Ophthalmologic lenses for preventing development of myopia

FIELD: physics.

SUBSTANCE: design of contact lenses which are useful for preventing myopia and avoid discomfort when corneal shape changes, as well as undesirable side effects during medication, which is ensured owing to that the lens, according to one of its versions, has an optical zone comprising a central zone having an essentially constant distant vision focal power, a first circular zone which is concentric with the central zone and has positive longitudinal spherical aberration, and a second circular zone which is concentric with the first circular zone.

EFFECT: preventing development of myopia.

16 cl, 2 dwg

 

The technical FIELD TO WHICH the INVENTION RELATES.

This invention relates to ophthalmic lenses. In particular, the present invention provides ophthalmic lenses, suitable to prevent or slow down the progression of myopia.

The LEVEL of TECHNOLOGY

Myopia or nearsightedness affects up to 25% of the population of the United States, and in some regions of the world - up to 75% of the population. In the myopic eye, the shape of the eyeball is elongated, and is included in the eye, light rays focus in front of retina. Conventional treatment of myopia is the statement of corrective lenses. However, the usual corrective lenses do not prevent the development of myopia.

To slow down the progression of myopia - especially myopia in children - it was suggested many ways. These methods include the use of multifocal lenses, the use of lenses with the introduced aberration or lenses that control the aberrations, the use of lenses with offset refractive index, change the shape of the cornea, the training of the eye, and the use of pharmacological therapy.

The use of multifocal lenses, and lenses with the introduced aberration proved to be disadvantageous, since such lenses worsen hyperopia who wears them. Other methods also have disadvantages, including discomfort paragraph and change the shape of the cornea of the eye and unwanted side effects in drug therapy.

BRIEF DESCRIPTION of DRAWINGS

Fig. 1 depicts the front surface of the lens according to the present invention.

Fig. 2 is a graphic optical power of the lenses of the considered examples.

DETAILED description of the INVENTION AND

PREFERRED variants of ITS IMPLEMENTATION

The present invention provides ophthalmic lenses, which essentially prevent the development of myopia, as well as methods of their calculation and fabrication. The discovery underlying the present invention is that the development of myopia can be essentially prevented by using a multifocal lens having a Central region with an optical power for far vision, surrounded by at least one zone having a positive longitudinal spherical aberration.

Under "ophthalmic lens" refers to a contact, intraocular, bill of lading or similar lens. Preferably, the lenses of the present invention are contrasting lenses. Under "optical power for far vision", "the power of the far vision" and "power distance" refers to the value of the refractive abilities required for the correction of visual acuity of distant vision of the person to the desired value. Under "longitudinal spherical aberration" refers to the "dioptric difference in focal distance of the Central and peripheral areas is inzy, calculated as the value of the focal distance in diopters peripheral beam minus the value of the focal distance in diopters paraxial beam. Under "positive longitudinal spherical aberration" refers to the fact that the dioptric difference between the peripheral and the paraxial rays have a positive value.

In the first embodiment, the present invention offers ophthalmic lenses, which have an optical zone, including containing and substantially containing the Central zone, having essentially a constant optical power for far vision, and at least a first annular zone concentric with the Central zone and having a positive longitudinal spherical aberration. In an alternative embodiment, may be formed in the second annular zone concentric with the first annular zone and the second zone may have a constant optical power or gradually decreasing optical power. In yet another embodiment, provides a lens having an optical zone, including containing and substantially containing essentially constant optical power for far vision in the nearest to the center of the optical zone and at least one peripheral area relative to the area of optical power for far vision, with positively the Yu longitudinal spherical aberration.

As can be seen in Fig. 1, the lens 10 has an optical zone 11 and a non-optical zone 14 of the lens. Optical zone 11 is composed of the Central zone 12 and the peripheral area 13. The Central area centered on the optical axis of the lens and has a radius of about 0.5 to 2 mm, preferably about 1 to 1.5 mm, measured from the optical center of the lens. The power of the lens inside the Central zone 12 is essentially constant optical power for far vision and is approximately +12,00 to -12,00 diopters. Because of the addition of positive optical power in the peripheral zone, it may be desirable to introduce excessive correction optical power for far vision in the Central zone, referring to the optical power in addition to that which is necessary for the correction of visual acuity of distant vision of man. The magnitude of excess correction will depend on the diameter of the Central zone 12, and on the value entered is positive spherical aberration. However, as a rule, excessive correction will be approximately from 0.25 to 1.00 diopters.

The peripheral area 13 has a positive longitudinal spherical aberration, which is constantly and gradually increases when moving from the inside edge 14 or the border closest to the optical center of the lens, to the outer limits of 15 peripheral zone 13. Increment longitudinal sferic the Russian aberrations in the peripheral zone 13 may be from about 0.25 to about 2 diopters, and preferably from about 0.5 to about 1.5 diopters at a radius of about 2.5 mm from the optical center of the lens. The peripheral area 13 may have a width of from about 0.5 to about 3.5 mm, preferably from about 1 to about 2 mm.

As shown in Fig. 1, the Central zone 12 and the peripheral area 13 are zones with discrete transition between them. In an alternative embodiment, no discrete transition between a region with essentially constant optical power for far vision and the region with positive longitudinal spherical aberration: both zones with essentially constant optical power for far vision and a positive longitudinal spherical aberration form a single area.

When calculating the lenses of the present invention, a positive longitudinal spherical aberration is introduced without taking into account the aberrations of the human eye. For the purposes of the present invention it is preferable to first determine the spherical aberration of the crystalline lens of the human eye, and then to correct this aberration enter the required spherical aberration. Alternatively, for the value of the spherical aberration can be taken as the value of the average people, equal to 0.1 diopters/mm2. Spherical aberration can be measured by any known and convenient manner, including the use without any limited which I available on the market aberrometers.

For the calculation of the optical zone of the lens according to the present invention can be used with any of a variety of mathematical functions, including, without limitation, the functions describing the sphere, aspheric, spline, bevel, polynomial and similar surface. In a preferred execution of the Central zone is preferably spherical, and between the Central and peripheral zones have a smooth transition. This smooth transition can be defined by mathematical functions that are continuous in value, and have continuous first and second derivatives.

The equation is applicable for use in the calculation of the optical zone of the lens of the present invention, is

(I)

where

y - the distance from the lens center;

the x - deflection value

r is the radius of curvature, and

k is a constant taper: for a sphere = 0, the ellipse -1<k<0; and for the hyperbola k<-1.

For the calculation of the optical zone diameter D of the Central spherical area with a diameter d at-d/2<x<d/2 can be used conical surface by the following equation:

(II)

as for d/2<x<D/2

(III)

The values of deflection at any point can be converted to the radii, and the power of the lens can be calculated on the trail is the fact that the formula:

(IV)

where

P is the optical power, and

n is the refractive index of the lens material.

The optical power for far vision and a positive longitudinal spherical aberration can either work together to treat and, preferably, refers to the front or to the rear surface of the lens or each of them belongs to one of the surfaces of the lens to the front or to the rear. One surface of the lens can determine the optical power for far vision and a positive longitudinal spherical aberration, and the other surface may be spherical, aspherical or include optical power of the cylindrical lens to correct the astigmatism of the person. Normal specialists in this area it is known that variants of a contact lens that has an optical power of the cylindrical lens, the lens will need to enter a stabilizing agent. Appropriate means of stabilization are any, without limitation, known in the art static and dynamic stabilizing means: roll prisms, thin and thick areas, optical washers, etc. and combinations thereof.

In the embodiment, with the Central zone and at least one concentric zone can be entered the second zone concentric with respect to the first Taco the zone. The second concentric area may be essentially constant optical power or, preferably, optical power, gradually decreasing towards the periphery. The second concentric area can be useful for people with large pupils, what are young people in low light. The second zone is preferably begins at a radius of about 3.5 mm and goes up to a radius of about 4.5 mm. In those designs in which the power of the lens from edge to edge of the zone gradually decreases, this decrease is preferably amounts to about half of the total optical power, which is the inner most part of this area. For example, if the lens is in its first concentric zone with a radius of about 2.5 mm has a positive longitudinal spherical aberration in 1.0 diopter, the optical power of the outer part of the second zone will be reduced to a value of about 0.5 diopters. In those versions, in which there is no discrete transition zone with a constant optical power for far vision and the region with positive longitudinal spherical aberration on the periphery, with positive longitudinal spherical aberration can be entered a second area that can have this constant optical power or gradually decreasing optical power. The second input is ereference zone can be useful because it can be used to reduce positive optical power on the periphery of the lens, thereby reducing the deterioration of vision due to such a positive optical power in low light.

Lenses according to the present invention preferably are soft contact lenses made of material suitable for the production of such lenses. Exemplary materials for forming such soft contact lenses include, without limitation, silicon elastomers, silicone macromer, including, without limitation, those disclosed in U.S. patent No. 5371147; 5314960 and 5057578, the full content of which is incorporated into this description by reference, hydrogels, silicone hydrogels and the like materials, and combinations thereof. More preferably, the lens surface was from a siloxane, or from a material with the functionality of the siloxane, including, without limitation, macromer of polymethylsiloxane, methacryloxypropyltrimethoxy siloxanes and mixtures thereof, silicon hydrogel or a hydrogel, such as etafilcon A.

Preferred lesoobrazuyushchim material are polymers of polyuretaanimaaleja, referring to those that have a peak molecular weight between about 25,000 and about 80000 and polydispersity in the range of less the than about 1.5 to less than about 3.5, respectively, and covalently associated with at least one cross-functional team with the ability to establish cross-links. Such material is described in U.S. patent No. 6846892, the full content of which is incorporated into this description by reference. Suitable materials for the formation of intraocular lenses include, without limitation, poly (methyl methacrylate), hydroxyethylmethacrylate, transparent inert plastic, polymers based on silicon and the like, and combinations thereof.

Curing listopadowego material can be performed by any known means, including, without limitation, heat treatment, radiation treatment, electromagnetic effects and the like means and their combinations. The lens is preferably pressed with the use of ultraviolet radiation or radiation of the entire visible range. More precisely the specific conditions suitable for curing the lens material, depend on the selected material and the lenses that you want to create. The polymerization processes of ophthalmic lenses, including, without limitation, contact lenses, are well known. Suitable processes are disclosed in U.S. patent No. 5540410, the full content of which is incorporated into this description by reference.

Contact lenses of the present invention MoE is ut be formed by any conventional method. The optical zone can be, for example, formed by diamond turning or diamond turning can be manufactured forms used for forming lenses according to the present invention. Later, between the forms is filled with a suitable liquid resin, and then pressing and curing the resin, resulting in the formation lens according to the present invention. Alternatively, this area may be formed by diamond turning of lens blanks.

The present invention may be more fully illustrated by the following examples.

Examples

Example 1

The lens according to the present invention has a rear surface with a radius of curvature of 8.8 mm, and the front surface, calculated in accordance with equation II, where k +105; r=1.1 and d=0,75 mm Optical power of the Central zone is -3,00 diopters, and positive longitudinal spherical aberration at a radius of 5 mm is +1 diopters. For the manufacture of lenses first turning using point diamond tool is made of brass bushing, followed by pouring under pressure to obtain from the barrel of lens shapes, and then casting lenses using etafilcon And in accordance with the conventional process for the production of lenses. The solid line in the graph of Fig. 2 shows the optical power optical is Oh area this lens.

Comparative example 1

The lens, made in accordance with the prior art, described in U.S. patent No. 6045578, has a rear surface with a radius of curvature of 8.8 mm and a front surface, calculated in accordance with equation I, where k +is 3.5. The optical power of the Central zone is to 3.00 diopters, and positive longitudinal spherical aberration at a radius of 5 mm is +1 diopters. For the manufacture of lenses first turning using point diamond tool is made of brass bushing, followed by pouring under pressure to obtain from the barrel of lens shapes, and then casting lenses using etafilcon And in accordance with the conventional process for the production of lenses. The dotted line in the graph of Fig. 2 shows the optical power of the optical zone of the lens.

1. Ophthalmic lens containing an optical zone that includes a Central area having essentially constant optical power for far vision, the first annular zone concentric with the Central zone and having a positive longitudinal spherical aberration, and the second annular zone concentric with the first annular zone.

2. Ophthalmic lens according to claim 1, in this case this lens is a contact lens.

3. Ophthalmic lens according to claim 1, in which the second ring is the first area has essentially, a constant optical power.

4. Ophthalmic lens according to claim 1, in which the second annular zone has a gradually decreasing optical power.

5. Ophthalmic lens according to claim 1, in which the optical power for far vision has excessive correction amount from about 0.25 to about 1.00 diopters.

6. Contact lens containing an optical zone that includes a Central area having essentially constant optical power for far vision, and at least a first annular zone concentric with the Central zone and having a positive longitudinal spherical aberration, in which the optical power for far vision has excessive correction amount from about 0.25 to about 1.00 diopters.

7. Contact lens according to claim 6, in which the optical zone further comprises a second annular zone concentric with the first annular zone.

8. Contact lens according to claim 7, in which the second annular zone is essentially constant optical power.

9. Contact lens according to claim 7, in which the second annular zone is essentially a gradually decreasing optical power.

10. Ophthalmic lens containing an optical zone having essentially constant optical power for far vision in the nearest to the center of the optical zone, the first peripheral the ONU relative to the area of optical power for far vision, with a positive longitudinal spherical aberration, and the second peripheral area relative to the first peripheral zone.

11. Ophthalmic lens of claim 10, while this lens is a contact lens.

12. Ophthalmic lens of claim 10, in which the second peripheral area is essentially constant optical power.

13. Ophthalmic lens of claim 10, in which the second peripheral zone has a gradually decreasing optical power.

14. Ophthalmic lens of claim 10, in which the optical power for far vision has excessive correction amount from about 0.25 to about 1.00 diopters.

15. The way to prevent myopia containing phase, which creates ophthalmic lens containing an optical zone that includes a Central area having essentially constant optical power for far vision, the first annular zone concentric with the Central zone and having a positive longitudinal spherical aberration, and the second annular zone concentric with the first annular zone.

16. The way to prevent myopia containing phase, which creates a contact lens containing an optical zone that includes a Central area having essentially constant optical power for far vision, and at least a first annular zone, close tricou relative to the Central zone and having a positive longitudinal spherical aberration, when this optical power for far vision has excessive correction amount from about 0.25 to about 1.00 diopters.



 

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