Two-layer surgical prosthesis for soft tissue replacement
SUBSTANCE: invention refers to medicine. What is described is a prosthesis, particularly for treating hernias and/or abdominal hernias by the intraperitoneal introduction, containing a fibre mesh of a non-absorbable and biologically compatible polymer material having lumens enabling tissue engraftment, and a sheet of polymer material possessing the barrier properties and having poor adhesion to sensible organs and tissues. The sheet is applied on the mesh and coupled therein to form a layered structure. The sheet is attached to the mesh by means of a number of connective fibres adjoining each other with a gap making max. 5 mm. Each fibre has a number of attachment points to the mesh at a distance of max. 15 mm, and each fibre section between the two adjoining attachment points projects from the mesh surface facing the sheet and welded to the sheet.
EFFECT: prosthesis has reduced weight for reduction of the inflammatory reaction and abdominal rigidity, and improved patient's comfort and quality of life.
10 cl, 3 dwg
The present invention relates to a surgical prosthesis for replacement of soft tissues, in particular for the treatment of hernias and/or abdominal hernia, or defects of the abdominal wall, by intraperitoneal injection.
More specifically, this prosthesis contains a grid of fibers and non-absorbable biocompatible polymeric material having openings that allow the germination of the fabric and the sheet of polymeric material having barrier properties and having a weak adhesion to sensitive organs and tissues, and the sheet placed on the grid and connected with her for the formation of the layered structure.
In operation, the prosthesis is implanted so that the grid was in contact with the abdominal wall, strengthen and stimulate fibroblastic reaction, and the barrier layer were in contact with internal organs to minimize sticking.
Known prosthesis of this type is described in U.S. patent No. 6270530. In this prosthesis grid is connected with the sheet with the help of one of the intermediate grid, which is sewn to the first grid on the one hand and preplavljena to the barrier sheet to another using a process based on the creation of high temperature and pressure.
The presence of one of the intermediate grid makes the design of the prosthesis rather thick, hard and heavy. As a result, its hard to turn for the introduction of br is used cavity, using a trocar (i.e. instrument, which, after creation of pneumoperitoneum makes possible the introduction of surgical instruments through the holes made in the abdominal wall), which limits opportunities for implantation. In addition, a large amount of material present in these prostheses, contrary to the concept of "less is more"made U.Klinge and V.Schumpelick in the "Prosthetic implants for hernia repair" BJS, Vol.90 (12), Dec.2003:1457-1458. According to this concept, the quantity and quality of the inflammatory response directly correlates with the number of implanted prosthetic material and the surface area in contact with tissue of the body. In particular, this inflammatory response is the cause of the formation of scar tissue, which covers the grid, giving it rigidity and causing discomfort and pain to the patient.
Therefore, the objective of the present invention to provide an improved prosthesis in comparison with the known prostheses.
According to the invention results from the surgical prosthesis for replacement of soft tissues, in particular for the treatment of hernias and/or abdominal hernias by intraperitoneal injection containing the grid, made from fibers of polypropylene having openings that allow the germination of the fabric, and a sheet made of stretched polytetrafluoroethylene having barrier is foistware and having weak adhesion to sensitive organs and tissues, moreover, the sheet placed on the grid and connected with her for the formation of the layered structure through a set of connective fibers arranged next to each other with a gap constituting not more than 5 mm, and each of the connecting fiber has many places of attachment to the grid with a distance between them of not more than 15 mm, and each fiber span between two adjacent seats of attachment is on the surface of the grid facing the sheet, and problable to the sheet.
Connective fibers may be made from polypropylene.
The ratio of the diameters of the connecting fibers and the fibers forming the mesh may be in the range between 1.1 and 2.
Connective fibers can be located next to each other with a gap constituting not more than 3 mm, and preferably between 1 and 2 mm Connective fibers can be located, essentially, with the same clearances.
Stretches the connective fibers between two adjacent seats of attaching the fiber to the grid can have a length of not more than 10 mm and preferably between 5 and 9 mm of the Specified line segments connecting fibers can have essentially the same length, so the insertion of various connective fibers are arranged in rows parallel to each other and essentially perpendicular to the adjacent line segments to connect the sustained fashion fibers.
The sheet may be connected with the connecting fibers by hot rolling.
The prosthesis can have only the mesh and sheet, United connective fibers.
In the prosthesis according to the invention the connective fibers act as spacer elements located between the mesh and the sheet to prevent damage to the grid and/or integrity of the barrier film during the process of fusing them with the sheet and prevent overlap of openings of the grid. At the same time, the connective fibers have mass and stiffness, much smaller than the intermediate mesh or other connecting means, which simplifies handling of the prosthesis and improves the flexibility of the prosthesis according to the invention.
Therefore, the design created prosthesis allows the implant to trim it to the required shapes and sizes without any damage and loss of fibers grid collapsed for introduction into the abdominal cavity using a trocar, and easy to spread it on the anatomical site of implantation.
After implantation of the prosthesis according to the invention has such elasticity and strength so that, for example, to provide a response that is compatible with normal physiological responses and anatomical and biomechanical dynamics of the abdominal wall without separation of the grid from the sheet and/or without a perforated sheet mesh.
Approximately t Lina prosthesis according to the invention lies in the range between 0.4 and 0.6 mm, the weight per unit area of the surface lies in the range between 60 and 100 g/m2and the tensile strength is greater than the maximum intra-abdominal pressure measured using the principle of hydrostatics Pascal and equal to 16 N/cm, as determined Klinge u, Klosterhalfen Century, Conze j, and others in the "Modified mesh for hernia repair that is adapted to the discrimination of abdominal wall", Eur J Surg 164:951-960, 1998.
In General, the prosthesis according to the invention has a smaller thickness, which allows to embed it using a trocar having small dimensions and reduced weight to reduce the inflammatory response and rigidity of the abdominal wall and improve comfort and quality of life of the patient.
Other advantages and features of the present invention will become apparent from the following detailed description which is given with reference to the attached drawings, given solely as a non-limiting example, which depicts the following:
figure 1 is a view in partial mirovom prosthesis according to the invention;
2 is a top view in an enlarged scale of the grid, forming part of the prosthesis depicted in figure 1;
3 is a view in section in an enlarged scale along the line III-III in figure 1.
Surgical prosthesis for replacement of soft tissues, in particular for the treatment of hernias and/or abdominal hernias by intraperitoneal injection, contains a grid 10 of non-absorbable fibers Biologicheskie compatible synthetic polymer material such as polypropylene, having openings that allow the germination of the fabric, and a sheet 12 of polymeric material having barrier properties and poor adhesion to sensitive organs and tissues of the body, such as a stretched polytetrafluoroethylene. The sheet 12 placed on the grid 10 and is connected with it many connective fibers 14 for the formation of the layered structure.
The material used for the connecting fibers 14 may, for example, be monovacancy polypropylene.
Connective fibers 14 are located next to each other, preferably, essentially, with the same gaps 16, constituting not more than 5 mm, preferably not more than 3 mm and even more preferably from 1 to 2 mm.
Each fiber 14 has many places 18 attached to the grid 10, the distance between which is less than 15 mm and preferably not more than 10 mm, so that these segments 20 of the fiber 14 between two adjacent seats 18 are attached to the surface of the grid 10 in the direction of the sheet 12. Preferably all the segments 20 of the fibers 14 have the same length between 5 and 9 mm in such a way that such places 18 attach different fibers 14 are arranged in rows 22, parallel to each other and essentially perpendicular to the adjacent segments 20 of the fibers 14.
Preferably, the diameter of the connecting fibers 14 is larger than the diameter of the fibers is etki 10, so the ratio of these diameters is in the range between 1.1 and 2. Approximately the diameter of the connecting fibers 14 is in the range between 160 and 200 μm, while the diameter of the fibers of the mesh 10 is between 100 and 140 μm.
In addition to snap to the grid 10 of the connecting fibers 14 problemsets to the sheet 12 on the protruding portion of the valve 20, which act as bridges between adjacent seats 18 attachment. The fusion is performed using conventional procedures, for example, through the combined effects of high temperature and pressure during hot rolling. During the last and later when using the connective fibers 14 hold the mesh 10 at a distance from the sheet 12, not allowing gaps, which are essential to the germination of the tissue to be closed, preventing perforation of sheet fiber mesh 10 that will violate its integrity.
In General provides linked the design of the prosthesis, which is resistant to tearing and delamination, as well as elastic and flexible.
It is clear that the scope of the present invention and its variants implementation and design elements can vary significantly in relation to the described and illustrated embodiments which have been given solely as an example, without deviation from the scope of the invention defined by pilage the second formula.
1. Surgical prosthesis for replacement of soft tissues, in particular, for the treatment of hernias and/or abdominal hernias by intraperitoneal injection containing the grid, made from fibers of polypropylene having openings that allow the germination of the fabric, and a sheet made of stretched polytetrafluoroethylene having barrier properties and poor adhesion to sensitive organs and tissues, and the sheet placed on the grid and connected with her for the formation of the layered structure through a set of connective fibers arranged next to each other with a gap constituting not more than 5 mm, and each of the connecting fiber has many places of attachment to the grid with distance between them of not more than 15 mm, and each fiber span between two adjacent seats of attachment is on the surface of the grid facing the sheet, and problable to the sheet.
2. The prosthesis according to claim 1, in which the connective fibers made from polypropylene.
3. The prosthesis according to claim 1 or 2, in which the ratio of the diameters of the connective fibers and the fibers forming the mesh is in the range between 1.1 and 2.
4. The prosthesis according to claim 1 or 2, in which the connective fibers are located next to each other with a gap constituting not more than 3 mm, and preferably between 1 and 2 mm.
5. The prosthesis according to claim 1 or 2, in which the connective fibers in Berlin the wife, essentially, with the same clearances.
6. The prosthesis according to claim 1 or 2, which stretches the connective fibers between two adjacent seats attaching fibers to the grid have a length of not more than 10 mm and preferably between 5 and 9 mm
7. The prosthesis according to claim 1, in which all of these stretches the connective fibers have essentially the same length, so the insertion of various connective fibers are arranged in rows parallel to each other and essentially perpendicular to the adjacent segments of the connecting fibers.
8. The prosthesis according to claim 1 or 2, which has a thickness in the range between 0.4 and 0.6 mm
9. The prosthesis according to claim 1 or 2, in which the sheet is connected with the connecting fibers by hot rolling.
10. The prosthesis according to claim 1 or 2, containing only the mesh and sheets connected by the connecting fibers.
SUBSTANCE: group of inventions refers to surgery and may be used for making external osteosynthesis implants. An osteosynthesis system comprises a piece part on an external surface of which there is a layer of a polymer film in the electret state with the layer of the polymer film made of a fusible element. The group of inventions refers to a method for making the osteosynthesis system involving preparation the layer of the polymer film on an external surface of the piece part by coating the surface of the piece system with a fine fusible polymer powder, fusion thereof on the surface of the piece part and electrostatic charging of the prepared film.
EFFECT: group of invention provides making a uniform coating of the electret layer on the surface of the piece part of the osteosynthesis system firmly attached to the surface of the piece part that enables faster fusion of bone fragments due to electric stimulation and prevented implant corrosion.
10 cl, 1 ex
SUBSTANCE: invention refers to medicine, particularly traumatology and orthopedics, and can find application in treating false joints of long bones. What is described is a method for preparing a non-toxic porous implant of polylactic acid with controlled pore size for building of long bone defects involving melting the polylactic acid granules in a melting pot immersed in thermally stable oil with porogen presented by sodium chloride crystals 100-250 nm to be washed out by aqueous solutions of antiseptics. The implant is prepared with no toxic solvents added and has a pre-set pore diameter.
EFFECT: improved efficiency of the method.
SUBSTANCE: invention refers to medicine. There are described medical implanted devices made of a polymer material and a separation agent wherein the device is a cast reservoir implant, while the separation agent has a molecular weight (M.w.) of min. 1000. The separation agent can be presented by a non-ionic surfactant, such as Bridge-35, polyoxyethylene (20) sorbitan trioleate, Tween 20, Tween 80, vitamin E TPGS, and a mixture of any two or more of them. The hydrated implants can have a surface area of approximately 500 mm2 or more.
EFFECT: used separation agents causes no undesired reactions with cartridge polymer and are safely introducible in a patient.
29 cl, 5 tbl, 3 ex
SUBSTANCE: invention refers to medicine. High antimicrobial activity and desired smoothness providing high thromboresistance are ensured by modifying a product surface, e.g. a polyurethane polyurethane with chlorhexidine and/or its salts with the modification procedure ensured by applying 0.5-4% polyurethane of molecular weight 10000 to 40000 units. in tetrahydrofurane containing chlorhexidine and/or its salts in the amount 0.25-5% (wt) in relation to polyurethane weight that is followed by tetrahydrofurane evaporation.
EFFECT: what is described is a polyurethane catheter with antimicrobial coating, the method for preparing the antimicrobial coating on polyurethane products and the method for producing the polyurethane catheters with the antimicrobial coating.
3 cl, 1 tbl
SUBSTANCE: invention concerns medicine, particularly neurosurgery. What is disclosed is a biocompatible, biostatic, non-toxic, translucent, however imaginable, elastic, strong, reliably fastened duraplasty graft made of a spatially cross-linked polymer prepared by photopolymerisation of methacrylic oligomers. A graft represents an elastic translucent double-layer film with one layers being relieved, while the other one is smooth. The relief is blue-coloured. Such colour provides intraoperative imaging of the graft for a surgeon. At the same time, the unit dimensions of the relief drawing are such that the graft is translucent enough to control the hemostasis efficiency. The layer adjoining the brain is smooth. A roughness degree of the smooth layer ranges within 10 to 20 nanometers to eliminate the adjoining tissue ingrowth into the graft and its opacity on service.
EFFECT: improved graft performance.
7 cl, 3 dwg, 3 ex
SUBSTANCE: invention relates to field of medicine, in particular, to ophthalmology. For intraocular lens applied are soft, with high coefficient of reflection acrylic materials, which contain arylacrylic monomer as single main element-forming monomer, as well as macromer additive for reduction of adhesiveness.
EFFECT: invention ensures application of claimed materials in intraocular lens, as well as other ophthalmological or otolaryngological elements, such as contact lens, keratoprostheses, corneal rings, implants, otolaryngological ventilation tubes and nasal implants.
19 cl, 4 tbl, 10 ex
SUBSTANCE: invention relates to medicine, specifically to surgical material and means for replacement of bone tissue defects. Surgical material contains biodegradable and biocompatible copolymer of 3-hydroxybutyrate and 3-hydroxyvaleriate (3-PHB/3-PHV) and calcium phosphate substances, with the following component ratio, in wt %: copolymer 65-90 and calcium phosphate substances 10-35. According to second version, surgical material, contains biodegradable and biocompatible copolymer, calcium phosphate substances and antibiotic, selected from group which consists of tienam, gentamicin, sulperazon and rubomycinum, with the following component ratio, wt %: copolymer 65-89; calcium phosphate substances 10-35; antibiotic 1-5.
EFFECT: obtaining biodegradable and high-strength surgical material for reconstruction of bone tissue defects of various etiology, which has high osteoinductive and antimicrobial properties.
21 cl, 5 dwg, 3 tbl
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to application in biomedicine, cell technologies, substituting and restorative surgery, in particular for manufacturing matrix-carrier, implanted together with cells into human organism in order to restore functioning of affected organ. Method lies in preparation of solution of polyoxybutirate-polyoxyvalerate (POB/POV) in dichloroethane, after which into solution introduced is icy acetic acid with the following component ratio, g: POB/POV - 1-2, dichloroethane- 10-12, icy acetic acid - 10-15; obtained solution is frozen in form at temperature minus (25-30)°C and sublimation drying of obtained semi-product of matrix is performed in vacuum chamber. Freezing of solution and sublimation drying of obtained semi-product of matrix are performed on padding, made from polytetrafluorethylene fiber and plate from water ice. Thickness of water ice plate is selected on condition of its complete sublimation during drying in vacuum chamber, sublimation drying of matrix semi-product on padding being performed on mesh from plastic threads. Initial pressure in vacuum chamber must be not lower than 100 Torr, and after dichloroethane evaporation from matrix semi-product pressure in vacuum chamber is reduced to ~0.01 Torr. Polymer matrix with bimodal structure of simply connected pores is produced.
EFFECT: simplification and cheapening of technology due to refuse from low temperature of performing vacuum sublimation drying.
7 cl, 4 dwg
SUBSTANCE: invention refers to medicine, specifically to hernia surgery. A synthetic prosthesis made of monofilament fibres with a coat containing 2% chitosan of molecular weight 80000 Da, polyvinyl alcohol, a cephalosporin antibiotic or two compatible or synergistic antibiotics mixed, glycerin in a certain proportions is fixed on an aponeurosis.
EFFECT: use of the invention provides effective antibacterial agents delivery into a plasty zone and prolonged intake into the tissues, applicability of monofilament meshes as explants, reduced pyoinflammatory wound complications and recurrent hernias.
SUBSTANCE: invention relates to a photocurable composition for a three-dimensional article containing the following in wt %: (a) a cation-curable component containing an oxetane compound 35-80; (b) a free-radical active component containing poly(meth)acrylate, which is not dipentaerythritol hexaacrylate 15-60; (c) an antimony-free cationic photoinitiator 0.1-10; (d) a free-radical photoinitiator 0.01-10; (e) one or more additives which increase impact resistance 0.01-40. The photocurable composition can be cured under the effect of actinic radiation and optionally heating, which enables to obtain three-dimensional articles which can be used in various aerospace fields and in methods of casting with consumable patterns. Described also is a method of producing a non-toxic photocurable composition by mixing all components and a method of making a three-dimensional article which is free from antimony.
EFFECT: obtaining solid components having sufficient strength, stable resin viscosity, improved impact resistance and elasticity of components.
25 cl, 45 tbl, 85 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to a material for implanted medical devices. The material represents a conjugate containing a biocompatible, bioabsorbable corrugated PVA-PLA copolymer containing hydrophilic antithrombotic terminal groups of heparin.
EFFECT: corrugated antithrombotic conjugate may be applied on a surface of an implanted medical device to prevent thrombosis in place of arranging the device and counteracting restenosis.
6 dwg, 5 ex
SUBSTANCE: group of inventions relates to neurosurgery. Method of polypyrrole and polyethylene glycol copolymer in plasma includes polymerisation of pyrrole and ethylene glycol monomers by mixing weak flow of their vapour in reactor and application of electric glow discharges, separation of obtained copolymers, subjecting them to 2 or 3 cycles of soaking with acetone, drying copolymers, and mechanical collection of obtained copolymers. Claimed method can be applied for obtaining copolymer of polypyrrole and polyethylene glycol for production of implant, contributing to neuroprotection and recovery of connection in spinal cord after injury.
EFFECT: group of inventions makes it possible to improve conditions for nervous tissue regeneration.
8 cl, 7 dwg
SUBSTANCE: method includes sandblast processing for roughening, etching in acids to remove admixtures and obtain pure titanium on the surface, burning-degassing to remove dissolved gases and reduce tension, single-phase or two-phase anodising (electrochemical oxidising) and burning in furnace to structure crystals and remove bound water from the surface pores. Burning-degassing is carried out in vacuum at temperature 300-770°C, anodising is performed by constant or pulse current (0.5 Hz) in electrolyte solution with forming voltage 25-130 V, burning in furnace is performed at temperature 300-550°C.
EFFECT: method makes it possible to obtain porous nanostructured 1-10 mcm thick oxide film, which consists of open nanotubes of titanium oxides with pore size 40-140 nm of hexagonal or tetragonal order.
6 cl, 3 dwg
SUBSTANCE: wound defect is reduced in layers that involves forming fragments of hernioprosthesis composite coated with a polymer composite to be implanted in any layer of the wound subcutaneously or intraperitoneally. The hernioprosthesis represents a mesh of warp structure of synthetic polymer untwisted pneumatically coupled non thermally fixed complex filaments. The polymer composite consists of a substance of poviargol and medical polyvinylpyrrolidone. Molecular weight of medical polyvinylpyrrolidone makes 13000-90000D at the relation, wt %; 45-55 : 45-55.
EFFECT: method enables studying tissue responses at simulating the environment of replacing hernioplasty with the use of the presented hernioprosthesis showing evident anti-inflammatory, anti-adhesion and reparative action.
9 dwg, 2 ex
SUBSTANCE: invention relates to medical equipment, namely, to surgical instruments and can be applied in implanted devices for providing and supporting lumen of vessel or hollow organ. Implant device for human and animal vessels is made from material with shape memory in form of multi-coil body of rotation, connected with delivering device. Multi-coil body of rotation is made from flat pipe which has multiple perforation. Butt end of pipe are rigidly connected with formation of closed figure from doubled coils, terminal ones of which are connected between each other by rings. Coils are placed one to another without gap. Size of body of rotation in working condition corresponds to size of damaged region of vessel, and has form of cylinder or double-cone figure with the largest diameter in the middle. Terminal doubled coils of multi-coil body of rotation are bent by longitudinal axis with formation of loops. Delivering device for said implant is made in from of flexible catheter with tip, which is equipped with cut for connection with loop of coil of multi-coil body of rotation and face for safe removal of catheter.
EFFECT: reduction of vessel trauma during introduction and placement of claimed implant and safe provision with medicinal substance.
5 cl, 13 dwg
SUBSTANCE: invention relates to field of medicine, namely to surgery, is intended for carrying out tension-free intraabdominal plasty in case of ventral hernias and can be applied widely in surgical treatment of patients with hernias. Endoprosthesis has central and peripheral parts from spatially cross-linked polymer by photopolymerisation of oligomers of methacrylic series. Peripheral part is made in form of monolithic straps connected with central part. Endoprosthesis is strengthened with polypropylene thread. Monolythic straps of peripheral part have holes and the greatest width in places of connection with central part and are located diametrically. Central part forms monolithic system consisting of film and mesh connected to each other on diametrically located with respect to geometric centre of central part double straps, whose middle part forms canal between film and mesh, one surface being smooth and intended for contact with organs of abdominal cavity, the other being rough or containing relief pattern. Along strap polypropylene thread is laced through holes. Near base thread enters canal, is pulled to base of opposite strap, where it is brought out and laced through holes of opposite strap.
EFFECT: invention ensures strength, reliability of fixation of multilayer endoprosthesis for sutureless tension-free intraabdominal plasty cause by ventral hernias, from material which is biostable biocompatible thermosetting plastic.
5 cl, 4 ex, 4 dwg
SUBSTANCE: group of inventions relates to medicine, namely to herniology and plastic surgery of abdomen. Endoprosthesis consists of one-piece sheet of polypropylene or polyvinylidenfluoride mesh endoprosthesis and includes main flap with dimensions with rounded angles and additional in form of wide tape, located near low edge of main flap in transversal to it direction. Method consists of application of endoprosthesis for plasty of umbilical hernias with lifting of muscular-aponeurotic tissues of hypogastric area, whose main flap is fixed supraaponeurotically above sewn hernial ring in umbilical region, and additional - on line bispinalis to aponeurotic tissues in area of upper external spines of iliac bones and aponeuroses of rectus and external oblique muscles of abdomen from one and another sides, performing lifting of musculo-aponeurotic tissues of hypogastric region.
EFFECT: inventions ensure possibility of plasty of umbilical hernias and lifting of musculo-aponeurotic tissues of hypogastric region of abdominal wall in prevention of progressing of anatomical and functional insufficiency of abdominal wall.
2 cl, 1 ex, 3 dwg
SUBSTANCE: group of inventions relates to field of medicine, namely to thoracoscopic surgery, and can be applied in plastic operations on diaphragm in newborns or children of early age. For this purpose applied is implant from porous stretched polytetrafluoroethylene (PTFE), which includes not fewer than 10 layers of more porous PTFE and not fewer than 1 layer of less porous PTFE with total implant porosity being not less than 80% and thickness 1-1.5 mm. Less porous layer has smooth surface and volume share of space of cavities 20-40%, specific surface of space of cavities 0.10-0.35 mcm3/mcm2, average distance between cavities in volume 1-10 mcm, average volume chord 1-5 mcm. More porous layer has rough surface, volume share of space of cavities 80-95%, specific surface of space of cavities 0.75-0.95 mcm3/mcm2, average distance between cavities in volume 30-45 mcm, average volume chord 15-25 mcm. Methods of diaphragm plasty with aplasia of its cupula and with congenital diaphragmatic false hernias include application of patch from said implant. Patch is introduced through thoracoscopic hole in folded form. Patch is placed in such a way that its smooth surface faces abdominal cavity, and rough surface faces pleural cavity.
EFFECT: application of said group of inventions makes it possible to carry out adequate correction of diaphragm cupula in newborns, reduce mortality and development of complications.
5 cl, 2 ex
SUBSTANCE: invention relates to medical equipment, namely to implantable device. Implantable device for application in human and/or animal body aimed at closing or partial closing openings of defects, cavities, canals, ducts in organs, etc. or creation of specified connecting opening between walls, organs, cavities, etc., has bearing structure. Primary form of bearing structure has larger ratio of length to transverse dimension along axis, and secondary form - smaller ratio of length to transverse dimension along axis. Bearing structure includes proximal section and distal section and has form of lattice and/or cloth and/or canvas and/or mesh. At least one section in secondary form contains two parts, one of which is the first to extend from primary form into secondary form and folds in direction from the other section onto the second part, directed towards said other section. Folded part folds back inside implanted device. Said device is used as vessel filter and/or device for removal of foreign particles, or as stent.
EFFECT: invention is suitable for implantation even in those places of human and/or animal body, in which only limited space is accessible for implantation, for instance, into left atrium of the heart, it also has good resistance to undesirable displacement after implantation.
26 cl, 172 dwg
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine. There are described crystallised side-chain polymers which are applicable for various medical purposes. In specific applications, the heavy-atom crystallised side-chain polymers containing are especially applicable. An example of HACSCCP is a polymer which contains a main chain, a set of crystallised side chains and a set of heavy atoms attached to the polymer. In specific configurations, the heavy atoms are found in number which is effective to make the polymer X-ray contrast. A medical device may represent an embolotherapy system. A polymer material containing the SCC polymer is applicable for producing other medical devices, such as stents.
EFFECT: producing the polymer material containing HACSCCP which is applicable for producing the medical device designed for at least partial cavity closure.
26 cl, 1 dwg, 8 ex
FIELD: medicinal equipment.
SUBSTANCE: the present innovation deals with means for restoring and/or keeping the lumen of blood vessel at treating cardio-vascular diseases due to implanting intravascular prostheses. The latter should be designed as a perforated cylindrical tube with grooves of patterned-cellular type which form at initial state periodically repeated rows of oval open rings connected with longitudinal and cross-sectional crosspieces. Repeated rows consist of the cells which in their initial state are of open oval rings the ends of which steadily come into cross-sectional crosspieces to unite these cells into the row. The second row of cells is developed due to mirror image of the first row being connected with the latter with longitudinal crosspieces. Next pairs of cellular rows are connected between each other with longitudinal crosspieces. By another variant for carrying out intravascular prosthesis, the second row of cells should be developed due to shifting the first row for the half of cellular width being connected with it by longitudinal crosspieces, as for the next cellular rows they are connected with longitudinal crosspieces. The method enables to improve flexibility of intravascular prosthesis at initial state and its rigidity at open state.
EFFECT: higher efficiency.
20 cl, 8 dwg