Long-term nutrition for senile patients

FIELD: medicine.

SUBSTANCE: invention refers to clinical nutrition. A method of the long-term enteral nutrition of a senile patient includes the following stages: long-term enteral introduction to a senile patient at least once a day of a nutritious product containing: protein source which contains 14-20% of the calorie count; carbohydrates source which contains 10-50% of the calorie count; fat source which contains 30-45% of the calorie count; dietary fibres source which makes 10-25 g per 1 litre of the product and 8.0-18.0 mcg of chrome per 100 kcal of the product. In 100 kcal of the product the composition contains at least: 30 mg of choline, 5.0 mg of taurine and 3.0 mg of carnitine; one or more of at least: 0.1 mg of beta-carotene, 0.2 mg of lycopene and 0.05 mg of lutein. As a version, the composition described above for the long-term enteral nutrition of a senile patient contains sufficient amount of mineral substances (particularly, calcium) and vitamins (particularly, vitamin D).

EFFECT: invention allows to provide a senile patient with the effective long-term enteral nutrition which optimises a glycaemic response for glycemia control, reduces insulin resistance and/or modulates a glucose response, and also maintains the metabolic status.

30 cl, 2 ex

 

The invention relates to nutrition, more specifically to clinical nutrition.

The level of technology

As a result of many diseases, injuries and complications, patients may be unable to obtain the necessary nutrition by absorption of food through the mouth, for example eat food. So you know the supply of clinical nutrition either via feeding tube or parenteral. Many different ready-made forms were developed to supply such clinical nutrition.

Although, with regard to typical products for enteral feeding, these products are intended for short term use, usually 10-24 days. In this regard, the products usually provide vital nutrients to supply the necessary nutrition of patients with acute pathology during their stay in hospital. Although these products are suitable for such short-term use, they are not necessarily intended for long-term supply (feeding) patients. With the advances in medicine, leading to the increase of life expectancy and improvement in the treatment of diseases, many individuals can benefit from products that are designed to supply long-term enteral nutrition.

The invention

The present invention offers a means of delivering long-term enteral nutrition patients that require it. Bo is it specifically the present invention provides methods and compositions for the supply of long-term enteral nutrition for the elderly patient.

To this end, in one embodiment of the present invention proposes a method of supply probe power of the elderly patient, containing the stage: introduction during a long period, at least once a day, through the probe, nutritional product, comprising: a source of protein, which is 14-20% of the energy value of the product; a source of carbohydrates, which is 10-50% of the energy value of the product; a source of lipids that 30-45% of the energy value of the product; a source of dietary fiber, which gives 10-25 g per liter of product; and 8,0-18,0 mcg of chromium per 100 kcal of the product.

According to the method in one embodiment of the lipids can contain 40-60% by weight of monounsaturated fats (MUFA). In one embodiment, the product contains not more than 1.1 g / 100 kcal) saturated fatty acids (SFA), and the product contains 0.4 to 2.0% of the weight of the lipids in the form of eicosapentaenoic acid (EPA). The protein source can be selected from the group consisting of casein, whey and soy. The carbohydrate may be selected from the group consisting of fructose, polyalcohols, xylytol, starches, dextrins and maltodextrins.

According to the way the product may contain other components. For example on 100 kcal of the product may contain, at least: 30 mg of choline; 4.0 mg of taurine; and/or 3.0 mg of carnitine. Optionally, the product may contain per 100 kcal, at m the d: 0.1 mg beta-carotene; 0.2 mg of lycopene; and/or 0.05 mg of lutein.

In one embodiment of the method, the specific energy is 0.8-1.3 kcal/ml If desired, the product contains prebiotic and provides both soluble and insoluble fiber. At least 25% by weight of the fiber can be soluble.

In another embodiment of the present invention provides a method of feeding the elderly patient, which includes stages: introduction for a long period, at least once a day, using a probe composition comprising: a protein source; a source of fat; a source of carbohydrates, providing not more than 44% of the energy of the composition; a source of dietary fiber, containing at least 25% by weight soluble fibers; chrome, providing at least an 8.0 μg per 100 kcal of the product; vitamin D and calcium.

In one embodiment of the way vitamin D is at least 0.5 μg per 100 kcal and calcium is at least 35 mg per 100 kcal.

In one embodiment of the method, the protein source is selected from the group consisting of casein, whey and soy, and carbohydrates selected from the group consisting of fructose, polyalcohols, xylytol, starches, dextrins and maltodextrins.

Also, according to the present invention features a composition for the supply of long-term enteral feeding, comprising: a source of protein that contains 14-20% ene the energy value of the product; the source of carbohydrates, which contains 10-50% of the energy value of the product; a source of lipids, which contains 30-45% of the energy value of the product; a source of dietary fiber, which gives 10-25 g per liter of the product and contains both soluble and insoluble fiber, where at least 25% by weight of the fibers are soluble; 8,0 - 18,0 mcg of chromium per 100 kcal of the product.

A number of modifications and additions to the product are possible. For example, lipids can contain 40-60% by weight of monounsaturated fats, not more than 1.1 g per 100 kcal saturated fatty acids and 0.4 to 2.0% by weight of lipids in the form of eicosapentaenoic acid. The protein source can be selected from the group consisting of casein, whey and soy, and carbohydrates can be selected from the group consisting of fructose, polyalcohols, xylytol, starches, dextrins and maltodextrins. In one embodiment, the product contains 100 kcal, at least: 30 mg of choline; 4.0 mg of taurine and 3.0 mg of carnitine. In another embodiment, the product contains 100 kcal, at least: 0.1 mg beta-carotene; 0.2 mg of lycopene and 0.05 mg of lutein.

The advantage of the present invention is that offer superior products for enteral feeding.

Moreover, an advantage of the present invention is that offers improved ways to supply probe power.

Moreover, p is akusherstvo of the present invention is offered the song to ensure long-term enteral nutrition to elderly patients.

An additional advantage of the present invention is that the ways of the supply of long-term enteral nutrition to elderly patients.

Additional characteristics and advantages described herein will become apparent from the following detailed description of the invention.

Disclosure of inventions

The present invention relates to clinical nutrition. More specifically the present invention relates to the supply of elderly patients with long-term enteral nutrition. In this context, the term "long-term" means longer than one month (30 days). In this context, the term "probe" means the supply of the patient product through the feeding probe, which is placed inside the part of the digestive tract of the patient, such as nasogastric feeding tube or percutaneous endoscopic astronomicheskii probe. Applicants simultaneously file a patent application entitled "Methods of long-term supply power, which reveals the different formulations of long-term enteral feeding and industrial methods based on them, the disclosure of which is hereby incorporated here by reference.

Products for long-term enteral feeding preferably is designed for elderly patients. In this context, the term "elderly patients" refers to adult patients age 65 years or older, who are unable to obtain food by normal food, but which are normally metabolic (i.e. not suffer from disorders of metabolism). This patient was able to pre-transfer surgery for cancer in the head or neck, resulting in incomplete digestive tract or the inability to swallow, could get injured neck that made him or her unable to swallow, or may be unable to swallow the result of neurological damage caused by stroke, for example, or may suffer from disorders, such as Alzheimer's disease, Parkinson's disease, dysphagia, or myocardial infarction. In this context, the term "normal food" means obtaining, at least, almost all of food by food, i.e. by using the mouth, without the use of any of the feeding tube or parenteral feeding.

In the composition according to the present invention, an attempt was made to optimize glycemic response in elderly patients fed a prepared form. Recurrent episodes of hyperglycemia are the main difficulty with probe feeding the elderly. They can be particularly acute for those elderly patients who may need dolgor the current probe power for the rest of their lives. Hyperglycemia may exacerbate chronic weak inflammation, which is believed to be associated with many symptoms of aging. For example, recurrent episodes of hyperglycemia may be associated with inflammation of the endothelium of blood vessels, leading to narrowing of blood vessels. This can lead to cardiovascular disease and the problems associated with it. Similarly, it can increase the amount of urine, which leads to excessive loss of minerals and, therefore, the load on the kidneys.

Accordingly, according to the present invention, in at least one embodiment, the finished form is able to maintain metabolic status in elderly patients receiving long-term enteral nutrition by maintaining blood glucose homeostasis. Designed composition for reducing insulin resistance and/or modulate glucose response. In one embodiment designed ready form to supply the necessary power for a long period at 1500 ml / day.

Preferably, the composition provides a source of protein, covering 14-20% of the total content of calories in the product. Can be used any high-quality source of protein or a mixture that provides a balanced profile of essential amino acids. Examples include casein, whey and soy is protein. Proteins can be native (solid) or partially gidrolizovannykh. If desired, can be added free amino acids. Preferably, at least 50% of the protein mass is whey protein. In one embodiment, a mixture of 60% protein and 40% protein soybean.

Preferably the source of carbohydrates provides 10-50% of the total content of calories in the product. In the preferred embodiment it provides less than 45% of the total content of calories. Carbohydrate components chosen for the preferred low glycemic response. Suitable carbohydrates are fructose, sugar alcohols such as sorbitol and xylitol, starches, dextrins, maltodextrins, and mixtures thereof.

Preferably the source of lipids provides 30-45% of the total content of calories, and 40-60% by weight of lipids are monounsaturated fatty acids (MUFA). Any suitable mixture of dietary lipids may be used, such as saturated fatty acids (SFA), MUFA, polyunsaturated fatty acids (PUFA) and triglycerides of medium chain length (MCT). Preferably saturated fatty acids do not constitute more than 1.1 g/100 kcal. Preferably 0.4 to 2% by weight of lipids is eicosapentaenoic acid.

Additional substances can be added to the product. For example, per 100 kcal may be present choline on the Aries, at least 30 mg, taurine is present at a level of at least 5.0 mg and carnitine at the level of at least a 3.0 mg as phytonutrients, they may be present per 100 kcal as follows: beta-carotene, at least 0.1 mg, lycopene, at least 0.2 mg and lutein at least 0,05 mg In one embodiment of the energy density of the product is between 0.8 and 1.3 kcal/ml

According to the recipe of the present invention by providing a low consumption of carbohydrates and adding fructose, fiber and chromium formulation helps to maintain blood glucose homeostasis. Moreover, the formulation able to cope with the proliferation of glucose intolerance in patients.

In the embodiment of the invention applied fructose. Fructose is transferred into the cells without any intermediate insulin intervention. Therefore, it is an excellent source of energy, alternative glucose. In addition fructose catalyzes the use of glucose for effects on the liver. These two mechanisms help to avoid excessive postprandial hyperglycemia.

The use of chromium in the composition is advantageous because it enables the oxidation of glucose. It limits intolerance in relation to glucose and reduces the need for insulin.

The modified fibers regulates adsorbs is glucose. This restricts blood glucose peaks. In addition, the intake of vitamin D is high in order to maintain reserves in the bones.

As indicated above, the present invention provides methods and products that are optimized and/or improved for long-term use. In one embodiment the patient give this product outside the hospital. For example, the products can be given in a nursing home, care for the sick or even the home of the patient. Preferably the foodstuff is placed in a plastic bag. Many such packages are known, for example in this area is known packages of 500 ml, 1000 ml and 1500 ml it Should be noted, however, that any suitable container can be used to host food product. In one embodiment the product is intended to supply the necessary power at 1500 ml per day, although persons skilled in this field will appreciate that changes at this level possible.

In one embodiment foods specifically designed so that they can provide the full long-term power, and an attempt is made to provide the same macro - and micronutrients, which would swallow the person taking normal food. Thus, in one embodiment the finished form can mimic what describe here how 5/8 per day. In this context, the term "5/8" a day from OSISA to state recommendations for consumers to eat a day from five to eight servings of fruits and vegetables. Thus, in one embodiment the products are designed to try as much as possible to simulate normal power, which preferably eaten by individuals who do not need to probe the product, by providing micronutrients and phytonutrients found in fruits and vegetables. In one embodiment of the present invention provides a method of product development long-term enteral feeding, based on an attempt to imitate 5/8 per day. By providing such a food product can be maintained antioxidant status of the patient, as well as metabolic status. The goal is to put these patients in the position, as far as possible, comparable with the situation in which completely healthy individuals of the same age eat a balanced diet.

It was found that the phytonutrients provide the following properties: antioxidant, anti-inflammatory, detoxification, cancerogene, to prevent atherosclerosis, reduce metabolic syndrome and preventing osteoporosis. To obtain the necessary phytonutrients, compositions of the present invention can include one or more carotenoids, such as lycopene (tomato), beta carotene (carrots, spinach, tomato), lutein (spinach), beta cryptoxanthin, vitamins, such as mixed Tocopherols(oil and nuts) and vitamin C (orange); and polyphenols, such as catechins (green tea).

Preferred products include the necessary nutrients to supply the full power of the patient on a long term basis. For this purpose, the products include, among other possible ingredients: protein, carbohydrate, fat, vitamins and minerals. In one embodiment the products are substantially, if not completely correspond, at least in a certain state requirements. In this context, "state requirements" means any recommendations of any one of the following governments: the United States, usually USRD, Germany, usually Germ RD and France, usually French RD. In one embodiment the food product meets or exceeds at least one of the state requirements.

Examples of the present invention will be given below, but not for the purpose of limiting the scope of the present invention.

Example # 1 - the product for the elderly

4,00
The embodiment of 1500 mlThe embodiment 100 ml
Calorieskcal1500100,00
Proteinsg60
Protein wheyg362,40
Isolate soy proteing241,60
Carbohydratesg17611,70
Fructoseg161,1
Maltodextrinsg865,8
Starchg57the 3.8
Carbohydrates from other sourcesg171,1
Fiberg211,4
Insoluble%66 66
Instant%3434
Lipidsg674,5
SFA (including MCT)g201,3
MUFAg352,3
PUFAg100,68
Linoleic acid (n-6)gthe 5.70,38
α-linolenic acid (n-3)g1,10,07
The ratio of ω6/ω3g3,13,1
EPAg0,450,03
DHAg0,300,02
MCTg100,67
Mineral substances and microelements
Sodiummg118579
Potassiummg3195213
Calciummg120080
Phosphorusmg79553
Magnesiummg34523
Chloridemg1650110
Iron mg12,30,82
Zincmg151,0
Coppermg2,70,18
Fluoridemg1,20,08
Chromemcg22515
Molybdenummcg19513
Seleniummcg1006,7
Manganesemg4,00,27
Iodinemcg15010
Vitamins
Vitamin a, totalME4200 280
Vitamin Dmcg14,70,98
Vitamin EME67,54,5
Vitamin Kmcg21014,0
Vitamin Cmg1208,0
Vitamin B1 (Thiamine)mg1,50,10
Vitamin B2 (Riboflavin)mg1,950,13
Vitamin B3-PP (Niacin)mg151,00
Vitamin B5 (Pantothenic acid)mg8,00,53
Vitamin B6mg2,250,15
(Pyridoxine)
Vitamin B8 (Biotin)mcg573,80
Vitamin B9 (Folic Acid)mcg40527
Vitamin B12mcg4,80,32
More
Cholinemg79553
Carnitinemg15010
Taurinemg81of 5.4
Lycopene (tomato)mg5,90,39
Beta-carotene (carrots)mgthe 3.80,25
Lutein (Spinach mg1,430,095

Example # 2 - the product for the elderly

66
The embodiment of 1500 mlThe RANGE for 100 kcalThe embodiment 100 ml
Calorieskcal1500of 0.8-1.3 kcal/ml100,00
Proteinsg6014-20% of the total energy value. Any balanced profile, preferably >50% by weight of protein in the form of whey partially hydrolyzed or native form4,00
Protein wheyg362,40
Isolate soy proteing241,60
Carbohydratesg17611,70
Fructoseg161,1
Maltodextrinsg865,8
Starchg57the 3.8
Carbohydrates from other sourcesg171,1
Fiberg2110-25 g/l1,4
Insoluble fiber%66
Soluble fiber%34soluble, at least 25%, preferably, soluble in 30-55%34
Lipidsg6730-45% of the total energy value4,5
SFA (includes MCT)g20saturated fats (excl. MCT) <10% of total1,3
the energy value or <1,11 g/100 kcal
MUFAg3540-60% by weight of the total Koli is esta lipids 2,32
PUFAg100,68
Linoleic acid (n-6)gthe 5.70,38
α-linolenic acid (n-3)g1,10,07
The ratio of ω6/ω33,12-63,1
EPAg0,450.4 to 2% by weight of total lipids (optional)0,03
DHAg0,300,02
MCTg100,67
Mineral substances and microelements
Sodiummg118579
Potassiummg3195213
Calciummg1200>3580
Phosphorusmg79553
Magnesiummg34523
Chloridemg1650110
Ironmg1230,82
Zincmg151,0
Coppermg2,70,18
Fluoridemg1,20,08
Chromemcg2258-1815
Molybdenummcg19513
Seleniummcg100,56,7
Manganesemg4,00,27
Iodinemcg15010
Vitamins
Vitamin a, totalIU 4200280
Vitamin Dmcg14,7>0,50,98
Vitamin EME67,54,50
Vitamin Kmcg21014,0
Vitamin Cmg1208,0
Vitamin B1 (Thiamine)mg1,50,10
Vitamin B2 (Riboflavin)mg2,00,13
Vitamin B3-PP (Niacin)mg151,00
Vitamin B5 Pantothenic acid)mg 8,00,53
Vitamin B6mg2,30,15
(Pyridoxine)
Vitamin B8 (Biotin)mcg573,80
Vitamin B9 (Folic acid)mcg40527
Vitamin B12mcg4,80,32
More
Cholinemg795If present, >30 mg/100 kcal53
Carnitinemg 150If present, >3 mg/100 kcal10
Taurinemg81If present, >4 mg/100 kcalof 5.4
Lycopene (tomato)mg5,9>0.2 mg/100 kcal0,39
Beta-carotene (carrots)mgthe 3.8>0.1 mg/100 kcal0,25
Lutein (spinach)mg1,43>0.05 mg/100 kcal0,095

According to the embodiment of the present invention prepared from examples either No. 1 or 2 can be given to elderly patients who can't eat normal food at least once a day on a long term basis as long as is necessary.

It should be understood that various changes and modification data of the preferred embodiments described herein will be apparent to qualified specialists in this field. Such changes and modifications can be made, not in the walking beyond the nature and scope of the present invention and without sacrificing its intended benefits. So I expect that such changes and modifications covers the attached claims.

1. The method of supply of the elderly patient long-term enteral nutrition for glycemic control, optimization of glycemic response and maintain metabolic status, which includes stages:
introduction the elderly patient at least once a day over a long period through the probe nutritional product that contains:
source of protein that contains 14-20% of the energy value of the product;
the source of carbohydrates, which contains 10-50% of the energy value of the product;
the source of lipids, which contains 30-45% of the energy value of the product;
the source of dietary fiber, which gives 10-25 g per liter of product; and
8,0-18,0 mcg of chromium per 100 kcal of product
on 100 kcal of the product, at least: 30 mg of choline, 5.0 mg of taurine and 3.0 mg of carnitine,
on 100 kcal of the product one or more of at least: 0.1 mg beta-carotene, 0.2 mg of lycopene and 0.05 mg of lutein.

2. The method according to claim 1 that is effective in optimizing glycemic response.

3. The method according to claim 1, which is effective in maintaining metabolic status.

4. The method according to claim 1, where the lipids contain 40-60% by weight of monounsaturated fats.

5. The method according to claim 1, where at least 25% by weight of the fiber is soluble.

6. Pic is b according to claim 1, where the protein source is selected from the group consisting of casein, whey and soy.

7. The method according to claim 1, where the carbohydrate is selected from the group consisting of fructose, polyalcohols, xylytol, starches, dextrins and maltodextrins.

8. The method according to claim 1, where the product contains no more than 1.1 g per 100 kcal saturated fatty acids.

9. The method according to claim 1, where the product contains 0.4 to 2.0% of the weight of the lipids in the form of eicosapentaenoic acid.

10. The method according to claim 1, where the energy density is 0.8-1.3 kcal/ml

11. The method according to claim 1, where the source of dietary fibers provide both soluble and insoluble fiber.

12. The method according to claim 1, where the product contains a prebiotic.

13. The method of supply of the elderly patient long-term enteral nutrition for glycemic control, which includes stages:
introduction during a long period, at least once a day through the probe composition containing:
the protein source;
the source of fat;
the source of carbohydrates, providing not more than 44% of the energy of the composition;
the source of dietary fiber, containing at least 25% by weight soluble fibers;
chrome, providing at least 8,0-18,0 μg per 100 kcal of the composition, vitamin D and calcium,
on 100 kcal of the composition, of at least: 30 mg of choline, 5.0 mg of taurine and 3.0 mg of carnitine,
on 100 kcal of the composition one or more of at least: 0.1 mg beta-carotene, 0.2 mg Liko the ins and 0.05 mg of lutein.

14. The method according to item 13, which is effective in optimizing glycemic response.

15. The method according to item 13, which is effective in maintaining metabolic status.

16. The method according to item 13, where vitamin D is at least 0.5 μg per 100 kcal.

17. The method according to item 13, where the calcium is at least 35 mg per 100 kcal.

18. The method according to item 13, where the protein source is selected from the group consisting of casein, whey and soy.

19. The method according to item 13, where the carbohydrate is selected from the group consisting of fructose, polyalcohols, xylytol, starches, dextrins and maltodextrins.

20. The method according to item 13, where the product contains no more than 1.1 g per 100 kcal saturated fatty acids.

21. The method according to item 13, where the energy density is 0.8-1.3 kcal/ml

22. The composition of the product to supply long-term enteral nutrition for the elderly patient to monitor blood glucose, containing:
source of protein that contains 14-20% of the energy value of the product;
the source of carbohydrates, which contains 10-50% of the energy value of the product;
the source of lipids, which contains 30-45% of the energy value of the product;
the source of dietary fiber, which gives 10-25 g per liter of the product and contains both soluble and insoluble fiber, where at least 25% by weight of the fibers are soluble;
8,0-18,0 mcg of chromium per 100 kcal of the product;
where p is oduct contains enough minerals and vitamins, to meet government regulations.

23. Product p.22, where the lipids contain 40-60% by weight of monounsaturated fats.

24. Product p.22, where the protein source is selected from the group consisting of casein, whey and soy.

25. Product p.22, where the carbohydrate is selected from the group consisting of fructose, polyalcohols, xylytol, starches, dextrins and maltodextrins.

26. Product p.22, containing not more than 1.1 g per 100 kcal saturated fatty acids.

27. Product p.22 containing 0.4 to 2.0% by weight of lipids in the form of eicosapentaenoic acid.

28. Product p.22 containing 100 kcal, at least: 30 mg of choline, 5.0 mg of taurine and 3.0 mg of carnitine.

29. Product p.22 containing 100 kcal, at least: 0.1 mg beta-carotene, 0.2 mg of lycopene and 0.05 mg of lutein.

30. Product p.22, where energy density is 0.8-1.3 kcal/ml



 

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18 cl, 2 tbl, 2 ex

FIELD: food industry.

SUBSTANCE: invention relates to food industry and involves production of a food additive intended to be used in food mainly for enrichment with iron. The method involves interaction of ferric iron citrate with water and ammonium hydroxide at 55-60°C while mixing until iron citrate is completely dissolved. Mass ratio of the components is 1:(0.3-0.7):(0.30-0.44) respectively. Crystalline citric acid is added at a rate of 8-33% of the iron citrate weight. The stock obtained is stirred until pH is 3.5-5.0.

EFFECT: invention ensures production of iron-bearing food additive which is ferric ammonium (III) citrate green in a bioavailable form with a high yield of the product.

1 tbl, 3 ex

FIELD: food industry.

SUBSTANCE: invention relates to food industry, namely to new protein, amino acids and micro elements sources. Food chelate complex contains protein hydrolysate and micro elements connected into chelate compounds. Mussels meat fermentative hydrolysate is used as protein hydrolysate, zink is used as micro elements at 40-60 mg\g of dry preparation. Chrome can also be used as micro element at 1.5-2.5 mg/g of dry preparation content.

EFFECT: invention allows to obtain firm compounds which increase body adaptative reserves.

2 cl, 3 tbl, 5 ex

"vitapant" balsam // 2376891

FIELD: food industry.

SUBSTANCE: invention is related to the field of food industry and preventive medicine. Antlers and magnesium balsam contains alcohol-free extract made of unossified antlers, carbohydrates, magnesium sulphate, alcohol-free vegetable concentrated tonic extract and water. Alcohol-free vegetable extract is rootstocks and roots of Rhaponticum carthamoides or ginseng roots or Manchurian aralia roots. Balsam contains components in following ratio, wt %: alcohol-free antlers extract 2.0-6.0, alcohol-free vegetable tonic concentrated extract 0.5-1.5, magnesium sulphate 4.0-7.0, carbohydrates 25.0-45.0, water - the rest.

EFFECT: invention allows to obtain biologically active additive - balsam in fluid form with no alcohol containing components with increased immunomodulating activity.

6 cl, 1 tbl, 6 ex

FIELD: food industry.

SUBSTANCE: invention relates to food industry and can be used while producing biologically active supplements (BAS) for food and food products. Composition contains calcium, phosphor, magnesium sources and ascorbic acid, vitamins D3, B2, B6, extracts of John's wort, owa-tree fruits, Kurile tea, unossified antlers hematogen made of male maral blood and condimental substances. Composition components are used in certain ratio. Composition is proposed mostly for men. Composition contains calcium, phosphor, magnesium sources and ascorbic acid, vitamins D3, B2, B6, extracts of John's wort, rowa-tree fruits, Kurile tea, unossified antlers hematogen made of male maral blood and condimental substances. Composition also contains components in certain ratio and proposed for women. As a version composition contains sources of calcium, phosphor, magnesium, ascorbic acid, vitamins D3, B2, B6, rosehips extracts, black currant extracts, rowa tree fruits extracts, unossified antlers hematogen made of male maral blood and condimental substances and proposed for non-adults.

EFFECT: invention allows to obtain new balanced compositions used as preventive measures of calcic deficiency and normalisation of calcium metabolism.

15 cl, 3 ex

FIELD: food industry.

SUBSTANCE: group of inventions relates to food industry, in particular to production of food biologically active supplements (in tabletted form) containing organically bound iodine and intended for group or individual iodine hunger prophylaxis. The biologically active food supplement production method envisages mixing pectin and iodine solution prepared be way of crystal iodine dissolution in water solution of potassium iodide. Mixing pectin and iodine solution is performed by way of pectin moistening with the solution in a ratio of 1:0.8. One mixes iodine containing pectin at room temperature during an hour in a closed reactor with an anchor stirrer at 25 rpm. Calcium phosphate is added in a ratio of 1:3 to iodine containing pectin, extrusion is performed. The produced extrudate is subjected to granulation by spheronisation; formed granules are dried in a drying box with artificial ventilation at a temperature of 50°C till residual humidity is no more than 5%. Magnesium stearate is introduced in an amount of 1% to the granules weight; tabletting is performed. The biologically active food supplement contains crystal potassium iodide, pectin, calcium phosphate and magnesium stearate in a specific components proportion.

EFFECT: invention usage provides for production of a iodine containing organo-mineral complex in tabletted form with elementary iodine content in every tablet - 75 mcg, ingredients thereof promote optimisation of iodine metabolism and iodine fixation effectiveness due to enterosorption of strumogens.

2 cl

FIELD: food industry.

SUBSTANCE: group of inventions relates to food industry, in particular to production of food biologically active supplements (in tabletted form) containing organically bound iodine and intended for group or individual iodine hunger prophylaxis. The biologically active food supplement production method envisages mixing pectin and iodine solution prepared be way of crystal iodine dissolution in water solution of potassium iodide. Mixing pectin and iodine solution is performed by way of pectin moistening with the solution in a ratio of 1:0.8. One mixes iodine containing pectin at room temperature during an hour in a closed reactor with an anchor stirrer at 25 rpm. Calcium phosphate is added in a ratio of 1:3 to iodine containing pectin, extrusion is performed. The produced extrudate is subjected to granulation by spheronisation; formed granules are dried in a drying box with artificial ventilation at a temperature of 50°C till residual humidity is no more than 5%. Magnesium stearate is introduced in an amount of 1% to the granules weight; tabletting is performed. The biologically active food supplement contains crystal potassium iodide, pectin, calcium phosphate and magnesium stearate in a specific components proportion.

EFFECT: invention usage provides for production of a iodine containing organo-mineral complex in tabletted form with elementary iodine content in every tablet - 75 mcg, ingredients thereof promote optimisation of iodine metabolism and iodine fixation effectiveness due to enterosorption of strumogens.

2 cl

FIELD: medicine.

SUBSTANCE: invention relates to medicine, food and cosmetic industry. Mixture of superdispersed powder from cysts or nauplii, or adult maxillopods Artemia saline is prepared with polar extractant in the form of water or water-glycerin solution with initial content of polar extractant of at least 40 wt %. Multiple extraction is carried out, at least for 3 times, each time draining at least 4 volumes of extract and with renewal of extractant in process of mixing, extract is filtered, and its parts are combined. Residue is removed, and polar extractant is distilled from Artemia extract. Prior to preparation, to extraction of mixture of initial components, the following components are added to polar extractant - non-polar extractant in the ratio of at least 1:1 and solubiliser with hydrophilic-lipophilic balance of at least 12.0, and its content in the mixture of extractants makes not more than 7.0 wt %. Ratio of superdispersed powder from cysts or nauplii or adult maxillopod Artemia saline and prepared mixture of extractants with solubiliser makes not more than 1:5. Content of polar extractant in water or water-glycerin solution during its renewal in process of multiple extraction of raw materials is subsequently increased from 40 to 70 wt %. Prior to distillation of polar extractant is separated into hydrophilic and lipophilic fractions by means of settling for at least 5 hours and draining lipophilic fraction. Hydrophilic fraction of product is exposed to distillation of polar dissolvent.

EFFECT: invention makes it possible to reduce losses of biologically active substances in process of their extraction from raw materials.

12 cl, 14 ex, 2 tbl

FIELD: food industry.

SUBSTANCE: invention relates to food industry and can be used as dietary supplement for food intended to clean the organism. The dietary food supplement is represented by a dry mixture of milled drug raw materials. The mixture contains in wt %: stevia leaves 10-35, green tea leaves - 10-30, blackcurrant leaves - 10-30, meadow pine grass - 5-20, buckthorn bark - 10-50, fennel fruits 5-15 and natural flavours or nature-identical flavours ensuring a fruit-and-berry taste - 0.01-5.00.

EFFECT: invention allows to produce a product with dietary properties, being a powerful source of bioflavonoids, silicon, catechines, steviosides and tanning substances; the product produces a directional effect on the condition of the liver and lymphatic system, on edema prevention and on metabolic processes optimisation.

3 ex

FIELD: food industry.

SUBSTANCE: invention relates to food industry and may be used as a dietary food supplement; the dietary food supplement contains a fine ground mixture of dry drug raw materials. The raw material contains ingredients taken in the following ratio wt %: currant leaves - 16-36, dandelion root - 7-27, burdock root - 4-24, birch leaves - 4-24, extract of holy thistle seeds - 2-22, dogrose fruits 2-12, bergenia leaves -2-12.

EFFECT: invention allows to produce a dietary product, being a powerful source of flavonoids, arbutin and tanning substances; the product produces a directional effect on the organism cleaning, on the condition of the lymphatic system, on edema prevention with an attenuated impact on vital organs.

2 ex

FIELD: food industry.

SUBSTANCE: invention relates to food industry and can be used while producing high-quality biologically active supplements (BAS) for food. The phospholipid dietary food supplement with hypolipidemic properties is a phospholipid product. The product is prepared by way of hydrating unrefined high-oleic sunflower oil by a water solution of monosubstituted sodium citrate with a concentration of 1.0-4.0%. The said water solution is preliminarily treated in alternating electromagnetic field with a magentic induction of 0.1-0.4 T at a temperature of 30-50°C. Then the prepared phospholipid emulsion is separated from the hydrated oil and dried with the target finished product production.

EFFECT: phospholipid dietary supplement obtains hypolipidemic properties due to application of soft production modes providing for maximally native preservation of food physiologically functional ingredients such as phospholipids including phosphatidylcholines, phosphatidylethanolamines, phosphatidylserines and phosphatidyl inositols, tocopherols and β-carotene.

3 tbl, 3 ex

FIELD: food industry.

SUBSTANCE: invention relates to food industry and may be used to produce high-quality biologically active supplement (BAS) used for direct consumption as a preventive and dietary treatment measure, and also for development of special-purpose food products. BAS to food having hypocholesteremic properties represents powder of melon pulps. Powder is produced by means of melon pulp drying down to moisture of 8-10% and further grinding in thin film rotating along spiral and having thickness of 0.1-0.5 mm at the pulsating gradient of pressure of 5-15 MPa and temperature of 20-25°C.

EFFECT: invention makes it possible to produce additive with high hypocholesteremic properties in stated regimes.

1 tbl, 3 ex

FIELD: food industry.

SUBSTANCE: invention relates to food industry and may be used to produce high-quality biologically active supplement (BAS) used for development of special-purpose food products. BAS to food having anti-inflammatory properties for gastrointestinal tract diseases represents powder of beans. Powder is produced by means of beans drying down to moisture of 13-15% and further grinding in thin film rotating along spiral and having thickness of 0.1-0.5 mm at the temperature of 30-50°C and pulsating gradient of pressure of 50-60 MPa.

EFFECT: invention makes it possible to produce additive with high activity of anti-inflammatory properties by stated regimes.

1 tbl, 3 ex

FIELD: food industry.

SUBSTANCE: invention relates to food industry and may be used to produce high-quality biologically active supplement (BAS) used for direct consumption as a preventive and dietary treatment measure or for development of special-purpose food products. BAS to food having antioxidant properties represents powder of melon pulps. Powder is produced by means of melon pulp drying down to moisture of 8-10% and further grinding in thin film rotating along spiral and having thickness of 0.1-0.5 mm at the pulsating gradient of pressure of 5-15 MPa and temperature of 20-25°C.

EFFECT: invention makes it possible to produce additive with pronounced antioxidant properties.

1 tbl, 3 ex

FIELD: food industry.

SUBSTANCE: invention relates to food industry and may be used to produce high-quality biologically active supplement (BAS) used for direct consumption as a preventive and dietary treatment measure or for development of special-purpose food products. BAS to food having antitoxic properties represents powder of melon pulps produced by means of their drying down to moisture of 8-10%, further grinding in thin film rotating along spiral and having thickness of 0.1-0.5 mm at the pulsating gradient of pressure of 5-15 MPa and temperature of 20-25°C.

EFFECT: invention makes it possible to produce additive with pronounced antitoxic properties.

1 tbl, 3 ex

FIELD: medicine.

SUBSTANCE: invention belongs to medicine, notably to haematology and cardiology and refers to reduction of spontaneous erythrocytes aggregation in patients with arterial hypertension and dislipidemy. To achieve this, combination of hypolipidemic diet with dosed different physical exercises, daily swimming during at lest 40 minutes in the middle of the day is used. Additionally is administered 10 mg of lisinopril in the morning once daily and simvastatin 20 mg after supper once daily. Course of treatment is 2 months.

EFFECT: method ensures correction of spontaneous erythrocyte aggregation in this group of patents and results risk decrement of such thrombotic complications as myocardial infarction, insult and thromboses of different localisation.

1 tbl, 2 ex

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