Method for prediction of rescue workers' adaptation level to personal protective equipment

FIELD: medicine.

SUBSTANCE: invention refers to medicine, labour safety, vocational selection of rescue workers. The invention can be used for vocational selection in the sectors of industry using personal protective equipment, as well as for the workers labour safety in the sectors of industry with harmful working conditions. The method involves vocational selection and duty control on the basis of electroencephalogram (EEG) values and cardiological findings. The examination is performed prior to and when using the personal protective equipment. The cardiological examination involves assessing the heart rate variability with using the amplitude-frequency spectrum Fourier analysis VLF at a vibration frequency within the range of 0.0033-0.04 Hz, LF - at a frequency of 0.05-0.15 Hz and HF - at a frequency of 0.16-0.80 Hz, and is five-staged: initial resting state, mental work load, recovery of mental work load, hyperventilation load, recovery of hyperventilation load. At the beginning, the heart rate variations and EEG are examined prior to using the personal protective equipment. If any of the five stages of the heart rate variation examination shows the pulse more than 90 beats per minute, as well as changes from the normal values of: approximating entropy - less than 180, LF - less than 6 point, an alpha wave amplitude - to 12 vibrations per second and the presence of the paroxysmal activity by EEG, the prevailing sympathetic nervous system is stated, or if any stage of the heart rate variation examination shows the pulse less than 60 beats per minute, as well as changes from the normal values of: blood pressure - more than 140/90 mmHg, VLF - more than 130 points, HF - more than 16 points, an alpha wave amplitude - less than 25 mcV, the prevailing parasympathetic nervous system is stated; a low level of adaptation to the personal protective equipment is predicted, and a rescue work is not recommended during the vocational selection; the examination is terminated. If the heart rate variation and EEG prior to using the personal protective equipment fall within the normal values, the heart rate variation when using the personal protective equipment is started with the patient examined when using the personal protective equipment and performing a cycle ergometer test, and recording the hyperadaptotic changes of the assessed values: VLF - more than 130 points in relation to the normal value when using the personal protective equipment and LF and HF vibrations; an incomplete or unfinished adaptation to the personal protective equipment, and the rescue worker is suspended from work for several hours; if VLF is more than 130 points recorded 10-15 min after activating the personal protective equipment, a good adaptation level to the personal protective equipment is predicted.

EFFECT: method enables assessing the vegetative nervous function and predicting the rescue workers' adaptation level to the personal protective equipment.

11 tbl, 5 ex

 

The invention relates to medicine, health, selection for the rescuers. Can be used for selection into industries, using personal protective equipment, as well as in the field of protection of workers of industrial enterprises with harmful working conditions.

Many years of experience in medical and psychophysiological studies of workers of metallurgical enterprises to assess the prognostic significance of those or other physiological parameters when exposed to adverse environmental factors and endogenous risk factors and conducting multidisciplinary testing of the functional state of the organism rescuers using different insulating PPE (ISIS) dictates the need to introduce new non-invasive well-established and reasonable modern physiological methods have predictive power. These methods can be used for selection, and dynamic observation. The main thing is that they are adequate list of medical contraindications admission to the work of paramilitary mine-rescue units ("Regulations on professional selection rescuers", M, 1999, Appendix 1) and have more information on the risk factors for pathological condition is, restricting the activities of the rescuers.

According to specifics of rescuers using self-contained breathing apparatus and great exercise, as well as increased emotional tension, this category of persons refers to a specific occupations requiring certain physiological and psychological reserves.

The urgency of the problem is that over the last 20 years there have been significant changes in the features of the coal enterprises and medico-physiological studies of human functional state, and professional selection of rescuers in the USSR is carried out in accordance with approved guidance, developed in Ukraine in the Donetsk Institute of labour and occupational diseases, in the future, after the collapse of the USSR this technique is almost no change was reinstated in Russia in 1999 and is used up to the present time.

In the regulations on the selection rescuers significantly expanded the volume of a variety of psychological tests in the evaluation of the psychophysiological state (takes 10 pages in Position 18 on the assessment). At the same time, there is no assessment of the cardiovascular system, the activity of the autonomic nervous system, which plays a decisive role in the adaptation of ISIS, and when desadaptation to death rescuers and miners. Offered only uninformative measurements HELL. Psychological tests often have no direct relation to the transferred load when using ISIS.

Human performance in extreme conditions may be limited not only by the presence of certain diseases, but above all, poor stability of physiological systems to the specific load ISIS, hypoxia and hypercapnia. At this point, are unmotivated actions, reduced physical performance. This section in the old "Position" represented.

In the professional selection of traditional methods of estimation of the functional state of the person (pulse, blood pressure, dynamometry, old psychological tests and other) do not fully reflect the peculiarities of work of the rescuers, the evaluation processes of fatigue, the initial manifestations of the disease, leading to disability, the formation of psychosomatic disorders, as well as technological processes in production.

For example, if there are clinical signs of a hangover substantive examination of the basic physiological indicators traditionally used (pulse, blood pressure, dynamometry) can be normal. These indicators can also remain within normal limits in an altered state of consciousness (for example, it is proved that the performance does not change when the ISM is United state of consciousness operators metallurgical works night shifts).

The lack of provisions: currently accumulated data on the occurrence of medical problems when using ISIS in miners and rescuers in the lengthening of the time of their use. No matching list of medical contraindications (Annex No. 1. Regulations on professional selection rescuers, M., 1999) and the use for these purposes approved diagnostic tests 1999, Especially for problems of loss of consciousness, autonomic crises, cardiovascular pathology. In the regulations on the selection rescuers significantly expanded the volume of a variety of nonspecific psychological tests in the evaluation of the psychophysiological state (takes 10 pages in Position 18 on the assessment).

Breathing in isolating regenerative oxygen breathing apparatus has an impact on the body rescuers following factors:

- long-term (over several hours) oxygen inhalation in high concentrations, reaching 80-90% by volume, which adversely affects physiological systems, acid-base status;

- additional resistance to the breath on the inhale and the exhale 100-300 PA (10-30 mm of water. Art.);

- adverse temperature and humidity conditions in the respiratory system of the respirator with 100%humidity of the inhaled air and the temperature is Roy his 39-42 degrees. Celsius or more, which disables the respiratory tract as a function of heat transfer and burdens thermoregulation;

- periodic inhalation of large quantities of carbon dioxide (1-1,5%vol.) if its incomplete absorption in the regenerative cartridge during very heavy work or at the end of the term of protection of the device.

the extra mass of the spacecraft (12-14 kg), which rescuers are forced to wear in the polluted atmosphere that during heavy physical work increases the energy consumption for 25-27%.

The work of the rescuers is a tedious, difficult or very difficult when performing unskilled manual of operations (consumption of more than 250 kcal/h or 293 j/s). High neuro-emotional stress due to work in an explosive atmosphere underground workings with risk to life, search and evacuation of victims from the underground workings. Required DC voltage of attention, hearing, vision, mobility in an untenable position when moving in horizontal, inclined and vertical openings.

Subject to the foregoing disadvantages requires careful evaluation of competency to persons, primarily for medical reasons and on the basis of the analysis of physiological risk factors, arriving at the mine rescue service in the position, such as respirators, and Jerzy is Naya check suitability of rescuers during the period of service.

These features make high demands on cardio-respiratory and autonomic systems of the body and the need to predict the activity of these systems in extreme conditions. That is, require an integrated complementary assessment of the functional state of the organism and the allocation of physiological risk factors of fitness to work.

However, in the approved regulations on the selection of rescuers in-depth evaluation of these systems represented.

Evaluation of the autonomic nervous system, simpato-vagal regulation, which plays a major role in the adaptation of the cardio-respiratory system to ISIS and the workload in Position no.

When the assessment of occupational health risks for miners conduct medical examinations of miners, further define the experience of their work when exposed to specific hazardous occupational factors or complex of harmful occupational factors, and the results of the examination, the number of patients suffering from occupational disease in selected professional group with specific work experience, i.e. also do not evaluate the activity of the autonomic nervous system, simpato-vagal regulation during adaptation of the cardio-respiratory system to ISIS.

Spend physiological examination registration electroe is cephalogram to identify gross and underlying organic brain lesions, contributing to the pathology of the Central nervous system. The survey consistently perform as the primary control device to work as periodic monitoring and maintenance of the learning process and emergency response training. When deciding on the competency on the results of inspection and testing allocate risk from operational staff. The method allows to increase the efficiency of selection and to ensure the possibility of its use in the definition of competency, but also do not evaluate the activity of the autonomic system and simpato-vagal regulation.

The objective of the invention consists in assessing the activity of the autonomic nervous system and forecasting the level of adaptation of rescuers to ISIS.

This object is achieved by a method for predicting the level of adaptation of rescuers to the individual remedies (ISIS), which includes professional selection and supervision during the period of military service on the basis of the electroencephalogram (EEG) and cardiac studies. The survey is carried out before the use of ISIS and when using it, and cardiac study is to assess the heart rate variability (HRV), which is performed using the frequency-amplitude spectral Fourier analysis: VLF frequency vibrations which deposits in the range 0,0033-0,04 Hz, LF - a with a frequency of 0.05 to 0.15 Hz) and HF with a frequency of 0.16-0,80 Hz, and is done in 5 stages: in the initial state of rest, mental stress, recovery after mental stress, hyperventilation load in the recovery period after hyperventilation load. At the beginning of the survey HRV and EEG to use ISIS and identifying any of the five stages of the research HRV heart rate over 90 beats/min, and the changes relative to normative values: the approximated entropy is less than 180, LF - less than 6 points, the amplitude of the alpha rhythm to 12 the number and appearance of paroxysmal activity on EEG, establish the predominance of the sympathetic nervous system. Or the detection at any stage of the study HRV heart rate less than 60 BPM, as well as the changes compared to the normative values of indicators: HELL - above 140/90 mm Hg, VLF - more than 130 points, HF - more than 16 points, the amplitude of the alpha rhythm - less than 25 µv, establish the predominance of the parasympathetic nervous system, predict a low level of adaptation to ISIS and in the professional selection do not recommend the work of the rescuers, the survey ceased. In that case, if the indices of HRV and EEG obtained before donning ISIS, meet regulatory pass to the study of HRV in ISIS, and the study was conducted while in ISIS and so the exercise test, and when you register the changes of the evaluated indicators by type of hyperodapedon: VLF - more than 130 points relative to the standard value when ISIS and fluctuations in loads LF and HF, predict incomplete or unfinished adaptation of ISIS and excluded rescuers from work for a few hours. And when the VLF - more than 130 points, recorded only after 10-15 min after inclusion in ISIS, predict a good level of adaptation to ISIS.

The novelty of the invention: first, we used modern methodological approaches in the analysis of the functional state of the organism rescuers when ISIS. New methodological approaches were the rst to describe positive hyperaptive changes in neuro-cardio-respiratory system when ISIS that allows you to easily overcome physical activity. First described negative predictive signs of HRV changes in the body that contribute to maladjustment or incomplete adaptation (energodefitsitnym processes, severe autonomic instability, and others) to ISIS. When determining the competency and for periodic inspections proposed to include additional methods of research that are not in the Position (1999).

The survey is carried out before the use of ISIS and when it is used.

- Cardiology the study conclusion is highlighted in the assessment of heart rate variability (HRV), which is performed using the frequency-amplitude spectral Fourier analysis: VLF frequency oscillations in the range 0,0033-0.04 Hz), LF - a with a frequency of 0.05 to 0.15 Hz) and HF with a frequency of 0.16-0,80 Hz, and is done in 5 stages: in the initial state of rest, mental stress, recovery after mental stress, hyperventilation load in the recovery period after hyperventilation load.

- At the beginning of the survey HRV and EEG to use ISIS and identifying any of the five stages of the research HRV heart rate over 90 beats/min, and the changes relative to normative values: the approximated entropy is less than 180, LF - less than 6 points, the amplitude of the alpha rhythm to 12 the number and appearance of paroxysmal activity on EEG, establish the predominance of the sympathetic nervous system.

Or when identification at any stage of the study HRV heart rate less than 60 BPM, as well as the changes compared to the normative values of indicators: HELL - above 140/90 mm Hg, VLF - more than 130 points, HF - more than 16 points, the amplitude of the alpha rhythm - less than 25 µv, establish the predominance of the parasympathetic nervous system, predict a low level of adaptation to ISIS and in the professional selection do not recommend the work of the rescuers, the survey ceased.

In that case, if the indices of HRV and EEG obtained before donning ISIS, meet regulatory pass to the study of HRV in ISIS, and the study was conducted while in ISIS and Bicycle stress test, and when you register the changes of the evaluated indicators by type of hyperodapedon: VLF - more than 130 points relative to the standard value when ISIS and fluctuations in loads LF and HF, predict incomplete or unfinished adaptation of ISIS and excluded rescuers from work for a few hours. And when the VLF - more than 130 points, recorded only after 10-15 min after inclusion in ISIS, predict a good level of adaptation to ISIS.

The essential features of the invention allows to obtain a new effect: allows you to more accurately and objectively assess the health status of the patient and to predict the possibility of working them into ISIS and as rescuers.

The analysis of HRV in combination with functional tests, including psychological, determines and predicts resistance to stress and exercise, and most importantly, when assessing neuro-cardio-respiratory system in terms of use of ISIS.

To do this, assess physiological indicators of the functional state of the organism rescuers of critical importance to the selection and identification of risk factors according to the list clinics is their status and diagnostics: EEG, including when using ISIS that can be identified organic diseases of the Central nervous system, psychiatric disorders, epilepsy and other seizures, autonomic dystonia, neurosis, alcohol and drug dependence, endocrine disorders, diseases of the spine.

Diagnostics functions of the autonomic nervous system on the basis of the analysis of heart rate variability - HRV (statistical, spectral and nonlinear analysis) with functional tests (5 stages), including the use of ISIS, identifies changes in the ANS in the form of pronounced vegetative dystonia, neurosis, organic diseases of the Central nervous system, addiction to alcohol and drug abuse, diseases of vegetative-vascular system, the spine and joints, disorders of the abdominal organs, endocrine disorders, disorders of musculoskeletal system, the degree of adaptation and disadaptation to ISIS, the degree of suitability of the operator's activity.

VEM, as a method of assessing physical health, and as a method of assessing the degree of adaptation to ISIS. Identifies the risks of diseases of the Central nervous system, cardiovascular system, autonomic disorders, nervousness, disorders musculoskeletal, endocrine disorders, and neuro-cardio-respiratory dysfunction to ISIS.

The method allows determining the competency of pornopasa the oil to evaluate the activity of the autonomic system and simpato-vagal regulation, as well as to determine the neuro-cardio-respiratory dysfunction to ISIS.

The study involved 15 men rescuers. The average age 31 years, work experience from 2 to 12 years. In dynamics studies performed 72 recording EEG, 72 ECG recording, 72 recording VEM-load and 252 session HRV with functional tests.

Research methodology the functional state when ISIS included several stages:

1. Stage and pre-clinical examination by a neurologist to assess body condition and identify the clinical manifestations of autonomic dysfunction; b) studies of the neural and hemodynamic Central nervous system - EEG, ECG; C) physiological analysis of autonomic software-based monitoring HRV with two functional tests (EDS studies 5 stages).

2. Stage - evaluation of the state or reaction to the use of respirators for 20 minutes without physical exertion includes repeated EEG and EDS study of the autonomic software.

3. Stage - VEM-load respirator (5 minutes, 60 Watt) assessing the response of the cardio-respiratory system to physical activity with simultaneous recording of the ECG.

4. Stage - assessment of body rescuers after removing the respirator (recovery period) re-analysis of the EEG, HRV. Self-report indicating the subjective sensations PR is the load or the reasons for the interruption.

Functional test with monitoring of HRV were of low intensity and included a countdown and an in-depth breath for 3-4 minutes. These samples have the opposite orientation (sympathetic and parasympathetic). Target loads - evaluation simpato-vagal balance and autonomic reserve. The inclusion of ISIS is also a kind of test for the evaluation of compensatory and adaptive processes.

Record HRV produced in sitting in a comfortable chair, used the topography of the electrodes, in which were recorded the high-amplitude R-wave ECG was Recorded at rest for such time, including 256 consecutive R-R-interval RR (initial state, background). Further, the recording continued with the presentation of mental workload by the mind (seven-test) - serial subtraction from 500 to 7. Then recorded the performance of RR intervals during rest after mental exertion. The following test hyperventilation. Conducted in-depth spontaneous breathing. And then restore after hyperventilation. All 5 stages of the research procedures were the same length - 256 RR intervals. If the average duration of cardiac intervals of 0.7 seconds each phase of the survey was about 3 minutes and the whole procedure entry DIF - about 15 minutes and consisted of the register is July 1280 consecutive RR intervals.

Sequence studies of ISIS included: check the initial state of the rescuers (EEG, ECG, HRV), neurological examination, and registration of these indicators for inclusion in ISIS, registration HRV after 5 minutes VEM load 60 watts. The repetition of physiological studies in the recovery period after turning off ICES.

To assess HRV used frequency-amplitude spectral Fourier analysis: VLF (very low frequency very low frequency range with the range of fluctuation within 0,0033 to 0.04 Hz), LF - low frequency (low frequency with a frequency of 0.05 to 0.15 Hz) and HF - high frequency (high frequency with a frequency of 0.16-0,80 Hz).

When excessive loads or when the pathology of the greatest difficulties in the circulation have subendocardialnah layers of the left ventricle, because the coronary blood flow is hindered by the high end diastolicheskoe pressure. In hypoxic conditions in the myocardium begin the process of anaerobic glycolysis with the overproduction of lactate, as well as violation of its utilization. Following this, the cells of the myocardium lose potassium ions, which leads to the violation of contractility. These processes are reflected either ECG or clinical condition of the examinee. To determine the pathology was conducted VEM sample. During surveys revealed that to determine any pathology adequate is about one VEM samples 60 W power with a duration of 5 minutes.

The first 15 minutes after putting on the respirator can be unpleasant subjective sensations (shortness of breath, sore throat) noted hyperaptive reaction autonomic software with the rise of HELL has changed autonomic profile, i.e. severe reaction was localized in the region of 10 seconds rhythms. Subsequently, these effects decreased and autonomic profile shifted to the field of parasympathetic activity, which was kept in the future in the field of respiratory rhythms. Normalized indices of HRV studies.

After removing the respirator HELL is normalized to the initial digits.

Thus, the dynamics of work in the respirator was characterized by competitive mechanisms of adaptation between 10 seconds baroreceptors and parasympathetic respiratory rhythms. And baroreceptors sympathetic component included in the period of adaptation to the respirator with a high amplitude (10 sec. rhythms). And the period of adaptation in the second hour was characterized by a steady parasympathetic orientation of vegetative processes that were in the original condition. The recovery period after removing the respirator was characterized, on the respiratory sample and after it, a pronounced strengthening medlennovolnovoj activity.

Although adaptive processes for inclusion in ISIS have common OS the features, each of the subjects was different individual characteristics.

The physiological phenomena of adaptation to ISIS (short and long) can result in bradycardia, initially reduced the depth of breathing, parasympathicotonia. At the level of the Central nervous system there is excessive activation of the mid-stem structures that increase beta activity in the EEG.

Adaptation to ISIS best seen in good physical health, transients from normative values of HRV to reaction hyperacutely as ischemia heart rate, strengthen and ischemia breathing, a significant increase in power colaminated, ten seconds and respiratory rhythms. A special case of adaptive processes could be the emergence of limit cycles HRV and moved frequency bands of the breath in the lower region. Significantly less likely to move into a higher region of the frequency range HF.

Within each phase DIF-research activities, inclusion in ISIS, after VEM-load, recovery period, after removal of ISIS) technique allowed us to test the work of providing basic system. For these purposes, each time it was repeated in the dynamics of mental (reverse scored) and respiratory (arbitrary-depth breath) functional tests. This technique allowed us to see what systems in the body VK is uchitsya under load and recovery processes. In particular, the inclusion of neuroendocrine cerebral structures high level, i.e. stronger colaminated rhythms 0.005 to 0.01 Hz (from 30 sec to 1.5 min) or peripheral 10 seconds and respiratory rhythms. These studies highlight the prognostic vegetative and energy processes or criteria that limit the performance or Vice versa, allowing for a good physical exertion.

Functional tests to some extent simulate the problems faced by rescuers in a real situation and allow you to predict your body's response to these situations.

Adaptive processes to ISIS are complex interconnection. The activity of the Central nervous system has independent significance (decision making, emotions, orientation in space and time and so on). At the same time the Central nervous system plays an important role in maintaining the stability of the internal organs, cardio-respiratory system, locomotor activity, etc.

The body includes double-compensatory-adaptive processes: (a) equip the insulating means; b) the rest period in the insulating means and, especially, when their removal. Most used melanophloia processes (neuroendocrine, metabolic) to restore vital body systems.

The inclusion body of gornospasatel is th at ISIS requires quick realignment life support systems neuro-cardio-respiratory functions. In this regard, adaptive processes depend on the initial state of the organism, its degree of preparedness, and on the other hand the technical condition of equipment means (air flow, gas composition, resistance to breathing, the weight of the device and so on).

The autonomic nervous system provides the most important functions of adaptation of the organism to various environmental factors and preservation of homeostasis. Contraindication to work with ISIS are extreme types of autonomic software. Here are two opposite types of abnormalities in autonomic state: (a) with the expressed sympathicotonia and b) with a predominance of the parasympathetic nervous system. Formal negative clinical signs, limiting efficiency were the first shows the original stable tachycardia (heart rate 100 beats/min at rest); the second is on the background of bradycardia (heart rate of 50 beats/min) - high blood pressure. These types of demonstrative and instructive in the sense that all adaptive processes in healthy rescuers occur in the Central zone of the autonomic homeostatic software. Between these two extreme types of deviations that are contraindications (see Regulations on professional selection rescuers, M., 1999, shows the diversity of adaptive processes. Violation of adaptive ol the processes is an important indicator of professional selection and training mode rescuers.

Example 1

The rescuer of B-in EV (36 years) with arterial hypertension and changes in autonomic software type hyperdipsia and strengthening colaminated rhythms to 800 MS2/Hz. These changes have taken place against the background EEG in the form of flattening the main rhythm 10 Nr./s, which is typical for enhanced mid-stem activation. Table 1.

Table 1
Hyperodapedon the rescuer with arterial hypertension
These changes are logged to the application of ISIS
backgroundmind. load.vos. after the mind. loadalpha rhythmapprox. entropy
VLF809568267Less than 15 µv220%
LF220280199
HF13398100
PS525352
HELL150/110155/110150/100

Considering high blood pressure, low pulse, the flattening of the alpha rhythm in the EEG and changes in autonomic software type hyperdipsia can talk about the contraindication as rescuers.

Example 2

In the opposite type of disturbance adaptive processes consider the results of the study of breathers B-she EJ (26 years). Expressed sympathicotonia, tachycardia (heart rate 100 beats/min), a marked reduction of the approximated entropy (125 while the norm is 200). This excitation of the autonomic nervous system is combined with Central nervous system excitation, the frequency of the basic rhythm to 12 Nr./s and the appearance of paroxysmal activity coming from mediobasal departments temples. Table 2.

Table 2
Sympathicotonia and energy from the rescuer with tachycardia
These changes are logged to the application of ISIS
backgroundmind. support vos. after the mind. loadalpha rhythmapprox. entropy
VLF32,5325 µv, 12 Nr./s, slow waves in the temples125%
LF0,30,40,3
HF000
PS9810098
HELL120/80120/80120/80

The increase in heart rate over 90 beats per minute at normal pressure, increased alpha rhythm over 12 Nr./s and changes in autonomic software by type of energy is also a contraindication to work as rescuers.

Examples of maladaptation to ISIS.

There is partial or incomplete adaptation to ISIS. In addition to the conditions that are contraindications to physical activity, there are a number of transients, which is not I who are contraindications, however, cause a variety of complaints and reduced physical performance.

One of such forms is pronounced instability of the autonomic software. Instability can be triggered by changes in the initial condition (fatigue, stress, emotional stress and other reasons), high load or deteriorating conditions of ISIS. Here are two examples of the appearance of the instability of the autonomic provide the rescuers with different experience.

Example 3

Rescuers B s 23 years old, athletic, work experience of 1 year. 15.01.07 - pulse 82 beats./min and BP - 100/70, registered low indices of parasympathetic activity. Stable domination 10-second rhythm. When donning the respirator during and after VEM-load there are a variety of complaints about the discomfort in the head, throbbing in his head, metallic taste in the mouth, feeling of shortage of air. Table 3.

Table 3
15.01.07. Before donning ISIS
backgroundmind. load.vos. after the mind. loadalpha rhythmapprox. Entropia
VLF12613012640 μv, 10 Nr./s225%
LF221920
HF15812
PS808280
HELL100/70100/70100/70

Before donning ISIS all indicators are normal and contra-indications to work there.

23.01.07 registered hyperaptive background, which was repeated on the respiratory load and after it, with high parasympathetic activity, which previously was not. The inclusion of ISIS strengthened hyperaptive changes, and hyperventilation pulse with 61 slowed to 55 and okolomindalny rhythms from 470 to 870. After VEM-load related complaints of reaction of intermittency: the sudden change of sympathetic to parasympathetic activity and Vice versa. This change is only visible if the sequential analysis of the Tahoe the scheme and its phase portraits and cannot be detected purely statistical analysis. Table 4.

Table 4
23.01.07. Before donning ISIS
backgroundmind. load./g/atvos. after the mind. load/g/alpha rhythmapprox. entropy
VLF221132/439439/47140 μv, 10 Nr./s225%
LF6619/4343/87
HF10967/4444/155
PS5659/6160/59
HELL130/90125/85125/80

23.01.07 the blood pressure and pulse are normal, and only DIF visible changes in autonomic software type hyperdipsia, which increases the load, which is a contraindication for this day.

Table 523.01.07. In ISISbackgroundmind. load./g/atvos. after the mind. load/g/alpha rhythmapprox. entropyVLF87206/950449/81140 μv, 10 Nr./s223 unitsLF5046/235179/124HF5745/23582/68PS6161/6255/59HELL130/90130/90/120/80130/90/120/80

After putting on ISIS changes in autonomic software type hyperdipsia has increased dramatically. Cardiorespiratory system works in emergency mode, which is bad for health and is a contraindication to work that day.

<> Example 4

The second example shows a pronounced instability during adaptation to ISIS of the test X-ova E.N., 36 years. Despite the unusual physiology status with a variety of vegetative-dystonic signs it is well adapted to the rescuers and always coped well with a load. Work experience of 15 years. However 05.04.07, there were problems that have emerged in the pronounced instability of the functional state and cardiodynamics processes. This instability appeared when ISIS and gradually disappeared during the recovery period: the initial state is unstable in the transition from 60 beats./min to 75 beats./min When ISIS - autonomic instability has increased dramatically, especially on the mental and respiratory load. Pulse 75-80 beats./min, and in another case - 65 beats./min. It is accompanied by shortness of breath. The recovery is still unstable, but is much closer to its original state. Instability appeared when ISIS and associated loads for hyperaptive initial state, which could be triggered by the previous exhaustion the day before the laboratory tests (after the change).

Table 6
05.04.07. Before donning ISIS
backgroundmind. load./g/atvos. after the mind. load/g/alpha rhythmapprox. entropy
VLF404179/182138/18960 μv, 10 Nr./s222 unit
LF7017/2121/40
HF41/12/2
PS6375/7368/68
HELL110/85115/80/120/90120/85/110/90

Before donning ISIS pulse and blood pressure in normal and only DIF record changes to the autonomic software type hyperdipsia is the result of fatigue, which is a contraindication for this day.

Table 7
05.04.07. In ISIS
backgroundmind. load./g/atvos. after the mind. load/g/alpha rhythmapprox. entropy
VLF5331344/929495/39960 μv, 10 Nr./s219 units
LF2933/5522/29
HF37/53/3
PS6575/7466/71
HELL120/80120/80/130/90125/80/130/90

After putting on ISIS after 1 hour pulse and HELL are normal and only HRV increase dramatically changes autonomic software type hyperdipsia and there are complaints about the lack of air is the result of fatigue, which is a contraindication for this day.

Table 8
05.04.07. After the IP is C
backgroundmind. load./g/atvos. after the mind. load/g/alpha rhythmapprox. entropy
VLF729145/20598/26160 μv, 10 Nr./s212 unit
LF3929/2921/18
HF51/22/2
PS6672/7368/71
HELL110/80120/90/120/90120/90/110/90

After removal of ISIS pulse and blood pressure in normal and only DIF is saved, although somewhat less pronounced changes in autonomic software type hyperdipsia.

Example 5

Consider the example of a typical adaptation of ISIS of the test H-AA, 27 years. The first 10-15 minutes after putting on ISIS and unpleasant subjective sensations (breathing difficulties, sore throat) marked what is the VLF increase above 130 points. Further VLF gradually returns to the original level and is retained even after VEM load, which is a good prognostic sign and characterizes a good level of adaptation to ISIS. Table. 9.

Table 9
Initial state
backgroundmind. load./g/atvos. after the mind. load/g/alpha rhythmapprox. entropy
VLF49116/78136/12940 μv, 10 Nr./s230%
LF4193/7237/68
HF48/343/6
PS7779/8176/80
HELL130/80120/80/120/70125/80/130/70

Pokazatel the VLF, The blood pressure and pulse are normal, which suggests that a person can work with rescuers.

Table 10
10 minutes after putting on ISIS
backgroundmind. load./g/atvos. after the mind. load/g/alpha rhythmapprox. entropy
VLF134115/162285/48740 μv, 10 Nr./s224 unit
LF2375/6260/104
HF6027/5944/40
PS7372/7072/71
HELL130/90125/85/120/85125/80/125/85

Equip ISIS after 10 minutes VLF has increased 3 times, and HELL, and the pulse is not changed.

Table 11
After VEM load
backgroundmind. load./g/atvos. after the mind. load/g/alpha rhythmapprox. entropy
VLF5082/80132/4840 μv, 10 Nr./s232 units
LF4927/3842/28
HF5239/1713/16
PS7773/7773/75
HELL120/80120/90/120/90120/90/120/90

After VEM-load (60 watts for 5 minutes) indicators VLF remained normal, that is a sign of good adaptation of ISIS.

Adaptation to ISIS or maladjustment depended on the following reasons: from the original standing of the subject, their adaptive reserves (t is enrevanche, physiological risk factors, processes, fatigue, emotional stability, short-term and long-term processes of adaptation); the duration and level of physical activity; from the state of the engineering and technical support of ISIS due to their level of reliability, the ratio of O2/CO2resistance to breathing.

The processes of exclusion are best manifested in the study of autonomic supply of the organism at low loads (stress instability, ventilation) and mainly when turning on the respirator and small physical activity.

The most appropriate and sensitive methods of estimation of the functional state of the person when ISIS are methods of analysis of autonomic software using HRV. Other indicators - HR, BP, EEG are important tools, but may not change when ISIS and fatigue. Methods of analysis of HRV have predictive power.

Hyperaptive changes in HRV in conjunction with the restructuring and strengthening of the functions of the neuro-cardio-respiratory systems begin immediately after the inclusion of subjects in ISIS and provide the best conditions for overcoming physical activity. The adaptation period is 10-15 minutes.

Adaptive processes are manifested as changes in the structures of the cardio-respiratory support, the increase in total power or range of the spectrum of HRV, especially baroreceptors and respiratory function. At the level of the Central nervous system EEG reflect the strengthening of the functions of the mid-stem structures (reaction activation paroxysmal activity, pronounced hemispheric asymmetry).

The processes of exclusion and incomplete adaptation manifested in low energy medlennovolnova processes HRV in the original background, the absence of adaptive responses to inclusion in ISIS, tachycardia greater than 100 beats/min and the original HELL over 140/90, pronounced instability of HRV.

The recovery period after VEM-load of ISIS the longer than vyrazennie load and occurs when the gain is very slow oscillations of HRV and baroreception.

VEM-load low-intensity proved to be the best indicator of the health of the rescuers in ISIS complementary prognostic vegetative criteria of the functional state of the organism.

The analysis of HRV in combination with functional tests, including psychological, determines and predicts resistance to stress and exercise, and most importantly, when assessing neuro-cardio-respiratory system in terms of use of ISIS.

A method for predicting the level of adaptation of rescuers to the individual remedies (ISIS), on the emitting professional selection and supervision during the period of military service on the basis of the electroencephalogram (EEG) and cardiac studies characterized in that the survey is carried out before the use of ISIS and when using it, and cardiac study is to assess the heart rate variability (HRV), which is performed using the frequency-amplitude spectral Fourier analysis: VLF frequency oscillations in the range 0,0033-0.04 Hz), LF - a with a frequency of 0.05 to 0.15 Hz) and HF with a frequency of 0.16-0,80 Hz, and is done in 5 stages: in the initial state of rest, mental stress, recovery after mental stress, hyperventilation load in the recovery period after hyperventilation load; at the beginning of the survey HRV and EEG to use ISIS and identifying any of the five stages of the research HRV heart rate over 90 beats/min, and the changes relative to normative values: the approximated entropy is less than 180, LF - less than 6 points, the amplitude of the alpha rhythm to 12 the number and appearance of paroxysmal activity on EEG, establish the predominance of the sympathetic nervous system, or the detection at any stage of the study HRV heart rate less than 60 BPM, as well as the changes compared to the normative values of indicators: HELL - above 140/90 mm Hg, VLF - more than 130 points, HF - more than 16 points, the amplitude of the alpha rhythm - less than 25 µv, establish the predominance of the parasympathetic nervous system, predict neither the cue level of adaptation to ISIS and in the professional selection do not recommend the work of the rescuers, the survey stop, if the indices of HRV and EEG obtained before donning ISIS, meet regulatory pass to the study of HRV in ISIS, and the study was conducted while in ISIS and Bicycle stress test, and when you register the changes of the evaluated indicators by type of hyperodapedon: VLF - more than 130 points relative to the standard value when ISIS and fluctuations in loads LF and HF, predict incomplete or unfinished adaptation of ISIS and excluded rescuers from work for a few hours; and when the VLF - more than 130 points, recorded only after 10-15 min after inclusion in ISIS, predict a good level of adaptation to ISIS.



 

Same patents:

FIELD: medicine.

SUBSTANCE: patient is trained by challenging to imagine a paretic limb movement and controlling the imagined movement. An electroencephalography is recorded; the recorded data are transferred to a computer for synchronous processing, and arousal reaction signals of a sensorimotor rate responsible for the imagined movement are isolated by means of an EEG pattern classifier according to the Bayes method. Identification results of the mental challenge are presented to the patient by a visual feedback in the form of a mark on a monitor. The mark re-position testifies to accuracy of the challenge. The imagined movement challenge is presented for 10 seconds. The training course makes 6-12 days, one training a day, of the length of 20-30 minutes every 1 to 4 days.

EFFECT: method provides more effective rehabilitation that is ensured by the feedback training in the conditions enabling the patient controlling the imagined paretic limb movement visually.

3 dwg, 4 tbl, 2 ex

FIELD: physics.

SUBSTANCE: method includes rendering an image which creates a depth and volume effect (IDE); detecting electrical activity (EEG) of the brain for white sheet (IWS) rendering and for image IDE rendering; calculating the sum of the overall coherence amplitude on all derivations and components of EEG rhythms, first for IWS rendering (Σ(CHАIWS)), and then for image IDE rendering (Σ(CHАIDE)). If the value Σ(CHАIDE) is greater than Σ(CHАIWS) by 1.8 times or more, the capability for three-dimensional sensing of flat images is determined.

EFFECT: method enables to obtain an objective evaluation of the capability for three-dimensional sensing of flat images, which is achieved owing to use of coherent EEG analysis.

2 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine, and may be used in occupational pathology. Person's open eyes are exposed to a white light of a colour temperature varying within the range of 1700 K - 10000 K. An electroencephalogram is recorded; its spectral analysis is performed to state the effect to be activating as shown by a power spectrum of alpha and theta waves reducing by more than 25% of background values.

EFFECT: method enables an individual selection of a colour temperature having the activating effect.

2 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine and may be used for assessing the light exposure generated by a light-emitting-diode source on the functional status of human brain cortex. The white light exposure covers individual's open eyes at colour temperature 1700-10000 °K, illumination 80-300 lx at the eye level. That is followed by electroencephalogram recording and spectral analysis. If observing an increase or a decrease of alpha or teta wave spectral power by more than 25% of a baseline value, the light exposure is considered to be physiologically active, and by less than 25% - as physiologically neutral.

EFFECT: method provides more reliable assessment of the functional status of human brain that is ensured by biological activity rating within the alpha and teta wave range.

4 tbl, 4 ex

FIELD: chemistry.

SUBSTANCE: invention refers to medicine, and may be used for changing the functional status of an individual. The individual's open eyes are exposed to white light at colour temperature 1700 °K or 10000 °K, at lighting intensity 200 lx at the eye level. That is followed by electroencephalogram recording and spectral analysis. If an alpha wave spectral power increases by more than 50%, while a teta wave spectral power increases by more than 25% of a baseline value, the effect is considered to be relaxant.

EFFECT: method enables assessing the action of colour temperature individually that can cause the relaxant effect on an individual.

2 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely dentistry. An encephalogram (EEG) is recorded in patients with the disturbed cerebral hemodynamics. The EEG is repeated with an occlusal load using 10-20 g of comb honey for 3-4 minutes. If a post-therapeutic alpha rhythm recovers or prevails on the EEG, the conducted orthopaedic alignment is considered to be effective.

EFFECT: method provides more reliable estimation of the orthopaedic alignment of dental patients suffering a cerebrovascular pathology that is ensured by using the occlusal load.

4 dwg, 1 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine and may be used to estimate the indications for prescribing drug preparations incompatible with alcohol ingestion, in addictology, psychiatry, as well as psychotherapy. There are performed electroencephalography and psychological testing: the first stage involves electroencephalography (EEG) in the patients diagnosed with alcohol dependence syndrome for the presence of short wave, desynchronosis and asymmetric bioelectric brain activity, disturbed alpha activity; the given study aims at finding the presence or absence of an organic pathology of brain functioning related to disturbed bioelectric activity. At the second stage, the patients with EEG findings showing no signs of an organic brain involvement are estimated considering the personal nonverbal emotional attitude system using colour repertory grid (CRG) techniques with using groups of alcohol-related objects and displaying Luscher colour cards. Pearson linear correlation coefficients of the elements and constructs to be further processed using a principal component analysis procedure. The detected factor loadings of the two most important components are used as two-dimensional element coordinates when constructing a graphical model of the attitude system of the person being tested. The presence of high conformity in the two representational personal emotional attitude system (verbal and nonverbal) gives evidence of the intact and adequate personality motivation sphere and serves as an indication for prescribing drug preparations of opioid receptor antagonists (naltrexone) and a cognitive behaviour therapy of alcohol dependency. The presence of low conformity is a sign of such disturbances of the motivation sphere that neutralise possibilities of psychotherapeutic methods and serves as a proof for prescribing drug preparations incompatible with alcohol ingestion (disulphiram, cyanamide).

EFFECT: method enables the objective and accurate estimation of the correctness of indications in predicting the effective use of drug preparations incompatible with alcohol ingestion, within the alcohol dependence therapy.

1 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to anaesthesiology, and may be used in assessing an adequate general anaesthesia in the children aged from 4 to 14 years old. That is ensured by pre-anaesthetic and intra-anaesthetic intraoperative recording of long-latency auditory evoked potentials. That is followed by summing up initial latencies of first three pre-anaesthetic peaks (P1, N1, P2) to calculate sum A, subtracting the sum of the latencies of the first three intraoperative peaks (P1, N1, P2) to calculate sum B. The A to B relation is multiplied by 100. A percentage of the latencies of the intra-anaesthetic peaks P1, N1, P2 to the pre-anaesthetic values is considered as the adequate general anaesthesia. For the children of the first age group of 4-6 years old, the general anaesthesia is considered to be adequate, if the percentage is 140-253%; for the children of the second age group of 7-9 years old, the adequate general anaesthesia is shown by the percentage of 133-253%; for the children of the third age group of 10-12 years old, the adequate anaesthesia is shown by the percentage of 159-190%; and the percentage of 125-271% provides the adequate general anaesthesia for the children of the fourth age group of 13-14 years old.

EFFECT: method provides the adequate and easy assessment of the anaesthesia ensured by reducing a time of examination and simplicity of data interpretation in the form of one three-peak wave.

1 ex, 6 tbl

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to neurophysiological methods of examination. Registration of EEG is carried out, total power of modal fluctuation in alpha-rhythm range in one of leads is determined and FRα1 index is calculated as ration of said power to total power of all alpha range fluctuations in the same lead. Value of the sum of power of fluctuations, located ±0.5 Hz on the right and on the left from maximal power value, including maximal value, is determined, and FRα2 index is calculated as ratio of the obtained sum of power to total power of all fluctuations of alpha-range in the same lead. Intensity of brain affection is determined by comparison of obtained FRα1 and FRα2 values with standard values.

EFFECT: method makes it possible to determined quantitative ratio of alpha-rhythm, characteristic of separate nosologic units in psychiatry.

2 tbl, 1 dwg

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to pediatrics and can be used in neurology, medical psychology and psychiatry. Clinical examination of children is carried out by complaints, anamnestic information and data of physical examination. Assessed are: symptoms of vegetative manifestations at the moment of examination and peculiarities of sensomotor reactions: weight and length of body at birth, gestation age, response to stimulation in children of first year of life, sleep in children of first year of life, EEG in children of early age, parasomnia, enuresis, meteosensitivity, headaches, vessel lability, vestibulopathy, peculiarities of motor sphere, feeding behaviour, skin manifestations, course of infectious and somatic diseases, menstrual disorders in adolescent girls, brain ultrasound examination. Connection of said disorders with predominant dysfunction of right or left brain hemispheres is determined.

EFFECT: method makes it possible to increase reliability of diagnostics, which is achieved due to taking into account vegetative reactions and disorders in child of first year of life.

1 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: cardiorhythmography is recorded during an active orthostatic test, and a heart rate variability (HRV) is analysed. During the active orthostatic test, the patient is placed in an initial horizontal position, then transferred into the vertical position, and then into the horizontal position again. If the amplitude of HF waves initially increases more than LF waves in the horizontal position by more than 30%, a prevailing parasympathetic effect is diagnosed. If the amplitude of HF and LF waves decreases after the patient is transferred into the vertical position by more than 30% of the values in the initial horizontal position, vegetative insufficiency is diagnosed. If the amplitude of HF waves decreases after the patient is transferred into the vertical position by more than 80% of the initial value in the horizontal position, a fast adjustment of the parasympathetic department to the changes is diagnosed. If the amplitude of VLF waves increases after the patient is transferred into the vertical position by more than 30% of the initial value in the horizontal position, activation of the supra-segmentary vegetative nervous system is diagnosed.

EFFECT: method provides more reliable diagnosing that is ensured by determining the mechanism of orthostatic test adaptation.

2 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: intraoesophageal pH monitoring and Holter monitoring are recorded daily. The heart rate variability is estimated in the aggregate with an analysis of a nocturnal heart rate trend. If finding more than 5 episodes of high heart rate dispersion coinciding with reflux episodes, or if a nocturnal structure comprises more than 50% of the episodes, the disturbed vegetative regulation of heart rhythm related to gastrooesophageal reflux disease is diagnosed.

EFFECT: technique enables diagnosing the extra-oesophageal manifestations of gastrooesophageal reflux disease at the early stage of the disease after the subjective manifestations have been observed.

FIELD: medicine.

SUBSTANCE: invention relates to medical equipment. An ECG monitoring system for detecting infarct-related coronary artery associated with acute myocardial infarction comprises the number of electrodes for data collection by electrical cardiac activity from various observing points spaced from the heart. An ECG data collection unit is related to the electrodes. An ECG processor responses to electrode signals to form a set of lead signals and detects ST rises in the lead signals. The display responses to the detected ST rises and graphically displays each set of the given ST rise in relation to the anatomical positions of the leads. The graphical display identifies the suspected infarct-related coronary artery or branch associated with acute ischemic stroke. The ECG signals is n-leads are received. The ECG signals are analysed for the consistency with the ST rise data. The each set of ST rises is graphically displayed in relation to the anatomical body positions. The stages of receiving and analysing are repeated some time later. The each set of ST rises derived some time later are graphically displayed and compared to the previous displayed ST rises. A comparative graphic display is used to display the time variation of a coronary disease symptom associated with the specifically identified coronary artery or branch.

EFFECT: using the invention enables reducing the length of diagnosing.

15 cl, 18 dwg

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to cardiology. ECG examination is performed to patient. Registration of signal-averaged ECG and transesophageal electrocardiostimulation (TE ECS) are carried out. Duration of filtered wave "P" (FiP-P) of signal-averaged ECG, dispersion of wave "P" (Pd), frequency threshold of arrhythmia induction (FTAI) and its duration are determined by means of TE ECS, risk of atrium fibrillation development (RAFD) being determined by original mathematical formula. If RAFD values are to 0.5, high during 1-3 months risk of AF development is identified. If values are from 0.5 to 1.5 - average from 3 months to 1 year risk of AF development. If values are higher than 1.5 - low, more than 1 year risk of AF development is identified after the first examination of patient.

EFFECT: method increases accuracy of determining risk of AF development after the first examination due to analysis of interaction of ECG and TEECS indices.

5 tbl, 4 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, specifically surgery and functional diagnostics. The supine heart rate is recorded and represents a baseline test, while the standing heart rate measured is an orthostatic test for 30 sec. The regulatory system activity index (RSAI) is described in points 1 to 10. An increase of this value relates to the deteriorating body adaptive possibilities; the RSAI value of 3-10 points enables predicting the postoperative wound complications.

EFFECT: method enables predicting the postoperative complications following the replacing hernia repair for postoperative hernias.

4 dwg, 3 tbl

FIELD: medicine.

SUBSTANCE: invention relates to medicine, particularly endocrinology and diabetology. There are involved examining heart rate variability (HRV) followed by spectroscopic analysis and functional testing. Those are added with determining non-linear values: deterrent fluctuation analysis (DFA) and approximated entropy (ApEn). If observing the initial amplitude decay of the HRV spectral components - VLF less than 30 points, LF less than 15 points, HF less than 15 points, DFA more than 0.7, ApEn less than 180, lack of functional response - autonomic cardiac sympathovagal neuropathy is diagnosed. If observing the normal amplitude of the HRV spectral component -VLF more than 30 points, low LF values less than 15 points, HF less than 15 points, DFA more than 0.7, ApEn less than 180, lack of functional response LF, HF - autonomic cardiac vagal neuropathy is diagnosed. If observing the initially normal amplitudes of the HRV spectral component -VLF more than 30 points, LF more than 15 points, HF more than 15 points, DFA more than 0.7, ApEn more than 180, lack of functional response LF, HF - autonomic cardiac subclinical neuropathy is diagnosed.

EFFECT: method enables early diagnosing and typing of autonomic cardiac neuropathy for the purpose of specifying a therapeutic approach.

3 tbl, 3 ex

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to neurology, therapy, family medicine, and can be used for selection of tactics for treatment of tension headache. For this purpose level of peripheral heart vegetative balance is determined in patient by analysis of index of sympathetic-parasympathetic relationship (LF/HF) in spectral analysis of cardiac rhythm. If LF/HF index increases higher than 2.0 conv. units, psychotropic drugs are introduced into therapy for relief of anxiety and/or depression.

EFFECT: method ensures possibility to stratify patients, requiring introduction of psychotropic drugs, thus making it possible to optimise treatment and increase its efficiency due to account of individual peculiarities of heart vegetative balance.

3 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to neurology and hepatology. Multi-level neurodynamic analysis of cardiorhythmograms is registered and realised by means of rhythmocardiograph and hardware and software complex "Omega-C". Determined are indices, reflecting: "A" - association of all, but mainly peripheral rhythmic processes, "B1" - degree of equilibration of sympathetic and parasympathetic effects on sinus node of heart, "C1" - state of central subcortical regulation, "D1" - state of central cortical regulation. Diagnostics index (YHE-L) is calculated in patients with chronic liver diseases by formula: YHE-L= -1.5 + 0.003*A + 0.013*B1 + 0.006*C1 + 0.053*D1. If YHE-L value is from -0.47 to 0.49, hepatic encephalopathy of latent stage in patients with chronic liver diseases is determined.

EFFECT: method makes it possible to increase reliability of diagnostics of hepatic encephalopathy of latent stage.

8 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: invention refers to occupational medicine. Individual state and performance values are estimated by four-score scale. Zero points if no symptoms observed, 1 point - the symptom is slightly manifested, 2 - moderately, 3 - significantly. A fatigue index (FI) is calculated as an arithmetic mean value. Electrocardiography is recorded to estimate cardiac rhythm variability, to calculate Am, Si, LF, heart rate. A modification coefficient (M) is calculated for each value by formula: wherein Ai is a value of one of the following signs, Amax and Amin are change ranges; : Am min 3.5, Am max - 98; Si min - 2, Si max - 950; LF min - 5, LF max - 90; heart rate min - 40, heart rate max -120; a vegetative regulation index (VRI) is calculated by formula: If the FI value is 0.6 points or less, and the VRI value is 10 or less, the state is considered to be optimal; the FI value 0.6 points or less and the VRI value more than 10 show the borderline state; the FI value more than 0.6 points and the VRI value is 10 or less means the satisfactory state; while the FI value exceeding 0.6 points and the VRI value exceeding 10 providing stating defatigation.

EFFECT: method extends the range of products for detecting defatigation in operators.

7 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely cardiology, normal physiotherapy, pathological physiotherapy. A daily curve of blood pressure is recorded. It is followed by spectral analysis by the method of continuous wavelet transformation. A frequency power of the blood pressure curve a is determined in the moment b by mathematical formula. Scalograms are drawn on the basis of the wavelet coefficient on the segment [bj, bj] by mathematical formula. Physiologically relevant frequency ranges are selected at the scalograms on the basis of distances between adjacent local minimums on the scalogram curve by formula.

EFFECT: method provides weak influence of vegetative nervous system and humoral effects on the blood pressure curve at the various stages of ontogenesis, in health and disease, both in rest, and in transition processes.

1 ex, 2 dwg

FIELD: medicine.

SUBSTANCE: invention can be used to identify a high risk of developing impaired glucose tolerance in patients with stable effort angina with underlying administering beta-adrenergic blocking agents with no additional vasodilating properties. Therapy is preceded by conducting 2 exercise tests on the same day to achieve a threshold load power according to the same protocol, initially and 2 hours after administering a single dose of the beta-adrenergic blocking agents. If observing an interval gain of 120 seconds and more from the beginning of the load to the angina attack and/or reduction of an ischemic ST segment on the electrocardiogram not less than 1 mm at the 2nd load as compared to the 1st load, a risk of impaired glucose tolerance is considered to be high. A glucose tolerance test is carried out in these patients 4-5 weeks after the scheduled administration of the beta-adrenergic blocking agents. If impaired glucose tolerance is detected, administering the beta-adrenergic blocking agents is withdrawn. If the 2nd load as compared to the 1st load shows an interval to the angina attack and/or reduction of the ischemic ST segment on the electrocardiogram at a depth not less than 1 mm increasing less than by 120 seconds, a risk of developing impaired glucose tolerance is considered to be negligible. Treatment of these patients with the beta-adrenergic blocking agents is continued without the glucose tolerance test required.

EFFECT: method provides preventing carbohydrate metabolic disorders by the early identification of the high risk of developing impaired glucose tolerance in the given patients by detecting a compensatory increase of the glucose consumption with insulin resistance and a lower availability of free fatty acids to provide myocardial energy needs.

6 ex

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