Device to deliver ultracold neutrons along flexible neutron guides

FIELD: power engineering.

SUBSTANCE: device has a stationary vacuumised neutron guide made in the form of a stainless steep pipe, nickel or copper. The device is additionally equipped with a section of a neutron guide made as a flexible polyvinyl chloride tube, the inner wall of which has mirror surface. Values of average roughness of the inner wall of the flexible polyvinyl chloride tube do not exceed the length of the ultracold neutron wave length.

EFFECT: reduced losses of low energy neutrons during transportation, capability of delivering them into hard-to-access areas.

8 cl, 5 dwg, 1 tbl

 

The technical FIELD

The invention relates to the field of nuclear physics, and more specifically to methods for delivery of low-energy neutrons from the neutron source to the objects of the research or experimental installations.

The present invention can be used for transporting low neutron energies, including ultracold neutrons in remote places through the curved channels of complex configuration or when conducting neutron capture therapy of cancer, localized in body cavities or internal organs.

PRIOR art

The guide used for output neutrons from the active zone of the nuclear reactor or the target accelerator for biological protection in the experimental hall and the Department of neutrons of low energy gamma-rays from the direct beam.

Ultracold neutrons (UCN) are neutrons with energies of ~10-7eV, with a speed of 10 m/s or less and a wavelength of from several hundreds to thousands of angstroms. One of the remarkable features of UCN is their ability to experience total reflection from the surface of condensed matter at all angles of incidence. The phenomenon of total reflection of UCN has been demonstrated in numerous experiments.

Ultracold neutrons intensively use the I in fundamental physics and, perhaps could be used in surface physics and nano-particles, neutron optics and other applications of neutron physics.

Threshold energy for total reflection of neutrons from the surface at all angles of incidence is determined by the expression:

µ is the magnetic moment of the neutron; ρ is the density of nuclei; b is the coherent scattering length; m is the mass of the neutron; h - Planck constant; magnetic induction; (±) - for neutron spin parallel and anti-parallel direction relative to the Century

When b>0 neutron originating from vacuum environment, meets positive barrier height of U. For most nuclei b>0, and only for some isotopes of nuclei (Li, Mn, Ti, V) b<0. If the energy of the neutron is less than Egthe neutron is reflected and does not pass the boundaries. For almost all substances Eg~10-7eV. The values of Egand critical speeds for some materials are given in the table.

The values of Egand critical speeds for some materials
SubstanceEg(10-7, eV)vgm/sSubstanceEg10 -7, eV)vgm/s
H2About-0,146-Al0,5413,22
Polyethylene-0,070-Ti-0,500-
Be2,5006,90Mn-0,680-
C (graphite)1,750of 5.83Gr. steel1,8206,05
Mg0,5953,37Cu1.7205,70

One of the main parameters characterizing the neutron guide is its bandwidth, i.e. the ratio of the neutron flux at the exit of the neutron guide to the flow I is de. Loss of neutrons depend on the quality of the surface of the neutron guide, the presence of contamination, the vacuum level, diameter and length of the neutron guide. Obviously, weakening the stronger, the more rough and dirty wall of the neutron guide and the worse the vacuum inside it. Currently, the typical loss density of neutrons in the neutron guide is more than 10 times [V.V.Nesvizhevsky Nuclear Instruments and Methods in Physics Research A 557 (2006) 576-579].

Thus, ultimately, transport of ultracold neutrons is determined by the interaction of neutrons with the wall. It is known that transport of neutrons of low energy long distances necessary to guide high reflectivity of the walls, a sufficiently large boundary energy and low loss factor in collisions with the walls. As practice shows, the most smooth for UCN reflection surface gives electrochemical polishing. However, achieving high specularity of the walls to the metal guide is a difficult technological task and it is not always possible, especially for complex configuration guide.

There is a method of transport of ultracold neutrons in the guide, made of chemically polished copper tube or stainless steel [Vukoslavcevic "Physics of ultracold neutrons". M., Nauka, 1986]. Typical n is atronaut UCN is a cold polished pipe of circular cross section with a diameter of 5-10 cm and a length of 10-20 m The diameter of the neutron guide is usually determined by geometrical constraints in the vicinity of the source (reactor core or the target of the accelerator). Length is determined by the minimum adequate distance between the neutron source and experimental setup.

The main reason for the loss of UCN in the neutron guide is their diffusion, i.e. not mirror the neutron scattering on the walls. The probability of diffuse scattering of waves on a rough surface is given approximately by the relation ~(∆D/λ)2where ∆ d is the average roughness of the surface and λ is the wavelength of ultracold neutron, which is 10÷20 nm. Thus, a high probability of specular reflection (much better than 1%) is only possible, if the roughness of the wall is less than ~1 nm.

On the other hand, there was adequate surface roughness for the UCN guide used for several decades in many research centers. Attempts to use a glass or silicon, the guide did not succeed - these materials have very low cutoff energy Eg. Any coating substance with a higher Egsuffers from the worst of the mirror surface properties, as well as from minor defects in the coatings, which are important because UCN with energies higher than the threshold energy of MaterialScience, with high probability are lost through any defect coverage. In addition, glass can not withstand high doses of radiation inside a nuclear reactor.

Thus, the search for materials with high specular reflection and high boundary energy, for UCN is an important task. A good candidate for the material of the neutron guide UCN - beryllium, which can be quite polished and aligned, rigid, in particular, does not form sharp edges if the fracture (broken edge would lead to diffuse scattering), radiation resistant and has a fairly high threshold energy (~150 nm)to use it without any covering. Otherwise, the resistance of any coatings radiation would be weak and never guaranteed. Finally, low loss of UCN in beryllium traps has been proven in experiments where low loss have been achieved without pre-treatment or cooling surface, as is usually done for other materials to improve the throughput of the neutron guide.

A prototype of the selected RF patent №2313377 "Method for making a neutron-capture therapy of cancer" (IPC A61N 5/10 (2006.01). G21K 5/00 (2006.01), G21G 4/02 (2006.01), G21G 1/06 (2006.01). Application: 2005135228/14, 15.11.2005).

In the proposed method of ultracold neutrons removed from cryogenic neutron Converter I have cluster of the reactor and transported to the affected organ or tissue by vacuum neutron guide, the end part of which is made in the form of a flexible catheter. A flexible catheter is a thin-walled metal corrugated bellows tube type. At the end of the catheter is a thin, transparent window with b<0, through which ultracold neutrons come into a malignant tumor.

However, the method of delivery of ultracold neutrons, selected as a prototype, has several disadvantages, among which may be mentioned the following:

the inner wall of the corrugated tube of the catheter has no specular reflection of neutrons due to surface irregularities, which inevitably leads to the loss of neutrons during transportation and to reduce the overall bandwidth of the neutron guide;

- high elasticity metal wall of the catheter does not provide the necessary flexibility, which complicates the introduction of the catheter into the narrow channels of a complex configuration with turns at large angles.

DISCLOSURE of INVENTIONS

The objective of the invention is to reduce losses of neutrons of low energy, including ultracold neutrons during their transportation through the channels of complex configuration and delivery in hard to reach areas and internal cavities, as well as providing the possibility of using for the purpose of plastic materials having high flexibility.

To achieve these objectives is proposed to use a flexible guide, made of polyvinyl chloride tube, the inner wall of which has a mirror surface, and the average roughness less than the wavelength of ultracold neutrons.

As the material of the neutron guide are encouraged to use the polymer polyvinyl chloride (chemical formula [-CH2-CHCl-]n) with a density of 1.4 g cm-3and molecular weight in the range 30000-100000 Amu Length of the coherent scattering of carbon, hydrogen and chlorine, respectively bH=-3,74 10-13cm, bC=6,65·10-13cm, bCl=9,58·10-13see Boundary energy polyvinyl chloride equal to 39.7·10-9eV, and the value of the boundary velocity of 2.8 m·s-1.

Polyvinyl chloride (PVC) is a thermoplastic polymer of vinyl chloride. Different chemical resistance to alkalis, mineral oils, and many acids and solvents. PVC is almost amorphous polymer. This is due to the high rigidity of the chain, with a huge segment of the molecule.

Physical causes of secularity PVC associated with the molecular characteristics of the surface layer of this polymer. The presence of physical and mechanical strength of the intermolecular coupling, due to the presence of electronegative chlorine, determines the high strength PVC, chemical resistance and low surface roughness.

The reflectivity of the surface of the PVC can b is to be still further enhanced by applying a thin layer of liquid hydrogen-free of photopolymer fomblin, composed of only the atoms C, O, F and with a higher boundary energy and a smaller absorption coefficient than polyvinyl chloride. Loss of ultracold neutrons in the collision with the surface of fomblin is mainly caused by inelastic scattering in the region of thermal neutron energies. The probability of loss in a single collision with the wall is ≈10-5[Serebrov A.P. the lifetime Measurement of the neutron using a gravitational trap ultracold neutrons. The success of the physical Sciences. Volume 175, No. 9, 2005, str-924].

Flexible PVC tubing allows without significant losses to deliver the SOUP from the source in arbitrary directions. For example, such tubes can be used as medical catheters for the purpose of neutron capture therapy (NRT) of malignant tumors, where it is critical to have the opportunity to sum up the neutrons to the affected organs or tissues. This opens up new possibilities NRT in part to the treatment of malignant tumors localized in body cavities or organs. It is, first of all, cancer foci in the lungs of various etiologies, cancers of the esophagus, larynx, internal organs of the abdominal cavity malignant neoplasm of bone in the sinus, skin lesions mocrowave medicines are available with 10In that can accumulate in the plaques of the vessels, it will be possible the application of UCN in the treatment of sclerotic lesions of the vessels that while it is almost impossible in traditional technologies NRT due to significant radiation damage of the vascular wall and blood cells. Perhaps technology NRT using ultracold neutrons will become a new stage in the development of cellular NRT with greater therapeutic efficacy compared to traditional. It is important that in these therapies, in contrast to traditional NRT, in therapeutic beam UCN no accompanying background γ-radiation and fast neutrons reactor, causing harmful irradiation of healthy tissues.

Thus, the technical problem is solved using the proposed combination of essential features.

Device for delivery of low neutron energies, including ultracold neutrons with stationary vakuumirovaniya the neutron guide, made in the form of a tube of stainless steel, Nickel or copper, and

the device is further provided with a plot of the neutron guide, made in the form of a flexible PVC tube, the inner wall of flexible PVC tubing has a smooth surface with an average roughness of the inner wall of flexible PVC tubing does not exceed d the ins waves of ultracold neutrons thus

as a material part of the neutron guide is used, the polymer is polyvinyl chloride, having the chemical formula [-CH2-CHCl-]n;

- the inner surface of the flexible PVC tube covered forosamine the polymer fomblin;

- the inner surface of the flexible PVC tubing is made with an average roughness less than 1 nm;

- flexible PVC tube attached to a stationary neutron guide through the input nozzle;

- the inner surface of the flexible PVC tube covered forosamine the polymer fomblin YH VAC 18/8, with boundary energy of 1.06·10-7eV.;

- the inner surface of the flexible PVC tube covered forosamine the polymer fomblin in the form of a layer with a thickness of 0.05÷0,1) mm;

- flexible PVC tube has an internal diameter of 6 to 8 mm

An EXAMPLE of carrying out the INVENTION

As an example illustrating the method of delivery of ultracold neutrons through a flexible guide PVC, below conducted research on the UCN beam high flux reactor HFR Institute. M.laue and Plongeon (Grenoble, France).

Schematic diagram of the experimental setup is shown in figure 1. Ultracold neutrons with energy (5,2÷3,6)·10-7eV horizontal stoichiometric is the gadfly 1 and vertical neutron guide 2 length N=160 cm from the source was received in a short neutron guide 3. The diameter of the guide, made of stainless steel was 7 see

Rising in the neutron guide 3, the neutron reduced energy up (0÷2,0)·10-7eV and acted in a flexible neutron guide 4 of PVC tube. Investigated in the experiments of the tube had an inner diameter of 6 to 8 mm. UCN Flux at the exit of the tube 4 has entered into the transition chamber 5 and measured gas proportional detector 6 on the basis of isotope3He with aluminum entrance window with a diameter of 9 cm

The wiring diagram of the detector and the input of the pipe with PVC tube on a larger scale is shown in figure 2.

The ends of the PVC tube 4 vacuum tightly stretched on the outlet of the upper neutron guide 7 and the inlet of the detector 8. The vacuum in natronomonas system and the PVC tubes were maintained at the level of 10-3mm Hg

The length of the branch pipes 3 cm, inner diameter equal to the diameter of the investigated tubes. UCN through pipe detector fell in volume transition chamber 5 from stainless steel. If the energy of the UCN was larger than the bounding energy of aluminum, equal 52,0·10-9eV and, accordingly, the speed is more than 3.2 m·s-1the neutrons were recorded. Thus, the detector 6 registered neutrons with a velocity in the interval (3,2÷6,3) m·s-1. The probability of UCN from the transition chamber 5 in vinylchloride pipe 4 is negligible. To measure the input stream of neutrons I0coming in the investigated flexible tube, the inlet and the outlet of the detector was connected closely, and the vacuum was provided by a short length of pipe attached to the pipe (L=0).

As the experiments showed, the transmission pipes essentially depends on the shape of their cross section, changing the length from circle to ellipse. The best results were obtained for PVC pipe, the cross section of which along the entire length was close to the circumference of the cylindrical tube).

Figure 3 shows the dependence of the transmittance of ultracold neutrons PVC tube with an inner diameter of 8 mm from the length (the bottom line is PVC pipe, the top of the PVC pipe with a coating of the inner surface forosamine the polymer fomblin). Here W=I(L)/I0where l(L) is the neutron flux at the exit of the tube diameter d of 8 mm and length L, having changed from 4 cm to 290 see the Ratio L/d was reached (5÷360).

You can see that after the production of a tube of length L=4 cm, the transmittance decreases sharply from 1 to 0.36. When further increasing L, the transmittance decreases slowly, reaching W=0,07 when L=290 see Qualitatively the result can be explained as follows. When injected into the pipe UCN with the first collision with the wall with a radial component with which oresti V r>2.8 m·s-1penetrate into the wall of the tube and leave its volume, experiencing inelastic scattering and capture of the polyvinyl chloride. On the section of a tube of length L>4 cm main part of such neutrons leaving the volume of the tube. Neutrons with a radial component of Vr<2.8 m·s-1reflected from the walls, subject to the tube. Due to the specularity of reflection and cylindricity of the tube, the magnitude of the radial component of velocity Vrsaved from one collision to another. Further weakening of the flow of UCN in the interval L=(4÷290) cm, may be inferred from podbarany absorption UCN reflection or weak deviations shape from the cylindrical tube.

The following measurements of the same polyvinyl chloride tube was covered from the inside forosamine the polymer fomblin YH VAC 18/8, with boundary energy of 1.06·10-7eV, which corresponds to the boundary velocity 4,56 m·s-1. Photopolymer was applied in a layer with a thickness of 0.05÷0,1) mm measurement Results of the transmittance of the tubes, covered with photopolymers shown in Figure 3 above. You can see that after setting the pipe with L=4 cm transmittance W=0.98 and decreases to 0.75 for L=290 see an Increase in the marginal rate reflecting layer to 4.56 m·s-1led to the fact that almost all the neutrons of the incoming flow was zakhvachennymi tube and, specularly reflected, apply to the exit of the neutron guide. The relative weakening of the UCN flux with increasing length was significantly less. This can be explained by the fact that after covering tube photopolymers decreased losses of UCN in podbiraem reflection, and the heterogeneity of the cross-section of steel pipe less impact on the process of UCN distribution.

Figure 4 shows the values of the transmittance of a polyvinyl chloride tube with a diameter of 8 mm and a length of 190 cm, depending on the spatial configuration. The characteristic radii of the bends was (10-20) see the transmittance of the tube is determined by the expression T=I(direct)/I(configuration)where I(direct)the UCN flux at the exit of the straight tube, Iconfigurationthe UCN flux at the exit of this tube, but curved in a given configuration.

From Figure 4 it is seen that the curves of the tube affect the transmission slightly. Even triple the turnover of the tube leads to a weakening of the output stream only 45%. Similar results were obtained for a tube length of 290 cm, covered inside photopolymers fomblin. The values of T for tube length 290 cm is shown in Figure 5.

The experimental results confirmed the high reflectivity of the surface of the PVC pipe. The reflectivity of the surface increases with the application of a thin layer of liquid photopolymer with the more high boundary energy and lower absorption coefficient. The surface of this quality provides the transmission of UCN when the ratio L/d=360 level (70-75)%. Thus, when the diameter PVC neutron guide 8 mm possible efficient transport of UCN at the distance of 30 m from the neutron source.

Flexible PVC tubing allows without significant loss of bandwidth quickly and efficiently to deliver the UCN source in arbitrary directions. Such tubes can be used as medical catheters for the purpose of neutron-capture therapy of malignant tumors.

1. Device for delivery of low neutron energies, including ultracold neutrons with stationary vakuumirovaniya the neutron guide, made in the form of a tube of stainless steel, Nickel or copper, wherein the device is further provided with a plot of the neutron guide, made in the form of a flexible PVC tube, with the inner wall of flexible PVC tubing has a smooth surface with an average roughness of the inner wall of flexible PVC tubing does not exceed the wavelength of ultracold neutrons.

2. The device according to claim 1, characterized in that, as a material part of the neutron guide is used, the polymer is polyvinyl chloride, having the chemical formula [-CH2-CHCl-]n.

3. The device according to claim 2, characterized in that inside NAA surface of the flexible PVC tube covered forosamine the polymer fomblin.

4. The device according to claim 1, characterized in that the inner surface of the flexible PVC tubing is made with an average roughness less than 1 nm.

5. The device according to claim 1, characterized in that the flexible PVC tube attached to a stationary neutron guide through the input socket.

6. The device according to claim 3, characterized in that the inner surface of the flexible PVC tube covered forosamine the polymer fomblin YH VAC 18/8, with boundary energy of 1.06·10-7eV.

7. The device according to claim 1, characterized in that the inner surface of the flexible PVC tube covered forosamine the polymer fomblin in the form of a layer with a thickness of 0.05÷0,1) mm

8. The device according to claim 1, characterized in that the flexible PVC tube has an internal diameter of 6 to 8 mm.



 

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3 ex

FIELD: medicine.

SUBSTANCE: invention refers to medical equipment, and can be used in hadron radiation therapy of malignant tumours. The method involves the pre-radiation preparation consisting in fixing a patient, evaluating the topographometric parameters of the malignant tumours, developing a conformal irradiation session. Conducting the conformal irradiation session is combined with regulating a radiation dose received by the malignant tumour, adjusting the acceptable values of irradiation source parameters, a radiation background, temperature values of various places of the irradiation source and magnetooptical chain of beam delivery of the malignant tumour. During the pre-radiation preparation and conformal irradiation session, the patient is fixed in an identical adjusted position, the topographometric parameters of the malignant tumours are evaluated, and a hadron beam is delivered to the malignant tumour of the patient in the form of an enable pulse of beam delivery to the gastric tumour during a respiratory pause of the patient in the absence of cardiac beat pulse wave peak with a constant size of a thorax. A complex comprises a charged particle generator connected through a multichannel magnetic radiation transporter to a multichannel radiation therapeutic apparatus supplied with radiating heads, a cryogenic station, a gas refrigerator unit, a control and alarm equipment, and also a digital control means subsystem. The charged particle generator is supplied with accelerating and deflecting magnets, while the multichannel magnetic radiation transporter comprises transporting and deflecting magnets, and the irradiating heads of the radiation therapeutic apparatuses have scanning and focusing magnets. All magnetic windings are superconducting and have the cooling channels connected by a gas-vapour mixture of the cooling agent with the cryogenic station, and by a gas cooling agent - with the gas refrigerators. In addition, the complex accommodates physiological feedback means comprising time respiratory evaluators in the form of heat-sensitive sensors or optical electronic sensors reacting on the thorax size variation in respiration, and cardiac beat pulse wave in real time located on the patient's body.

EFFECT: use of the invention allows more precise irradiation of the gastric tumour during respiration not injuring the adjacent healthy tissues and organs.

5 cl, 2 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to oncology, and can be applied in treating rectal cancer (RC). A method involves the intrarectal introduction of 5-fluorouracil and metronidazole in a composite mixture containing sodium alginate and 2 % dimethylsulphoxide, beam therapy, local SHF hyperthermia followed by a surgical intervention. 5-fluorouracil is introduced daily from the 1st to 5th day, and from the 3rd and 5th days of the therapeutic course, 5-ftoruratsil is introduced in a combination with metronidazole with the exposition 5 hours, and the surgical intervention follows in 2-3 weeks after the therapeutic course.

EFFECT: use of the invention allows increasing recurrence-free survival rate in the RC patients.

2 ex

FIELD: medicine.

SUBSTANCE: invention refers to medical equipment, and can be used in hadron radiation therapy of malignant tumours. The method involves the pre-radiation preparation consisting in fixing a patient, evaluating the topographometric parameters of the malignant tumours, developing a conformal irradiation session. Conducting the conformal irradiation session is combined with regulating a radiation dose received by the malignant tumour, adjusting the acceptable values of irradiation source parameters, a radiation background, temperature values of various places of the irradiation source and magnetooptical chain of beam delivery of the malignant tumour. During the pre-radiation preparation and conformal irradiation session, the patient is fixed in an identical adjusted position, the topographometric parameters of the malignant tumours are evaluated, and a hadron beam is delivered to the malignant tumour of the patient in the form of an enable pulse of beam delivery to the oesophageal carcinoma during a respiratory pause of the patient in the absence of cardiac beat pulse wave peak with a constant size of a thorax. A complex comprises a charged particle generator connected through a multichannel magnetic radiation transporter to a multichannel radiation therapeutic apparatus supplied with radiating heads, a cryogenic station, a gas refrigerator unit, a control and alarm equipment, and also a digital control means subsystem. The charged particle generator is supplied with accelerating and deflecting magnets, while the multichannel magnetic radiation transporter comprises transporting and deflecting magnets, and the irradiating heads of the radiation therapeutic apparatuses have scanning and focusing magnets. All magnetic windings are superconducting and have the cooling channels connected by a gas-vapour mixture of the cooling agent with the cryogenic station, and by a gas cooling agent - with the gas refrigerators. In addition, the complex accommodates physiological feedback means comprising time respiratory evaluators in the form of heat-sensitive sensors or optical electronic sensors reacting on the thorax size variation in respiration, and cardiac beat pulse wave in real time located on the patient's body.

EFFECT: use of the invention allows more precise irradiation of the oesophageal carcinoma during respiration not injuring the adjacent healthy tissues and organs.

5 cl, 2 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medical equipment, and is used in hadron radiation therapy of malignant tumours, more specifically in breast cancer treatment by carbon proton and ion beams. The method involves the pre-radiation preparation consisting in fixing a patient, evaluating the topographometric parameters of the malignant tumours, developing a conformal irradiation session with considering the topographometric parameters of the malignant tumours, radiation-critical adjacent tissues and bodies, conducting the conformal irradiation session with regulating a radiation dose received by the malignant tumour, adjusting the acceptable values of irradiation source parametres, a radiation background, temperature values of various places of the irradiation source and magnetooptical chain of beam delivery of the malignant tumour. During the pre-radiation preparation and conformal irradiation session, the patient is fixed in an identical adjusted position, the topographometric parameters of the malignant tumours are evaluated, and a hadron beam is delivered to the malignant tumour in the form of an enable pulse of beam delivery to the breast cancer during a respiratory pause of the patient in the absence of a cardiac beat pulse wave peak with a constant size of a thorax. A therapeutic proton-ionic complex comprises a charged particle generator connected through a multichannel magnetic radiation transporter to a multichannel radiation therapeutic apparatus supplied with radiating heads, a cryogenic station, a gas refrigerator unit, a control and alarm equipment, and also a digital control means subsystem with its driving output connected to an beam delivery enable input of the charged particle generator. The charged particle generator is supplied with accelerating and deflecting magnets, while the multichannel magnetic radiation transporter comprises transporting and deflecting magnets, and the irradiating heads of the beam therapeutic apparatuses have scanning and focusing magnets. All magnetic windings are superconducting and have the cooling channels connected by a gas-vapour mixture of the cooling agent with the cryogenic station, and by a gas cooling agent - with the gas refrigerators. In addition, the complex accommodates physiological feedback means comprising time respiratory evaluators in the form of heat-sensitive sensors reacting to cold air in inhalation and on hot air in exhalation or optical electronic sensors reacting on the thorax size variation in respiration, and cardiac beat pulse wave in real time located on the patient's body.

EFFECT: use of the invention allows more precise irradiation of the breast cancers during respiration not injuring the adjacent healthy tissues and organs.

5 cl, 2 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medical equipment, and can be used in hadron radiation therapy of malignant tumours. The method involves the pre-radiation preparation consisting in fixing a patient, evaluating the topographometric parameters of the malignant tumours, developing a conformal irradiation session. Conducting the conformal irradiation session is combined with regulating a radiation dose received by the malignant tumour, adjusting the acceptable values of irradiation source parameters, a radiation background, temperature values of various places of the irradiation source and magnetooptical chain of beam delivery of the malignant tumour. During the pre-radiation preparation and conformal irradiation session, the patient is fixed in an identical adjusted position, the topographometric parameters of the malignant tumours are evaluated, and a hadron beam is delivered to the malignant tumour of the patient in the form of an enable pulse of beam delivery to the tracheal tumour during a respiratory pause of the patient in the absence of cardiac beat pulse wave peak with a constant size of a thorax. A complex comprises a charged particle generator connected through a multichannel magnetic radiation transporter to a multichannel radiation therapeutic apparatus supplied with radiating heads, a cryogenic station, a gas refrigerator unit, a control and alarm equipment, and also a digital control means subsystem. The charged particle generator is supplied with accelerating and deflecting magnets, while the multichannel magnetic radiation transporter comprises transporting and deflecting magnets, and the irradiating heads of the radiation therapeutic apparatuses have scanning and focusing magnets. All magnetic windings are superconducting and have the cooling channels connected by a gas-vapour mixture of the cooling agent with the cryogenic station, and by a gas cooling agent - with the gas refrigerators. In addition, the complex accommodates physiological feedback means comprising time respiratory evaluators in the form of heat-sensitive sensors or optical electronic sensors reacting on the thorax size variation in respiration, and cardiac beat pulse wave in real time located on the patient's body.

EFFECT: use of the invention allows more precise irradiation of the tracheal tumour during respiration not injuring the adjacent healthy tissues and organs.

5 cl, 2 dwg

FIELD: medicine.

SUBSTANCE: invention refers to radiation therapy apparatuses. An implant is designed as modular pairs or modules making a chain; the modular pairs are formed by two portions. The implant comprises a guide catheter provided with an arrester. The guide catheter can be inserted or removed through a channel located in the modular pairs or in the modules. Either the portions of the module, or the modular pairs, or the modules have elastic elements which are coupled with a peripheral circle and with the channels of the portions of the module or the modules.

EFFECT: use of the invention allows selecting a radiation dose and adapting it for a specific geometrical configuration in a resection cavity.

22 cl, 14 dwg

FIELD: medicine, oncology.

SUBSTANCE: the present innovation deals with treating patients with uterine cervix cancer with relapses in parametral fiber and in case of no possibility for radical operative interference and effect of previous radiation therapy. During the 1st d of therapy one should intravenously inject 30 mg platidiam incubated for 1 h at 37 C with 150 ml autoblood, during the next 3 d comes external irradiation per 2.6 G-r. During the 5th d of therapy one should introduce the following composition into presacral space: 60 ml 0.5%-novocaine solution, 1 ml hydrocortisone suspension, 2 ml 50%-analgin solution, 1 ml 0.01%-vitamin B12 solution, 1.6 g gentamycine, 800 mg cyclophosphan, 10 mg metothrexate. These curative impacts should be repeated at mentioned sequence four times. The method enables to decrease radiation loading and toxic manifestations of anti-tumor therapy at achieving increased percent of tumor regression.

EFFECT: higher efficiency of therapy.

1 ex

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