrykal in a dose of 5000 UNITS, diluted in 3-4 ml of an isotonic solution of sodium chloride is carried out. Inhalation is carried out at a temperature of the solution of 35°C for 10 minutes on the apparatus "Vulkan-1". 20 minutes after inhalation magnetic infrared laser therapy (MIL-therapy) is performed from the apparatus "Rikta-04/4" on affected zones of the lungs by contact method of the application of the apparatus emitter. Frequency of the laser impact constitutes 5-50 Hz. Average power of infrared light-diode radiation is 60±30 mW, an impact with constant magnetic field is realised with induction 35±10 mT for 1-5 min. The course of treatment constitutes 30-40 daily procedures as well.

EFFECT: enhancement of infiltration resorption, closing decay cavities in the shorter period, arrest of intoxication symptoms by the end of the first month of treatment, reduction of terms of elimination of clinical and laboratory manifestations of tuberculosis.

3 cl, 2 ex

FIELD: medicine.

SUBSTANCE: invention can be used in treating patients with Reinke oedema. The Lumenis SHARPLAN 30C CO2 laser with the Acuspot-712 adapter having a power of 1-1.5 W in a superpulse mode is used to make an incision of a mucous membrane of the upper vocal fold along a free end throughout the oedema. An electric suction machine is used to remove mucous exudate from a submucosal space. The mucous membrane is placed back, modelled for the defect closure and fixed to substructures with the Hemo-Compact glue. The glue is applied on a proper plate of the vocal fold.

EFFECT: method enables achieving the near-normal shape of the vocal folds, minimising a risk of coarse scar tissue formation, providing the best fixation of the mucous membrane.

2 cl, 1 ex

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