Insecticidal combination of active substances, use thereof and seed material


FIELD: chemistry.

SUBSTANCE: invention relates to agriculture. The combination of active substances contains at least one known compound of formula and at least another active substance from macrolides and carboxylates. The combination is used to treat seed materials or seed materials of transgenic plants, or transgenic plants.

EFFECT: invention reduces the amount of insecticides and widens the range of controlled pests.

6 cl

 

The present invention relates to control of noxious animals, and more particularly to insecticidal combinations of active substances, its application and seed material.

It is known that the compounds of formula (I):

,

in which

And means of pyrid-2-yl, pyrid-4-yl, pyrid-3-yl, optionally substituted in position 6 by fluorine, chlorine, bromine, stands, trifluoromethyl or triptoreline, pyridazin-3-yl, optionally substituted in the 6 position by chlorine or stands, pyrazin-3-yl, 2-chloropyrazine-5-yl or 1,3-thiazol-6-yl, optionally substituted in position 2 by chlorine or stands, or

And means pyrimidinyl, pyrazolyl, thiophenyl, oxazolyl, isoxazolyl, 1,2,4-oxadiazolyl, isothiazole, 1,2,4-triazolyl or 1,2,5-thiadiazolyl, which is optionally substituted by fluorine, chlorine, bromine, cyano, nitro, alkyl with 1-4 carbon atoms, optionally substituted by fluorine and/or chlorine, alkylthio with 1-3 carbon atoms, optionally substituted by fluorine and/or chlorine, or alkylsulfonyl with 1-3 carbon atoms, optionally substituted by fluorine and/or chlorine, or

A represents the residue of the formula:

,

in which

X means halogen, alkyl or halogenated, and

Y represents halogen, alkyl, halogenated, halogenoalkane, azido or cyano,

and

R1means and the keel, halogenated, alkenyl, halogenoalkanes, quinil, cycloalkyl, cycloalkenyl, halogenosilanes, alkoxy, alkoxyalkyl or halogennitroalkanes,

possess insecticidal properties and can therefore be used for control of noxious animals (see European patent application EP 0539588 and international application WO 2007/115644, WO 2007/115643 and WO 2007/115646). In addition, their use for the treatment of seed material is known from the application WO 2006/037475.

In addition, it is known that certain active substances from the class of macrolides, carboxylates or other classes possess insecticidal and acaricidal properties. Connections of the specified type are described in the relevant patent and technical literature. Most are listed in the present application insecticidal compounds from the class of macrolides, carboxylates or other classes are commercially available individual active substances used in the means for control of noxious animals. Such compounds and containing means described in the guide to pesticides "The Pesticide Manual", 14th edition, .D.S. Thomlin (publisher), British Crop Protection Council, Surrey, UK, 2006, which is when considering much of the following active substances from the class of macrolides, carboxylates or other classes should be considered an appropriate reference. Operating the substances, not with the commercial availability and are not cited in the above-cited guidance, identify in accordance with IUPAC number and/or structural formula.

Insecticidal compounds of formula (I), respectively, of the active substances from the class of macrolides, carboxylates or other classes in General have high efficiency. However, at low norms of expenses and in case of use to control certain pests, these connections do not fully meet the requirements of practice, and therefore there is a need for new cost-effective and environmentally safe means of protection of plants from pests.

Other requirements for insecticidal compounds requirements are lower dosages; a significant expansion of the range subject to pest control, which must also include persistent pests; increase the safety of use; reduction of toxicity towards plants, and, consequently, improve compatibility with plants; can be used for protection against pests at different stages of development; optimization of the technological properties, for example, the behavior during the shredding or mixing and during storage or use; favorable biosign the e action including low concentrations, and therefore, good tolerance of warm-blooded animals, fish and plants, as well as the possibility of providing additional effects, such as effects, characteristic of algaecides, anthelminticum, avicides, bactericides, fungicides, molluscicides, nematicides, means for activating the plants, rodenticides or virucidal.

Other specific requirements insecticidal compounds used in relation to the materials for vegetative and generative propagation of plants, are negligibly small phytotoxicity in the processing of seed materials and materials for propagation, compatibility with the soil (for example, the absence of binding soil), systemic action in plants, no adverse impact on the viability and effectiveness throughout the life cycle of the relevant pest.

The present invention was based on the task, which is to satisfy one or more of the above requirements insecticidal compounds, for example, to reduce the dosing amount and to expand the list of being the extermination of pests, including resistant species, and primarily we are talking about the need to meet the specific requirements applicable to the tee insecticidal compounds to materials for vegetative and generative propagation of plants.

The problem is solved, we offer insecticidal combination of active substances containing at least one compound of formula (I):

,

in which

And means 6-chloropyrid-3-yl and R1mean 2-foradil or 2,2-dottorati, or a represents 5-fluoro-6-chloropyrid-3-yl and R1means methyl,

and at least one compound selected from the group consisting of:

(1) spinosad,

(2) abamectin,

(3) emamectin-benzoate,

(4) milbemectin,

(5) indoxacarb,

(6) fipronil,

(7) ethiprole,

(8) chlorfenapyr,

(9) diafenthiuron,

(10) tebufenpyrad,

(11) fenpyroximate,

(12) canoperate,

(13) titlemotion,

(14) amitraz,

(15) cyromazine,

(16) pyridaben,

(17) flonicamid,

(18) pymetrozine,

(19) periglaciation,

(20) rynaxypyr,

(21) Casimir,

(22) metaflumizone and

(23) O-{(E)-2-(4-chlorophenyl)-2-cyano-1-[2-(trifluoromethyl)phenyl]ethynyl}-8-methylthiocarbamate.

Further objects of the invention are the use of combinations of active ingredients for control of noxious animals and for the treatment of seed material or transgenic plant or seed material of transgenic plants, seeds, processed combination of active substances. When this seed material may be subjected to the simultaneous processing of the active substance of the formula (I) and one of the active substances from the specified group or processed active substance of the formula (I) and one of the active substances from this group, executed at different points in time.

Spinosad having the formula

,

known from European patent application EP-A 0375316. It preferably is a mixture of 85% spinosyn A (R is hydrogen) with 15% of spinosyn (R is methyl).

The abamectin, having the formula

,

known from German application DE-A 2717040. It preferably is a mixture of >80% embryo death B1a(R is ethyl) and <20% of embryo death B1b(R is methyl).

Emamectin-benzoate having the formula

,

known from European patent application EP-A 0089202. It preferably is a mixture of >90% emamectin B1a(R is ethyl) and <10% emamectin B1b(R is methyl).

Milbemectin having the formula

known from Japanese patent JP 50029742. It preferably is a mixture of milbemycin And3

(R is methyl) and emamectin A4(R is ethyl) in the ratio 3:7.

Indoxacarb having the formula

,

known from international application WO 92/11249.

Fipronil having the formula

,

known from European patent application EP-A 0295117.

Amiprol having the formula

,

known from the German bid, medium, small the patent DE-A 19653417.

Chlorfenapyr having the formula

,

known from European patent application EP-A 347488.

Diafenthiuron having the formula

,

known from European patent application EP-A 210487.

Tebufenpyrad having the formula

,

known from European patent application EP-A 289879.

Fenpyroximate having the formula

known from European patent application EP-A 234045.

Canoperate (name of proposed ISO, NC-512), (1E)-2-cyano-2-[4-(1,1-dimethylethyl)phenyl]-1-(1,3,4-trimethyl-1H-pyrazole-5-yl)ethynyl 2,2-dimethylpropanoate formula (

,

known from Japanese patent JP 2003201280.

Titlemotion (name of proposed ISO, OK-5101) 2-methoxyethyl-alpha-cyano-alpha-[4-(1,1,dimethylethyl)phenyl]-beta-oxo-2-(trifluoromethyl)benzoylpropionate formula

,

known from international application WO 2002014263.

Amitraz having the formula

,

known from German patent application DE-A 02061132.

Cyromazine having the formula

known from German patent application DE-A 02736876.

Pyridaben having the formula

known from European patent application EP-A-134439.

and/or Flonicamid, is within the formula

,

known from European patent application EP-A 0580374.

Pymetrozine having the formula

,

known from European patent application EP-A 0314615.

Periplocoideae (name of proposed ISO, NNI-0101), 1-acetyl-1,2,3,4-tetrahydro-3-[(3-pyridylmethyl)amino]-6-[1,2,2,2-Tetra-fluoro-1 -(trifluoromethyl)ethyl]quinazolin-2-he, having the formula

,

known from European patent application EP-A 01097932.

Rynaxypyr (name of proposed ISO; chlorantraniliprole, DPX-E2Y45), (3-bromo-N-{4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl}-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide), having the formula

,

known from international application WO 03/015519.

Casimir name (proposed ISO), (3-bromo-N-{4-cyan-2-methyl-6-[(methylamino)carbonyl]phenyl}-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide), having the formula

,

known from international application WO 2004067528.

Metaflumizone (name of proposed ISO, BAS 320), 2-[2-(4-cyano-phenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifter-methoxy)phenyl]hydrazinecarboxamide having the formula

,

known from European patent application EP-A 00462456.

O-{(E)-2-(4-chlorophenyl)-2-cyano-1-[2-(trifluoromethyl)phenyl]ethynyl}-3-methylthiocarbamate having the formula

,

known from international application WO 98/35935.

Energeticheskie action proposed in the invention combinations of active substances containing a compound of the formula (I) and the active ingredient of the above group, it is possible to expand the range of highly active insecticides.

In addition to the above synergistic actions proposed in the invention combination of active ingredients able to provide other unexpected benefits, including improved safety, reduced phytotoxicity, and, therefore, higher tolerance of plants, the possibility of destruction pests at different stages of development, improvement of technological properties, for example, optimizing behavior during the shredding or mixing during storage or use insecticidal compounds, favorable biocidal action, including low concentrations, and, therefore, a high tolerance of warm-blooded animals, fish and plants, as well as the possibility of providing additional effects, such as effects inherent the algaecides, anthelminticum, avicides, bactericides, fungicides, molluscicides, nematicides, means for activating the plants, rodenticides or virucidal.

Especially high synergistic effect have proposed is, in the invention combination, active substances which are in a weight ratio to each other. However, this does not exclude the possibility of varying the mass ratio of active ingredients in the respective combinations in a fairly wide range. Proposed in the invention combination, containing the active substance of the formula (I) and one of the active ingredients of the above groups are generally characterized by the following mass ratios of components:

the preferred interval of mass ratios from 125:1 to 1:125,

particularly preferred interval of mass ratios from 25:1 to 1:25.

Under the mass ratio of the components involve the mass ratio of the compounds of formula (I) to the weight of one of the active ingredients of the above groups. Below is a list of possible intervals of the ratios between the compound of formula (I) and one of the active ingredients of the above groups in ascending order of preference: from 95:1 to 1:95, 95:1 to 1:90, from 95:1 to 1:85, 95:1 to 1:80, from 95:1 to 1:75, from 95:1 to 1:70, from 95:1 to 1:65, from 95:1 to 1:60 to 95:1 to 1:55, from 95:1 to 1:50, from 95:1 to 1:45, 95:1 to 1:40, from 95:1 to 1:35, from 95:1 to 1:30, 95:1 to 1:25, 95:1 to 1:20, 95:1 to 1:15, 95:1 to 1:10, 95:1 to 1:5, 95:1 to 1:4, 95:1 to 1:3, 95:1 to 1:2, 90:1 to 1:90, from 90:1 to 1:95, from 90:1 to 1:85, 90:1 to 1:80, from 90:1 to 1:75, from 90:1 to 1:70, from 90:1 to 1:65, from 90:1 to 1:60, from 90:1 to :55, from 90:1 to 1:50, 90:1 to 1:45, from 90:1 to 1:40, 90:1 to 1:35, from 90:1 to 1:30, 90:1 to 1:25, 90:1 to 1:20, 90:1 to 1:15, 90:1 to 1:10, 90:1 to 1:5, 90:1 to 1:4, from 90:1 to 1:3, 90:1 to 1:2, 85:1 to 1:85, 85:1 to 1:95, from 85:1 to 1:90, 85:1 to 1:80, 85:1 to 1:75, from 85:1 to 1:70, 85:1 to 1:65, from 85:1 to 1:60, from 85:1 to 1:55, 85:1 to 1:50, from 85:1 to 1:45, from 85:1 to 1:40, from 85:1 to 1:35, from 85:1 to 1:30, 85:1 to 1:25, 85:1 to 1:20, 85:1 to 1:15, 85:1 to 1:10, 85:1 to 1:5, 85:1 to 1:4, 85:1 to 1:3, 85:1 to 1:2, 80:1 to 1:80, from 80:1 to 1:95, from 80:1 to 1:90, from 80:1 to 1:85, from 80:1 to 1:75, from 80:1 to 1:70, from 80:1 to 1:65, from 80:1 to 1:60, from 80:1 to 1:55, 80:1 to 1:50, 80:1 to 1:45, from 80:1 to 1:40, 80:1 to 1:35, from 80:1 to 1:30, 80:1 to 1:25, 80:1 to 1:20, 80:1 to 1:15, 80:1 to 1:10, 80:1 to 1:5, 80:1 to 1:4, 80:1 to 1:3, 80:1 to 1:2, 75:1 to 1:75, from 75:1 to 1:95, from 75:1 to 1:90, from 75:1 to 1:85, from 75:1 to 1:80, 75:1 to 1:70, 75:1 to 1:65, 75:1 to 1:60, from 75:1 to 1:55 from 75:1 to 1:50, 75:1 to 1:45, from 75:1 to 1:40, 75:1 to 1:35, 75:1 to 1:30, 75:1 to 1:25, 75:1 to 1:20, 75:1 to 1:15, 75:1 to 1:10, 75:1 to 1:5, 75:1 to 1:4, 75:1 to 1:3, from 75:1 to 1:2, 70:1 to 1:70, 70:1 to 1:95, from 70:1 to 1:90, from 70:1 to 1:85, from 70:1 to 1:80, from 70:1 to 1:75, from 70:1 to 1:65, 70:1 to 1:60, from 70:1 to 1:55 from 70:1 to 1:50 from 70:1 to 1:45, from 70:1 to 1:40, 70:1 to 1:35, 70:1 to 1:30, 70:1 to 1:25, 70:1 to 1:20, 70:1 to 1:15, 70:1 to 1:10, 70:1 to 1:5, 70:1 to 1:4, 70:1 to 1:3, from 70:1 to 1:2, 65:1 to 1:65, 65:1 to 1:95, 65:1 to 1:90, 65:1 to 1:85, 65:1 to 1:80, 65:1 to 1:75, 65:1 to 1:70, 65:1 to 1:60, 65:1 to 1:55 from 65:1 to 1:50, from 65:1 to 1:45, 65:1 to 1:40, 65:1 to 1:35, 65:1 to 1:30, from 5:1 to 1:25, 65:1 to 1:20, 65:1 to 1:15, 65:1 to 1:10, 65:1 to 1:5, 65:1 to 1:4, 65:1 to 1:3, 65:1 to 1:2, 60:1 to 1:60, from 60:1 to 1:95, from 60:1 to 1:90, from 60:1 to 1:85, from 60:1 to 1:80, from 60:1 to 1:75, from 60:1 to 1:70, 60:1 to 1:65, from 60:1 to 1:55 from 60:1 to 1:50, 60:1 to 1:45, from 60:1 to 1:40, from 60:1 to 1:35, 60:1 to 1:30, 60:1 to 1:25, 60:1 to 1:20, 60:1 to 1:15, 60:1 to 1:10, 60:1 to 1:5, 60:1 to 1:4, 60:1 to 1:3, 60:1 to 1:2, 55:1 to 1:55 from 55:1 to 1:95, from 55:1 to 1:90, from 55:1 to 1:85, 55:1 to 1:80, from 55:1 to 1:75, from 55:1 to 1:70, from 55:1 to 1:65, from 55:1 to 1:60, from 55:1 to 1:50, 55:1 to 1:45, from 55:1 to 1:40, from 55:1 to 1:35, from 55:1 to 1:30, from 55:1 to 1:25, 55:1 to 1:20, 55:1 to 1:15, 55:1 to 1:10, 55:1 to 1:5, 55:1 to 1:4, 55:1 to 1:3, 55:1 to 1:2, from 50:1 to 1:95, from 50:1 to 1:90, 50:1 to 1:85, from 50:1 to 1:80, 50:1 to 1:75,50:1 to 1:70,50:1 to 1:65,from 50:1 to 1:60, 50:1 to 1:55 from 50:1 to 1:45, from 50:1 to 1:40, 50:1 to 1:35, from 50:1 to 1:30, from 50:1 to 1:25, from 50:1 to 1:20, from 50:1 to 1:15, from 50:1 to 1:10, from 50:1 to 1:5, 50:1 to 1:4, 50:1 to 1:3, from 50:1 to 1:2, 45:1 to 1:45, from 45:1 to 1:95, from 45:1 to 1:90, from 45:1 to 1:85, from 45:1 to 1:80, from 45:1 to 1:75, from 45:1 to 1:70, from 45:1 to 1:65, 45:1 to 1:60, 45:1 to 1:55 from 45:1 to 1:50, 45:1 to 1:40, 45:1 to 1:35, from 45:1 to 1:30, from 45:1 to 1:25, 45:1 to 1:20, 45:1 to 1:15 from 45:1 to 1:10, 45:1 to 1:5, 45:1 to 1:4, 45:1 to 1:3, 45:1 to 1:2, 40:1 to 1:40, from 40:1 to 1:95, from 40:1 to 1:90, from 40:1 to 1:85, from 40:1 to 1:80, 40:1 to 1:75, from 40:1 to 1:70, 40:1 to 1:65, about 40:1 to 1:60, from 40:1 to 1:55 from 40:1 to 1:50, from 40:1 to 1:45, from 40:1 to 1:35, from 40:1 to 1:30 PM, from 40:1 to 1:25, 40:1 to 1:20, from 40:1 to 1:15, from 40:1 to 1:10, from 40:1 to 1:5, 40:1 to 1:4, 40:1 to 1:3, 40:1 is about 1:2, from 35:1 to 1:35, from 35:1 to 1:95, from 35:1 to 1:90, from 35:1 to 1:85, from 35:1 to 1:80, 35:1 to 1:75, 35:1 to 1:70, 35:1 to 1:65, from 35:1 to 1:60, 35:1 to 1:55 from 35:1 to 1:50, from 35:1 to 1:45, from 35:1 to 1:40, from 35:1 to 1:30, 35:1 to 1:25, 35:1 to 1:20, 35:1 to 1:15, 35:1 to 1:10, 35:1 to 1:5, 35:1 to 1:4, 35:1 to 1:3, 35:1 to 1:2, 30:1 to 1:30, from 30:1 to 1:95, from 30:1 to 1:90, 30:1 to 1:85, from 30:1 to 1:80, 30:1 to 1:75, 30:1 to 1:70, from 30:1 to 1:65, 30:1 to 1:60, from 30:1 to 1:55, from 30:1 to 1:50, 30:1 to 1:45, from 30:1 to 1:40, from 30:1 to 1:35, from 30:1 to 1:25, from 30:1 to 1:20, from 30:1 to 1:15, from 30:1 to 1:10, from 30:1 to 1:5, from 30:1 to 1:4, from 30:1 to 1:3, from 30:1 to 1:2, 25:1 to 1:25, from 25:1 to 1:95, from 25:1 to 1:90, 25:1 to 1:85, 25:1 to 1:80, 25:1 to 1:75, from 25:1 to 1:70, 25:1 to 1:65, from 25:1 to 1:60, from 25:1 to 1:55, from 25:1 to 1:50 25:1 to 1:45, from 25:1 to 1:40, from 25:1 to 1:35, from 25:1 to 1:30, from 25:1 to 1:20, from 25:1 to 1:15, 25:1 to 1:10, from 25:1 to 1:5, 25:1 to 1:4, 25:1 to 1:3, 25:1 to 1:2, from 20:1 to 1:95, from 20:1 to 1:90, 20:1 to 1:85, from 20:1 to 1:80, from 20:1 to 1:75, from 20:1 to 1:70, from 20:1 to 1:65, from 20:1 to 1:60, from 20:1 to 1:55, from 20:1 to 1:50, from 20:1 to 1:45, from 20:1 to 1:40, from 20:1 to 1:35, from 20:1 to 1:30, from 20:1 to 1:25, from 20:1 to 1:15, from 20:1 to 1:10, from 20:1 to 1:5, from 20:1 to 1:4, from 20:1 to 1:3, from 20:1 to 1:2, 15:1 to 1:15, 15:1 to 1:95 from 15:1 to 1:90, from 15:1 to 1:85, from 15:1 to 1:80, from 15:1 to 1:75, from 15:1 to 1:70, from 15:1 to 1:65, from 15:1 to 1:60, from 15:1 to 1:55, from 15:1 to 1:50, from 15:1 to 1:45, from 15:1 to 1:40, from 15:1 to 1:35, from 15:1 to 1:30 from 15:1 to 1:25, from 15:1 to 1:20, from 15:1 to 1:10, from 15:1 to 1:5, from 15:1 to 1:4, from 15:1 to 1:3, from 15:1 to 1:2, from 10:1 to 1:10, from 10:1 to 1:95, from 10:1 to 1:90, from 10:1 to 1:85, from 10:1 to 1:80, from 10:1 to 1:75, from 0:1 to 1:70, from 10:1 to 1:65, from 10:1 to 1:60, from 10:1 to 1:55, from 10:1 to 1:50, from 10:1 to 1:45, from 10:1 to 1:40, from 10:1 to 1:35, from 10:1 to 1:30, from 10:1 to 1:25, from 10:1 to 1:20, from 10:1 to 1:15, from 10:1 to 1:5, from 10:1 to 1:4, from 10:1 to 1:3, from 10:1 to 1:2, from 5:1 to 1:5, from 5:1 to 1:95, from 5:1 to 1:90, from 5:1 to 1:85, from 5:1 to 1:80, from 5:1 to 1:75, from 5:1 to 1:70, 5:1 to 1:65, from 5:1 to 1:60, from 5:1 to 1:55, 5:1 to 1:50, from 5:1 to 1:45, from 5:1 to 1:40, from 5:1 to 1:35, from 5:1 to 1:30, from 5:1 to 1:25, from 5:1 to 1:20, from 5:1 to 1:15,5:1 to 1:10, from 5:1 to 1:4, from 5:1 to 1:3, from 5:1 to 1:2, from 4:1 to 1:4, from 4:1 to 1:95, from 4:1 to 1:90, from 4:1 to 1:85, from 4:1 to 1:80, from 4:1 to 1:75, from 4:1 to 1:70, 4:1 to 1:65, from 4:1 to 1:60, from 4:1 to 1:55, 4:1 to 1:50, from 4:1 to 1:45, 4:1 to 1:40, 4:1 to 1:35, from 4:1 to 1:30, from 4:1 to 1:25, from 4:1 to 1:20, from 4:1 to 1:15, from 4:1 to 1:10, from 4:1 to 1:5, from 4:1 to 1:3, from 4:1 to 1:2, from 3:1 to 1:3, from 3:1 to 1:95, from 3:1 to 1:90,from 3:1 to 1:85,from 3:1 to 1:80,from 3:1 to 1:75, from 3:1 to 1:70, from 3:1 to 1:65, from 3:1 to 1:60, from 3:1 to 1:55, 3:1 to 1:50, 3:1 to 1:45, from 3:1 to 1:40, from 3:1 to 1:35, from 3:1 to 1:30, from 3:1 to 1:25, from 3:1 to 1:20, from 3:1 to 1:15, from 3:1 to 1:10, from 3:1 to 1:5, from 3:1 to 1:4, from 3:1 to 1:2, 2:1 to 1:2, 2:1 to 1:95, 2:1 to 1:90, 2:1 to 1:85, 2:1 to 1:80, 2:1 to 1:75, 2:1 to 1:70, 2:1 to 1:65 from 2:1 to 1:60, 2:1 to 1:55, 2:1 to 1:50, 2:1 to 1:45, 2:1 to 1:40, 2:1 to 1:35, 2:1 to 1:30, 2:1 to 1:25, from 2:1 to 1:20, from 2:1 to 1:15, from 2:1 to 1:10, from 2:1 to 1:5, from 2:1 to 1:4, 2:1 to 1:3.

The compounds of formula (I) or active substances from the above group containing at least one with the main character of the centre, for example, may form a salt, e.g. the R, with strong inorganic acids, in particular mineral acids, for example, perarnau, sulfuric, hydrochloric, nitric, phosphoric or halogen acid, with strong organic carboxylic acids, such as unsubstituted or substituted, for example substituted by halogen alcancarao acids with 1-4 carbon atoms, in particular acetic acid, saturated or unsaturated dicarboxylic acids, e.g. oxalic, malonic, succinic, maleic, fumaric or phthalic acid, with hydroxycarbonate acids, e.g. ascorbic, lactic, malic, tartaric or citric acid, benzoic acid or organic the sulfonic acids, such as unsubstituted or substituted, for example substituted by halogen of alkanesulfonyl or arylsulfonate with 1-4 carbon atoms, in particular, with methanesulphonate or p-toluensulfonate. The compounds of formula (I) or active substances from the class of macrolides, carboxylates or other classes containing at least one acid group, for example, can form salts with bases, e.g. metal salts, such as alkali or alkaline earth metals, in particular sodium, potassium or magnesium, salts with ammonia, an organic amine, such as morpholine, piperidine, pyrrolidine, lower monoalkyl, dialkyl the min or trialkylamine, in particular, ethylamine, diethylamine, triethylamine or dimethylpropylene, or lower monohydroxylation, dihydroxyaluminum or trihydroxystilbene, in particular, monoethanolamine, diethanolamine or triethanolamine. Along with this, under certain conditions, the formation of the corresponding internal salts. In accordance with the invention are preferred agrokhimichesky preferred salt. Given the close relationship between the free compounds of formula (I) or the active ingredients of the above groups and their salts, any of the above and subsequent description mentions of free compounds of formula (I) or free active substances from the above group of class or their salts should be understood (if it is relevant and appropriate) so that we are talking about the appropriate salts, respectively, the free compounds of formula (I) or free active substances from the above group. This applies to tautomers of compounds of formula (I), respectively, of active substances of the above groups, as well as to the salts of the tautomers.

In accordance with the present invention the concept of "combination of active ingredients" used to refer to various combinations of compounds of formula I with active ingredients of the above groups, n is an example, in the form of individual ready-mix or intended for spraying the combined mixture of individual products individual active substances prepared, for example, in the tank, and also to denote the combined used of the individual active substances if consistently applied, for example, within a reasonable short period of time, for example, within a few hours or days. In accordance with a preferred sequence of application of the compounds of formula (I) and active ingredients of the above groups is not critical for the implementation of the present invention.

Using the proposed invention in combinations of active substances as insecticides consumption rates depending on the application, can vary within wide limits. When processing parts of plants, such as leaves, the rate of flow proposed in the invention combinations of active substances ranging from 0.1 to 10,000 g/ha, preferably from 10 to 1000 g/ha, particularly preferably from 50 to 300 g/ha (in case of use of the combinations specified by sprinkling or drip irrigation may reduce consumption norms, which primarily refers to the use of inert substrates like Rockwool or perlite), the WTO as in the processing of seed materials, it is from 2 to 200 g per 100 kg of seed material, preferably from 3 to 150 g per 100 kg of seed, particularly preferably from 2.5 to 25 g per 100 kg of seed, more preferably from 2.5 to 12.5 g per 100 kg seeds and soil from 0.1 to 10,000 g/ha, preferably from 1 to 5000 g/ha

Used in accordance with the present invention norms of consumption are not limited to the above intervals should be considered as examples.

,

and/or

esters of pyrimidifen

(2-50) R is chloro (4-[(4-chloro-α,α,α-Cryptor-3-tolyl)-oxy]-6-α,α,α-4-titrator-3-tolyl)oxy]pyrimidine),

(2-51) R means NO2(4-[(4-chloro-α,α,α-Cryptor-3-tolyl)-oxy]-6-[(α,α,α-Cryptor-4-nitro-3-tolyl)oxy]pyrimidine),

(2-52) R is bromo (4-[(4-chloro-α,α,α-Cryptor-3-tolyl)-oxy]-6-[(α,α,α-Cryptor-4-bromo-3-tolyl)oxy]pyrimidine),

known from international application WO 94/02470 and European patent application EP-A-883991 and/or

(2-53) cyanomethane acaricide IKA 2002, O-{(E)-2-(4-chlorophenyl)-2-cyano-1-[2-(trifluoromethyl)phenyl]ethynyl}-S-metallicar-NAT (known from international application WO 98/35935):

,

have a synergistic effect and is suitable for control of noxious animals. Unexpectedly it was found that the insecticidal and acaricidal action proposed in the invention kombinacijata substances is much greater than the sum of the actions of the individual active substances. Thus, we are talking about unexpected persistent synergistic effect, and not the simple summation of the individual effects.

The synergistic action proposed in the invention combinations of active substances containing a compound of the formula (I) and the active substance from the class of macrolides, carboxylates or other classes, allows you to extend the range of effectiveness of the compounds of formula (I) and the active substance from the class of macrolides, carboxylates or other classes primarily due to the reduction of the metered quantity and the broadening of the spectrum destroying pests. Thus, the use of the proposed invention in combinations of active substances containing a compound of the formula (I) and the active substance from the class of macrolides, carboxylates or other classes that can provide a high degree of protection of plants from pests, including in those cases, if the individual compounds included in the composition proposed in the invention combinations of active substances, do not show sufficient efficacy at low application rates.

In addition to the above synergistic actions proposed in the invention combination of active ingredients able to provide other unexpected benefits, including improved safety, reduced phytotoxicity,and, therefore, a higher tolerance of plants, the possibility of destruction pests at different stages of development, improvement of technological properties, for example, optimizing behavior during the shredding or mixing during storage or use insecticidal compounds, favorable biocidal action, including low concentrations, and, therefore, a high tolerance of warm-blooded animals, fish and plants, as well as the possibility of providing additional effects, such as effects inherent in the algaecides, anthelminticum, avicides, bactericides, fungicides, molluscicides, nematicides, means for activating the plants, rodenticides or virucidal.

In addition, it has been unexpectedly found that the proposed in the invention combination of active substances are particularly well suited for protection from damage by pests seed and/or shoots and leaves grown from the seeds of the plant. Thus, the proposed invention in the combination of active substances differ negligibly low phytotoxicity when applied to materials for the production of plants, compatibility with the soil (for example, lack of binding soil), the systemic exposure in the plant, the lack of adverse effects on germination and efficiency in teeniesnude cycle of the relevant pest.

Proposed in the invention combination of active substances in addition to at least one of the compounds of formula (I) contain at least one of the above active substances (2-1)to(2-53). Proposed in the invention combination of active substances preferably contain the compound of formula (I) and one compound of the above active substances (2-1)to(2-53). Also preferred are combinations of active substances which contain one compound of formula (I) and two compounds of the above active substances (2-1)to(2-53). Preferred are also mixtures containing two compounds of formula (I) and one of the above active substances (2-1)to(2-53).

The following is a preferred subgroup of compounds of the above formula (I)used in the present invention combinations of active substances together with at least one of the above active substances (2-1)to(2-53) except 4-{[(6-chloropyrid-3-yl)methyl](methyl)amino}furan-2(5H)-she 4-{[(6-chloropyrid-3-yl)methyl](cyclopropyl)amino}furan-2(5H)-it.

And preferably means 6-forperiod-3-yl, 6-chloropyrid-3-yl, 6-pampered-3-yl, 6-methylpiperid-3-yl, 6-triptoreline-3-yl, 6-cryptomaterial-3-yl, 6-chloro-1,4-pyridazin-3-yl, 6-methyl-1,4-pyridazin-3-yl, 2-chloro-1,3-thiazol-5-yl, 2-methyl-1,3-thiazol-5-yl, 2-Harper midin-5-yl, 2-cryptomaterial-5-yl, 5,6-debtor-pyrid-3-yl, 5-chloro-6-forperiod-3-yl, 5-bromo-6-forperiod-3-yl, 5-iodine-6-forperiod-3-yl, 5-fluoro-6-chloropyrid-3-yl, 5,6-dichlorine-3-yl, 5-bromo-6-chloropyrid-3-yl, 5-iodine-6-chloropyrid-3-yl, 5-the fluorine-6-pampered-3-yl, 5-chloro-6-pampered-3-yl, 5,6-dibromine-3-yl, 5-fluoro-6-jumpered-3-yl, 5-chloro-6-jumpered-3-yl, 5-bromo-6-jumpered-3-yl, 5-methyl-6-forperiod-3-yl, 5-methyl-6-chloropyrid-3-yl, 5-methyl-6-pampered-3-yl, 5-methyl-6-jumpered-3-yl, 5-deformity-6-fluoro-pyrid-3-yl, 5-deformity-6-chloropyrid-3-yl, 5-deformity-6-pampered-3-yl or 5-deformity-6-jumpered-3-yl.

R1preferably denotes optionally substituted by fluorine, alkyl with 1-5 carbon atoms, alkenyl with 2-5 carbon atoms, cycloalkyl with 3-5 carbon atoms, cycloalkenyl with 3-5 carbon atoms in cycloalkyl or alkoxy with 1-5 carbon atoms.

And especially preferably means 6-forperiod-3-yl, 6-chloropyrid-3-yl, 6-pampered-3-yl, 6-chloro-1,4-pyridazin-3-yl, 2-chloro-1,3-thia-Zol-5-yl, 2-chloropyrimidine-5-yl, 5-fluoro-6-chloropyrid-3-yl, 5,6-dichlorine-3-yl, 5-bromo-6-chloropyrid-3-yl, 5-fluoro-6-pampered-3-yl, 5-chloro-6-pampered-3-yl, 5,6-dibromine-3-yl, 5-methyl-6-chloro-pyrid-3-yl, 5-chloro-6-jumpered-3-yl or 5-deformity-6-chloropyrid-3-yl.

R1especially preferably means methyl, methoxy, ethyl, propyl, vinyl, allyl, propargyl, cyclopropyl, 2-foretel, 2,2-dottorati or 2-forciblepoppy.

And E. the e is more preferably means 6-forperiod-3-yl, 6-chloro-pyrid-3-yl, 6-pampered-3-yl, 5-fluoro-6-chloropyrid-3-yl, 2-chloro-1,3-thiazol-5-yl or 5,6-dichlorine-3-yl.

R1even more preferably means methyl, cyclopropyl, methoxy, 2-foradil or 2,2-dottorati.

And it is most preferable means 6-chloropyrid-3-yl or 5-fluoro-6-chloropyrid-3-yl.

R1most preferably means methyl, 2-foradil or 2,2-dottorati.

To emphasize the group of compounds of formula (I) balance As mean 6-chloropyrid-3-yl:

.

In another particularly recognise the group of compounds of formula (I) balance As mean 6-pampered-3-yl:

.

In another particularly recognise the group of compounds of formula (I) residue a represents 6-chloro-1,4-pyridazin-3-yl:

.

In another particularly recognise the group of compounds of formula (I) residue And means 2-chloro-1,3-thiazol-5-yl:

.

In another particularly recognise the group of compounds of formula (I) residue a represents 5-fluoro-6-chloropyrid-3-yl:

.

In another particularly recognise the group of compounds of formula (I) residue a represents 5-fluoro-6-pampered-3-yl:

.

In another particularly recognise the group of compounds of formula (I) residue And means 5,6-dichlorine-3-yl:

.

On another note g is the group of compounds of formula (I) residue R 1means methyl.

In another particularly recognise the group of compounds of formula (I) residue R1means ethyl.

In another particularly recognise the group of compounds of formula (I) residue R1means cyclopropyl.

In another particularly recognise the group of compounds of formula (I) residue R1mean 2-feratel.

In another particularly recognise the group of compounds of formula (I) residue R1means 2,2-dottorati.

The above balances that are used in General or in preferred embodiments, can in any way be combined with each other.

According to the invention preferred are the compounds of formula (I)containing a combination of the above preferred residues.

According to the invention particularly preferred are the compounds of formula (I)containing a combination of the above especially preferred residues.

According to the invention is even more preferred are the compounds of formula (I)containing a combination of the above more preferred residues.

To preferred subgroup of compounds of General formula (I) include compounds of formula (I-a):

,

in which

In means of pyrid-2-yl, pyrid-4-yl, pyrid-3-yl, optionally substituted in position 6 by fluorine, chlorine, bromine, stands, trifluoromethyl or triptorelin and, pyridazin-3-yl, optionally substituted in the 6 position by chlorine or stands, pyrazin-3-yl, 2-chloropyrazine-5-yl or 1,3-thiazol-6-yl, optionally substituted in position 2 by chlorine or stands, and

R2means halogenated, halogenoalkanes, halogenosilanes or halogennitroalkanes.

The following is the preferred substituents in the above and below for the compounds of formula (I-a).

In preferred means 6-forperiod-3-yl, 6-chloropyrid-3-yl, 6-pampered-3-yl, 6-methylpiperid-3-yl, 6-triptoreline-3-yl, 6-cryptomaterial-3-yl, 6-chloro-1,4-pyridazin-3-yl, 6-methyl-1,4-pyridazin-3-yl, 2-chloro-1,3-thiazol-5-yl or 2-methyl-1,3-thiazol-5-yl.

R2preferably means are replaced by fluorine, alkyl with 1-5 carbon atoms, alkenyl with 2-5 carbon atoms, cycloalkyl with 3-5 carbon atoms or cycloalkenyl with 3-5 carbon atoms in cycloalkyl.

In a particularly preferred means 6-forperiod-3-yl, 6-chloropyrid-3-yl, 6-pampered-3-yl, 6-chloro-1,4-pyridazin-3-yl or 2-chloro-1,3-thiazol-5-yl.

R2particularly preferably represents 2-foretel, 2,2-dottorati or 2-forciblepoppy.

In a more preferred means 6-chloropyrid-3-yl.

R2even more preferably denotes 2-foradil or 2,2-dottorati.

To emphasize the group of compounds of formula (I-a) the remainder In mean 6-chloropyrid-3-yl:

.

In another particularly recognise the group of compounds of formula (I-a) the remainder In mean 6-pampered-3-yl:

.

In another particularly recognise the group of compounds of formula (I-a) the remainder In mean 6-chloro-1,4-pyridazin-3-yl:

.

In another particularly recognise the group of compounds of formula (I-a) the remainder R2mean 2-feratel.

In another particularly recognise the group of compounds of formula (I-a) the remainder R2means 2,2-dottorati.

Another preferred subgroup of compounds of General formula (I) include compounds of formula (I-b):

,

in which

D is a residue of the formula:

,

in which X and Y are such as defined above,

and

R3means hydrogen, alkyl, alkenyl, quinil, cycloalkyl or alkoxy.

The following is the preferred substituents in the above and below for the compounds of formula (I-b).

D preferably means 5,6-diporphyrin-3-yl, 5-chloro-6-fluoro-pyrid-3-yl, 5-bromo-6-forperiod-3-yl, 5-iodine-6-forperiod-3-yl, 5-fluoro-6-chloropyrid-3-yl, 5,6-dichlorine-3-yl, 5-bromo-6-chloropyrid-3-yl, 5-iodine-6-chloropyrid-3-yl, 5-fluoro-6-brokered-3-yl, 5-chloro-6-bromo-pyrid-3-yl, 5,6-dibromine-3-yl, 5-fluoro-6-jumpered-3-yl, 5-chloro-6-jumpered-3-yl, 5-bromo-6-jumpered-3-yl, 5-methyl-6-forperiod-3-yl, 5-methyl-6-chloropyrid-3-yl, 5-methyl-6-pampered-3-yl, 5-IU the Il-6-iodine-pyrid-3-yl, 5-deformity-6-forperiod-3-yl, 5-deformity-6-chloropyrid-3-yl, 5-deformity-6-pampered-3-yl or 5-debtor-methyl-6-jumpered-3-yl.

R3preferably denotes alkyl with 1-4 carbon atoms, alkenyl with 2-4 carbon atoms, quinil with 2-4 carbon atoms or cycloalkyl with 3-4 carbon atoms.

D particularly preferably means 5-fluoro-6-chloropyrid-3-yl, 5,6-dichlorine-3-yl, 5-bromo-6-chloropyrid-3-yl, 5-fluoro-6-pampered-3-yl, 5-chloro-6-pampered-3-yl, 5,6-dibromine-3-yl, 5-methyl-6-chloropyrid-3-yl, 5-chloro-6-jumpered-3-yl or 5-deformity-6-chloropyrid-3-Il.

R3particularly preferably denotes alkyl with 1-4 carbon atoms.

D even more preferably means 5-fluoro-6-chloropyrid-3-yl or 5-fluoro-6-pampered-3-yl.

R3even more preferably means methyl, ethyl, propyl, vinyl, allyl, propargyl or cyclopropyl.

D is the most preferred means of 5-fluoro-6-chloropyrid-3-yl.

R3most preferably means methyl or cyclopropyl.

In another particularly recognise the group of compounds of formula (I-b) residue D is 5-fluoro-6-chloropyrid-3-yl:

In another particularly recognise the group of compounds of formula (I-b) residue D means 5,6-dichlorine-3-yl:

In another particularly recognise the group of compounds of formula (I-b) residue D means 5-bromo-6-chloropyrid-3-yl:

In another particularly recognise the group of compounds of formula (I-b) residue D is 5-methyl-6-chloro-pyrid-3-yl:

In another particularly recognise the group of compounds of formula (I-b) residue D is 5-fluoro-6-pampered-3-yl:

In another particularly recognise the group of compounds of formula (I-b) residue D is 5-chloro-6-pampered-3-yl:

In another particularly recognise the group of compounds of formula (I-b) residue D is 5-chloro-6-jumpered-3-yl:

.

In another particularly recognise the group of compounds of formula (I-b) the remainder R3means methyl.

In another particularly recognise the group of compounds of formula (I-b) the remainder R3means ethyl.

In another particularly recognise the group of compounds of formula (I-b) the remainder R3means cyclopropyl.

Another preferred subgroup of compounds of General formula (I) include compounds of formula (I-c):

,

in which

E. means a residue of the formula:

.

in which X and Y are such as defined above,

and

R4means halogenated, halogenoalkanes, halogenosilanes or halogennitroalkanes.

The following is the preferred substituents in the above and below for the compounds of formula (I-c).

E predpochtitelnye 5,6-diporphyrin-3-yl, 5-chloro-6-fluoro-pyrid-3-yl, 5-bromo-6-forperiod-3-yl, 5-iodine-6-forperiod-3-yl, 5-fluoro-6-chloropyrid-3-yl, 5,6-dichlorine-3-yl, 5-bromo-6-chloropyrid-3-yl, 5-iodine-6-chloropyrid-3-yl, 5-fluoro-6-pampered-3-yl, 5-chloro-6-bromine-pyrid-3-yl, 5,6-dibromine-3-yl, 5-fluoro-6-jumpered-3-yl, 5-chloro-6-jumpered-3-yl, 5-bromo-6-jumpered-3-yl, 5-methyl-6-forperiod-3-yl, 5-methyl-6-chloropyrid-3-yl, 5-methyl-6-pampered-3-yl, 5-methyl-6-iodine-pyrid-3-Il, 5-deformity-6-forperiod-3-yl, 5-deformity-6-chloropyrid-3-yl, 5-deformity-6-pampered-3-yl or 5-debtor-methyl-6-jumpered-3-yl.

R4preferably means are replaced by fluorine, alkyl with 1-5 carbon atoms, alkenyl with 2-5 carbon atoms, cycloalkyl with 3-5 carbon atoms or cycloalkenyl with 3-5 carbon atoms in cycloalkyl.

E particularly preferably represents 2-chloropyrimidine-5-yl, 5-fluoro-6-chloropyrid-3-yl, 5,6-dichlorine-3-yl, 5-bromo-6-chloropyrid-3-yl, 5-fluoro-6-pampered-3-yl, 5-chloro-6-pampered-3-yl, 5,6-dibromine-3-yl, 5-methyl-6-chloropyrid-3-yl, 5-chloro-6-jumpered-3-yl or 5-deformity-6-chloropyrid-3-yl.

R4particularly preferably represents 2-foretel, 2,2-dottorati or 2-forciblepoppy.

E even more preferably means 5-fluoro-6-chloropyrid-3-yl.

R4even more preferably denotes 2-foradil or 2,2-dottorati.

In another particularly recognise the group of compounds of formula (I-e) residue E means 5-fluoro-6-chloropyrid-3-yl:

In another particularly recognise the group of compounds of formula (I-c) residue E means 5,6-dichlorine-3-yl:

.

In another particularly recognise the group of compounds of formula (I-c) residue E means 5-bromo-6-chloropyrid-3-yl:

In another particularly recognise the group of compounds of formula (I-c) residue E means 5-methyl-6-chloropyrid-3-yl:

In another particularly recognise the group of compounds of formula (I-c) residue E means 5-fluoro-6-pampered-3-yl:

In another particularly recognise the group of compounds of formula (I-c) residue E means 5-chloro-6-pampered-3-yl:

In another particularly recognise the group of compounds of formula (I-c) residue E means 5-chloro-6-jumpered-3-yl:

In another particularly recognise the group of compounds of formula (I-c) residue R4mean 2-feratel.

In another particularly recognise the group of compounds of formula (I-c) residue R4means 2,2-dottorati.

To preferred subgroup of compounds of General formula (I) include compounds of formula (I-d):

,

in which

G means pyrid-2-yl, pyrid-4-yl, pyrid-3-yl, optionally substituted in position 6 by fluorine, chlorine, bromine, stands, trifluoromethyl or triptoreline, pyridazin-3-the l optionally substituted in the 6 position by chlorine or stands, pyrazin-3-yl, 2-chloropyrazine-6-yl or 1,3-thiazol-6-yl, optionally substituted in position 2 by chlorine or stands, and

R5means alkyl with 1-4 carbon atoms, alkenyl with 2-4 carbon atoms, quinil with 2-4 carbon atoms, cycloalkyl with 3-4 carbon atoms or alkoxy with 1-4 carbon atoms,

with the exception of 4-{[(6-chloropyrid-3-yl)methyl](methyl)amino}furan-2(5H)-she 4-{[(6-chloropyrid-3-yl)methyl](cyclopropyl)amino}furan-2(5H)-it.

The following is the preferred substituents in the above and below for the compounds of formula (I-d).

G means preferably 6-forperiod-3-yl, 6-chloropyrid-3-yl, 6-pampered-3-yl, 6-methylpiperid-3-yl, 6-triptoreline-3-yl, 6-cryptomaterial-3-yl, 6-chloro-1,4-pyridazin-3-yl, 6-methyl-1,4-pyridazin-3-yl, 2-chloro-1,3-thiazol-5-yl or 2-methyl-1,3-thiazol-5-yl.

R5preferably denotes alkyl with 1-4 carbon atoms, alkoxy with one carbon atom, alkenyl with 2-4 carbon atoms, quinil with 2-4 carbon atoms or cycloalkyl with 3-4 carbon atoms.

G particularly preferably means 6-forperiod-3-yl, 6-chloropyrid-3-yl, 6-pampered-3-yl, 6-chloro-1,4-pyridazin-3-yl or 2-chloro-1,3-thiazol-5-yl,

R5especially preferably means methyl, methoxy, ethyl, propyl, vinyl, allyl, propargyl or cyclopropyl.

G, even more preferably of oznacza the t 6-chloropyrid-3-yl.

R5even more preferably means methyl or cyclopropyl.

To emphasize the group of compounds of formula (I-d) residue G means 6-chloropyrid-3-yl:

In another particularly recognise the group of compounds of formula (I-d) residue G means 6-pampered-3-yl:

In another particularly recognise the group of compounds of formula (I-d) residue G means 6-chloro-1,4-pyridazin-3-yl:

In another particularly recognise the group of compounds of formula (I-d) residue G is 2-chloro-1,3-thiazol-5-yl:

In another particularly recognise the group of compounds of formula (I-d) residue G means 6-forperiod-3-yl:

In another particularly recognise the group of compounds of formula (I-d) residue G means 6-triptoreline-3-yl:

In another particularly recognise the group of compounds of formula (I-d) residue G means 6-forperiod-3-yl:

In another particularly recognise the group of compounds of formula (I-d) residue R5means methyl.

In another particularly recognise the group of compounds of formula (I-d) residue R5means cyclopropyl.

Examples of compounds of General formula (I) are;

- known from international application WO 2007/115644 compound of the formula (I-1), 4-{[(6-pampered-3-yl)IU is Il](2-foradil)amino}-furan-2(5H)-he:

,

- known from international application WO 2007/115644 compound of the formula (I-2), 4-{[(6-forperiod-3-yl)methyl](2,2-dottorati)amino}-furan-2(5H)-he:

,

- known from international application WO 2007/115644 compound of the formula (I-3), 4-{[(2-chloro-1,3-thiazol-5-yl)methyl](2-foradil)amino}-furan-2(5H)-he:

,

- known from international application WO 2007/115644 compound of the formula (I-4), 4-{[(6-chloropyrid-3-yl)methyl](2-foradil)amino}-furan-2(5H)-he:

,

- known from international application WO 2007/115644 compound of the formula (I-5), 4-{[(6-chloropyrid-3-yl)methyl](2,2-dottorati)amino}-furan-2(5H)-he:

,

- known from international application WO 2007/115643 compound of the formula (I-6), 4-{[(6-chloro-5-forperiod-3-yl)methyl](methyl)amino}-furan-2(5H)-he:

,

- known from international application WO 2007/115646 compound of the formula (I-7), 4-{[(5,6-dichlorine-3-yl)methyl](2-foradil)amino}-furan-2(5H)-he:

,

- known from international application WO 2007/115643 compound of the formula (I-8), 4-{[(6-chloro-5-forperiod-3-yl)methyl](cyclopropyl)-amino}furan-2(5H)-he:

,

Proposed in the invention combination of active substances preferably contain at least one of the compounds of formula (I), using the data from the group including compounds of the above formula (I-a), (I-b), (I-c) or (I-d), except 4-{[(6-chloropyrid-3-yl)methyl]-(methyl)amino}furan-2(5H)-she 4-{[(6-chloropyrid-3-yl)methyl] (cyclopropyl)amino}furan-2(5H)-it, and one of the above active substances (2-1)-(2-53).

In addition, the proposed in the invention combination of active substances preferably contain at least one of the compounds of formula (I)selected from the group comprising compounds of the above formula (I-a), (I-b) or (I-c) and one of the above active substances (2-1)to(2-53).

Proposed in the invention combination of active substances, particularly preferably contain at least one of the compounds of formula (I), in which the residue And is selected from the group comprising 6-forperiod-3-yl, 6-chloropyrid-3-yl, 6-pampered-3-yl, 5-fluoro-6-chloropyrid-3-yl, 2-chloro-1,3-thiazol-5-yl and 5,6-dichlorine-3-yl, and the remainder R1selected from the group comprising methyl, cyclopropyl, methoxy, 2-foradil and 2,2-dottorati, except 4-{[(6-chloropyrid-3-yl)methyl](methyl)amino}furan-2(5H)-she 4-{[(6-chloropyrid-3-yl)methyl](cyclopropyl)amino}furan-2(5H)-it, and one of the above active substances (2-1)to(2-53).

Proposed in the invention combination of active substances even more preferably contain at least one compound of formula (I)selected from the group comprising compounds of the formulae (I-1), (I-2) (I-3), (I-4), (I-5), (I-6), (I-7) and (I-8), and one of the above active substances (2-1)to(2-53).

Table 1 shows the combinations of active substances, each of which corresponds to an even more preferred variant embodiment of the invention.

Table 1
The components of the combination of active substances
The number of combinations of active substancesThe compound of formula (I)Connection groups 2
1-1I-1+(2-1) spinosad
1-2I-1+(2-2) spinetoram
1-3I-1+(2-3) abamectin
1-4I-1+(2-4) emamectin-benzoate
1-5I-1+(2-5) milbemectin
1-6 I-1+(2-6) leemartin
1-7I-1+(2-7) ivermectin
1-8I-1+(2-8) indoxacarb
1-9I-1+(2-9) fipronil
1-10I-1+(2-10) ethiprole
1-11I-1+(2-11) perflubron
1-12I-1+(2-12) periphral
1-13I-1+(2-13) bifenazate
1-14I-1+(2-14) chlorfenapyr
1-15I-1+(2-15) diafenthiuron
1-16I-1 +(2-16) azocyclotin
1-17I-1+(2-17) cyhexatin
1-18I-1+(2-18) fenbutatin oxide
1-19I-1+(2-19) tebufenpyrad
1-20I-1+(2-20) fenpyroximate
1-21I-1+(2-21) canoperate
1-22I-1+(2-22) clofentezine
1-23I-1+(2-23) defloweration
1-24I-1+(2-24) propargite
1-25I-1+(2-25) chinomethionat
1-26I-1(2-26) bromopropylate
1-27I-1+(2-27) dicofol
1-28I-1+(2-28) tetradifon
1-29I-1+(2-29) titlemotion
1-30I-1+(2-30) amitraz
1-31I-1+(2-31) cyromazine
1-32I-1+(2-32) exitosos
1-33I-1+(2-33) endosulfan
1-34I-1+(2-34) pyrimidifen
1-35I-1+(2-35) thuringiensis
1-36I-1+ (2-36) flociprin
1-37I-1+(2-37) acequinocyl
1-38I-1+(2-38) etoxazole
1-39I-1+(2-39) fenazaquin
1-40I-1+(2-40) pyridaben
1-41I-1+(2-41) triuralin
1-42I-1+(2-42) flonicamid
1-43I-1+(2-43) buprofezin
1-44I-1+(2-44) pyridalyl
1-45I-1+(2-45) pymetrozine
1-46I-1+(2-46) periplo Vinson
1-47I-1+(2-47) rynaxypyr
1-48I-1+(2-48) Casimir
1-49I-1+(2-49) metaflumizone
1-50I-1+(2-50) (4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-4-titrator-3-tolyl)oxy]pyrimidine)
1-51I-1+(2-51) 4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-nitro-3-tolyl)oxy]pyrimidine
1-52I-1+(2-52) 4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-bromo-3-tolyl)oxy]pyrimidine
1-53I-1+(2-53) IKA 2002

Table 2 shows the combinations of active substances, each of which corresponds to a preferred variant embodiment of the invention.

Table 2
The components of the combination of active substances
The number of combinations of active substancesThe compound of formula (I)Connection groups 2
2-1I-2+(2-1) spinosad
2-2I-2+(2-2) spinetoram
2-3I-2+(2-3) abamectin
2-4I-2+(2-4) emamectin-benzoate
2-5I-2+(2-5) milbemectin
2-6I-2+(2-6) leemartin
2-7I-2+(2-7) ivermectin
2-8I-2+2-9I-2+(2-9) fipronil
2-10I-2+(2-10) ethiprole
2-11I-2+(2-11) perflubron
2-12I-2+(2-12) periphral
2-13I-2+(2-13) bifenazate
2-14I-2+(2-14) chlorfenapyr
2-15I-2+(2-15) diafenthiuron
2-16I-2+(2-16) azocyclotin
2-17I-2+(2-17) cyhexatin
2-18I-2+(2-18) fenbutatin
2-19I-2+(2-19) tebufenpyrad
2-20I-2+(2-20) fenpyroximate
2-21I-2+(2-21) canoperate
2-22I-2+(2-22) clofentezine
2-23I-2+(2-23) defloweration
2-24I-2+(2-24) propargite
2-25I-2+(2-25) chinomethionat
2-26I-2+(2-26) bromopropylate
2-27I-2+(2-27) dicofol
2-28I-2+(2-28) tetradifon
2-29I-2+(2-29) titlemotion
2-30I-2+(2-30) amitraz
2-31I-2+(2-31) cyromazine
2-32I-2+(2-32) exitosos
2-33I-2+(2-33) endosulfan
2-34I-2+(2-34) pyrimidifen
2-35I-2+(2-35) thuringiensis
2-36I-2+(2-36) flociprin
2-37I-2+(2-37) acequinocyl
2-38I-2+(2-38) etoxazole
2-39I-2+(2-39) fenazaquin
2-40I-2+(2-40) pyridaben
2-41I-2+(2-41) triuralin
2-42I-2+(2-42) flonicamid
2-43I-2+(2-43) buprofezin
2-44I-2+(2-44) pyridalyl
2-45I-2+(2-45) pymetrozine
2-46I-2+(2-46) periglaciation
2-47I-2+(2-47) rynaxypyr
2-48I-2+(2-48) Casimir
2-49 I-2+(2-49) metaflumizone
2-50I-2+(2-50) (4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-4-titrator-3-tolyl)oxy]pyrimidine)
2-51I-2+(2-51) 4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-nitro-3-tolyl)oxy]pyrimidine
2-52I-2+(2-52) 4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-bromo-3-tolyl)oxy]pyrimidine
2-53I-2+(2-53) IKA 2002

Table 3 shows the combinations of active substances, each of which corresponds to a preferred variant embodiment of the invention.

td align="left"> I-3 +
Table 3
The components of the combination of active substances
The number of combinations of active substancesThe compound of formula (I)Compound g is uppi 2
3-1I-3+(2-1) spinosad
3-2I-3+(2-2) spinetoram
3-3I-3+(2-3) abamectin
3-4I-3+(2-4) emamectin-benzoate
3-5I-3+(2-5) milbemectin
3-6I-3+(2-6) leemartin
3-7I-3+(2-7) ivermectin
3-8I-3+(2-8) indoxacarb
3-9I-3+(2-9) fipronil
3-10I-3+(2-10) ethiprole
3-11I-3+(2-11) perflubron
3-12I-3+(2-12) periphral
3-13I-3+(2-13) bifenazate
3-14I-3+(2-14) chlorfenapyr
3-15I-3+(2-15) diafenthiuron
3-16I-3+(2-16) azocyclotin
3-17I-3+(2-17) cyhexatin
3-18I-3+(2-18) fenbutatin oxide
3-19I-3+.(2-19) tebufenpyrad
3-20I-3+(2-20) fenpyroximate
3-21I-3+(2-21) canoperate
3-22I-3+(2-22) clofentezine
3-23I-3+(2-23) defloweration
3-24I-3+(2-24) propargite
3-25I-3+(2-25) chinomethionat
3-26I-3+(2-26) bromopropylate
3-27I-3+(2-27) dicofol
3-28I-3+(2-28) tetradifon
3-29I-3+(2-29) titlemotion
3-30I-3+(2-30) amitraz
3-31+(2-31) cyromazine
3-32I-3+(2-32) exitosos
3-33I-3+(2-33) endosulfan
3-34I-3+(2-34) pyrimidifen
3-35I-3+(2-35) thuringiensis
3-36I-3+(2-36) flociprin
3-37I-3+(2-37) acequinocyl
3-38I-3+(2-38) etoxazole
3-39I-3+(2-39) fenazaquin
3-40I-3+(2-40) pyridaben
3-41I-3(2-41) triuralin
3-42I-3+(2-42) flonicamid
3-43I-3+(2-43) buprofezin
3-44I-3+(2-44) pyridalyl
3-45I-3+(2-45) pymetrozine
3-46I-3+(2-46) periglaciation
3-47I-3+(2-47) rynaxypyr
3-48I-3+(2-48) Casimir
3-49I-3+(2-49) metaflumizone
3-50I-3+(2-50) (4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-4-titrator-3-tolyl)oxy]pyrimidine)
3-51 I-3+(2-51) 4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-nitro-3-tolyl)oxy]pyrimidine
3-52I-3+(2-52) 4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-bromo-3-tolyl)oxy]pyrimidine
3-53I-3+(2-53) IKA 2002

Table 4 shows the combinations of active substances, each of which corresponds to a preferred variant embodiment of the invention.

Table 4
The components of the combination of active substances
The number of combinations of active substancesThe compound of formula (I)Connection groups 2
4-1I-4+(2-1) spinosad
4-2I-4+(2-2) spinetoram
4-3 I-4+(2-3) abamectin
4-4I-4+(2-4) emamectin-benzoate
4-5I-4+(2-5) milbemectin
4-6I-4+(2-6) leemartin
4-7I-4+(2-7) ivermectin
4-8I-4+(2-8) indoxacarb
4-9I-4+(2-9) fipronil
4-10I-4+(2-10) ethiprole
4-11I-4+(2-11) perflubron
4-12I-4+(2-12) periphral
4-13I-4 +(2-13) bifenazate
4-14I-4+(2-14) chlorfenapyr
4-15I-4+(2-15) diafenthiuron
4-16I-4+(2-16) azocyclotin
4-17I-4+(2-17) cyhexatin
4-18I-4+(2-18) fenbutatin oxide
4-19I-4+(2-19) tebufenpyrad
4-20I-4+(2-20) fenpyroximate
4-21I-4+(2-21) canoperate
4-22I-4+(2-22) clofentezine
4-23I-4 +(2-23) defloweration
4-24I-4+(2-24) propargite
4-25I-4+(2-25) chinomethionat
4-26I-4+(2-26) bromopropylate
4-27I-4+(2-27) dicofol
4-28I-4+(2-28) tetradifon
4-29I-4+(2-29) titlemotion
4-30I-4+(2-30) amitraz
4-31I-4+(2-31) cyromazine
4-32I-4+(2-32) exitosos
4-33I-4+ (2-33) endosulfan
4-34I-4+(2-34) pyrimidifen
4-35I-4+(2-35) thuringiensis
4-36I-4+(2-36) flociprin
4-37I-4+(2-37) acequinocyl
4-38I-4+(2-38) etoxazole
4-39I-4+(2-39) fenazaquin
4-40I-4+(2-40) pyridaben
4-41I-4+(2-41) triuralin
4-42I-4+(2-42) flonicamid
4-43I-4+(2-43) Boo is Riesen
4-44I-4+(2-44) pyridalyl
4-45I-4+(2-45) pymetrozine
4-46I-4+(2-46) periglaciation
About 4-47I-4+(2-47) rynaxypyr
4-48I-4+(2-48) Casimir
4-49I-4+(2-49) metaflumizone
4-50I-4+(2-50) (4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-4-titrator-3-tolyl)oxy]pyrimidine)
4-51I-4+(2-51) 4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-nitro-3-tolyl)oxy]pyrimidine
4-52I-4+(2-52) 4-[(4-chloro-α,α,α-trift the R-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-bromo-3-tolyl)oxy]pyrimidine
4-53I-4+(2-53) IKA 2002

Table 5 shows the combination of active substances, each of which corresponds to a preferred variant embodiment of the invention.

Table 5
The components of the combination of active substances
The number of combinations of active substancesThe compound of formula (I)Connection groups 2
5-1I-5+(2-1) spinosad
5-2I-5+(2-2) spinetoram
5-3I-5+(2-3) abamectin
5-4I-5+(2-4) emamectin-benzoate
5-5I-5+(2-5) milbemectin
5-6I-5+(2-6) leemartin
5-7I-5+(2-7) ivermectin
5-8I-5+(2-8) indoxacarb
5-9I-5+(2-9) fipronil
5-10I-5+(2-10) ethiprole
5-11I-5+(2-11) perflubron
5-12I-5+(2-12) periphral
5-13I-5+(2-13) bifenazate
5-14I-5+(2-14) chlorfenapyr
5-15I-5+(2-15) diafenthiuron
5-16I-5+(2-16) azocyclotin
5-17I-5+(2-17) cyhexatin
5-18I-5+(2-18) fenbutatin oxide
5-19I-5+(2-19) tebufenpyrad
5-20I-5+(2-20) fenpyroximate
5-21I-5+(2-21) canoperate
5-22I-5+(2-22) clofentezine
5-23I-5+(2-23) defloweration
5-24I-5+(2-24) propargite
5-25I-5+(2-25) chinomethionat
I-5+(2-26) bromopropylate
5-27I-5+(2-27) dicofol
5-28I-5+(2-28) tetradifon
5-29I-5+(2-29) titlemotion
5-30I-5+(2-30) amitraz
5-31I-5+(2-31) cyromazine
5-32I-5+(2-32) exitosos
5-33I-5+(2-33) endosulfan
5-34I-5+(2-34) pyrimidifen
5-35I-5+(2-35) thuringiensis
5-36 I-5+(2-36) flociprin
5-37I-5+(2-37) acequinocyl
5-38I-5+(2-38) etoxazole
5-39I-5+(2-39) fenazaquin
5-40I-5+(2-40) pyridaben
5-41I-5+(2-41) triuralin
5-42I-5+(2-42) flonicamid
5-43I-5+(2-43) buprofezin
5-44I-5+(2-44) pyridalyl
5-45I-5+(2-45) pymetrozine
5-46I-5 +(2-46) periglaciation
5-47I-5+(2-47) rynaxypyr
5-48I-5+(2-48) Casimir
5-49I-5+(2-49) metaflumizone
5-50I-5+(2-50) (4-[(4-chloro-α,α,α-Cryptor-3-tol yl)oxy]-6-[(α,α,α-4-titrator-3-tolyl)oxy]pyrimidine)
5-51I-5+(2-51) 4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-nitro-3-tolyl)oxy]pyrimidine
5-52I-5+(2-52) 4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-bromo-3-tolyl)oxy]pyrimidine
5-53I-5+(2-53) IKA 2002

Table 6 shows the combinations of active substances, each of which corresponds to a preferred variant embodiment of the invention.

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Table 6
The components of the combination of active substances
The number of combinations of active substancesThe compound of formula (I)Connection groups 2
6-1I-6+(2-1) spinosad
6-2I-6+(2-2) spinetoram
6-3I-6+(2-3) abamectin
6-4I-6+(2-4) emamectin-benzoate
6-5I-6+(2-5) milbemectin
6-6I-6+(2-6) leemartin
6-7I-6+(2-7) ivermectin
6-8 I-6+(2-8) indoxacarb
6-9I-6+(2-9) fipronil
6-10I-6+(2-10) ethiprole
6-11I-6+(2-11) perflubron
6-12I-6+(2-12) periphral
6-13I-6+(2-13) bifenazate
6-14I-6+(2-14) chlorfenapyr
6-15I-6+(2-15) diafenthiuron
6-16I-6+(2-16) azocyclotin
6-17I-6+(2-17) cyhexatin
6-18 I-6+(2-18) fenbutatin oxide
6-19I-6+(2-19) tebufenpyrad
6-20I-6+(2-20) fenpyroximate
6-21I-6+(2-21) canoperate
6-22I-6+(2-22) clofentezine
6-23I-6+(2-23) defloweration
6-24I-6+(2-24) propargite
6-25I-6+(2-25) chinomethionat
6-26I-6+(2-26) bromopropylate
6-27I-6+(2-27) dicofol
6-28 I-6+(2-28) tetradifon
6-29I-6+(2-29) titlemotion
6-30I-6+(2-30) amitraz
6-31I-6+(2-31) cyromazine
6-32I-6+(2-32) exitosos
6-33I-6+(2-33) endosulfan
6-34I-6+(2-34) pyrimidifen
6-35I-6+(2-35) thuringiensis
6-36I-6+(2-36) flociprin
6-37I-6+(2-37) acequinocyl
6-38I-6 +(2-38) etoxazole
6-39I-6+(2-39) fenazaquin
6-40I-6+(2-40) pyridaben
6-41I-6+(2-41) triuralin
6-42I-6+(2-42) flonicamid
6-43I-6+(2-43) buprofezin
6-44I-6+(2-44) pyridalyl
6 : 45 a.m.I-6+(2-45) pymetrozine
6-46I-6+(2-46) periglaciation
6-47I-6+(2-47) rynaxypyr
Onset 6 to 48I-6+ (2-48) Casimir
Have 6 to 49I-6+(2-49) metaflumizone
6-50I-6+(2-50) (4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-4-titrator-3-tolyl)oxy]pyrimidine)
6-51I-6+(2-51) 4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-nitro-3-tolyl)oxy]pyrimidine
6-52I-6+(2-52) 4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-bromo-3-tolyl)oxy]pyrimidine
6 to 53I-6+(2-53) IKA 2002

Table 7 summarizes the combinations of active substances, each of which corresponds to a preferred variant embodiment of the invention.

td align="left"> (2-20) fenpyroximate 7-41
Table 7
The components of the combination of active substances
The number of combinations of active substancesConnect four is ula (I) Connection groups 2
7-1I-7+(2-1) spinosad
7-2I-7+(2-2) spinetoram
7-3I-7+(2-3) abamectin
7-4I-7+(2-4) emamectin-benzoate
7-5I-7+(2-5) milbemectin
7-6I-7+(2-6) leemartin
7-7I-7+(2-7) ivermectin
7-8I-7+(2-8) indoxacarb
7-9I-7+(2-9) fipronil
7-10I-7 +(2-10) ethiprole
7-11I-7+(2-11) perflubron
7-12I-7+(2-12) periphral
7-13I-7+(2-13) bifenazate
7-14I-7+(2-14) chlorfenapyr
7-15I-7+(2-15) diafenthiuron
7-16I-7+(2-16) azocyclotin
7-17I-7+(2-17) cyhexatin
7-18I-7+(2-18) fenbutatin oxide
7-19I-7+(2-19) tebufenpyrad
7-20I-7+
7-21I-7+(2-21) canoperate
7-22I-7+(2-22) clofentezine
7-23I-7+(2-23) defloweration
7-24I-7+(2-24) propargite
7-25I-7+(2-25) chinomethionat
7-26I-7+(2-26) bromopropylate
7-27I-7+(2-27) dicofol
7-28I-7+(2-28) tetradifon
7-29I-7+(2-29) titlemotion
7-30I-7+
7-31I-7+(2-31) cyromazine
7-32I-7+(2-32) exitosos
7-33I-7+(2-33) endosulfan
7-34I-7+(2-34) pyrimidifen
7-35I-7+(2-35) thuringiensis
7-36I-7+(2-36) flociprin
7-37I-7+(2-37) acequinocyl
7-38I-7+(2-38) etoxazole
7-39I-7+(2-39) fenazaquin
7-40I-7+(2-40) pyridaben
I-7+(2-41) triuralin
7-42I-7+(2-42) flonicamid
7-43I-7+(2-43) buprofezin
7-44I-7+(2-44) pyridalyl
7-45I-7+(2-45) pymetrozine
7-46I-7+(2-46) periglaciation
7-47I-7+(2-47) rynaxypyr
7-48I-7+(2-48) Casimir
7 to 49I-7+(2-49) metaflumizone
7-50I-7+(2-50) (4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-4-thecraft the R-3-tolyl)oxy]pyrimidine)
7-51I-7+(2-51) 4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-nitro-3-tolyl)oxy]pyrimidine
7-52I-7+(2-52) 4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-bromo-3-tolyl)oxy]pyrimidine
7-53I-7+(2-53) IKA 2002

Table 8 shows the combination of active substances, each of which corresponds to a preferred variant embodiment of the invention.

tr> + (2-52) 4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-bromo-3-tolyl)oxy]pyrimidine
Table 8
The components of the combination of active substances
The number of combinations of active substancesThe compound of formula (I)Connection groups 2
8-1I-8+(2-1) spinosad
8-2I-8+(2-2) spinetoram
8-3I-8+(2-3) abamectin
8-4I-8+(2-4) emamectin-benzoate
8-5I-8+(2-5) milbemectin
8-6I-8+(2-6) leemartin
8-7I-8+(2-7) ivermectin
8-8I-8+(2-8) indoxacarb
8-9I-8+(2-9) fipronil
8-10I-8+(2-10) ethiprole
8-11I-8+(2-11) perflubron
8-12I-8+(2-12) periphral
8-13I-8+(2-13) bifenazate
8-14I-8+(2-14) chlorfenapyr
8-15I-8+(2-15) diafenthiuron
8-16I-8+(2-16) azocyclotin
8-17I-8+(2-17) cyhexatin
8-18I-8+(2-18) fenbutatin oxide
8-19I-8+(2-19) tebufenpyrad
8-20I-8+(2-20) fenpyroximate
8-21I-8+(2-21) canoperate
8-22I-8+(2-22) clofentezine
8-23I-8+(2-23) defloweration
8-24I-8+(2-24) propargite
8-25I-8+(2-25) chinomethionat
8-26I-8+(2-26) bromopropylate
8-27I-8+(2-27) dicofol
8-28I-8+(2-28) tetradifon
8-29I-8+(2-29) titlemotion
8-30I-8+(2-30) amitraz
8-31I-8+(2-31) cyromazine
8-32I-8+(2-32) exitosos
8-33 I-8+(2-33) endosulfan
8-34I-8+(2-34) pyrimidifen
8-35I-8+(2-35) thuringiensis
8-36I-8+(2-36) flociprin
8-37I-8+(2-37) acequinocyl
8-38I-8+(2-38) etoxazole
8-39I-8+(2-39) fenazaquin
8-40I-8+(2-40) pyridaben
8-41I-8+(2-41) triuralin
8-42I-8+(2-42) flonicamid
8-43I-8(2-43) buprofezin
8-44I-8+(2-44) pyridalyl
8-45I-8+(2-45) pymetrozine
8-46I-8+(2-46) periglaciation
8-47I-8+(2-47) rynaxypyr
8-48I-8+(2-48) Casimir
8-49I-8+(2-49) metaflumizone
8-50I-8+(2-50) (4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-4-titrator-3-tolyl)oxy]pyrimidine)
8-51I-8+(2-51) 4-[(4-chloro-α,α,α-Cryptor-3-tolyl)oxy]-6-[(α,α,α-Cryptor-4-nitro-3-tolyl)oxy]pyrimidine
8-52I-8+
8-53I-8+(2-53) IKA 2002

Especially high synergistic effect have proposed in the invention combination, active substances which are in a weight ratio to each other. However, this does not exclude the possibility of varying the mass ratio of active ingredients in the respective combinations in a fairly wide range. Proposed in the invention combination, containing the active substance of the formula (I) and one of the above active substances (2-1)to(2-53), are generally characterized by the following mass ratios of components:

the preferred interval of mass ratios from 125:1 to 1:125,

particularly preferred interval of mass ratios from 25:1 to 1:25.

Under the mass ratio of the components involve the mass ratio of the compounds of formula (I) to the mass of one of the active substances (2-1)to(2-53). Below is a list of possible intervals of the ratios between the compound of formula (I) and one of the above active substances (2-1)to(2-53) in ascending order of preference: from 95:1 to 1:95, 95:1 to 1:90, from 95:1 to 1:85, 95:1 to 1:80, from 95:1 to 1:75, the t 95:1 to 1:70, from 95:1 to 1:65, from 95:1 to 1:60, from 95:1 to 1:55, from 95:1 to 1:50, from 95:1 to 1:45, 95:1 to 1:40, from 95:1 to 1:35, from 95:1 to 1:30, 95:1 to 1:25, 95:1 to 1:20, 95:1 to 1:15, from 95:1 to 1:10, 95:1 to 1:5, 95:1 to 1:4, 95:1 to 1:3, 95:1 to 1:2, 90:1 to 1:90, from 90:1 to 1:95, from 90:1 to 1:85, 90:1 to 1:80, from 90:1 to 1:75, from 90:1 to 1:70, 90:1 to 1:65, from 90:1 to 1:60, from 90:1 to 1:55, from 90:1 to 1:50, 90:1 to 1:45, from 90:1 to 1:40, 90:1 to 1:35, from 90:1 to 1:30, 90:1 to 1:25, 90:1 to 1:20, 90:1 to 1:1.5, 90:1 to 1:10, 90:1 to 1:5, 90:1 to 1:4, 90:1 to 1:3, 90:1 to 1:2, 85:1 to 1:85, 85:1 to 1:95, from 85:1 to 1:90, 85:1 to 1:80, 85:1 to 1:75, from 85:1 to 1:70, 85:1 to 1:65, from 85:1 to 1:60, from 85:1 to 1:55, from 85:1 to 1:50, from 85:1 to 1:45, from 85:1 to 1:40, from 85:1 to 1:35, from 85:1 to 1:30, 85:1 to 1:25, 85:1 to 1:20, 85:1 to 1:15, 85:1 to 1:10, 85:1 to 1:5, 85:1 to 1:4, 85:1 to 1:3, 85:1 to 1:2, 80:1 to 1:80, from 80:1 to 1:95, from 80:1 to 1:90, from 80:1 to 1:85, from 80:1 to 1:75, from 80:1 to 1:70, from 80:1 to 1:65, from 80:1 to 1:60, from 80:1 to 1:55, from 80:1 to 1:50, 80:1 to 1:45, from 80:1 to 1:40, 80:1 to 1:35, from 80:1 to 1:30, 80:1 to 1:25, 80:1 to 1:20, 80:1 to 1:15, 80:1 to 1:10, from 80:1 to 1:5, 80:1 to 1:4, 80:1 to 1:3, 80:1 to 1:2, 75:1 to 1:75, from 75:1 to 1:95, from 75:1 to 1:90, from 75:1 to 1:85, from 75:1 to 1:80, 75:1 to 1:70, 75:1 to 1:65 from 75:1 to 1:60, from 75:1 to 1:55 from 75:1 to 1:50, 75:1 to 1:45, from 75:1 to 1:40, 75:1 to 1:35, 75:1 to 1:30, 75:1 to 1:25, 75:1 to 1:20, 75:1 to 1:15, 75:1 to 1:10, from 75:1 to 1:5, 75:1 to 1:4, 75:1 to 1:3, 75:1 to 1:2, 70:1 to 1:70, 70:1 to 1:95, from 70:1 to 1:90, from 70:1 to 1:85, from 70:1 to 1:80, from 70:1 to 1:75, from 70:1 to 1:65, from 70:1 to 1:60, from 70:1 to 1:55 from 70:1 to 1:50, 70:1 to 1:45, from 70:1 to 1:40, from 70:1 to 1:35, 70:1 to 1:30, 70:1 to 1:25, 70:1 to 1:20, 70:1 to 1:15, 70:1 to 1:10, 70:1 to 1:5, 70:1 to 1:4, 70:1 to 1:3, 70:1 to 1:2, 65:1 to 1:65, from 65:1 to 1:95, 65:1 to 1:90, 65:1 to 1:85, 65:1 to 1:80, 65:1 to 1:75, 65:1 to 1:70, 65:1 to 1:60, 65:1 to 1:55 from 65:1 to 1:50, 65:1 to 1:45, 65:1 to 1:40, 65:1 to 1:35, 65:1 to 1:30, 65:1 to 1:25, 65:1 to 1:20, 65:1 to 1:15, 65:1 to 1:10, 65:1 to 1:5, 65:1 to 1:4, 65:1 to 1:3, 65:1 to 1:2, 60:1 to 1:60, 60:1 to 1:95, from 60:1 to 1:90, from 60:1 to 1:85, from 60:1 to 1:80, from 60:1 to 1:75, from 60:1 to 1:70, 60:1 to 1:65, from 60:1 to 1:55 from 60:1 to 1:50, 60:1 to 1:45, from 60:1 to 1:40, 60:1 to 1:35, 60:1 to 1:30, 60:1 to 1:25, 60:1 to 1:20, 60:1 to 1:15, 60:1 to 1:10, 60:1 to 1:5, 60:1 to 1:4, 60:1 to 1:3, 60:1 to 1:2, 55:1 to 1:55 from 55:1 to 1:95, from 55:1 to 1:90, from 55:1 to 1:85, from 55:1 to 1:80, from 55:1 to 1:75, from 55:1 to 1:70, from 55:1 to 1:65, from 55:1 to 1:60, from 55:1 to 1:50, 55:1 to 1:45, from 55:1 to 1:40, from 55:1 to 1:35, from 55:1 to 1:30, from 55:1 to 1:25, 55:1 to 1:20, 55:1 to 1:15, 55:1 to 1:10, 55:1 to 1:5, 55:1 to 1:4, 55:1 to 1:3, 55:1 to 1:2, from 50:1 to 1:95, from 50:1 to 1:90, from 50:1 to 1:85, from 50:1 to 1:80, 50:1 to 1:75, 50:1 to 1:70, 50:1 to 1:65, from 50:1 to 1:60, 50:1 to 1:55 from 50:1 to 1:45, from 50:1 to 1:40, 50:1 to 1:35, from 50:1 to 1:30 from 50:1 to 1:25, from 50:1 to 1:20, from 50:1 to 1:15, 50:1 to 1:10, from 50:1 to 1:5, 50:1 to 1:4, 50:1 to 1:3, from 50:1 to 1:2, 45:1 to 1:45, from 45:1 to 1:95, from 45:1 to 1:90, from 45:1 to 1:85, from 45:1 to 1:80, from 45:1 to 1:75, from 45:1 to 1:70, from 45:1 to 1:65, 45:1 to 1:60, 45:1 to 1:55 from 45:1 to 1:50, 45:1 to 1:40, 45:1 to 1:35, from 45:1 to 1:30, from 45:1 to 1:25, 45:1 to 1:20, 45:1 to 1:15, 45:1 to 1:10, from 5:1 to 1:5, from 45:1 to 1:4, 45:1 to 1:3, 45:1 to 1:2, 40:1 to 1:40, from 40:1 to 1:95, from 40:1 to 1:90, from 40:1 to 1:85, from 40:1 to 1:80, 40:1 to 1:75, 40:1 to 1:70, 40:1 to 1:65, from 40:1 to 1:60, from 40:1 to 1:55 from 40:1 to 1:50, from 40:1 to 1:45, from 40:1 to 1:35, from 40:1 to 1:30 PM, from 40:1 to 1:25, 40:1 to 1:20, from 40:1 to 1:15, 40:1 to 1:10, from 40:1 to 1:5, 40:1 to 1:4, 40:1 to 1:3, 40:1 to 1:2, 35:1 to 1:35, from 35:1 to 1:95, from 35:1 to 1:90, from 35:1 to 1:85, from 35:1 to 1:80, 35:1 to 1:75, 35:1 to 1:70, 35:1 to 1:65, 35:1 to 1:60, 35:1 to 1:55 from 35:1 to 1:50, from 35:1 to 1:45, from 35:1 to 1:40, from 35:1 to 1:30, 35:1 to 1:25, 35:1 to 1:20, 35:1 to 1:15, 35:1 to 1:10, 35:1 to 1:5, 35:1 to 1:4, 35:1 to 1:3, 35:1 to 1:2, 30:1 to 1:30, from 30:1 to 1:95, from 30:1 to 1:90, 30:1 to 1:85, from 30:1 to 1:80, 30:1 to 1:75, 30:1 to 1:70, from 30:1 to 1:65, 30:1 to 1:60, from 30:1 to 1:55, from 30:1 to 1:50, from 30:1 to 1:45, from 30:1 to 1:40, from 30:1 to 1:35, from 30:1 to 1:25, from 30:1 to 1:20, from 30:1 to 1:15, from 30:1 to 1:10, from 30:1 to 1:5, from 30:1 to 1:4, from 30:1 to 1:3, from 30:1 to 1:2, 25:1 to 1:25, from 25:1 to 1:95, from 25:1 to 1:90, 25:1 to 1:85, 25:1 to 1:80, 25:1 to 1:75, from 25:1 to 1:70, 25:1 to 1:65, from 25:1 to 1:60, from 25:1 to 1:55, from 25:1 to 1:50 25:1 to 1:45, from 25:1 to 1:40, from 25:1 to 1:35, from 25:1 to 1:30, from 25:1 to 1:20, from 25:1 to 1:15, 25:1 to 1:10, from 25:1 to 1:5, 25:1 to 1:4 from 25:1 to 1:3, 25:1 to 1:2, from 20:1 to 1:95, from 20:1 to 1:90, 20:1 to 1:85, from 20:1 to 1:80, from 20:1 to 1:75, from 20:1 to 1:70, from 20:1 to 1:65, from 20:1 to 1:60, from 20:1 to 1:55, from 20:1 to 1:50, from 20:1 to 1:45, from 20:1 to 1:40, from 20:1 to 1:35, from 20:1 to 1:30, from 20:1 to 1:25, from 20:1 to 1:15, from 20:1 to 1:10, from 20:1 to 1:5, from 20:1 to 1:4, from 20:1 to 1:3, from 20:1 to 1:2, 15:1 to 1:15, 15:1 to 1:95, from 15:1 to 1:90, 15: 1:85, from 15:1 to 1:80, from 15:1 to 1:75, from 15:1 to 1:70, from 15:1 to 1:65, from 15:1 to 1:60, from 15:1 to 1:55, from 15:1 to 1:50, from 15:1 to 1:45, from 15:1 to 1:40, from 15:1 to 1:35, from 15:1 to 1:30, from 15:1 to 1:25, from 15:1 to 1:20, from 15:1 to 1:10, from 15:1 to 1:5, from 15:1 to 1:4, from 15:1 to 1:3, from 15:1 to 1:2, from 10:1 to 1:10, from 10:1 to 1:95, from 10:1 to 1:90, from 10:1 to 1:85, 10:1 to 1:80, from 10:1 to 1:75, from 10:1 to 1:70, from 10:1 to 1:65, from 10:1 to 1:60, from 10:1 to 1:55, from 10:1 to 1:50, from 10:1 to 1:45, from 10:1 to 1:40, from 10:1 to 1:35, from 10:1 to 1:30, from 10:1 to 1:25, from 10:1 to 1:20, from 10:1 to 1:15, from 10:1 to 1:5, from 10:1 to 1:4, from 10:1 to 1:3, from 10:1 to 1:2, from 5:1 to 1:5, from 5:1 to 1:95, from 5:1 to 1:90, from 5:1 to 1:85, 5:1 to 1:80, from 5:1 to 1:75, from 5:1 to 1:70, from 5:1 to 1:65, from 5:1 to 1:60, from 5:1 to 1:55, 5:1 to 1:50, from 5:1 to 1:45, from 5:1 to 1:40, from 5:1 to 1:35, from 5:1 to 1:30, from 5:1 to 1:25, from 5:1 to 1:20, from 5:1 to 1:15, from 5:1 to 1:10, from 5:1 to 1:4, from 5:1 to 1:3, from 5:1 to 1:2, from 4:1 to 1:4, from 4:1 to 1:95, from 4:1 to 1:90, from 4:1 to 1:85, from 4:1 to 1:80, from 4:1 to 1:75, from 4:1 to 1:70, from 4:1 to 1:65, from 4:1 to 1:60, from 4:1 to 1:55, 4:1 to 1:50, from 4:1 to 1:45, 4:1 to 1:40, 4:1 to 1:35, from 4:1 to 1:30, from 4:1 to 1:25, from 4:1 to 1:20, from 4:1 to 1:15, from 4:1 to 1:10, from 4:1 to 1: 5, from 4:1 to 1:3, from 4:1 to 1:2, from 3:1 to 1:3, from 3:1 to 1:95, from 3:1 to 1:90, from 3:1 to 1:85, from 3:1 to 1:80 from 3:1 to 1:75, from 3:1 to 1:70, from 3:1 to 1:65, from 3:1 to 1:60, from 3:1 to 1:55, 3:1 to 1:50, 3:1 to 1:45, from 3:1 to 1:40, from 3:1 to 1:35, from 3:1 to 1:30, from 3:1 to 1:25, from 3:1 to 1:20, from 3:1 to 1:15, from 3:1 to 1:10, from 3:1 to 1: 5, from 3:1 to 1:4, from 3:1 to 1:2, 2:1 to 1:2, 2:1 to 1:95, 2:1 to 1:90, 2:1 to 1:85, 2:1 to 1:80, 2:1 to 1:75, 2:1 to 1:70, 2:1 to 1:65, 2:1 to 1:60, 2:1 to 1:55, 2:1 to 1:50, 2:1 to 1:45, 2:1 to 1:40,2:1 to 1:35, from 2:1 to 1:30, 2:1 to 1:25, from 2:1 to 1:20, from 2:1 to 1:15, from 2:1 to 1:10, from 2:1 to 1: 5, from 2:1 to 1:4, 2:1 to 1:3.

The compounds of formula (I) or active substances from the class of macrolides, carboxylates or other classes that contain at least one with the main character of the centre, for example, can form salts, for example, with strong inorganic acids, in particular mineral acids, for example, perarnau, sulfuric, hydrochloric, nitric, phosphoric or halogen acid, with strong organic carboxylic acids, such as unsubstituted or substituted, for example substituted by halogen alcancarao acids with 1-4 carbon atoms, in particular acetic acid, saturated or unsaturated dicarboxylic acids, for example, oxalic, malonic, succinic, maleic, fumaric or phthalic acid, with hydroxycarbonate acids, e.g. ascorbic, lactic, malic, tartaric or citric acid, benzoic acid, or organic sulphonic acids, such as unsubstituted or substituted, for example substituted by halogen of alkanesulfonyl or arylsulfonate with 1-4 carbon atoms, in particular, with methanesulphonate or p-toluensulfonate. The compounds of formula (I) or active substances from the class of macrolides, carboxylates or other classes, containing, IU the greater extent, one acid group, for example, can form salts with bases, e.g. metal salts, such as alkali or alkaline earth metals, in particular sodium, potassium or magnesium, salts with ammonia, an organic amine, such as morpholine, piperidine, pyrrolidine, lower monoalkylamines, dialkylamines or trialkylamines, in particular, ethylamine, diethylamine, triethylamine or dimethylpropylene, or lower monohydroxylation, dihydroxyaluminum or trihydroxystilbene, in particular, monoethanolamine, diethanolamine or triethanolamine. Along with this, under certain conditions, the formation of the corresponding internal salts. In accordance with the invention are preferred agrokhimichesky preferred salt. Given the close relationship between the free compounds of formula (I) or active substances from the class of macrolides, carboxylates or other classes and their salts, any of the above and subsequent description mentions of free compounds of formula (I) or free active substances from the class of macrolides, carboxylates or other classes or their salts should be understood (if it is relevant and appropriate) so that we are talking about the appropriate salts, respectively, the free compounds of formula (I) or free active substances and the class of macrolides, carboxylates or other classes. This applies to tautomers of compounds of formula (I), respectively, of active substances from the class of macrolides, carboxylates or other classes, as well as to the salts of the tautomers.

In accordance with the present invention the concept of "combination of active ingredients" used to refer to various combinations of compounds of formula I with active ingredients from the class of macrolides, carboxylates or other classes, for example, in the form of individual ready-mix or intended for spraying the combined mixture of individual products individual active substances prepared, for example, in the tank, and also to denote the combined used of the individual active substances if consistently applied, for example, within a reasonable short period of time, for example, within a few hours or days. In accordance with a preferred sequence of application of the compounds of formula (I) and active substances from the class of macrolides, carboxylates or other classes is not decisive for the implementation of the present invention.

Using the proposed invention in combinations of active substances as insecticides and acaricides consumption rates depending on the nature of the EPA application can vary within wide limits. When processing parts of plants, such as leaves, the rate of flow proposed in the invention combinations of active substances ranging from 0.1 to 10,000 g/ha, preferably from 10 to 1000 g/ha, particularly preferably from 50 to 300 g/ha (in case of use of the combinations specified by sprinkling or drip irrigation may reduce consumption norms, which primarily refers to the use of inert substrates like Rockwool or perlite), while in the processing of seed materials, it is from 2 to 200 g per 100 kg of seed, preferably from 3 to 150 g per 100 kg of seed, particularly preferably from 2.5 to 25 g per 100 kg of seed, more preferably from 2.5 to 12.5 g per 100 kg seed, and soil from 0.1 to 10,000 g/ha, preferably from 1 to 5000 g/ha

Used in accordance with the present invention norms of consumption are not limited to the above intervals should be considered as examples.

Proposed in the invention combination of active substances can be used to protect plants from damage above noxious animals, which remain unchanged over a certain period of time after the processing plants. The corresponding time period in the range from 1 to 28 days, prepact the tion from 1 to 14 days, particularly preferably from 1 to 10 days and even more preferably from 1 to 7 days in the case of treatment of active substances and plant reaches 200 days in the case of treatment of their seed.

Proposed in the invention combination of active substances, having good compatibility with plants, low toxicity when exposed to warm-blooded animals and high compatibility with the environment, are suitable for protecting plants and plant organs, for increasing the yield and improving the quality of the harvested crop, and also for control of noxious animals, especially insects, arachnids, helminths, nematodes and molluscs, which are encountered in agriculture, horticulture, animal husbandry, forests, in gardens and leisure facilities, in the protection of food supplies and materials and in the hygiene field. Proposed in the invention combination of active substances mainly can be used as plant protection products. They are effective in dealing with harmful animals having normal sensitivity, and appropriate sustainable views on all or individual stages of their development. The latter include pests of the following types.

Corps representatives lice (Phthiraptera), for example, Damalinia spp., Haematopinus spp., Linognathus spp.,Pediculus spp., Trichodectes spp.

Representatives of the class Arachnida, for example, Acarus siro, Aceria sheldoni, Aculops spp., Aculus spp., Amblyomma spp., Argas spp., Boophilus spp., Brevipalpus spp., Bryobia praetiosa, Chorioptes spp., Dermanyssus gallinae, Eotetranychus spp., Epitrimerus pyri, Eutetranychus spp., Eriophyes spp., Hemitarsonemus spp., Hyalomma spp., Ixodes spp., Latrodectus mactans, Metatetranychus spp., Oligonychus spp., Omithodoros spp., Panonychus spp., Phyllocoptruta oleivora, Polyphagotarsonemus latus, Psoroptes spp., Rhipicephalus spp., Rhizoglyphus spp., Sarcoptes spp., Scorpio maurus, Stenotarsonemus spp., Tarsonemus spp., Tetranychus spp., Vasates lycopersici.

Representatives of the class of bivalves, for example, Dreissena spp.

The representatives of the order of Gubanova, for example, Geophilus spp., Scutigera spp.

The representatives of the order Coleoptera, for example, Acanthoscelides obtectus, Adoretus spp., Agelastica aini, Aghotes spp., Amphimallon solstitialis, Anobium punctatum, Anoplophora spp., Anthonomus spp., Anthrenus spp., Apogonia spp., Atomaria spp., Attagenus spp., Bruchidius obtectus, Bruchus spp., Ceuthorhynchus spp., Cleonus mendicus, Conoderus spp., Cosmopolites spp., Costelytra zealandica, Curculio spp., Cryptorhynchus lapathi, Dermestes spp., Diabrotica spp., Epilachna spp., Faustinus cubae, Gibbium psylloides, Heteronychus arator, Hylamorpha elegans, Hylotrupes bajulus, Hypera postica, Hypothenemus spp., Lachnosterna consanguinea, Leptinotarsa decemlineata, Lissorhoptrus oryzophilus, Lixus spp., Lyctus spp., Meligethes aeneus, Melolontha melolontha, Migdolus spp., Monochamus spp., Naupactus xanthographus, Niptus hololeucus, Oryctes rhinoceros, Oryzaephilus surinamensis, Otiorrhynchus culcatus, Oxycetonia jucunda, Phaedon cochleariae, Phyllophaga spp., Popillia japonica, Premnotrypes spp., Psylliodes chrysocephala, Ptinus spp., Rhizobius ventralis, Rhizopertha dominica, Sitophilus spp., Sphenophorus spp., Stemechus spp., Symphyletes spp., Teneblio molitor, Tribolium spp., Trogoderma spp., Tychius spp., Xylotrechus spp., Zabrus spp.

The representatives of the order of the Collembola, for example Onychiurus armatus.

the representatives of the order historylink insects, for example, Forficula auricularia.

Representatives of the troop diplopod, for example, Blaniulus guttulamus.

The representatives of the order Diptera, for example Aedes spp., Anopheles spp., Bibio hortulanus, Calliphora erythrocephala, Ceratitis capitata, Chrysomyia spp., Cochliomyia spp., Cordylobia anthropophaga, Culex spp., Cuterebra spp., Dacus oleae, Dermatobia hominis, Drosophila spp., Fannia spp., Gastrophilus spp., Hylemyia spp., Hyppobosca spp., Hypoderma spp., Liriomyza spp.Lucilia spp., Musca spp., Nezara spp., Oestrus spp., Oscinella frit, Pegomyia hyoscyami, Phorbia spp., Stomoxys spp., Tabanus spp., Tannia spp., Tipula paludosa, Wohlfahrtia spp.

Representatives of the class of gastropods, for example, Anon spp., Biomphalaria spp., Bulinus spp., Deroceras spp., Galba spp., Lymnaea spp., Oncomelania spp., Succinea spp.

Representatives of the class of helminths, for example, Ancylostoma duodenale, Ancylostoma ceylanicum, Acylostoma braziliensis, Ancylostoma spp., Ascaris lubricoides, Ascaris spp., Brugia malayi, Brugia timori, Bunostomum spp., Chabertia spp., Clonorchis spp., Coopena spp., Dicrocoelium spp, Dictyocaulus filana, Diphyllobothrium latum, Dracunculus medinensis, Echinococcus granulosus, Echinococcus multilocularis, Enterobius vermicularis, Faciola spp., At spp., Heterakis spp., Hymenolepis dad, Hyostrongulus spp., Loa Loa, Nematodirus spp., The recommended dose rate spp., Opisthorchis spp., Onchocerca volvulus, Ostertagia spp., Paragonimus spp., Schistosomen spp, Strongyloides fuellebomi, Strongyloides stercoralis, Stronyloides spp., Taenia saginata, Taenia solium, Trichinella spiralis, Tiichinella nativa, Trichinella britovi, Trichinella nelsoni, Trichinella pseudopsiralis, Trichostrongulus spp., Trichuhs trichuria, Wuchereria bancrofti.

Protozoa, in particular, Eimeria.

The representatives of the order Hemiptera insects, for example, Anasa tristis, Antestiopsis spp., Blissus spp., Calocoris spp., Campylomma livida, Cavelerius spp., Cimex spp., Creontiades dilutus, Dasynus piperis, Dichelops furcatus, Diconocons hewetti, Dysdercus spp., Euschistus spp., Eurygaster sp., Heliopeltis spp., Horcias nobilellus, Leptocorisa spp., Leptoglossus phyllopus, Lygus spp., Macropes excavatus, Miridae, Nezara spp., Oebalus spp., Pentomidae, Piesma quadrata, Piezodorus spp., Psallus seiiatus, Pseudacysta persea, Rhodnius spp., Sahlbergella singularis, Scotinophora spp., Stephanitis nashi, Tibraca spp., Triatoma spp.

Corps representatives ranarridh Robotnik insects, for example, Acyrthosipon spp., Aeneolamia spp., Agonoscena spp., Aleurodes spp., Aleurolobus barodensis, Aleurothhxus spp., Amrasca spp., Anuraphis cardui, Aonidiella spp., Aphanostigma pin, Aphis spp., Arboridia apicalis, Aspidiella spp., Aspidiotus spp., Atarius spp., Aulacorthum solani, Bemisia spp., Brachycaudus helichrysii, Brachycolus spp., Brevicoryne brassicae, Calligypona marginata, Cameocephala fulgida, Ceratovacuna lanigera, Cercopidae, Ceroplastes spp., Chaetosiphon fragaefolii, Chionaspis tegalensis, Chlorita onukii, Chromaphis juglandicola, Chrysomphalus ficus, Cicadulina mbila, Coccomytilus halli, Coccus spp., Cryptomyzus ribis, Dalbulus spp. Dialeurodes spp., Diaphorina spp., Diaspis spp., Doralis spp., Drosicha spp., Dysaphis spp., Dysmicoccus spp., Empoasca spp., Eriosoma spp., Erythroneura spp., Euscelis bilobatus, Geococcus coffeae, Homalodisca coagulate, Hyalopterus arundinis, a leery spp., Idiocerus spp., Idioscopus spp., Laodelphax stiiatellus, Lecanium spp., Lepidosaphes spp., Lipaphis erysimi, Macrosiphum spp., Mahanarva fimbnolata, Melanaphis sacchari, Metcalfiella spp., Metopolophium dirhodum, Monellia costalis, Monelliopsis pecanis, Myzus spp., Nasonovia ribisnigri, Nephotettix spp., Nilaparvata lugens, Oncometopia spp., Orthezia praelonga, Parabemisia myricae, Paratrioza spp., Parlatoria spp., Pemphigus spp., Peregrin us that id is, Phenacoccus spp., Phloeomyzus passerinii, Phorodon humuli, Phylloxera spp., Pinnaspis aspidistrae, Planococcus spp., Protopulvinaria pyriformis, Pseudaulacaspis pentagona, Pseudococcus spp., Psylla spp., Pteromalus spp., Pyrilla spp., Quadraspidiotus spp., Quesada gigas, Rastrococcus spp., Rhopalosiphum spp., Saissetia spp., Scaphoides titanus, Schizaphis graminum, Selenaspidus articulatus, Sogata spp., Sogatella furcifera, Sogatodes spp., Stictocephala festina, Tenalaphara malayensis, Tinocallis caryaefoliae, Tomaspis spp., Toxoptera spp., Trialeurodes vaprariorum, Trioza spp., Typhlocyba spp., Unaspis spp., Viteus vitifolii.

The representatives of the order Hymenoptera insects, for example, Diprion spp., Hoplocampa spp., Lasius spp., Monomorium pharaonis, Vespa spp.

The representatives of the order of isopod crustaceans, for example, Armadillidium vulgare, Oniscus asellus, Porcellio scaber.

The representatives of the order of the white ants, for example, Reticulitermes spp., Odontotermes spp.

The representatives of the order Lepidoptera, for example, Acronicta major, Aedia leucomelas, Agrotis spp., Alabama argillacea, Anticarsia spp., Barathra brassicae, Bucculatrix thurberiella, Bupalus piniarius, Cacoecia podana, Capua retisilana, Carpocapsa pomonella, Cheimatobia brumata, Chilo spp., Chohstoneura fumiferana, Clysia ambiguella, Cnaphalocerus spp., Earias insilana, Ephestia kuehniella, Euproctis chrysorrhoea, Euxoa spp., Feltia spp., Galleria mellonella, Helicoverpa spp., Heliothis spp., Hofmannophila pseudospretella, Homona magnanima, Hyponomeuta padella, Laphygma spp., Lithocolletis blancardella, Lithophane antennata, Loxagrotis albicosta, Lymantria spp., Malacosoma neustria, Mamestra brassicae, Mods repanda, Mythimna separata, Oria spp., Oulema oryzae, Panolis flammea, Pectinophora gossypiella, Phyllocnistis citrella, Pieris spp., Plutella xylostella, Prodenia spp., Pseudaletia spp., Pseudoplusia includens, Pyrausta nubilalis, Spodoptera spp., Thermesia gemmatalis, Tinea pellionella, Tineola bisselliella, Torthx viridana, Trichoplusia spp.

Representatives of group hopping orthopterous insects, for example, Acheta domesticus, Blatta orientalis, Blattella germanica, Gryllotalpa spp., Leucophaea maderae, Locusta spp., Melanoplus spp., Periplaneta americana, Schistocerca gregaria.

The representatives of the order of fleas, for example, Ceratophyllus spp., Xenopsylla cheopis.

The representatives of the order of simpily, for example, Scutigerella immaculata.

Corps representatives bajracharya insects, for example, Baliothrips biformis, Enneothrips flavens, Frankliniella spp., Helithrips spp., Hercinothrips femoralis, Kakothrips spp., Rhipiphorothrips cruentatus, Scirtothrips spp., Taeniothhps cardamoni, Thrips spp.

Corps representatives stinkwood, for example, Lepisma saccharina.

Parasitic plant nematodes, e.g., Anguina spp., Aphelenchoides spp., Belonoaimus spp., Bursaphelenchus spp., Ditylenchus dipsaci, Globodera spp., Heliocotylenchus spp., Heterodera spp., Longidorus spp., Meloidogyne spp., Pratylenchus spp., Radopholus similis, Rotylenchus spp., Trichodorus spp., Tyienchorhynchus spp., Tyienchulus spp., Tyienchulus semipenetrans, Xiphinema spp.

Proposed in the invention combination of active substances in certain concentrations, respectively, at certain application rates, if necessary, can also be used as herbicides, protective measures, plant growth regulators, or tools to improve their properties, as well as microbicides, for example, fungicides, fungicides, bactericides, viricides (including remedies against viroids) or anti-mycoplasmology and similar to Rickettsia organisms.

The active substances can be in the form of conventional preparations such as solutions, emulsions, wettable powders, suspensions, water-or oil-based, powders, powdered drugs, pastes, soluble powders, soluble granules, sprinkle the granules, suspension-emulsion concentrates, impregnated with active ingredient of natural materials impregnated with active compound, synthetic substances is a, fertilizers and finely dispersed capsules with a shell of polymeric materials.

These drugs can be produced with known methods, e.g. by mixing the active substances with a neutral fillers, that is liquid solvents and/or solid carriers, optionally with the use of surfactants, that is emulsifiers, dispersants and/or foam-forming agents. Preparations are made at the appropriate settings, as well as before or in the process of their application.

As auxiliary substances can be used substances which can give itself the means and/or made of these drugs (for example, working solutions or remedies for seed) special properties, for example, certain technical and/or specific biological properties. Typical tools are neutral fillers, solvents and carriers.

Suitable neutral fillers are, for example, water, polar and nonpolar organic chemical fluid relating to, for example, to the classes of aromatic or non-aromatic hydrocarbons (such as paraffins, alkyl benzenes, alkylnaphthalene or chlorobenzene), alcohols and polyols (which in some cases may also be substituted or converted the simple and/or esters), ketones (such as acetone or cyclohexanone), esters (including fats and oils), polyether, primary and substituted amines, amides, lactams (such as M-alkylpyridine) and lactones, sulfones and sulfoxidov (such as dimethylsulfoxide).

In the case of using water as a neutral filler as an auxiliary solvent can also be used, for example, organic solvents. Suitable liquid solvents are aromatic hydrocarbons, such as xylene, toluene or alkylnaphthalenes, chlorinated aromatics and chlorinated aliphatic hydrocarbons, such as chlorobenzene, chloroethylene or methylene chloride, aliphatic hydrocarbons, such as cyclohexane or paraffins, for example petroleum fractions, mineral and vegetable oils, alcohols, such as butanol or glycol and also their ethers and esters, ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, strongly polar solvents, such candeleteselection, as well as water.

According to the invention the carrier is a natural or synthetic, organic or inorganic substance which can be in solid or liquid state and which active substances are mixed or combined to best note is namesti, primarily for application to plants or plant parts or seed. Solid or liquid media in General is an inert material acceptable for use in agricultural practice.

Suitable solid carriers are, for example, the following materials.

Ammonium salts; natural mineral powders, in particular, kaolin, alumina, talc, chalk, quartz, attapulgite, montmorillonite and diatomaceous earth; synthetic mineral powders, in particular, highly dispersed silicic acid, alumina and silicates; suitable solid carriers in the case of granules are, for example, crushed and fractionated rocks, such as calcite, marble, pumice, thick or dolomite, and synthetic granules of inorganic and organic powders, and granules of organic materials such as paper, sawdust, coconut shell, corn cobs and tobacco stalks; suitable emulsifying and/or foam-forming agents are, for example, nonionic and anionic emulsifiers, in particular, complex polyoxyethylene esters of fatty acids, simple polyoxyethylene esters of aliphatic alcohols, for example, alkylresorcinol, as well as alkyl sulphonates, alkyl sulphates, arylsulfonate and protein hydrolysates; suitable dispersant and are nonionic and/or ionic substances, for example, representatives of the class of simple polyoxyethylenated and/or polyoxypropylene esters of alcohols, complex polyoxypropylene and/or polyoxyethylenated esters of acids, simple alkylaryl and/or polyoxypropylene and polyoxyethylene esters of adducts of fats and/or polyoxypropylene and polyoxyethylene derivatives, polyhydric polyoxyethylenated and/or polyoxypropylene alcohols, adducts of polyoxyethylene and/or polyoxypropylene and sorbitol or Sugars, alkyl sulphates, arylsulfatase, sulfonates and phosphates or the corresponding esters of adducts of propylene oxide. Suitable are also oligomers or polymers, for example, vinyl monomers, acrylic acid, ethylene oxide and/or propylene oxide or ethylene oxide and/or propylene oxide in combination with, for example, (poly)alcohols or (poly)amines. In addition, you can use lignin and its sulfonylurea derivative, conventional and modified cellulose, aromatic and/or aliphatic sulfonic acids, and their adducts with formaldehyde.

The drugs can be used as adhesion promoters, in particular, carboxymethyl cellulose, natural or synthetic, powder, granular or in the form of latex polymers, such as gum Arabic, polyvinyl alcohol and polyvinyl acetate, and also natural, such as the KEF the ins and lecithins, and synthetic phospholipids.

In addition, you can use the dyes, in particular, inorganic pigments, for example iron oxide, titanium oxide or Prussian blue, and organic dyes, in particular, alizarin dyes, azo dyes and metallophthalocyanine dyes, and trace elements such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc.

As additional additives can be used fragrances, mineral or vegetable, optionally modified oils, waxes and nutrients (including trace elements), such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc.

In addition, the preparations can contain stabilizers, in particular, protection from freezing, preservatives, antioxidants, light stabilizers or other means to improve chemical and/or physical stability.

The content of active substances in products derived from trading drugs work forms can be varied within wide limits.

The concentration of the active substance in the working form is in the range from 0,00000001 to 97 wt. -%, preferably from 0.0000001 to 97 wt. -%, particularly preferably from 0.000001 to 83% of the mass. or from 0.000001 to 5% by mass. and even more preferably from 0.0001 to 1% of the mass.

Proposed in the invention combined the promotion of active substances can be in the form of the relevant trading drugs as well as business forms, produced by mixing these drugs with other active substances, such as insecticides, attractants, sterilizing agents, bactericides, acaricides, nematicides, fungicides, substances for regulating the growth of plants, herbicides, protective equipment, fertilizers or signaling substances.

In addition, the proposed in the invention combination of active substances can be mixed with other known active substances, such as herbicides, fertilizers, growth regulators, protective equipment or signaling substances, or with means to improve properties of plants.

Along with this, when using the proposed invention combinations of active substances as insecticides, they may be in the respective trading agents, as well as produced from these drugs work forms in a mixture with synergists. The synergists are compounds, adding which helps to enhance the efficacy of active substances, and he added synergist should not have activity.

Proposed in the invention combination of active ingredients when used as insecticides may be relevant trading agents, as well as produced from these drugs work forms in a mixture with Inga is itonami, to reduce degradation of the active substance after its application in the external environment of the plant, on the surface of parts of plants or in plant tissues.

The use of combinations of active substances carried out by usual method, which corresponds to the working form.

According to the invention the processing can be subjected to all plants or plant parts. Under the plants imply any species and populations such as desired and undesired wild or cultivated plants (including that occurring under natural conditions plants). Moreover, under cultivated plants include plants that can be grown by conventional methods of breeding and optimization methods of biotechnology and gene technology, or by combining these methods, including the transgenic plants and plant varieties which are protected or not protected varietal certificates. Under parts of plants imply any above-ground and below-ground parts and organs of plants, such as shoots, leaves, flowers and roots, and are preferred leaves, needles, stems, trunks, flowers, perianth, fruits and seeds and also roots, tubers and rhizomes. The plant parts also include harvested and intended for reproduction vegetative and generative material, for example, fruits, seeds, che is Enki, tubers, rhizomes, cuttings, seeds, bulbs, arcuate cuttings and root suckers.

According to the invention the treatment of the plants and parts of plants combinations of active substances is carried out directly or by action on their surrounding area, habitat or private store, using conventional methods, for example, dipping, spraying, evaporation, thin spraying, spreading, smearing, injection, while the processing used for propagation material, especially seeds, are also carried out by single or multiple wraps.

The plants according to the invention can be processed include cotton, flax, grapes, fruit trees, vegetables, such as Rosaceae sp. (for example, pome fruit trees such as apples and pears, stone fruit trees such as apricots, cherries, almonds and peaches, as well as garden and berry crops, such as strawberries), Ribesioidae sp., Juglandaceae sp., A sp., Anacardiaceae sp., Fagaceae sp., Moraceae sp., Oleaceae sp., Actinidaceae sp., Lauraceae sp., Musaceae sp.(for example, banana trees and banana plantations), Rubiaceae sp.(for example coffee), Theaceae sp., Sterculiceae sp., Rutaceae sp. (for example, lemons, oranges and grapefruit); Solanaceae sp. (for example tomatoes), Liliaceae sp., Asteraceae sp. (for example lettuce), Umbelliferae sp., Cruciferae sp., Chenopodiaceae sp., Cucurbitaceae sp.(for example cucumbers), Aliaceae sp. (for example, garlic, onions), Papilionaceae sp. (for example peas); major useful plants such as Gramineae sp. (for example maize, turf, cereals such as wheat, rye, rice, barley, oats, millet and triticale), Asteraceae sp. (for example sunflower), Brassicaceae sp. (for example white cabbage, red cabbage, broccoli, cauliflower, Brussels sprouts, Chinese cabbage, kohlrabi, radish, and canola, mustard, sea cabbage and cress salad), Fabacae sp. (for example beans, peanuts), Papilionaceae sp. (for example soya beans), Solanaceae sp.(for example potatoes), Chenopodiaceae sp. (for example, sugar beet, fodder beet, chard, red vegetable beet); grown in gardens and forests of useful and ornamental plants, and genetically modified types of these plants.

Proposed in the invention combination of active substances is primarily suitable for the treatment of seed materials. While preferred are the above preferred or particularly preferred proposed in the invention combination of active substances. It is known that pests cause damage to cultivated plants are now mostly because of the infestation of seed during storage and after incorporation into the soil, as well as during germination of plants and directly after ushodaya phase is especially critical, since the roots and shoots of the growing plant have a special sensitivity, and even minor damage can lead to death of the whole plant. In this regard, of great practical interest is the protection of seed materials and growing of these plants provided through the use of suitable tools.

Implemented by appropriate treatment, protection of seed materials from pests has long been known and is continuously improved. However, when such processing, there are several problems, which is not always possible to solve in a satisfactory manner. Thus, of particular interest is the development of a method of protecting seed materials and growing of these plants, which would waive the need for additional application of crop protection products after planting or after emergence. Also of great interest is the optimization of the quantity of the active substance, to better protect the seed and the germinating from it the plant from damage by pests and to avoid damage to the plants used by the active substance. For optimum protection of the seed material, as well as growing of these plants with a minimum expenditure of means of protection of plants the processing methods seed materials should also be considered inherent in the use of transgenic plants with insecticidal properties.

With regard to the foregoing, the present invention relates also to a method for protection of seed materials and growing of these plants from damage by pests, in accordance with which the seed material is subjected to processing proposed in the invention combination of active substances. Proposed in the invention is a method for protection of seed materials and growing of these plants from damage by pests involves simultaneous processing of seed active ingredient of formula (I) and one of the active ingredients of the above groups. The method also includes processing the seed active ingredient of formula (I) and one of the active ingredients of the above groups, respectively, carried out in different moments of time. The invention relates also to the use intended for the treatment of seed materials proposed in the invention combinations of active substances for the protection of seed materials and growing of these plants from pests. In addition, the invention relates to seed material, which is to protect from pests subjected to the treatment proposed in the invention combination of active substances. The invention relates also to seed material, which simultaneously process the active substance of the formula (I) and one of the active ingredients of the above groups. In addition, the invention relates to seed material, which is treated with the active substance of the formula (I) and one of the active ingredients of the above groups, respectively, at different points in time. Individual active substances proposed in the invention means may be present in different layers of seed materials, which process the active substance of the formula (I) odnim of the active ingredients of the above groups at different points in time. While the layers containing the active substance of the formula (I) and one of the active ingredients of the above groups may optionally be separated from each other by an intermediate layer. In addition, the invention relates to seed material from which the active substance of the formula (I) and one of the active ingredients of the above groups plotted as a shell component, or as a further layer or further layers in addition to the shell.

One of the advantages of the present invention is that due to the special system properties proposed in the invention combinations of active substances treatment of seed material such combinations of active ingredients provides protection from pests not only the seed, but the sprouting of plants after construction is their shoots. This does away with the need for immediate processing of the culture at the time of planting or after a short period of time after sowing.

Another advantage of the invention consists in energiticheskom increase the insecticidal effectiveness of the proposed invention in combinations of active substances, which exceeds the amount of insecticidal efficacies of two active substances at their separate application. An advantage of the invention is also a synergistic increase in the fungicidal effectiveness of the proposed invention in combinations of active substances, which exceeds the amount of antifungal efficacies of two active substances at their separate application. This makes it possible to optimize the number of active substances.

Moreover, an advantage of the present invention is the ability of the proposed use in the invention combinations of active substances for the treatment of transgenic seed materials, and plants growing from processed similarly seed materials capable of experimenatl pests affecting protein. Thus, treatment of seed materials proposed in the invention combinations of active substances allows you to control certain pests thanks to Express the AI, for example, insecticidal protein, i.e. in addition to the direct protection of plants from pests proposed in the invention combinations of active substances.

Proposed in the invention combination of active substances suitable for protecting seed of the plant of any of the above species used in agriculture, greenhouses, forests or in horticulture. It is primarily about the seed materials of maize, peanut, canola, rapeseed, poppy seed, soybean, cotton, beet (for example sugar or fodder), rice, millet, wheat, barley, oats, rye, sunflower, tobacco, potato, or vegetable plants such as tomatoes and cabbage). Proposed in the invention combination of active substances suitable for the treatment of seed material above the fruit and vegetable plants. Of particular importance is the treatment of seed corn, soybeans, cotton, wheat, canola and rapeseed.

As stated above, great importance is also the treatment proposed in the invention combinations of active substances transgenic seed materials. The concern of seed materials of plants containing typically at least one heterologous gene that regulates the expression of the polypeptide, especially with insecticidal properties. P and contained in this transgenic seed heterologous genes can originate from microorganisms, such as Bacillus, Rhizobium, Pseudomonas, Serratia, Trichoderma, Clavibacter, glomus or Gliocladium. The present invention is particularly suitable for the treatment of transgenic seed that contains at least one heterologous gene that comes from the bacilli, and the corresponding gene product has efficacy against corn Ognevka and/or corn temprado. It is especially preferably is about heterologous gene derived from Bacillus thuringiensis.

In accordance with the present invention proposed in the invention of the combination of active substances applied on the seed material as such or in the form of the corresponding drug. The treatment is preferably subjected to a seed, which is in a stable condition, which eliminates damage during processing. Processing of seed material in the General case can be done at any time between harvest and sowing. The treatment is usually subjected to a seed, which is separated from the plant or corn cob and released from the peel, stems, shells, woolly pubescence or fruit pulp.

The number applied to the seed material proposed in the invention combination of active substances and/or additional additives in the processing of seed materials in General should wybir the ü thus, not to have violated the germination of seeds and was not damaged sprouting from his plant. The specified condition must be observed primarily in the use of active substances which, under certain norms of consumption may have fitotoksicheskie action.

Proposed in the invention means can be applied to seed directly, i.e. without the use of additional components and without prior dilution. Generally preferred is the application of seed funds in the form of the corresponding drug. Suitable drugs and treatment methods seed materials known to the skilled specialists and described, for example, in U.S. patents US 4272417 A, US 4245432 A, US 4808430 A, US 5876739 and US 2003/0176428 A1, as well as in international applications WO 2002/080675 A1 and WO 2002/028186 A2.

Used according to the invention the active substances can be converted in the usual disinfectants preparations such as solutions, emulsions, suspensions, powders, foams, slurry or other enveloping seed mass, and also ULV drugs.

These drugs are made known methods by mixing the active substances with conventional additives, such as conventional neutral fillers, solvents, diluents, colorants, wetting agents, dispersing agents, alligatory, defoamers, preservatives, secondary thickeners, adhesives, gibberelin, as well as water.

Used according to the invention the preparations disinfectants as dyes may contain any commonly used for such purpose products. This can be used as a poorly water-soluble pigments, and water-soluble dyes. Relevant examples include dyes, also known as rhodamine B, C.I. pigment Red 112 and C.I. Solvent Red 1.

Used according to the invention the preparations disinfectants as wetting agents can include any promoting wetting substances, usually introduced in the formulations of agrochemical active substances. Thus preferably used alkylnaphthalene, in particular, populationcontrol or diisobutyldimethoxysilane.

Used according to the invention the preparations disinfectants as dispersants and/or emulsifiers can include any nonionic, anionic and cationic dispersing agents are usually introduced in the formulations of agrochemical active substances. Preferably used nonionic or anionic dispersing agents or a mixture of nonionic or anionic dispersants. Fit a nonionic dispersing agents are primarily block copolymers ethyl is noxide with propylene oxide, alkylpolyglycoside and muistiinpanosovelma and their phosphated or sulfated derivatives. Suitable anionic dispersing agents are primarily ligninsulfonate, salts of polyacrylic acid and condensation products arylsulfonate with formaldehyde.

Used according to the invention the preparations disinfectants as defoamers can contain any antifoaming substances usually introduced in the formulations of agrochemical active substances. While it is preferable to use silicone defoamers and magnesium stearate.

Used according to the invention the preparations disinfectants as preservatives may contain any suitable for canning agrochemical means substances. Examples of such substances are dichlorophen and preformal benzyl alcohol.

Used according to the invention the preparations disinfectants as secondary thickeners can include any suitable secondary thickening of the agrochemical means substances. Preferred agents of this type are derivatives of cellulose, derivatives of acrylic acid, xanthan gum, modified clays and highly dispersed silicic acid.

Used according to the invention the preparations disinfectants as adhesives can containing the ü any usually enter into the composition of disinfectants binders. Preferred adhesives are polyvinylpyrrolidone, polyvinyl acetate, polyvinyl alcohol, tylose.

Used according to the invention the preparations disinfectants as gibberellins preferably may contain gibberellin A1, A3 (gibberellinovuyu acid), A4 and A7, and particularly preferably used gibberellinovuyu acid. Gibberelin are known substances (see, for example, I.R. Wegler "Chemie der Pflanzenschutz - und Schädlingsbekämpfungsmittel", volume 2, Springer, 1970, cc.401-412).

According to the invention the preparations disinfectants can be used for processing of seed materials of different type, including seed material of transgenic plants, either directly or after prior dilution with water. In this case, thanks to their joint action resulting from the expression of substances can be achieved also additional synergistic effects.

For processing of seed materials used according to the invention the preparations of reagents or compositions derived from similar substances by adding water, you can use any mixing devices commonly used for seed. When this seed is loaded into the mixer, then add the required amount of fungicide fungicide (as t is the same or diluted with water), and these components are mixed until they reach a uniform distribution of the drug on the seed material. Then, if necessary, carry out the drying of seeds.

Proposed in the invention method can be used for handling genetically modified organisms, e.g. plants or seeds. Genetically modified (or transgenic) plants are called plant containing stably integrated into the genome of a heterologous gene. "Heterologous gene" mainly mean cooked or assembled outside the plant gene, which after the introduction into the genome of the cell nucleus, chloroplastic genome or hypochondriac genome of transgenic plants gives the latest new or improved agronomic or other properties due to the fact that he or exprimere a given protein or polypeptide, or violates a regulation or disables another gene, respectively other available plant genes (for example, through antisense technology, compressional technology or interference RNA). Present in the genome of a heterologous gene is also called a transgene. The transgene determined by its specific presence in the genome of the plant, called transformational, respectively transgenic object.

Depending the type or variety of plant, places of their growth, and growth conditions (soils, climate, vegetation period, diet) proposed in the invention, the processing may also lead to vergadain (synergistic) effects. So, for example, can be obtained the following effects beyond the originally expected: reduced rates of consumption, spread spectrum and/or improved efficiency used according to the invention of active substances and compositions, more intensive plant growth, increased tolerance of plants against high or low temperatures, increased tolerance of the plants to the aridity of the soil or to the increased content of water or salts, increased intensity of flowering and easier harvesting, accelerated maturation, higher yields, more intense fruiting, increase in plant height, more intense green color of the leaves, earlier flowering, higher quality and/or higher nutritional value of the harvested crop, a higher concentration of sugar in fruit, but also improved the suitability of the crop for storage and/or processing.

Proposed in the invention combination of active substances under specific consumption norms can have on plants is also a tonic effect. In this regard, they prigoda the s for the mobilization of plant defense system in the event of exposure of unwanted phytopathogenic fungi, microorganisms and/or viruses. It under certain conditions may be a cause of the increased effectiveness of the proposed invention in combinations of active substances, for example, increased antifungal effectiveness. In this regard, tonic plant substances (substances that induce plant resistance) must be also substance or combination of substances capable of stimulate defense system of plants so that plants treated by them, directly after the treatment inoculated with unwanted phytopathogenic fungi, microorganisms and/or viruses possessed a high resistance against such unwanted phytopathogenic fungi, microorganisms and/or viruses. Under unwanted phytopathogenic fungi, microorganisms and/or viruses in this case, the mean of phytopathogenic fungi, bacteria and viruses. Thus, the proposed invention substances should be used to protect plants from these pathogens, acting within a certain period of time after treatment. The period of time during which the protective action proposed in the invention of substances in the range of from 1 to 10 days, preferably from 1 to 7 days after treatment plants existing substances is mi.

Plants and plant varieties, preferably machined proposed in the invention method, includes any plants which have genetic material, give these plants are especially preferred useful properties (regardless of, provided the presence of such hereditary material by cultivation and/or biotechnology).

Plants and plant varieties, preferably machined proposed in the invention method, are resistant against one or more biotic factors of stress, that is, these plants have better protection from harmful animals and micro-organisms, such as nematodes, insects, mites, phytopathogenic fungi, bacteria, viruses and/or viroids.

Plants and plant varieties that can be subjected to processing proposed in the invention method, are plants that are resistant against one or more abiotic stress factors. Conditions for abiotic stress can be, for example, drought, cold and heat, osmotic permeability, stagnant excessive moisture, high salt content in the soil, elevated exposure to minerals, ozone, excessive light exposure, limited availability attester is asih nutrients, limited availability fosforsoderzhashhikh nutrients or the lack of shade.

Plants and plant varieties that can be subjected to processing proposed in the invention method include plants having increased yield. High productivity of such plants may be due to, for example, improved fitopatologia, improved plant growth and development, effective absorption and effective water retention, improved digestibility of nitrogen, intensive carbon assimilation, improved photosynthesis, intensive germination and accelerated maturation. Higher yields may be attributed to the improved architecture of the plant (under stress and in his absence), including early flowering, control of flowering to produce hybrid seed, bistarelli, size of plant, number of internodes and the distance between them, root growth, seed size, fruit size, sizes of pods, number of pods or ears, the number of seeds in pods or ears, weight of seeds, stronger seed filling, less intense shedding seeds, less intensive cracking seeds, as well as high resistance of plants to lodging. Other factors increased yields are the composition of the mJy (carb, proteins and oils, the composition of the oils, nutritional value, limiting the content of preventing the power connections, improved technological properties and improved suitability for storage.

Plants that can be subjected to processing proposed in the invention method are hybrid plants that already exprimitur signs of heterosis (hybrid effect), which in General leads to increased yield, increased bistarelli, improved health and increased resistance against biotic factors and abiotic stress. Such plants are typically created by crossing inbred Androsterone parental line (female partner for mating with another inbred introvertly parent line (the male partner, the crossing). Hybrid seed in the typical case removed separately from Androsterone plants and sell for breeding. Androsterone plants in some cases (for example, in the case of maize) can be produced by mechanical removal of the male reproductive organs, respectively, of male flowers, but androstadienone is usually caused by genetic determinants in the plant genome. In this case, especially if the target product includes seeds (if you intend to collect from Ojai hybrid plants), favorable is usually full recovery underfertilized in hybrid plants that contain responsible for androstadienone genetic determinants. Such recovery can be achieved due to the fact that the male partners of crossing possess adequate fertile vestigial organs that can restore underfertilized in hybrid plants containing responsible for androstadienone genetic determinants. Responsible for androstadienone genetic determinants can be localized in the cytoplasm. Examples of cytoplasmic androstadienone (CMS), for example, in the case of root vegetables of the genus Brassica described in international applications WO 1992/005251, WO 1995/009910, WO 1998/27806, WO 2005/002324 and WO 2006/021972, as well as in U.S. patent US 6229072. However, responsible for androstadienone genetic determinants can also be localized in the genome of the cell nucleus. Androsterone plants can also be created by methods of biotechnology, particularly genetic engineering. Particularly favorable tool for creating and endroster ilen plants described in international application WO 89/10396, and in the cells lining layer stamens will selectively exprimitur, for example, ribonuclease, in particular, barnase. Fertility in such case, you may be restoring the and by expression in the cells of the tapetum of the ribonuclease inhibitor, in particular, barstar (see, for example, international application WO 1991/002069).

Plants or parts of plants that can be created by methods of biotechnology, particularly genetic engineering, and which can be subjected to processing proposed in the invention method, have the tolerance to herbicides, there are plants engineered tolerance to one or more specified herbicides. Such plants can be obtained by genetic transformation or by selection of plants contain a mutation imparting tolerance to herbicides.

Tolerant to herbicides by plants are, for example, plants engineered tolerance to glyphosate or its salts. Tolerant towards glifosato plants can be created, for example, by transformation through gene, which encodes 5-enolpyruvylshikimate-3-fosfolinazou (EPSPS protein). Such EPSPS protein-genes, for example, refers AroA gene (mutant ST7) Salmonella typhimurium (Comai and others, Science (1983), 221, 370-371), the CP4 gene of the bacterium Agrobactehum sp.(Barry and others, Curr. Topics Plant Physiol. (1992), 7, 139-145), genes that encode EPSPS protein from Petunia (Shah and others, Science (1986), 233, 478-481, EPSPS protein from tomato (Gasser and others, J. Biol. Chem. (1988), 263, 4280-4289) or EPSPS protein from Degussa (international application WO 2001/66704). We can talk about mutated EPSS (see, for example, European patent application EP-A 0837944, as well as international application WO 2000/066746, WO 2000/066747 and WO 2002/026995). Tolerant towards glifosato plants can be created through the gene that encodes glyphosate-oxidoreductase (see, for example, U.S. patent US 5776 760 and US 5463 175). Tolerant towards glifosato plants can be created through the gene that encodes glyphosate-acetyltransferase (see, for example, international application WO 2002/036782, WO 2003/092360, WO 2005/012515 and WO 2007/024782). Tolerant towards glifosato plants can also be created by breeding plants that contain possess a natural origin of the mutation of the above genes (see, for example, international application WO 2001/024615 and WO 2003/013226).

Other herbicide-resistant plants are, for example, plants that given tolerantly towards inhibiting glutamine synthase herbicides, such as bialaphos, phosphinotricin or glufosinate. Such plants can be created by the expression of the enzyme neutralizing herbicide or resistant to inhibition of mutant glutamine synthase. Such neutralizing enzyme is, for example, the enzyme encoding phosphinotricin-acetyltransferase (e.g., bar or pat protein from Streptomyces species). Plants that will expriment exogenous phosphinothricin the n-acetyltransferase, described, for example, in U.S. patents US 5561236, US 5648477, US 5646024, US 5273894, US 5637489, US 5276268, US 5739082, US 5908810 and US 7112665.

Other tolerant to herbicides by plants are, for example, plants engineered tolerance to the inhibiting hydroxyphenylpyruvate (HPPD) herbicides. Under hydroxyphenylpyruvate involve enzymes that catalyse the conversion of para-hydroxyphenylpyruvate (NRR) homogentisate. Plants tolerant to HPPD inhibitors, can be transformed by the gene encoding resistant to HPPD enzyme of natural origin, or through gene encoding the mutated HPPD in accordance with international applications WO 1996/038567, WO 1999/024585 and WO 1999/024586. Tolerance to HPPD inhibitors can also be provided by transforming plants by genes encoding certain enzymes that contribute to the formation of homogentisate despite the inhibition of the natural enzyme HPPD HPPD inhibitor. Such plants and genes described in international applications WO 1999/034008 and WO 2002/36787. Tolerance of plants in relation to HPPD inhibitors can also be increased due to the fact that in addition to the transform through the gene encoding tolerant to HPPD enzyme, plants, Proc. of nsformer by encoding preventdisease gene (see, for example, international application WO 2004/024928).

Other Toleranti against herbicides plants are plants, which has tolerance to inhibitors acetolactate (ALS). To well-known ALS inhibitors include, for example, sulfanilamide, imidazoline, triazolopyrimidine, pyrimidinone(thio)benzoate and/or herbicides on the basis of sulfonamidophenylhydrazine. It is known that different mutations in the ALS enzyme (also called synthetase of acetohydroxyacid, AHAS) give the plants tolerance to different herbicides, respectively groups of herbicides (see, for example, Tranel and Wright, Weed Science (2002), 50, 700-712, as well as U.S. patents US 5605011, US 5378824, US 5141870 and US 5013659). The creation of a tolerant sulfanilamide and imidazolinone plants described in U.S. patent US 5605011, US 5013659, US 5141870, US 5767361, US 5731180, US 5304732, US 4761373, US 5331107, US 5928937 and US 5378824, as well as in the international application WO 1996/033270. Other tolerant towards imidazolinone plants are described, for example, in international applications WO 2004/040012, WO 2004/106529, WO 2005/020673, WO 2005/093093, WO 2006/007373, WO 2006/015376, WO 2006/024351 and WO 2006/060634. In addition, tolerant towards sulfanilamide and imidazolinone plants are described, for example, in international application WO 2007/024782.

Other tolerant towards imidazolinone and/or sulfanilamide plants can be sozdaniya induced mutagenesis, selection in cell cultures in the presence of the herbicide or mutation breeding, described, for example, in U.S. patent US 5084082 for soybean; international application WO 1997/41218 for rice, U.S. patent US 5773702 and international application WO 1999/057965 for sugar beet, U.S. patent US 5198599 for salad and international application WO 2001/065922 for sunflower.

Zadavaemymi biotechnology, such as gene technology, plants or parts of plants, which also can be subjected to processing proposed in the invention method, are resistant to damage from insects transgenic plants, i.e. plants engineered resistance against destruction by certain insects. Such plants can be created by genetic transformation or by selection of plants contain a mutation imparting resistance against pest damage.

Under transgenic plants resistant to pest damage, imply any plants that contain at least one transgene comprising a sequence which encodes the following protein:

1) an insecticidal crystal protein from Bacillus thuringiensis or an insecticidal portion, such as the insecticidal crystal proteins known from the article Crickmore and others, Microbiology and Molecular Biology Reviews (1998), 62, 807-813, and of opublikowany the th these authors item toxins of Bacillus thuhngiensis (2005) (http://www.lifesci.sussex.ac.uk/Home/Neil_Crickmore/Bt/), and insecticidal part of the proteins, for example proteins of the classes Cry1Ab, Cry1Ac, Cry1F, Cry2Ab, Cr3Ae or Cry3Bb or insecticidal part,

2) a crystal protein from Bacillus thuringiensis or part thereof that exhibits insecticidal activity in the presence of other crystal protein in Bacillus thuringiensis, or part thereof, in particular consisting of crystalline proteins Cy34 and Cy35 binary toxin (Moellenbeck and others, Nat. Biotechnol. (2001), 19, 668-72; Schnepf and others, Applied environment. Microb. (2006), 71, 1765-1774),

3) a hybrid insecticidal protein, which contains parts of two different insecticidal crystal proteins from Bacillus thuringiensis, for example, the hybrid protein according to paragraph 1) or a hybrid of the proteins in paragraph (2), in particular made from corn object MON98034 Cry1A.105 protein (international application WO 2007/027777),

4) protein is one of the above groups 1)-3)in which to improve insecticidal effectiveness against the target species of insects, expansion of the range of the target insect species and/or due to changes that were induced in the encoding DNA during cloning or transformation of individual amino acids, especially from 1 to 10 amino acids are substituted by another amino acid, in particular, protein Cry3Bb1 corn object MON863 or MON88017, or the Cry3A protein maize object MIR 604,

5) isolated from Bacillus thuringiensis or Bacillus cereus in acticity protein or an insecticidal portion, in particular, toxic to insect proteins with vegetative action (http://www.lifesci.sussex.ac.uk/Home/Neil_Crickmore/Bt/vip.html), for example, proteins from class VIP3Aa,

6) isolated from Bacillus thuringiensis or Bacillus cereus protein, which in the presence of another Bacillus thuringiensis or Bacillus cereus protein possesses insecticidal activity, in particular consisting of proteins VIP1A and VIP2A binary toxin (international application WO 1994/21795),

7) a hybrid insecticidal protein, containing parts of different Bacillus thuringiensis or Bacillus cereus proteins, in particular the hybrid proteins from group 1) or hybrid proteins from group 2), or

8) a protein of one of the above groups 1)-3)in which to improve insecticidal effectiveness against the target species of insects, expansion of the range of the target insect species and/or due to changes that were induced in the encoding DNA during cloning or transformation of individual amino acids, especially from 1 to 10 amino acids are substituted by another amino acid (saving coding for an insecticidal protein), in particular, the protein VIP3Aa in cotton HUNDRED object 102.

To transgenic plants that are resistant against pest damage, in this case, obviously, also include any plants that contain a combination of the genes encoding one of the proteins listed in the above groups 1)-8). In a preferred embodiment, the plant is resistant to damage from insects, contains more than one transgene encoding a protein of one of the above groups 1)-8), which allows to extend the range of the corresponding target insects or provides slow development of insect resistance against plant achieved thanks to the use of different proteins that have insecticidal activity against target insects of the same species, however, are characterized by a different principle, in particular, linking different parts of the receptor of an insect.

Plants or plant varieties that can be created by methods of biotechnology, particularly genetic engineering, and which can be subjected to processing proposed in the invention method, have the tolerance to abiotic stress factors. Such plants can be created by genetic transformation or by selection of plants that contain imparting stress resistance mutation. Particularly useful stress plants include the following:

A. plants which contain a transgene capable of reducing the expression and/or activity of a gene poly(ADP-ribose)polymerase (PARP) in plant cells or plants, for example as described in international application WO 2000/004173, as well as in the European patent EP 04077984.5 and EP 06009836.5,

b. plants that contain stimulating stress the transgene capable of reducing the expression and/or activity of the PARG encoding genes of the plants or plant cells, for example as described in international application WO 2004/090140,

C. plants containing stimulating stress the transgene, which encodes present in plants functional enzyme reutilization biosynthesis pathway of adenine dinucleotide, including nicotinamidase, negotiations.transfer, nicotinic acid-mononucleotides, nikotinamidadenindinukleotida or nicotine-amicroprocessor, for example as described in European patent EP 04077624.7, international application WO 2006/133827 or document PCT/EP 07/002433.

Plants or plant varieties that can be created by methods of biotechnology, particularly genetic engineering, and which can be subjected to processing proposed in the invention method, have altered the quantity, quality, suitability of the crop for storage and/or altered properties of specific components of the crop; relevant examples are the following plants.

1) Transgenic plants which synthesize a modified starch with modified physicochemical properties, primarily such is AK content of amylose, the ratio between aminosol and amylopectin, the degree of branching, the average length of the chains, the distribution of the side chains, rheological properties, the strength of the gel, and the size and/or morphological structure of the grains, and that sluchautsya of the relevant characteristics of the starch synthesized in the cells of wild type plants or wild plants, making such modified starch is better meets certain requirements. Such transgenic plants which synthesize a modified starch described, for example, in European patent EP 0571427, international application WO 1995/004826, European patent EP 0719338, international applications WO 1996/15248, WO 1996/19581, WO 1996/27674, WO 1997/11188, WO 1997/26362, WO 1997/32985, WO 1997/42328, WO 1997/44472, WO 1997/45545, WO 1998/27212, WO 1998/40503, WO 99/58688, WO 1999/58690, WO 1999/58654, WO 2000/008184, WO 2000/008185, WO 2000/28052, WO 2000/77229, WO 2001/12782, WO 2001/12826, WO 2002/101059, WO 2003/071860, WO 2004/056999, WO 2005/030942, WO 2005/030941, WO 2005/095632, WO 2005/095617, WO 2005/095619, WO 2005/095618, WO 2005/123927, WO 2006/018319, WO 2006/103107, WO 2006/108702, WO 2007/009823, WO 2000/22140, WO 2006/063862, WO 2006/072603 and WO 2002/034923, European patents EP 06090134.5, EP 06090228.5, EP 06090227.7, EP 07090007.1 and EP 07090009.7, international applications WO 2001/14569, WO 2002/79410, WO 2003/33540, WO 2004/078983, WO 2001/19975, WO 1995/26407, WO 1996/34968, WO 1998/20145, WO 1999/12950, WO 1999/66050 and WO 1999/53072, U.S. patent US 6 734 341, international applications WO 2000/11192, WO 1998/22604, WO 1998/32326, WO 2001/98509, WO 2001/98509 and WO 2005/002359, U.S. patent US 5 824 790 and US 6013 861, as well as in international applications WO 1994004693, WO 1994/009144, WO 1994/11520, WO 1995/35026 and WO 1997/20936.

2) Transgenic plants which synthesize polymers non-starch carbohydrates or polymers non-starch carbohydrates, whose properties are altered compared to wild type plants without genetic modification. Examples of such transgenic plants are plants that produce polymaltose first type of inulin and Levan, for example, described in European patent EP 0663956 and international applications WO 1996/001904, WO 1996/021023, WO 1998/039460 and WO 1999/024593, plants producing alpha-1,4-glucan, for example, described in international application WO 1995/031553, U.S. patent US 2002/031826, US 6284479 and US 5 712107, international applications WO 1997/047806, WO 1997/047807, WO 1997/047808 and WO 2000/14249, plants producing alpha-1,6 branched alpha-1,4-glucan, for example, described in the international application WO 2000/73422, and plants that produce alternan, for example, described in international application WO 2000/047727, European patent EP 06077301.7, U.S. patent US 5908 975 and European patent EP 0728213.

3) Transgenic plants which produce hyaluronic acid, for example, described in international applications WO 2006/032538, WO 2007/039314, WO 2007/039315, WO 2007/039316, WO 2005/012529 and Japanese patent JP 2006/304779.

In addition, to plants or plant varieties that can be created by methods of biotechnology, in particular genetic engineering, and which can be subjected to the processing is TKE proposed in the invention method, includes, for example, cotton with modified properties of the fibers. Such plants can be created by genetic transformation or by selection of plants containing a mutation that causes the change of properties of the fibers; such plants are:

a) plants, such as cotton plants, containing an altered form of the gene celluoseacetate and described, for example, in international application WO 1998/000549,

b) plants such as cotton plants, containing an altered form of homologues of rsw2 or rsw3 nucleic acids and are described, for example, in international application WO 2004/053219,

c) plants such as cotton plants, with increased expression saharozameniteley described, for example, in international application WO 2001/017333,

d) plants such as cotton plants, with increased expression of saharacasino described, for example, in international application WO 02/45485,

e) plants such as cotton plants, with time regulation transmittance plasmodesma cell-based fiber, modified, for example, by regulating the dependent fibers β-1,3-glucanase as described, for example, in international application WO 2005/017157,

f) plants, such as cotton, the reactivity of the fibers is changed, for example, by the expression of gene N-acetylglycine-aminotransferase, including nodC and genes citysites described, for example, in the international the Noi application WO 2006/136351.

To plants or plant varieties that can be created by methods of biotechnology, particularly genetic engineering, and which can be subjected to processing proposed in the invention method are also plants with modified properties of the oils, such as canola or plants, related Brassica. Such plants can be created by genetic transformation or by selection of plants contain a mutation that provides change properties of oils; such plants are:

a) plants, in particular rape, which produce oil with high oleic acid content, for example, described in U.S. patent US 5969169, US 5840946, US 6323392 and US 6063947,

b) plants, in particular, pane, which produce oil with a low content of linolenic acid, for example, described in U.S. patent US 6270828, US 6169190 and US 5965755,

c) plants, in particular rape, which produce oil with low content of saturated fatty acids, for example, described in U.S. patent US 5434283.

Particularly useful transgenic plants which can be subjected to processing proposed in the invention method, are plants with one or more genes encoding one or more toxins, supplied to the market under the trade names YIELD GARD®(for example, corn, cotton, soybeans), KnockOut®(for example maize), BiteGard®(for example maize), BT-Xtra®(for example maize), StarLink®(for example maize), Bollgard®(cotton), Nucotn®(cotton), Nucotn 33B®(cotton), NatureGard®(for example maize), Protecta®and NewLeaf®(potatoes). Tolerant to herbicides by plants are, for example, maize, cotton and soya, supplied under the trade names Roundup Ready®(for example, tolerant glyphosate corn, cotton and soybeans), Liberty Link®(for example, tolerance to phosphinotricin pane), IMI®(tolerance imidazolinone) and SCS®(tolerance sulfanilamide), for example, corn. To resistant to herbicides plants (traditionally cultivated tolerant to herbicides (plants), which in this case should be mentioned include the varieties supplied under the trade name Clearfield®(for example, corn).

Particularly useful transgenic plants which can be subjected to processing proposed in the invention method are plants containing objects of transformation or combination of objects of transformation, which, for example, included in the database of different national or regional institutions (see, for example, http://gmoinfo.jrc.it/gmp_browse.aspx, http://www.agbios.com/dbase.php).

The above plants especially the site the preferably you can process proposed in the invention combinations of active substances. For the preferred treatment of these plants use a combination of active substances mentioned above as preferred. Particularly noteworthy is the treatment of plants with combinations of active substances referred to in this description as a special.

Proposed in the invention combination of active ingredients effective not only against plant pests, household pests and pests of the stocks, but with zooparasitic (ecto - and endoparasite), which are objects of veterinary medicine, such as pasture, Ixodes and cestocide mites, krasnoselka, biting or licking flies parasitizing larvae of flies, lice, ect., hematophagous biting and fleas. Such cooperation include representatives of the following groups and classes.

Corps representatives Anoplurida, for example Haematopinus spp., Linognathus spp., Pediculus spp., Phtirus spp., Solenopotes spp.

Corps representatives Mallophagida and suborders Amblycenna and Ischnocerina, for example, Trimenopon spp., Menopon spp., Trinoton spp., Bovicola spp., Wemeckiella spp., Lepikentron spp., Damalina spp., Trichodectes spp., Felicola spp.

The representatives of the order Diptera and the suborders Nematocerina and Brachycerina, for example, Aedes spp., Anopheles spp., Culex spp., Simulium spp., Eusimulium spp., Phlebotomus spp., Lutzomyia spp., Culicoides spp., Chrysops spp., H. spp., Atylotus spp., Tabanus spp., Haematopota spp., Philipomyia spp., Braula spp., Musca spp., Hydrotaea spp., Stomoxys spp., Haematobia spp., Morellia spp., Fannia spp., Glossina spp., Calliphora spp., Lucilia spp., Chrysomyia spp., Wohlfahrtia spp., Sarcophaga spp., Oestrus spp., Hypderma spp., Gasterophilus spp., Hippobosca spp., Lipoptena spp., Melophagus spp.

Corps representatives Siphonapterida, for example, Pulex spp., Ctenocephalides spp., Xenopsylla spp., Ceratophyllus spp.

Corps representatives Heteropterida, for example, Cimex spp., Triatoma spp., Rhodnius spp., Panstrongylus spp.

Corps representatives Blattarida, for example, Blatta orientalis, Periplaneta americana, Blattela germanica, Supella spp.

Representatives of the subclass Acari (Acaiina), as well as units Metastigmata and Mesostigmata, for example Argas spp., Omithodorus spp., Otobius spp., Ixodes spp., Amblyomma spp., Boophilus spp., Dermacentor spp., Haemophysalis spp., Hyalomma spp., Rhipicephalus spp., Dermanyssus spp., Raillietia spp., Pneumonyssus spp., Sternostoma spp., Varroa spp.

Representatives of the detachment of the Actinedida (Prostigmata) and Acaridida {Astigmata), for example, Acarapis spp., Cheyletiella spp., Ornithocheyletia spp., Myobia spp., Psorergates spp., Demodex spp., Trombicula spp., Listrophorus spp., Acarus spp., Tyrophagus spp., Caloglyphus spp., Hypodectes spp., Pterolichus spp., Psoroptes spp., Chorioptes spp., Otodectes spp., Sarcoptes spp., Notoedres spp., Knemidocoptes spp., Cytodites spp., Laminosioptes spp.

Proposed in the invention combination of active substances are also suitable for combating arthropods affecting the useful agricultural animals such as cows, sheep, goats, horses, pigs, donkeys, camels, Buffalo, rabbits, chickens, turkeys, ducks, geese, honeybees, other domestic animals such as dogs, cats, pet birds and aquarium fish, and so-called laboratory animals, such as hamsters, Guinea pigs, rats and mice. Combating arthropods such reduces the number of years is selected outcomes in animals and increase their productivity, meat, milk, wool, hides, eggs, honey and so forth, and, consequently, through the use proposed in the invention combinations of active substances are provided the opportunity to more cost-effective and simple animals.

Proposed in the invention combination of active substances used in veterinary medicine known methods enteral application, for example, in the form of tablets, capsules, medicines, oral doses, granules, pastes, pills, medicated feed and candles, methods of parenteral administration, such as intramuscular, subcutaneous, intravenous, intraperitoneal and other injections, implants, by nazalnogo or dermal application, for example, dipping or immersion, spraying aerosols, water (total or partial), bathing, dusting, and by containing active substances molded products, such as cervical headbands, ear or tail tag, headbands limbs, clamps, marking devices and other products of similar type.

The combination of active substances can be used for veterinary treatment of agricultural animals and birds, Pets and so on in the form of drugs (for example, Farrukh Dustov, emulsions, spreading funds)containing from 1 to 80 wt%. active substances, either directly or after RA is bauleni, the multiplicity of which is from 100 to 10000, as well as chemical baths.

In addition, there is a strong insecticidal effect proposed in the invention combinations of active substances on insects, destructive technical materials.

Examples of such insects, not limited to the following list, preferable are the following:

Coleoptera beetles, such as Hylotrupes bajulus, Chlorophorus pilosis, Anobium punctatum, Xestobium rufovillosum, Ptilinus pecticomis, Dendrobium pertinex, Ernobius mollis, Priobium carpini, Lyctus brunneus, Lyctus africanus, Lyctus planicollis, Lyctus linearis, Lyctus pubescens, Trogoxylon aequale, Minthes rugicollis, Xyleborus spec., Tryptodendron spec., Apate monachus, Bostrychus capucins, Heterobostrychus brunneus, Sinoxylon spec., Dinoderus minutus,

hymenopterous insects, such as Sirex juvencus, Urocerus gigas, Urocerus gigas taignus, Urocerus augur,

termites, such as Kalotermes flavicollis, Cryptotermes brevis, Heterotermes indicola, Reticulitermes flavipes, Reticulitermes santonensis, Reticulitermes lucifugus, Mastotermes darwiniensis, Zootermopsis nevadensis, Coptotermes formosanus,

Seinajoki, such as Lepisma sacchahna.

Under technical materials involve inanimate materials, preferably polymers, adhesives, glues, paper, cardboard, leather, wood, products of wood processing and coating materials.

Ready-to-use tools when necessary, may additionally contain other insecticides and, if necessary, one or more fungicides.

Possible additional componentui such funds are above insecticides and fungicides.

In addition, the proposed in the invention combination of active substances can be used for protection against fouling of various objects, primarily hull, screening grids, networks, building structures, mooring facilities and alarm devices in contact with sea water or river water mixed with the sea.

In addition, the proposed in the invention combination of active ingredients, either alone or in combination with other active substances, can be used as anti-fouling means.

Proposed in the invention combination of active substances are also suitable for control of noxious animals, especially insects, arachnids and mites, in enclosed spaces, such as apartments, industrial plants, offices, cars and other confined spaces. To combat these harmful animals they can be used individually or in combination with other active substances and additives contained in household insecticide products. Proposed in the invention combination of active ingredients effective against sensitive and resistant species of noxious animals at any stage of their development. Such harmful animals include representatives of the following groups:

squad of Scorpions, for example, Buthus occitanus,

detachment of ticks, for example, Argas persicus, Argas reflexus, Bryobia ssp., Dermanyssus gallinae, Glyciphagus domesticus, Omithodorus moubat, Rhipicephalus sanguineus, Trombicula alfreddugesi, Neutrombicula autumnalis, Dermatophagoides pteronissimus, Dermatophagoides forinae,

squad of spiders, for example, Aviculariidae, Araneidae,

detachment Pestryakov, for example, Pseudoscorpiones chelifer, Pseudoscorpiones cheiridium, Opiliones phalangium,

detachment isopods insects, for example, Oniscus asellus, Porcellio scaber,

detachment of insects, for example, Blaniulus guttulatus, Polydesmus spp.,

troop Gubanova, for example, Geophilus spp.,

detachment Zygentoma, for example, Ctenolepisma spp., Lepisma saccharina, Lepismodes inquilinus,

detachment cockroaches, for example, Blatta orientalies, Blattella germanica, Blattella asahinai, Leucophaea maderae, Panchlora spp., Parcoblatta spp., Periplaneta australasiae, Periplaneta amehcana, Periplaneta brunnea, Periplaneta fuliginosa, Supella longipalpa,

squad jumping, orthopterous insects, for example, Acheta domesticus, detachment historylink insects, for example, Forficula auricularia, detachment termites, for example, Kalotemnes spp., Reticulitermes spp., detachment of Sendov, for example, Lepinatus spp., Liposcelis spp.,

detachment of Coleoptera, for example, Anthrenus spp., Attagenus spp., Dermestes spp., Latheticus oryzae, Necrobia spp., Ptinus spp., Rhizopertha dominica, Sitophilus granahus, Sitophilus oryzae, Sitophilus zeamais, Stegobium paniceum,

detachment of the Diptera, for example Aedes aegypti, Aedes albopictus, Aedes taeniorhynchus, Anopheles spp., Calliphora erythrocephala, Chrysozona pluvialis, Culex quinquefasciatus, Culex pipiens, Culex tarsalis, Drosophila spp., Fannia canicularis, Musca domestica, Phlebotomus spp., Sarcophaga camaria, Simulium spp., Stomoxys calcitrans, Tipula paludosa,

detachment of Lepidoptera, for example, Achroia ghsella, Galleria ellonella, Plodia interpunctella, Tinea cloacella, Tinea pellionella, Tineola bisselliella,

detachment fleas, for example, Ctenocephalides canis, Ctenocephalides felis, Pulex irhtans, Tunga penetrans, Xenopsylla cheopis,

detachment of hymenopterous insects, for example, Camponotus herculeanus, Lasius fuliginosus, Lasius niger, Lasius umbratus, Monomorium pharaonis, Paravespula spp., Tetramonum caespitum,

detachment lice, for example, Pediculus humanus capitis, Pediculus humanus corporis, Phthirus pubis,

detachment bugs, for example, Cimex hemipterus, Cimex lectularius, Rhodinus prolixus, Triatoma infestans.

The application of the proposed invention in combinations of active substances in the domestic sphere carried out individually or in combination with other suitable active substances, such as phosphonates, carbamates, pyrethroids, neonicotinoids and plant growth regulators, or in combination with active substances from other known classes of insecticides.

The application is carried out in the form of aerosols sprayed without pressure means (e.g., sprays with a manual swap or spray), fogging machines and aerosol sprayers, in the form of foams, gels, products of evaporation by means of evaporation plates of cellulose or polymer, gidrostroitelei, gel, diaphragm and propeller evaporators, passive, and therefore not consuming energy systems evaporation, in the form of protection from insects paper strips, bags and gels, as well as in the form of granulates or powder etc the preparations poisoned baits for spreading or in bait strips.

The following examples show high insecticidal effectiveness of the proposed invention in combinations of active substances. From the examples it follows that the individual active substances have low efficiencies, while their combination is characterized by efficiency, exceeding the result of a simple summation.

Insecticides have a synergistic effect in that case if the efficiency of the combination of active ingredients is greater than the sum of the efficacies individually applied active substances.

The expected effectiveness of a combination of two active compounds can be calculated according S.R.Colby, Weeds, 15 (1967), 20-22 as follows.

Provided that:

X indicates the degree of samaritane when using the active substance And with a rate of m g/ha or in a concentration of m (m-1), expressed relative to the control experiment (without processing),

Y means the degree of samaritane when using the active substance In at a rate of n g/ha or in a concentration of n (m-1), expressed relative to the control experiment (without processing), and

E indicates the degree of samaritane with joint use of active substances a and b with the norms of consumption with the responsible type (g/ha) or in concentrations of, respectively, m and n (m -1), expressed relative to the control experiment (without processing),

the degree of samaritane E can be calculated according to the Colby formula:

E=X+YXY100.

If the actual insecticidal or acaricidal degree of samaritane exceeds calculated from the formula value, we are talking about vergadain effect samaritane through a combination of active substances, i.e. a synergistic effect. In this case, the actually observed degree of samaritane exceed calculated by the above formula, the degree of samaritane (E).

Used in the following examples soedineniya the above formulas (I) 4-{[(6-chloropyrid-3-yl)methyl](2-foradil)amino}-furan-2(5H) -, 4-{[(6-chloropyrid-3-yl)methyl](2,2-dottorati)amino}-furan-2(5H)-4-{[(6-chloro-5-forperiod-3-yl)methyl](methyl)amino}-furan-2(5H)-he referred to as compounds (1-4), (1-5) and (1-6), respectively.

Example A. Test with peach aphid Myzus persicae

Solvent:78 mass acetone,
1,5 mass of dimethylformamide.
Emulsifier:0,5 mass of alkylaromatics.

For the purpose of preparation suitable for use of the drug one mass part of the active substance is mixed with the stated amounts of solvent and emulsifier, and the resulting concentrate is diluted with emulsifier with water to the desired concentration of the active substance.

The leaves of cabbage Brassica oleracea strongly affected aphid green peach (Myzus persicae), treated by spraying used in the necessary concentration of the drug active substance.

After the necessary time to determine the degree of samaritane aphids in percent. 100% corresponds to complete samaritani, whereas 0% indicates complete absence of samaritane. Specific values of the degree of samaritane substituted in the above formula Colby.

In this example, detected a synergistic enhancement of the effectiveness of the present invention combinations of active ingredients compared to the effectiveness of individually applied active substances (see table A).

Table a
Damage to the plants aphids Myzus persicae
The current wishes is in Concentration, g/haSamaritana after 1 day, %
The compound (I-4)430
0,80
The compound (I-5)0,810
Emamectin-benzoate0,160
Amiprol40
Fipronil2030
Flonicamid0,80
Indoxacarb200
Rynaxypyr0,80
The compound (I-4)+emamectin-benzoate (25:1) (according to the SNO invention) 4+0,16Found* 50Calculated** 30
The compound (I-4)+ethiprole (1:5) (according to the invention)0,8+4Found* 20Calculated** 0
The compound (I-4)+fipronil (1:5) (according to the invention)4+20Found* 99Calculated** 51
The compound (I-4)+flonicamid (1:1) (according to the invention)4+4Found* 80Calculated** 30
The compound (I-5)+flonicamid (1:1) (according to the invention)0,8+0,8Found* 50Calculated** 10
The compound (I-4)+indoxacarb (1:5) (according to the invention)4+20Found* 80Calculated** 30
The compound (I-4)+rynaxypyr (5:1) (according to the invention)4+0,8Found* 80Calculated** 30
* The observed effect
** Effect calculated by the Colby formula

The compound (I-4)+diafenthiuron (1:1) (according to the invention)
Table a (continued)
Damage to the plants aphids Mvzus persicae
The active ingredientConcentration, g/haSamaritana after 6 days, %
The compound (I-6)0,870
0,160
The compound (I-4)0,80
Amiprol40
Fipronil0,80
Metaflumizone0,80
Rynaxypyrto 0.0320
the Compound (I-6)+ethiprole (1:5) (according to the invention) 0,8+4Found* 90Calculated** 70
The compound (I-6)+fipronil (1:5) (according to the invention)0,16+0,8Found* 40Calculated** 0
The compound (I-4)+metaflumizone (1:1) (according to the invention)0,8+0,8Found* 50Calculated** 0
The compound (I-6)+rynaxypyr (5:1) (according to the invention)0,16+0,032Found* 40Calculated** 0
* The observed effect
** Effect calculated by the Colby formula
Table a (continued)
Damage to the plants aphids Mvzus persicae
The active ingredientConcentration, g/haSamaritana after 1 day, %
The compound (I-6)0,160
The compound (I-4) 430
The compound (I-5)470
The abamectin0,160
Amitraz40
Chlorfenapyr40
Canoperate40
Titlemotion40
Cyromazine40
The active ingredientConcentration, g/haSamaritana after 1 day, %
Diafenthiuron40
Fenpyroximate40
Milbemectin0,16/td> 0
Pymetrozine0,160
The compound (I-4)+abamectin (25:1) (according to the invention)4+0,16Found* 70Calculated** 30
The compound (I-4)+amitraz (1:1) (according to the invention)4+4Found* 70Calculated** 30
The compound (1-4)+chlorfenapyr (1:1) (according to the invention)4+4Found* 80Calculated** 30
The compound (I-4)+canoperate (1:1) (according to the invention)4+4Found* 50Calculated** 30
The compound (I-4)+titlemotion (1:1) (according to the invention)4+4Found* 80Calculated** 30
The compound (I-5)+cyromazine (1:1) (according to the invention)4+4Found* 90Calculated** 70
4+4Found* 70Calculated** 30
The compound (1-4)+fenpyroximate (1:1) (according to the invention)4+4Found* 80Calculated** 30
The compound (I-6)+milbemectin (25:1) (according to the invention)4+0,16Found* 60Calculated** 0
The compound (I-6)+pymetrozine (1:1) (according to the invention)0,16+0,16Found* 20Calculated** 0
The compound (I-4)+pymetrozine (1:1) (according to the invention)4+4Found* 90Calculated** 30
* The observed effect
** Effect calculated by the Colby formula
Table a (continued)
Damage to the plants aphids Myzus persicae
The active ingredientConcentration, the/ha Samaritana after 6 days, %
The compound (I-4)460
The compound (I-5)0,810
The active ingredientConcentration, g/haSamaritana after 6 days, %
Pymetrozine0,850
Spinosad0,80
The compound (I-5)+pymetrozine (1:1) (according to the invention)0,8+0,8Found* 80Calculated** 55
The compound (I-4)+spinosad (1:1) (according to the invention)4+0,8Found* 90Calculated** 60
* The observed effect
** Effect calculated by the Colby formula

Example Century. Test with larvae of Phaedon cochleanae

Solvent:78 mass acetone,
1,5 mass of dimethylformamide.
Emulsifier0,5 mass of alkylaromatics.

For the purpose of preparation suitable for use of the drug one mass part of the active substance is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier with water to the desired concentration of the active substance.

The leaves of cabbage Brassica oleracea is sprayed with a preparation of active ingredient in the required concentration and while they are still wet inhabit the larvae of leaf shitty (Phaedon cochleanae).

After the necessary time to determine the degree of samaritane larvae in percent. 100% corresponds to complete samaritani, whereas 0% indicates complete absence of samaritane. Specific values of the degree of samaritane substituted in the above formula Colby.

In this example, detected a synergistic enhancement of the effectiveness of the present invention combinations of active ingredients compared to the effectiveness of individually applied active substances (see table).

Table
Test with larvae of Phaedon cochleariae
The active ingredientConcentration, g/haSamaritana 2 days, %
The compound (I-6)0,80
The compound (I-5)0,80
Emamectin-benzoateto 0.0320
The compound (I-6)+emamectin-benzoate (25:1) (according to the invention)0,8+0,032Found* 33Calculated** 0
The compound (I-5)+emamectin-benzoate (25:1) (according to the invention)0,8+0,032Found* 50Calculated** 0
* The observed effect
** Effect calculated by the Colby formula
Table V (continued)
Test with larvae of Phaedon cochleariae
The active ingredientConcentration, g/haSamaritana after 6 days, %
The compound (I-6)1000
200
0,80
0,160
The active ingredientConcentration, g/haSamaritana after 6 days, %
The compound (I-4)1000
200
0,80
The compound (I-5)1000
0,80
0,160
Amiprol467
0,833
Flonicamid1000
Indoxacarb433
0,80
Metaflumizone1000
Rynaxypyr450
The compound (I-6)+ethiprole (1:5) (according to the invention)0,8+4Found* 83Calculated** 67
The compound (I-4)+ethiprole (1:5) (according to the invention) 0,8+4Found* 100Calculated** 67
The compound (I-5)+ethiprole (1:5) (according to the invention)0,16+0,8Found* 67Calculated** 33
The compound (I-6)+flonicamid (1:1) (according to the invention)100+100Found* 100Calculated** 33
The compound (I-4)+flonicamid (1:1) (according to the invention)100+100Found* 83Calculated** 33
The compound (I-5)+flonicamid (1:1) (according to the invention)100+100Found* 100Calculated** 33
The compound (I-6)+indoxacarb (1:5) (according to the invention)0,16+0,8Found* 17Calculated** 0
The compound (I-5)+indoxacarb (1:5) (according to the invention)0,8+4Found* 83Calculated** 33
The compound (I-6)+metaflumizone (1:1) (according to the invention) 100+100Found* 100Calculated** 0
The compound (I-4)+metaflumizone (1:1) (according to the invention)100+100Found* 100Calculated** 0
The compound (1-5)+metaflumizone (1:1) (according to the invention)100+100Found* 100Calculated** 0
The compound (I-6)+rynaxypyr (5:1) (according to the invention)20+4Found* 83Calculated** 50
The compound (I-4)+rynaxypyr (5:1) (according to the invention)20+4Found* 83Calculated** 50
* The observed effect
** Effect calculated by the Colby formula
Table V (continued)
Test with larvae of Phaedon cochleariae
The active ingredientConcentration, g/haSamaritana 2 days, %
The compound (I-6)10033
The compound (I-4)10033
The compound (I-5)10050
The abamectin467
Chlorfenapyr10067
Tebufenpyrad10050
The compound (I-6)+abamectin (25:1) (according to the invention)100+4Found* 100Calculated** 77,89
The compound (I-4)+abamectin (25:1) (according to the invention)100+4Found* 100Calculated** 77,89
The compound (I-5)+abamectin (25:1) (according to the invention)100+4Found* 100Calculated** 83,5
The compound (I-6)+chlorfenapyr (1:1) (according to the invention)100+100Found* 100Calculated** 33
The compound (I-4)+chlorfenapyr (1:1) (according to the invention)100+100Found* 100Calculated** 33
The compound (I-5)+chlorfenapyr (1:1) (according to the invention)100+100Found* 100Calculated** 50
The compound (I-6)+tebufenpyrad (1:1) (according to the invention)100+100Found* 83Calculated** 50
The compound (I-4)+tebufenpyrad (1:1) (according to the invention)100+100Found* 67Calculated** 50
The compound (I-5)+tebufenpyrad (1:1) (according to the invention)100+100Found* 83Calculated** 50
* The observed effect
** Effect calculated by the Colby formula
Table V (continued)
Test with larvae of Phaedon cochleariae
The active ingredientConcentration, g/haSamaritana after 6 days, %
The compound (1-6)200
40
The compound (I-4)10033
200
The compound (I-5)10033
200
Amitraz1000
Canoperate1000
Titlemotion 1000
Cyromazine1000
200
IKA 20021000
200
Pymetrozine1000
Pyridaben1000
Spinosad0,850
The compound (I-4)+amitraz (1:1) (according to the invention)100+100Found* 83Calculated** 33
The compound (I-4)+canoperate (1:1) (according to the invention)100+100Found* 50Calculated** 33
The compound (I-5)+canoperate (1:1) (according to the invention)100+100Found* 67Calculated** 33
The compound (I-4)+titlemotion (1:1) (according to the invention)100+100Found* 50Calculated** 33
The compound (I-5)+titlemotion (1:1) (according to the invention)100+100Found* 100Calculated** 33
The compound (I-6)+cyromazine (1:1) (according to the invention)20+20Found* 33Calculated** 0
The compound (I-5)+cyromazine (1:1) (according to the invention)100+100Found* 50Calculated** 33
The compound (I-6)+IKA 2002 (1:1) (according to the invention)20+20Found* 33Calculated** 0
The compound (I-5)+IKA 2002 (1:1) (according to the invention)100+100Found* 67Calculated** 33
the Compound (I-6)+pymetrozine (1:1) (according to the invention) 100+100Found* 67Calculated** 33

The active ingredientConcentration, g/haSamaritana after 6 days, %
The compound (I-5)+pymetrozine (1:1) (according to the invention)100+100Found* 100Calculated** 33
The compound (I-6)+pyridaben (1:1) (according to the invention)20+20Found* 33Calculated** 0
The compound (I-4)+pyridaben (1:1) (according to the invention)20+20Found* 33Calculated** 0
The compound (I-5)+pyridaben (1:1) (according to the invention)20+20Found* 83Calculated** 0
The compound (I-5)+spinosad (5:1) (according to the invention)4+0,8Found* 83Calculated** 50
* Obnaruzhennykh
** Effect calculated by the Colby formula

Example C. the Test with larvae of Spodoptera frugiperda

Solvent:78 mass acetone,
1,5 mass of dimethylformamide.
Emulsifier:0,5 mass of alkylaromatics.

For the purpose of preparation suitable for use of the drug one mass part of the active substance is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier with water to the desired concentration of the active substance.

The leaves of cabbage Brassica oleracea is sprayed with a preparation of active ingredient in the required concentration and while they are still wet inhabit the larvae of Spodoptera frugiperda.

After the necessary time to determine the degree of samaritane larvae in percent. 100% corresponds to complete samaritani, whereas 0% indicates complete absence of samaritane. Specific values of the degree of samaritane substituted in the above formula Colby.

In this example, detected a synergistic enhancement of the effectiveness of the present the image the structure of combinations of active ingredients compared to the effectiveness of individually applied active substances (see table).

Table
Test with larvae of Spodoptera fruoiperda
The active ingredientConcentration, g/haSamaritana 2 days, %
The compound (I-6)200
Emamectin-benzoate0,850
The compound (I-6)+emamectin-benzoate (1:1) (according to the invention)20+0,8Found* 67Calculated** 50
* The observed effect
** Effect calculated by the Colby formula
Table (continued)
Test with larvae of Spodoptera fruaiperda
The active ingredientConcentration, g/haSamaritana after 6 days, %
The compound (I-6) 200
0,80
The compound (I-4)1000
0,80
0,160
The compound (I-5)200
0,80
0,160
Fipronil0,817
Indoxacarb483
0,833
Metaflumizone 10083
200
Rynaxypyr0,1633
The compound (I-5)+fipronil (1:5) (according to the invention)0,16+0,8Found* 33Calculated** 17
The compound (I-6)+indoxacarb (1:5) (according to the invention)0,8+4Found* 100Calculated** 83
The compound (I-4)+indoxacarb (1:5) (according to the invention)0,16+0,8Found* 50Calculated** 33
The compound (I-5)+indoxacarb (1:5) (according to the invention)0,8+4Found* 100Calculated** 83
The compound (I-6)+metaflumizone (1:1) (according to the invention)20+20Found* 50Calculated** 0
The active ingredient Concentration, g/haSamaritana after 6 days, %
The compound (I-4)+metaflumizone (1:1) (according to the invention)100+100Found* 100Calculated** 83
The compound (I-5)+metaflumizone (1:1) (according to the invention)20+20Found* 33Calculated** 0
The compound (I-6)+rynaxypyr (5:1) (according to the invention)0,8+0,16Found* 83Calculated** 33
The compound (I-4)+rynaxypyr (5:1) (according to the invention)0,8+0,16Found* 67Calculated** 33
* The observed effect
** Effect calculated by the Colby formula
Table (continued)
Test with larvae of Spodoptera fruqiperda
The active ingredientConcentration, g/haSamaritana 2 days, %
The compound (I-6)200
40
The compound (I-4)200
40
The compound (I-5)200
40
Chlorfenapyr2033
Spinosad0,80
The compound (I-6)+chlorfenapyr (1:1) (according to the invention)20+20Found* 83Calculated** 33
The compound (I-4)+chlorfenapyr (1:1) (according to the invention)20+20Found* 50/td> Calculated** 33
The compound (I-5)+chlorfenapyr (1:1) (according to the invention)20+20Found* 83Calculated** 33
The compound (I-6)+spinosad (5:1) (according to the invention)4+0,8Found* 33Calculated** 0
The compound (I-4)+spinosad (5:1) (according to the invention)4+0,8Found* 33Calculated** 0
The compound (I-5)+spinosad (5:1) (according to the invention)4+0,8Found* 33Calculated** 0
* The observed effect
** Effect calculated by the Colby formula

Example D. Test resistant to orthophosphate spider mite Tetranychus urticae

Solvent:78 mass acetone,
1,5 massof dimethylformamide.
Emulsifier:0.5 wt.is. alkylaromatics.

For the purpose of preparation suitable for use of the drug one mass part of the active substance is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier with water to the desired concentration of the active substance.

Round die-cut from sheets of bean (Phaseolus vulgaris)affected all stages of the spider mite (Tetranychus urticae), are sprayed with a preparation of active ingredient at the desired concentration.

After the necessary time to determine the degree of samaritane larvae in percent. 100% corresponds to complete samaritani, whereas 0% indicates complete absence of samaritane.

In this example, detected a synergistic enhancement of the effectiveness of the present invention combinations of active ingredients compared to the effectiveness of individually applied active substances (see table D).

Pyridaben 4+4
Table D
Test spider mite Tetranychus urticae
The active ingredientConcentration, g/haPacking in 2 days, %
With the Association (I-6) 200
0,160
The compound (I-4)200
40
0,80
The compound (I-5)40
0,160
The abamectin0,006450
Canoperate0,850
0,160
Diafenthiuron1000
2050
Spinosad420
Tebufenpyrad410
The compound (I-6)+abamectin (25:1) (according to the invention)0,16+0,0064Found* 70Calculated** 50
The compound (I-5)+abamectin (25:1) (according to the invention)0,16+0,0064Found* 70Calculated** 50
The compound (I-4)+canoperate (1:1) (according to the invention)0,8+0,8Found* 90Calculated** 50
The compound (I-5)+canoperate (1:1) (according to the invention)0,16+0,16Found* 20Calculated** 0
The compound (I-4)+diafenthiuron (1:1) (according to the invention)100+100Found* 90Calculated** 0
The compound (I-5)+diafenthiuron (1:1) (according to the invention)100+100Found* 50Calculated** 0
The compound (I-4)+pyridaben (1:1) (according to the invention)20+20Found* 80Calculated** 50
The compound (I-6)+spinosad (5:1) (according to the invention)20+4Found* 40Calculated** 20
The compound (I-4)+spinosad (5:1) (according to the invention)20+4Found* 50Calculated** 20
The active ingredientConcentration, g/haSamaritana 2 days, %
The compound (I-4)+tebufenpyrad (1:1) (according to the invention)4+4Found* 30Calculated** 10
The compound (I-5)+tebufenpyrad (1:1) (according to the invention)4+4Found* 30Calculated** 10
* Find the config effect
** Effect calculated by the Colby formula
Table D (continued)
Test spider mite Tetranychus urticae
The active ingredientConcentration, g/haSamaritana after 6 days, %
The compound (I-6)10050
40
The compound (I-4)40
The compound (I-5)40
Titlemotion470
Diafenthiuron1000
Fenpyroximate40
Milbemectin 0,160
The compound (I-6)+titlemotion (1:1) (according to the invention)4+4Found* 100Calculated** 70
The compound (I-4)+titlemotion (1:1) (according to the invention)4+4Found* 100Calculated** 70
The compound (I-5)+titlemotion (1:1) (according to the invention)4+4Found* 100Calculated** 70
The compound (I-6)+diafenthiuron (1:1) (according to the invention)100+100Found* 100Calculated** 50
The compound (I-6)+fenpyroximate (1:1) (according to the invention)4+4Found* 40Calculated** 0
The compound (I-4)+fenpyroximate (1:1) (according to the invention)4+4Found* 40Calculated** 0
The compound (I-5)+fenpyroximate (1:1) (according to the invention)Found* 70Calculated** 0
The compound (I-6)+milbemectin (25:1) (according to the invention)4+0,16Found* 30Calculated** 0
The compound (I-4)+milbemectin (25:1) (according to the invention)4+0,16Found* 70Calculated** 0
The compound (I-5)+milbemectin (25:1) (according to the invention)4+0,16Found* 90Calculated** 0
* The observed effect
** Effect calculated by the Colby formula

1. Insecticidal combination of active substances containing at least one compound of formula (I):
,
in which a represents 6-forperiod-3-yl and R1mean 2-foradil or 2,2-dottorati, or a represents 5-fluoro-6-chloropyrid-3-yl and R1means methyl, and at least one compound selected from the group consisting of:
(1) spinosad,
(2) abamectin,
(3) emamectin-benzoate,
(4) milbemectin,
(5) indoxacarb,
(6) fipronil,
(7) ethiprole,
(8) horfe apira,
(9) diafenthiuron,
(10) tebufenpyrad,
(11) fenpyroximate,
(12) cyanopyridine,
(13) titlemotion,
(14) amitraz,
(15) cyromazine,
(16) pyridaben,
(17) flonicamid,
(18) pymetrozine,
(19) periglaciation,
(20) rynaxypyr,
(21) caipira,
(22) metaflumizone,
(23) O-{(E)-2-(4-chlorophenyl)-2-cyano-1-[2-(trifter-methyl)phenyl]ethynyl}-S-methylthiocarbamate.

2. The use of combinations of active substances according to claim 1 for control of noxious animals.

3. The use of combinations of active substances according to claim 1 for the treatment of seed material or transgenic plant or seed material of transgenic plants.

4. Seeds subjected to processing with a combination of active substances according to claim 1.

5. Seed material according to claim 4, subjected to the simultaneous processing of the active substance of the formula (I) and one of the active substances from the specified group.

6. Seed material according to claim 4, processed active substance of the formula (I) and one of the active substances in this group performed at different points in time.



 

Same patents:

FIELD: chemistry.

SUBSTANCE: invention relates to compound of formula 1

, where R1 represents halogen, C1-C2halogenalkyl or C1-C2halogenalkoxy; R2 represents H, halogen; R3 represents H, halogen or CF3; R4 represents H; and R5 represents C1-C6alkyl or C1-C6halogenalkyl, each one is substituted with one substituent, independently tselected from hydroxy, C1-C6alkoxy, C1-C6alkylthio, C1-C6alkysulphinyl, C1-C6alkylsulfonyl, C2-C7alkylaminocarbonyl, C2-C7halogenalkylaminocarbonyl. Compounds of formula 1 are intended for combating insects-pests and for protection of animals from invertebrate parasitic pests.

EFFECT: naphthaleneisoxazoline derivatives for combating invertebrate parasitic pests.

31 cl, 18 tbl, 22 ex

FIELD: chemistry.

SUBSTANCE: invention relates to agriculture. Herbicidal composition contains clethodim in form of trialkylamine salt, which contains in one of alkyl radials not fewer than eight atoms of carbon, and tribenuron-methyl in form of trialkylamine salt, which contains in one of alkyl radials not fewer than eight atoms of carbon. Composition contains surface-active substance of nonionic type. Herbicidal composition is obtained by mixing components with the following components ratio, wt %: clethodim 15-40, tribenuron-methyl 5-30, trialkulamine, which contains in one of alkyl radials not fewer than eight atoms of carbon 15-60, surface-active substance of nonionic type 20-40, aromatic solvent 5-15.

EFFECT: invention makes it possible to increase efficiency of composition in crops of sunflower, resistant to tribenuron-methyl, with respect to monocotyledonous and dicotyledonous weed plants.

10 cl, 7 ex, 2 tbl

FIELD: chemistry.

SUBSTANCE: invention relates to agriculture. Fungicidal preparation includes carbendazim in form of modification: salt of carbendazim with organic or mineral acid and auxiliary components with the following ratio, wt %: carbendazim salt with mineral or organic acid 20-65, surface-active substance 2-7.3, filler 0.5-5, film-former 0.3-2, hard water softener 0-1, antifreeze 0-20, dye 0-1, diluent - water the remaining part. As organic acid applied is alkylbenzolsulfoacid of formula C8-18H17-37C6H4SO3H or p-toluenesulfonic acid, and as mineral acid - hydrochloric or phosphoric, or boric acid.

EFFECT: invention makes it possible to reduce norms of active substance consumption with preservation of fungicidal activity.

3 cl, 20 ex, 3 tbl

FIELD: agriculture.

SUBSTANCE: invention relates to agriculture. The presowing treatment of cereal seeds is carried out with 6-methyl-4-(2-pyridylsulfanil)-1,3-dihidrofuror-3,4-c]pyridin-3, exhibiting growth-regulating activity in a dose of 0.2-0.6 g/t of seeds at a consumption rate of operating fluid 10 l/t of seeds.

EFFECT: invention enables to improve productivity.

6 tbl, 7 ex

FIELD: chemistry.

SUBSTANCE: invention relates to novel compounds of general formula , where R is CH3(CH3)CHCH2CH2-, CH3CH=CHCH2-, , which have acaricidal activity. The invention also relates to a method for production of said compounds, which involves reacting corresponding alcohols with quaternary terpenyl ammonium salts, such as N-(2,7-dimethyl-2,7-octadien-1-yl)allyldiethylammonium bromide, N-(2,7-dimethyl-2,7-octadien-1-yl)allylpiperidinium bromide and N-(2,7-dimethyl-2,7-octadien-1-yl)methyldiethylammonium iodide, in the presence of NaOH.

EFFECT: disclosed compounds can be used as acaricidal preparations in veterinary in case of sarcoptic mange and common scab in pets and farm animals.

2 cl, 2 tbl, 5 ex

FIELD: chemistry.

SUBSTANCE: present invention provides the compound 1-(1-ethyl-4-(3-(2-methoxyethoxy)-2-methyl-4-(methylsulphonyl)benzoyl)-1H-pyrazol-5-yloxy)ethyl methyl carbonate or a salt thereof. The invention relates to a method of producing said compound; a herbicide containing said compound as an active ingredient; and a weed control method or a method of inhibiting weed growth, which involves applying a herbicide-effective amount of said compound on weeds or place where weeds grow.

EFFECT: compound demonstrates excellent herbicidal action and has a wide range of application, including agricultural fields and non-agricultural fields, and various methods of application, which include treatment of soil and leaves.

4 cl, 17 tbl, 17 cl

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a new anti-nematode drug representing triphenyl-(3,5-di-tret-butyl-4-hydroxybenzyl)phosphonium bromide which may be used in veterinary science.

EFFECT: what is presented is the new antihelmintic with low toxicity and high therapeutic efficacy in a low single therapeutic dose of 0,01 g/kg of animal's body weight.

1 cl, 5 tbl, 3 ex

FIELD: chemistry.

SUBSTANCE: invention relates to biocides. The synergetic antimicrobial composition contains glyphosate and diiodomethyl-para-tolyl sulphone. A coating composition contains said synergetic antimicrobial composition. A dry film is obtained from said coating composition by drying or holding in air.

EFFECT: inhibiting growth or controlling growth of microorganisms in construction material when said synergetic antimicrobial composition is added.

7 cl

FIELD: chemistry.

SUBSTANCE: invention relates to biocides. The synergetic antimicrobial composition contains glyphosate or zinc salt thereof and 3-iodo-2-propynyl butylcarbamate. A coating composition contains said synergetic antimicrobial composition. A dry film is obtained from said coating composition. A zinc salt of glyphosate is obtained by: (a) obtaining an aqueous glyphosate solution, (b) mixing said aqueous glyphosate solution with an aqueous solution of an inorganic zinc salt. Said mixing is carried out while keeping pH of the mixture not higher than 5.

EFFECT: invention increases efficiency.

8 cl

FIELD: chemistry.

SUBSTANCE: invention relates to agriculture. Presowing treatment of rice seeds is carried out with 4-[4-(tert-butyl)phenyl sulphanyl]-6-methyl-1,3-dihydrofuro [3,4-c]pyridin-3-none, which has growth-regulating activity in a dose of 0.1-0.3 g/t seeds with working liquid consumption of 10 l/t seeds.

EFFECT: invention increases rice yield.

2 tbl, 3 ex

FIELD: agriculture.

SUBSTANCE: invention relates to agriculture. Synergistic fungicidal combination of biologically active substances comprises a carboxamide of formula (I) where R1 is fluorine, R2 is chlorine, R3 is chlorine, R6 is methyl, R7 is difluoromethyl, R8 is hydrogen, and at least one biologically active substance selected from the group consisting of cyproconazole, metconazole, fenpropimorph and metrafenone. It is used for controlling unwanted phytopathogenic fungi.

EFFECT: invention enables to improve the efficiency of processing.

2 cl, 21 tbl

FIELD: agriculture.

SUBSTANCE: invention relates to the sphere of agriculture. An agrochemical composition in the form of a suspension concentrate or a granulate dispersed in water contains the following: - from 1 to 60 wt %, at least of one reactant selected from spirotetramate, tebuconazole, tiacloprid, fluopicolide and imidacloprid, - from 1 to 50 wt%, at least one penetration intensifier, which is ethoxylate of rapeseed, corn, palm kernel or almond oil , - from 1 to 20 wt%, at least one non-ionic and/or at least one anionic surfactant and - from 0.1 to 25 wt% of additives selected from a group containing defoaming agents, preservatives, antioxidants, additives to improve spread, dyes and/or thickeners. The composition is used to control pests, phytopathogenic fungi.

EFFECT: invention will make it possible to increase stability and activity of a composition.

6 cl, 8 tbl

FIELD: chemistry.

SUBSTANCE: invention relates to compositions and methods used in ectoparasite control in domestic animals. The local composition for point deposition on a domestic animal for ectoparasite control contains an amount of indoxacarb which is sufficient for exterminating ectoparasites and a veterinary-acceptable carrier. Concentration of indoxacarb is equal to at least 100 g/l; the veterinary-acceptable carrier contains a crystallisation inhibitor and a solvent selected from a group consisting of glycol ether and alkyl acetate. An effective amount of the composition is applied locally to a bounded region having surface area less than or equal to 10% of the total surface area of the domestic animal. The composition for local deposition on a domestic animal in order to fight invasion by ectoparasites contains the following in wt %: 15-25 indoxacarb, 15-25 triacetin, 10-40 ethylacetoacetate or dipropylene glycol monomethyl ether and isopropyl alcohol to bring the composition to 100%.

EFFECT: invention enables one to implement said applications.

39 cl, 5 tbl, 5 ex

FIELD: chemistry.

SUBSTANCE: invention relates to a synergetic insecticide containing active substances in form of a compound of general formula where E denotes NO2 or CN, R denotes thiazolyl-methyl or pyridyl-methyl, substituted with a halogen, A denotes hydrogen, Z denotes an alkylamino group with 1-4 carbon atoms or A and Z together with atoms with which they are bonded form thiazolidine, imidazolidine, hexahydro-1,3,5-triazine in which nitrogen atoms in positions 3 and 5 are substituted with two alkyl groups with 1-4 carbon atoms in the alkyl group, a 6-member saturated heterocyclic fragment which additionally contains oxygen and a N-alkyl heterogroup, where the alkyl in the N-alkyl group contains 1-4 carbon atoms, and a fungicidal active substance selected from a group comprising difenoconazole, triadimefon, fluquinconazole, fenpropimorph, procymidone, dichlofluanide, captan, anilazine, maneb, mancozeb, benomyl and sulphur.

EFFECT: high efficiency of the insecticide.

3 cl, 5 ex, 3 tbl

FIELD: chemistry.

SUBSTANCE: invention relates to agriculture. The composition for controlling plant diseases and damages to plants by insects contains active components (RS)-1-methyl-2-nitro-3-(tetrahydro-3-furylmethyl) guanidine (INN: dinotefuran) and at least one fungicidal compound selected from a group comprising the following substances: 2',4-dichloro-α,α,α-trifluoro-4'-nitro-m-toluene sulphone anilide (INN: flusulphamide), 3-hydroxy-5-methylisoxazole (INN: hymexazol) and (RS)-2-(4-fluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-3-(trimethylsilyl)propan-2-ol (INN: simeconazole).The pest control composition is applied into the soil, plant seeds, stored cereals, stored legume fruits, stored fruits, stored vegetables, silos, stored flowers or wood for export/import.

EFFECT: invention lowers toxicity of the composition.

12 cl, 7 tbl, 9 ex

FIELD: agriculture.

SUBSTANCE: oil suspension concentrate is described, which contains a) one or more herbicide biologically active substances from the group thienylsulfonamides and b) a number of organic solvents, at least one of which is a polar aprotonic solvent from the group C1-C18-alkylene carbonats. Oil suspension concentrate is suitable for plant protection.

EFFECT: obtaining the preparation which has high chemical and physical stability.

5 cl, 1 tbl, 5 ex

FIELD: medicine.

SUBSTANCE: there are described synergistic fungicidal combinations of biologically active substances which contain one carboxamide of general formula (I) , (group 1) where A, R1, R2 and R3 have values presented in the patent claim, and a biologically active substance chosen from compound groups specified in the patent claim (2) - (17) have. There is described application of said agent for undesired plant pathogenic fungi control.

EFFECT: extended range of the agents for undesired plant pathogenic fungi control.

8 cl, 13 tbl, 12 ex

FIELD: agriculture.

SUBSTANCE: proposed synergetic effect herbicide compound contains efficient amounts of components (A) and (B), with (A) standing for a single or multiple herbicide substance(s) with general formula as well as salts thereof and (B) standing for a single or multiple herbicide substance(s) that are used for selective control of monocotyledonous and/or dicotyledonous weeds with monocotyledonous cultivated plants and belong to the compounds group including: (B1) flucarbazon, (B2) BAY MKH 6561 (procarbazon), (B3) florasulam, (B4) halosulphuron, (B5) tritosulphuron, (B6) pikolinafen, (B7) cinidon-ethyl, (B8) mezotrion, (B9) metosulam, (B10) cloryralid, (B11) flufenacet, (B12) flumetsulam, (B13) flupoxam, (B14) prosulphocarb, (B15) flutramon, (B16) aclonifen, (B17) hexazinon, (B18) asulam, (B19) diuron, (B20) amertin, (B21) izoxaflutol, (B22) amicarbazon, (B23) trifloxisulphuron; excluded are the herbicide compounds whose (A) component is one or several herbicide substances belonging to the (I) general formula group as well as salts thereof where R1 is (C1-C8)-alkyl, (C3-C4)-alkenyl or (C3-C4)-alkinyl, R2 is CH2NHSO2CH3, R3 is metoxi and Z is CH, and (B) component is one or several herbicide substances belonging to the compounds group including (B9), (B13), (B14) and (B15).

EFFECT: quantitative minimisation of specific agents application.

7 cl, 8 tbl, 4 ex

FIELD: chemistry.

SUBSTANCE: application of alcohol ethoxylates of general formula (I) , where n=6, Q represents a branched tridecyl radical, as penetrants for herbicidally active compounds from the group of the triazolinones is set forth. The aforecited group of the triazolinones is described by formula (II) , where R1 represents an alkyl radical with number of carbon atoms up to 6, R2 represents an alkoxy group with number of carbon atoms up to 6 and R3 represents a phenyl substituted by alkoxycarbonyl group with number of carbon atoms up to 6 or by haloid-containing alkoxy group with number of carbon atoms up to 4. Herbicide agent containing compound of formula (I), herbicide of formula (II) from the group of the triazolinones and additives are also described as well as method of treatment with this agent of plants and their life environment.

EFFECT: herbicide penetration to plants.

8 cl, 1 tbl, 2 ex

FIELD: organic chemistry, herbicides.

SUBSTANCE: invention relates to substituted thene-3-ylsulfonylamino(thio)carbonyltriazolinones of the formula (I) and their salts wherein Q means oxygen or sulfur atom; R1 and R2 mean alkyl with 1-6 carbon atoms; R3 means hydrogen atom, halogen atom, alkyl with 1-6 carbon atoms substituted if necessary with alkoxy-group with 1-4 carbon atoms, alkoxy-group with 1-6 carbon atoms substituted if necessary with halogen atom or alkoxy-group with 1-4 carbon atoms, alkylthio-group with 1-6 carbon atoms, cycloalkyl with 3-6 carbon atoms, or aryl, aryloxy- or arylalkoxy-group, respectively, with 6 or 10 carbon atoms in aryl moiety and, in case of arylalkoxy-group, with 1-4 carbon atoms in alkyl moiety; R4 means alkyl with 1-6 carbon atoms, alkoxy-group with 1-6 carbon atoms, dialkylamino-group, respectively, with 1-4 carbon atoms in alkyl moieties, cycloalkyl with 3-6 carbon atoms, or in common with R3 it means if necessary, branched or substituted with alkyl with 1-4 carbon atoms oxaalkanediyl, thiaalkanediyl or azaalkanediyl with 3-6 carbon atoms and wherein oxa-, thia- or aza-groups can be at the beginning, at the terminal part or inside of alkanediyl group. Proposed compounds elicit the herbicide activity. Also, invention describes herbicide agent based on compounds of the formula (I).

EFFECT: valuable property of compounds, and agent.

10 cl, 23 tbl, 3 ex

FIELD: chemistry.

SUBSTANCE: invention relates to agriculture. A pesticide mixture, selected from mixtures of neonicotinoid, pyraclostrobin and metalaxyl or mixtures of neonicotinoid and pyraclostrobin in synergetically effective amounts, provided that in the case of mixtures of neonicotinoid and pyraclostrobin, the neonicotinoid is not acetamiprid or thiacloprid. Synergetically effective amounts of components of said mixture are applied in any desired sequence, simultaneously, and specifically together or separately, or consecutively, in order to improve plant health, for antifungal control or seed protection.

EFFECT: invention increases treatment efficiency.

15 cl, 2 tbl

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