Ointment for burns, folliculitis, furunculosis, vasculitis treatment and wound healing

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to the pharmaceutical industry, namely to an ointment for burns, folliculitis, furunculosis, vasculitis treatment and wound healing. The ointment for burns, folliculitis, furunculosis, vasculitis treatment and wound healing containing: bees wax, line seed oil, kerosene and visceral fat of pig taken in certain proportions.

EFFECT: ointment possesses a biostimulating effect, reduces the wound healing time with no post-therapeutic cicatrisation with good fixation, uniform distribution on the skin surface and ease of use.

9 dwg, 9 ex

 

The invention relates to the field of medicine and pharmacy and applies ointment for external use for the treatment of burns, folliculitis, furunculosis, vasculitis, and the healing of postoperative and post-traumatic other wounds (cut, puncture, fire), which can find application in medicine and cosmetology. The use of this ointment promotes full recovery of the skin, accelerates wound healing without scar formation after treatment.

Known ointment "Benin" for the treatment of purulent and infected wounds of various etiologies, including fir oil, propolis, pine resin, spermaceti and the fat penguin with a mass ratio of components 3-7:0,5-1,5:0,5-1,5:1,5-2,5:7-15, respectively (patent RF №2058776, IPC6AC 9/06, publ. 27.04.96).

A disadvantage of the known ointment is the presence in the formulation known spermaceti ointment and fat penguin, accessibility and raw materials are limited.

Known ointment "Zwar" for the treatment of purulent and infected wounds of various etiologies, containing the following components, wt.%: pine resin (the resin of pine or spruce) - 7,0-8,0; beeswax - 6,7-7,3; butter - 6,5-7,5; vegetable oil - 6,5-7,5; fat interior (pork, or beef, or goose, or sheep) - 19,0-22,0; propolis - 0,5-1,0; bow-turnip - rest (RF patent N 2139708, IPC 6 AC 9/06, publ. 20.10.99).

The disadvantages of the local ointments are insufficient range of therapeutic actions and presence in the recipe inaccessible components.

Known ointment for the treatment of inflammatory and traumatic diseases of the musculoskeletal system and peripheral nervous system, containing the oleoresin of pine or fir, beeswax, propolis and vegetable oil, mummy, fir oil and sea buckthorn oil in the following ratio, wt.%: the oleoresin of pine or fir - 5,0-15,0; beeswax - 5,0-15,0; propolis - 1,0-3,0; mummy - 0.1 to 0.3; oil fir - 1,0-4,0; sea buckthorn oil - 1,0-5,0; vegetable oil - the rest (RF Patent No. 2190389, IPC7AC 9/06, publ. 10.10.2002).

The disadvantages of the known ointments are insufficient spectrum of therapeutic action, as well as limited access to some components. Known composition does not allow to maintain a high quality of ointment for a long time, and inconvenient to use due to poor fixation and uneven distribution on the skin surface.

Closest to the proposed technical solution is the ointment for the treatment of burns, skin diseases and wound healing containing the resin, beeswax, sea buckthorn oil, butter, lard, and a biologically active substance selected from the group of: aloe extract, plantain extract, extract of Bidens, rosehip extract, St. John's wort oil, linseed oil, calendula oil, burdock oil, chamomile oil or propolis (RF Patent No. 2325175, IPC13AC 9/06, AK 35/64 OR 17/02, publ. 27.05.2011).

A disadvantage of the known ointment is the presence in the formulation known ointments components, the availability and source of raw materials is limited, and known composition does not allow to maintain a high quality of ointment for a long time.

Technical result improved anti-inflammatory and regenerating action.

The technical solution is that the ointment for the treatment of burns, folliculitis, furunculosis, vasculitis, and wound healing containing beeswax, linseed oil, lard, characterized in that the composition of ointments include internal lard, and kerosene, in the following ratio, wt.%:

Beeswax8,0-10,0
Flaxseed oil18,0-20,0
Kerosene4,0-5,0
Internal lardRest

Quantitative intervals of the ratio of components included in the composition of ointments, were determined experimentally, are optimal to ensure maximum effectiveness of the ointment. Deviation from the proposed ratio of components is impractical, as it reduces treatment efficiency is.

Thus, the content of beeswax should be in the range of 10 wt.%. The increase of its content in excess of 10 wt.% and reduction of less than 8 wt.% leads to deterioration of ductility ointments, resulting in the inconvenience of using ointments.

The decrease in the amount of linseed oil below 15.0 wt.% reduce the effectiveness of this component in the composition of ointments, and increasing amounts of linseed oil more than 20 wt.% results ointment liquid consistency, spreading over the surface of the skin, which also leads to the inconvenience of using ointments.

The components of the ointment each separately have a healing effect on the skin.

Domestic pork fat (Adeps suilus enteris) on fatty acid composition (%/m) contains saturated acids: myristic 0,8-0,9, palmitic 27-30, stearic 13-18; unsaturated acid: 9-hexadecanoyl 1.7 to 1.9, oleic 37-44, linoleic 8-9, arachidonic acid 2% and linolenic 2%. Domestic pork fat has a calming and moisturizing the skin effect, in addition, it has long been used as a remedy for burns. Unlike the prototype in the composition of ointments impose domestic pork fat, i.e. fat, selected from the great and the lesser omentum pigs (internal)rather than subcutaneous fat.

Beeswax (Cera flava) promotes the healing of wounds and fractures, nourishes and strengthens the skin. The wax according to the chemical nature of lizok fats. In the composition of the wax are available alcohols and fatty acids, as well as large amounts of vitamin A. the presence of the wax carotene and vitamin a makes it useful in the treatment of many skin diseases, retards the growth of some pathogens, has antibiotic action. In ointments beeswax facilitates the formation of emulsions and increases its stability, and due to its nature improves absorbing their properties (I.E. Iirish. Bees and medicine. - "Medicine". - Tashkent. - 1975. - 279 S.).

Kerosene (eng. kerosene, from GK. keros - wax), a mixture of hydrocarbons advantages. C9-C16(boil within 110-320°C). Contain impurities of sulfur, nitrogen or oxygen compounds. Color varies from colorless to light brown with a bluish tint. It consists of: limiting aliphatic hydrocarbons 20-60%, naphthenic 20-50%, bicyclic aromatic 5-25%, of unsaturated to 2%. The kerosene used in the treatment of skin diseases. Along with these kerosene was and is a wonderful disinfectant, which, however, should be used with caution (minimum dose), remembering that it is still a technical matter.

Flaxseed oil (Linum usitatissimum L.). Crude oil contains vitamins F (46%), a, E, minerals, and the richest collection of fatty acids: up to 70% triglycerides, linoleic and alpha-Lin is lenovos acids. Palmitic 5.0% Stearic 1.6% Oleic 20.9% Linoleic 16.5% Linolenic 55.8% Arachidic 0.1% Eicosenic 0.1%, due to what has epithelizing effect, promotes the healing of wounds, cracks on hands and feet, resorption of scars, is used in thermal and chemical burns, frostbite and radiation skin lesions, as well as for treatment of various skin diseases: eczema, dermatitis, psoriasis. It also has analgesic, antiseptic, antioxidant, capillaries firming properties.

In the proposed fatty ointment base, for example, softens inflammation, beeswax, kerosene and linseed oil to give a therapeutic effect, helping to accelerate the healing process, a common set of components prevents the formation of scars, fully restoring the skin.

Although individual components of the ointment, or a combination found in known therapeutic ointments such purpose, the claimed combination of ingredients and their ratio in the composition of ointments were not found. The inventive combination of the components, taken in experimentally selected, the optimal amount that achieves the claimed therapeutic effect. Other ratios taken components are not allow in the short term to achieve the desired therapeutic effect.

The invention is illustrated by the following specific examples will is of high value.

Example 1. Preparation of ointment

Heated to a liquid state and strained domestic pork fat (650 g) and beeswax (100 g) are thoroughly mixed and heated to 120-130°C. the mixture is Then cooled to 70°C. and mixed with linseed oil (200 ml) and kerosene (50 ml). After stirring until a homogeneous mass is obtained ointment when hot pour in the prepared container. The ointment is a homogeneous thick viscous paste with a characteristic odor. The ointment is non-toxic. The melting point of the obtained ointment - 50°C. the Ointment should be stored in dark, cool place at a temperature of storage - 0-15°C, protected from direct sunlight. Shelf life - 1 year without loss of original activity.

The ointment is applied on the skin or on sterile namalenie napkins in the form of compresses, depending on the extent of damage. When applied to an open wound or burn the claimed ointment allows you to remove the dressing without damaging fragile epithelium, while changing the dressing is carried out until complete epithelialization.

In case of thermal burns, abrasions, post-operative, gunshot and other wounds and lesions ointment applied topically in the form of ointment bandages 1-2 times daily in a dose of 10-50 g (depending on the area affected) in the treatment 7-21 days.

When the vasculitis of the claimed ointment applied to the affected skin 2-3 RA is a day in a thin layer, rubbing her fingertips with gentle circular movements.

For dry skin, deep and painful fractures of the hands and feet of the claimed ointment applied 3-4 times per day.

Contraindications to the use of a idiosyncrasy.

Example 2. Sick Days - 3 years. Thermal burns 3rd degree largest about 30% of the body surface. For treatment was assigned ointment. To the burn superimposed ointment bandage 2 times a day. Signs of inflammation (swelling, flushing, hyperthermia) significantly decreased on the third day of using ointments. On the seventeenth day of treatment at the burn was formed smooth pink skin. Complete healing occurred after 25 days of treatment. On the burn scars and ties remained. The patient is now 44 years with two adult children.

Example 3. Patient S - 32, Filed a complaint on long nonhealing wounds, was observed redness of the skin with edema and infiltration with purulent offices. The claimed ointment was applied to the wound 2 times a day, and at night were imposed in the form of an ointment dressing. On the fourth day hyperemia and edema slept, the wound was cleansed from pus, infiltration decreased. On the fifth day began epithelialization and after nine days the wound healed without scarring.

Example 4. Patient A., age 16. Diagnosis: tinea chin and face (Photo 1). Increasing the temperature. There are pustules in size from 2 to 5 mm in diameter with a pink-red inflammatory rim; small pain. The ointment was applied to the affected skin 2 times a day. On the 3rd day was observed drying the contents of pustules in a brown crust, after exclusion of which remained slight pigmentation and peeling (Photo 2).

The fifth day of symptoms folliculitis fully cropped. It was recommended to continue the procedure lubrication with a frequency of 1-2 times per day. On 8-9th day of the manifestation of folliculitis and related symptoms completely resolved. The patient was in good condition.

Example 5. Patient L., 31. Applied thermal burn 2-3 degrees. The ointment was applied to the affected skin 2 times a day. Already at day 4 showed a significant improvement of the skin condition. The duration of treatment was 14 days. When examining a patient on the 14th day of the treatment was that the condition was considerably improved, skin itching does not bother, restore skin elasticity.

Example 6. Patient K., aged 40 applied with thermal burns 2-3 degrees, the explosion of the tank burns on the face, neck, chest, shoulders. To the burn superimposed ointment dressing 1 every day. Inflammation has stopped on the sixth day of application of the ointment. On the fifteenth day of treatment at the burn was formed rovnyagina. Complete healing occurred after 17 days of treatment. On the burn scars and couplers were observed.

Example 7. Patient F., 36 years old with thermal 2-3 degree burns, scalding with boiling syrup to the right anterior-lateral, left anterior-medial surface of the thigh (photo 3). To the burn superimposed ointment dressing 1 every day. Inflammation has stopped for 3-4 day application of ointments (photo 4). 10-12 day most of the burn surface was covered with smooth skin (photo 5). Complete healing occurred on day 16. On the burn scars and ties remained, but some time was observed hyperemia (photo 5). After another 2 weeks gone and hyperemic spots (photo 6).

Example 8. Patient D., 11 years old, diagnosed with vasculitis. Observed swelling and redness of the skin with edema and infiltration with purulent branches (photo 7). In addition to the main treatment used, we offer ointment. The ointment was applied to the affected skin 2 times a day. On the 5th day was observed drying the contents of pustules in a brown crust (photo 8), after exclusion of which remained pale pigmentation (photo 9).

Example 9. Patient D., 28 years old, the diagnosis of furunculosis. Observed swelling and redness of the skin with edema and infiltration with purulent offices. The boils were overlapped ointment bandage 2 times a day. Inflammation has stopped for 3-4 day PR is the changes in the ointment. On the 6th day was observed drying content boils in a brown crust, after exclusion which remained pale pigmentation.

Treatment of the claimed ointment in almost all cases took place with positive results in the treatment of burns, skin diseases and the healing of other wounds, without complications and side effects. Application of ointments showed its activating effect on the regenerative processes of the connective tissue and epithelium, indicating a biostimulating effect of ointments and confirmed by the shortening of the healing without the formation of scars after treatment, with good fixation and a uniform distribution on the skin surface and ease of use.

Ointment for the treatment of burns, folliculitis, furunculosis, vasculitis, and wound healing containing beeswax, linseed oil, lard, characterized in that the composition of ointments include internal lard, and kerosene, in the following ratio, wt.%:

Beeswax8,0-10,0
Flaxseed oil18,0-20,0
Kerosene4,0-5,0
Internal lardRest



 

Same patents:

FIELD: medicine.

SUBSTANCE: experimental wound is cleaned daily, first with normal saline (NaCl), and then coated with modified montmorillonite clay containing 0.1 to 4.35 wt % of silver. The preparation is introduced into the wound in an amount of 0.1 g per a wound of 1.5 cm in diameter.

EFFECT: higher rate of septic wound healing.

3 tbl, 3 dwg

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine, namely to cosmetology, and can be used for treatment of skin aging. For this purpose, used is a medication, which contains a basic fibroblast growth factor (bFGF) as a single active ingredient, which is introduced intracutaneously or subcutaneously into the place of a scar or into the surrounding region, for instance, a keloid, a hypertrophic scar and a scar contracture; in addition, the medication is also intended for treatment of one or more types of skin aging, selected from the following list: skin wrinkles, sagging skin, rough skin, skin thinning and reduction of skin resilience and elasticity because of rupture of dermal tissues or reduction of functions of fibroblast cells, with skin aging being photoaging, and a value of a dose of the basic fibroblast growth factor (bFGF) constituting from 0.1 mcg to 1 mg per 1 cm2 of skin, which represents the treatment target.

EFFECT: inventions ensure significant reduction of wrinkles, improvement of the skin structure, as well as due to an increase of its turgor and an increase of the volume of the subcutaneous adipose cellular tissue.

6 cl, 4 ex, 10 dwg

FIELD: medicine.

SUBSTANCE: what is described is a dressing for treating skin conditions and relieving symptoms of skin conditions accompanying blood protein exudation, or for absorbing blood proteins transuding onto the skin.

EFFECT: using the dressing for clearance of waste proteins secreted onto the skin.

8 cl, 22 dwg, 7 ex

Burn ointment // 2523551

FIELD: medicine.

SUBSTANCE: ointment contains biologically active substances which are Apis mellifera in an amount of 21-23 wt %, St. John's wort oil in an amount of 12-14 wt %, propolis in an amount of 10-12 wt % and wax in an amount of 7-9 wt %, as well as Vaselin and lanolin as the ointment base.

EFFECT: invention accelerates cell regeneration processes considerably due to a synergetic action of the ingredients.

7 ex

FIELD: medicine.

SUBSTANCE: method involves coating a keratoma surface with a mixture of meadow saffron tincture 1 table spoon and Phellinus tuberculosus tincture 3-4 drops. The mixture is applied once a day on the keratoma and a skin area 1.5-2.0 mm from the keratoma border. The mixture is applied by a thin brush, first with a prime layer and with a second layer after drying.

EFFECT: minimally painful keratoma removal.

3 ex

FIELD: medicine.

SUBSTANCE: material consists of several layers: an inner layer is made from chitosan nanofibres/superfine fibres, and an outside layer are used as an electrical forming substrate and exercise the protective function. The chitosan layer is made from herbal or mixed herbal and animal chitosan and can contain antibiotic. The multilayer material can contain at least one more layer of biopolymer nanofibres/superfine fibres electroformed of cellulose diacetate or gelatin. The three-layer material with the chitosan layer of the nanofibres/superfine fibres is applicable for local wound and burn healing.

EFFECT: material resistance to mechanical stress.

15 cl, 4 dwg, 8 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely dermatology and may be used for stimulating repair of wounds of various geneses. For this purpose, wound cleansing is followed by daily dressings with dihydroquercetin powder applied on a wound surface at the bacterial content no more than 103-4 m.c. per 1 cm2 as a layer of 1-2 mm until wound self-epithelisation, before or after autodermoplasty with a free split-skin flap. That is combined with prescribing the biologically active additive Laviocard+ orally 1 capsule 2 times a day with food for 21 day.

EFFECT: method provides correcting abnormal lipid peroxidation and activating antioxidant protection in local and systemic homeostasis by stimulating and reducing a repair length.

2 ex, 6 tbl

FIELD: medicine.

SUBSTANCE: invention can be used for treating degree III-IV radiation injuries on radiation fields following neutron therapy in patients suffering from local recurrent breast cancer (BC). That is ensured by wound irrigation with ozonised distilled water with ozone concentration of 10,000 mcg/l; a skin ulcerous defect is processed in a vacuum container for 10-15 minutes with gaseous ozone with the concentration of 10,000 mcg/l. That is followed by ozonised air applications with the parameters of: peroxide number - 18%, acid number - 71 mg CFU/g on the skin ulcerous defect once or twice a day for 10-15 days every 5-7 days for 2-3 courses.

EFFECT: ulcer detersion from purulent deposits, active regeneration and the skin ulcerous defect healing.

6 dwg, 2 ex

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to medicine and may be used for treating an individual suffering from a persistent, sluggish, partially healing, open or chronic wound. That is ensured by administering anti-connexin 43 polynucleotide approximately 0.001 to approximately 1 mg/kg of body weight into the wound of the individual in a pharmaceutically acceptable carrier. Stimulating and improving wound healing, improving wound healing rate in a diabetic patient and an individual suffering from a chronic skin wound is also suggested. Kits and finished products containing Pluronic F-127 and anti-connexin 43 polynucleotide presented by SEQ ID NO: 1 for wound healing.

EFFECT: group of inventions provides wound healing, relieved inflammation within the persistent wound, as well as minimised cicatrisation.

129 cl, 4 dwg, 3 ex

FIELD: medicine, pharmaceutics.

SUBSTANCE: there are presented: using a compound of formula (1) or its salt for preparing a drug for increasing HIF-1α stabilisation in a cell, as well as for preparing a drug enhancing the immune response in an individual, for preventive management of a wound to avoid an infection, for treatment of the microbial infection, for improvement of efficacy of a vaccine for management of the wound in the individual. What is presented is a pharmaceutical composition containing the above HIF-1α prolyl hydroxylase inhibitor and one or more additives. What is shown is achieving the declared applications by using the new compound of formula (1) with the HIF-1α prolyl hydroxylase (HIFPH2 (EGLN1)) inhibitor. It makes it applicable for treating HIF-1 alpha activity related diseases, conditions and/or syndromes.

EFFECT: preparing the drug for increasing HIF-1α stabilisation in a cell.

26 cl, 20 dwg, 8 tbl, 13 ex

FIELD: medicine.

SUBSTANCE: invention relates to the application of a solid medicinal product, which is heated under the impact of an alternating magnetic field, for further therapeutic treatment after surgical ablation of tumours and cancerous ulcers. The medicinal product represents a surgical implant, presented in the form of a physiologically acceptable fabric, sponge or film. The medicinal product contains magnetic particles, which generate heat when excited by an impact of the alternating magnetic field, and in this way, heat the medicinal product.

EFFECT: invention ensures considerable improvement of further treatment after operation on cancerous tumour in comparison with chemotherapy.

21 cl, 14 ex

FIELD: veterinary medicine.

SUBSTANCE: method of preparing the anti-inflammatory veterinary ointment for outward application consists in mixing while heating to the temperature of 40-50°C in the reactor of molten petrolatum, pine oleoresin, chlorophyll-carotene paste until homogenous consistency, then glycerine and olive oil is fed portionwise with continuous stirring, after which again mixing of the components is carried out for 10-30 minutes until the homogeneous mass, the resulting ointment is cooled and packaged, at that the components of the mixture are taken in the following ratio, wt %: pine oleoresin 3.0; chlorophyll-carotene paste 3.0; petrolatum 69.0; glycerine 5.0; olive oil 20.0.

EFFECT: improved efficacy of treatment.

2 ex

FIELD: medicine.

SUBSTANCE: drug preparation for treating tuberculosis contains an active substance isoniaside, and a pharmaceutical carrier tiozol gel with the isoniaside concentration of 5.7-54.5 wt % and the tiozol gel concentration of 45.5-94.3 wt %.

EFFECT: higher clinical effectiveness in tuberculosis and lower toxicity.

2 cl, 2 tbl

Burn ointment // 2523551

FIELD: medicine.

SUBSTANCE: ointment contains biologically active substances which are Apis mellifera in an amount of 21-23 wt %, St. John's wort oil in an amount of 12-14 wt %, propolis in an amount of 10-12 wt % and wax in an amount of 7-9 wt %, as well as Vaselin and lanolin as the ointment base.

EFFECT: invention accelerates cell regeneration processes considerably due to a synergetic action of the ingredients.

7 ex

FIELD: medicine.

SUBSTANCE: pharmaceutical composition can additionally contain ethylenediaminotetraacetic acid, polyvinyl pyrrolidone, polyvinyl alcohol, a preserving agent specified in a group: Nipagin, Nipasol, benzoic acid, sodium benzoate, sorbic acid, benzalkonium chloride. As a body-forming base, the composition can contain distilled water, polyethylene oxide 400, polyethylene oxide 4000, polyethylene glycol, propylene glycol, a phosphate buffer, a borate buffer, an acetate-borate buffer depending on a dosage form.

EFFECT: high therapeutic effectiveness, prolonged corneal contact of the preparation which reduces the number of instillations, avoids a risk of side effects and provides good tolerance.

5 cl, 5 ex

FIELD: medicine.

SUBSTANCE: invention refers to the veterinary science and is applicable for treating bovine digital dermatitis. A method involves applying a preparation in the form of an ointment of the following formulation, wt %: veterinary copper sulphate 35-45, zinc oxide 9-11, an ointment base - the rest. The preparation is made by mixing the ingredients until smooth. The preparation is applied on the involved regions 1-2 times with or without a protective dressing.

EFFECT: method is effective in treating bovine digital dermatitis.

1 tbl, 1 ex

FIELD: medicine.

SUBSTANCE: topical gel composition for treating erythema or a related symptom contains brimonidine 0.4 wt % to 0.6 wt %, preferentially in the form of brimonidine tartrate, a gelatinising agent, and at least one polyol. The topical application of the gel composition on the skin involved in erythema or having a manifestation of the related symptom has an effect on a serum or plasma profile of brimonidine with an average Cmax approximately 54±28 pcg/ml or less and an average AUC0-24h approximately 568±277 pcg·h/ml or less.

EFFECT: safe and effective treatment of erythema causing no inadequate drug-related side effects.

19 cl, 3 dwg, 5 tbl, 3 ex

FIELD: medicine.

SUBSTANCE: invention refers to a composition containing encapsulated triterpenic acid: betulinic acid, ursolic acid or derivatives thereof in the form of salts and esters, or triterpene alcohol - betulin, which may be used in medicine for treating and preventing viral infections caused by DNA and RNA-containing viruses, such as influenza viruses, oncogenic viruses, herpes virus, herpes zoster virus, as well as infections caused by gram-positive and gram-negative bacteria: Staphylococcus spp., Streptococcus spp., Enterococcus spp., Shigella spp., Escherichia spp., Salmonella spp., Proteus spp., Acinetobacter spp., Citrobacter spp., Pseudomonas spp., Serratia spp., Klebsiella spp., Antracoides spp., Cryptococcus spp., pathogenic fungi of the genus Microsporum, Trichophyton, Nocardia, Aspergillus, yeast-like fungi of the genus Candida, including multiresistant strains, as well as Actinomycetes and some pathogenic protozoa: Entamoeba histolytica, Trichomonas vaginalis. The invention presents the composition containing an active ingredient presented by 0.5 wt % of betulin or 0.5 wt % of encapsulated triterpenic acid: betulinic acid, ursolic acid or derivatives thereof in the form of salts and esters and others, and carriers presented by: β-cyclodextrins, fullerene, lecithins and polymers binding to the ingredients to form ingredient-carrier complexes, and excipients.

EFFECT: higher efficacy of using the composition.

3 cl

Wound-healing drug // 2517065

FIELD: chemistry.

SUBSTANCE: invention relates to a wound-healing drug which consists of stearic acid; castor oil; zinc stearate; 70% alcohol extract of a plant collection including oak tree bark, marigold flowers, wild chamomile flowers, nettle leaves, taken in ratio of 1:3:2:1, respectively; Na salts of fatty acids of wool fat; boric acid; vaseline; glycerine; triethanolamine; treated water; vegetable oil; Tipton weed extract; wild rose oil or sea buckthorn oil; 10% propolis oily solution; natural L-amino acid-peptide biocomplex obtained by extracting native paunch manure of ruminants with 2.0-3.0% NaCl solution; purified lanolin and derivatives thereof.

EFFECT: improved bactericidal, anti-inflammatory, regenerating, antioxidant and antimicrobial properties, drug does not have allergic action.

4 ex

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutical industry, namely to an agent for treating an oral mucosal involvement accompanying lichen acuminatus. An adhesive ointment for treating the oral mucosal involvements accompanying lichen acuminatus containing sea buckthorn oil and 0.5% prednisolone ointment, socoseryl dental adhesive paste and vitamin A in the specific proportions.

EFFECT: ointment is effective for treating the oral mucosal involvements accompanying lichen acuminatus.

3 ex

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to toothpaste compositions containing a fluoride ion source for reinforcement and protection of natural dental enamel. The composition contains the fluoride ion source and 0.01 to 1.5 wt/wt % of xanthane gum, 0.01 to 1.5 wt/wt % of Carbomer, 0.01 to 2.0 wt/wt % of carrageenan, the thickening agent silicone dioxide and the dental abrasive silicone dioxide; the composition has pH within 5.5 to 6.5.

EFFECT: using the toothpaste ensures good reinforcement and protection of the dental enamel by the above combination of the components in a combination with pH of the toothpaste composition, and provides good preservation of the composition applied on a toothbrush that is especially effective in preparing the toothpaste with colour strips.

10 cl, 5 tbl, 6 ex, 3 dwg

Up!