Method for activating effect of optical emission generated by light-emitting-diode source on human functional status

FIELD: medicine.

SUBSTANCE: invention refers to medicine, and may be used in occupational pathology. Person's open eyes are exposed to a white light of a colour temperature varying within the range of 1700 K - 10000 K. An electroencephalogram is recorded; its spectral analysis is performed to state the effect to be activating as shown by a power spectrum of alpha and theta waves reducing by more than 25% of background values.

EFFECT: method enables an individual selection of a colour temperature having the activating effect.

2 tbl, 2 ex

 

The invention relates to medicine and can be used to provide an activating influence on the functional state of the person by light radiation from the led source.

Currently, there is a wide spread of new light sources based on light-emitting diodes. Such semiconductor light sources have not only incredibly powerful, but if they are built on the principle of RGB mixing) and the ability to vary the quality (color, range), quantitative (intensity) and modulation (frequency of outbreaks) light parameters for a given algorithm. This quality is called "intellectual light".

The closest in technical essence and the achieved result is a way to determine the impact on the functional state of a human light radiation (RU, patent No. 2217182. CL A61N 5/06, 2001.)

The disadvantages of this method is the impossibility of providing an activating influence on the functional state of the person by light radiation.

The technical result, which directed the present invention is the possibility of providing an activating effect on the functional state of the human light emission from an led source.

The specified technical the ski result is achieved by a method for providing an activating influence on the functional state of the person by light radiation from the led light source according to the invention, exposure to white light of variable color temperature in the range C - 10000K exercise to open the eyes of the person registering the electroencephalogram, conduct its spectral analysis and reduction of the spectral power of alpha and theta rhythms more than 25% of the background values estimate the impact as the trigger.

Conducted investigation of effects on the functional state of the human brain dynamically managed ("intellectual") of light from a semiconductor source with a color temperature varied in the range from warm C to cold 10000K shades of white light.

Spectral analysis of EEG allowed to objectively evaluate changes in the basic rhythms of electrical activity in the brain when exposed to light with variable color temperature.

In the course of the study tested the prototype led mining light source controlled with the help of special software. The luminous flux of the light source depending on the color temperature was 1000-4000 LM. Color temperature of white light had changed and the mouth of the establishing in the range C - 10000K. The color rendering index for these color temperatures lying in the range of 80-90.

During the exposure of white light with various color temperatures were recorded electrical brain activity of the subject. The study involved 20 people ranging in age from 17 to 47 years (9 women, 11 men) with a mean age 28.55±3.23 years (here and below, after the average value is shown as the standard error).

The EEG recording was performed with an electroencephalograph "Telepathy-D" (, St. Petersburg) monopolar method according to the international system "10-20" points Fp1, Fp2, F3, F4, C3, C4, P3, P4, O1, O2, F7, F8, T3, T4, T5 and T6 by the indifferent electrodes placed on the earlobes. The sampling rate of the signals was 250 Hz, the bandwidth of the high frequency of 35 Hz, the time constant of 0.3 C.

As a control condition was used EEG with the eyes open. Next subject, remaining with open eyes, were subjected to sequential exposure to 5 choices of lighting, different preset color temperature of the led source. The duration of recording in the background and samples with different illumination corresponded to 2 min in each case, the intervals between exposures of light also had a duration of 2 minutes

The study obtained data was carried out visually and with the aid of the d spectral analysis. Determined values of the spectral power of alpha, theta, Delta and beta rhythms in all recorded areas of the cerebral cortex in all the stages of registration of brain activity. Spectral analysis was carried out using electroencephalographic program WinEEG Version 1.3". Epoch analysis in the calculation of the spectra was 4 C. the Average spectral indices were calculated for the entire duration of recording in the background and EEG during exposure to light samples.

When statistical processing of obtained results was calculated the average values of the analyzed characteristics, their standard deviation, standard error of the mean. Determination of the degree of reliability of the differences between averages were performed in the statistical software package Statistica 6" at the level of p<0.05 using Wilcoxon criterion.

Visual analysis of EEG dynamics during expositions of white light with variable color temperature showed the presence of mixed reactions in the group examined in the light from the led source. In some cases there was a visible decrease in the expression of alpha-rhythm with a tendency to transition from the constant activity to episodic outbreaks and irregular waves. On the basis of the described type reaction was allocated a group of 10 people (26.30±3.26 years, 6 women and 4 men) with primary weakening of the alpha rhythm.

In the group is determined by the tendency to decrease the power of the alpha rhythm in all samples, except for the exposure light with 4800 K. Under illumination with 10000K weakening of the spectral power of the alpha rhythm is the most prominent and reliable in a number of areas (p<0.05 in C3 and T5), while there is a moderate decrease in the power of theta rhythm (p<0.05 in Fp1, C4, P3, P4, O1, O2, F7, and T5). Any significant impact imposed on the light on the power of Delta - and beta-rhythms in the group can not be traced.

The General character of the changes in the EEG of the subject testifies to the activating effects of light. It is known that the suppression, oppression, power reduction of alpha activity without replacement of the slow waves are associated with higher levels of activation of the Central nervous system, increasing the level of wakefulness. Not only does not increase, and the weakening of theta rhythm confirms the activating effect of light on the subject in the group.

Method of providing an activating influence on the functional state of the person by light radiation from the led light source is illustrated by examples.

Example 1.

The subject I s, 20 years.

Were recorded EEG during eyes open as in a state of passive wakefulness, and when exposed to white light from an led source with a color temperature of K. Long is alnost exposure of 120 seconds. Calculated spectral power of alpha and theta rhythms.

The level of changes in the spectral power of EEG rhythms when exposed to light with respect to the initial state are given in Table. 1. All derivations level spectral power of the alpha rhythm has declined by more than 39%. The spectral power of theta rhythm has also declined in all regions more than 27%.

Thus, the light with a color temperature of 1700 To lower spectral power of alpha and theta rhythms more than 25%, indicating that the increase in the level of activation of the cerebral cortex. In General, the survey I-VA white light with C is activating.

Table 1
Changes in the spectral power of alpha and theta rhythm of the tested I-VA when exposed to light with a color temperature of K
Leadα-rhythmθ-rhythm% change
BackgroundLightBackgroundLightα-rhythmθ-rhythm
Fp148,8013,657,804,07-72,03-47,82
Fp244,5013,216,903,69-70,31-46,52
F348,8017,557,804,21-64,04-46,03
F446,3015,477,303,96-66,59-45,75
C348,7018,557,704,16-61,91-45,97
C446,5016,217,003,86-65,14-44,86
P350, 20mm30.37 per 10,806,03-39,50-44,17
P453,5030,836,90to 4.52-42,37-34,49
O176,7038,706,20as 4.02-49,54-35,16
O2130,6066,237,40to 4.41-49,29-40,41
F729,406,983,702,69-76,26-27,30
F8of 34.409,065,803,48-73,66-40,00
T322,508,844,002,20-60,71 -45,00
T423,309,905,202,39-57,51-54,04
T518,20of 10.934,202,30-39,95-45,24
T631,3014,843,602,39-52,59-33,61

Example 2.

Test T-VA, 21 years.

Were recorded EEG during eyes open as in a state of passive wakefulness, and when exposed to white light from an led source with a color temperature of 10000K. An exposure time of 120 C. was Calculated spectral power of alpha and theta rhythms.

The level of changes in the spectral power of EEG rhythms under the influence of the light relative to the background state with the eyes open is shown in Table. 2. All leads spectral power of the alpha rhythm has been reduced by more than 64%. In leads C3, C4, P3, O1, F7, T3, T5 spectral power of theta rhythm has also been reduced by more than 29%.

Based on the fact that snizeni the spectral power of the alpha rhythm was more than 25% in all areas, while the spectral power of theta rhythm in terms of derivations, we can talk about raising the level of activation of the cerebral cortex in response to light exposure with a color temperature of 10000 K, more pronounced in the left hemisphere. In General, for the subject of the T-th white light with 10000K is the trigger.

Table 2
Changes in the spectral power of alpha and theta rhythm test T-howl when exposed to light with a color temperature of 10000K
Leadα-rhythmθ-rhythm% change
BackgroundLightBackgroundLightα-rhythmθ-rhythm
Fp19,962,929,1210,37-70,6813,71

Fp210,153,12 9,138,78-69,26-3,83
F3of 13.273,19,72to 7.59-76,64-21,91
F412,323,518,888,09-71,51-8,90
C320,083,1510,816,69-84,31-38,11
C425,024,611,047,83-81,61-29,08
P339,25a 3.9a 12.03? 7.04 baby mortality-90,06-41,48
P436,185,1210,288,93-85,85 -13,13
O147,825,111,327,52-89,34-33,57
O259,57,6614.24 from11,35-87,13-20,29
F77,312,566,84,47-64,98-34,26
F85,551,744,815,10-68,656,03
T38,05to 2.066,26of 3.56-74,41-43,13
T45,561,494,274,16-73,20-2,58
T514,91 2,866,864,58-80,82-33,24
T621,193,294,595,73-84,47to 24.84

Spectral analysis of EEG allowed to objectively evaluate changes in the basic rhythms of electrical activity in the brain when exposed to light with variable color temperature.

Based on the obtained data we can conclude that when the exposure of white light with a color temperature in the range C - 10000K spectral analysis of the electroencephalogram showed that reduction of the spectral power of alpha and theta rhythms more than 25% of the background values conclude that light exposure increases the level of activation of the cerebral cortex and is the trigger.

The proposed method allows for individual selection of the color temperature in the range C - 10000K, providing an activating effect on the functional status of a person, when exposed to light radiation from the led source.

Method of providing an activating influence on the functional state of the person by light radiation from todiagnose source, characterized in that the exposure to white light of variable color temperature in the range of 1700 To - 10000 To carry out on the open eyes of the person, record the electroencephalogram, conduct its spectral analysis and reduction of the spectral power of alpha and theta rhythms more than 25% of the background values estimate the impact of both activating.



 

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1 ex, 6 tbl

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2 tbl, 1 dwg

FIELD: medicine.

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1 tbl, 2 ex

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1 tbl, 2 ex

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2 tbl, 2 ex

FIELD: medicine, neurology, psychopathology, neurosurgery, neurophysiology, experimental neurobiology.

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EFFECT: higher accuracy of diagnostics.

5 dwg, 1 ex, 1 tbl

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