Method for activation of cerebral verbal functions

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to drug-free methods for activation of the cerebral verbal functions. Cerebral signals are recorded. Their duration is measured. A related verbal stimulus is established for the derived wave duration and has an effect on the patient. That is followed by measuring the duration of the next current wave through a time interval not less than the maximum duration of the used verbal stimuli, and the patient is exposed to the verbal stimulus corresponding to the current wave. According to the other version of implementing the method, the duration of the current wave is measured, and the corresponding verbal and contextually harmonised visual stimuli are set for the above duration. The patient is exposed thereto. That is followed by measuring the duration of the regular current wave through a time interval not less than the maximum duration of the used verbal stimuli, and the patient is exposed to the verbal and contextually harmonised visual stimuli corresponding to the current wave.

EFFECT: invention enables acceleration the process of verbal development in children.

1 dwg, 3 ex

 

The invention relates to medicine, namely to non-medical ways to activate voice functions of the brain and can be used to restore speech with mental retardation, rehabilitation activities of patients with organic lesions of the brain, in the various forms of Allie, dysarthria, aphasia and other speech disorders of various etiologies.

Currently, the actual search and development of new effective methods to restore speech functions. One of the promising directions of development of effective speech therapy are methods of functional treatment, including different types of sensory effects with minimal use of drugs. In order to use various types of sensory stimulation in the ways of speech therapy is functionally-specific activation of brain regions that form of speech abilities.

Known way to restore speech disorders of various origins (Zelenkova IM, Shevtsova, E.E., RF patent №2242954 for the invention "Method of recovering speech disorders of different Genesis"). This method is carried out influence on the speech of the patient individually tailored light pulses. Retisert speech of the patient by means of these pulses. Sound pulses updat the Executive serves their tactile perception. The rhythm of light and sound impulses set in the range 40-200 bits per minute and shall be checked visually by floating and/or running line of the light signal of the pendulum. The duration of each pulse is chosen in the range from 0.2 to 1 C. the Volume is in the range from 0 to 60 dB. The range of the sound pulse is 438-445 Hz. The method allows to increase the effectiveness of treatment disrupted the speech of the patient.

The disadvantage of this method is the absence of an objective criterion for selecting the individual parameters of the light and sound stimuli, which does not allow to establish the optimal parameters of the rhythm touch pulse for each patient. Another disadvantage of this method is the absence of specific stimuli, selectively activating parts of the brain, providing the organization of speech functions.

There is a method of voice rehabilitation at the touch Ahaziah in adults using the method of reference bioadaptive (Rudnev V., Prokopenko SV, Pokhabov D.V., RF application No. 93057295/14 for the invention "Method of voice rehabilitation at the touch Ahaziah in adults using the method of reference bioadaptive"). This method is used for rehabilitation of speech disorders the pathology of the cerebral cortex, and it can be used in the practice of neurology and speech therapy. The objective of the invention - creation is effectivnogo treatment of sensory afasi using in the rehabilitation process individually selected tempo rhythm of exogenous stimulation. The set task is solved by the fact that the rhythm set with light and sound stimulation with an initial frequency of 1 Hz. Then determine the best mode of the playback tempo stimulation at 1 Hz (light, sound, light) through the research phases of movement of the brush, which ostukivayut the rate of stimulation. Subsequent lessons are conducted in the optimal mode (light, sound or light) with a frequency of 1 Hz.

In this way carry out non-specific activation of brain structures at the expense of rhythmic light and sound stimulation with individually selected tempo-rhythm, where the objective criterion of optimization of rhythm are the parameters of the phase motion of the brush, otsukisama the rate of stimulation. This method does not use the specific acoustic signals directed to selective activation of the speech structures of the brain. The method is limited to only non-specific effect, which reduces the efficiency of its use in the treatment of disorders such specialized functions, like speech.

There is a method of psychological rehabilitation of children with disabilities in the development of intelligence on the basis of computer synergistic system (L. JAE, Arrest ME, krasnorutskaya EV, RF application No. 95100985/14 for the invention "Method of psychological rehabilitation of children with disabilities in Armenia the development of intelligence on the basis of computer synergistic system"). The invention relates to the field of pedagogy, in particular, speech therapy, and can be used for the rehabilitation of children with cerebral palsy, mentally retarded children, children with psychosomatic disorders, located in various rehabilitation centers and other institutions. In accordance with this method form the increasing complexity of the articulation of sounds, words, simple sentences and the corresponding meaning of the lexical structure of the avatar. Child have received information in increasing complexity, distort it by changing the degree of promiscuity of speech and "blur" the image. In the process of bringing change the degree of distortion and achieve error-free speech and understanding of the situation of the child.

In this way aimed for voice activation of brain structures using specific acoustic and visual stimuli: words, sentences, avatar. The procedure of presenting stimuli optimize, positioning sensory information increasing complexity and adjusting the degree of distortion. However, this method does not take into account the timing of the impact, which is essential for therapy of speech disorders. Thus, optimization of sensory effect in this way is insufficient that otricateljnihyj on the effectiveness of restoration actions.

There is a method of correction of speech that combines different types of sensory stimulation with psychopharmacological effects (Suckers M.I., RF patent №2065736 for the invention "Method of correction of speech"). The method consists in carrying out a course of treatments ritmizovannogo speech with a frequency determined on the basis of the analysis of the electroencephalogram particular patient. The electroencephalogram identify areas of residual lesions speech and related structures, determine the main or a multiple of it the frequency of communication between the affected and intact structures and take her by the code. On its basis form along with sound and light pulses, which affect the patient during the session. When the pulse frequency is determined by the parameters of the frequency patterns of EEG particular patient. Treatment support psychopharmacological agents before and/or during treatment and suggestive effect. These healing sessions are conducted in the form of group and individual lessons at least 3 times a week for 2-4 hours each session. Treatment includes 20-25 sessions. This method of correction of speech allows you to get a positive therapeutic effect in 90% of cases and to minimize the number of relapses. The method is used for stuttering, Allie, dyslalia, dysarthria, aphasia and other re is of evich violations.

The disadvantage of this method is the use for ramizali speech only frequency parameters of electroencephalogram, except for the agreement in the current time, the rhythm of the bioelectrical activity of the brain with the requirements of sensory stimuli. In addition, in this method the treatment reinforce psychopharmacological agents before and/or during treatment. This imposes restrictions on the use of this method in connection with a possible Allergy patient and other side effects.

The closest to the invention, the technical essence and the achieved result is a well-known method to normalize the physiological status (Konstantinov C.V., patent No. 2410025 for the invention "Method of normalization of the psychophysiological state"), we make a prototype In this way the signals recorded brain will agree with sensory signals. And each touch signal shape in accordance with the duration, amplitude and shape of each of the oscillation signal of the brain. Simultaneously affect patient each touch signal synchronously with each oscillation signal of his brain. The patient is instructed to pay attention to what he perceived sensory signals reflect the workings of his brain. Thus, the signal of the brain, not only the Ute as a temporal sequence of oscillations. The main parameters of the oscillations (duration, amplitude and shape) will agree with the parameters of the sensory signals, and each unique oscillation signal of the brain has a unique touch signal. In this way the touch signal with high accuracy and reflect the basic parameters of the signal of the brain. The method allows to increase the efficiency of the processes of normalization psychophysiological state after stress, emotional and intellectual strain, as well as for the treatment of functional disorders of the Central nervous system, psychosomatic diseases and effects of organic brain damage.

This method is an effective method of recovery of the functional state of the Central nervous system. The high efficiency of this method is achieved through a high degree of consistency endogenous activity of the brain with sensory signals.

The disadvantage of this method when used to restore speech functions, is the lack of specific sensory effect, selectively activating the brain structure responsible for the organization of speech. This disadvantage is selected for the prototype of way limits the effectiveness of its application in the treatment of speech disorders.

The purpose of the establishment of the proposed what about the invention is to improve the effectiveness of remedial measures, aimed at the activation of the speech functions of the brain.

This goal is achieved by the fact that in the proposed method, the activation of the speech of brain function measures the duration of the current fluctuations of the signal cord set for the duration of the oscillations corresponding to the verbal stimulus and influence them on the patient. Then measure the length of the next current fluctuations at time intervals not less maximum duration used verbal stimuli, and affect the patient's verbal stimulus corresponding to the current oscillation. In accordance with the proposed method can be registered to the duration of different types of current oscillation signals of the brain.

In another modification of the method of activation of the speech of brain function measures the duration of the current fluctuations of the signal cord set for the duration of the oscillations corresponding verbal and agreed with him within the meaning of visual stimuli and affect them on the patient. As a visual stimulus may be presented to the patient graphic text, video, image or both. Then measure the length of the next current fluctuations at time intervals not less maximum duration used verbal stimuli, and the effect of apatient verbal and agreed with him within the meaning of visual stimuli, relevant to the current oscillation signal of the brain.

At the same time, source, duration, and semantic content of verbal stimulus not associated with the duration of the current oscillation signal of the brain. The number of possible durations of current fluctuations of brain signals is limited and therefore countable. In accordance with the proposed method for each duration of the current fluctuations of brain signals from the entire range of durations for the duration of the treatment set corresponding to each signal duration of its verbal stimulus is randomly selected spoken word. The patient affected by this verbal stimulus immediately after the first randomly selected current fluctuations. The duration of the next current fluctuations measured at time intervals not less maximum duration used verbal stimuli, And, if its duration will be different from the duration of the first chosen fluctuations affect the patient's new verbal stimulus, corresponding to the duration of this new current fluctuations.

For clarity, the description of the attached figure 1, illustrating the implementation of the proposed method.

It in a conditional form of the EEG. In accordance with the proposed method for each duration is lnasty current fluctuations of brain signals T 1, ...Tx...TNfrom the whole range of durations T1-TNat the time of the treatment set corresponding to each signal duration of its verbal stimulus is randomly selected spoken word. For example, for the duration of the signal T1the word "home"for the duration of the signal T2the word "forest", for the duration of the signal T3the word "river"... for the duration of the signal Txthe word "x" ...for the duration of the signal TNthe word "cat". Starting treatment affect the patient's verbal stimulus immediately after the first randomly selected current fluctuations. Let this first current oscillation is the oscillation of T1. Then immediately after oscillation T1patient affect verbal stimulus - word "house". The duration of the next current fluctuations (let it be Tx) is measured after a time interval "t0"not less maximum duration used verbal stimuli, And if the duration of the oscillations of Txwill be different from the duration of the first chosen fluctuations in T1on the patient's affected by the new verbal stimulus - word "x"corresponding to the new current oscillation Tx. And if the duration of the next current fluctuations again bude is equal to T 1then the patient is again exposed to the verbal stimulus "house" immediately after the end of each of the current fluctuations in T1. For clarity, the diagram shows "t0" the time during which the duration of the next current fluctuations is not measured is the time interval is not smaller maximum duration used verbal stimuli.

Thus, in this way make aimed verbal stimulation of those parts of the brain that are involved in the formation of speech functions. The stimulation can be performed as in acoustic form, and visual, separately and/or together. Visual stimuli can be presented in the form of image and text. It should be noted that verbal stimulation can be done both independently and on a background of non-verbal acoustic, visual and tactile stimuli. The essential point of this method activate voice functions of the brain is a high degree of congruence specific verbal stimulus and/or an equivalent in the sense of a visual stimulus with the current oscillation signal of the brain that provides an individual rhythmic impact of these incentives on the individual patient,

The consistency of verbal stimuli with the oscillation signal of the brain is in compliance with article the OIG compliance duration of the oscillation signals the brain specific verbal stimuli, and in compliance with the temporary compliance filing verbal stimulus to the time of occurrence of the corresponding oscillation signal of the brain. Temporary compliance with verbal stimulation waveforms brain automatically provides optimal rhythmic mode of action for each individual patient, which eliminates the necessity of taking into account any additional criteria for the selection of the rhythm of stimulation.

The method allows to increase the efficiency of the recovery processes of speech brain function in various forms of Allie, dysarthria, aphasia, with mental retardation, rehabilitation activities of patients with organic lesions of the brain and other speech disorders of various etiologies.

Comparative analysis of the characteristics of the prototype and the proposed method shows that the differences of the latter lie in the consistency of verbal stimuli with the oscillation signal of the brain, in strict conformity with the duration of the oscillation signals the brain specific verbal stimuli, as well as in compliance with the temporary compliance filing verbal stimulus to the time of occurrence of the corresponding oscillation signal of the brain, in the use of specialized sensory stimuli. Therefore, proposed is the range of the method corresponds to the criterion "novelty".

Comparison of proposed method with other known in the field of technical solutions allows us to conclude that it stems from them not obvious and, therefore, meets the criterion of "inventive step".

Compliance with the proposed method the criterion of "industrial applicability" is confirmed by the implementation in devices, medical equipment.

The inventive method is implemented by using a device that contains sensors of brain signals, block registration of brain signals, the transformation block brain signals in verbal and/or corresponding in meaning to the visual stimuli, the unit impact on the patient generated verbal and/or appropriate within the meaning of visual stimuli, as well as the control unit for the current settings of the oscillation signals of the brain and the control unit.

During the treatments fluctuations of brain signals recorded by the recording unit of the brain signals. In the control unit for the current parameters of the oscillations of the brain signals the fluctuations of brain signals control the current psychophysiological state of the patient. In the transformation block brain signals in verbal and/or corresponding in the sense of visual stimuli registered by the sensor oscillation signals of the brain is converted into verbal is/or corresponding in the sense of visual stimuli taking into account the duration of each oscillation signals of the brain. Then using the impact on the patient generated verbal and/or appropriate within the meaning of visual stimuli generated by incentives affect the patient. The registration of the next oscillation signal of the brain, the formation of the corresponding verbal and/or corresponding in the sense of a visual stimulus and the impact on patient this impetus carried out in a time interval not less maximum duration of verbal stimulus. This period of time, as well as the duration of treatment procedures set by the control unit.

At the Institute of Human Brain RAS (St. Petersburg) made examination of children with mental retardation, logoneurosis, dysarthria (slurred speech, alalia. All children were treated using procedures activate voice functions of the brain (ARF) in accordance with the invention. Were surveyed 19 children: 18 boys and 1 girl aged 7 to 9 years. All children undergoing procedures ARF. Sessions ARF was listening to the child's verbal stimuli, consistent with its own EEG in real-time. Listening was done in the headphones. Procedure duration was 20 min Sessions were conducted every other day. Each child was held from 5 is about 12 sessions. In a monitoring study of 20 children (15 boys and 5 girls) with the same diagnoses underwent medical treatment with speech therapy procedures without ARF.

In the field of speech to the procedures of ARF in the examined children was observed individual words and phrases. Dictionary scarce. It does not act as a communication tool. After treatment of ARF, there was an increase active vocabulary words appear as a means of communication. In General, increased vocabulary. Below are some examples of treatment using procedures ARF.

The patient D.A., 8 years old, diagnosis: logoneurosis, increased activity. Completed 10 sessions of ARF. The duration of each session was 20 minutes. On the procedures the patient was sitting quietly, eyes closed, listening. The father of the child noted improvement in speech almost immediately from the beginning of procedures, reduced stuttering. During the course of procedures ARF stuttering is almost gone. Stuttering is returned only under strong excitement. In General, the child became calmer.

The patient K.N., 7 years old, diagnosis: motor alalia, increased activity. Conducted 5 sessions. The third procedure was to behave better (wasn't afraid, less resisted, sometimes started to act up, but soon calmed down). By the end of the course of treatments the child's mother noted that he began to use more words in speech, to speak in phrases, not individual words. One hundred is easier to perform towards him requests.

The patient M.V., 9 years old, diagnosed with dysarthria. Conducted 8 sessions. The first procedures were sitting quietly fell asleep. On subsequent procedures became more active, was talkative, agile, focused more on cooperation than on listening. As the procedure began to actively use speech to Express their status, their wishes. Began to use more words. By the end of the procedure, the parents noted a significant improvement in speech and improved communication.

In the control group of children not receiving a course of treatments ARF, such changes in the speech field for the same period of time (30-40 days) was not observed. Long-term treatment of children diagnosed with mental retardation shows that significant positive changes in speech and mental development can only be observed after a 6-month course of therapeutic interventions including medication therapy speech therapy.

Thus, the use in the treatment of the treatment of ARF in combination with traditional therapy speech therapy at least 3-4 times accelerates the process of speech development of children. Hence, the proposed method for voice activation of brain function is effective therapy of speech disorders of various etiologies.

The proposed method activate voice functions on the ESD brain can be widely used in medical and rehabilitation institutions of all kinds.

1. The way to activate voice functions of the brain, including the registration of brain signals, the formation of sensory stimuli in accordance with the duration of the oscillation signals of the brain and impact on patient these sensory stimuli, characterized in that the measured duration of the current fluctuations of the signal cord set for the duration of the oscillations corresponding to the verbal stimulus, influence them on the patient, then measure the length of the next current fluctuations at time intervals not less maximum duration used verbal stimuli, and affect the patient's verbal stimulus corresponding to the current oscillation.

2. The way to activate voice functions of the brain, including the registration of brain signals, the formation of sensory stimuli in accordance with the duration of the oscillation signals of the brain and impact on patient these sensory stimuli, characterized in that the measured duration of the current fluctuations of the signal cord set for the duration of the oscillations corresponding verbal and agreed with him within the meaning of visual stimuli, affect their patient, then measure the length of the next current fluctuations at time intervals not less maximum duration used verbal tis the catch, and affect the patient's verbal and agreed with him within the meaning of visual stimuli corresponding to this current fluctuation.

3. The activation method of speech brain function according to claim 2, characterized in that as the visual stimulus used videoabout, corresponding in meaning to verbal stimulus.

4. The activation method of speech brain function according to claim 2, characterized in that as a visual stimulus using graphic text, corresponding in meaning to verbal stimulus.

5. The activation method of speech brain function according to claim 2, 3 or 4, characterized in that as the visual stimulus used videoabout and graphic text, appropriate in the sense of verbal stimulus.



 

Same patents:

FIELD: medicine; logopedia.

SUBSTANCE: audio or speech signal is distorted by directional rotary fan propeller exposure to audio or speech signal.

EFFECT: technique allows ensuring louder, more accurate and extended articulation of audio or speech signal.

1 dwg

FIELD: medicine; medical engineering.

SUBSTANCE: method involves treating sphincter muscles with air jet. To do it, the rhinopharynx is overlapped and required pressure is created in oropharyngeal cavity. Speech quality and functional state of palatofaryngeal structures is periodically controlled from occlusion degree in dynamics. Unsatisfactory speech quality and functional state control being the case, palatofaryngeal ring structures optimum degree is procured by reducing air jet supply via the rhinopharynx. The vocal apparatus has hard palatine vault-shaped base member fixable on maxillary teeth and pharyngeal part rigidly connected to it, which distal end is rigidly connected to the rhinopharyngeal obturator. The base and rhinopharyngeal obturator are made of plastic. The base is designed so that its edge turned to the soft palatine does not reach hard palatine boundary in being fitted to the oral cavity. The pharyngeal portion of the apparatus is built of wire bent as symmetric loop having the ends rigidly fixed in the base along the median line. Loop twist part is rigidly fixed in the rhinopharyngeal obturator as the distal pharyngeal part end. Lateral portions of the loop are bent in a way that pharyngeal part of the vocal apparatus passes under Passavan cushion and enters the rhinopharynx repeating the remaining free region of the hard palate when being fitted to the oral cavity.

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3 cl, 1 dwg, 1 tbl

FIELD: medicine, logopedia.

SUBSTANCE: one should carry out computer analysis of speech signal obtained with the help of a microphone from a patient due to its spectral assay by detecting bordering values of frequency range of the main tune of patient's speech and the ratio of spectral power density in frequency area being above the main tune to spectral power density in frequency area being below the main tune. Then comes logopedic training by applying computer spectral assay of the current speech signal obtained with the help of a microphone from a patient due to monitoring at on-line mode of the ratio of its spectral power density in frequency area being above the main tune to that of in frequency area being below the main tune. Moreover, due to altering the range of one's voice, a patient should perform an exercise on increasing monitored ratio till its exceeding by, at least, 2 times, against the value of the main tune to spectral power density in frequency area being below the main tune detected as a result of preliminary computer assay. Moreover, frequency range of patient's main tune varies 80-340 Hz. Logopedic training should be carried out in on-line mode to supply patient's altered speech into earphones as an acoustic image to be imitated, moreover, alteration of speech should be conducted due to simultaneous increase of spectral power density in frequency area being above the main tune and decrease of spectral power density in frequency area being below the main tune with the help of acoustic filters to provide the increase of spectral power density in frequency area being above the main tune by 1.5 times and decrease of spectral power density in frequency area being below the main tune by 1.5. The method enables to achieve stable factual alteration of patient's vocal range psychologically perceptible as suppression of patient's "dull" voice and manifestation of patient's "rich" voice.

EFFECT: higher efficiency of compensation.

4 cl, 1 dwg

FIELD: medicine.

SUBSTANCE: method involves recording spontaneous patient speech flow, selecting speech segments by applying voice no-voice principle, determining their duration, variation, standard deviation and estimating effectiveness or no effectiveness in carrying out correction. The spontaneous patient speech is recorded at least three times at the beginning of treatment course, in the middle and at the end. Hausdorff dimension of normalized vocal segment duration set is determined each time. Adjustment efficiency is estimated in the middle of the course. When being inefficient, Hausdorff dimension dynamics is determined during the first half of the course and then adequate adjustment method is selected for the second half of the course by applying the following rule. Hausdorff dimension growing, patient attention is concentrated on his speech. Hausdorff dimension falling, patient attention is drawn away from his own speech.

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The invention relates to the field of medicine

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FIELD: medicine.

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2 tbl, 2 ex

FIELD: medicine.

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EFFECT: method makes it possible to increase reliability of determination of early stage of PD.

4 cl, 9 dwg, 1 ex

FIELD: medicine.

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EFFECT: method extends arsenal of means for control over state of patient with encephalopathy in EHF therapy.

6 tbl, 3 ex

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular to field of medical and psychophysiological diagnostics. Assessment of character of motor asymmetries - determination of degree of right-handedness - left-handedness by dominance of hand and leg, as well as sensor asymmetries - determination of leading eye and ear, is performed. Also calculated is coefficient of amplitude and frequency of mu-rhythm in central parts of left and right hemisphere, as ratio of difference of maximal and minimal values to their sum. Difference between maximal and minimal values is calculated within 3-second long interval. Dominating hemisphere of motor cortex by mu-rhythm is registered at the moment of alternate clenching right and left hand fist with application of sensomotor test by scheme: "Close eyes - make right fist - open eyes - undo the fist", "Close eyes - make left fist - open eyes - then undo the fist', during standard registration of electroencephalogram.

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9 dwg, 4 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to neuroinfections. Assessment of anamnesis data, virological indices, fever reaction and spotty-papular rash appearance is carried out. EEG is additionally registered in the first three days from the moment of admission, leukocyte index of intoxication, presence of mixed hypervirus infection are determined. If hypoxy-ischemic affection of central nervous system, spotty-papular rash on the body from the first day of disease with its "additional appearance" during 5-7 days, fever to 39-40°C during first 3-5 days are present in child's anamnesis, reduction of index of main physiological rhythm less than 30%, increased paroxysmal activity in form of diffuse sharp waves and flashes of slow activity with amplitude more than 100 mcV during 3 days or at least on one of these days are detected on EEG, value of leukocyte index is 0.2-3 conv.units, mixed hyperviruses together with varicella zoster virus, virus of type 6 herpes and/or type I herpes simplex virus are detected, risk of neurological complications is predicted.

EFFECT: method makes it possible to increase reliability of predicting risk of neurological complications in case of chicken pox in children.

3 ex

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine and medical equipment, particularly to methods and apparatuses for scalp electric potential measurement. The apparatus comprises a number of sensors obtaining the initial measurement of a scalp electric potential through a hair-covering and an air contact area; a number of preamplifiers connected to one of the appropriate mentioned sensors. The contact area produces a high and variable coupling impedance of the source and the scalp. Each preamplifier contains a broadband high-impedance input and an active bias circuit generating input impedance more than 10 petaOhm over the range from 0.01 Hz to 400 Hz; a high-gain low-noise operating amplifier with the input impedance of 10 teraOhm; and a shielded feedback and bias circuit. The preamplifier is configured to have the input impedance substantially higher than the impedance produced by the source-sensor contact area. One version of the implementation of the method for scalp electric potential measurement, the preamplifier obtains the initial measurement of the scalp electric potential and forms a pre-intensified measurement of the scalp electric potential. The measurement is taken through the hair-covering and air. In the other version of the implementation of the method, an input signal of the initial scalp electric potential is obtained from the number of sensors to generate an appropriate number of channels. It is followed by the signal pre-amplification by the preamplifier with the high input impedance to form the pre-intensified measurement of the scalp electric potential. Then, a measurement mode is configured in a group containing a channel mode relative to a reference channel, a channel mode relative to a middle channel and a differential interchannel mode. Then, the pre-intensified measurement of the scalp electric potential is biased with maintaining the mentioned high input impedance; a channel gain is adjusted to differential obtaining of the channel signal. An additional stage providing the processed channel signal is suppressing radiofrequency interferences of the channel signal with maintaining adjustment of the gain and the phase; a common-mode of the channel signal is suppressed, and the band-pass channel filtration is provided. The processed channel signal is digitised to present a digital signal of the measurement of the scalp electric potential, characterising the mentioned input signal measured according to the mentioned chosen measurement mode.

EFFECT: use of the group of inventions allows more effective measurements of the scalp electric potential due to the preamplifiers, and allows reducing the need of exfoliating of the necrotic epithelial cells or application of abrasive or conducting gels.

27 cl, 11 dwg

FIELD: medicine.

SUBSTANCE: invention concerns medicine and medical technology. A patient is exposed to electrical stimulation generated by the 'simpaticor-01' apparatus. A one-element electrode is placed in a projection of cervical ganglia, while a multiple-element electrode - on a patient's neck. The exposure to the field is paused. A convulsive readiness threshold is assessed. Neurometabolic preparation dosage is specified in accordance with age, while anticolvulsants are dosed as per manufacturer's recommendations. Amplitude, frequency and length of the current pulse field, length of exposure and pauses are specified individually for each patient so that in the process of treatment and later on, the convulsive readiness threshold tends to decrease in the form of reducing a number of paroxysmal sharp and slow waves, as well as elimination of epileptoid activity.

EFFECT: method provides higher clinical effectiveness ensured by combining drug-induced therapy with electrical stimulation of the vegetative nervous system.

7 dwg, 1 tbl, 1 ex

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to oncologic neurosurgery, neurology and functional diagnostics. Electroencephalographic (EEG) examination is carried out. Power of delta-range waves in parietal regions is estimated on EEG. In case of simultaneous increase of power in left parietal region above 80 mcV2 and in right region above 85 mcV2, malignant form of growth of neuroepithelial tumour of III ventricle is diagnosed.

EFFECT: method extends arsenal of means for diagnosing type of growth of neuroepithelial tumours of III brain ventricle.

1 tbl, 2 ex

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to oncologic neurosurgery, neurology and functional diagnostics. Estimation of clinical status and neurovisualisation data and EEG examination are carried out in preoperative period. Depending on anatomical-topographical and histological version of tumour, as well as detected clinical-EEG complex of symptoms risk of development of complications in early postoperative period in patients after ablation of tumours of basal-diencephalic localisation is predicted.

EFFECT: method extends arsenal of means for predicting development of complications in early postoperative period in patients with different anatomical-topographical versions of tumours of basal-diencephalic localisation.

3 ex

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to oncologic neurosurgery, neurology and functional diagnostics. Electroencephalographic (EEG) examination is performed. Coherent connections of brain regions, intensity of EEG rhythms in alpha-, beta- and theta- ranges are determined. Taking into account obtained EEG data and in dependence with localisation of tumour position in basal-diencephalic region, degree of functional activity disorder is determined.

EFFECT: method extends arsenal of means for estimation of degree of disorder of cerebral functional activity in patients with tumours of basal-diencephalic region.

1 tbl, 3 ex

FIELD: medicine, neurology, psychopathology, neurosurgery, neurophysiology, experimental neurobiology.

SUBSTANCE: one should simultaneously register electroencephalogram (EEG) to detect the level of constant potential (LCP). At LCP negativization and increased EEG power one should detect depolarizational activation of neurons and enhanced metabolism. At LCP negativization and decreased EEG power - depolarized inhibition of neurons and metabolism suppression. At LCP positivation and increased EEG power - either repolarized or hyperpolarized activation of neurons and enhanced metabolism. At LCP positivation and decreased EEG power - hyperpolarized suppression of neurons and decreased metabolism of nervous tissue. The method enables to correctly detect therapeutic tactics due to simultaneous LCP and EEG registration that enables to differentiate transition from one functional and metabolic state into another.

EFFECT: higher accuracy of diagnostics.

5 dwg, 1 ex, 1 tbl

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