Method of hestosis treatment for pregnant

FIELD: medicine.

SUBSTANCE: invention concerns medicine, particularly obstetrics and hestosis treatment for the pregnant. Method involves endovascular laser irradiation of blood for six days. Further, polyphepan is administered internally for eight days in the dosage of 0.5 g per kg of pregnant body weight for 3-4 times per day.

EFFECT: therapeutic effect with reduced treatment duration and medication load on organism of the pregnant due to the selected regimen.

1 ex

 

The invention relates to medicine, namely to obstetrics and gynecology, and can be used in the treatment of gestosis.

There is a method of treatment of preeclampsia Sudarikov Mrs x, the Sevastianova O.Y, Pronina T.A. (patent No. 2255776, 2005). This is transcutaneous laser irradiation of the kidneys during pregnancy 30-33 weeks. However, this method does not account for the pathogenesis and possible early (from 20 weeks of gestation) the development of preeclampsia.

There is a method of treatment of preeclampsia Posiseeva L.V., Babakova L.A., Bazhenova M., Panova I.A. (application No. 98104564, published in 2000). The problem is that acupuncture is an invasive and painful procedure. Pregnant women with preeclampsia have increased nervno-mental lability, in this regard, the use of laser puncture in this pathology is not desirable. Also, the method requires the use of sterile or disposable needles.

There is a method of treatment of preeclampsia Khamaganova OR, Evtyugina IV with the application of the enteric sorbent effect Lactofiltrum 2 tablets three times a day an hour before meals for 10-12 days (Syndrome of endogenous intoxication in gestosis, principles of diagnosis and treatment. - Proceedings of the VI Russian forum "Mother and child". - 2004 - s-239).

There is a method of treatment of preeclampsia occurring on the background of nonspecific lung diseases, concomitant use of auto is ultrafioletowego irradiation of blood 2-5 sessions per course and enterosorbent of Boliviana (Starokozheva N.A., Diss. CMN - Voronezh, 1997 - 158 C.).

There is a method of treatment of preeclampsia Assedness and others (patent No. 2.154446 C2, published in 2000) the use of intravascular laser irradiation of blood in 20 minutes a day seven times on the course.

There is a method of treatment of preeclampsia Torchinov A.M., Zahilova YEAR, Austevoll LN. and others with the use of enterosorbent "POLYSORB" 3-4 gr. three times a day an hour before meals for 10-12 days.

The prototype is a method of treatment of preeclampsia mild You a combination of ultraviolet irradiation of blood 2-5 sessions per course and enterosorbent of Politeama one tablespoon three times a day for 10-12 days (the Effects of the introduction of efferent therapy for pregnant women with preeclampsia on the state of the newborn. Efferent therapy. - 2000. - V.6. No. 3. - P.46-51).

The objective of the invention was to develop an effective method of treatment of preeclampsia.

Technical result achieved when using the invention, to improve the results of treatment of preeclampsia, reduced drug load, the improvement of rheological properties of blood, reducing the level of endogenous intoxication, decreased coagulation properties of blood, normalization of processes of lipid peroxidation, stimulation of immunity, the prolongation of pregnancy.

The proposed method of treatment is as follows: hold endovascular laser irradiation of blood (ELOC) on the apparatus ALOKA-1 for 30 minutes once a day from the 1st to the 6th day of treatment, then for eight days enterosorption drug polifan 0.5 g/kg of body weight per day an hour before meals three or four times a day, which is stirred in 50 ml of water. The total course of treatment is 14 days.

The wavelength of the laser radiation of 0.63 μm, the laser power at the output of the fiber is not less than 1 mW. Manufacturer Politeama is JSC "Syntec" St. Petersburg, Russian Federation. Drug polifan selected taking into account the fact that it is readily available, is relatively cheap. It has a high sorption activity and non-specific detoxification effect. In addition to bacterial toxins, heavy metals, drug absorbs too much of some products of metabolism, including bilirubin, cholesterol, urea, metabolites responsible for the development of endogenous intoxication. As a result of ALOK observed favorable changes in the lipid composition of red blood cells, expressed in increased levels of phospholipids. When this normalized aggregation properties, oxygen transport function of erythrocytes. Be improved rheological and reduced coagulation properties of blood, normalization of processes of lipid peroxidation, stimulation of the immune system.

Treated with 60 pregnant women with preeclampsia. Of these 31 women diagnosed with hydrops, 19 - nephrop the party of the first degree, 10 - nephropathy II degree.

The use of ALOK and enterosorption helped to increase the effectiveness of the treatment of preeclampsia by reducing the degree of endogenous intoxication, improve the rheological properties of blood.

Example 1. The pregnant 32 years, first pregnancy, first baby. Nephropathy first degree diagnosed with 34 weeks of gestation. Hospital initiated conventional therapy: anti-hypertensive, infusion, restorative therapy, applied disaggregants. Assigned to endovascular laser irradiation of blood in six days, then enterosorption polyphepanum for eight days. On day 3, blood pressure stabilized, improved General condition, sleep, diuresis. Pregnant 14 days discharged home. Childbirth has occurred through the birth canal during the period of 39 weeks. The post-operative period was uneventful and was discharged home on the 5th day with the child.

Thus, this method of treatment is effective for edema, nephropathy I and II degree. The proposed method made it possible to prolong the pregnancy, to reduce drug load, to reduce the frequency of abdominal delivery.

The simplicity and accessibility of this treatment method can be implemented in all health care institutions.

Treatment of preeclampsia pregnant women, including the irradiation of blood and enterococi what polyphepanum 3-4 times a day, characterized in that conduct intravascular laser irradiation of blood in six days, then enter polifan inside of 0.5 g/kg body weight of pregnant within eight days.



 

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2 ex

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2 ex, 2 tbl

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