Method of treating chronic tonsillitis
SUBSTANCE: invention refers to medicine, namely otorhinolaryngology and may be used for treating chronic tonsillitis. That is ensured by ultrasound sanation of tonsils with the use of 0.05% chlorhexidine followed by Lugol's solution phonophoresis. The ultrasound sanation involves exposure on each tonsil for 60 seconds. The phonophoresis procedure involves contact exposure on each tonsil for 20 seconds. The therapeutic course is 10 daily procedures.
EFFECT: method provides microbiocoenosis recovery, anti-inflammatory action, reduced cicatricle changes in tonsil tissues, as well as mediated action on immunological processes.
The invention relates to medicine, in particular to otolaryngology and physical therapy, and can be used for the treatment of patients with chronic tonsillitis.
Chronic tonsillitis is an active with periodic exacerbations of chronic inflammatory nidus of infection in the tonsils with a total infectious and allergic reaction and occupies a Central place in tonsillar pathology.
Chronic tonsillitis is characterized as multifactor immunopathological process, contributes to the development of systemic complications, burdening their pathogenesis, and plays a role in the trigger mechanism in the development of cardiovascular, neuroendocrine, immunologic, and metabolic syndrome.
There is a method of treatment of chronic tonsillitis with apparatus " Tonsillar"including ultrasonic reorganization of the tonsils using as a remedy 0.1% solution of hydrogen peroxide followed by phonophoresis with interferon ointment
(Mechaniken NV and other "Application of ultrasonic installation "Tonsilar for the treatment of chronic tonsillitis", M, 1984, p.43-56).
The disadvantage of this method is the low efficiency of treatment, due to the fact that interferon has a limited range of impact as it affects local humoral immunodeficiency is itet, while chronic tonsillitis etiological factor is a bacterial infection and the appearance of scarring of the Palatine tonsils.
There is a method of treatment of chronic tonsillitis, including ultrasonic reorganization of the tonsils with the use of the medicinal product followed by phonophoresis drugs (U.S. Pat of the Russian Federation No. 2152773, CL AN 23/00, publ. 20.07.2000, In this way as a remedy drug use Malavet, and treatment is carried out in three stages, first by ultrasonic reorganization of the tonsils with the use of an aqueous solution of the drug Malawi in a dilution of 1:5, followed by low-frequency phonophoresis with Malavita in a dilution of 1:2, after which patients carry out rinsing the mouth with a solution of Malavita in a dilution of 1:20.
The disadvantages of this method are: first, the limited scope, due to the fact that Malawi is bad with an unknown concentration of the medicinal substance, it collapses under the influence of ultrasound, secondly, has a low treatment efficiency, due to the absence of a full impact on the scar-modified tissue of the tonsils, which are often present in chronic tonsillitis.
In accordance with this task, aimed at empowering with the woman, and increase the effectiveness of treatment through the full effects of the drugs used on all the mechanisms of pathogenesis of chronic tonsillitis, that ensures the recovery of the functional state of the lymphoid tissue of the tonsils.
To solve this problem in the treatment of chronic tonsillitis, including ultrasonic reorganization of the tonsils with the use of the medicinal product, followed by phonophoresis drugs proposed as a drug when ultrasonic sanitation use of 0.05% chlorhexidine solution, and phonophoresis - Lugol solution with ultrasonic sanitation impact exercise for every palate the amygdala within 60 seconds, while phonophoresis contact on each of the velum amygdala within 20 seconds, while the course of treatment is 10 daily procedures.
The use of 0.05% chlorhexidine solution for ultrasonic sanitation and Lugol solution for phonophoresis provides the impact on the scar tissue, which are usually present in chronic tonsillitis. This contributes to the increase of microorganisms, determining normies this biotope. Reduce representatives of conditionally pathogenic flora. Reduce the volume of the tonsils due to complete removal of pathological content of the gaps and reducing inflammation of the tissues of the tonsils. As a result of this reduced the frequency of exacerbations and increase remission chronic tone is illite.
The method is as follows.
Low-frequency ultrasonic sanitation is carried out in ENT or dental chair in a semi-sitting position of the patient whose head is turned towards the voice tonsils. Conduct local aerosol anesthesia of the pharynx to suppress the pharyngeal reflex, a solution of anesthetic (lidocaine 10%) depending on the age of the patient and individual tolerability of the drug. After applying to the amygdala applicator with funnel required size include electroadhesive, crane applicator set in the "open"position. The vacuum regulator on electroadhesive establish the vacuum in the system of the applicator is of the order of 0.3 to 0.4 kgf/cm2required for the drainage of fixing the applicator on the amygdala and implementation of additional vacuum drainage gaps from pathological content, as well as suction and circulation through the funnel medicinal solution chlorhexidine 0.05 percent. Voiced chlorhexidine has a strong bactericidal, fungicidal and virucidal effect on the infection site. After filling funnel applicator with an antiseptic solution set the exposure time scoring include a control unit and spend processing tonsil ultrasound through the recirculating solution ozone is consistent chlorhexidine when the parameters 3-4 Hz and exposure times scoring one tonsil 60 seconds. In the aggregate arising in liquid pharmaceutical environment, under the influence of high-amplitude Ncus: cavitation, alternating sound pressure, acoustic currents and high-speed liquid jet directed onto the surface of the tonsils, provide for the destruction and erosion of surface protein layers, expansion and disclosure mouths gaps and crypts and leaching of these pathological content, including caseous plugs, initiating the "direct" and "reverse" ultrasonic capillary effects in the parenchyma and capillary-paristay lacunar system of the amygdala, followed by extraction of pathological content and drainage gaps and crypts, impregnation them in antiseptic solution. Specified in the final analysis, leads to the intensification of the treatment of the tonsils from pathological content, inactivation of pathogenic microflora, depositing medicinal substance in purified, in the process of sanation, gaps and crypts of the tonsils, rendering a positive therapeutic effect.
The next stage is realized by the contact of the low-frequency ultrasonic impregnation in a pre-sanitized lacunas of tonsils drugs that stimulate the repair of the tonsil parenchyma. For this purpose, the waveguide-instrument with a Cup-shaped radiant face, the which before the procedure attached to the speaker system. On the Cup-shaped sluchayem end technological fix the gasket 2-3 layers of gauze impregnated with Lugol solution, after which the waveguide is a tool intermittently (without effort) press to Sineu the surface of the tonsils. Include a control unit and 3-4 Hz for 20 seconds on each of the palatal tonsil spend phonophoresis tools.
Specific examples of the implementation of the method
Example 1. Patient K. 43 years. Diagnosis: Chronic tonsillitis, simple form. Sick for 10 years, in the history of the disease: angina once. Constantly bothered by discomfort in the throat when swallowing, sore, sore throat in the morning. When laringoscopice inspection: congestive hyperemia of the mucosa, thickening of the edges of the Palatine arches, Palatine tonsils loose, fusing them with nebnymi fit in the gaps of the tonsils contain caseous plugs, Muco-purulent discharge. The patient was performed sanitization of the tonsils apparatus "Tonsillar" with chlorhexidine 0.05%, the frequency of 3-4 Hz, exposure time 60 seconds on each amygdala, a course of 10 treatments.
The second stage was carried out phonophoresis of Lugol solution, a frequency of 3-4 Hz, exposure time 20 seconds on each amygdala, 10 procedures.
Example 2. Patient M., 28 years. Diagnosis: Chronic tonsillitis, toxico-allergic form I. Ill within 12 years, with exacerbations 1-2 times per year. The patient complained of bad breath, sore throat in the morning. During the inspection it was noted congestive hyperemia of the diffuse nature of the mucous membrane of the Palatine arches, the tonsils, the thickening of the edges of the Palatine arches, Muco-purulent contents in the gaps of the tonsils. The patient was held ultrasonic cavitation Palatine tonsils with chlorhexidine 0.05% device "Tonsillar", a frequency of 3-4 Hz, exposure time 60 seconds on each tonsil, then phonophoresis of Lugol solution, a frequency of 3-4 Hz, exposure time 20 seconds on each amygdala. The course of treatment consisted of 10 sessions.
The method of treatment of chronic tonsillitis, including ultrasonic reorganization of the tonsils with the use of the medicinal product, followed by phonophoresis medicines, characterized in that as a drug when ultrasonic sanitation use of 0.05%chlorhexidine solution, and phonophoresis - Lugol solution with ultrasonic sanitation impact exercise for every palate the amygdala 60 seconds, and when phonophoresis - pin on each Palatine of the amygdala within 20 s, the course of treatment is 10 daily procedures.
SUBSTANCE: invention refers to medicine, specifically dermatovenerology. Baneocin ointment is used as an agent for topical treatment of infiltrative-suppurant trichophytosis capitis for 48 hours with underlying conventional systemic antimycotic therapy. The agent shows manifested antimicrobial, anti-inflammatory, resolving and regenerative effect.
EFFECT: invention extends the range of topical products for treating infiltrative-suppurant trichophytosis capitis.
SUBSTANCE: invention refers to medicine, namely surgery, and concerns skin and soft tissue wound and wound infection healing. That is ensured by using tissue coatings impregnated by a phytotherapeutic substrate in the following proportions: eucalyptus leave extract - 30.0 gram; pot marigold blossom extract - 10.0 gram; purple Echinacea herb extract - 10.0 gram; distilled water to 1000.0 ml.
EFFECT: method provides higher clinical effectiveness ensured by an ability of the phytotherapeutic substrate to clean the wounds fast from necrotic elements and providing a faster process of natural healing.
SUBSTANCE: invention refers to medicine. A method involves daily abscess cavity sanitation, sanitation liquid evacuation. Then the abscess cavity is filled with a copper nanoparticle suspension in physiologic saline in the concentration of 100 mcg/ml, exposing for 30 min to be evacuated thereafter.
EFFECT: method provides fast and effective growth inhibition of pathogens in the abscess cavity, intensifies hepatic regeneration, normalises hepatic function.
3 dwg, 1 ex
SUBSTANCE: invention refers to medicine, dentistry, and is applicable for preventing and treating dental diseases of teeth and oral cavity. For this purpose, a surface of gums and teeth is exposed to an optical range, and the exposure is combined with tooth brushing with using a tooth paste. The tooth brushing is combined with exposure of the oral mucosa opposite to the teeth. The tooth paste is presented by a tooth paste with a photosensitiser. Wave length of the emission directed to the teeth is specified to be close to the wave length of photosensitiser excitation. Wave length of the emission directed towards the oral mucosa opposite to the teeth is specified in a short-wave optical spectrum.
EFFECT: method provides improved antimicrobial, anti-inflammatory, anti-caries action ensured by stimulation of cell restoration processes, improvement of local tissue circulation and nutrition, relieved oral irritation and inflammation.
5 cl, 1 dwg
SUBSTANCE: invention relates to veterinary science. The preparation contains pumpkin sludge 84-86%, walnut concentrate 10-12%, the preparation Metrosept 2-3%, emulsifier T2 1-2%.
EFFECT: preparation is safe for animals, effective in treating inflammatory processes and wound surfaces, possesses prolonged action.
4 tbl, 1 ex
SUBSTANCE: invention relates to compounds of general formula (I), where R is n-C12H25 or n-C16H33.
EFFECT: compounds of formula having bactericidal and fungicidal properties.
1 cl, 1 dwg, 1 tbl, 3 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutics. A composition contains nanosized silver powder, nanosized aluminium powder and nanosized diamond powder in the following proportions, wt %: nanosized silver powder - 40, aluminium powder -30, nanosized diamond powder -30.
EFFECT: composition shows a combined immunomodulatory and antibacterial effect, low toxicity.
3 tbl, 1 ex
SUBSTANCE: invention relates to a method of producing concentrates of nanodispersions of zerovalent metals such as silver, gold, copper, palladium, platinum and mercury, which have antiseptic properties. Said method involves mixing a solution of a soluble metal salt in a solvent with ammonia to obtain a complex which is then mixed with alkalnolamine to form a solution. The obtained solution is mixed with a solution of a polymer stabiliser to obtain a stabilised metal cation which is then reduced by adding to the solution an organic or inorganic reducing agent to form a stable dispersion of metal nanoparticles. The disclosed method is realised at a defined ratio of components for 10-60 minutes in an air atmosphere at temperature of up to 100°C.
EFFECT: invention is aimed at obtaining metal dispersions with high sedimentation and chemical resistance and high antiseptic power, which are compatible with a physiological NaCl solution; the method also cuts duration of synthesis and considerably simplifies the process, increases efficiency and complete conversion of cationic metal into a zerovalent metal.
38 cl, 3 tbl, 104 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine and is applied in surgery, dermatology, obstetrics, gynaecology and otorhinolaryngology for treating pyoinflammatory processes of soft tissues and mucous membranes. An agent contains the following components, mass fractions: as a base - enterosgel (60.0-80.0), as therapeutic components, an antiseptic - 0.05% chlorhexidine bigluconate (20.0-40.0), and a regeneration stimulator - methyluracil (2.0-4.0).
EFFECT: invention provides the therapeutic agent possessing antiseptic, wound-healing and sorption functions.
4 tbl, 2 ex
SUBSTANCE: group of inventions refers in particular to solutions for mouth rinsing. The water based composition possessing antimicrobic activity consists of: a) from 0,001 to 10 % of weight octenidin dihydrochlorid b) from 0,05 to 30 % of weight of not ionic surface-active substance - derivative fat acids, c) from 0,01 to 10 % of weight poliol, chosen from 1,2-propylene glycol, 1,3 propylene glycol, butane-1,4-diol, sorbite (hexa-1,2,3,4,5,6-hexole) and glycerin or their mix, d) from 0,05 to 10 % of weight of fruit acid and-or its salt chosen from lemon acid, dairy acid, apple acid, wine acid, glycogenic acids, fumaric and amber acid or their mix, e) from 0,025 to 10 % of weight of flavour and-or sweetener, chosen from alitam, aspartame, dulcin, neohesperidin DC, stevioside, sucralose, suosane and thaumatinor their mixtures with water - up to 100 %. The composition is applied as a solution for mouth rinsing and controlling S. Aureus and/or E. faecalis resistant to methicillin.
EFFECT: invention provides efficiency of application as the solution for mouth rinsing awhich is characterized by pleasant taste and a small tendency to foaming.
11 cl, 2 ex
SUBSTANCE: invention relates to field of biotechnology. Claimed is protein, including catalytic fragment of sialidase and possessing sialidase activity, which is selected from protein, whose sequence includes amino acids 274-666, or 274-681, or 290-666, or 290-681 SEQ ID NO:12, or includes amino acid sequence SEQ ID NO:14, described herein. Described is fused protein, which includes described above protein and anchor domain. Also given is information about molecules of nucleic acids, which code said proteins, expression vectors, containing said nucleic acids, and pharmaceutical compositions, containing said protein or fusion protein. Claimed is method of treatment or prevention of viral infection, caused by virus of influenza or parainfluenza, including application of therapeutically efficient amount of said composition to epithelial cells of subject.
EFFECT: invention makes it possible to extend arsenal of means against infection, caused by influenza or parainfluenza vitus.
25 cl, 2 tbl, 13 dwg, 17 ex
SUBSTANCE: invention refers to medicine, namely balneology and balneotherapy, and concerns treating pharyngitis. That is ensured by gargarism with using hydrosulphuric mineral water of the Ust-Kachka resort of total mineralisation 76 g/dm3, hydrogen sulphide concentration 300 mg/dm3, at 18-20°C dissolved 1:5 to final concentration 50 mg/dm3, once a day, daily in the therapeutic course of 10-14 days.
EFFECT: method provides effective treatment of pharyngitis ensured by the high concentration of biologically active substances in mineral water.
SUBSTANCE: what is offered is the use of viferon as an agent for prevention of postoperative laryngeal paresis following thyroidectomy.
EFFECT: minimised risk of postoperative laryngeal paresis following thyroidectomy with preserved anatomical continuity of recurrent laryngeal nerves, as well as adequate reduction of the rate of postoperative hypocalcemia from 38% to 32%.
2 tbl, 1 ex
SUBSTANCE: invention relates to medicine and can be used for treatment of larynx papillomatosis. For this purpose treatment is performed in two stages. At the first stage larynx papillomas are ablated in endoscopic way under general anesthesia with application of CO2- laser. After decrease of post-operation edema at the second stage session of photodynamic therapy with application of 5-aminolevulinic acid chloride is carried out. 1.5-2 hours before the session 3.0 grams of preparation alasens are diluted in 200 ml of distilled water and are given to patient to drink in amount 30-50 mg/kg of body weight. After that, target zone is irradiated by laser with has power 250-300 mV/ cm2 by fibre-optic conductor with cylindrical disperser by means of helium-neon laser with wavelength 632.8 nm. Total energy dose is 150-180 J/cm2. Patient is placed into a darkened room until evening.
EFFECT: method makes it possible to achieve sanitation and eradication of small unremoved pieces of papillomas and long recurrence-free period.
SUBSTANCE: invention relates to medicine, namely to otolaryngology, and can be applied in complex treatment of post-traumatic injuries of larynx. For this purpose in treatment included is daily infusion into larynx of 1.0 ml of perfluorane during 3-5 days.
EFFECT: invention makes it possible to reduce terms and increase treatment efficiency due to anti-oxidant, cytoprotective and membrane-stabilising properties of pefluorane, in addition, gas-transport properties of perfluorane favour local influence on trophism of muscular tissues of vocal ligaments, which results in increase of voice resistance to loads.
SUBSTANCE: invention relates to medicine, namely to otolaryngology, and can be applied for treatment of chronic pharyngitis. For this purpose intranasally solution, which contains novocaine and mexidol, is introduced.
EFFECT: invention ensures efficient treatment of said diseases by stimulation of local antivirus protection, suppression of non-residential microflora vegetation on mucous tunic of gullet, anti-inflammatory action, improvement of local microcirclation and stimulation of reparation processes.
4 cl, 4 tbl
SUBSTANCE: invention relates to medicine, namely to otolaryngology, and can be applied for treatment of chronic pharyngitis. For this purpose intranasallly solution, which contains novocaine and lazolvan, is introduced.
EFFECT: invention ensures efficient treatment of said diseases due to stimulation of local antivirus protection, suppression of non-residential microflora vegetation on mucous tunic of gullet, anti-edematous and anti-inflammatory action.
4 cl, 4 tbl
SUBSTANCE: invention relates to medicine, namely to otolaryngology, and can be applied for treatment of chronic pharyngitis. For this purpose solution, which contains novocaine and lazolvan and mexidol is introduced intranasally. Additionally is perorally vitamin D3 is introduced.
EFFECT: invention ensures efficient treatment of said diseases and maintenance of stable clinic effect due to stimulation of local antivirus protection, suppression of non-residential microflora vegetation on mucous tunic of gullet, anti-edematous and anti-inflammatory action, improvement of local microcirclation and stimulation of reparation processes.
5 cl, 4 tbl
SUBSTANCE: invention relates to medicine, otolaryngology, and can be used for treatment of chronic adenoiditis and tonsillitis in children. For this purpose sanation and immunocorrection are carried out. Sanation is carried out with sodium chloride solution at temperature 37-40°C one procedure daily during 7-10 days. After that additionally light therapy is performed by exposure of bridge of the nose and/or left and right sides of the neck to noncoherent polarised light with wavelength 400-2000 nm and density of light energy flow 2.4 J/cm2, degree of polarisation at outlet 95-98%, for 5-10 minutes daily during 7-10 days. Immunocorrection is performed by medication tonsilotren sublingually 30-60 minutes before meal daily 3 times with 6-8 hour interval in amount 125-500 mg during 7-10 days.
EFFECT: method allows to increase efficiency of local and general immunisation, improve results of treatment of chronic adenoiditis and tonsillitis in children, reduce treatment terms.
1 tbl, 2 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to medical agents and concerns a tablet for local throat and oral cavity treatment by diffusion transmucosal diffusion of lipophilic molecules, including a composition which contains: - derivative of alkylcarboxyl family and/or another lipophilic anti-inflammatory substance or antimycotic lipophilic substance in the form of lysine salts of these molecules, and a polymeric agent in combination with substrate selected from carbohydrates family. Also the invention discloses application of the tablets for obtaining a medical agent for throat and mouth cavity treatment by transmucosal diffusion.
EFFECT: tablets act locally at the same level as the diseases and inflammations, in much smaller doses, and cause no side effects leading to immediate therapeutic effect.
SUBSTANCE: invention relates to medicine, physiotherapy. Method includes drug treatment, mud applications on extremities, impact with ultrasound and electrophoresis, hydrokinesitherapy, hydrogen sulfide baths. Peripheral relaxants, vasoactive preparations, group "B" vitamins, chondroprotectors, painkillers are used. At the first stage sulfide silt mud application of glove type are performed at temperature 30 - 40°C, during 10 minutes, every second day, the course includes 5 procedures. Impact on collar zone with ultrasound with hydrocortisone, 0.4 W/cm2, is performed daily during 10 minutes, the course includes 5 procedures. Hydrokinesotherapy is performed at water temperature 38°C. At the second stage calcium electrophoresis is performed on collar zone during 2 days, daily, with 5-6 mA, for 20 minutes. Complex of exercises for osteoporosis is carried out. At the third stage sauna for 20 minutes and hydromassage in water at temperature 38°C for 10 minutes are carried out daily during five days. After that, exercises for relaxation and stretching of muscle groups are performed. At the fourth stage hydrogen sulfide baths are carried out at temperature 37°C, for 10 minutes, during five days. After that, complex of dynamic exercises and exercises for hands are performed.
EFFECT: method reduces degree of functional disorders of central nervous system, restores mobility in joints, increases bone mineral density and strength.
2 ex, 3 tbl