Mineral nutrient salt stabilised with amino acids and/or ammonium salt, product and food supplement containing such salt and its production method

FIELD: food industry.

SUBSTANCE: invention refers to chemistry and food industry. Proposed is a mineral nutrient salt stabilised with amino acids and/or an ammonium salt. The salt is produced with organic acids anions or inorganic anions and metal cations bound to the amino acids and/or the ammonium salt. The metal cations are bound via ionic linkage to the anions and via covalent semi-polar linkage - to the amino acids amino group and/or the ammonium salt. The salt is represented by its general formula: {[Ac]n-·Men+ ← n [amino acid and/or ammonium salt]}·x H2O, where ← is covalent semi-polar linkage. Additionally proposed are a product and a food supplement containing such salt and a method for its production.

EFFECT: invention enables production of salts possessing improved taste and better solubility in water which renders them more biologically available.

16 cl, 2 dwg, 2 ex

 

The scope of the invention

This invention relates to the field of chemistry and more particularly to chemistry, and applied food and dietary supplements. The invention provides new compounds which are mineral salts stabilized with amino acids and/or ammonium salts, with higher solubility in water, better organoleptic properties and greater bioavailability.

Description of the prior art,

The importance of an appropriate diet, which is in addition to the requirements of essential minerals for animals as for people, well validated in the literature. There are numerous works in which presents problems caused by lack of essential minerals and how these problems are resolved by taking them inside. Minerals are needed for the processes of cellular metabolism as cofactors of the enzyme, as part of the chain of electron transfer and other

They consist of groups of nutrients (about 30), which does not provide energy to the body, but have important regulatory functions, as well as structural function, as they are part of many tissues. They are components of bones and teeth, they regulate the composition of the intracellular and extracellular fluids and are what actu enzymes and hormones, essential molecules for life. There are two large groups: macronutrients, which are so named because they must be supplied in large quantities by the diet or because they are in higher concentrations in the tissues of the body: calcium, phosphorus, magnesium, sulfur, potassium, sodium and chlorine. Others, such as cobalt, copper, iron, chromium, fluoride ion, manganese, selenium and zinc, are also necessary, but in lower quantities; therefore, they are called micronutrients or trace elements.

Thus, it is important to provide appropriate levels of amino acids. Amino acids are the basis of proteins. The food that we eat provides us with protein. However, such proteins are usually not absorbed in such compositions, but they are after cleavage (hydrolysis or decomposition), caused by the process of digestion pass through the intestinal wall in the form of amino acids and peptides with a short chain that is known as "intestinal-hepatic circulation. Such substances are included into the bloodstream and from which they are delivered to the tissues that need them for the formation of proteins that are consumed throughout the life cycle. It is well known that, of the 20 known protein 8 amino acids are essential (or indispensable) for human life, and 2 are "half-required". These 10 amino acids which should be included in the body when consumed daily food, and, mainly, when the body needs them most: when the dysfunction or disease. Essential amino acids, which are the most problematic are tryptophan, lysine and methionine.

They are usually lacking in populations in which the basis of food are cereals and tubers. Lack of essential amino acids affects more children than adults. It is worth mentioning that if one of them (essential amino acids) is present, it will be impossible to synthesize any of the proteins that require the specified amino acid. This fact can cause different types of malnutrition, depending on which amino acids are limited.

Notable is the fact that if for a suitable nutrition diet should have sufficient levels of essential metals, most of the ways in which nature found these metals may not be applied, taking into account the fact that for most compounds containing the metals, there is no way that they can be absorbed, distributed and applied in an effective way.

Salt mineral nutrients of mineral or organic acids, which are used to combat deficiency syndromes in humans, animals or vegetables, have some limitations to their application is, such as metallic taste, which limits their reception, and/or low solubility in water, which limits their absorption and bioavailability. Absorption of essential elements depends, in most cases, the solubility of the salts applied. Thus, as a rule, the higher the solubility, the greater the absorption.

Other suitable factor is a biological property of the element, just absorbed. This means that the element must participate in the same metabolic pathways, known as salt, as suggested by reference.

The products formed from salts of organic or mineral acids, which are derived from amino acids and/or ammonium salts, form a product with a more pleasant taste and high solubility.

You have developed various complex compounds of essential metals and amino acids at a ratio of 1:1 to increase the biological availability of these metals after their use (see patent No. 3941818, 3925433, 3950372, 4021569 and 4067994). In these patents educated connections form chelates. A chelate is a very simple expression, which means the formation of rings, including metal center in coordination compounds. The formation of such compounds occurs when the ligand with more than one "memory is om" is coordinated to the same metal centre.

Salts of this invention are not chelate compounds of the above-mentioned systems, but they are stable semipolar communication and they have a very high solubility (solutions, more than 50% by weight or 400 g per liter of water), which makes them easy to add to food without changing its water volume.

Brief description of the invention

Thus, the purpose of this invention to provide products of mineral salts or organic or inorganic acids, which are associated with amino acid and/or ammonium salts which have the General formula or structure:

{[AC]n·Men+← n [Amino acid/ammonium salt]}·xH2Oh,

where ← represents semipolar covalent bond,

and have a better taste and more soluble in water, which makes them more bio-available.

Another purpose of this invention is the provision of salts of mineral nutrients stabilized with amino acids and/or ammonium salt, and the metal "Men+" selected from the group which consists of the following cations: calcium, magnesium, zinc, iron, copper, manganese, sodium, potassium, Nickel or cobalt.

Also the purpose of this invention is the provision of salts of mineral nutrients stabilized with amino acids and/or ammonium salt, where the acid is selected from g is uppy, consisting of fumaric acid, malic acid, hydrochloric acid or sulfuric acid, pure or associated.

Similarly, another purpose of this invention are salts of mineral nutrients stabilized with amino acids and/or ammonium salt, where the amino acid is selected from the group which includes aminouksusnoy acid (glycine) and/or lysine, and the ammonium salt is either organic or inorganic.

Moreover, the next objective of this invention is a dietary Supplement containing mineral salts stabilized with amino acids and/or ammonium salt, which can improve the nutrition and health of people and animals by effectively increasing the absorption, distribution and use of minerals.

In addition, another purpose of this invention are salts of mineral nutrients stabilized with amino acids and/or ammonium salts, for which a suitable environment is, such as water, carbonated water, syrup, natural fruit juices or synthetic juices, liquid or in the form of powder, yogurt and dessert dairy products, butter, cheese and margarine.

In addition, a further aim of this invention are salts of mineral nutrients stabilized with amino acids and/or ammonium salt, desreta or selected form include pills, powder dry fizzy drink, powder, pill, candy, hard or soft gelatin capsules for submission to the pharmaceutical product, dietary Supplement or veterinary use.

Moreover, another purpose of this invention are salts of mineral nutrients stabilized with amino acids and/or ammonium salt, which may be part of starchy foods such as bread, pasta, crackers, pastries, dehydrated and concentrated foods such as stew, soups, desserts, jelly, plate cereal products in granules or extruded, cereal bars, whole grain soy or by-products in the form of flour, powder or lamellar, and oats.

In addition, a further aim of this invention are salts of mineral nutrients stabilized with amino acids and/or ammonium salts, because when the medium used is water, formed by the solution can be applied as leaf manure or other fertilizers.

Thus, another purpose of this invention is the method of synthesis of mineral salts stabilized with amino acids and/or ammonium salt, which differs in that it includes the following stages, which are:

a) pre-formed salt is dissolved in aqueous solution is of minislot and/or ammonium salt;

b) enough heat and regulate pH;

c) receive the product formed in an aqueous solution; moreover, the product can be obtained as a dry powder by evaporation of the water; you can apply a solution or dry powder.

Thus, another purpose of this invention is the method of synthesis of salts of copper, iron or manganese, stabilized with amino acids and/or ammonium salt, which differs in that it includes the following stages, which are:

a) replace the formed salts of calcium ions ferric or ferrous iron, copper or manganese by including sulphate ferric or ferrous iron, copper or manganese, respectively;

b) precipitate formed calcium sulfate, saving salt of ferric or ferrous iron, copper or manganese same anion in solution, and is associated with amino acid and/or ammonium salt;

c) filtered to separate the precipitated calcium sulfate, and the resulting product is left in the aqueous solution;

d) water is evaporated before receiving the product in the form of a dry powder.

Thus, another purpose of this invention is the method of synthesis of salts, which differs in that it includes the following stages, which are:

a) dissolved in an aqueous solution of the amino acid and/or ammonium of SOLV the prescribed ratio to the basic formula;

b) the solution is heated and adjust pH;

c) the product obtained leave in aqueous solution, and can be obtained in the form of dry powder by evaporation of water,

where salt is copper sulfate, zinc sulfate, potassium sulfate, sodium sulfate, manganese sulfate, ferric sulfate and ferrous iron, sodium chloride, potassium chloride or calcium chloride.

A brief description of graphic materials

Figure 1 shows a sample of fumarata zinc associated with glycine (Biohumoral Zn), and the standard of glycine.

Figure 2 shows a sample of fumarata zinc associated with glycine (Biohumoral Zn), and the standard of glycine after reaction with ninhydrin.

A detailed description of the invention

Were developed products of organic anions, such as fumarate, malikat, gluconate, lactate and inorganic anions, such as sulfates or chlorides, in pure form or in combinations of cations, such as calcium, magnesium, iron, zinc, copper, manganese, sodium, potassium, cobalt and Nickel, which are associated with amino acids such as glycine (aminouksusnoy acid) and/or L-lysine, and/or ammonium salt.

The formed salts are considerably higher solubility in water with acceptable taste compared to unassociated with salt, which was taken as standard, and with the same concentration of metal ion that is necessary is about to receive.

These properties of the formed products make them suitable for easy enrichment and improvement of mineral macro - and

micronutrients dietary supplements, medical products, food and beverages.

General chemical structure of the formed compounds correspond to the following scheme:

{[Ac]n·Men+← n [Amino acid and/or ammonium salt]}·xH2O,

where:

n takes values from 1 to 3, and

x takes values from 0 to 10.

Metal IUn+may be calcium, magnesium, zinc, iron, copper, manganese, sodium, potassium, cobalt, or Nickel.

The acid may be fumaric acid, lactic acid, gluconic acid, malic acid, hydrochloric acid or sulphuric acid, pure or associated.

The amino acid may be aminouksusnoy acid (glycine) and/or lysine. Ammonium salts may be organic or inorganic.

The study of the structure of the formed product showed the formation of product in which the amine nitrogen of the amino and/or ammonium salt is associated with metal coordination semipolar communication (see figure 1 and 2).

Functional identification of the coordination semipolar connection with the amine nitrogen of amino acids differed by reaction with ninhydrin (see figure 1 and 2).

Figure 1 shows a sample of fumarata zinc, associated with glycine is m (Biohumoral Zn), and the standard of glycine.

Figure 2 shows the same sample after reaction with ninhydrin. Purple color standard glycine shows that glycine is free. The yellow color corresponds to the reaction product recovered by ninhydrin, this reaction shows that the carboxyl group of glycine is free, while the amine group is associated with a metal (in this case Zn). If glycine is free, the color should be purple. However, if both a functional group of glycine (amino and carboxyl) are connected with metal (as is the case aminoheptane connections), there will be no reaction with ninhydrin, and it will be colorless.

The product is characterized as not forming the chelate, and the resulting Sol has the best properties of solubility and taste than salt.

Thus, the purpose of this invention to provide products of mineral salts of organic or inorganic acids associated with amino acid and/or ammonium salts which have the General structure:

{[AC]n·Men+← n[Amino acid and/or ammonium salt]}·xH2O,

which have better taste and greater solubility in water, which makes them more bio-available.

This may be the formation of:

a) Pre-formed salt is dissolved in an aqueous amine solution is acid and/or ammonium salt, heat and regulate the pH in a suitable way. Receive the formed product in aqueous solution. The product can be obtained as a dry powder by evaporation of water. You can apply a solution or dry powder.

b) Formed calcium salts can replace ions of divalent iron and trivalent iron, copper or manganese by adding ferric sulfate or ferrous iron, copper or manganese, respectively. Precipitate formed calcium sulfate, saving salt of ferric or ferrous iron, copper or manganese same anion in solution, and is associated with amino acid and/or ammonium salt. Filtered to separate the precipitated calcium sulfate, and the resulting product is left in the aqueous solution, which can be obtained in the form of dry powder by evaporation of the water.

c) Salts such as copper sulfate, zinc sulfate, potassium sulfate, sodium sulfate, manganese sulfate, ferric sulfate or ferrous sulfate iron also can be formed by dissolving them in aqueous solution of amino acids in the prescribed ratio to the basic formula by heating the solution and regulating the pH. The resulting product is left in the aqueous solution, and can be obtained in the form of dry powder by evaporation of the water.

(d) Salts such as copper chloride, is lurid zinc, potassium chloride, sodium chloride, manganese chloride, ferric chloride or chloride ferrous iron can also be formed by dissolving them in aqueous solution of amino acids in the prescribed ratio to the basic formula by heating the solution and adjusting the pH. The formed product is left in the aqueous solution, and can be obtained in the form of dry powder by evaporation of the water.

Comparative data solubility

1. Fumarate ferrous iron (Link 4094 Index Measurement XII ed., page 686) SP (softening point) 169,90, the content of Fe++32,87%, AW (actual weight) Fe 55,847.

Solubility in water at 25°C is 1.4 grams per liter of water. This allows 0,460 g Fe++(ferrous iron) per liter of water. Fumarate ferrous iron, stable 2 moles of glycine (aminouksusnoy acid), contains

fumarate ferrous iron 169,90 g (53,09%);

glycine (2×75,07) 150,14 g (46,91%);

product 320,04 g (17,45% Fe).

Solubility in water at 25°C for fumarata ferrous iron, stable 2 moles of glycine is 54.6 grams per liter;

for fumarata ferrous iron (53,9%) 29,0 grams/liter. This allows at 9.53 grams of Fe++(ferrous iron) per liter of water. Increasing per liter solubility: 20,7 time (the result is: at 9.53 g Fe /0,460 g Fe).

The data clearly show the increase in the water solubility of the salt, such as fumarate, ferrous iron, which is used as a source of mineral micropitting iron, dietary Supplement enriched in the food.

2. Fumarate calcium 3H2O (citing supplier Bartek Inc., Canada) SP 208,18; calcium 19,25% (AW (actual weight) Sa 40,08). Solubility in water at 25°C is 1.22 grams per litre, which allows you to dissolve 0,234 grams of CA++per liter of water. Fumarate calcium 3H2About stable 2 moles of glycine (aminouksusnoy acid). Fumarate calcium 3H2About: 208,18 58,09% 2 Glycine: 2×75,07150,1441,91% 358,32 11,18% as calcium. Solubility in water fumarata calcium, stable 2 moles of glycine, is to 50.0 grams per liter; fumarata calcium is 29,045 grams/liter; as calcium (19,25%) is 5,591 g of calcium per liter. The increase solubility: 23,9 times (resulting from: 5,591/0,234 g) as calcium.

Examples of implementation

The following specific examples which are provided herein, are used to illustrate the nature of this invention. These examples are intended for illustrative purposes only and should not be interpreted as limiting factors for the claimed invention.

Example 1

Getting calcium salts as fumarata calcium solution aminouksusnoy acid (glycine) approximately 5.0 percent.

1. A beaker 2000 SS have to fill on isenau water: 1800 Weight of calcium hydroxide (minimum 95%): to 24.84 g (checked for purity and the amount of moisture). Homogeneous distributed.

2. Weigh aminouksusnoy acid (minimum of 98.5%): 47,92 grams and add it. Heated with stirring in a water bath.

3. Weigh fumaric acid (minimum 99,0%): 37,05 grams and add it. Continue to heat it while stirring in a water bath to maintain the solution at a temperature from 60°C to 85°C for no longer than 30 minutes.

4. Take a sample and adjust pH to 6.5 with 5% p/w (of 6.2 to 6.8), using calcium hydroxide or fumaric acid, when necessary.

5. Once adjusted pH, determine the calcium, and the result should be not less than 0.56 g% calcium.

6. The resulting solution was filtered through paper, and preferably with a product that helps filtering, thus, get a clear solution.

7. The resulting solution can be dried with hot air until it is dry. The powder may contain not more than 15% water of crystallization.

8. Received from approximately 100 to 112 grams of product, depending on water of crystallization.

9. On an industrial scale solution is prepared in a suitable reactor and dried his spray system.

Example 2

Obtaining salts of bivalent iron as fumarata ferrous iron with a 10% solution of aminouksusnoy acid (g is Itin):

1. A beaker 2000 SS fill: purified water: 900 ml, or Weigh calcium hydroxide (minimum 95%): to 24.84 g (checked for purity and the amount of moisture). Homogeneous distributed by stirring.

2. Weigh aminouksusnoy acid (minimum of 98.5%): 47,92 grams and add it. Heated with stirring in a water bath.

3. Weigh fumaric acid (minimum 99,0%) 37,05 grams and added it. Continue to heat with stirring in a water bath to keep the solution at a temperature of 60°C and 85°C for no longer than 30 minutes.

4. Take a sample and adjust the pH of the solution to 4,55% p/w.

5. Once adjusted the pH, add sulfate ferrous iron 7H2About (at least 19.8% of Fe++): 88,74, the Heating stop, continuing to mix at least 30 minutes.

6. The solution was left to precipitate, and then the supernatant is filtered by the filtering method and get a clear dark green solution. The solution contains about 1.75% iron and 10% (9.5-10.5 per cent) of the product in solution.

7. The resulting solution can be dried with hot air until it is dry. The loss during the drying process at 105-108°C should be not more than 10%.

8. Receive from about 100 to 115 grams of product, depending on water of crystallization.

9. On an industrial scale solution is prepared in a suitable reactor and dried his spray system.

1. Salt mine is real nutrients, stabilized with amino acids and/or ammonium salt, where the salt obtained with the anions of organic acids and inorganic anions and cations of metal associated with amino acids and/or ammonium salt, wherein the metal cations are connected with the anions of ionic bond and covalent semipolar communication with the amino group of amino acids and/or ammonium salt, which have the following General formula
{[Ac]n·Men+←n [amino acid and/or ammonium salt]}·xH2O, where
n takes values from 1 to 3, and
x takes values from 0 to 10.

2. Salts of mineral nutrients stabilized with amino acids and/or ammonium salt according to claim 1 which are characterized in that the metal "IUn+" selected from the group which consists of the following cations:
calcium, magnesium, zinc, iron, copper, manganese, sodium, potassium, Nickel or cobalt.

3. Salts of mineral nutrients stabilized with amino acids and/or ammonium salt according to claim 1, wherein the acid is selected from the group which includes the following: fumaric acid, malic acid, hydrochloric acid or sulfuric acid, pure or associated.

4. Salts of mineral nutrients stabilized with amino acids and/or ammonium salt according to claim 1, characterized in that an amino acid selected from the group which includes the next: aminouksusnoy acid and/or lysine and ammonium salts, that is organic or inorganic.

5. Salts of mineral nutrients stabilized according to claim 1, characterized in that they are covered or enclosure (.

6. Product for the treatment of diseases caused by lack of nutrition in humans, animals and vegetable crops and source of macro and trace mineral nutrients, characterized in that it includes salt according to any one of the preceding claims.

7. A dietary Supplement to improve nutrition and health in humans and animals by effectively increasing the absorption, distribution and use of minerals, characterized in that it includes mineral salts stabilized with amino acids and/or ammonium salt according to any one of the preceding paragraphs, and at least acceptable environment.

8. A dietary Supplement to improve nutrition and health in humans and animals by effectively increasing the absorption, distribution and use of minerals according to claim 7, wherein the specified environment selected from the group which includes water, carbonated water, syrup, natural fruit juices or synthetic juices, liquid or in the form of powder, yogurt and dessert dairy products, butter, cheese and margarine.

9. A dietary Supplement to improve nutrition and health in humans and animals by effectively increasing the absorption, distribution and the applications of minerals according to claim 7, wherein the environment is selected from the group which includes pills, tablets, powder dry fizzy drink, powder, pill, candy, hard or soft gelatin capsules for submission to the pharmaceutical product, dietary Supplement or veterinary use.

10. A dietary Supplement to improve nutrition and health in humans and animals by effectively increasing the absorption, distribution and application according to claim 7, characterized in that it is part of starchy foods such as bread, pasta, crackers, pastries, dehydrated or concentrated foods such as stew, soups, desserts, jelly, plate cereal products, beans or extruded, cereal bars, whole grain soy or by-products in the form of flour, powder or lamellar, and oats.

11. The product, which is used as a foliar fertilizer or other fertilizers, characterized in that it includes a salt according to claim 1 and the aquatic environment.

12. The method of synthesis of mineral salts stabilized with amino acids and/or ammonium salt according to claim 1, characterized in that it includes a stage on which:
a) in an aqueous solution of amino acids and/or ammonium salt dissolving the pre-formed salt in a prescribed ratio to the basic formula according to claim 1,
b) is heated at a temperature of from X to Y°C and adjust the comfort of the pH to values from a to B, and
c) receive the formed product in aqueous solution.

13. The method according to item 12, characterized in that the water in the specified product in the aqueous solution is evaporated to obtain the product in the form of a dry powder.

14. The method according to item 12, wherein the salt is chosen from the group of copper sulfate, zinc sulfate, potassium sulfate, sodium sulfate, manganese sulfate and sulfate ferrous iron or ferric iron.

15. The method according to item 12, wherein the salt is chosen from the group which consists of sodium chloride, potassium chloride and calcium chloride.

16. The method of synthesis of salts of copper, iron and manganese, stable amino acids according to claim 1, characterized in that it includes a stage on which:
a) replace the calcium salts formed ions ferric or ferrous iron, copper ions or manganese, the addition of ferric sulfate or ferrous iron, sulphate of copper, or manganese, respectively,
b) precipitate formed calcium sulfate, thereby leaving salt ferric or ferrous iron, copper or manganese same anion in solution, and is associated with amino acid and/or ammonium salt,
c) filtered to separate the precipitated calcium sulphate so formed product remains in the aqueous solution,
d) water is evaporated to obtain the product with the steamboat powder.



 

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SUBSTANCE: invention relates to organometallic chemistry, in particular to novel complexes of group 8 transition metals, which are used as polymerisation catalysts of cyclic olefins, particularly dicyclopentadiene (DCPD). The catalyst is a ruthenium complex compound of general formula (1), having ligands in form of 1,3-dimesitylimidazolidinylidene, two chlorine atoms and substituted benzylidene. The substitute in the benzylidene ligand is an amino-substituted methyl group, where the amine is a di(hydroxyalkyl)amino group, as well as piperidine. The amine-containing substitute also coordinates to the ruthenium atom and forms a six-member chelate ring where X=N (Alk-OH)2, (CH2)5N , where Alk is a straight saturated hydrocarbon chain containing 2 carbon atoms. The method of preparing the catalyst involves successive reaction in a single reactor of 1,3-dimesityl-4,5-dihydro-imidazolium chloride with potassium tert-butoxide, first generation Grubb's catalyst (GrI) and then amino-containing styrene.

EFFECT: simple technology of obtaining an efficient catalyst for metathesis polymerisation of dicyclopentadiene.

2 cl, 2 ex

FIELD: medicine.

SUBSTANCE: invention refers to nanocrystalline compounds of formula (I) AOx-(L-Men+)i where AOx represents metal oxide where A it specified from Ti or Zr, x=2; Men+ represents metal ion exhibiting antibacterial activity, specified from Ag+ and Cu++, where n=1 or 2; L represents a bifunctional molecule, or a organic or metal-organic molecule able to get bound with metal oxide and ion metal Men+ simultaneously; where the organic molecule is specified from pyridine, dipyridyl, tripyridyl, functionalized with carboxylic groups (-COOH), boronic groups (-B(OH)2), or phosphonic groups (-PO3H2), or 4-mercaptophenylboronic acids; where the metal-organic molecule represents a metal-organic complex containing organic ligand coordinated with central metal atom and containing boronic (-B(OH)2), phosphonic (-PO3H2) or carboxylic (-COOH) functional group, and the groups are coordinated with central metal atom and able to get bound with metal ions with antibacterial activity; where specified organic ligand coordinated with central metal atom is specified from pyridine, dipyridyl, tripyridyl functionalized with carboxylic groups (-COOH), boronic groups (-B(OH)2), or phosphonic groups (-PO3H2), or 4-mercaptophenylboronic acids; i represents a number of groups L-Men+ bound with nanoparticle AOx. Also, there are offered a composition exhibiting antibacterial and/or antiviral activity, dermatological compositions, application of nanocrystalline compounds, a method of nanocrystalline compounds regeneration.

EFFECT: nanocrystalline compounds show effective antibacterial action.

27 cl, 4 tbl, 4 dwg

FIELD: chemistry.

SUBSTANCE: invention relates to tetra-(5-acetylamino-7-heptyloxy)anthraquinonoporphyrazines of copper and cobalt of formula .

EFFECT: obtained compounds can be used as dyes and catalysts.

4 ex, 5 dwg,

FIELD: chemistry.

SUBSTANCE: invention relates to tetra-(5-acetylamino-7-hydroxy)anthraquinonoporphyrazines of copper and cobalt of formula

.

EFFECT: compounds can be used as dyes and catalysts.

4 ex, 6 dwg

FIELD: process engineering.

SUBSTANCE: invention relates to compound that represents a multimetal complex comprising assemblage of metal complexes wherein ligand is coordinated by one metal atom or assemblage of atoms of one metal. Note here that assemblage of metal complexes are bound together by polydentant ligand which substitutes partially the ligands of metal complex assemblage and contains 2 to 1000 ligand atoms wherein each metal complex has carboxylic ligand and aforesaid polydentant ligand that represents dicarboxylic acid ligand, while metal is selected from the group consisting of Pt, Ni or Pd. Invention covers also the method of producing clusters of metal or metal oxide, the method of producing compound containing multimetal complex, and metal complex.

EFFECT: invention allows producing larger amount of controlled-size clusters.

25 cl, 3 ex, 8 dwg

FIELD: chemistry.

SUBSTANCE: invention relates to an iridium-platinum complex of formula (I) , where Cp* is selected from a group consisting of a cyclopentadienyl ligand, pentamethylcyclopentapentadienyl ligand, pentaethylcyclopentadienyl ligand and pentapropylcyclopentadienyl ligand, X is a hydrogen atom or a substitute group selected from a group consisting of a fluorine atom, a chlorine atom, a bromine atom, an iodine atom, a hydroxyl group and an organic group located in the ortho, meta or para position relative the phenyl group or a combination of these positions, and Y is selected from a group consisting of a methyl group, an ethyl group and a propyl group, wherein said organic group is selected from a group consisting of an alkyl group, alkoxy group, alkenyl group, alkenyloxy group, alkynyl group, alkynyloxy group, aryl group, aryloxy group, aralkyl group and an aralkyloxy group, which can have a heteroatom or an ether bond, which are substituted or unsubstituted and which are C1-C30 The invention also discloses a method for synthesis of the iridium-platinum complex.

EFFECT: invention enables preparation of an iridium-platinum complex capable of giving iridium-platinum clusters, having a controlled cluster size and controlled alloy composition

3 ex, 1 dwg, 10 cl

FIELD: chemistry.

SUBSTANCE: invention relates to an organonickel sigma-complex of formula ([NiBr(Xy)(bpy)], where Xy=2,6-dimethylphenyl, bry=2,2'-bipyridyl). Said complex exhibits high catalytic activity during oligomerisation of ethylene with retention of good solubility in carbon solvents.

EFFECT: possibility of oligomerisation in completely homogeneous conditions.

2 cl, 7 ex, 1 tbl, 1 dwg

FIELD: agriculture.

SUBSTANCE: invention relates to a novel compound - dihydrate of iron (II) hydroascorbate riboflavinate

(II) Fe(C6H7O6)(C17H19O6N4)2H2O which is used as an additive.

EFFECT: improved development and growth of chickens.

1 cl, 1 ex, 1 tbl

FIELD: chemistry.

SUBSTANCE: invention relates to 1-alkenylimidazole derivatives of general formula 1 , where R is vinyl, allenyl or isopropenyl, R1 is hydrogen or methyl, E is Zn (II) or Fe(III), An is chlorine or acetate, n equals 1, 2 or 4, except compounds where R is vinyl, R1 is hydrogen, E is Zn(II), An is chlorine or acetate and n equals 2.

EFFECT: compounds have antihypoxic properties for different types of hypoxia.

5 ex, 8 tbl

FIELD: chemistry.

SUBSTANCE: invention relates to tetra[4,5]([6,7]1-acetyl-2H-naphtho[2,3-D][1,2,3]triazole-5,8-dione)phthalocyanines of copper and cobalt of formula , where M denotes Cu and Co.

EFFECT: invention enables to obtain novel derivatives of phthalocyanines which can be used as dyes, as well as catalysts for various processes.

2 ex, 6 dwg

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