Method of treating varicose disease of lower extremities with application of endovenous laser vein coagulation
SUBSTANCE: invention relates o medicine and can be applied in treating varicose disease of veins of lower extremities with application of endovenous laser vein coagulation (ELVC). For this purpose skin area, which is subjected to operation, is processed with antiseptic solution. Under control of ultrasonic apparatus into vessel lumen introduced is catheter, through which light-conductor is passed to saphenofemoral fistula. After that, tumescent anesthesia is performed by creation of water "cushion", at that applying cold, ozonised 0.9% physiological solution with temperature 5-7°C, ozone concentration 4-5 mcg/ml and time of saturation with ozone 5-8 minutes. Or ozonised 0.1% lidocaine solution with temperature 5-7°C, ozone concentration 4-5 mcg/ml and time of saturation with ozone 5-8 minutes is introduced. After that, pathological vessel is exposed to laser energy. If necessary, applications of 50 ml ozonised heparin-containing gel are made after procedure in projection of coagulated vein with exposition 60-90 minutes until ozone concentration of gels reaches 6500-7000 mcg/ml.
EFFECT: method ensures effective treatment of said pathology due to selection of most optimal type of anesthesia and following therapy, which contribute to reduction of pains, local manifestations of inflammation, activation of processes of focal and marginal epithelisation processes.
The invention relates to medicine, namely to the treatment of varicose disease of lower extremities using endovenous laser coagulation veins (MLC).
When the casualty operations, and chronic pain syndromes require anesthesia, such as conduction blockade on how modern component.
Conduction anesthesia, like any other medical procedure, is not without risk of complications. Depending on the type of procedure being performed and the localization of the nerve trunk complications may include: injury to adjacent blood vessels, nerve injury, infection of the puncture site, the toxic effects of local anaesthetics, allergic reactions to local anesthetics (http://www.esraeurope.org/, http://www.rusanesth.com/forum/) - .
Tumescent anesthesia is one of the important stages of MLK with varicose disease of lower extremities. Goal is to protect parabasal tissues and anatomical structures (lymphonodectomy, nerves)situated in the projection of coagulation trunk of one or another of Vienna, from damaging thermal effects.
Varicose veins is a pathology that is characterized by a thinning of the walls of veins, uneven expansion and the formation of specific nodes. Varicose veins are almost 27% of women, 15% men and is the most common vascular the disease. The most commonly affected vessels of the leg. Before her treatment was associated with surgical intervention.
Severe traumatic surgery in the past, and came the era of minimally invasive techniques. There is a method of treatment of varicose veins (varicose veins), easily portable and does not require the patient refuses the usual lifestyle is endovenous laser ablation (endovascular laser coagulation MLC (EVLK)), which is the technology of the XXI century. Treatment of varicose veins laser can successfully get rid of varicose veins, not off from life and work in normal mode. That is why laser coagulation was called "Office surgery" (www.club-spa.ru/evlk.html) - .
Treatment of varicose veins MLK performed under local anesthesia on an outpatient basis and takes about an hour. The area of skin subjected to a surgical procedure, treated with antiseptic solution. Using the ultrasonic device control the conduct of the catheter into the lumen of the vein. Through the catheter to the desired location passes the fiber, then the solution perform tumescent anesthesia, and laser energy begins to influence the pathological vessel. After the procedure, the patient's leg wear special operating elastic stockings.
During a session of laser photocoagulation using tumescent Annes is Ezio, in which the administration of anesthetic produced in parabasal fiber (around Vienna). It provides complete and quick pain relief. However, when the anaesthesia in the postoperative period patients have the appearance of bruises along the coagulated veins. The reason for the appearance of bruises lies in the perforations of Vienna at MLK and overly made tumescent anesthesia, when "crawling" infiltration under pressure breaks the subcutaneous tissue, in addition, on some remote time in the projection coagulated veins can occur pigmentation of the skin, the sense of "chord" along the thighs (about 20% of patients at 4-6 days after MLK can receive the pulling sensation along the coagulated veins, preventing the end to straighten the limb), as a rule, this feeling disappears at time 1.5-2 months, short-term temperature rise to subfebrile figures after conducting MLK. This temperature rise is due to pyrogenic action formed after EWLC products of protein degradation. All this reduces the effectiveness of the method of treatment of varicose disease of lower extremities using endovenous laser coagulation veins.
The technical result, which directed the claimed invention is to improve the quality of the implemented method for MF is t effective ongoing anesthesia, providing: subsequent more rapid recovery of the physiology of the surrounding tissues and the whole body due to the pain subsided, reducing the feeling of heaviness in the affected limb, burning and itching, reduction of local manifestations of inflammation, a gradual process of focal and epithelialization, in addition, improving the overall health of patients, stabilization pattern of lipid profile, activation of the antioxidant enzymatic system by using ozonated cold anesthetic.
The technical result is achieved in that the method of treatment of varicose disease of lower extremities using endovenous laser coagulation of the veins, by which the area of skin subjected to a surgical procedure, treated with antiseptic solution, an ultrasonic device to control the introduction into the vessel lumen of the catheter, through which conduct the light to the sapheno-femoral anastomosis, perform tumescent water cushion saline solution, after which the laser energy impinges on the pathological vessel, what is new is the fact that to create water "cushion" use cold ozonated of 0.9% saline solution, and the solution temperature is 5-7°C, the concentration of ozone 4-5 µg/ml, and the feeding of the ozone 5-8 minutes.
For reinforced what I analgesic effect when performing endovenous laser coagulation veins as physiological solution using ozonated 0.1% lidocaine solution with a temperature of 5-7°C, ozone concentration to 4-5 mg/ml and the time of saturation of ozone 5-8 minutes.
After the procedure in the projection coagulated veins perform the application of ozonized Eparistera gels, exposure time of 50 ml which is 60-90 minutes before reaching the ozone concentration gels 6500-7000 µg/ml.
Any disease begins and progresses in terms of violations peroxidation and ischemia, microvascular processes, and disorders of metabolism. It is known that ozone is a powerful oxidant: joining cells, it breaks on active oxygen and free radicals. Pathogenetic effect of ozone therapy is achieved through the accumulation of oxygen molecules. With ozone therapy can achieve recovery at the microsomal level. Ozone is used in the form of ozonated solutions, it restores oxygen transport, eliminates toxins, stimulates regeneration, bacteriostatic, bactericidal and antiviral effect, analgesic and anti-inflammatory effect, helps to restore adequate blood flow and metabolism, releases oxygen, normalizes metabolism, hormones, relieves toxicity, it will expand the vessels, improve microcirculation, has immunostimulant, antibacterial, antiviral and anti-inflammatory dei is a journey, prevents thrombus formation.
Cool the solution initially causes spasm of the blood vessels, which increases thermogenesis and stimulation of blood vessels, facilitates venous return. All this is very helpful rehabilitation after trauma to the surrounding tissue with laser energy.
The method of treatment of varicose veins using endovenous laser coagulation veins is as follows.
The area of skin subjected to a surgical procedure, treated with antiseptic solution, under control of the ultrasonic apparatus is introduced into the vessel lumen catheter, through which conduct the light to the sapheno-femoral anastomosis, perform tumescent water cushion saline solution, after which the laser energy impinges on the pathological vessel. To create water "cushion" use cold ozonated of 0.9% saline solution, and the solution temperature is 5-7°C, the concentration of ozone in solution 4-5 µg/ml, and the feeding of the ozone 5-8 minutes.
To enhance the analgesic effect when performing endovenous laser coagulation veins as a solution for anesthesia can be used ozonated 0.1% lidocaine solution with a temperature of 5-7°C, the ozone concentration to 4-5 mg/ml and the time of saturation of ozone 5-8 minutes.
After the procedure in the projection of COAG the isolation of the veins perform the application of ozonized Eparistera gels, exposure time of 50 ml which is 60-90 minutes, before reaching the ozone concentration gels 6500-7000 µg/ml.
At the end of the holding means at the patient's legs to put on a special operating elastic stockings.
Before anaesthesia ozoneresistant cold anesthetic prepared immediately before the procedure. For ozone using setup "MedozonsBM". What for 5-8 minutes, cooled sterile 0.1% solution of lidocaine or saline 0.9% in a tightly closed bottle 400 ml saturated with ozone-oxygen mixture until the desired ozone concentration to 4-5 mg/ml, the Temperature of the solution in the vial to achieve the goal should be from +5 to +7°C. Further, the area of skin subjected to a surgical procedure, treated with antiseptic solution. Ultrasound monitors the catheter, which is introduced through the skin into the lumen of the vessel. Through the catheter to the desired location passes the fiber is then performed tumescent anesthesia cold ozonated 0.1% solution of lidocaine or saline 0.9% parabasal fiber (around Vienna) 400-600 ml In the process of discharge is very clear, as the solution compresses the lumen of the vein before its complete closure. Around the trunk is formed circular "water pillow", which will allow absolutely bezbolez the NGOs to carry out laser coagulation of the lumen of the trunk of the great saphenous vein, without damaging adjacent soft tissue and nerve bundles, after anesthesia laser fiber pull outward while the laser energy affects the pathological vessel. After the procedure in the projection coagulated veins perform the application of ozonized Eparistera gels and legs of the patient is put on operational elastic stockings. The exposure time 50 ml Eparistera gels (Lioton gel", "Heparin ointment and the like) is 60-90 minutes and reaches concentrations of ozone 6500-7000 µg/ml.
Thus, used ozonated solution improves microcirculation and tissue oxygenation of the whole body, to optimise its oxygen homeostasis and causes the restructuring of compensatory reactions in pathology at different levels of the vascular system, which is manifested in the restoration of functions of the peripheral circulation due to start functioning collaterals, ensuring regional action all therapeutic properties of ozone. Cold, in addition, which increases thermogenesis and stimulation of blood vessels, facilitating venous return, cause a spasm of the vessel, subjecting the latter closer contact with the wall with the light guide, respectively, and with the laser energy, thereby leading to a more guaranteed absence of recanalization of the trunk that t is aetsa one of the reasons recanalization coupled with inadequate selection of used laser power at the time of execution of MLK. Positive dynamics in the patient's condition comes much earlier than with conventional anesthesia during MLK. So managed to avoid the development of a typical MLC complications such as redness, swelling, achimota, pastos. In addition, the use of ozonated Eparistera gels contributed to the rapid recovery of sensitivity when parastasi. The method of solution preparation and anesthesia simple, fairly cheap, can be used on an outpatient basis, and the carrying out of the method of treatment of varicose disease of lower extremities using endovenous laser coagulation veins generally provides faster recovery and return patients to a normal life, not requiring hospitalization in the surgical hospital, in addition, when a simple count of all treatment costs, MLK be more advantageous economically.
1. The method of treatment of varicose disease of lower extremities using endovenous laser coagulation of the veins, by which the area of skin subjected to a surgical procedure, treated with antiseptic solution, an ultrasonic device to control the introduction into the vessel lumen of the catheter, through which conduct the light to the sapheno-femoral anastomosis, perform tumescent water "cushion" the physiological the practical solution then the laser energy impinges on the pathological vessel, characterized in that to create tumescent water "cushion" use cold ozonated of 0.9% saline solution with the solution temperature 5-7°C, the ozone concentration to 4-5 mg/ml and the time of saturation of ozone 5-8 minutes or ozonated 0.1% lidocaine solution with a temperature of 5-7°C, the ozone concentration to 4-5 mg/ml and the time of saturation of ozone 5-8 minutes.
2. The method according to claim 1, characterized in that after the procedure in the projection coagulated veins perform the application of ozonized Eparistera gels, exposure time of 50 ml which is 60-90 minutes, before reaching the ozone concentration gels 6500-7000 µg/ml
SUBSTANCE: invention refers to medicine, namely to surgery, and concerns a multimodality therapy for diabetic foot. That is ensured by a local and infusion therapy. The local therapy involves using the ointments Curiosin and Levomecol. The infusion therapy involves administering rheopolyglucin 5.3 ml/kg and 2% trental 1.3 mg/kg, 0.9% NaCl 300 ml and Cytoflavin 10 ml; 0.9% NaCl 300 ml and vitamin C 9 mg/kg in daily doses for degree I ulcers; the infusion therapy is combined with a magnetic therapy generated by MAGNET-Med TeKo apparatus at magnetic induction intensity 75% for 16 minutes. Degree II ulcers require doses of the infusion preparations, except for 0.9% NaCl, to be doubled, while the magnetic therapy is performed at magnetic induction intensity 100%, length of exposure 32 minutes; the therapeutic course is 10 procedures.
EFFECT: method provides higher effectiveness and reduced length of treating ensured by the correction of oxidation-reduction processes and improvement of tissue regeneration.
SUBSTANCE: invention refers to derivatives of oxazolopyrimidine in any of their stereoisomeric forms, or in the form of a mixture of stereoisomeric forms specified in Claim 1.
EFFECT: oxazolopyrimidine derivatives having agonistic activity in relation to Edg-1 receptor.
5 tbl, 319 ex
SUBSTANCE: invention refers to medicine, namely to experimental cardiology, and concerns the L-NAME-induced endothelial dysfunction correction. That is ensured by introducing the mixture of solutions of homoeopathic dilutions of rabbit monoclonal antibodies to human endothelial nitrogen oxide synthase C12, C30, C200 (9 ml/kg/day) in complex with the mixture of solutions of homoeopathic dilutions of angiotensin II receptor C-terminal fragment antibodies C12, C30, C200 in a dose of 9 ml/kg/day.
EFFECT: method provides the effective endothelial dysfunction correction in the specific experimental environment.
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine, namely to cardiology, and concerns the endothelial dysfunction correction. That is ensured by a therapeutic agent containing an activated potentiating form of vascular endothelium growth factor (VEGF) antibodies. The activity of the therapeutic agent is related to the process of multiple serial dilutions in an aqueous or aqueous-alcohol solution in a combination with an external mechanical vertical agitation of each dilution.
EFFECT: method provides the effective L-NAME-induced endothelial dysfunction correction in experiment.
6 cl, 1 ex, 1 tbl
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutical industry, particularly to therapeutic preparations of mumiyo. The therapeutic preparation which contains purified mumiyo, grapefruit citrosept, edible glycerol, ethanol and water at specific proportions.
EFFECT: preparation has a prolonged shelf life.
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutical industry, particularly to a composition and a combination for treating panniculopathy and problems associated with venous insufficiency of the lower limbs. The composition for treating panniculopathy and problems associated with venous insufficiency of the lower limbs, containing esculoside and at least one compound selected from icarine or its derivatives, or extracts containing it (them), Gingko biloba dimer flavones in a free form or complexed with phospholipids, amentoflavone and at least one compound selected from escin, escin beta sitosterol complexed with phospholipids, sericoside, sericoside complexed with phospholipids, or Centella asiatica extract in a free form or complexed with phospholipids. The use of the combination on the basis of the mentioned ingredients for preparing the composition for treating panniculopathy and problems associated with venous insufficiency of the lower limbs.
EFFECT: above-described composition and combination are effective in reducing panniculopathy and problems associated with venous insufficiency of the lower limbs.
SUBSTANCE: invention refers to medicine, namely angiology, intensive care, cardiovascular surgery and phlebology, and may be used for integrated treatment of acute thromboembolia of pulmonary artery. That is ensured by prescribing anticoagulants, disaggregants, antibiotic therapy added by thrombolytic therapy by the oral introduction of the preparation Thrombovasim 0.02 mg/kg combined with deobliteration of pulmonary artery or pulmonary trunk by direct surgical thromboembolectomy in complete bypass with retrograde perfusion of pulmonary arteries. Treatment of acute thromboembolia is added by prescribing the preparation Vasaprostan* 60 mcg daily intravenously starting from the moment of diagnosing and up to 7 postoperative days.
EFFECT: method provides higher clinical effectiveness in the patients and preventing developing complications ensured by correction of main pathological links of developing complications of acute thromboembolia of pulmonary artery.
FIELD: medicine, pharmaceutics.
SUBSTANCE: what is presented is the new chemical compound - a 3-(2,2,2-trimethylhydrazinium)propionate derivative - 3-(2,2,2-trimethylhydrazinium)potassium propionate glycinate, (CH3)3N+NHCH2CH2COOKRCOO-, wherein exhibiting endothelioprotective activity. The presented derivative can find application in medicine in the integrated treatment for endothelial dysfunction correction in cardiovascular diseases.
EFFECT: enhanced endothelioprotective properties as compared with previously known mildronat due to the introduction of new functional group showing the most manifested antioxidant properties.
SUBSTANCE: there are conducted crossectomy, direct and/or indirect thrombectomy, ligation of inadequate perforating veins and varicose flows of subcutaneous vein stems. A pathological venous bed is eliminated by endovasal laser coagulation (EVLC) of the inadequate subcutaneous vein stems. The surgical procedure is performed under tumescent anaesthesia of the EVLC region by physiologic saline cooled to 6-7°C at ozone concentration 4-5 mcg/ml. It is assisted by continuous ultrasonic navigation. The EVLC region involved in varicothrombophlebitis and the incisional wound are processed by argon-plasma flow followed by elastic compression of the operated extremity.
EFFECT: method extends the range of product for treating acute varicothrombophlebitis of the lower extremities.
SUBSTANCE: gestosis model in Wistar rats is reproduced by the daily intraperitoneal introduction of L-nitro-arginine-methyl ester 25 mg/kg for 14th to 20th day of pregnancy. The simulated pathology is corrected by the subcutaneous introduction of recombinant erythropoietin 50 IU/kg on the 7th, 10th, 13th, 16th, 19th day of pregnancy.
EFFECT: method provides evident placental microcirculation correction.
SUBSTANCE: photosensitiser Photosense is administered. The patient is irradiated with using an optical fibre with a lens on a distal end in contact with a chest wall along intercostal spaces in 8-10 random positions for 1 therapeutic session. A light dose of one position of the laser radiation is 100 J, and an output power is 200-250 mWt,.
EFFECT: method provides regression of the tumoural process, obliteration of the pleural cavity without the aggressive intrapleural intervention, and eliminates potential infections.
SUBSTANCE: with underlying antiviral therapy, blood is exposed intravenously to wave length 365 nm first, emission power 2 mWt, exposure 2 minutes. On the next day - at wave length 530 nm, emission power 2 mWt, exposure 8 minutes. There are 15 sessions of intravenous laser blood irradiation prescribed.
EFFECT: terminated reactivation of urogenital cytomegaloviral infection, reduced length of the following recurrent cases, prolongs an intercurrent period and promotes the clinical course of the viral infectious process transformed into a persistence ensured by stimulation of an inadequate immune response, normalises the interferon status and suppression of the hyperactive processes.
SUBSTANCE: starch or sorbite photosensitiser powder is administered into a laryngeal pharynx that is further exposed to laser light. The laser light exposure is performed at wave length 0.685 mcm, powder 18-20 mWt, energy density 18-28.8 J/cm2.
EFFECT: implementing the method provides the reliable laryngeal fixation of the photosensitiser, maintains the constant concentration of the photosensitiser for the whole therapeutic session, and thereby faster reduction of the inflammatory process.
2 cl, 4 ex
SUBSTANCE: method involves reflex therapy (RT) alternated with taking general baths every second day. The RT is conducted by inserting needles into corporeal points and microneedles into auricular points of the systemic effect on the 1, 5, 9, 13, 17, 21 procedures and executing the electric acupuncture of the paravertebral points on the 3, 7, 11, 15, 19 and 23 procedures. If the patients shows predominating psychoasthenic symptoms, iodine bromine baths are taken. The baths contains potassium iodide 50 mg/l and potassium bromide 125 mg/l. Water temperature is 36-37°C. If the vegetative imbalance predominates in the patients, radon baths with the radon concentration of 40-80 nCu/l are taken. Water temperature is 26-28°C. That is combined with the following laser therapy. The laser therapy is generated by Mlada apparatus. What is used is a continuous infrared light at wavelength 0.85 mcm, total output power of the two emitters 30 mWt. The patient is exposed by the standard procedure. The exposure covers 4 fields: a collar, an apex of heart, a middle one-third of chest and a left infrascapular region. The exposure length is 1 minute from 1st to 3rd procedure, 2 minutes from 4th to 6th procedures, and 3 minutes starting from the 7th procedure.
EFFECT: method improves the psychoemotional state of the patients thereby normalising the vegetative balance, and improves the working efficiency.
SUBSTANCE: invention refers to medicine, particularly to paediatrics, namely to otorhinolaryngology, and may be used in treating chronic tonsillitis in children's health centres, in-patient hospitals, polyclinics. The low-power laser light covers projections of palantine tonsils, namely an anterior lateral neck surface below a mandibular angle to the right and to the left. The laser light is generated at wavelength 0.89 mcm, constantly variable frequency 10 to 1,500 Hz by AZOR 2K-02 apparatus in the contact, stable mode. The exposure length is 1 minute per a field at pulse power 2-3 Wt/pulse daily; the therapeutic course is 7-8 procedures in 5-10-year-old children. The exposure takes 2 minutes per a field at pulse power 4-5 Wt/pulse daily within the therapeutic course making 9-10 procedures. Each physiotherapeutic procedure is preceded by tonsillar lacunae irrigation with sterile 0.9% normal saline using a Hartmann cannula. The method is safe by selecting laser light conditions in the children of various age groups.
EFFECT: method enables higher clinical effectiveness in chronic tonsillitis, prolonging remission, reducing a recurrence and complication rate, lowering the need for medical treatment, improving the quality of life in children and adolescents.
SUBSTANCE: invention refers to medical equipment, namely to prostate exposure apparatuses. The prostate exposure apparatus comprises a bevelled end hollow cylindrical body for the contact of its tip with an exposure area; the tip of the apparatus adjoins a laser source, a heating element, a temperature sensing element, an active electrode, and an indifferent electrode, an electronic unit, an inductor coil, and an ultrasonic assembly representing a piezoelectric radiator with an ultrasound concentrator in the form of a metal core that is an active electrode simultaneously; one end of the active electrode is led on the tip of the apparatus, while the other end is mechanically coupled with the piezoelectric radiator and connected to the electronic unit; the indifferent electrode also connected to the electronic unit is brought out of the body, while the inductor coil is configured so that the active electrode extends along an axis of symmetry; the piezoelectric radiator, targeted laser source, heating element, temperature sensing element and inductor coil are connected to the electronic unit.
EFFECT: due to the inductor coil and ultrasound emitter, the apparatus as compared to its prototype enables additional ultrasonic and magnetic field exposure on the prostate that improves the therapeutic effectiveness.
SUBSTANCE: invention refers to medicine, namely medicine, and may be used for treating urethral syndrome in females with using the antibacterial preparation gentamycin. Gentamycin is introduced into a urethral wall in the amount of 80 mg dissolved in anaesthetic solution 2 ml. The above preparation is introduced in parallel with the urethral wall. The anaesthetic is presented by 0.25% Novocaine. That is followed by a vulvar exposure to an infrared laser light at wave length 0.82 mcm, frequency 3000 Hz, and power 10 mWt. A procedure length makes 5-6 minutes; the therapeutic course is 8-10 procedures.
EFFECT: method is well tolerated, accessible and high effective by providing the high gentamycin concentration in the area of inflammation and stimulating repair processes.
1 ex, 2 tbl, 1 dwg
SUBSTANCE: group of inventions refers to medicine, treating a cervical pathology associated with a high-oncogenicity human papilloma virus (HPV) infection. To eliminate the HPV for the purpose of the prevention of cervical cancer, a cervical mucosa is coated with a layer of a carbon dye and exposed to a laser light. What is used is a pulse-periodic generation mode having the following parameters: power flow density 2-10 J/cm2, radiation pulse duration 10-4 -10-2 sec, pulse repetition rate 1-5 Hz, wave length 0.8-1.1 mcm. A device for implementing the method comprises a laser working in the above mode with the above parameters, a modulator, a control and indication unit for laser parameter setting by the modulator, a parameter measurement unit for laser control, a controlled microinjector, a carbon dye delivery and radiation system actuated by the controlled microinjector, a probing laser for controlling the carbon dye layer thickness.
EFFECT: group of inventions provides eliminating the HPV from the cervical surface, controlling the thermal exposure area, its safety with avoiding an uncontrolled, irreversible injury of the cervical surface and the uterine itself.
8 cl, 1 dwg, 5 ex
SUBSTANCE: invention relates to medicine, particularly to ophthalmology. What is involved is a brachytherapy of an intraocular melanoma with a size of more than 6.5 mm by anchoring a beta-applicator with ruthenium-106 +rhodium-106 to an episclera for 7-14 days on a projection of the melanoma at total radiation dosage 3000 Gy. The brachytherapy is combined with a diode-laser transpupillar therapy of the melanoma at radiation power 800 mWt. Then, 6-12 months after the beta-applicator has been removed, a restrictive retinal coagulation at power 500 mWt and an endoresection of the residual melanoma follow. The method enables avoiding such complications, as vitreous body and retina haemorrhage, retinal detachment, complete loss of vision, as well as reducing a probability of metastases due to the preliminary brachytherapy and the following restrictive retinal laser coagulation.
EFFECT: combined application of the thermal therapy and brachytherapy enables affecting the melanoma from both sides for more complete destruction of its structure.
SUBSTANCE: invention refers to medicine, namely gynaecology, physiotherapy. A method involves the integrated treatment of the patients with genital endometriosis and hysteromyoma. The treatment involves taking mineral water, observing a biologically programmed light pattern, taking radon baths and radon gynaecological irrigations and small enemas, as well as conducting a laser therapy of biologically active points (BAPs). The patients take carbonated chloride-hydrocarbonate-sulphate sodium-calcium warm Narzan water taken from sources No. 4, No. 7 and No. 24, 3.4 mg per kg 3 times ad day, 40 minutes before meals. The radon baths are taken with the radon concentration of 1.5 kBq/l. The radon gynaecological irrigations and microenemas are performed with the radon concentration of 6.5 kBq/l, temperature 36°C, for 15 minutes within the course of 10-12 procedures. The BAP laser therapy is conducted in an autoresonant mode. The BAPs of anterior median meridian are covered, including: 1-2 (qu-gu), 1-3 (zhong-ji), 1-4 (guan-yuan), 1-5 (shi-men), 1-7 (yin-jiao); renal meridian: R-12 (da-ho), R-13 (qi-xu), R-14 (si-man), R-15 (zhong-zhu), R-16 (huang-shu); bladder meridian: V-31 (shang-liao), V-32 (ci-liao), V-33 (zhong-liao), V-34 (xia-liao); posterior median meridian: T-2 (yao-shu), T-3 (yao-yang-guan), T-4 (min-man), T-5 (xuan-shu). Using the radon baths of the different radon concentrations 'softens' an effect of the absorbed radiation dose on the homeostasis systems and preserves an effect of a high absorbed dose on the genital system. The laser therapy in the autoresonant mode within pathological BAPs improves the accuracy of the exposure on the pathological processes within a target organs.
EFFECT: method prolongs the remission, normalises the hormonal ratios in the remote period.
2 dwg, 4 ex
SUBSTANCE: group of inventions relates to medical equipment. A device comprises a fluid duct with one or more microparticles and a joint integrated in the duct. The fluid flow within the joint is adjusted with a field of force. Another version of the device comprises a nozzle providing fluid flow passage through a dead leg adjoining the joint to make the microparticles escaping from the dead leg. The method involves injection of fluid with one or more radioactive microparticles into the duct comprising the joint, and adjustment of the fluid flow within the joint with the field of force. When delivering one or more substantially spherical microparticles to a subject, at least 90% of radioactive microparticles are introduced. Another version of the method involves a high-density microparticle source of high specific activity connected to a subject and the high-density microparticles of high specific activity to be delivered to the subject under source pressure in the range of 35 kPa to 207 kPa. Besides, one more version of the method implies imaging of one or more spherical microparticles for the purpose of data visualisation; and the visualised data are analysed to determine the abnormal condition.
EFFECT: application of said group of inventions enables effective drug microparticle target delivery by the vascular system.
34 cl, 7 dwg