Method of correcting microcirculatory disorders in case of chronic catarrhal gingivitis in people
SUBSTANCE: invention relates to field of medicine, namely to dentistry, physiotherapy. Method includes influence by defocused shock wave through applications of enterosorbent "BS-P", applied on upper and lower jaw. Influence by shock wave is realised through soft tissues of maxillofacial area. Influence is performed with pulse duration 0.4-0.7 mcs, pulse frequency 90 Hz, pressure amplitude from 6 to 9 MPa, total number of pulses 1000. Procedures are carried out every second day. Course includes 7-10 sessions.
EFFECT: method enhances reparative processes due to correction of disorders of microcirculation and metabolism stimulation.
The present invention relates to medicine, in particular to physical therapy, and can be used in dental clinics, medical institutions, departments of rehabilitation treatment and rehabilitation centers.
The prevalence of chronic diseases of the oral cavity necessitates the development of new methods of treatment and prevention of these diseases. Gingivitis, an inflammatory process of the mucous membrane and tissues of the gum disease, the most common as adolescents and adults. Chronic catarrhal gingivitis may develop in smokers, on the background of gastrointestinal diseases, diseases of the endocrine system. According to clinical observations, untreated or insufficiently treated gingivitis leads to severe destructive processes in periodontal tissues, which is the main cause of tooth loss (Borovsky E.V., Ivanov V.S., 2001, Straka M, 2000). According to some authors, an important pathogenetic mechanism of diseases of the tissues of the mouth are disorders in the microcirculation of blood (Kukharenko J.V., 2005; Crecine E.K., 2007).
Numerous studies have shown that abnormalities in the microcirculation of the blood can be caused by both structural and functional changes in the vessels: reduced the eating of the number of functioning capillaries, violation of their permeability, the change of the aggregation properties of blood (Kropotkin A.I. Sidorov V.V., Baranov V.V., 2007).
In the practice of physiotherapy known method of treatment and correction of microcirculation in chronic catarrhal gingivitis using electrophoresis of drugs - the combined action of the constant current low voltage (30-80) and low intensity (up to 50 mA) and drug substance incorporated with it in the tissue (ulasik B.C., "Popular physiotherapy, 2003). The disadvantage of this method is the presence of contraindications associated with common diseases, and allergic reaction to injected drugs.
The known correction method microcirculation in acute exacerbations of chronic catarrhal gingivitis using broadband electromagnetic therapy based on the use of electromagnetic fields in the frequency range from 10 kHz to 1 GHz (Beketov E.N., Broadband electromagnetic therapy as a modern non-pharmacological treatment and secondary prevention of catarrhal gingivitis, 2006). The disadvantage of this is similar contraindications apply when the related common diseases, as well as individual intolerance of the high frequency current.
The closest in technical essence to appreciate the suggested method is a method of correction of microcirculation in chronic catarrhal gingivitis by conducting vibration massage implying the influence of mechanical vibrations of low frequencies on the processes of microcirculation in the tissues. Vibration massage is carried out with the help of special devices (EMF-2, "Vibratory") with vibrators adapted for vibratory massage of the gums. The patient in the right hand give the vibratory apparatus, selects the desired frequency of vibration and the device included in the network. Set the head of the vibrator on transitional fold the vestibule of the mouth and move it in a vertical plane. Exposure start with 1-2 minutes, gradually increasing to 5 minutes on each jaw. In the course of treatment prescribed to 20 treatments daily or every other day. In the year can be 2 courses with an interval of 4-6 months. (Limcaoco, Ahinigopiv, Eaaea, Diagnosis, treatment and prevention of periodontal diseases, 2008). The disadvantage of this method is associated with painful procedures, caused by the necessity of direct contact of the nozzle apparatus with the inflamed area of the gums, which can lead to additional injury to the gums.
The technical result of the proposed method of correction of disorders of microcirculation in chronic catarrhal gingivitis in humans is to reduce painful and edematous syndromes, activation of microcirculation and neoangiogenesis, stimulation of metabolic processes, unilinearity processes, anti-inflammatory and antibacterial action.
This technical result is achieved by exposure to any reservation or shock wave generated by the electromagnetic system "CD", with a pulse duration of 0.3 to 0.6 μs, pulse frequency 90 Hz, with gradually increasing pressure amplitude from 5 to 9 MPa in the maxillofacial region through the soft tissue prior to application of the conductive gel and guidance of the head of the generator on the upper and lower jaw, are imposed on the application of enterosorbent "BS-" P adsorption capacity of 39.4 percent, a specific surface area of pores 2000 m2/g for 10-15 minutes, a total of 1000 pulses at the rate of 7-10 procedures.
The choice of the combination of the two factors on periodontal tissues, any reservation or shock wave generated by the electromagnetic system "CD", and applications of enterosorbent "BS-P, the proposed method of correction of disorders of microcirculation in chronic catarrhal gingivitis in man is justified by the fact that the properties of the enterosorbent "BS-P" to effectively absorb the chemical mediators of exudation and edema, to provide bacteriostatic and hemostatic effects potentiate the effects of any reservation or shock wave, which consists in improving microcirculatory reserve is in the gum tissue, stimulation of compensatory-adaptive mechanisms of the biochemical nature.
Description of the method
The patient is placed in the dental chair with head thrown back. On the surface of the gums impose application packages containing powder form enterosorbent "BS-P". In the maxillofacial region is applied conductive gel and impact shock wave on the upper and lower jaw through the soft tissue. For shock-wave effects is complex "Compact" with the electromagnetic system the generation of shock waves with structurally produced defocusing of shock waves. The patient affected by any reservation or a shock wave with a pulse duration of 0.4 to 0.7 μs, pulse frequency of 90 Hz. The amplitude of the pressure during the session gradually increases from 6 to 9 MPa, the total number of pulses 1000 pulses for 10-15 minutes. Procedures are performed through the day, the course includes 7-10 sessions.
Examples of the method.
Example 1. Patient K. was born in 1975 admitted with complaints on pain when eating, bleeding gums during brushing. Smokes more than 15 years. Chronic diseases have been identified. In a study of marked redness and slight swelling of the gums, the soft dental plaque.
To evaluate what microcirculation periodontal complex used laser analyzer of the speed of surface capillary blood flow "LACC-01" ("SPE " Lazma", Russia)equipped with a helium-neon laser (LGN-208). In evaluating the performance of basal blood flow periodontal complex revealed a low value of the average of the microcirculation 8 PFED, norm - 12 PFED underestimated the amount of nutritive blood flow (489 PFED/mm Hg, the norm - 790 PFED/mm Hg). To the patient in the dental chair, put appliques enterosorbent "BS-P" on the upper and lower jaw and causing the conductive gel on the maxillofacial region. Then hit any reservation or shock wave on the area of the lower and upper jaw. For shock-wave effects used complex "Compact" with the electromagnetic system the generation of shock waves with structurally produced defocusing of shock waves. The patient was affected by any reservation or a shock wave with a pulse duration of 0.4 to 0.7 μs, pulse frequency of 90 Hz. The amplitude of the pressure during the session gradually increased from 6 to 9 MPa, the total number of pulses was increased to 1000 pulses for 10-15 minutes. Procedures are performed through the day, the course consisted of 7 treatments. Portability procedures in all cases was good, the pain did not occur.
As a result of treatment the soreness when you are eating significantly decreased bleeding and OTE the gum was not observed. The value of the average of the microcirculation increased to 11 pfet, the amount of nutritive blood flow increased to 783 PFED/mm Hg, the parameters of microcirculation was close to normal.
Example 2. Patient F., born in 1963 was admitted with complaints on the discomfort in the gums, itching, bleeding gums while brushing teeth, pain while eating in the result of the influence of mechanical and chemical stimuli. The patient is monitored by a gastroenterologist in occasion of a chronic gastritis. On physical examination, marked swelling, redness of the gums, her thickening, mechanical irritation accompanied by bleeding.
The parameters of microcirculation periodontal complex, obtained using a laser analyzer of the speed of surface capillary blood flow "LACC-01", revealed a low value of the average of the microcirculation of 7.5 PFED, norm - 12 PFED underestimated the amount of nutritive blood flow 491 PFED/mm Hg, the norm - 790 PFED/mm Hg
The patient in the dental chair, put appliques enterosorbent "BS-P" on the upper and lower jaw and causing the conductive gel on the maxillofacial region. Then hit any reservation or shock wave on the area of the lower and upper jaw. For shock-wave effects used com is Lex "Compact" with the electromagnetic system the generation of shock waves with structurally produced defocusing of shock waves. The patient was affected by any reservation or a shock wave with a pulse duration of 0.4 to 0.7 μs, pulse frequency of 90 Hz. The amplitude of the pressure during the session gradually increased from 6 to 9 MPa, the total number of pulses was increased to 1000 pulses for 10-15 minutes. Procedures are performed through the day, the course consisted of 9 treatments. Portability procedures in all cases was good, the pain did not occur.
As a result of the course of treatment significantly reduced pain when eating, bleeding during mechanical stimulation is not observed, observed residual signs of redness and swelling of the gums. The value of the average of the microcirculation increased to 9 pfet, the amount of nutritive blood flow increased to 773 PFED/mm Hg, the figures came closer to normal
The proposed method of correction of microcirculation was tested on 46 patients aged from 27 to 54 years. Research was conducted on the basis of the fgbi "RRC MP and To the Ministry of health of Russia on the basis of dental polyclinic №35 of Moscow (Moscow). As a result of application of this method was observed to increase initially conservative values of the average of the microcirculation from 7.3 to 11 pfet, the increase in nutritive blood flow from 490 to 787 PFED/mm Hg In all cases there was a significant decrease shall prolong bleeding, redness, swelling gums. Clinical trials have shown high efficiency of the proposed method and had no complications.
The proposed method of correction of disorders of microcirculation in chronic catarrhal gingivitis in humans has a pronounced anti-inflammatory effect, enhances the regenerative processes of microcirculation, stimulates the flow of metabolic processes, which provides a significant increase in clinical efficacy and rapid regression of the main signs of the disease.
No side effects and good tolerability physiotherapeutic factors allow us to recommend this method for General use as a correction of microcirculatory disorders arising from inflammation of the periodontium, in particular in chronic catarrhal gingivitis.
The correction method of the microcirculation in chronic catarrhal gingivitis in humans by exposure to physical factors, characterized in that the patient carry out the simultaneous impact of applications of enterosorbent "BS-" P adsorption capacity of 39.4 percent, a specific surface area of pores 2000 m2/g imposed on the upper and lower jaws, and any reservation or shock wave on the upper and lower jaw through the soft tissues of the maxillofacial area with glutelin the STU pulse of 0.4-0.7 µs, the pulse frequency of 90 Hz, the amplitude of pressure from 6 to 9 MPa, the total number of pulses 1000 and within 10-15 minutes, the procedures are performed through day treatment 7-10 treatments.
SUBSTANCE: group of inventions refers to medicine, and aims at treating patient's oral diseases. Cultured tissue constructs of fibroblast dermal cells are implanted onto the oral tissue. The cultured tissue constructs comprise the cultured cells and endogenous-produced extracellular matrix components without the exogenous matrix or network sustaining or scaffold links.
EFFECT: group of inventions enables providing more simple and less painful treatment of the oral diseases requiring the implanted tissue constructs to be used.
33 cl, 36 ex, 21 dwg
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine and relates to disturbed salivation. A composition containing sialic acid for treating or preventing the diseases related to disturbed salivation contains a protein fraction containing 7 to 25 wt % of N-acetylneuraminic acid and threonine in the amount of 8 to 22% of total amino acids, wherein N-acetylneuraminic acid is bound to a threonine-enriched peptide-protein network.
EFFECT: invention enables increasing salivation, especially observed in elderly persons and accompanying such diseases as dysphagia, xerostomia and a combination thereof.
23 cl, 2 dwg
SUBSTANCE: group of inventions relates to dental seals and methods of their application. Composition of dental seal in form of varnish includes arginine in free form or in form of salt, rosin, white beeswax, mastic, shellac and source of fluoride ions, which is present in composition in concentration, at least 12 wt %, and is selected from group, including tin fluoride, sodium monofluorophosphate, sodium fluorosilicate, ammonium fluorosilicate, amine fluoride, aluminium fluoride, sodium hydrofluoride, sodium fluoride, calcium fluoride, magnesium fluoride and potassium fluoride. Also claimed is method of treating sensitive teeth, which includes application of said seal composition in form of varnish on tooth of person, requiring treatment, and application of claimed method for improvement of oral cavity health. Application of arginine in said composition of dental seal makes it possible to use fluoride-ions in a larger quantity than is usually used in dental varnishes, without side effects, associated with excess of fluoride-ions.
EFFECT: composition of seal makes it possible to ensure regulated continuous supply of medication.
12 cl, 2 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine, particularly to pharmacy and dentistry, and concerns creating new compositions of menthol derivatives. For this purpose, 2-isopropyl-5-methylcyclohexyl-2-hydroxyphenylcarbamate is suggested to be used as an antioxidant, anti-inflammatory and antimicrobial agent for local treatment of the oral cavity, e.g. periodontal diseases. That provides the basis to present the compositions containing an effective amount of 2-isopropyl-5-methylcyclohexyl-2-hydroxyphenylcarbamate, and at least one excipient.
EFFECT: inventions provide treating the oral cavity ensured by an integrated effect on general mechanisms of pathogenesis.
7 cl, 7 tbl, 2 ex, 5 dwg
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutics and represents a method of preventing and treating oral inflammation following a dental surgery, comprising in applying a drug preparation on an incisional wound daily in a patient underwent the implantation procedure and characterised by the fact that the drug preparation used represents a preparation of the strain lactobacillus plantarum 8P-AZ and/or B.bifidum in a dose of at least 10 million live lactic acid bacilli and/or bifidus bacteria.
EFFECT: invention provides simplifying the method of preventing and treating the oral inflammation by making it unnecessary to prepare the drug used if antibiotics are avoided.
2 cl, 9 ex, 9 dwg
FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to chemical-pharmaceutical and cosmetic industry and represents artificial saliva containing arginine either in the free form, or in the form of a salt together with one or more of: a) a calcium ion source, b) a phosphate ion source, c) a potassium ion source, d) a magnesium ion source, e) a fluoride ion source; f) a flavour stimulating saliva flow; and/or g) a polyol humidifier.
EFFECT: invention provides creating the agent containing arginine or a salt thereof for treating, improving, slowing or preventing dry mouth.
8 cl, 3 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutics and represents an agent for local treatment of periodontal diseases, on the basis of organosilicone gycerohydrogel Si(C3H7O3)4·6C3H8O3·24H2O, containing therapeutic supplements, differing by the fact that the therapeutic supplements are presented by ketoprofen and methyluracil in the following proportions, wt %: ketoprofen - 0.5 - 1.0; methyluracil - 1.0 - 1.5; organosilicone gycerohydrogel Si(C3H7O3)4·6C3H8O3·24H2O - up to 100.
EFFECT: invention provides creating the effective agent applicable in the integrated therapy for treating the inflammatory periodontal diseases.
SUBSTANCE: invention relates to medicine, namely to dentistry. Method includes processing perforated root canal and perforation zone with laser irradiation and covering perforation with sealing material. Introduction of light-guide into perforated root canal is carried out. In processing by laser irradiation translational increase of its power parameters is used. During the first session processing is carried out with power 0.5 W, during the second session - 0.75 W, during the third - 1.5 W. Additionally ozone therapy with saturated physiological solution is performed. Time of saturation with ozone is 5 minutes. Concentration of ozone dissolved in physiological solution is 8.8-9.6 mg/l.
EFFECT: method is painless, does not require carrying out local anesthesia, excludes allergic reactions, ensures optimal bactericidal and bacteriostatic effect, which makes it possible to efficiently stop inflammation and reconstruction of bone tissue, reduces number of complications.
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine, namely to dentistry, and concerns preparations for preventing and treating the diseases of periodontal membrane and oral mucosa. That is ensured by using a pharmaceutical composition in the form of a gel which contains metronidazole benzoate, chlorhexidine gluconate as an active substance and additionally the ingredients specified in a group of alpha-, beta-, gamma-, recombinant interferon.
EFFECT: invention provides reducing the length of treatment in the patients with inflammatory periodontal diseases due to the wide spectrum of action of the composition, prolonged fixation on gums, which accelerates the regeneration of the oral mucosa.
2 cl, 5 ex
SUBSTANCE: invention refers to medicine, namely dentistry, and may be used for local therapy of inflammatory periodontal diseases. That is ensured by the daily applications of powdered cellulose surgical cotton on a dentogingival edge after curettage to normalise the microcirculation and hemodynamic values.
EFFECT: method provides higher clinical effectiveness in periodontal diseases, reduced complications and disability periods due to normalising the free radical levels in the damaged tissue while reducing inflammation and accelerating the process of epithelialisation of periodontal tissues.
SUBSTANCE: invention relates to surgery and can be applied for prevention of recurrence in low anterosuperior apparatus resection. After formation of low stump of rectum by suturing apparatus before formation of apparatus anastomosis with preventive ileostomy, physiological saline is introduced into stump through anus and extracted with measurement of its volume. Chemical preparation is diluted, with application of solvent volume, equal to volume of rectum stump lumen minus volume of introduced ultrasonic instrument. Solution of chemical preparation is introduced into rectum stump. Ultrasonic instrument is placed into rectum stump through anus. Ultrasonic vibrations with mode 880 Hz, 0.2 W/m2 are excited in solution for 7 minutes. After that, low apparatus anastomosis is formed.
EFFECT: method makes it possible to reduce risk of recurrence.
SUBSTANCE: relates to medicine and can be applied for prevention of metastatic disease in case of right-side hemicolectomy. After laparotomy, 30 ml of solution,which contains chemical preparation, are introduced into mesentery with formation of infiltrate along mesostenium vessels in direction of orifice of upper mesenteric artery. Infiltrate is exposed to ultrasonic instrument with mode 880 Hz, 0.7 W/m2 for 15 minutes, with obtaining maximal concentration of preparation in walls of vessels, lymph nodes and tissues of mesentery.
EFFECT: method makes it possible to reduce risk of metastatic disease.
SUBSTANCE: invention relates to medical equipment. An ultrasonic probe comprises a body with a connector, and a syringe. The spring comprises a working portion of the probe coupled with the connector. The connector is provided with a cap. An internal diameter of the cap matches with an external diameter of the connector. A cap point is conical. The cap is plastic; it has long slots and a lock ring. The spring is coupled with the cap point. The working portion of the probe is bend and coupled with the connected. The cap slot length makes 0.4-0.45 of its length, while the spring length makes 0.55-0.60 of the cap length.
EFFECT: using the invention enables improving the clinical effectiveness with the improved use reliability of the probe ensured by providing greater flexibility of the working part and connector coupling.
SUBSTANCE: invention refers to medical equipment, namely to apparatuses for thermal and photochrome ultrasound treatment of osteoarthrosis of various nosologies. The apparatus comprises a control unit, a low-frequency ultrasonic vibration source in the form of an acoustic system accommodating a disc emitter connected to a piezoelectric transducer; there are also provided a knee pad impregnated with an ozone/NO-containing agent, a light-emitting array with distributed red, green and blue solid-state light-emitting diodes. The solid-state light-emitting diodes are seated into the spring light-emitting array coupled with an insulating guard spring plate secured on a carrying pad coupled form the inside with a damping element contacting with the knee pad. The solid-state light-emitting diodes are yellow, infer-red and ultraviolet and seated in the holes formed in the carrying pad and damping element. Each acoustic system is fixed on the carrying pad and configured so that it operates at a resonance frequency within the range of frequencies of 22 kHz to 100 kHz. The piezoelectric transducer contacts with a disc spring hollow guide filled with an immersion medium contacting with the knee pad. The carrying pad is connected from the outside with a carrying holder coupled with a control unit body comprising a display; further, it is provided with two elastic fastening belts on each side.
EFFECT: using the invention enables the higher clinical effectiveness in osteoarthrosis ensured by providing the effect of the complex of physical and physical-chemical factors on the joint.
1 cl, 10 dwg
SUBSTANCE: invention relates to medicine, namely to rheumatology and physiotherapy, and can be used for treatment of osteoarthrosis. For this purpose general iodine-bromine baths are carried out. Additionally from the second day of treatment on days, free of general iodine-bromine baths, ultraphonophoresis of gel "Bishofit" is performed. For this purpose area of flexion surface of knee, elbow, radiocarpal, field of anterior surface with transition on the rear of foot of ankle joint, field of external surface with transition on anterior and posterior surface of shoulder joint are preliminarily processed with 30% dimexide solution and after 15 minutes with thin, 1-2 mm thick, layer of gel "Bishofit". After that, zones of affected joints are influenced by irradiating head of apparatus "UZT-1.01 F", with area 4 cm2 in contact, labial manner, in continuous mode, with irradiation intensity from 0.4-0.6 to 1.0 W/cm2, time of exposure constitutes 10 minutes. Course of treatment includes 8 physio- and 8 balneo- procedures.
EFFECT: method ensures increase of efficiency and reduction of terms of treatment due to expressed anti-inflammatory, pain-killing effect, positive general and local trophic influence, improvement of state of vegetative nervous system, as well as elimination of balneopathological reaction.
6 tbl, 1 ex
SUBSTANCE: invention relates to medicine, namely to maxillofacial surgery, plastic, reconstructive surgery, otolaryngology. Selective destruction of water-saturated components of tumour tissue of rhinophyma is carried out by waveguide with fluctuation frequency 25 kHz and fluctuation amplitude from 100 to 120 mcm. Fibrous adhesions of rhinophyma are excised at frequency of fluctuations 35-55 kHz and amplitude of fluctuations from 100 to 120 mcm to healthy tissues layer-by-layer. Coagulation of superficial components of rhinophyma is performed by argon plasma coagulator with flow rate 1-3 l/min to the moment of scab formation.
EFFECT: method makes it possible to increase treatment efficiency due to minimal thermal injury to tissues and reduction of blood loss, which makes it possible to avoid coarse scab deformations of soft tissues and internal structures of nose.
SUBSTANCE: invention refers to medicine, specifically to surgery. The heart ultrasound is involved. A set of heart compression attributes is scored. If observing a pyriform change of the right ventricle geometry, 2 points is scored; and a dumbbell change of the right ventricle geometry stands for 2 points. That is followed by describing an M-mode systolic excursion of an interventricular septum being 3 mm - 1 point is scored, 2 mm - 2 point, and 1 mm - 3 points. Asynchronous contractions of the interventricular septum shows 3 points. Then, 1 point is scored if observing a speed increase of the transtricuspid flow. A decrease of the M-mode end diastolic size of the right ventricle makes scoring 1 point. Further, 1 point is added if observing the changes of the right atrium changes. Total score is calculated: the value of 10 points and more is an invariable indication for a surgical intervention; the total score of 4-5 requires the Nuss surgical intervention; 2-3 points mean a relative indication for the surgical intervention; and 1 point means no indications for the surgical intervention.
EFFECT: method enables the objective assessment of the heart compression to ensure the adequate planning of the surgical intervention.
1 tbl, 5 dwg
SUBSTANCE: invention refers to medicine, namely to oncology, and can be used for treating patients with tongue cancer. For this purpose, on the 1st therapeutic day, taxotere 100 mg/m2 and cisplatin 50 mg/m2 are introduced intravenously drop-by-drop. One week later, a primary site and regional metastases are exposed distant gamma-therapy by accelerated fractionation in a single basic dose of 2.4 Gy fractionated by 1.2 Gy every 5 hours to a total basic dose of 40 isoGy. Every second day, in the middle of the 5-hour interval of the separate radiation fractions, platidiam 5 mg dissolved in actovegin gel is administered to the primary site, while the tumour is exposed to ultrasound at frequency 880 kHz and intensity 0.4 Wt/cm2 for 5 minutes. The therapeutic course is 9 administrations. After the 2-week interval of the radiation therapy, the chemotherapy is repeated as specified in the above regimen. The distant gamma-therapy in a single basic dose of 2.4 Gy, 1.2 Gy every 5 hours is conducted to a total basic dose of 60±4 isoGy. Between the radiation fractions, platidiam 5 mg dissolved in actovegin gel is administered to the primary site, while the tumour is exposed to ultrasound at frequency 880 kHz and intensity 0.4 Wt/cm2 for 5 minutes. The therapeutic course is 5 administrations.
EFFECT: method provides improving the therapeutic effect and quality of life in the patients with regional tongue cancer, including through a combination of the systemic and local administration of cytotoxic drugs, the effect of sonosensitisation and deeper penetration of the chemotherapeutic preparation into the full-thickness tumour as ensured by the intensive effect of ultrasound with underlying radiation therapy.
SUBSTANCE: invention refers to medicine, namely to neurology, neurosurgery and rehabilitation, and may be used to recover the sensor-motor function of the central nervous system and peripheral nerves. The therapy is three-staged. At the first stage, at least two hollow electrodes made of biologically neutral conductive material in a proximal and distal direction from a nerve injury are implanted into the nerve. The second stage involves at least one course of a focused extracorporeal shock-wave therapy consisting in at least five sessions in a combination with intraneural electric stimulation and intraneural ionic medication aiming at stimulating the growth of peripheral nerve fibre axons and the regeneration of Schwann cells forming the medullary sheath. At the third stage, the implanted electrodes are removed, and at least one session of transcutaneous electric stimulation with one-step electric myoneurography is conducted to coordinate neural pulses passage through the newly formed peripheral nerve synapses.
EFFECT: method provides the high therapeutic effectiveness in case of injuring up to 90% of neural synapses, reduced length of rehabilitation up to the complete recovery in the patient with no contra-indications and a possibility of the outpatient care.
SUBSTANCE: invention refers to medicine, namely dentistry, and may be used for treating herpetic stomatitis in HIV-patients. That is ensured by conducting a therapy that involves anti-herpetic, analgesic and anti-inflammatory preparations. From the very beginning of the therapy, the 2-week oral administration of glyciram 0.05-0.01 g is prescribed 2-4 times a day after a meal. In addition, the oral mucosa is topically exposed to low-frequency ultrasound oscillations with amplitude of oscillation 30-35 mcm, with frequency of cavitation 24.5-28.5 kHz for the first minute through an aqueous solution of glyciram. The aqueous solution of glyciram is prepared in advance at 0.025 mg of glycyram granules per 100 ml of warm boiled water. The therapeutic course is 10-14 ultrasonic procedures.
EFFECT: method provides the increased clinical effectiveness ensured by eliminating the side effects and reducing the severity of the disease.
SUBSTANCE: invention refers to medicine, specifically to physiotherapy, surgery. A method consists in conducting a course of pelotherapy by applications. The therapy is started within the first four weeks following a laparotomy. The therapy involves the sulphide mud applications on an anteriolateral abdominal wall. The sulphide mud temperature is 42° C. The application length is gradually increased from 10 to 20 minutes. The procedures are performed every second day. A minimum number of the applications is 10.
EFFECT: method reduces the peritoneal adhesions.