Method for normalising psychophysiological state

FIELD: medicine.

SUBSTANCE: duration, amplitude and form of each continuous brain signal wave are matched with parameters of each sensory signal. Recording each continuous brain signal wave, forming a matched sensory signal and exposing a patient to this signal are consistent and immediate. During the procedure, the patient is suggested to pay attention that the sensory signals perceived reflect brain work.

EFFECT: method enables more efficient process normalising psychophysiological state following stress load, psychoemotional and mental strain, and while treating functional disorders of central nervous system, psychosomatic diseases and consequences of organic cerebral affections.

4 cl

 

The invention relates to medicine, namely to non-drug ways to normalize the physiological status of the patient, and can be used to normalize the physiological status after stress, emotional and intellectual strain, as well as for the treatment of functional disorders of the Central nervous system, psychosomatic diseases and effects of organic brain damage.

It is known that currently there is increasing interest in non-pharmacological methods of rehabilitation of patients with various pathologies. One of the most rapidly developing areas of non-pharmacological correction of psycho-physiological state of the organism are neural therapy. Neural therapy use different ways of influencing the body acoustic, visual, tactile, including temperature signals. In terms of methods, neural therapy effects on the patient's sensory signals of different types operate in two modes : direct stimulation and biofeedback (BFB).

There is a method of treatment of neuroses method electroencephalographic (EEG) biofeedback (Bekshaev S., Levin, M., Yakovlev, N.M., Vaschilo Mrs x "Dynamics of patterns of EEG in patients with neurosis in the process of treatment method bio is logicheskoi feedback. Biofeedback-3. Novosibirsk, Nauka, 1998, s-211). In this method organizes feedback on the alpha rhythm of the EEG. As a sensory feedback signal using well-known melody, which is activated if the amplitude of the current oscillations of the alpha rhythm of the EEG exceeds the specified threshold, and turns off when not reaching it. The patient is placed in a comfortable chair with your eyes closed at rest. The patient is instructed to relax and to find a condition in which the melody sounds continuously. EEG recorded in bipolar lead the forehead, the nape of the neck.

As a result of such medical procedures, there is a positive dynamics of the patient.

However, this method has significant drawbacks, considerably weakening the effectiveness of therapeutic treatments. First, this method does not set the line parameters of EEG parameters of the touch signal. The melody appears only if the amplitude of EEG belonging to the alpha-rhythm, exceeds a certain threshold. Thus, in the sensor signal reflects only the time of occurrence of a limited number of EEG. Secondly, the touch signal timing EEG reflect not just that it is not possible to talk about the timing of registration of EEG of a patient with a start time in which the effects on him relevant sensory signals. The distortion of the temporal parameters of the EEG due to the fact that the duration of the tunes should be greater than 100 MS, as with less time playing the melody will not be perceived by the patient. But if the time the phone ring exceeds 100 MS (the average duration of the fluctuations of the alpha rhythm), the time of occurrence of the next fluctuations will not be reflected in the touch signal. Thus, in this way in the touch signal is almost not reflected the basic parameters of the EEG. Thirdly, the requirement for the patient to search for and hold such a functional state, which would correspond to the intensity fluctuations of the EEG is not below a predetermined threshold, limits the scope of application of the known method a cohort of patients with intact mental and volitional spheres of the psyche.

Also there is a method of neural therapy of functional disorders using dual feedback from the EEG of the patient (Fedotchev A.I., Bondar, A. T., Semenov V.S. "Neurotherapy functional disorders using dual feedback from EEG oscillators patient". All-Russian scientific-practical conference "Quantitative EEG and neurotherapy", Saint-Petersburg, 2007, p.148). In this way the parameters of the sound and light signals agree with the activity of theta and alpha EEG rhythms. When this is identified in real-time is dominated by the s usacytotece ranges of the EEG in theta and alpha rhythms, audible feedback signals with an intensity corresponding to the suppression of theta rhythm in the EEG, and simultaneously serves light rhythmic signals, tuned to the frequency of the dominant alpha rhythm of the EEG. From the patient require to find a condition in which the intensity of the sound signals would be minimal.

In this way establish compliance with the amplitude of the EEG theta and alpha rhythms with the intensity of the sensory signals of the acoustic and visual modalities. Thus, compared with the previous method increases the information content of the feedback channel. The majority of patients after these procedures, note the reduction in tension and stress.

The disadvantage of this method is, firstly, a significant limitation of the number of displayed parameters of the EEG in the touch signal. The intensity of the sensory signals are coordinated in accordance only with the amplitude of EEG theta and alpha rhythms, it does not take into account such parameters of the EEG, as the duration and shape. Secondly, do not provide the agreed time of registration of EEG of a patient with a start time of exposure to the relevant sensory signals. Thus, this method is limited to the information content of the feedback channel, resulting in reduced efficiency. Thirdly, is the patient given cognitive task, requiring from him a considerable willpower, which limits the application of this method a cohort of patients with intact mental and volitional spheres of the psyche.

A common shortcoming of these methods is, firstly, the lack of reflection in the parameters of the sensory signals of the entire set of parameters of the EEG. In the best case, the line sensor signals sets with peak indicators selected frequency bands of the EEG, whereas the duration and shape of the EEG in the parameters of the sensory signals is not considered. Second, in the proposed methods, there is no agreed time of registration of EEG of a patient with a start time of exposure to the relevant sensory signals. Therefore, these methods either ignore or significantly distort the timing of brain activity, focusing only on the amplitude-frequency characteristics. However, we know that time is one of the main coordinates of the brain, which is reflected in specific psychophysiological state temporal distribution of events in the Central nervous system (Livanov M.N. "Spatial-temporal organization of the potentials and the systemic activity of the brain". M., Nauka, 1989). Thirdly, the disadvantage of the listed method is in is the limitation of the treatment process outside of voluntary self-regulation, which in practice requires patients significant volitional efforts on the search for such psychophysiological States, electroencephalographic expression which would be consistent with a given physician-operator: melody should sound longer, the sound should be louder, etc. At the same time, it is known that the control parameters of the EEG is the easier it is, the closer to the norm indicators bioelectrical activity of the brain (Soroko S.I., Suvorov NB, kutuev V.B. have been, Bekshaev S. "Individual characteristics of arbitrary regulation of the bioelectric activity of the brain. Human physiology, 1975, No. 5, s-751). Therefore, methods of neural therapy, based on voluntary self-regulation, are not effective in the treatment of patients with impaired bioelectrical activity of the brain. In addition, the condition of voluntary self-regulation is not possible to cover the touch signal the entire range of parameters of the EEG, as multipurpose and multivariable feedback is required from the patient such efforts concentration, which cannot be implemented in terms of a disordered psychophysiological state. Thus, neural therapy, using the principle of cognitive and arbitrary control parameters of the EEG, are forced to limit the number of displayed indicators bioelectric act is vnesti brain, than weaken the information capacity of the feedback channel, and hence the efficiency of the method.

These drawbacks reduce the effectiveness of the known methods, neural therapy.

The closest to the invention, the technical essence and the achieved result is way bioacoustic correction of psycho-physiological state of the organism (Konstantinov C.V., Miroshnikov B., Sizov V. the Patent for invention №2192777 “Method bioacoustic correction of psycho-physiological state of the organism”), including the registration of EEG from two or more points lead EEG, establishing one correspondence between the spatial location of the points of registration of EEG and sources of sound, transposing each stroke, EEG separately and sequentially in the audio frequency range, the simultaneous influence of the received sound signals of the patient.

This method is chosen for the prototype of the present invention allows for comparison with other known methods to improve the accuracy of transmission of information about the current state of the Central nervous system in the feedback loop due to the transposition of the sequence of the original EEG in the area of audible frequencies and reflect the spatial parameters of EEG in a sound way. This method does not set the no threshold values for parameters of EEG and do not focus on finding and keeping the patient any state, that allows you to implement the principle of spontaneous self-regulation, allowing to expand the range of patients with various disorders of the Central nervous system.

The disadvantage of the prototype is, first, that there is no agreed time of registration of EEG of a patient with a start time of exposure to the relevant sensory signals. Secondly, the fact that the transposition of the EEG signal in the audible range of sound frequencies is not the best way of matching parameters EEG and sensory signal. If you transpose the EEG signal in the region of audible frequencies move harmonics of the original signal on the frequency scale, only with preserving original ratio of amplitudes, frequencies and phases of the EEG signal in the acoustic sensor signal. This, of course, is an important condition for the organization of biofeedback, as it allows to transmit the source information in the feedback channel with acceptable first approximation distortion. However, an important condition for the transmission of information in the channel barefoot are the characteristics of perception by the patient of the sensory signals. In this regard, the linear relationship of the amplitudes, frequencies and phases of the original signal, which is used in the transposition signals, does not provide high efficiency of this method. Thirdly, that in this way create Senso the data signals only acoustic modality, that limits the scope of application of the method a cohort of patients with intact hearing. Fourthly, that the way of transposition frequencies unacceptable when creating the sensory signals of the visual and tactile modalities. Fifthly, that this method does not offer the patient to pay attention to what he perceived sensory signals reflect the workings of his brain, which negatively affects the efficiency of the process of normalization of the physiological status of the patient.

These drawbacks selected for the prototype method limit its effectiveness.

The aim of the proposed invention is to improve the efficiency of processes to normalize the physiological status of the patient after stress, emotional and intellectual tension, and in the treatment of functional disorders of the Central nervous system, psychosomatic diseases and effects of organic brain damage.

This goal is achieved by the fact that in the proposed method, the normalization of the psychophysiological state separately and sequentially register each oscillation signal of a brain of the patient, forms a corresponding touch signal in accordance with the duration, amplitude and shape of each of the oscillation signal of the brain and affect patients the NTA that the touch signal. The registration of each of the oscillation signal of the brain, the formation of the corresponding touch signal and the impact on patient this signal is carried out consistently, without time intervals between them. The patient is offered during the procedure to pay attention to what he perceived sensory signals reflect the workings of his brain.

Thus, the brain signals present as a temporal sequence of oscillations. The main parameters of the oscillations (duration, amplitude and shape) will agree with the parameters of the sensory signals, and each unique oscillation signal of the brain has a unique touch signal. In this way the touch signal with high accuracy reflect the basic parameters of the oscillation signals of the brain. The method allows to increase the efficiency of the processes of normalization psychophysiological state after stress, emotional and intellectual tension, and in the treatment of functional disorders of the Central nervous system, psychosomatic diseases and effects of organic brain damage.

Comparative analysis of the prototype and the proposed method shows that the differences of the latter lie in the way of receiving the touch signals and the method of exposure of the touch signal and the patient, and, therefore, the proposed method meets the criterion of "novelty."

Comparison of proposed method with other known in the field of technical solutions allows us to conclude that it stems from them not obvious and, therefore, meets the criterion of "inventive step".

Compliance with the proposed method the criterion of "industrial applicability" is confirmed by the implementation in devices, medical equipment.

The inventive method is implemented by using a device that contains the block registration of brain signals (block 1), the sensor signals of the brain, the transformation block brain signals to corresponding sensory signals (block 2), the unit impact on the patient generated sensory signals (block 3), and the control unit for the current parameters of the oscillations of brain signals (block 4) and the control unit (unit 5).

During the treatments fluctuations of brain signals recorded by the unit 1, unit 4 according to the fluctuations of brain signals control the current psychophysiological state of the patient. In unit 2 recorded by sensors fluctuations of brain signals is converted into sensory signals taking into account the duration, amplitude and shape of each of the oscillation signals of the brain and with the help of block 3 formed the sensory signals affect patient is A. The registration of each signal of the brain, the formation of the corresponding touch signal and the impact on patient this signal is carried out sequentially without gaps between them. The patient is offered during the procedure to pay attention to what he perceived sensory signals reflect the workings of his brain. The duration of treatment procedures set unit 5.

At the Institute of Experimental Medicine (Saint-Petersburg) in the Physiological Department of them. Pavlov received the research results of applying the proposed method in the treatment of patients with functional disorders of the Central nervous system, psychosomatic diseases and the effects of organic brain damage of varying severity. In the course of the research with each patient was conducted from 5 to 7 treatments. During procedures, we recorded brain signals of the patient and affected the patient's sensory signals generated in accordance with the duration, amplitude and shape of each of the oscillation signal of the brain. The average duration of each procedure was 15-20 minutes.

In the course of the treatments showed normalization of the physiological status of patients, which was reflected in significantly reducing the level of reactive and personal anxiety on test Selber the EPA Hanina, improving health, activity and mood test SAN (health, activity, mood, reducing depression test Ted (anxiety and depression), reduce errors and decrease the reaction time in the visual and acoustic sensory samples, the increase in the index of the alpha rhythm, the reduction of the index of beta-rhythm and reducing inter-hemispheric asymmetry.

Thus, the proposed method is compared with the prototype helps to restore physiological state, by establishing one correspondence amplitude, duration and shape of each of the oscillation signals of the brain with the corresponding parameters of the sensory signals, which provide the impact on the patient, but also due to the fact that the registration of each of the oscillation signal of the brain, the formation of the corresponding touch signal and the impact on patient this signal is carried out sequentially without gaps between them.

The proposed method is to normalize the physiological status can be widely used in rehabilitation and health settings.

1. Way to normalize the physiological status, including registration of brain signals of the patient, converting the selected parameters of brain signals in the sensor signals and the effects on the patient of these sensory signals, characterized in that each sensor signal is formed in accordance with the duration, amplitude and shape of each of the oscillation signal of the brain, and the registration of each of the oscillation signal of the brain, the formation of the corresponding touch signal and the impact on patient this signal is carried out consistently, without time intervals between them.

2. The method according to claim 1, wherein the patient is instructed to pay attention to what he perceived sensory signals reflect the workings of his brain.

3. The method according to claim 1 or 2, characterized in that the sensory signals are used separately audible, visual or tactile stimuli.

4. The method according to claim 1 or 2, characterized in that the sensory signals use any complex combination of audible, visual and tactile impact.



 

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