Method for prevention of developing acquired microorganism resistance to disinfectants

FIELD: medicine.

SUBSTANCE: invention refers to public health, veterinary science, food processing, pharmaceutical and biotechnological productions. Disinfection objects are processed by the system of disinfectants consisting of at least two preparations, wherein at least one of the preparations is specified in a group of oxidants, namely oxygen-chlorine substances, and at least one of the preparations is specified in a group of non-oxidants, including, QACs - quaternary ammonium compounds, tertiary amines, aldehydes, guanidines. The system of disinfectants is packed within a package so that each preparation is placed separately, and each following preparation is used only after the previous preparation has been consumed completely.

EFFECT: invention provides the controlled rotation of disinfectants that prevents the developing acquired microorganism resistance.

3 ex

 

The invention relates to health, veterinary, food industry, pharmaceutical and biotech industries. The method can be used to prevent the development of microbial resistance to disinfectants, when carrying out regular health and hygiene, sanitary engineering, sanitary-veterinary and anti-epidemic measures with the use of the hard algorithm of their rotation.

The prior art method of chemical sterilization of medical instruments, including disinfection, sterilization and sterilization processing chemicals. The tools are placed for 3-4 minutes in a solution which contains ethyl alcohol, bleach, thimerosal and distilled water. Then dried through their touch to sterile filters and dipped for 5 s in a neutralizing solution dedicated, which contains hydrochloric acid, permanat potassium and distilled water (EN 94027763 A1, 20.05.1996).

The prior art method of sterilization, including the stage of processing of the products of 0.05-0.3%governmental solutions biocidal products based on clathrate Quaternary ammonium compounds with urea and the subsequent stage of the processing solution, sidegrades hydrogen peroxide with a concentration of from 2.5 to 3.5% (EN 2277935 C2, 20.06.2006).

The most is its close to the proposed technical solution is the way disinfectant after detection in the process of monitoring the resistance of microorganisms to apply disinfection tool and its replacement on the drug from another group (SANPIN 2.1.3.2630-10, Sanitary-epidemiological requirements to the organizations engaged in medical activities).

The disadvantages of these methods is the lack of rotation of disinfectants or the lack of periodicity when carrying out disinfection, and therefore, the potential risk of disease infection after ingestion of food products produced by enterprises of the food industry and public catering, increase risk of nosocomial infection in medical institutions since the development of resistance of microorganisms to the replacement of inefficient disinfectant, as well as the risk of mass mortality of farm animals associated with the inefficiency of the sanitary-veterinary regimes in cattle-breeding farms.

The technical result of the invention is to increase the efficiency of the disinfection process objects without increasing its cost.

The technical result of the proposed method is due to the fact that the objects of the disinfection process system disinfection preparations, consisting of at least two drugs, at least one of the drugs selected from the group of oxidizers, namely, oxygen, chlorine, and at least one of the drugs of choice for the Academy of Sciences of the group are not oxidizing agents including HOUR - Quaternary ammonium compounds, tertiary amines, aldehydes, guanidine, the system disinfection preparations, picked in one package so that each drug is available separately, using each of the following drugs is only after the complete consumption of the previous product. As a result of implementation of the method is controlled rotation of disinfectants, impeding the development of acquired resistance of microorganisms to disinfection drugs.

Disinfectant used for the prevention of almost all infectious diseases. The most actual problem of development of microbial resistance to disinfectants is the prevention of infections caused by, for example, S.epidermidis, E.coli, P.aemginosa, S.capitis, S.aureus, S.haemolyticus, K.pneumomae, Citrobacter freundii, Hafnia alvei and other

Process to prevent the development of acquired resistance of microorganisms to disinfectants, as follows.

For the process of disinfection of various objects create a system of disinfectants, which consists of two or more drugs that are picked in one package. However, one of the disinfectants are selected from the group of oxidants, namely, sour is one chlorine-based tools (for example: Harmonica, Chlorine attack, Nugaal, Sulfohlorantin, Epsilon, Chloramine), other disinfection agent is chosen from the group not oxidants, which includes: H - Quaternary ammonium compounds, tertiary amines, aldehydes and guanidine (for example: Absolutel, Aquistion, Alumina, Priaulx, Central, Trimox, Alginate Deux, Wendelin).

These sanitizers are completed in one package so that each drug was posted separately. The use of each of the following drugs is only after the complete consumption of the previous product, i.e. after the first disinfection tool, placed in the upper part of the packaging, drained, open the partition between the first and second drug and start using a second drug, then the third and so on, up until the package is fully used up. The amount of each of the drugs in the package lay at the rate of not less than 1 week of work, because this period is the minimum time for the development of microorganisms resistance to disinfectants. Out of all the drugs in the carton, open and use the following packaging etc. With such consistent application of disinfectants is problema rotation, preventing the development of acquired resistance of microorganisms.

Packaging can be made of cardboard in a box with compartments. During the experimental validation of the developed method revealed no effect of packing material on the technical result achieved. The only condition for the choice of packaging material is the ability to withstand the weight of disinfectants during transportation, storage and use.

The proposed method to prevent the development of acquired resistance of microorganisms to disinfectants is illustrated by the following examples of implementation.

Example 1 (for comparison)

In the dressing rooms of the departments of surgical profile for disinfection of medical devices, floors, walls, pieces of furniture, including tables, chairs, couches, within 1 year used the drug for Alumina, which belongs to the group of H - Quaternary ammonium compounds. The test results revealed that the objects disinfection was found to 17% of microorganisms that are resistant to disinfection tool.

Example 2

For disinfection of objects in the bacteriological laboratories of medical institutions tested system of disinfectants, which consists of three drugs picked in one packaging, the First product is a chlorinated tool Sulfohlorantin, a second drug - Alumina on the basis of the HOUR, the third drug - Mistral from the group of tertiary amines. These drugs are picked in one package so that each drug was posted separately; the first drug is placed in the upper part of the packing, then the second product and the third drug is placed in the bottom of the packaging. In the disinfection process at first, within a week, the surface is treated first drug, namely, the oxygen - chlorine tool Sulfochlorinated to its full use. The drug is used according to the modes specified in the instructions on the drug. Below is a fragment of it.

0,1
Modes of disinfection solutions "Sulfochlorinated" when bacterial infections (excluding TB) etiology
The object disinfectionThe concentration of the solution on the drug, %Decontamination time, minThe way to handle
Surfaces in premises, rigid pieces of furniture, apparatus, appliances0,160Irrigation or wiping
Dishes without food residue30Dive
Dishes with food debris0,260Dive
Linen, not contaminated secretions0,130Soaking
Linen contaminated with secretions0,260Soaking
Toys0,130Dipping, wiping or irrigation
Sanitary-technical equipment0,260Two irrigation or twice, wiping with an interval of 15 min
ML60
Cleaning equipment0,260Soaking

At the end of the week, after the first drug is drained, open the partition between the first and second drug and the and surface disinfection are beginning to apply a second drug, namely Alumina, processing the second drug also happens during the week. The drug is used according to the modes specified in the instructions on the drug. Below is a fragment

Modes of disinfection facilities solutions "Alumina" in bacterial infections (excluding TB)
The object disinfectionThe concentration of the solution(in preparation), %Decontamination time, minThe method of disinfection
Surfaces in premises1,030Wiping
3,015

The patient-care items from metals, glass, plastics, rubbers1,060Wiping or immersion
3,030
5,015
Linen uncontaminated 1,015Soaking
1,0120
Linen contaminated with secretions3,060Soaking
5,030
1,060
Sanitary-technical equipment3,030Wiping
5,015
1,0120
Cleaning equipment3,060Soaking (immersion)
5,030

Then, after the AK full amount of the second drug, open the partition between the second and third preparation and surface disinfection put the third drug, namely Mistral.

Processing the third drug is also happening during the week. After the first pack is completely depleted, you start to use the second package, then the third, etc. Installed that before applying combinations of disinfectants on objects disinfection was found in 27% of cases, microorganisms resistant to previously used disinfectants on the basis of the HOUR or Quaternary ammonium compounds. When using our developed method is resistant to disinfectants microorganisms were not found during the whole period of observation.

The way to prevent the development of acquired resistance of microorganisms to disinfectants, characterized in that the objects of the disinfection process system disinfection preparations, consisting of at least two drugs, at least one of the drugs selected from the group of oxidizers, namely, oxygen, chlorine, and at least one of the drugs selected from the group of not oxidizing agents, including, HOUR - Quaternary ammonium compounds, tertiary amines, aldehydes, guanidine, the system of desinfektionsapparate, picked in one package so that each drug is available separately, using each of the following drugs is only after the complete consumption of the previous product with controlled rotation of disinfectants, impeding the development of acquired resistance of microorganisms.



 

Same patents:

FIELD: chemistry.

SUBSTANCE: group of inventions relates to field of biochemistry. Claimed is method of separation and purification of target protein by chromatography, in which chromatography removes or reduces content of prions (PrPSc). Realised is interaction of potentially PrPsc-contaminated sample, which contains target protein, with combined chromatographic material, which contains ligand. Ligand is selected from: positively charged N-benzyl-N-methylethanolamine ligand; negatively charged ligand of 2-(benzoylamino)butamoic acid; phenylpropyl ligand; N-hexyl ligand; 4-mercaptoethylpyridine ligand; ligand of 3-[{3-methyl-5-((tetra hydrofuran-2-ylmethyl)amino)-phenyl}amino]benzoic acid. Than buffer conditions in chromatographic conditions are created, such as, target protein binds with combined chromatographic material, and PrPsc does not bind with combined chromatographic material. Then target protein is eluted. Also claimed is fraction of pharmaceutically applicable target protein with reduced content of prion protein.

EFFECT: invention makes it possible to obtain fraction of target protein with reduced content of PrPsc from >1 to 4 lg(10) by application of single chromatographic resin.

9 cl, 3 tbl, 2 ex

FIELD: agriculture.

SUBSTANCE: invention relates to agriculture, namely to veterinary helminthology and sanitation. Under the influence of a temperature of minus 70°C with exposure from 1 to 18 hours, the cell membranes of cuticle of helminth larvae are damaged by ice crystals, as well as destruction of the internal organs and systems of the parasite occurs, which is localised in a capsule of muscle fiber of animal carcass. After exposure to low temperature of Trichinella larvae become quickly devitalised. The method does not require any additional preparing infested carcasses for neutralisation after skinning. Muscle tissue of neutralised animal carcasses can be used without limitations in feeding fur animals, pets and poultry, as well as for the technical processing, for example, for meat and bone meal tankage.

EFFECT: method provides reduction in the incidence of zoonotic disease among population, and can be used in feed production in preparation of bait or feed of raw meat infested with larvae of Trichinella in nurseries of hunting economy and in specially protected areas.

1 tbl, 3 ex

FIELD: biotechnologies.

SUBSTANCE: method is proposed to sterilise fluid nutrient media for cultivation of biomass. Preliminary double-staged heating of a flow of a fluid nutrient medium is carried out. Then the flow of the fluid nutrient medium is heated to temperature of sterilisation in the range from 130°C to 140°C by sending it via hollow electric heating elements for 2-6 sec. At the same time the fluid nutrient medium is maintained at the temperature of sterilisation of 130-134°C for 4-6 sec. or at the temperature of sterilisation of 136-140°C for 2-4 sec. Then the fluid nutrient medium is cooled.

EFFECT: method makes it possible to produce sterile nutrient media with high content of native sugars, makes it possible to exclude additional coolants, at the same time heat exchange equipment is simplified.

3 cl, 2 dwg, 2 ex

FIELD: medicine.

SUBSTANCE: method includes preparation of platelets concentrates (PC) and the irradiation with ultraviolet radiation with the wavelength from 200 nm to 280 nm (UV-C radiation) with radiation energy in the range from 0.01 to 2 J/cm2. Every dose of PC is contained in flexible, UV-permeable flat package for irradiation with the volume up to 5000 ml, filled by less than 30% of maximal capacity. The package during irradiation is moved by the way of shaking, rocking, rotating, so that content is circulating and during circulation the zones with variable thickness of layers is formed. Additionally the irradiation with UV-B radiation with radiation energy in the range from 0.3 to 5 J/cm2 is performed. The plasma content in PC is more than 20% w/w.

EFFECT: pathogenic microbes and leucocytes deactivation while the platelet function remains unaltered.

25 cl, 8 tbl, 8 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, and represents a method of hygienic antiseptic scrub-up consisting in sequential scrub-up of various hand areas by an antiseptic differing by the fact that the most dirty and hard-to-processed hands are scrubbed-up at first: finger tips, subungual space and nail wall in the following order: finger tips are processed by immersion of fingers in the skin antiseptics in the centre of a palm of the other hand and on the contrary, a palm of a right hand rubs the antiseptic over a back surface of the left hand, with changing the hands; the hands are locked, and the fingers of one hand move upwards and downwards to rub internal surfaces of the fingers and web spaces of the other hand; a ball of thumb of the left hand is enclosed between thumb and index finger of the right hand, and the ball of thumb is processed by rotations; a procedure is repeated for a wrist; the hands are changed; a palm of the other hand rubs a back surface of phalanxes of the bent fingers; the hands are changed; a palmar surface of one hand is processed by reciprocations of the other hand each of the procedures described above is repeated at least for 5 times, total antiseptic exposure is at least 1 min 30 sec.

EFFECT: invention provides a required degree of infectious safety of hands of medical personnel.

8 dwg

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine. Method contains the flowing stages: first element is installed into first chamber in endoscope case through hole into first chamber, with first chamber being transected by first cavity and second cavity; flowing medium of first cavity and second cavity in first chamber are separated by means of first element; stream of flowing medium is supplied via first channel through first element into first cavity; stream of flowing medium is supplied via second channel through first element into second cavity, first element is moved inside first chamber by supplying stream of flowing medium under pressure through first passage in first element into first chamber in order to move first element outside from said chamber, thus decreasing obstacles to stream.

EFFECT: application of claimed method will make it possible to increase rate of disinfection and increase efficiency of disinfection.

8 cl, 6 dwg

FIELD: medicine.

SUBSTANCE: group of inventions relates to field of medicine. Versions of devices have case and first tubular part, attached to case. It includes exploitation station and chamber, which is attachable to exploitation station and detachable from it, chamber is isolated from penetration of potentially polluting microorganisms when detached from exploitation system. Chamber has such form, size and orientation as to place endoscope with such orientation, with which first flexible tubular part is directed vertically downward from endoscope case. Chamber includes input for liquid supply and output for liquid removal. Exploitation station includes circulation system, containing, at least, one hydropump, which has pump output, connected with input for chamber liquid supply, when chamber is attached to exploitation station, and input of pump is connected with output for removal of chamber liquid, when chamber is connected to exploitation station, in order to carry out circulation of liquid through chamber. Source of sterilising flowing medium is connected with pump and control system is programmed in such a way as to control sterilisation procedure, by means of which pump realises circulation of liquid, containing sterilising flowing medium through chamber.

EFFECT: application of invention makes it possible to extend arsenal of devices for processing endoscopes of sectional type.

21 cl, 9 dwg

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to field of medicine, to disinfectants. Disinfectant is secondary (poly)N,N-diallylammonium trifluoroacetate (PDAATFA) and tertiary (poly)N,N-diallyl-N-methylammonium trifluoroacetate (PDAMATFA), obtained on the basis of trifluoroacetates of diallylamines (DAA) (DAA monomer itself and N,N-diallyl-N-Nmethylamine (DAMA)), polydiallylammonium salts of general formula: where R=H; R=CH3; n=114-244 (average-weight degree of polymerization); Mw=24000-55000 g/mol (average-weight molecular weight); δ=1.85 is coefficient of polydispersibility of molecular-weight distribution Mw-Mn, where Mn is average-number molecular weight, as mycobactericidal and tuberculocidal disinfectant.

EFFECT: invention ensures bacteria death within 15-30 minutes and possesses in vitro mycobactericidal and tuberculocidal activity.

3 tbl, 1 dwg

FIELD: medicine.

SUBSTANCE: invention refers to a method of sterilisation and a device for sterilisation objects by destruction of microbes with hydrogen peroxide. Method of sterilisation of an object in the reaction vessel using vapours of hydrogen peroxide as a sterilising agent comprises exposure of the inner space of the reaction vessel at a pressure of vacuum, which is lower than the equilibrium vapour pressure of hydrogen peroxide, heating the interior of the reaction vessel and the evaporator to a temperature of 30°C to 60°C, insertion of hydrogen peroxide solution into the interior of the reaction vessel through the evaporator, thermal evaporation of a solution of hydrogen peroxide in the reaction vessel during the insertion stage, sealing the inner space of the reaction vessel and holding the object in an atmosphere of hydrogen peroxide vapour and insertion of external gas into the interior of the reaction vessel to rise and maintain the pressure in the interior space prior to the predetermined value in the range from 100 to 600 Torr. Method provides effective sterilisation of object having narrow and long cavity. The steriliser includes a reaction vessel for containing the object, a vacuum pump, a reservoir of hydrogen peroxide, an evaporator, a heating device, a unit of pressure change for insertion of external gas into the reaction vessel.

EFFECT: invention provides effective sterilisation of an object.

16 cl, 7 dwg, 1 tbl, 1 ex

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to forensic pathology. A composition for recovery and preservation of human skin preparations consisting of 96° ethanol, distilled water, propylene glycol, glycerine, sodium chloride, sodium benzoate taken in a certain ratio.

EFFECT: composition improves effectiveness and quality of forensic processing.

4 dwg

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine, particularly to stabilised aqueous antimicrobial compositions. The antimicrobial composition contains 2-25 wt % of 2,2-dibrom-3-nitrilopropionamide, 5-30 wt % of an aliphatic compound containing 2 to 6 hydroxyl groups, 20-70 wt % of ethylene glycol, 2-30 wt % of water.

EFFECT: invention provides stability and low viscosity of the composition.

10 cl, 5 ex

Disinfectant // 2481126

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medical microbiology and medicine, namely to disinfection, and may be used for preparing disinfectants for disinfection of the surfaces contaminated by microorganisms, medical, sanitary and microbiological equipment. The disinfectant contains hydrogen peroxide, a water suspension of silver nanoparticles and non-ionic detergent Triton X-100 in certain amounts.

EFFECT: invention provides improved microbicidal activity on vegetative and spore forms of microorganisms at the low concentrations of its ingredients.

4 dwg, 3 ex

Disinfectant // 2481126

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medical microbiology and medicine, namely to disinfection, and may be used for preparing disinfectants for disinfection of the surfaces contaminated by microorganisms, medical, sanitary and microbiological equipment. The disinfectant contains hydrogen peroxide, a water suspension of silver nanoparticles and non-ionic detergent Triton X-100 in certain amounts.

EFFECT: invention provides improved microbicidal activity on vegetative and spore forms of microorganisms at the low concentrations of its ingredients.

4 dwg, 3 ex

FIELD: chemistry.

SUBSTANCE: group of inventions relates to disinfection and sterilisation. The acidic liquid composition used is a liquid composition which contains (a) an acidic oxidant, (b) nitric acid or salt thereof and (c) at least one carboxylic acid selected from a group consisting of monocarboxylic acids, dicarboxylic acids and tricarboxylic acids, or salt thereof. In the disinfection and sterilisation method, the acidic liquid composition contains an acidic oxidant having an excellent corrosion inhibiting property (property of preventing rust, property of inhibiting formation of an oxide film) for aluminium-based metals even in acidic conditions, without affecting the appearance or function of such metals.

EFFECT: efficiently used to disinfect or sterilise an object having a part made from aluminium-based metals.

12 cl, 20 tbl, 4 ex

FIELD: medicine.

SUBSTANCE: invention relates to disinfectants. An antiseptic disinfectant contains the film-forming preparation iodopyrone containing 6-8% of active iodine and water, contains ethanol in the following proportions, wt %: iodopyrone - 1.0-1.3 (per active iodine basis), ethanol - 20, water - the rest. The antiseptic disinfectant represents a ready-to-use preparation presented in the form of a solution or a spray.

EFFECT: invention provides the qualitative and quantitative stability of the active substance in the easily water-washable disinfectant which does not stain and has a non-irritant, prolonged effect If kept in an unopened container, it has a shelf-life of 2 years from the date of manufacture.

3 ex

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to bactericidal medication and can be applied for disinfection of livestock premises, placed in them technological equipment, implements for animal care, vehicles for transportation of animals, places where animals and other objects of veterinary supervision are concentrated. Medication includes alkyldimethylbenzylammonium chloride (ADMBAC), glutaric aldehyde, water and sodium hydroxide, taken in specified ratio. In case of specified ratio synergetic effect is observed and maximal bactericidal activity of medication, assessed by value of minimal bactericidal concentration (MBC), at which death of test-culture is observed, is reached.

EFFECT: invention ensures increase of bactericidal activity and reduction of medication toxicity with minimal content of active substances.

1 tbl, 15 ex

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to sanitation and can be applied in food, medical, veterinary, processing industry. Invention can be applied for obtaining preparations for disinfection of surfaces in premises, sanitary-technical equipment, items patient care, claimed disinfection preparation can also be applied for disinfection and pre-sterilisation cleaning of products of medical purpose, for disinfection and processing hands of medical personnel. Disinfection preparation includes quaternary ammonium compound, boric acid and represents water solution of quaternary ammonium compound, as such it contains diethyldichloropropenylammonium chloride or diethyldiallylammonium chloride, with the following ratio of initial components, wt %: said quaternary ammonium compound - 1.2 wt %, boric acid - 2.3 wt %, water - the remaining part.

EFFECT: invention ensures increase of bactericidal and fungicidal activity with reduction of concentration of working solutions of preparation, extension of action spectrum, including action on mycobacteria.

4 tbl, 1 ex

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to sanitation and can be applied in food, medical, veterinary, processing industry. Invention can be applied for obtaining preparations for disinfection of surfaces in premises, sanitary-technical equipment, items patient care, claimed disinfection preparation can also be applied for disinfection and pre-sterilisation cleaning of products of medical purpose, for disinfection and processing hands of medical personnel. Disinfection preparation includes quaternary ammonium compound, boric acid and represents water solution of quaternary ammonium compound, as such it contains diethyldichloropropenylammonium chloride or diethyldiallylammonium chloride, with the following ratio of initial components, wt %: said quaternary ammonium compound - 1.2 wt %, boric acid - 2.3 wt %, water - the remaining part.

EFFECT: invention ensures increase of bactericidal and fungicidal activity with reduction of concentration of working solutions of preparation, extension of action spectrum, including action on mycobacteria.

4 tbl, 1 ex

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine, particularly to ophthalmology, namely: to antibacterial lenses containing metals, as well as to methods for producing them. The method for producing an antibacterial lens containing a metal salt involves the stages: (a) preparation of a hard lens by a salt precursor, as well as (b) preparation of the lens produced at the stage (a) by a disperse additive specified in a group consisting of polyvinylpyrrolidone, polyvinyl alcohol, glycerol and polyethylene oxide, and a metal-containing agent specified in a group consisting of silver tetrafluoroborate, silver sulphate, zinc acetate, zinc sulphate, copper acetate, copper sulphate, silver nitrate, manganese sulphide, zinc oxide, zinc sulphide, copper sulphide, copper phosphate, silver nitrate, silver sulphate, silver iodate, silver carbonate, silver phosphate, silver sulphide, silver chloride, silver chloride, silver bromide, silver iodide and silver oxide. The other method for producing involves the stages (a) of preparation of a hard lens by a metal-containing agent, and a disperse agent, (b) preparation of the lens prepared at the stage (a) by a salt precursor. The antibacterial lens containing the metal salt is produced by said methods.

EFFECT: group of inventions provides producing the lenses with a decreased degree of opacity.

16 cl, 1 tbl

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to medicine and may be used in hospitals, polyclinics, resort institutions for high level disinfection and sterilisation. A method for preparing a disinfectant provides mixing of liquid ingredients in the form of two solutions immediately before use. One of the solutions contains, wt %: urea peroxyhydrate - 2-16; corrosion inhibitor Korantin PP - 0.5-2; chelating agent Trilon M Liquid - 0.5-2; sulphuric acid for making the pH value of the solution - 0.5-2; deionised water - the rest. The second solution contains, wt %: ethyl acetate - 20-40; acetic acid - 8-11; potassium bichromate 0.1-0.3; sodium silicate - 0.05-0.7; polyethylene oxide - 0.3-3; acetyl caprolactam - the rest. The relation of the first to second solutions makes 70:1 to 500:1.

EFFECT: group of inventions provide the high disinfecting properties of the product, anti-corrosion effect on steel, non-ferrous metals, chromium-nickel coatings; the agent has no damaging action of the objects to be treated, does not decolour cloths, does not fixes organic impurities, does not damage endoscopes and fibre optics, as well as reduces the solution concentration and exposition time on the treated objects.

3 cl, 1 tbl, 1 ex

FIELD: medicine, virology, pharmacy.

SUBSTANCE: invention relates to using derivatives of dithiocarbamate of the formula: R1R2NCS2H and oxidized forms of these compounds, in particular, their dimmers and their pharmaceutically compatible salts for preparing an agent used in treatment or prophylaxis of infection caused by RNA-containing viruses that damage respiratory tract and inducing disease. Also, invention relates to a disinfecting agent containing dithiocarbamate compound and a method for disinfection of surfaces, media and cell cultures.

EFFECT: valuable medicinal properties of compounds.

19 cl, 14 dwg, 14 ex

Up!