Skin care composition

FIELD: medicine.

SUBSTANCE: invention refers to cosmetic industry and represents a skin care composition containing at least one polyurethane prepared by a reaction of one or more water-insoluble, water-nondispersible polyurethane pre-polymers with isocyanate functional groups A) with one or more compounds B containing aminofunctional groups specified in primary and/or secondary amines, and/or diamines and additives.

EFFECT: invention provides creating the skin care composition which forms a nonadhesive and oil-free protective layer after distribution in skin.

11 cl, 5 ex

 

The present invention relates to the nourishing compositions for application to the skin containing certain polyurethanes, as well as the use of these polyurethanes for the manufacture of products for skin care.

Product for skin care is a cosmetic composition for application to the skin, such as on the face and/or other parts of the body. Product for skin care is, in particular, to protect against skin changes, such as aging, drying, and similar processes. Caring for skin products must restore and maintain the skin in its normal physiological state. Layers of the epidermis occur when the damage receive support in relation to their natural ability to regenerate, that is, the upper layers of the epidermis moisturized and protected. In addition, should recover the properties associated with the permeability of the skin, and should be supported by the regeneration of the skin. In addition, the product, caring for skin, after use, must be left to creamusume soft.

A large part of the population (about 20%) suffers from dry skin. This subject, first of all, people who often take a bath or shower, older people, infants and young children, diabetics, etc. Dry skin depends on external factors such as climate, VL is of the environment, the use of soap, stay under the action of UV radiation, etc. and also from internal factors, such as, for example, dermatological diseases (atopic dermatitis, psoriasis, ichthyosis, diabetes), and skin aging. Dry skin entails, first of all, change the appearance of the skin. Roughness, flakiness, dullness, lack of elasticity, etc. can damage the well-being susceptible to this people. Dry skin may be due to lack of factors to retain moisture, such as, for example, urea, epidermal lipids and amino acids. The result is a decrease in natural capability of binding water. Damage to the barrier function, and increased transepidermal water loss.

To reduce/slow the loss of moisture is used, on the one hand, hydrophilic regulators humidity (so-called water-retaining substance) such as, for example, glycerol, and, on the other hand, the hydrophobic protective barrier components (hydrophobic lipids) such as, for example, mineral oil, lanolin, vaseline, etc. Hydrophilic humidity regulators have the ability to attract moisture in the stratum corneum of the skin Stratum Corneum. Using hydrophobic lipids formed inert closing layer which reduces transepidermal moisture loss.

The above two fur the mechanism of reducing/slowing down the loss of moisture have shortcomings well-known specialist. Highest applied concentration of hydrophilic regulators humidity in a cosmetic product after application on the skin to leave it feeling sticky skin. The hydrophobic lipid forms an oily film, which can be unpleasant for the user.

The use of polyurethanes in cosmetic compositions already described. In the European patent EP 1352642 describes application solubilizing anionic polyurethane, preferably containing 2,2-hydroxymethylcytosine carboxylic acid. Preferably used a mixture of anionic polyurethanes with polyacrylates. The nature of the polyurethanes used in the examples is unclear. Similarly, in Japanese patents JP 2005200320 and JP 2006062995 describes the use of a combination of polyacrylates and polyurethanes as film-forming substances which exhibit a shrinkage of at least 20%. In the international application WO 2002010243 proposed the use of urethanes in the cosmetic field. Obtaining prepolymer occurs with the use of complex sulfapyridine. In the international application WO 02070577 the use of anionic polyurethanes for the manufacture of compositions for skin care and makeup. Specific examples of cosmetic compositions are not disclosed. Also not available compositions for skin care.

Central to the E. of the present invention primarily have the task to provide a composition for skin care, which after distribution on the skin forms a pleasant, non-sticky and non-greasy protective film.

In an unexpected way, this task is solved by the use of polyurethane or it preferably water dispersion, the polyurethane can be obtained by reacting one or more water-insoluble, are not able to dispergirujutsja in water polyurethane prepolymers A)containing isocyanate functional groups, at least one or more compounds containing amino groups, such as primary or secondary diamine which contains at least one ionogenic or ionic group and its salts.

Therefore, this invention provides a composition for skin care containing at least one polyurethane, which can be obtained by the interaction of one or more insoluble in water, unable to dispergirujutsja in water polyurethane prepolymers with isocyanate functional groups (A) with one or more compounds containing amino groups.

In addition, this invention provides a composition for skin care containing at least one polyurethane, which can be obtained by the interaction of one or more polyurethane prepolymers with isocyanate group and A), mostly not contain any ionic or ionogenic groups, with one or more compounds containing amino groups.

In the framework of this invention, the term "insoluble in water, unable to dispergirujutsja in water polyurethane prepolymer" means first of all that the solubility of the prepolymer used according to the invention, at 23°C is less than 10 g/liter, more preferably less than 5 g/liter, and this prepolymer at 23°C does not give resistant to the deposition of a dispersion in water, in particular, in deionized water. In other words, this prepolymer is deposited when trying dispersing it in water.

Preferably the polyurethane prepolymer (A)used according to the invention, contains terminal isocyanate groups, i.e., these isocyanate groups are at the ends of the chains of the prepolymer. Especially preferably the ends of the chains of the polymer are isocyanate groups.

In addition, the polyurethane prepolymer (A)used according to the invention, preferably mainly contains no ionic or ionogenic (capable of forming ionic groups) groups, that is, it is advantageous if the content of ionic and ionogenic groups is less than 15 milliequivalents per 100 g of the polyurethane prepolymer (A), preferably less than 5 milliequivalents, especially pre is respectfully less than one milliequivalent and most preferably less than 0.1 milliequivalent per 100 g of the polyurethane prepolymer (A).

Compounds with amino groups) is preferably selected from primary and/or secondary amines and/or diamines. In particular, compounds with amino groups) include at least one diamine. Compounds with amino groups) is preferably selected from compounds with amino groups B2), which contain ionic or ionogenic groups, and compounds with amino groups B1)that do not contain ionic or ionogenic groups.

In a particularly preferred embodiment of the invention compounds with amino groups) include at least one connection with the amine groups B2), which contain ionic and/or ionic (ion-forming groups. Especially preferably as ionic and/or ionogenic groups used sulphonate or sulfonylurea group, more preferably a group of the sulfonate sodium.

In another preferred embodiment of the invention compounds with amino groups) include compounds with amino groups B2), which contain ionic and/or ionogenic groups, and compounds with amino groups B1)that do not contain ionic or ionogenic groups.

Thus, in this invention, the polyurethanes are polymeric compounds which contain at least two, preferably at least three repeating structural units, with the holding urethane groups:

. According to the invention also include such polyurethanes, which, due to production reasons also contain recurring structural units containing urea groups:such as those that are formed, in particular, the interaction of a prepolymer with terminal isocyanate groups of a) compounds with amino groups).

Compositions for skin care according to the invention preferably represent containing water, i.e. water compositions in which the polyurethane is dispersed, that is, it is present mainly in the dissolved form. Water, along with others present, if desired, the liquid media, such as, for example, solvents, constitutes the major part (>50 wt%.) dispersing medium, in terms of the total amount of liquid dispersing media in the cosmetic compositions according to the invention, and optionally also the only liquid dispersing medium.

Compositions for skin care according to the invention preferably have a content of volatile organic compounds (VOCS)which is less than 80 wt. -%, more preferably at least 55 wt. -%, even more preferably less than 40 wt. -%, in terms of the composition for skin care.

Aqueous dispersion of polyurethane used is La obtain compositions for skin care according to the invention, preferably have a content of volatile organic compounds (VOC), less than 10 wt. -%, more preferably less than 3 wt. -%, even more preferably less than 1 wt. -%, in terms of the water dispersion of polyurethane.

Determination of volatile organic compounds (VOCS) in the framework of the present invention is, in particular, by means of gas chromatographic analysis.

Polyurethane prepolymers with isocyanate groups, insoluble in water and incapable of dispergirujutsja in water, which are used according to the invention, generally do not contain any ionic or ionogenic groups. The insolubility in water or absent dispersibility in water refers to deionized water without the addition of surfactants. In the context of this invention means that the proportion of ionic and/or ionogenic (forming ions) groups, such as anionic groups such as carboxylate or sulfonate, or cationic groups is less than 15 milliequivalents per 100 g of the polyurethane prepolymer (A), preferably less than 5 milliequivalents, particularly preferably less than one milliequivalent and most preferably less than 0.1 milliequivalent per 100 g of the polyurethane prepolymer (A).

In the case of acidic ionic and/or ionogenic groups, it is advantageous if the acid is th number of the prepolymer is less than 30 mg KOH/g of prepolymer, preferably less than 10 g KOH/g of prepolymer. The acid number indicates the mass of potassium hydroxide in mg which is required to neutralize 1 g of the sample under study (measurement according to DIN EN ISO 211). Neutralized acid, and, consequently, the corresponding salt is naturally not have the acid number or have a low acid number. In this case, according to the invention the acid number refers to the corresponding free acids.

The prepolymers (A), which is used to obtain a polyurethane, preferably can be obtained by reacting one or more polyols selected from the group consisting of simple polyether polyols, polycarbonatediol, easy polyester-polycarbonatediol and/or complex polyether polyols and polyisocyanates, as explained in more detail below.

Therefore, the polyurethane contained in the compositions for skin care according to the invention, due to the presence of the prepolymer (A) preferably contain at least one recurring fragment, which is selected from the group consisting of the sequences polyether, polycarbonate, simple politicallycorrect and complex polyester. According to the invention above all, this means that the polyurethanes contain recurring structural is denizi, including the group of ester and/or carbonate groups or ester groups. These polycarbonates may contain, for example, only sequences of simple esters, or solely of a sequence of polycarbonates, or solely of a sequence of polyesters. However, they can also contain sequences as polyethers, and polycarbonates, such as those formed for receiving polycarbonatediol using simple polyetherdiols, as described in more detail below. They can also contain sequences of simple politicallycorrect, which are obtained by applying a simple politicalinternational, as hereinafter described in more detail.

Particularly preferred polyurethanes are obtained using simple polymer of polyether polyols and/or polymer polycarbonatediol, and/or simple politicalinternational, or complex polyether polyols, which respectively have srednekamennogo molecular weight, preferably approximately from approximately 400 to 6000 g/mol (hereinafter, the molecular weight determined using gel permeation chromatography relative to standard polystyrene in tetrahydrofuran at 23°C). Their use in obtaining polyure the Ana or polyurethane prepolymer due to interaction with polyisocyanates leads to the formation of the polyurethane corresponding sequences polyether and/or polycarbonate, and/or simple politicallycorrect, or sequences of complex polyester having an appropriate molecular weight of these sequences. Especially preferred according to the invention are polyurethanes which are derived from polymeric simple polyetherdiols and/or polymeric polycarbonatediol, and/or simple politicalinternational, or complex polyether polyols linear structure.

The polyurethanes according to the invention preferably are linear molecules, but can also be branched, which is less preferred.

Srednekislye molecular weight of the polyurethane, preferably used according to the invention is, for example, from about 1000 to 200,000, preferably from 5000 to 150,000.

The polyurethane contained in the compositions for skin care according to the invention, are added to the above compositions, primarily in the form of aqueous dispersions.

Preferred polyurethanes to be used according to the invention, or respectively the dispersion of polyurethanes, are obtained due to the fact that

A) get the prepolymers with isocyanate groups of:

A1) organic polyisocyanates,

A2) polymeric polyols, preferably with srednekamennogo molecular weight of from 400 to 8000 g/mol (there is further data on the molecular weight determined using gel permeation chromatography with respect to the standard polystyrene in tetrahydrofuran at 23°C), more preferably from 400 to 6000 g/mol and particularly preferably from 600 to 3000 g/mol, and having functionality for HE-groups preferably from 1.5 to 6, more preferably from 1.8 to 3, particularly preferably from 1.9 to 2.1,

A3) optionally compounds with hydroxyl functional groups with molecular weight of preferably from 62 to 399 g/mol and

A4) optionally, nonionic means giving hydrophilicity, and

B) then their free NCO-groups are completely or partially interact with one or more compounds with amino groups)such as primary and/or secondary amines and/or diamines.

The polyurethanes used according to the invention, is dispersed in water, preferably before, during or after carrying out stage B).

Especially preferably at the stage B) is carried out interaction with one or more diamines with extension chain. In addition can be added monofunctional amines as agents of an open circuit for regulating molecular weight.

As component C) may apply, in particular, amines that do not contain ionic or ionogenic groups such as anionic groups, which imparts hydrophilicity (hereinafter component B1)), and it is also possible to use amines which content is t ion or ionic, such as, first of all, anionic groups, which imparts hydrophilicity (hereinafter component B2)).

Preferably on stage) the conversion of the prepolymer is introduced into the reaction mixture of the component (B1) and the component B2). Through the use of component B1) can be obtained high molar mass, without the viscosity of previously obtained prepolymer with isocyanate groups had grown to such an extent that would prevent the processing. Using a combination of components B1) and B2) may establish an optimal balance between hydrophilicity and chain length, and, therefore, a pleasant feeling on the skin.

The polyurethanes used according to the invention, preferably contain anionic group, preferably a sulphonate group. These anionic groups are introduced into the polyurethanes used according to the invention, by means of the amine component B2), reacts on stage). The polyurethanes used according to the invention, optionally additionally contain nonionic components to enhance hydrophilicity. Especially preferably the polyurethanes used according to the invention, to increase hydrophilicity contains exclusively sulphonate groups which are introduced into the polyurethane through the corresponding diamine as component B2).

In order to achieve a good camera is lnasty to the deposition, srednesemennyh particle size specific polyurethane dispersions preferably lies in the region of less than 750 nm, particularly preferably less than 500 nm, as determined by laser correlation spectroscopy (LCS) after dilution with deionized water (instrument: Malvern Zetasizer 1000 firms Malvern Inst. Limited).

The solids content of polyurethane dispersion, which is preferably used for the manufacture of a composition for skin care according to the invention is generally from 10 to 70, preferably from 30 to 65, particularly preferably from 40 to 60% of the mass. The solids content is determined by heating a weighed sample at 125°C to a constant weight. When reaching a constant weight by re-weighting is calculated solids content in the sample.

Preferably these dispersion of a polyurethane containing unbound organic amines in amounts less than 5 wt. -%, especially preferably less than 0.2 wt. -%, in terms of the weight of the dispersion. The content in compositions for skin care, respectively, is even lower.

Suitable polyisocyanates as component A1) are primarily well-known specialist aliphatic, aromatic or cycloaliphatic polyisocyanates having a functionality NCO-groups and more and is equal to 2.

Examples of such suitable polyisocyanates are 1,4-butylenediamine, 1,6-hexamethylenediisocyanate (HDI), isophoronediisocyanate (IPDI), 2,2,4 and/or 2,4,4-trimethylhexamethylenediamine, the isomeric bis(4,4'-isocyanatophenyl)methanes or mixtures thereof with any content of isomers, 1,4-cyclohexanedimethanol, 4-isocyanatomethyl-1,8-octadienal (nonnational), 1,4-delete the entry, 2,4-and/or 2,6-tolylenediisocyanate, 1,5-naphthylenediisocyanate, 2,2'- and/or 2,4'-and/or 4,4'-diphenylmethanediisocyanate, 1,3 - and/or 1,4-bis(2-isocyanatopropyl-2-yl)benzene (TMXDI), 1,3-bis(isocyanatomethyl)benzene (XDI), and alkyl-2,6-diisocyanatohexane (lizenzierte)containing alkyl group of 1 to 8 carbon atoms.

In addition to the above polyisocyanates, in part may also be used modified diisocyanates, which have the functionality ≥2 containing uretdione, which, urethane, allophanate, biuret, iminoimidazolidine or oxidization patterns, as well as mixtures of them.

Preferably it is about the polyisocyanates or mixtures of polyisocyanates of the above type with isocyanate groups, related exclusively to aliphatic or cycloaliphatic fragments, or their mixtures, as well as the average functionality of the mixture at NCO-groups from 2 to 4, preferably from 2 to 26, and particularly preferably from 2 to 2.4, highly preferably 2.

Particularly preferably A1) are used hexamethylenediisocyanate, isophoronediisocyanate or the isomeric bis(4,4'-isocyanatophenyl)methanes and mixtures of these diisocyanates.

In A2) are polymeric polyols with srednekamennogo molecular mass Mnpreferably from 400 to 8000 g/mol, more preferably from 400 to 6000 g/mol and particularly preferably from 600 to 3000 g/mol. Preferably they have the functionality HE-groups is from 1.5 to 6, particularly preferably from 1.8 to 3, most preferably from 1.9 to 2.1.

The expression "polymer" polyols in this case denotes, in particular, that the above polyols contain at least two, more preferably at least three are related to each other repeating structural units.

Such polymer polyols are known in the technology of polyurethane varnishes complex polyether polyols polyacrylonitrile, poliuretanoviy, polycarbonatediol, simple polyether polyols complex politicalization, prioritypriority, complex prioritypriority, simple prioritypriority, polyuretaanipaksuntajat and the location for the complex. They can be used in A2) separately or in any smese is with each other.

Preferably the complex polyether polyols are known polycondensate from di-, and optionally tri - and tetraols, as well as di-, and optionally tri - and tetracosanoic acids or hydroxycarbonic acids or lactones. Instead of free polycarboxylic acids to obtain polyesters can also be used the corresponding anhydrides of polycarboxylic acids or the corresponding esters of polycarboxylic acids and lower alcohols.

Examples of suitable diols are ethylene glycol, butyleneglycol, dietilen glycol, triethylene glycol, polyalkylene glycols such as polyethylene glycol, in addition, 1,2-propandiol, 1,3-propandiol, butanediol (1,3), butanediol (1,4), hexanediol (1,6) and isomers, neopentylglycol or complex neopentylglycol ether hydroxypivalic acid and hexanediol (1,6) and isomers, butanediol (1,4), neopentylglycol and complex neopentylglycol ether hydroxypivalic acid are preferred. In addition, can also be used such polyols as trimethylolpropane, glycerin, aritra, pentaerythritol, trimethylbenzoyl or trihydroxystilbene.

As dicarboxylic acids can be used phthalic acid, isophthalic acid, terephthalic acid, tetrahydrophtalic acid, hexage rotalia acid, tikaexception acid, adipic acid, azelaic acid, sabotinova acid, glutaric acid, tetrachlorophthalic acid, maleic acid, fumaric acid, taconova acid, malonic acid, cork acid, 2-methylestra acid, 3,3-diacylglycerol acid and/or 2,2-dimethylxanthene acid. As the source of acid may also be used the corresponding anhydrides.

If the average functionality of the polyol, which should be subjected to esterification, >2, optionally together can also be used monocarboxylic acids such as benzoic acid and hexacarbonyl acid.

Preferred acids are aliphatic or aromatic acids of the above type. Particularly preferred are adipic acid, isophthalic acid and phthalic acid.

Hydroxycarbonate acids, which can be used as participants in the reaction together with obtaining complex polyetherpolyols with terminal hydroxyl groups are, for example, gidroksicarbonata acid, hydroxipropionic acid, hydroxydecanoic acid, hydroxystearate acid and the like. Suitable lactones are caprolactone, butyrolactone and homologues. It is preferable to caprolacton.

According to izobreteny is especially preferred as component A2) to obtain a polyurethane are complex polyether polyols with srednekamennogo molecular weight of from 600 to 3000 g/mol, in particular, aliphatic complex polyether polyols based on aliphatic carboxylic acids and aliphatic polyols, primarily on the basis of adipic acid and aliphatic alcohols such as hexanediol and/or neopentylglycol.

As component A2) may be used containing a hydroxyl group polycarbonates, preferably polycarbonatediol with srednekislye molecular mass Mnpreferably from 400 to 8000 g/mol, preferably from 600 to 3000 g/mol. These compounds can be obtained by reaction of the derivatives of carbonic acid, such as diphenylcarbonate, di methyl carbonate or phosgene, with polyols, preferably dialami.

Examples of such diols are ethylene glycol, 1,2 - and 1,3-propandiol, 1.3 - and 1.4-butanediol, 1,6-hexanediol, 1,8-octandiol, neopentylglycol, 1,4-bishydroxycoumarin, 2-methyl - 1,3-propandiol, 2,2,4-trimethylpentanediol-1,3, dipropyleneglycol, polypropyleneglycol, dibutylamino, polietilenglikoli, bisphenol a and lactobacillaceae diols of the above type.

Preferably diology component contains from 40 to 100% of the mass. hexandiol, preferred are 1,6-hexanediol and/or derivatives hexandiol. Such derivatives hexandiol based on hexanediol and in the end HE groups contain groups of complex or simple Firov. Such derivatives can be obtained by the reaction of hexanediol with excess caprolactone or by the esterification of hexandiol himself before the formation of di - or tridecylalcohol.

Instead of or in addition to clean polycarbonatediol in A2) can also be used simple politicalinternational.

Polycarbonates containing hydroxyl groups, preferably have a linear structure.

As component A2) may be used simple polyether polyols.

Especially suitable are, for example, known in polyurethane chemistry simple polytetramethylene, such as those obtained by polymerization of tetrahydrofuran by cationic disclosure cycle.

Suitable simple polyether polyols are also known products of the reaction of addition of steralised, ethylene oxide, propylene oxide, butilenica and/or epichlorohydrin di - or polyfunctional original molecules. So, usable are, in particular, polyalkylene glycols such as polyethylene, polypropylene and/or polietilenglikoli, first of all, having a preferred molecular weight above.

As a suitable source of molecules can be used all known issues of the prior art compounds, such as, for example, water, buildapi the ol, glycerin, diethylene glycol, trimethylolpropane, propylene glycol, sorbitol, Ethylenediamine, triethanolamine, 1,4-butanediol.

Particularly preferred components for A2) are simple polyester polytetramethylene and polycarbonatediol or mixtures thereof, and especially preferred is a simple polyester Paul tetramethylene chap and nick.

Thus, in preferred versions of the invention the components A2) are:

- mixtures containing at least one simple polyetherpolyols and at least one polycarbonatediol,

- mixtures containing more than one simple polyetherpolyols, or a mixture of several simple polyether polyols with different molecular masses, and we are talking primarily about simple polyether polyols of polytetramethylene (such as (BUT-(CH2-CH2-CH2-CH2-O)x'N),

- mixtures containing more than one simple polyetherpolyols, and at least one polycarbonatediol, and

particularly preferred complex polyether polyols with srednekamennogo molecular weight of from 600 to 3000 g/mol, in particular, aliphatic complex polyether polyols based on aliphatic carboxylic acids and aliphatic polyols, primarily on the basis of adipic acid and aliphatic alcohols, t is such as hexanediol and/or neopentylglycol,

moreover, according to the definition of component (A) mainly contains no ionic or ionogenic groups.

As component A3) can optionally be used polyols, first of all, non-polymeric polyols having a molecular weight in the preferred specified area from 62 to 399 g/mol, containing up to 20 carbon atoms, such as ethylene glycol, diethylene glycol, triethylene glycol, 1,2-propandiol, 1,3-propandiol, 1,4-butanediol, 1,3-butyleneglycol, cyclohexanediol, 1,4-cyclohexanedimethanol, 1,6-hexanediol, neopentylglycol, simple dihydroxyethyl ether of hydroquinone, bisphenol a (2,2-bis(4-hydroxyphenyl)propane), hydrogenated bisphenol a (2,2-bis(4-hydroxycyclohexyl)propane), trimethylolpropane, trimethylacetyl, glycerin, pentaerythritol, and also any mixtures with one another.

Suitable are esters of diols having a molecular weight in the above areas, such as complex α-hydroxybutanoic ether ε-hydroxypropranolol acid complex ω-hydroxyhexyloxy ether γ-hydroxybutiric acid, a complex of β-hydroxyethyloxy ester of adipic acid or a complex of bis-β-hydroxyethyloxy ester of terephthalic acid.

In addition, as component A3) can also be used monofunctional compounds with hydroxy groups are active towards isocyanates. Examples of such monofunctional the different compounds are ethanol, n-butanol, simple monobutyl ether of ethylene glycol, simple onomatology ether of diethylene glycol, simple monobutyl ether of diethylene glycol, simple onomatology ether of propylene glycol, simple onomatology broadcast dipropyleneglycol, simple onomatology broadcast tripropyleneglycol, simple monopropylene broadcast dipropyleneglycol, simple monobutyl ether of propylene glycol, simple monobutyl broadcast dipropyleneglycol, simple monobutyl broadcast tripropyleneglycol, 2-ethylhexanol, 1-octanol, 1-dodecanol, 1-hexadecanol.

In a preferred embodiment of the invention, the polyurethane used according to the invention, contains less than approximately 10% of the mass. component A3), preferably less than 5% of the mass. component A3), in each case calculated on the total weight of the polyurethane, more preferably, if the component A3) is not applied to obtain polyurethane.

As component A4) to obtain a polyurethane used according to the invention, if necessary, apply one or more first active towards isocyanates nonionic means increasing the hydrophilicity. A means of improving hydrophilicity used as component A4), are distinguished, in particular, from the components A2) and A3).

Suitable as component A4) non-ionic compounds that increase hydrof lnost, are, for example, a simple polyoxyalkylene esters, which have groups reactive towards isocyanates, such as hydroxy-, amino - or tirinya group. Preferred are monohydroxybenzene with statistically on average 5 to 70, preferably from 7 to 55 ethylenoxide structural units in the molecule simple polyalkyleneglycols, such as those that can be obtained by a known method by alkoxysilane suitable source of molecules (for example, in the publication Ullmanns Encyclopadie der technischen Chemie, 4. Edition, Band 19, Verlag Chemie, Weinheim, p.31-38). These compounds represent or pure ethers of polyethylene oxide or mixed ethers of polyalkylene, and they contain at least 30% mole., preferably at least 40% mole. ethylenoxide structural units, in terms of all contained acceleratedly structural unit.

Especially preferred nonionic compounds are monofunctional mixed polyethers of polyalkyleneglycol, which contain from 40 to 100% mole. ethylenoxide and from 0 to 60% by mole. propylenoxide structural units. Suitable source molecules for such non-ionic means increasing the hydrophilicity, are, in particular, saturated monosperma, such as such as methanol, this is ol, n-propanol, isopropanol, n-butanol, Isobutanol, torbutrol, isomeric pentanol, hexanol, octanol and nonanol, n-decanol, n-dodecanol, n-tetradecanol, n-hexadecanol, n-octadecanol, cyclohexanol, the isomeric methylcyclohexanols or hydroxymethylcellulose, 3-ethyl-3-hydroxyethyloxy or tetrahydrofurfuryl alcohol, simple monoalkyl ethers of diethylene glycol such as, for example, a simple monobutyl ether of diethylene glycol, unsaturated alcohols such as allyl alcohol, 1,1-dimethylallyl alcohol or oleic alcohol, aromatic alcohols such as phenol, the isomeric Cresols or methoxyphenols, arylaliphatic alcohols such as benzyl alcohol, anise alcohol or cinnamic alcohol, secondary monoamines such as dimethylamine, diethylamine, dipropylamine, Diisopropylamine, dibutylamine, bis(2-ethylhexyl)amine, N-methyl - and N-ethylcyclohexylamine or dicyclohexylamine, and also heterocyclic secondary amines such as morpholine, pyrrolidine, piperidine or 14-pyrazole. The preferred source molecules are saturated monoparty the above type. Especially preferred as a source of molecules used simple monobutyl ether of diethylene glycol or n-butanol.

Acceleratedly suitable for reaction alkoxysilane are, first of all, the ethylene oxide and propylene is oxide, when the reaction alkoxysilane can be used in any sequence or as a mixture.

Component b) is mainly chosen from primary or secondary amines and/or diamines. First of all, it includes diamines.

As component C) can primarily be used amines that do not contain ionic or ionic, such as anionic, group, imparting hydrophilicity (hereinafter component B1)), and it is also possible to use amines which contain ionic or ionic, such as, first of all, anionic groups, which imparts hydrophilicity (hereinafter component B2)). Preferably on stage) the conversion of the prepolymer is introduced into the reaction mixture of the component (B1) and the component B2).

As component B1) may be used, for example, organic di - or polyamine, such as, for example, 1,2-Ethylenediamine, 1,2 - and 1,3-diaminopropane, 1,4-diaminobutane, 1,6-diaminohexane, ISOPHORONEDIAMINE, mixture of isomers of 2,2,4 - and 2,4,4-trimethylhexamethylenediamine, 2-methylpentylamine, Diethylenetriamine, 4,4-diaminodicyclohexylmethane, hydrazinehydrate and/or dimethylethylenediamine.

In addition, as component B1) may also be used compounds which in addition to a primary amino group also contain secondary amino groups, or addition of an amino group (primary or secondary) also contain Oh-groups. The use of the AMI there are primary/secondary amines, such as diethanolamine, 3-amino-1-methylaminopropane, 3-amino-1-Ethylenediamine, 3-amino-1-cyclohexylamine, 3-amino-1-methylaminomethyl, aminoalcohols such as N-aminoethylethanolamine, ethanolamine, 3-aminopropanol, neopentanoate.

In addition, as component B1) may also be used monofunctional of amino compounds, active towards isocyanates, such as, for example, methylamine, ethylamine, Propylamine, butylamine, octylamine, laurylamine, stearylamine, isononylphenol, dimethylamine, diethylamine, dipropylamine, dibutylamine, N-methylaminopropyl, diethyl(methyl)aminopropyl, morpholine, piperidine, as well as their suitable substituted derivatives, amidoamine of amines with two primary amino groups and a monocarboxylic acids, monoketones of amines with two primary amino groups, primary/tertiary amines, such as N,N-dimethylaminopropylamine.

Preferably as component B1) are 1,2-Ethylenediamine, bis(4-aminocyclohexane)methane, 1,4-diaminobutane, ISOPHORONEDIAMINE, ethanolamine, diethanolamine and Diethylenetriamine. Particularly preferably, component b) contains at least one component B2). Suitable anionic compounds, which impart hydrophilicity, as component B2) preferably contain sulfoxylate or sulphonate group, particularly preferred is a recreational group sulfonate sodium. Suitable anionic compounds, which impart hydrophilicity, as component B2) are primarily salts of mono - and diaminoalkanes with alkaline metals. Examples of such anionic funds, giving hydrophilicity, are salts of 2-(2-aminoethylamino)econsultancy, ethylendiamine or butylsulfonyl, 1,2 - or 1,3-Propylenediamine-β-ethylsulfonyl or taurine. In addition, as anionic tools, giving hydrophilicity, can be applied salt cyclohexanedicarboxylate (CAPS) from the international application WO-A 01/88006.

Particularly preferred anionic means B2), which imparts hydrophilicity, are those which contain sulphonate groups as ionic groups and two amino groups, such as salts of 2-(2-aminoethylamino)ethylsulfonyl and 1,3-Propylenediamine-β-ethylsulfonyl.

Especially preferably the polyurethanes used according to the invention contain at least one sulphonate group. Optionally anionic group in the component B2) can also be a carboxylate or carboxyl group. In this case, the component B2) is preferably selected from diaminocarbenes acids. However, this variant of the invention is less preferred, because the components B2), based on the carboxylic key is lots, should be applied in higher concentrations.

To impart hydrophilicity can also apply a mixture of anionic gidrofilnami agents B2) and non-ionic gidrofilnami agents A4).

In a preferred embodiment of the invention for certain dispersions of polyurethane components A1) to A4) and B1) to B2) are used in the following quantities and individual components always sum up to 100% mass.:

from 5 to 40% wt. component A1),

from 55 to 90% of the mass. A2),

from 0.5 to 20% wt. the sum of components A3) and/or B1)

from 0.1 to 25 wt%. the sum of components A4) and/or B2), and in terms of the total amount of components A1) to A4) and B1) to B2) are particularly preferably used from 0.1 to 5 wt%. anionic or potentially anionic hydrophiloidea agent B2).

In a particularly preferred embodiment of the invention for certain dispersions of polyurethane components A1) to A4) and B1) to B2) are used in the following quantities and individual components always sum up to 100% mass.:

from 5 to 35 wt%. component A1),

from 60 to 90% Massa),

from 0.5 to 15 wt%. the sum of components A3) and/or B1),

from 0.1 to 15 wt%. the sum of components A4) and/or B2), and in terms of the total amount of components A1) to A4) and B1) to B2) are particularly Ave is doctitle used from 0.2 to 4% of the mass. anionic or potentially anionic hydrophiloidea agent B2).

In the most preferred embodiment of the invention for certain dispersions of polyurethane components A1) to A4) and B1) to B2) are used in the following quantities and individual components always sum up to 100% mass.:

from 10 to 30% of the mass. component A1),

from 65 to 85% Massa),

from 0.5 to 14 wt%. the sum of components A3) and/or B1),

from 0.1 to 13.5% of the mass. the sum of components A4) and/or B2), and in terms of the total amount of components A1) to A4) and B1) to B2) are particularly preferably used from 0.5 to 3.0 wt%. anionic or potentially anionic hydrophiloidea agent B2).

Obtaining dispersions of polyurethane can be carried out in a homogeneous environment in one or several stages or multi-stage method of turning partly in the dispersed phase. After fully or partially carried out from components A1) to A4) polyaddition preferably the stage dispersing, emulsifying or dissolving. At the end if necessary, additional polyprionidae or modification in the dispersed phase.

This can be applied all methods known from the issues of the prior art, such as, for example, the method of mixing the prepolymer is, the acetone method or the method of dispersion in the melt. Preferably applies the acetone method. Usually for acetone method components A2) to A4)and polyisocyanate component A1) to obtain a prepolymer containing isocyanate functional groups, load fully or partially, and optionally diluted able to mix with water but inert towards isocyanate groups with a solvent and heated to a temperature in the range from 50 to 120°C. To accelerate the reactions of addition of isocyanates can be used catalysts known in the chemistry of obtaining polyurethanes.

Suitable solvents are the customary aliphatic solvents containing ketogroup, such as, for example, acetone, 2-butanone, which can be added not only at the beginning of the retrieval process, but also, if necessary, later parts. Preferred are acetone and 2-butanone, especially preferred acetone. You can also add other solvents that do not contain groups that are active towards isocyanates, however, this is not preferred.

Then add the components A1) to A4)that have not yet been added to the beginning of the reaction.

Upon receipt of the polyurethane prepolymers of the components A1) to A4) the ratio which their quantities of substances for isocyanate groups against groups, active towards isocyanate, usually ranging from 1.05 to 3.5, preferably from 1.1 to 3.0, particularly preferably from 1.1 to 2.5.

The interaction of components A1) to A4) with the formation of the prepolymer proceeds partially or fully, however, it is preferable to full completion of the reaction. Thus, the polyurethane prepolymers which contain free isocyanate groups, obtained in the mass of the substance or in solution.

At the stage of neutralization for the partial or complete transfer of potentially anionic groups in the anionic groups are used bases, such as tertiary amines, for example, trialkylamine containing in each alkyl residue of 1 to 12, preferably from 1 to 6 carbon atoms, particularly preferably 2 to 3 carbon atoms, or in the highest degree preferably the base of the alkali metals, such as the corresponding hydroxides.

The use of organic amines is preferred.

As neutralizing agents can be preferably used inorganic bases such as aqueous ammonia or sodium hydroxide or potassium.

Preferred are sodium hydroxide and potassium hydroxide. The amount of material for the base is a value between 50 and 125% mole., preferably between 70 and 100% mole. the number ve is esta, containing acid groups, subject to neutralization. Neutralization can also be carried out simultaneously with the dispersion by the fact that the water dispersion contains a neutralizing agent.

In conclusion, in the next stage of the process, if this has not been done or has been done only partially, the resulting prepolymer was dissolved with aliphatic ketones, such as acetone or 2-butanone.

The interaction of components A1) to A4) with the formation of the prepolymer proceeds partially or fully, however, it is preferable to full completion of the reaction. Thus, the polyurethane prepolymers which contain free isocyanate groups, obtained in the mass of the substance or in solution.

When the elongation of the chain at the stage In) components containing NH2- and/or NH-functional groups interact with the remaining isocyanate groups of the prepolymer. Preferably the process of chain elongation/termination circuit is carried out prior to dispersion in water.

Preferred components B) for the process of chain elongation are, in particular, di - or polyamine B1), such as, for example, Ethylenediamine, 1,2 - and 1,3-diaminopropane, 1,4-diaminobutane, 1,6-diaminohexane, ISOPHORONEDIAMINE, mixture of isomers of 2,2,4 - and 2,4,4-trimethylhexamethylenediamine, 2-methylpentylamine, diethylene the Jamin, diaminodicyclohexylmethane and/or dimethylethylenediamine.

In addition, can also be used in connection B1), which in addition to a primary amino group also contain secondary amino groups, or addition of an amino group (primary or secondary) also contain Oh-groups. Examples thereof are primary/secondary amines, such as diethanolamine, 3-amino-1-methylaminopropane, 3-amino-1-Ethylenediamine, 3-amino-1-cyclohexylamine, 3-amino-1-methylaminomethyl, aminoalcohols such as N-aminoethylethanolamine, ethanolamine, 3-aminopropanol, neopentanoate used for elongation or breakage of the chain.

For a process of chain breakage commonly used amines B1)containing a group reactive towards isocyanates, such as methylamine, ethylamine, Propylamine, butylamine, octylamine, laurylamine, stearylamine, isononylphenol, dimethylamine, diethylamine, dipropylamine, dibutylamine, N-methylaminopropyl, diethyl(methyl)aminopropyl, morpholine, piperidine, as well as their suitable substituted derivatives, amidoamine of amines with two primary amino groups and a monocarboxylic acids, monoketones of amines with two primary amino groups, primary/tertiary amines, such as N,N-dimethylaminopropylamine.

If for chain elongation are used anionic means of improving hydrophilicity, with testwuide definition B2), the group containing NH2or NH, then the process chain-extending the prepolymer is preferably carried out before dispersing.

The degree of chain elongation, and therefore, the equivalent ratio of the groups active in respect of NCO-groups in the compounds used for chain elongation and chain termination, and the free NCO groups of the prepolymer, as a rule, is located in the region between 40 and 150%, preferably between 50 and 110%, particularly preferably between 60 and 100%.

Amine components B1) and B2) in the method according to the invention optionally may be used as diluted with water or solvent, separately or in mixtures, and, as a rule, any sequence of addition.

If together as a diluent used is water or an organic solvent, the diluent component, used In) chain elongation is preferably from 40 to 95% of the mass.

Preferably the dispersion is carried out at the end of the process of chain elongation. For this purpose, subject to dissolution and extending the chain of the polyurethane polymer, if necessary with a strong shearing force, such as, for example, intensive mixing, or brought in a water dispersion, or Vice versa, the water dispersion is mixed with the solution of the polyurethane polymer is, subjected to the process of chain elongation. Preferably water is added to the dissolved polyurethane polymer, subjected to the process of chain elongation.

The solvent still contained after the stage of dispersion in the dispersion, usually then removed by distillation. It is also possible destruction already in the process of dispersing.

The residual content of organic solvent in the polyurethane dispersions obtained in this way is usually less than 10 wt. -%, preferably less than 3 wt. -%, in terms of the whole variance.

The pH of the water dispersion of the polyurethane used according to the invention, usually less than an 8.0, preferably less than 7.5, especially preferably lies between 5,5 and 7,5.

Preferably compositions for skin care in the framework of the present invention may have the following form: cream, lotion, lotion, gel, oil, balm, water solution.

Compositions for skin care according to the invention preferably contain from 0.1 to 20% mass of the above-described polyurethane and, in particular, from 0.5 to 10% mass, in each case calculated on the total weight of the composition.

Composition for skin care according to the invention which contains the above-described polyurethane or its aqueous dispersion, should satisfy the above characteristics is the product for skin care. Composition for skin care according to the invention after the application of at least partially remains on the skin, particularly on the face, and, consequently, different, for example, cosmetic products, which when applied to the skin are removed, such as, for example, cosmetic masks and facial cleansing products, such as Soaps, etc. in Addition, the composition for skin care according to the invention generally also does not include tools for hair care. Compositions for skin care according to the invention, typically compositions are not makeup, such as cosmetics, etc., lipsticks and pencils makeup lips and lipsticks or the like.

In the framework of this invention, compositions for skin care differ primarily in their consistency: creams (viscous), lotions and milk (fluid), gel (semi-solid), oils and balms and aqueous solutions (liquid). In accordance with its structure compositions for skin care according to the invention can be applied, for example as creams, day or night creams, body lotions, etc. If necessary it is also possible that the composition according to the invention was used as pharmaceutically active ingredients or contain pharmaceutically active ingredients.

It is notizie for skin care may exist, for example, in the form of emulsions of oil-in-water, silicone-in-water, water in oil, water in silicone oil in water in oil, water in oil in water.

In addition, the composition may be subjected to foaming using a propellant. These emulsions can be stabilized by emulsifiers for emulsion of the type oil-in-water (M/W), water in oil (W/M) or water-in-silicone (B/Si), thickeners (for example, hydro-dispersion) or solids (such as, for example, emulsions of Pickering).

Compositions for skin care can contain one or more emulsifiers or surfactants.

Thus, in particular, emulsion oil in water (M/V) according to the invention preferably contain at least one emulsifier with products HLB value (hydrophilic-lipophilic balance)>7, and optionally a co-emulsifier.

Emulsifiers for oil-in-water (M/V) preferably can be selected from the group of nonionic, anionic, cationic or amphoteric emulsifiers.

In the group of nonionic emulsifiers are:

a) not fully esterified esters of fatty acids and esters of fatty acids with polyhydric alcohols and their ethoxylated derivatives

(b) ethoxylated fatty alcohols and fatty acids

c) ethoxylated fatty amines, amides, fatty acids, alkanolamine girn the x acids

d) simple alkylphenol ethers (for example, Triton® X)

e) ethoxylated ethers of fatty alcohols.

Particularly preferred nonionic emulsifiers for emulsion type M/b are ethoxylated fatty alcohols or fatty acids, preferably PEG-100 stearate, PEG-40 stearate, PEG-50 stearate, ceteareth-20, ceteth-20, steareth-20, ceteareth-12, ceteth-12, steareth-12, esters of mono-, oligo - or polysaccharides and fatty acids, preferably Clearinghouse, distearate methylglucose, glycerylmonostearate (savemarriage), esters sorbitan, such as, for example, servicestart (Tween® 20 and Tween® 60 by Uniqema), sorbitanoleat (Span® 40 company Uniqema), glyceryltrinitrate, esters of sucrose, such as, for example, sucrose stearate, PEG-20 methylglucose sesquistearate), esters of dicarboxylic acids and fatty alcohols (demonstarted).

Preferred anionic emulsifiers are Soaps (e.g. sodium or triethanolamine salts of stearic or palmitic acids)and esters of citric acid such as glyceryltrinitrate, sulfates of fatty alcohols, as well as complex mono-, di - and trialkylamines phosphoric esters and their ethoxylates.

In the group of cationic emulsifiers are quaternion ammonium compounds containing long is notaney aliphatic residue, for example, the chloride distearyldimonium.

In the group of amphoteric emulsifiers are:

a) alkylaminocarbonyl acid

b) betaines, sulfobetaine

c) derivatives of imidazoline.

In addition, there are the emulsifiers of natural origin, which include beeswax, wool wax, lecithin and sterols.

Suitable co-emulsifiers for emulsion type M/V according to the invention can be used fatty alcohols containing from 8 to 30 carbon atoms, complex monoglyceride esters of saturated or unsaturated, branched or unbranched alkenylboronic acids with a chain length from 8 to 24 carbon atoms, especially from 12 to 18 carbon atoms, a complex of propylene glycol esters of saturated or unsaturated, branched or unbranched alkenylboronic acids with a chain length from 8 to 24 carbon atoms, especially from 12 to 18 carbon atoms, and esters of sorbitol and of saturated or unsaturated, branched or unbranched alkenylboronic acids with a chain length from 8 to 24 carbon atoms, especially from 12 to 18 carbon atoms.

Particularly preferred co-emulsifiers are glycerylmonostearate, glycerylmonostearate, DigitalMaster, servicemonitor, distearate sucrose, cetyl alcohol, stearyl alcohol, beganovic alcohol,somegeneral alcohol and simple stearyl ether, polyethylene glycol (2) (steareth-2).

In the framework of this invention it may be preferable to use other emulsifiers. Thus, for example, further increase the stability of the compositions according to the invention to the water. Suitable emulsifiers are, for example, caprioli of alkylation and copolyol of alkyldimethyl primarily satellitecontrol, laurylamidopropyl, emulsifiers for water-in-oil (W/M), such as servicestart, literallayout, literallayout, sorbifolia, lecithin, glycerylmonostearate, polyglyceryl-3-oleate, polyglyceryl-3-diisostearate, PEG-7 gidrirovannoe castor oil, polyglyceryl-4-isostearate, cross-linked acrylate polymer/alkylacrylate with the number of carbon atoms in the alkyl of 10 to 30, serbianization, poloxamer 101, polyglyceryl-2-dipolyhydroxystearate, polyglyceryl-3-diisostearate, polyglyceryl-4-dipolyhydroxystearate, PEG-30-dipolyhydroxystearate, disasterology-3-diisostearate, picoliter, polyglyceryl-3-dipolyhydroxystearate.

Compositions according to the invention, such as, in particular, compositions of the type oil in water (M/V) preferably may contain thickeners for the aqueous phase. Preferred thickeners are:

Polymer stitched or unstitched Homo - or copolymers of acrylic acid or methacrylic acid. Here are IMEMO cross-linked homopolymers of methacrylic acid or acrylic acid, copolymerizate of acrylic acid and/or methacrylic acid and monomers that are derived from other acrylic or vinyl monomers, such as alkylacrylate with the number of carbon atoms in the alkyl of 10 to 30, alkyl methacrylates with the number of carbon atoms in the alkyl of 10 to 30, vinyl acetate and vinyl pyrrolidone.

- Polymers with thickening action of natural origin, for example based on cellulose, a guar gum, xanthan gum, scleroglucan, Gellan gum, Rhamsan gum (trade product of the company Kelco international is a polymer of D-glucopyranose acid, 6-deoxy-L-mannopyranose, D-glucopyranose available in the form of calcium-potassium-sodium salt) and gum karaya, alginates, maltodextrin, starch and its derivatives, gum carob, hyaluronic acid, carrageenan.

- Non-ionic, anionic, cationic or amphoteric associative polymers, for example based on polyethylene glycol and its derivatives, or polyurethanes.

Polymer stitched or unstitched the homopolymers or copolymers based on acrylamide or methacrylamide, such as homopolymers of 2-acrylamide-2-methylpropanesulphoacid, copolymers of acrylamide or methacrylamide and chloride of methacryloxypropyltrimethoxysilane or copolymers of acrylamide and 2-acrylamide-2-methylpropanesulphoacid.

Osobennostyami thickeners are thickening polymers of natural origin, polymer crosslinked Homo - or copolymers of acrylic acid or methacrylic acid, and the polymer crosslinked copolymers of 2-acrylamide-2-methylpropanesulphoacid.

Particularly preferred thickeners are xanthan gum, which are offered for sale by the firm CF Kelco under the trade designations Keltrol® and Kelza® or products of the company RHODIA with the trade designation Rhodopol, and guar gum, which is available as a product of the company RHODIA under the trade designation Jaguar® HP105.

Particularly preferred thickeners are cross-linked homopolymers of methacrylic acid or acrylic acid, which are commercially available as products company Lubrizol under the trade names Carbopol® 940, Carbopol® 941, Carbopol® 980, Carbopol® 981, Carbopol® ETD 2001, Carbopol® ETD 2050, Carbopol® 2984, Carbopol® 5984, and Carbopol® Ultrez 10, products 3V under the trade names Synthalen® K, Synthalen® L and Synthalen® MS.

The preferred thickeners are cross-linked copolymers of acrylic acid or methacrylic acid and alkylacrylate with the number of carbon atoms in the alkyl of 10 to 30 or alkylmethacrylamide with the number of carbon atoms in the alkyl of 10 to 30, as well as copolymers of acrylic acid or methacrylic acid and vinylpyrrolidone. Such copolymers are commercially available under the trade names Carbopol® 1342, Carbopol® 1382, Pemulen® TR1 or Pemulen® TR2 manufacturing firms is s Lubrizol, and trade names Ultrathix® R-100 (name in the International nomenclature of cosmetic ingredients, INCI (International Nomenclature for Cosmetic Ingredients): cross-linked polymer of acrylic acid/vinyl pyrrolidone) manufactured by ISP.

The preferred thickeners are crosslinked copolymers of 2-acrylamide-2-methylpropanesulphoacid. Such copolymers are commercially available under the trade name Aristoflex® AVC (name in the INCI nomenclature: copolymer acryloyldimethyltaurate ammonium / vinyl pyrrolidone) manufactured by Clariant.

These thickeners are usually present in concentrations from about 0% to 2 wt. -%, preferably from 0% to 1 wt. -%, in terms of the total weight of the composition according to the invention.

Other compositions according to the invention can be an emulsion type water in oil or water in silicone. Preferred are emulsions of water in oil (W/M) or emulsion of water in silicone (B/Si), which contain one or more silicone emulsifiers (B/Si) with products HLB value of ≤8 or one or more emulsifiers In a/M products HLB value <7, and optionally one or more emulsifiers M/V with products HLB value >10.

Silicone emulsifiers preferably can be selected from the group comprising alkyldimethylammonium, such as, for example, cetyl PEG/BCP 10/1, dimotiko copolyol (ABIL® EM 90 company Goldschmidt AG) or lauryl PEG/BCP-18/18 Dimethicone (Dow Corning® 5200 Dow Corning Ltd.), and dimethiconol, such as, for example, PEG-10 Dimethicone (KF-6017 company Shin Etsu), PEG/BCP-18/18 Dimethicone (Dow Corning 5225C from Dow Corning Ltd.) or PEG/BCP-19/19 Dimethicone (Dow Corning BY-11 030 Dow Corning Ltd.).

Emulsifiers for emulsion-type/M, with the value of the products HLB <7, preferably can be selected from the following groups: fatty alcohols containing from 8 to 30 carbon atoms, complex monoglyceride esters of saturated and/or unsaturated, branched and/or unbranched alkenylboronic acids with a chain length from 8 to 24 carbon atoms, especially from 12 to 18 carbon atoms, complex diglyceride esters of saturated and/or unsaturated, branched and/or unbranched alkenylboronic acids with a chain length from 8 to 24 carbon atoms, above all, from 12 to 18 carbon atoms, simple monoglyceride esters of saturated and/or unsaturated, branched and/or unbranched alcohols with a chain length from 8 to 24 carbon atoms, especially from 12 to 18 carbon atoms, simple diglyceride esters of saturated and/or unsaturated, branched and/or unbranched alcohols with a chain length from 8 to 24 carbon atoms, especially from 12 to 18 carbon atoms, a complex of propylene glycol esters of saturated and/or unsaturated, branched and/or unbranched alkenylboronic acids with a chain length of 8 to 24 atoms carbon primarily from 1 to 18 carbon atoms, and esters of sorbitol and saturated and/or unsaturated, branched and/or unbranched alkenylboronic acids with a chain length from 8 to 24 carbon atoms, especially from 12 to 18 carbon atoms.

Particularly preferred emulsifiers for systems/M are: glycerylmonostearate, glycerylmonostearate, glycerylmonostearate, glycerylmonostearate, DigitalMaster, DigitalMaster, propilenglikolmonostearata, propilenglikolmonostearata, propilenglikolmonostearata, propilenglikolmonostearata, servicemonitor, sorbitanoleat, servicemanagement, servicemonitor, distearate sucrose, cetyl alcohol, stearyl alcohol, arachidonoyl alcohol, beganovic alcohol, somegeneral alcohol, simple monorailway ether of glycerol, hemeroby alcohol, simple stearyl ether, polyethylene glycol (2) (steareth-2), glycerylmonostearate, glycerylmonostearate and glycerylmonostearate.

Other possible emulsifiers type systems for a/M are selected from the following group of compounds: polyglyceryl-2-dipolyhydroxystearate, PEG-30-dipolyhydroxystearate, cetyl-dimethiconol copolyol, polyglyceryl-3-diisostearate.

Emulsifiers for systems of M/V with products HLB value >10 preferably can be selected from the group comprising lecithin, trilaureth-4-phosphate, Polysorbate-20, poly is orbit-60, the copolymer PEG-22-dodecylphenol, sucrose stearate and sucrose laurate.

For stabilizirovannye emulsions/M according to the invention against precipitation or coagulation of drops of water may preferably be used thickener oils.

Particularly preferred thickeners oils are organically modified clay, such as organically modified bentonite (Bentone® 34 the company Rheox), organically modified hectorite (Bentone® 27 and Bentone® 38 company Rheox) or organically modified montmorillonite, pyrogenic silicic acid with hydrophobic properties, in which silanol groups substituted on trimethylsiloxy (AEROSIL® R812 company Degussa) or dimethylsiloxy group or polydimethylsiloxane (AEROSIL® R972, AEROSIL® R974 company Degussa, and CAB-O-SIL@TS-610, CAB-O-SIL® TS-720 firm Cabot), aluminum stearate or magnesium, or copolymers of styrene, such as, for example, styrene-butadiene-styrene, styrene-isoprene-styrene, styrene-ethylene/butene-styrene or styrene-ethylene/propene-styrene.

The thickening agent for the fatty phase may be contained in an amount of from 0.1 to 5 wt. -%, in terms of the total weight of the emulsion, and preferably in a quantity of from 0.4 to 3 wt. -%

In addition, the aqueous phase may contain a stabilizer. The stabilizer may represent, for example, sodium chloride, magnesium chloride or magnesium sulfate, and mixtures thereof.

Oil can use the camping in emulsions/M, B/Si and M/C.

In the presence of the fatty phase in the composition according to the invention it may contain non-volatile oil and/or volatile oils and waxes. Preferably the composition of the type M/contains from 0.01 to 45 wt%. oil, calculated on the total weight of the composition, and particularly preferably from 0.01 to 20 wt%. oil. Composition type/M or B/Si preferably contains at least 20% of the mass. oil, calculated on the total weight of the composition.

Non-volatile oil is preferably selected from the group of mineral, animal, vegetable or synthetic origin, polar or non-polar oil or mixtures thereof.

The lipid phase of the cosmetic and dermatological emulsions according to the invention preferably may be selected from the following group of substances:

mineral oils, mineral waxes, polar oils such as triglycerides of capric or Caprylic acid, in addition, natural oils, such as castor oil; fats, waxes and other natural and synthetic compounds of the fatty series, preferably esters of fatty acids and lower alcohols, e.g. isopropanol, propylene glycol or glycerol, or esters of fatty alcohols and lower alkanovykh acids or fatty acids; alkylbenzoates; silicone oils, such as dimethylpolysiloxane, diethylpropions, diphenylprolinol the Ana, and their mixed forms.

Polar oil is preferably selected from the following groups:

a) esters of saturated and/or unsaturated, branched and/or unbranched alkenylboronic acids with a chain length from 3 to 30 carbon atoms and saturated and/or unsaturated, branched and/or unbranched alcohols with a chain length from 3 to 30 carbon atoms,

b) esters of aromatic carboxylic acids and saturated and/or unsaturated, branched and/or unbranched alcohols with a chain length from 3 to 30 carbon atoms.

Such ester oils are in this case preferably can be selected from the following groups:

isopropylmyristate, isopropyl, isopropylene, isopropylacetate, n-butilstearat, n-exellent, n-decillia, isooctylphenol, economiseur, isononylphenol, isotretinoina, 2-ethylhexylamine, 2-ethylhexylamine, 2-hexyldecyl, 2-ethylhexylacrylate, 2-hexidecimal, 2-octyldodecanol, 2-ethylhexylamine, aerolef, realroot, erozilla, arazilerinin, disabilitant (Cetiol® CC), and cocoglyceride (Myritol® 331), and synthetic, semisynthetic and natural mixtures of such esters, e.g. jojoba oil.

c) Alkylbenzoates, alkylbenzoic with the number of carbon atoms in the alkyl of 12 to 15 (Finsolv® TN property is s Finetex) or 2-phenylethylamine (X-Tend® 226 firms ISP).

d) Lecithin and triglycerides of fatty acids, in particular, choose triglyceridemia esters of saturated and/or unsaturated, branched and/or unbranched alkenylboronic acids with a chain length from 8 to 24, especially 12 to 18 carbon atoms. For example, triglycerides of fatty acids can be selected from the following group: cocoglyceride, olive oil, sunflower oil, soybean oil, oil of groundnuts, rapeseed oil, almond oil, palm oil, coconut oil, castor oil, oil of wheat germ, the oil from grape seed, Thistle oil, evening primrose oil, oil of macadamia nut oil, apricot stone oil, avocado oil and many others like them.

e) Simple dialkyl ethers and diallylmalonate, preferred are, for example, a simple dicaprylyl ether (Cetiol® OE company Cognis) and/or disabilitant (for example, Cetiol® CC company Cognis).

f) Saturated or unsaturated, branched or unbranched alcohols, such as, for example, octyldodecanol.

Non-volatile oil is also preferably may be a non-polar oil is chosen from the group of branched and unbranched hydrocarbons, primarily, mineral oil, vaseline oil, paraffin oil, squalane and squalene, polyolefins, for example, polydecene, hydrogenosome the aqueous polyisobutene, isoparaffin with the number of carbon atoms from 13 to 16 and isohexadecane.

Non-polar non-volatile oil may be chosen from a number of non-volatile silicone oils.

From the non-volatile silicone oils can lead to polydimethylsiloxane (PDMS), which if necessary are phenylalanine, such as fenitrothion, or, if necessary, contain as substituents of aliphatic and/or aromatic groups, or functional groups, e.g. hydroxyl groups, thiol groups and/or amino groups; polysiloxane, modified fatty acids, fatty alcohols or polyoxyalkylene, and mixtures thereof.

Particularly preferred oils are 2-ethylhexylphthalate, octyldodecanol, isotretinoina, isoeicosane, 2-ethylhexylamine, alkylbenzoic with the number of carbon atoms in the alkyl of 12 to 15, Caprylic/capric triglyceride, simple dicaprylyl ether, mineral oil, disabilitant, cocoglyceride, butyleneglycol dicaprylate/dicaprate, hydrogenated polyisobutene, clarissenhof, isodecanoate, squalane, isoparaffin with the number of carbon atoms from 13 to 16.

In addition, the composition according to the invention may contain a wax. In this publication, the wax is determined as a lipophilic fatty substance which is solid at room tempera is ur (25°C), and with a melting point between 30°C and 200°C exhibits a reversible change of state of the solid/liquid. Above the melting point of the wax becomes low viscosity and is able to mix with oils.

Preferably the wax is selected from the group of natural waxes, such as, for example, wax cotton fiber, Carnauba wax, candle wax, Esparto wax, Japan wax, Montan wax, sugar cane wax, beeswax, wool wax, shellac, micrococci, ceresin, ozokerite, ouricuri-wax (obtained from likuri Palma), the wax from the fibers of the cork tree, lignite wax, Berrenwachs, oil from the seeds of the Shea tree or synthetic waxes, such as paraffin waxes, polyethylene waxes, waxes obtained by Fischer-Tropsch synthesis, hydrogenated oils, esters of fatty acids and glycerides that are solid at 25°C., silicone waxes, and derivatives (alkyl derivatives, CNS derivatives and/or esters of polymethylsiloxane), and mixtures thereof. The waxes may be present in the form of stable dispersions of colloidal particles of wax, which can be obtained by a known method, for example, in accordance with the publication "Microemulsions Theory and Practice", L.M. Prince Ed., Academic Press (1977), pages 21-32.

The wax may be contained in an amount of from 0 to 10 wt. -%, in terms of the total weight of the composition, and prefer is Ino from 0 to 5% of the mass.

In addition, the composition according to the invention may contain volatile oil, which is selected from the group of volatile hydrocarbon oils, siliconized oils or fluorinated oils.

The volatile oil may be contained in an amount of from 0 to 25 wt. -%, in terms of the total weight of the emulsion, preferably from 0 to 20% Messi even more preferably from 0 to 15% of the mass.

In this publication, the volatile oil is an oil, which upon contact with the skin at room temperature and atmospheric pressure to evaporate in less than one hour. Volatile oil at room temperature is liquid, as well as at room temperature and atmospheric pressure is the vapor pressure of from 0.13 up to 40,000 PA (10-3up to 300 mm Hg), preferably from 1.3 up to 13,000 PA (0.01 to 100 mmHg), and particularly preferably from 1.3 to 1300 PA (0.01 to 10 mmHg), and a boiling point of from 150 to 260°C., and preferably from 170 to 250°C.

Under the hydrocarbon oil see oil, which consists mainly of carbon atoms and hydrogen atoms and optionally oxygen atoms and nitrogen atoms and does not contain silicon atoms or fluorine, and it can also consist of carbon atoms and hydrogen atoms, and it may contain ester groups, ethers, amino group or amide group.

Under Seeley is oneiromancy oil see oil, which contains at least one atom of silicon, and, above all, groups Si-O-.

Under fluorinated oil should understand the oil, which contains at least one fluorine atom.

Volatile hydrocarbon oil according to the invention can be selected from the group of hydrocarbon oils having a flash point ranging from 40 to 102°C., preferably from 40 to 55°C., and still more preferably from 40 to 50°C.

Examples of volatile hydrocarbon oils are those having from 8 to 16 carbon atoms, and mixtures thereof, first and foremost, branched alkanes with the number of carbon atoms from 8 to 16, such as isoalkanes (also referred to as ISO)containing from 8 to 16 carbon atoms, isododecane, sodacan, isohexadecane, as well as, for example, oil, which is commercially available under the trade names Isopars® or Permetyls®and branched esters with the number of carbon atoms from 8 to 16, such as isohexanoate and mixtures thereof.

Especially preferred are volatile hydrocarbon oils such as isododecane, sodacan, isohexadecane.

Volatile siliconized oil according to the invention can be selected from among a siliconized oils having a flash point ranging from 40 to 102°C., preferably a flash point of more than 55°C and not higher than 95°C., and particularly preferably in the range from 65 d is 95°C.

As examples of volatile siliconized oils with non-branched chain or cyclic silicone oils containing from 2 to 7 silicon atoms, these silicones optionally contain alkyl or CNS group with the number of carbon atoms from 1 to 10.

Especially preferred are such volatile siliconized oils as octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, Dodecamethylcyclohexasiloxane, getmetricstatistics, getmetricstatistics, hexamethyldisiloxane, octamethyltrisiloxane, decamethylpentasiloxane, Dodecamethylcyclohexasiloxane, and mixtures thereof.

Volatile fluorinated oil, as a rule, has no flash point.

Examples are volatile fluorinated oil nonoperatively, nonformation, decipherment, tetracenomycin, dodecaborate, and mixtures thereof.

Preferred cosmetically acceptable medium of the composition according to the invention contains water and, if necessary, acceptable in cosmetics, able to mix with water suitable organic solvent.

Water used in the composition according to the invention, may be a floral water, clean demineralized water, mineral water, thermal water and/or seawater.

If kompozitsiaya M/as compositions according to the invention, the proportion of water may be in the range from 40 to 95 wt. -%, preferably in the range from 50 to 90 wt. -%, most preferably in the range from 60 to 80 wt. -%, in terms of the total weight of the composition. In the case of the composition type/M fraction of water is in the range from 0 to 60 wt. -%, preferably in the range from 10 to 50 wt. -%, most preferably in the range from 30 to 50 wt. -%, in terms of the total weight of the composition.

Preferred solvents are for example aliphatic alcohols with carbon atoms of 1 to 4, such as ethanol and isopropanol; polyols and their derivatives, such as propylene glycol, dipropyleneglycol, butylene-1,3-glycol, polypropyleneglycol, simple glycol ethers, such as simple alkalemia esters of mono-, di - or tripropyleneglycol or mono-, di - or triethylene glycol with a number of carbon atoms in the alkyl from 1 to 4, and mixtures thereof.

The number of one or more solvents in the compositions according to the invention can be, for example, in the range from 0 to 25 wt. -%, and preferably from 0 to 10 wt. -%, in terms of the total weight of the composition.

Compositions according to the invention for the manufacture of products for skin care can optionally contain additives which are customary in cosmetics, such as, for example, antioxidants, light protection means and/or other AIDS or additives, such as emulsifiers, p is supercial-active substances, defoamers, thickeners, surfactants, active ingredients, humidity regulators, fillers, UV filters, film-forming substances, solvents, additives for coalescence, aromatic substances, odor absorbers, perfumes and fragrances, geleobrazovanie and/or other dispersions of polymers, such as, for example, dispersion-based polyacrylates, pigments, dyes, tools that improve the spreading and/or thixotropic means, means for imparting elasticity, plasticizers/preservatives. The number of different additives for desired applications are known to the expert and are, for example, in the range from 0 to 25 wt. -%, in terms of the total weight of the composition.

Cosmetic composition according to the invention may also contain additives to impart sensory properties. Under additives for imparting sensory properties, you should understand colorless or white, mineral or synthetic, lamellar, spherical or oblong inert particles or not having the structure of individual particles of the additive, which, for example, further improve the sensory properties of the composition and, for example, leave the skin velvety or silky feeling.

Additives for imparting sensory properties of the composition according to the invention can contain, for example, in amounts of from 0 to 10 wt. -%, and before occhialino from 0 to 7 wt%, accordingly, calculated on the total weight of the composition.

Preferred additives for imparting sensory properties in the form of particles in the framework of the present invention are talc, transparent particles of the filler (mica, silica, kaolin, starch and its derivatives (for example, tapioca starch, phosphate microhyla, aluminum or sodium starch octenylsuccinate and the like), pyrogenic silicic acid, pigments, which mostly do not have any properties UV filter, nor a coloring effect (such as, for example, boron nitride etc), boron nitride, calcium carbonate, dicalcium phosphate, magnesium carbonate, magnesium bicarbonate, hydroxyapatite, microcrystalline the cellulose powder of synthetic polymers, such as polyamides (for example, polymers available under the trade name "Nylon®), polyethylene, poly-β-alanine, polytetrafluoroethylene ("Teflon®"), polyacrylate, polyurethane, lauroleic, silicone resin (for example, polymers available under the trade name "Tospearl®" by the company Kobo Products Inc.), hollow particles of polyvinylidene/Acrylonitrile (Expancel® Akzo Nobel) or hollow particles of silicon oxide (Silica Beads® company MAPRECOS).

Preferred additives for imparting sensory properties that do not have the shape of the particles can be selected from the group dimethiconol (for example, Dow Corning 1503 Fluid from Dow Corning Ltd.), copolymers Seeley the ones (for example, the copolymer divinitynation/dimeticone, Dow Corning HMW 2220 Dow Corning Ltd.) or silicone elastomers (for example, cross-linked polymer dimetikona, Dow Corning 9040 Silicone Elastomer Blend Dow Coming Ltd.).

The composition according to the invention may contain sunscreens, and the total number of sunscreen filters ranges from 0% of the mass. up to 30 wt. -%, preferably from 0 wt%. up to 20 wt. -%, particularly preferably from 0 wt%. up to 10 wt. -%, in terms of the total weight of the composition according to the invention. Sunscreens (UV filters) can be selected from among organic filters, physical filters, as well as mixtures thereof.

The composition according to the invention may contain UV-a, UV-filters or broadband filter. Used UV filters can be soluble in oils or water-soluble. Needless to say, the list below UV filter is not restrictive.

For UV-b filters should be called, for example:

- (1) salicylic acid derivatives, in particular, homogentisate, octisalate and complex 4-isopropylbenzyl ester of salicylic acid;

- (2) derivatives of cinnamic acid, above all, 2-ethylhexyl-p-methoxycinnamate, which are commercially available under the trade name Parsol MCX® company Givaudan, as well as complex isopentylamine ether 4-methoxycatechol acids;

- (3) liquid Ave is spodnie β,β'-diphenylacetate, in particular 2-ethylhexyl α,β'-diphenylacetate or octocrylene, which is included in the sale by the company BASF under the trade name UVINUL N539®;

- (4) derivatives of p-aminobenzoic acid, in particular, complex 2-ethylhexyloxy ether 4-dimethylaminobenzoyl acid complex amyl ether 4-dimethylaminobenzoyl acids;

- (5) derivatives of 3-benzylideneacetone, in particular, 3-(4-methylbenzylidene)camphor, which is supplied by the company Merck under the trade name EUSOLEX 6300®, 3-benzylideneamino, benzylideneacetone acid, as well as polyaryletheretherketone;

- (6) 2-phenylbenzimidazol-5-acid, which is supplied by the company Merck under the trade name EUSOLEX 232®;

- (7) derivatives of 1,3,5-triazine, first of all, 2,4,6-Tris[p-(2'-ethylhexyl-1'-oxycarbonyl)aniline]-1,3,5-triazine, which is included in the sale by the company BASF under the trade name UVINUL T150®, and deactivatedelegation, which is included in the sale by the company 3V Sigma under the trade name UVASORB NEUVE®;

- (8) esters of benzylmalonate acid, in particular, complex di-(2-ethylhexyloxy) ether 4-methoxybenzeneboronic acid, and a copolymer of 3-(4-(2,2-biotoxicological)phenoxy)propenyl)methoxyethoxide /dimethylsiloxane that comes in the sale of the company Roche Vitamines under the trade name Parsol® SLX, and

- (a) a mixture of these filters.

As UV-a filters should be called, for example:

- (1) derivative dibenzoylmethane, especially 4-(tertbutyl)-4'-methoxydibenzoylmethane, which is included in the sale by the company Givaudan under the trade name PARSOL 1789®, as well as 1-phenyl-3-(4'-isopropylphenyl)propane-1,3-dione;

- (2) benzene-1,4-[di(3-metaliterature-10-acid)], optionally fully or partially neutralized form, commercially available under the trade name MEXORYL SX® company Chimex;

- (3) complex hexyl ester of 2-(4'-diethylamino-2'-hydroxybenzoyl)benzoic acid (also aminobenzophenone);

- (4) derivatives of silanes or polyorganosiloxanes containing benzophenone group;

(5) anthranilate, especially methylanthranilate, which is supplied by the company Symrise under the trade name NEO HELIOPAN MA®;

- (6) compounds in which one molecule contain at least two benzazolyl group or at least one benzodiazapine group, in particular, 1,4-bisbenzimidazole-3,3',5,5'-tetracarboxylate, as well as its salts, which are supplied in the sale of the company Symrise;

- (7) containing silicon derivatives benzimidazolylthio which are N-substituted, or benzofurazanyl, in particular, 2-[1-[3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl]propyl]-1H-benzimidazole-2-yl]benzoxazole, 2-[1-[3-[1,3,3,3-tetrameth the-1-[(trimethylsilyl)oxy]disiloxanyl]propyl]-1H-benzimidazole-2-yl]benzothiazole, - 2-[1-(3-trimethylsilylpropyne)-1H-benzimidazole-2-yl]benzoxazole, - 6-methoxy-1,1'-bis(3-trimethylsilylpropyne)-1H, 1 N-[2,2']dibenzyldithiocarbamate, - 2-[1-(3-trimethylsilylpropyne)-1H-benzimidazole-2-yl]benzothiazole, which is described in European patent application EP-A-1028120;

- (8) triazine derivatives, in particular 2,4-bis[5-(1-dimethylpropyl)benzoxazol-2-yl-(4-phenyl)imino]-6-(2-ethylhexyl)imino-1,3,5-triazine, which is included in the sale by the company 3V under the trade name Uvasorb® K2A, and

- (9) mixtures thereof.

As broadband filters should be, for example:

- (1) derivatives of benzophenone, such as, 2,4-dihydroxybenzophenone (benzophenone-1); - 2,2',4,4'-tetrahydroxybenzophenone (benzophenone-2); - 2-hydroxy-4-methoxybenzophenone (benzophenone-3), which is included in the sale by the company BASF under the trade name UNIVNUL M40®; - 2-hydroxy-4-methoxybenzophenone-5-acid (benzophenone-4)and its sulfate form (benzophenone-5), which is included in the sale by the company BASF under the trade name UVINUL MS40®; - 2,2'-dihydroxy-4,4'-dimethoxybenzophenone (benzophenone-6); - 5-chloro-2-hydroxybenzophenone (benzophenone-7); - 2,2'-dihydroxy-4-methoxybenzophenone (benzophenone-8); the disodium salt of 2,2'-dihydroxy-4,4'-dimethoxybenzophenone-5,5'-disulfonate (benzophenone-9); - 2-hydroxy-4-methoxy-4'-methylbenzophenone (benzophenone-10); - benzophenone-11; 2-hydroxy-octyloxybenzophenone (benzophenone-12).

- (2) triazine derivatives, in particular 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine, which is included in the sale by the company Ciba Geigy under the trade name TINOSORB S®, and 2,2'-Methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-TETRAMETHYLBUTYL)phenol], which is included in the sale by the company Ciba Geigy under the trade name TINOSORB M®; and

- (3) 2-(1 H-benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[1,1,3,3-tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl]propyl]phenol], which is represented in the INCI nomenclature as trisiloxane drometrizole.

Can also be used a mixture of several filters and a mixture of UV-b filters, UV-a filters and broadband filters, as well as mixtures with physical filters.

From a group of physical filters can lead barium sulfate, titanium oxide (titanium dioxide, amorphous or crystalline in the form of rutile and/or anatase), zinc, iron, zirconium, cerium, silicon, manganese or mixtures thereof. The metal oxides may be present in the form of particles with a size in the micrometer region or nanometer region (nanopigments). The average size of particles for nanopigments comprise, for example, from 5 to 100 nm.

Compositions for skin care according to the invention, furthermore, may contain regulators humidity.

Especially preferred regulators humidity or moisturizers as part of this, and the finding are for example, glycerin, polyglycerol, sorbitol, dimetridazole, lactic acid and/or lactates, in particular sodium lactate, butyleneglycol, propylene glycol, biosaccharide gum-1, soybean glycine, hydroxyatomoxetine, Ethylhexylglycerin, pyrrolidinecarbonyl acid, and urea. In addition, particularly advantageous is the use of polymer humidifier from the group of water-soluble and/or is able to swell in water and/or capable of forming a gel with water polysaccharides. In particular, preferred are, for example, hyaluronic acid, chitosan and/or a polysaccharide with a high content of trokosi that comes in the sale of the company Gesellschaft SOLABIA S.A. under the trade name Fucogel® 1000.

Particularly preferably in this invention can be used water-soluble antioxidants, such as vitamins, for example, ascorbic acid and its derivatives. Highly preferred are vitamin E and its derivatives, as well as vitamin a and its derivatives.

Other preferred active substances in the composition according to the invention are α-hydroxy acid such as glycolic acid, lactic acid, malic acid, tartaric acid, citric acid and mandelic acid, β-hydroxy acids such as salicylic acid, and takeee acylated derivatives 2-hydroxyalkanoate acids and their derivatives; natural active substances and/or their derivatives, such as, for example, alpha-lipoic acid, folic acid, fiten, D-Biotin, coenzyme Q10, alpha-glucosylrutin, carnitine, carnosine, natural and/or synthetic isoflavones, creatine, creatinine, taurine and/or [beta]-alanine, as well as 8-hexadecene-1,16-dicarboxylic acid (Dioic acid, CAS number 20701-68-2, pre-designation in the INCI nomenclature octadecenyl acid) and/or licochalcone And, as well as herbal extracts.

The invention is explained in more detail using Examples, and should not be construed as limiting. All data on quantities, units and interest components related to the mass of the total amount or, respectively, to the total mass of the composition, unless otherwise indicated.

Examples

Unless otherwise stated, all analytical measurements refer to measurements at 23°C.

Solids or solids is determined by heating a weighed sample to 125°C to a constant weight. Upon reaching a constant weight using a re-weighting of the sample is calculated solids content.

The content of NCO-groups, unless specifically mentioned otherwise, were carried out by volumetric titration in accordance with DIN-EN ISO 11909.

To the control of the availability of free NCO-groups is carried out using infrared spectroscopy (band at 2260 cm -1).

Given viscosity values were determined using rotational viscometry in accordance with DIN 53019 at 23°C using a rotational viscometer of the company Anton Paar Germany GmbH, Ostfildern, Germany.

Determination of average particle sizes of the dispersions of polyurethane (see srednekamennogo value) was carried out after dilution with deionized water by means of laser correlation spectroscopy (LCS) (Malvern instrument Zetasizer 1000, firms Malvern Inst. Limited).

Used substances and abbreviations:

Diaminoethane:NH2-CH2CH2-NH-CH2CH2-SO3Na (45%solution in water)
Desmophen® 2020/C2200:polycarbonatediol, HE is number 56 mg KOH/g, srednekislye molecular weight 2000 g/mol (firm Voeg MaterialScience AG, Leverkusen, Germany)
PolyTHF® 2000:polytetramethylene, HE is number 56 mg KOH/g, srednekislye molecular weight 2000 g/mol (BASF AG, Ludwigshafen, Germany)
PolyTHF®1000:polytetramethylene, HE is number 112 mg KOH/g, srednekislye molecular weight of 1000 g/mol (firm BASFAG, Ludwigshafen, Germany)
Polyether LB 25:simple monofunctional polyether based on ethylene oxide/propylene oxide, srednekislye molecular weight
2250 g/mol, IT is the number of 25 mg KOH/g (Bayer MaterialScience AG, Leverkusen, Germany)

Example 1: the Dispersion of polyurethane 1

987,0 g of PolyTHF® 2000 (component A2)), 375,4 g of PolyTHF® 1000 (component A2)), 761,3 g of Desmophen® C2200 (component A2)), and 44.3 g of Polyether LB 25 (component A4)) was heated to 70°C standard mechanical mixer apparatus. Then was added a mixture of 237,0 g hexamethylenediisocyanate (component A1)) and 313,2 g isophorondiisocyanate (component A1)) and stirred at 120°C until then, until he reached theoretical value of the content of NCO-groups. The finished prepolymer was dissolved in 4830 g of acetone and cooled at 50°C and then added to the solution, consisting of a 25.1 g of Ethylenediamine (component B1)), 116,5 g isophorondiamine (component B1), of 61.7 g diaminoethane (component B2)) and 1030 g of water. Subsequent stirring was 10 minutes Then received the dispersion by adding 1250 g of water. After that followed the separation of the solvent by distillation in vacuum.

The obtained dispersion white had the following characteristics:

Solids content:61%
The size of the particles (LKS):312 nm
Viscosity (viscosity, 23°C):241 MPa·s
pH (23°C):6,02

Example 2: Dispersion of polyurethane 2

450 g of PolyTHF® 1000 (component A2)), 2100 g of PolyTHF® 2000 (component A2)) were heated to 70°Statem was added a mixture of 225,8 g hexamethylenediisocyanate (component A1)) and 298,4 g isophorondiisocyanate (component A1)) and was stirred at 100-115°C. until then, until he reached theoretical value of the content of NCO-groups. The finished prepolymer was dissolved in 5460 g of acetone at 50°C and then added to the solution comprising of 29.5 g of Ethylenediamine (component B1)), 143,2 g diaminoethane (component B2)) and 610 g of water. Subsequent stirring was 15 minutes Then received the dispersion by adding 1880 g of water. After separating the solvent by means of distillation in a vacuum and has been stable during storage of the dispersion.

Solids content:56%
The size of the particles (LKS):276 nm
Viscosity:1000 MPa·s

Example 3: the Dispersion of polyurethane 3

1649,0 g complex polyester of adipic acid, hexanediol and neopentyl glycol with an average molecular weight 1700 g/mol (component A2)) were heated to 65°C. Then was added 291,7 g hexamethylenediisocyanate (component A1)) and was stirred at 100-115°C. until then, until he reached theoretical value of the content of NCO-groups. The finished prepolymer was dissolved in 3450 g of acetone at 50°C and then added to the solution, consisting of a 16.8 g of Ethylenediamine (component B1)), 109,7 g diaminoethane (component B2)) and 425 g of water. Subsequent stirring was 15 minutes Then received the dispersion by adding 1880 g of water. After separating the solvent by means of distillation in a vacuum and has been stable during storage of the dispersion.

Solids content:42%
The size of the particles (LKS):168 nm
Viscosity:425 MPa·s
PH:7,07

Example 4: the Dispersion of polyurethane 4

340 g of a complex of the polyester from adipic acid, hexanediol and neope the Teal glycol with an average molecular weight 1700 g/mol (component A2)) were heated to 65°C. Then added 60.1 g of hexamethylenediisocyanate (component A1)) and stirred at 105°C until until you have reached theoretical value of the content of NCO-groups. The finished prepolymer was dissolved in 711 g of acetone at 50°C, and then was added a solution consisting of 2.1 g of Ethylenediamine (component B1)), 32,4 g diaminoethane (component B2)) and the 104.3 g of water. Subsequent stirring was 15 minutes Then received the dispersion by adding 1880 g of water. After separating the solvent by means of distillation in a vacuum and has been stable during storage of the dispersion.

Solids content:40%
The size of the particles (LKS):198 nm
Viscosity (viscosity, 23°C):700 MPa·s
PH:of 6.31

Example 5: the dispersion of the polyurethane 5

450 g of PolyTHF® 1000 (component A2)) and 2100 g of PolyTHF® 2000 (component A2)) were heated to 70°C. Then was added a mixture of 225,8 g hexamethylenediisocyanate (component A1)) and 298,4 g isophorondiisocyanate (component A1)) and was stirred at 100-115°C until until you have reached theoretical value of the content of NCO-groups. Ready the second prepolymer was dissolved in 5460 g of acetone at 50°C, and then was added a solution consisting of 351 g diaminoethane (component B2)) and 610 g of water. Subsequent stirring was 15 minutes Then received the dispersion by adding 1880 g of water. After separating the solvent by means of distillation in a vacuum and has been stable during storage of the dispersion.

Solids content:40%
Viscosity:1370 MPa·s

EXAMPLES of USE

Quantitative data in the following Tables are % of the mass. in terms of the total number of songs.

The emulsion of the type oil in water (M/In)

td align="center"> 4,0
12345678910
The polyurethane dispersion according to the invention (% mass. in terms of solid matter)2,05,08,02,0 15,03,010,02,05,02,0
Glyceryltrinitrate2,0
Literallayout savemarriage2,0
Distearate polyglyceryl-3-methylglucose2,52,0
Servicestart 1,0
PEG-40 stearate0,5
Literallayout2,50,52,02,0
PEG-100 stearate2,0
Staroignat sodium 0,50,2
Distearyldimonium1,0
Stearic acid1.0
Beganovic alcohol1,0
Cetyl alcohol 2,5
Cetearyl alcohol2,05,010,02,0
Ministerului alcohol2,0
Stearyl alcohol1,01,03,01,0
Cross-linked polymer of acrylate/alkylacrylate with the number of carbon atoms 10-301 0,10,80,3
The copolymer of acryloyldimethyltaurate ammonium/vinylpyrrolidone (VP)20,5
Cross-linked polymer of acrylic acid/VP30,60,2
Carbomer0,840,330,56
Dimethylpolysiloxane
Simple dicaprylyl ether1,03,01,0
Myristyl myristate3,01,0
Octyldodecanol1,04,05,03,0
1Pemulen TR-1, firm Lubrizol
2Aristoflex AVC, the firm Clariant
3UltraThixP-100, the company ISP
4Carbopol 980, firm Lubrizol
5Carbopol Ultrez 10, the company Lubrizol
6Carbopol 981, firm Lubrizol

Butyleneglycol dicaprylate/dicaprate2,03,0
Alkylbenzoic with the number of carbon atoms in the alkyl 12-153,03,05,01,0
Isohexadecane 2,03,0
Caprylic/katrinaville2,02,0
Cyclomethicone4,02,02,01,0
Dimethicone2,01,02,05,01,0
Mineral oil5,02,5
Hydrogenated polyisobutene2,0
Venetianskt5,0
Isodecanoate2,0
Evening primrose oil 2,0
Oil from the seeds of the Shea tree2,0
Butyleneglycol5,0
Glycerin107,55,03,0108,05,05,0
Denaturired the config alcohol 3,04,0
Tapioca starch71,01,0
Phosphate microhyla2,0
Aluminum starch octenylsuccinate82,0
Sodium starch octenylsuccinate92,0
Butylperoxybenzoate4
Octocrylene5
Phenylbenzimidazole22
Ethylhexylacrylate5
Three three-and EDTA11
The active ingredientq.s.q.s.q.s.q.s.q.s.q.s.q.s.q.s.q.s.q.s.
Neutralizing agentq.s.q.s.q.s.q.s.q.s.q.s.q,s.q.s. q.s.q.s.
Dyeq.s.q.s.q.s.q.s.q.s.q.s.q.s.q.s.q.s.q.s.
Perfumeq.s.q.s.q.s.q.s.q.s.q.s.q.s.q.s.q.s.q.s.
Preservativeq.s.q.s.q.s.q.s.q.s.q.s.q.s.q.s.q.s.q.s.
Waterup to 100%up to 100%up to 100%up to 100%up to 100%up to 100%up to 100% up to 100%up to 100%up to 100%
q.s. - enough
7Tapioca Pure, company National Starch
8Dry Flo PC, the company National Starch
9Cleargum CO 01, company Roquette

The emulsion of the type water-in-oil (W/M)

td align="justify" namest="c0" nameend="c5"> q.s. - enough
12345
The polyurethane dispersion according to the invention (% mass. in terms of solid matter)2,05,08,02,010,0
Polyglyceryl-3 diisostearate1,0
Polyglyceryl-2 dipolyhydroxystearate3,03,0
PEG-40 servicepersonal3,0
Triglyceriderich0,5
Digitalentertainment1,5
PEG-30 dipolyhydroxystearate0,25
PEG-22 dodecyl glycol copolymer5,0
PEG-45 dodecyl glycol polymer1,0
Lanolin alcohol1,0is the 0,30,5
Beganovic alcohol0,5
Caprylic/katrinaville15,015,0
Mineral oil10,08,010,08,010,0
Microcrystalline wax5,01,0
Disabilitant1,0
Isopropylmalate8,0
Isopropylamine is at 1,0
Castor oil1,0
Vaseline6,05,0
Octyldodecanol1,03,0
Hydrogenated cocoglyceride2,0
Evening primrose oil0,5
The aluminum stearate0,30,60,5
Magnesium sulfate0,51,00,50,50,5
Sodium citrate0,50,30,050,2
Sodium chloride10,0
Citric acid0,10,20,2
Potassium sorbate0,150.4
Glycerin3,08,05,03,0
Talc0,5
E is anal 2,0
The active ingredientq.s.q.s.q.s.q.s.q.s.
Neutralizing agentq.s.q.s.q.s.q.s.q.s.
Dyeq.s.q.s.q.s.q.s.q.s.
Perfumeq.s.q.s.q.s.q.s.q.s.
Preservativeq.s.q.s.q.s.q.s.q.s.
Waterup to 100%up to 100%up to 100%up to 100%up to 100%

The emulsion of the type water-in-silicone (B/Si)

12
The polyurethane dispersion according to the invention (% mass. in terms of solid matter)5,010,0
Copolyol cetyl Dimethicone2,0
Cetyl PEG/BCP-10/1 Dimethicone3,0
Cyclomethicone15,025,0
Dimethicone15,05,0
Fenitrothion1,0
Hydrogenated polyisobutene2,0
Dimethiconol1,0
Xanthan gum100,1
Glycerin 5,02,0
Magnesium sulfate1,0
Sodium chloride0,7
Citric acid0,3
Sodium citrate0,9
Potassium sorbate0,3
The active ingredientq.s.q.s.
Neutralizing agentq.s.q.s.
Dyeq.s.q.s.
Perfumeq.s.q.s.
Preservativeq.s.q.s.
Waterup to 100%up to 100%
q.s. - enough
10Keltrol CG-T, the Irma WED Kelco

The hydro-dispersion

1234
the polyurethane dispersion according to the invention (% mass. in terms of solid matter)2,510,05,08,0
Cetearyl alcohol + PEG-40 castor oil - clearesult sodium2,5
Servicestart1,0
Cetearate-200,5
The copolymer of acryloyldimethyltaurate ammonium /vinylpyrrolidone111,0
Cross-linked polymer of acrylate/alkylacrylate with the number of carbon atoms 10-3012 0,80,31,0
Xanthan gum130,5
Octyldodecanol2,02,02,0
Caprylic/katrinaville3,03,02,0
Cyclomethicone4,02,0
Isodecanoate3,0
Dimethicone2,0
Disabilitant2,0
Sodium starch octenylsuccinate the t 1,5
Tapioca starch3,01,0
Alcohol3,0
Glycerin5,02,05,02,0
Ethylhexylacrylate8,0
Octocrylene5,0
Phenylbenzimidazole2,0
Ethanol5,0
Sodium starch octenylsuccinate14 0,5
The active ingredientq.s.q.s.q.s.q.s.
Neutralizing agentq.s.q.s.q.s.q.s.
Dyeq.s.q.s.q.s.q.s.
Perfumeq.s.q.s.q.s.q.s.
Preservativeq.s.q.s.q.s.q.s.
Waterup to 100%up to 100%up to 100%up to 100%
11Aristoflex AVC, the firm Clariant
12Pemulen TR-1, firm Lubrizol
13Keltrol CG-T, IDF is s CP Keico
14Cleargum CO 01, company Roquette

1. Composition for skin care containing at least one polyurethane, which can be obtained by the interaction of one or more insoluble in water, unable to dispergirujutsja in water polyurethane prepolymers with isocyanate functional groups (A) with one or more compounds containing amidofunctional groups selected from primary and/or secondary amines and/or diamines and additives.

2. Composition for skin care according to claim 1, which is insoluble in water, unable to dispergirujutsja in water polyurethane prepolymers with isocyanate functional groups And mostly not contain any ionic or ionogenic groups.

3. Composition for skin care according to claim 1 or 2, in which connection amidofunctional groups) include at least one diamine.

4. Composition for skin care according to claim 1 or 2, in which connection amidofunctional groups) are selected from compounds with amidofunctional groups B2), which contain ionic and/or ionogenic groups, and connections with amidofunctional groups B1)that do not contain ionic and/or ionogenic groups.

5. Composition for skin care according to claim 1 or 2, in which the connection with aminofen the national groups) include at least one connection with amidofunctional groups B2), which contain ionic and/or ionogenic groups, preferably 2-(2-aminoethylamino)econsultation and/or a salt thereof.

6. Composition for skin care according to claim 1 or 2, in which compounds with amino groups) include at least one connection with the amine groups B1), which does not contain ionic and/or ionogenic groups, preferably a diamine that does not contain ionic and/or ionogenic groups.

7. Composition for skin care according to claim 1 or 2, in which connection amidofunctional groups) include compounds with amidofunctional groups B2), which contain ionic and/or ionogenic groups, and compounds with amidofunctional groups B1)that do not contain ionic and/or ionogenic groups.

8. Composition for skin care according to claim 1 or 2, in which the prepolymers (A) can be obtained by reacting one or more polyols selected from the group consisting of simple polyether polyols, polycarbonatediol, simple politicalinternational and/or complex polyether polyols with one or more polyisocyanates.

9. Composition for skin care according to claim 1 or 2, in which the polyurethane contains at least one sulfonylurea and/or sulphonate group, preferably a group of the sulfonate sodium.

10. Composition for skin care according to claim 1 or 2, characterized in that Thu is it contains at least one active substance and/or one humidity controller.

11. The use of a composition containing at least one polyurethane, which can be obtained by the interaction of one or more insoluble in water, unable to dispergirujutsja in water polyurethane prepolymers with isocyanate functional groups (A) with one or more compounds containing amidofunctional groups selected from primary and/or secondary amines and/or diamines and supplements for skin care.



 

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FIELD: medicine.

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FIELD: medicine.

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FIELD: medicine.

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15 cl, 14 ex

FIELD: medicine.

SUBSTANCE: invention refers to a composition with the property of hair growth-stimulating effect. The declared composition contains at least one aromatase inhibitor specified in a group of chemically synthetised aromatase inhibitors, and soya bean and rape extracts, as well as at least one herbal extract. The above extract contains one or more biologically active substances extracted from plants and specified in a group consisting of type I and/or type II 5α-reductase inhibitors and androgen receptor blockers. Also, the invention refers to using the declared composition for cosmetic application and body or face hair growth reduction and/or scalp hair growth stimulation.

EFFECT: invention provides the controlled hair growth and pigmentation effect.

15 cl, 14 ex

FIELD: medicine.

SUBSTANCE: invention refers to a composition with the property of hair growth-stimulating effect. The declared composition contains at least one aromatase inhibitor specified in a group of chemically synthetised aromatase inhibitors, and soya bean and rape extracts, as well as at least one herbal extract. The above extract contains one or more biologically active substances extracted from plants and specified in a group consisting of type I and/or type II 5α-reductase inhibitors and androgen receptor blockers. Also, the invention refers to using the declared composition for cosmetic application and body or face hair growth reduction and/or scalp hair growth stimulation.

EFFECT: invention provides the controlled hair growth and pigmentation effect.

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FIELD: medicine.

SUBSTANCE: invention refers to cosmetology and represents a cosmetic composition for making hair care products, containing amino acids, proteins, saccharides, vitamins, functional additives and water, differing by the fact that it additionally contains shark liver oil with the ingredients of the composition taken in certain proportions, wt %.

EFFECT: invention provides reducing hair loss considerably.

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FIELD: medicine.

SUBSTANCE: invention refers to cosmetology and represents a cosmetic composition for making hair care products, containing amino acids, proteins, saccharides, vitamins, functional additives and water, differing by the fact that it additionally contains shark liver oil with the ingredients of the composition taken in certain proportions, wt %.

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EFFECT: valuable medicinal antitumor properties of preparation.

8 cl, 4 tbl, 2 dwg, 4 ex

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