Medical fixation device
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to chemical-pharmaceutical industry and medical equipment and may be used in preparing multifunctional biological active structures for the fixation of dressings and objects. The fixation device consists of a paper carrier made of cellulose and viscous fibres impregnated with a special preparation, dried; with its one side of the prepared carrier coated with an adhesive and with its other side coated with a primer and an adhesive.
EFFECT: improved drape effect, enhancement, easier and faster usage.
6 cl, 1 tbl, 2 ex
The invention relates to the chemical and pharmaceutical industries and can be used in the manufacture of multifunctional bioactive structures for fixing dressing devices and objects.
Higher technical indicators suggest means when using it compared to known Standards and THE similar in purpose means are achieved by the fact that medical use of the fixing means of a base paper weighing 25-40 g/m2containing cellulose and viscose fibers and acrylic component Acronal S537S in the number of 12-15 g/m2basics, where on one side the basics done first layer of primer coating weight of 3-4 g/m2and a second layer of acrylic adhesive coating weight 25-35 g/m2on the opposite side of the applied adhesive coating weight of 5-6 g/m2basics. The basis contains cellulose and viscose fibers with an equal number of them, the acrylic component is injected into the base paper by impregnation of 10%Acronal latex S537S and drying, the primer coating is produced by applying on a base paper 15%Acronal latex S537S added in include nanocellulose in the amount of 0.5% (based on solids of the latex and thickener in the form of Na-carboxymethylcellulose "Blanose 7H9C2" and its drying, the adhesive coating floor is given by the application of a primer coating of a mixture of acrylic emulsions AK-256 and Rosina in their mass ratio of 70:30 with added ammonia and thickener "Collacral VAL" and its drying, and antiadhesive coating is produced by applying on the basis of the fluoropolymer latex "Elavtor 7000" added the thickener in the form of Na-carboxymethylcellulose "Blanose 7H9C2" and its drying.
Paper, containing in its composition viscose fiber, has good drape and, accordingly, a high degree of adhesion means to the skin.
Add nanocellulose in acrylic latex Acronal S537S improves the rheological characteristics and, consequently, improves the quality of the primer with a small mass.
The tool is made as follows. On the paper machine to prepare a paper base containing equal amounts of cellulose and viscose fibers. Prepared acrylic emulsion with specified concentrations and compositions for impregnation basis, applying primer and adhesive layers, the composition for a release layer.
On a special machine in a continuous mode, a paper base impregnated with latex Acronal S537S with a concentration of 10% in terms of dry substance, given its expense and at a temperature of 125-140°C dried it. Then on one side of the applied primer coating by applying a specified number of Acronal latex S537S with a concentration of 15% plus the include nanocellulose in the amount of 0.5% (based on solids of the latex and zagustitel the m in the form of Na-CMC brand "Blanose 7H9C2" and the paper is dried at a temperature of 125-140°C. Then on the back put the antiadhesive coating by applying a specified number of latex PTFE-based "Elavtor 7000" added the thickener in the form of Na-CMC brand "Blanose 7H9C2 and dried paper at a temperature of 125-140°C. In a subsequent operation on the side with a primer coating is applied release coating by applying a given amount of the mixture of acrylic emulsions AK-256 and Rosina in their mass ratio of 70:30 with added ammonia and thickener "Collacral VAL", the paper is dried at a temperature of 100-110°C. Receive the finished product in the form of a roll. It serves for cutting with the receiving coils of a given width and length of the tape in each roll.
Example 1. Of a mixture of equal amounts of cellulose and viscose fibers cast a paper basis weight of 25 g/m2. It is impregnated with 10%Acronal latex S537S when the flow rate of dry matter 12 g/m2basis, dried at 125°C to constant weight. Then on one side processed basis to obtain a primer coating is applied Acronal latex S537S added in include nanocellulose and thickener in its consumption of dry matter 3 g/m2, dry basis and on the other side, apply the emulsion composition "Elavtor 7000 when the flow rate of 6 g/m2on the dry substance, again dried paper at 140°C and receive ant the adhesive coating. Then onto the paper side of the primer applied adhesive coating weight of 25 g/m2the paper is dried at a temperature of 100°C and receive the finished product.
Example 2. Unlike example 1, take a paper basis weight of 40 g/m2soaks her Acronal latex S537S when the flow rate of 15 g/m2based dried at 140°C, applied primer coating weight of 4 g/m2, it is dried at 140°C, on the other side of the framework is applied release coating weight of 5 g/m2, it is dried at 125°C, is applied from the side of the primer coating adhesive coating weight of 35 g/m2, it is dried at 110°C and receive the finished product.
Samples of the locking means are experiencing in accordance with state Standards.
The table shows the results of the tests.
The proposed locking tool can be used to close surgical wounds, minor cuts, abrasions and other household RAS, fixation bandages, needles, catheters, drainage tubes, etc.
Consumers offer funds may be health care, service, Ministry of emergency situations and civil defence, population.
|Physico-chemical characteristics of the obtained material|
|The quality metric of the received material||Example 1||Example 2||Values on state Standards and specifications|
|1. The weight of the adhesive layer with an area of 1 m2g||25||35||-|
|2. The resistance to peeling of the adhesive layer of material from a metal, N/m, on THE other 9393-196-00281022||190,0||of 225.6||175-225|
|3. The resistance to peeling of the adhesive layer of the material from the back side, N/m, on THE other 9393-196-00281022-2001||92,0||120,0||25-150|
|4. The resistance to peeling of the adhesive layer from intact skin, N/m, R 53498-2009||74,5||110,3||50-200|
|5. Water vapor permeability, mg/cm × h, R 53498-2009||5,9||a 3.9||At least 1.5|
|6. Elongation, %, GOST 13525.1:|
|- in the machine direction||8,9||8,1||-|
|in the transverse direction||13,5||13,0||-|
1. Medical the locking means of the base paper weighing 25-40 g/m2containing cellulose and viscose fibers and acrylic component Acronal S537S in the number of 12-15 g/m2basics, where on one side the basics done first layer of primer coating weight of 3-4 g/m2and a second layer of acrylic adhesive coating weight 25-35 g/m2on the opposite side of the applied adhesive coating weight of 5-6 g/m2basis.
2. The tool according to claim 1, characterized in that the core contains cellulose and viscose fibers with an equal number of them.
3. The tool according to claim 1, wherein the acrylic component is injected into the base paper by impregnation of 10%Acronal latex S537S and drying.
4. The tool according to claim 1, characterized in that the primer coating is produced by applying on a base paper 15%Acronal latex S537S added in include nanocellulose in the amount of 0.5% (based on solids of the latex and thickener in the form of Na-carboxymethylcellulose "Blanose 7H9C2" and its drying.
5. The tool according to claim 1, characterized in that the adhesive coating are applied on the primer coating mixture is Kirilovich emulsions AK-256 and Rosina in their mass ratio of 70:30 with added ammonia and thickener "Collacral VAL" and its drying.
6. The tool according to claim 1, characterized in that the anti-adhesive coating is produced by applying on the basis of the fluoropolymer latex "Elavtor 7000" added the thickener in the form of Na-carboxymethylcellulose "Blanose 7H9C2" and its drying.
SUBSTANCE: invention relates to medicine, namely to traumatology and orthopedics, and can be used for prevention of purulent-inflammatory complications from application of apparatuses of external fixation in the process of treatment of patients in traumatology and orthopedics. For this purpose transosseous osteosynthesis of long tubular bones is performed by introduction of wires and intraosseous rods of compression-distraction apparatus of external fixation into their proximal and distal fragments. Antimicrobial substance is applied on the surface of wires and intraosseous rods before their introduction into proximal and distal fragments, as well as on degreased surface of patient's skin in places of entrance and exit of wires and intraosseous rods. As antimicrobial means used is gel-like nanostructured composite implant. It is replaced on degreased surface of skin in places of entrance and exit of wires and intraosseous rods 2-4 weeks after initial application. Composite implant includes platelet-enriched autoplasma, mixed in ratio 1:1.0-2.0 with granules of complex alloplastic preparation on the basis of hydroxyapatite, which contains 50-60 wt % of collagen. Said complex alloplastic preparation additionally contains 0.08-2.8 wt % of colloid solution of zerovalent metal silver Ag0, or gold Au0, or copper Cu0, or palladium Pd0, or platinum Pt0, which is introduced into its granules at preparation stage. Size of introduced colloid zerovalent metal nanoparticles constitutes from 2 nm to 40 nm.
EFFECT: method ensures efficient prevention of purulent-inflammatory complications in such patients due to elimination of microbial risk of bacterial contaminations in treatment of patients by means of apparatuses of external fixation.
5 cl, 5 ex
SUBSTANCE: invention relates to traumatology and orthopedics and can be applied for surgical treatment for deforming arthritis of ankle joint. Cartilages are ablated from joint surfaces of shin tibia and talus. Cut of skin is performed on external surface in the area of injured ankle joint on posterior edge of external ankle-bone. After exposure of fibula from lower third to its top at the level of joint space of ankle joint oblique osteotomy of fibula is performed above anterior and posterior tibial-fibular and calcaneal-fibular ligaments at 40-50° angle to its longitudinal axis. Anterior and posterior tibial-fibular and calcaneal-fibular ligaments are transversely dissected to 1/3-1/2 of their width. Volume of space formed between joint arthrodised surfaces of tibia and talus is filled with gel-like nanostructured composite implant, which contains platelet-enriched autoplasma in ratio 1:(1-2) with granules of complex alloplastic preparation, based on hydroxyapatite, containing 50-60% of collagen.
EFFECT: method makes it possible to improve possibilities of bone regeneration stimulation.
4 cl, 3 ex
SUBSTANCE: method involves evaporating a target of starting material with a pulsed electron beam with energy of not more than 100 keV, pulse duration of 20-300 mcs, energy density of not less than 1 MJ/cm2; a beam of electrons on the path to the target is passed through a system of generating a gas pressure drop, through which pressure of 1-20 Pa is provided in the evaporation chamber in order to cool particles, wherein particles are deposited on cooled substrates made of metal whose melting point is higher than 900°C, and the coefficient of linear thermal expansion is close to that of the deposited layer of aluminium oxide, the thickness of which is controlled in the range of 5-40 mcm by deposition time of 5-20 minutes, and radiation sensitivity is controlled by final heat treatment in the range of 550-900°C for 10-20 minutes.
EFFECT: high accuracy and reliability of detecting doses of short-range charged particles of nuclear radiations, including complex fields using TL or OSL techniques.
SUBSTANCE: method involves obtaining a biocompatible coating on dental implants made of titanium and alloys thereof, which involves placing articles into an aqueous electrolyte solution containing potassium hydroxide and nanostructured hydroxyapatite in form of an aqueous colloidal solution, and exciting micro-arc discharges on the surface of the articles. The treated articles are oxidised in a chemical-resistant non-conducting bath: two batches of treated articles are simultaneously placed in the electrolyte solution by pre-attaching articles of one batch to terminals for treated articles, and articles of the other batch to terminals of an auxiliary electrode; and the electrolyte further contains sodium hydroxide, sodium hydrophosphate, liquid sodium glass, sodium metasilicate, in the following ratios, with respect to mass of dry substance in g/l of the composition: potassium hydroxide KOH - 2, sodium hydroxide NaOH - 1, sodium hydrophosphate Na2HPO4×12H2O - 5, liquid glass nNa2O·mSiO2 (M=3.2) - 5, sodium metasilicate Na2SiO3×9H2O - 8, nano-dispersed hydroxyapatite - 0.5-5. Deviation from said concentrations of electrolyte components does not exceed ±10%.
EFFECT: improved method.
1 tbl, 4 dwg, 1 ex
SUBSTANCE: composition for making sensor coatings contains antimony-doped tin dioxide of the formula SbxSn1-xO2, where x=0.1-0.3, and water in ratio SbxSn1-xO2:H2O = 89-87:11-13 wt %. The method of preparing the composition involves hydrothermal treatment of tin and antimony hydroxides at 170°C for 48 hours. The tin and antimony hydroxides are obtained by dissolving Sn and Sb metal in concentrated hydrochloric acid, 18-20 wt %, while adding 3-5 wt % concentrated HNO3. The obtained solution is 2-3 times diluted with distilled water and a calculated amount of ammonia solution is added. Using a simple scheme, the disclosed method enables to obtain nanoparticles of said composition SbxSn1-xO2 with size of 30 nm and surface area of 154 m2/g, which can be used as the basic component of electroconductive ink for printing sensor arrays and microcontacts.
EFFECT: low labour and power consumption.
3 cl, 6 dwg, 3 ex
SUBSTANCE: invention can be used in magnetic nanoelectronics for magnetic registering media with high recording density, for magnetic sensors, radio-absorbing screens, as well as in medicine. Method of obtaining magnetite nanoparticles, stabilised with polyvinyl alcohol, includes obtaining magnetite in alkali medium of mixture of salts of bi- and trivalent iron and polyvinyl alcohol with weight content in initial mixture from 4 to 18 wt %, dispersion, washing and carrying out all operations under continuous ultrasound impact. Process of sedimentation of salts of bi- and trivalent iron and polyvinyl alcohol is carried out in ammonia vapour, with application of aqueous ammonia (NH4OH) or hydrazine hydrate (N2H4·H2O).
EFFECT: invention makes it possible to reduce scatter of magnetite nanoparticles by size, reduce labour consumption and expenditures in the course of process.
2 dwg, 2 ex
SUBSTANCE: invention relates to field of catalysis. Described is catalyst for recycling heavy oil fractions, in which active component, selected from nickel, or cobalt, or molybdenum, or tungsten compounds, or any their combination, is applied on inorganic porous carrier, consisting of aluminium oxide, dioxides of silicon, titanium or zirconium, alumosilicates or iron silicates, or any their combination, characterised by the fact that said catalyst contains macrospores, which form regular spatial macropore structure, and portion of macropores with size more than 50 nm constitutes not less than 30% in total specific volume of said catalyst pores.
EFFECT: increase of catalyst activity.
4 cl, 3 dwg, 1 tbl, 7 ex
SUBSTANCE: invention refers to medicine, namely to experimental studies in oncology and may be used for assessing the anti-tumour action of metal nanoparticles (NP). An iron nanoparticle suspension 1.25 mg/kg is introduced into grafted Pliss lymphosarcoma intratumourally. That is followed by the paratumoural introduction of methotrexate 0.2 mg/kg. The tumour is locally heated to temperature 42-43°C using an electromagnetic UHF emission at frequency 12.7 MHz for 10 minutes. The therapy requires 5 such sessions in total every 48 hours. That is followed by calculating an effectiveness index, a complete regression percentage and Pliss lymphosarcoma growth inhibition percentage.
EFFECT: method intensifies the antitumor effect of the thermal chemotherapy without increasing body toxicity.
FIELD: physics, optics.
SUBSTANCE: invention can be used in designing efficient devices for displaying alpha-numeric and graphic information. The increasing amount of visual information and advances in computer engineering require new-generation alpha-numeric displays. Disclosed is a quantum dot organic light-emitting diode with a monolayer of semiconductor quantum dots, lying at a distance from electron-conducting and hole-conducting layers, defined by an expression which links the Forster radius and the quantum dot radius. The active element is a monolayer of two-component (core-cladding) semiconductor nanoparticles capable of changing the diameter of the semiconductor core in the range of 2.0-6.0 nm and the thickness of the semiconductor cladding in the range of 1.0-3.0 nm in order to adjust the emission region in the range of 400-650 nm of the visible spectrum.
EFFECT: designing stable organic light-emitting diodes with the highest efficiency from the perspective of transmission of excitation energy from the donor to the active layer, said diodes having a controlled radiation spectrum in the visible wavelength range, which is crucial when designing new-generation alpha-numeric displays.
2 dwg, 1 tbl
SUBSTANCE: invention relates to production of organofilled polymer compositions and can be used in production of construction materials and in other sectors of the economy. The first version of the method of production involves grinding 10-90 wt % organic filler to particle size of 1-20000 mcm. The organic filler is then dried to moisture content of 0-50 wt % and mixed target additives in amount of 0-20 wt %. Components are then mixed with a high-molecular weight compound in amount of 10-90 wt % and a modifying additive is added in form of nanoparticles in amount of 0.0001-50 wt %, after granulation of the composition, to the whole mass of the obtained granulate by dry charging. The second version of the method of producing the polymer composition differs from the first version in that when modifying the polymer composition based on the organic filler, the granulate is added with an amount of the modifying additive in form of nanoparticles of up to 50% to the obtained composition at the compounding step.
EFFECT: invention shortens duration of the process and reduces labour input of production and cost.
2 cl, 5 ex
SUBSTANCE: what is presented is a boric coating containing a barrier material and an adhesive material. The barrier material and adhesive material are applicable for combined or sequential postoperative application on the mucosal tissue. Such application provides a multilayer film dressing containing a layer of the above barrier material and a layer of the above adhesive material contacting with the barrier material and mucosal tissue. The dressing is left unmoved in place for 48 hours after the postoperative application of the multilayer film on the mucosal tissue. The dressing is absorbed for 14 days. The multilayer film dressing has an external rim surrounding a tonsil bed and a concave centre shaped after the tonsil bed.
EFFECT: reducing or eliminating pain sensations following the mucosal operations, including tonsilectomy, adenoidectomy or other pharyngeal operations.
19 cl, 17 dwg, 3 ex
SUBSTANCE: disclosed is a respirator, having a laminate capable of reversible adhesion to human skin, having a substrate; an organosilicon mixture attached to the substrate; and an organosilicon adhesive film attached to the organosilicon mixture. The organosilicon mixture is essentially homogeneous and contains a hot-melt organosilicon adhesive with high adhesive power such as Bio-PSA-7-4560, which is solid at room temperature, and a low adhesive power organosilicon adhesive such as Bio-PSA-7-4101, which is a liquid low adhesive power organosilicon material. Also disclosed is a version of the respirator and method of making said respirator.
EFFECT: enabling reversible adhesion of the article to the skin of the user and reliable bonding of the base of the article and the organosilicon mixture.
9 cl, 3 tbl, 6 ex
SUBSTANCE: invention refers to medicine. What is described is an adhesion cover comprising a body of the adhesion cover with its substrate and adhesion layer on the substrate, wherein the body of the adhesion cover comprises a periphery, a centre and an intermediate portion between the periphery and the centre with the intermediate portion of the body of the adhesion cover having a thickness greater than that of the centre the body of the adhesion cover and the centre of the body of the adhesion cover having a thickness greater than that of the periphery of the body of the adhesion cover; what is also presented is a method for making it. The cover has the adhesion layer retaining its original shape.
EFFECT: improved usability.
10 cl, 1 tbl, 8 ex
SUBSTANCE: invention refers to medicine. What is described is an adhesion cover having a substrate, and an adhesion cover formed at least on one surface of the substrate, wherein the adhesion cover has a periphery and a centre; the adhesion layer has voids; the voids in the adhesion layer are localised in the periphery; the adhesion layer in the centre substantially has no voids, while the periphery of the adhesion layer preferentially comprises the voids in the average number of 2.0 to 100 voids/mm3.
EFFECT: adhesion cover is highly resistant to skin separation; there is no easy protrusion of the component of the adhesion layer from an edge of the adhesion cover when stored in a package; inhibited adhesion of the adhesion cover to the inner surface of the package; the adhesion cover can be easily removed from the package and avoided rise of the edges of the adhesion cover caused by cold plastic flow during adhesion to skin.
8 cl, 6 dwg, 1 tbl, 4 ex
SUBSTANCE: invention refers to medicine. What is described is a surgical barrier which includes a wound-facing polymeric coating comprising an enteric polymer, and at least one flexible substrate wherein at least one mentioned flexible substrate having at least one exterior surface with said polymeric coating is applied on at least one mentioned flexible substrate so that substantially cover at least one exterior surface thereof. There are also described a method for inhibiting the formation of adhesions in a patient who has undergone a surgical procedure, and a method for repairing a gastric or duodenal perforation.
EFFECT: reduced probability or prevention of the formation of adhesions associated with the surgical intervention.
27 cl, 4 tbl, 7 ex
SUBSTANCE: invention refers to medicine, more specifically to chemical-pharmaceutical industries and medical equipment. What is described is a fixer representing an adhesive tape consisting of paper base 45-55 g/m and a pressure sensitive adhesive coating one of the base sides. The adhesive layer is protected by siliconised paper.
EFFECT: agent provides higher adhesive properties, better vapour permeability, does not irritate skin, possess higher viability.
5 cl, 2 tbl
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medical equipment and may be used in producing adhesive elements for colo-, ileo- and urostomy bags and urine collection bags. The composition contains, wt %: acrylate copolymer 10-20, polyisobutylene 15-35, castor oil 10-20, hydrocolloids 20-30, and a target additive 0.1-30.
EFFECT: invention aims at preparing the adhesive polymeric composition having improved adhesion to polyolefines and natural latex, and also has a therapeutic and preventive action on skin, causes no irritations and erythemas.
4 cl, 1 tbl, 5 ex
SUBSTANCE: present invention refers to medicine, more specifically to a gel composition for a medical material or a hygienic material which contains a liquid rubber ingredient having a functional group able to create cross linkages, in a molecule, and 90 weight parts or more and 1250 weight parts or less of an organic liquid ingredient in relation to 100 weight parts of the rubber ingredient with the gel composition being cross-linked.
EFFECT: composition for the medical material or the hygienic material contains a great amount of the organic liquid ingredient, has sufficient elasticity and can hold its shape.
7 cl, 4 tbl
SUBSTANCE: invention refers to medicine. What is described is a bandage for pain region processing. The bandage provides cooling and delivery of therapeutic formulations to this region. The bandage comprises a bearing carrier, an interpenetrating network of gel-type dope of polyvinyl alcohol and a cross-linking agent wherein the interpenetrating network is located in the bearing carrier, and at least one additional therapeutic agent.
EFFECT: bandage may be applicable many times on various body parts.
21 cl, 4 dwg, 3 ex
SUBSTANCE: invention refers to medicine. There are described methods for preparing biomaterials to be used as a woven sealant, complete sets containing precursors for preparing the biomaterials, and the resultant biomaterials. The biomaterials are prepared of the composition containing at least molecules of the first and second precursors, wherein: i) a molecule of the first precursor is a polymer of poly(ethylene glycol) having x nucleophilic groups specified in a group consisting of thiol or amine groups, wherein x is equal to 2 or more, preferentially 3, 4, 5, 6, 7 or 8; ii) a molecule of the second precursor is described by general formula: A-[(C3H6O)n-(C2H4O)m-B]i, wherein m and n represent integers within the range 1 to 200, i is more than 2, preferentially 3, 4, 5, 6, 7 or 8, A represents a junction point, B represents a conjugated unsaturated group.
EFFECT: biomaterials are able to glue tissue surfaces together quickly without complication of common therapy.
1 tbl, 10 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine. What is described is a superabsorbent polymer composite containing superabsorbent polymers and cellulose nanofibrils having a diameter of 100 nm or less. The composite may be presented in the form of either particles, or foam. There are also described methods for preparing the composite and absorbent products containing the superabsorbent polymer composite.
EFFECT: cellulose nanofibrils improve the gel strength of the superabsorbent polymer.
23 cl, 6 dwg, 6 ex