Pain management in herniated disks

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to laser therapy. The first stage of the therapy involves introduction of medicines and intravenous laser blood exposure by installing a needle in one solution transfusion system for quartz fibre of diametre 0.7 mm through which the patient is exposed to helium-neon laser of power 1.2 mW at exposition 90 minutes within seven daily procedures. The second stage includes paravertebral block within herniated disk localisation in projection of herniated disk. Quartz fibre of diametre 0.7 mm is introduced through a puncture needle to the level of surface musculofascial layer. Injection of solution is immediately followed with irradiation with helium-neon laser of power 1.2 mW at exposition 80 minutes within seven daily procedures. Medicines within solution transfusion system are as follows: Trental 5 ml, Actovegin 5 ml, 15% Xantinol Nicotinate 2 ml, vitamin B1 2 ml alternated with vitamin B6 2 ml, 5% vitamin C 3 ml dissolved in physiologic saline 150 ml. Paravertebral block of the first day includes 5% glucocorticoid Diprospan 1 ml combined with 2% Lidocaine. For the following days 2% Lidocaine is used.

EFFECT: method allows terminating inflammatory process, ensuring stable pain management.

3 ex

 

The invention relates to medicine, namely to laser therapy, and may find application in the treatment of complicated forms of the disease degenerative disc disease, namely intervertebral hernias, using low-intensity helium-neon lasers.

Known "Method of sighting laser decompression of intervertebral discs" (Russian patent No. 2296509, AV 6/00, AK 49/04, A61N 5/067, priority, 14.10.2005, published 10.04.2007,), including the installation of a puncture needle into the damaged disc, the introduction of a needle of the laser fiber, the formation of channels in the disk under the action of laser and conducting direct retrograde vaporization of disc herniation under the control of the visualization tools. Vaporization hernia repair performed under x-ray contrast control - discography, or myelography, or diskomalaria with the introduction of a contrast agent, respectively, in the disk or in a dural bag or disc and dural bag.

The method relates to laser surgery and is used in the treatment of neuroorthopedics diseases of the spine. However, this invention is directed to a process of lookup operation reliable information on the localization of the hernia formations with varying degrees of destruction of the disk while reducing the radiation load on the patient, and will also allow you to simplify operation and reduce the time to carry it out without compromising the quality of the Wu. It uses high-intensity laser radiation, which in turn leads to increased radiation load on the patient.

Also known for the treatment of discogenic sciatica" (Russian patent No. 2174022, A61N 5/067, prior. 27.12.2000, publ. 27.09.2001, by exposure to high-intensity pulsed laser radiation with fields 1-5 4-8 cm in diameter remotely wavelength 580-600 nm at a pulse repetition frequency of 1-3 Hz, power density of the radiation pulse 10 W/cm2- 200 kW/cm2at a dose of 0.2 to 25 j/cm2within 40 20 min and individualization of the way through the adjustment of the above parameters in the specified ranges during the course of treatment 4 to 7 sessions and repetition in 2-3 weeks.

The treatment begins with a skin effect on the main focus with the focus of the field of irradiation on the herniated disc. If necessary, use the advanced or additional fields of irradiation with the inclusion of paravertebral or remote radicular impact zones. However, improving the efficiency and reducing the duration of treatment in this way is achieved through the use of high-energy pulsed laser radiation and uses methods of laser therapy, as it is controlled cutaneous planning the radiation field.

Also known "Method of treatment is degenerative-dystrophic diseases of the spine and large joints (RF, patent for invention No. 2294227, A61N 5/067 A61K 38/48, AR 19/02, priority 02.11.2005, published 27.02.2007, including the irradiation of the affected area of low-intensity laser radiation. Irradiation is carried out helium-neon laser with a wavelength of 0.63 µm, the power density of 10 mW/cm2, exposure time exposure of 10 min, the number of sessions 10 after a preliminary application to the skin of the affected area single-layer gauze napkins soaked in 1%solution of karipazim.

When conducting photophoresis caripazym helium-neon laser is mutual potentiation of anti-inflammatory action of laser radiation and metabolic effect caripazym. This leads to simultaneous exposure to multiple pathogenetic links RSD: synovitis, myositis, neuralgia. In the breaks the vicious circle of pain spasm periarticular muscles, decreases myogenic compression of the articular surfaces, is non-specific adaptogenic effect. Laser photophoresis can be performed for patients with an artificial pacemaker, with severe comorbidity. However, low-intensity laser therapy in this way is used for the treatment of osteochondrosis and for the treatment of osteoarthritis deformans. This method is not intended for the treatment of intervertebral disc herniation. Additionally, the treatment is high-intensity laser with a high power density of the radiation.

The closest in technical essence and the achieved effect to the claimed method is a Method of treatment of hernias and protrusions of disks of the lumbar spine" (Russian patent No. 2277393, AV 18/20, AV 17/56, priority 19.11.2002, published 10.06.2006 g), is the impact of laser irradiation on the pathologic lesion of the spine. In an epidural space through the posterior sacral foramen SI or beastity period depending on the level of destruction enter the guide for nanovolokno quartz fiber with diameter from 0.8 to 1.0 mm, through which irradiate an epidural space of a helium-neon laser in the visible range, the exposure time of the laser 30 minutes

When this pathoetiology treatment laser radiation acts directly on the lesion, and not at the segmental or reflex zone, there is no scattering of laser radiation in different directions and use the visible (red) laser and the ability to focus the laser beam. However, this method of treatment involves using high-energy laser device, which increases the radial load on the patient and assumes equipped operating with a team of neurosurgeons, emergency wards, and does not exclude serious donkey is jnani during manipulation near the spinal cord.

The task, which is aimed by the invention, is to increase the efficiency of treatment by applying laser technology, aimed at the relief of the inflammatory process that leads to permanent relief of pain, and in some cases, to decrease and disappearance of the herniated disk.

The technical result that can be obtained from the use of the invention is to simplify the process of treatment by its implementation in the clinic under local anesthesia, virtually eliminating any complications, reduced recovery time to three months, in the absence of disability, the ability to work without limitations of physical activity.

The problem is solved by a method for relieving pain in the intervertebral hernias, is the impact of laser irradiation helium-neon laser with a wavelength of 0,6328 μm on the pathologic lesion and the introduction of drugs, at the first stage are at the same time intravenous medication and laser irradiation of blood through one system transfusion solution by installing a needle for a quartz optical fiber with a diameter of 0.7 mm, the irradiation of blood hold helium-neon laser power of 1.2 mW exp is a position 90 minutes daily, seven procedures. And at the second stage the patient is in the zone of localization of disc herniation perform paravertebral blockade in the projection of intervertebral disc herniation and through the puncture needle is injected quartz optical fiber with a diameter of 0.7 mm to the level of the superficial muscle located fascial layer. Immediately after introduction of the solution carry out the irradiation of this section of the helium-neon laser power of 1.2 mW with an exposure time of 80 minutes, every day, seven procedures In this type of drugs in the system of the transfusion solution include solutions trental 5 ml, aktovegin 5 ml, 15% xantinol of nicotinate 2 ml of vitamin b-1 2 ml with alternating vitamin b-6 2 ml, vitamin C 5% to 3 ml by dilution with saline 150 ml, and paravertebral blockade perform on the first day using 5% glucocorticoid-diprospan 1 ml together with 2% lidocaine and in the days that followed her perform 2% lidocaine.

Thus, the achievement of the technical result is achieved due to the use nizkoenergeticheskogo helium-neon laser power of 1.2 mW in the technology of laser therapy. Along with intravenous irradiation of blood in this method of treatment proposed to apply laser radiation through the puncture needle on certain muscles projection intervertebral disc herniation with exposure time of 80 minutes.

With whom persons treatment is implemented as follows.

Spend influence of low-intensity helium-neon laser radiation on the blood. By means of venipuncture, usually through the cubital vein injected drugs through the system transfusion solution containing the solution trental 5 ml, aktovegin 5 ml, 15% xantinol of nicotinate 2 ml of vitamin b-1 2 ml with alternating vitamin b-6 2.0 ml, vitamin C 5% to 3 ml by dilution with saline 150 ml. Simultaneously through this same system transfusion solution, installed intravenous, conduct an impact on the blood of laser radiation by installing the same system transfusion solution standard needle with a diameter of 0.9 mm and the introduction into it of a quartz optical fiber with an external 0.7 mm in diameter (inner diameter 400 μm). To the optical fiber connected helium-neon laser with a power of radiation of 1.2 mW. Exposure time is 90 minutes. This procedure is performed daily. The total number of procedures - seven.

The next day after the above-mentioned procedures, the patient is paravertebral blockade disposable needles with a diameter of 0.9 mm in the projection of intervertebral disc herniation. The first day is used 5% of the glucocorticoid-diprospan 1 ml together with 2% lidocaine - 2 ml In the following days the blockade is 2% lidocaine.

Immediately after the introduction of a solution through a needle, wodis the quartz optical fiber with an outer diameter of 0.7 mm and an inner diameter of 400 microns - to the level of the superficial muscle located fascial layer. To the optical fiber connected helium-neon laser with a radiation power of 1.2 mW. Exposure time is 80 minutes. This procedure is performed daily. The total number of procedures - seven.

After three months, all patients regardless of clinical effect is similar to a second course of treatment.

The effectiveness of the method was studied in 12 patients with disc herniation. Of these two patients hernia was localized in the cervical spine, at 10 in the lumbar spine. The age of patients from 42 to 68 years, of which 6 men and 6 women.

In the cervical spine disc herniation was observed in the C-4/C-5, C5/6. In the lumbar spine disc herniation was observed in L-4/L-5, L-5/L-6. Herniated disc in the cervical region varied from 0.4 to 0.6 cm, lumbar ranges from 0.6 to 1.2, see

For the purpose of diagnosis all patients underwent radiography in two projections and magnetic resonance imaging (MRI).

All patients, without exception, within 3-5 years was in outpatient and inpatient treatment on this occasion without significant effect. In six cases registered refusal of surgical treatment from the patient. Thus, the method of treatment helium-neon laser, laser technology, was used exclusively after the anee held ill treatment has already proven methods.

To illustrate examples of specific applications of the method of treating the above patient, i.e. with application of low-intensity helium-neon laser on the basis of minimally invasive technology.

Example 1.

Ger s CENTURIES, came in 2006 with complaints of constant aching pain in the lumbar-cross the region, aggravated by physical exertion in the morning. Considers himself ill for more than 20 years, when after overload training first appeared pain in the lumbar region. The last 5 years the pain has intensified and become permanent. In 2001, he was examined in the 2nd multidisciplinary hospital in Saint-Petersburg. MRI confirmed herniated discs L-4/L-5, L-5/S-1 with a diameter of 3 mm and 6 mm, respectively. Each year in inpatient and ambulatory settings and conducts courses of therapy without significant effect.

Neurological status: eye movements in full, no nystagmus. The tongue in the midline. Muscle strength in full. Tendon reflexes live, absent ankle reflex on the left. Flattened lumbar lordosis. Pronounced protective defense back at the lumbar level. Symptom Lasaga left 50%right 30%.

Patients received treatment with the use of helium-neon laser power of 1.2 mW through a puncture in the cubital vein was injected solution trental 5 ml, aktovegin 5 ml, 15% of xantinol is kohinata 2 ml, vitamin b-1 2 ml with alternating vitamin b-6 2.0 ml, vitamin C 5% to 3 ml by dilution with saline 150 ml system pouring the solution through a standard needle with a diameter of 0.9 mm is introduced quartz optical fiber with an outer diameter of 0.7 mm (inner diameter 400 μm). To the optical fiber connected helium-neon laser with a power of radiation of 1.2 mW. Exposure time is 90 minutes. This procedure is performed daily. The total number of procedures - seven.

The next day after the above-mentioned procedures, the patient is paravertebral blockade disposable needles with a diameter of 0.9 mm in the projection of intervertebral disc herniation. The first day is used 5% of the glucocorticoid-diprospan 1 ml together with 2% lidocaine 2 ml, in the following days the blockade was performed with 2% solution of lidocaine 2 ml Immediately after the introduction of a solution through the puncture needle was introduced into a quartz optical fiber with an inner diameter of 400 μm to level predlagash muscles with subsequent connection HeNe laser power of 1.2 mW with an exposure time of 80 minutes. The procedure was carried out daily, the total number of procedures 7.

In the course of treatment was stopped back pain in full. After 3 months of repeated course of treatment.

Viewed in may 2007. No complaints. Palpation of the spinous processes 5, 6, lumbar and sacral POS is ankov painless. The muscles of the lower limbs missing. The patient is actively engaged in physical training, playing football without pain.

Example 2.

Should VA V.B. have been, born in 1952, discogenic ischemic radiculomyelopathy. Herniated discs. C4-C5/C6-C7, contracted sharply in 2000. Since 2000, was carried out appropriate therapy for the underlying disease in outpatient and inpatient conditions, was carried out rehabilitation activities without significant dynamics improve. The tendency of deterioration of the patient over time, which resulted in a partial reduction of pain syndrome on the background of therapy and the appearance of pain in the cervical spine almost immediately after treatment. Turned into a medical institution of the place of residence in 2003 with complaints of pain in the cervical spine, which iradionet in the right hand weakness and numbness in his right hand.

Neurological status: consciousness is clear, the pupils uniform, reaction to light and installation of living. Movement of the eyeballs in full. Nystagmus no. The sensitivity on the person saved. The language in the midline, the face is symmetrical. Hyperesthesia on C6 on the right. Positive sympton of Venderovich. Pathological stop signs. The reflexes of the lower extremities live, without extension reflex zones. Muscle tension in the neck. Mr-tomogr the FFL. The series of control Mr tomograms T1 weighted and T2 in three dimensions compared to MRI study 11.12.2001, without the expressed dynamics: saved straightening of lordosis with a tendency to the formation of kyphosis. The height of the disk of the investigated area and the signals on T2 is reduced. Rear medial-paramedicine herniated disc C4-C6 propagating in the intervertebral holes on both sides in the same sizes. Dorsal protrusion of disks C3-C4, C6-C7. The lumen of the spinal canal is narrowed at the level of the herniation and protrusion of disks, spinal cord structural, signal (in modes T1 and T2) is not modified.

Conclusion: MRI pattern of degenerative changes of the cervical spine, acute disk herniation (C4-C6).

A course of therapy: treatment using a helium-neon laser power of 1.2 mW through a puncture in the cubital vein was injected solution trental 5 ml, aktovegin 5 ml, 15% of xanthineolytica 2 ml of vitamin b-1 2.0 ml with alternating vitamin b-6 2.0 ml, vitamin C 5% to 3 ml by dilution with saline 150 ml system pouring the solution through a standard needle with a diameter of 0.9 mm is introduced quartz optical fiber with an outer diameter of 0.7 mm (inner diameter 400 μm). To the optical fiber connected helium-neon laser with a power of radiation of 1.2 mW. Exposure time is 90 the minutes. This procedure is performed daily. The total number of procedures 7.

The next day after the above-mentioned procedures, the patient was performed paravertebral blockade disposable needles with a diameter of 0.9 mm in the projection of intervertebral disc herniation. The first day is used 5% of the glucocorticoid-diprospan 1 ml together with 2% lidocaine 2 ml, in the following days the blockade was performed with 2% lidocaine solution to 2 ml Immediately after the introduction of a solution through the puncture needle was introduced into a quartz optical fiber with an inner diameter of 400 μm to level predlagash muscles with subsequent connection HeNe laser power of 1.2 mW with an exposure time of 80 minutes. The procedure was carried out daily, the total number of procedures 7.

After a course of therapy in 10-12 days were stopped completely pain syndrome. A follow-up examination one year later showed that pain was absent.

Example 3.

Would s B.C., 62, Diagnosis: Sideleva herniated disc L-4/L-5 to 6 mm, compressicauda dural bag and left L-5 nerve root. Comorbidities - surface proktoshigmoidit, peptic ulcer in remission, hemangioma Th-7,10 vertebrae. From the anamnesis it is known that first appeared pain in the lumbar spine in 1990, after the examination diagnosed with lumbar osteochondrosis with severe pain what andromon. Herniated disc L-4/L-5 detected only in 2001, after performing MRI. Registered, was carried out appropriate therapy for outpatient and inpatient level, the number of treatment and rehabilitation activities in specialized hospitals. It should be noted that completely arrest the pain was not possible. According to the patient, the pain was dulled, causing limitation in physical activity. Over time the pain has intensified. The patient asked in 2003 as per the place of residence with complaints of pain in the lumbar spine. The nature - aching pain, aggravated by movement and axial load, intractable analgesics. Palpation reveals a sharp muscle tension and soreness L-4/L-5. Neurological status: consciousness clear, contact, oriented in time and space correctly. Emotionally stable. Eyes rounded with a smooth edge, D=S. the Expression (direct and friendly) living and symmetric. Accommodation and convergence are saved. Movement of the eyeballs in full. Nystagmus and diplopia no. Face symmetrical. The tongue in the midline. Swallowing and foncia not violated. The Palatine and pharyngeal reflexes are not changed. The strength of the muscles in the hands satisfactory. Muscle tone in the legs is increased, the power is reduced, more in the left leg. Deep reflexes in the legs quickened, simmetry the us, extension reflex zones, clonus stop, more to the left. The voltage of the long back muscles more to the left. Positive sympton Lasaga (right 30 left 40). Meningeal signs. The series of MRI tomograms of the lumbosacral spine is the Central dorsal herniated disc L-3-4 to 2 mm with partial compression of the nerve roots on both sides, L-4-5 up to 3 mm with compression of the anterior chamber of dural SAC and nerve roots on both sides, L-5-S-1 to 6 mm with compression of the nerve roots on both sides.

Patients received therapy, which was in the course of treatment using a helium-neon laser power of 1.2 mW by performing puncture the cubital vein into which was introduced a solution trental 5.0 ml, aktovegin 5.0 ml, 15% xantinol of nicotinate 2.0 ml, vitamin b-1 2.0 ml with alternating vitamin b-6 2.0 ml, vitamin C 5% to 3 ml by dilution with saline 150 ml system pouring the solution through a standard needle with a diameter of 0.9 mm was introduced into a quartz optical fiber with an outer diameter of 0.7 mm (inner diameter 400 μm). To the optical fiber connected helium-neon laser with a power of radiation of 1.2 mW. Exposure time is 90 minutes. This procedure is performed daily. The total number of procedures - seven.

The next day after the above-mentioned procedures to patients who NTU is paravertebral blockade disposable needles with a diameter of 0.9 mm in the projection of intervertebral disc herniation. The first day is used 5% of the glucocorticoid-diprospan 1 ml together with 2% lidocaine - 2 ml In the following days the blockade was performed with 2% lidocaine solution to 2 ml Immediately after the introduction of a solution through the puncture needle was introduced into a quartz optical fiber with an inner diameter of 400 μm to level predlagash muscles with subsequent connection HeNe laser power of 1.2 mW with an exposure time of 80 minutes. The procedure was carried out daily, the total number of procedures 7.

After therapy pain syndrome was stopped. Surveillance for 5 years: pain is absent. This patient is a driver and conducts a comprehensive way of life.

A new positive result of the application of the proposed method is to increase the effectiveness of treatment due to the achievement of the following indicators: fully docked pain syndrome associated with symptomatic disc herniation - lumbago, lumbar ischialgia, ishialgii. Follow-up was from 1 year to 7 years. During this time there was no recurrence in any of the patients. Three patients underwent repeat MRI. A herniated disc is not detected. Currently, all patients lead an active lifestyle, work without limitations of physical activity, without disability. As an example, one of the patients at the present time who I work as a tractor driver, the other bulldozer.

Treatment is possible and appropriate to use in the outpatient setting due to the simplicity of its execution.

The most effective technology in this field of medicine today can be considered the treatment of complicated forms of degenerative disc disease using low-intensity helium-neon lasers. In this way a helium-neon laser with a power of 1.2 mW is used in non-surgical techniques in the treatment of diseases of the spine. Laser technology is the most advanced and effective technology for the treatment of spinal pathologies, without injuring healthy tissue of the spine. Laser therapy can significantly reduce the recovery time and completely arrest the pain. Thus, in this way increasing the efficiency of the treatment is aimed at relief of the inflammatory process that leads to lasting relief of pain, and in some cases, reduction or disappearance of a hernia of a disk.

Method of relieving pain in the intervertebral hernias, is the impact of laser irradiation helium-neon laser with a wavelength of 0,6328 μm on the pathologic lesion and the introduction of drugs, characterized in that in the first stage are at the same time intravenous administration of drugs lazernoe irradiation of blood through one system transfusion solution by installing a needle for a quartz optical fiber with a diameter of 0.7 mm, blood irradiation spend a helium-neon laser power of 1.2 mW with an exposure time of 90 minutes daily in the amount of seven procedures, and at the second stage the patient is in the zone of localization of disc herniation perform paravertebral blockade in the projection of intervertebral disc herniation and through the puncture needle is injected quartz optical fiber with a diameter of 0.7 mm to the level of the superficial muscle located fascial layer and immediately after introduction of the solution carry out the irradiation of this section of the helium-neon laser power of 1.2 mW exposure 80 min daily in the amount of seven treatments, with drugs in the system of the transfusion solution include solutions trental 5 ml, aktovegin 5 ml, 15% xantinol of nicotinate 2 ml, vitamin B1 2 ml with alternating vitamin B6 2 ml, vitamin C 5% to 3 ml by dilution with saline 150 ml, and paravertebral blockade perform on the first day using 5% glucocorticoid-diprospan 1 ml together with 2% lidocaine, and in the days that followed her perform 2% lidocaine.



 

Same patents:

FIELD: medicine.

SUBSTANCE: therapy of secondary lower limb lymphodema refers to medicine, namely to clinical lymphology. The oatient is exposed to laser light of wavelength 0.6328 mcm combined with intravenous laser irradiation of power 1.2 mW and exposition 90 minutes and intravenous introduction of medicine solutions: Trental, Actovegin, Pheopolyglukine, vitamin B, C complexes, 0.15% xantinol nicotinate. Procedures are daily at seven procedures per course.

EFFECT: therapy provides stable reduction of secondary lower limb lymphodema without therapeutic by-effects, prevents recurrence.

2 cl, 2 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, to neurology. The therapy involves taking the medicines improving cerebral blood circulations. Pharmacotherapy is combined with exposure to laser light within anconeus and popliteal fold regions. Laser puncture covers the points VB 20 and VB 21 symmetrically downright. Laser light is characterised with wavelength 0.89 mcm, power 3 mW and frequency 600 Hz. Herewith light exposure is 1 minute per each point and 2-3 minutes per elbow and popliteal folds. Therapeutic course is 10 days twice every second month.

EFFECT: method reduces treatment time.

3 ex, 1 tbl

FIELD: medicine.

SUBSTANCE: invention relates to medicine, oncology, surgery, radiology, physical therapy and can be used for treating patients with larynx cancer. Area of radiation and surrounding tissues is exposed to infrared laser irradiation. From first day of radioreaction diagnostics, exposure to infrared laser irradiation with constant magnetic field with magnetic induction intensity within 20 mTa, recurrence frequency of pulse laser irradiation of infrared spectrum within 80 Hz, power 0.5-1.0 W on all zone of irradiation is performed with defocused ray for 30-120 seconds. Course includes 3-8 procedures with further application on irradiation zones and intake of a teaspoon of cedar nut oil and before going to bed daily during the whole course of radiation therapy.

EFFECT: method allows to increase efficiency of treatment of early radioreactions and prevent development of later radiation damage reducing severity and frequency of their development.

2 ex

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to ophthalmology. Laser stroboscopy is carried out during 5 days, 2 times a day with 1 hour interval. First 10 minutes each eye is influenced in turn, then for 5 minutes both eyes are influenced simultaneously. Distance to speckle is 1 m.

EFFECT: recovering binocular functions with elimination of anisoaccomodation, enhancing binocular interaction, increasing visual acuity.

3 cl, 2 ex

Epilepsy management // 2353411

FIELD: medicine.

SUBSTANCE: invention refers to medicine and aims at epilepsy management. Carotid and vertebral arteries are sequentially exposed to IR laser light, infra-red laser radiation to the right and to the left each for 5 minutes. Frontal, temporal, parietal and occipital lobes are exposed to magnetic field and microwave radiation to the right and to the left each for 3 minutes. And visual analyser is exposed to IR waves within 30 minutes. It is combined with electroencephalographic training with course of treatment 15 procedures.

EFFECT: disclosed method allows for improved mental measurements, relieved remove proneness to convulsive activity, suppressed epileptogenic zones, improved metabolic and energy cerebral processes, normalised cerebral blood flow regulation, recovered cortical neurodynamic disorders.

1 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, oncology and to be used for neoadjuvant chemoradiotherapy in the patients suffering from thoracic oesophagus cancer. Said therapy is ensured by introduction of cisplatin and leucovorin, and continuous intravenous infusions of fluorouracil dosed 300 mg/m2. Cisplatin solution is introduced intravenously drop-by-drop and dosed 6 mg/m2 daily once a day within 1 hour. Leucovorin is injected intravenously jet-like and dosed 30 mg/m2. Radiotherapy involves daily fractions 3 Gy to total basic dose 30 Gy. The course dose of fluorouracil is 3600 mg/m2, of cisplatin is 72 mg/m2, of leucovorin 360 mg/m2. Chemotherapy and radiotherapy are to be started the same day.

EFFECT: disclosed method allows for considerably reduced toxicity of treatment to be continuous, treatment of the patients originally of bad performance status, for doubly reduced time of neoadjuvant treatment with maintaining high clinical effectiveness.

2 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, urology, physiotherapy and to be used in the patients suffering from chronic pyelonephritis accompanied with chronic prostatitis and chronic cystitis. The method involves taking the mineral water of the Slavjanovsky source dosed 3 - 5 ml per kg of body weight, combined with carbonic mineral baths 35-37°C for 15 minutes 3 times a day, № 8-10, mud "panties" at 40-42°C within 30 minutes to 1.5 hours, prostate massage № 8-10, additionally 50-60 minutes later followed with electropulse therapy combined with exposure to laser magnetic rays. Electropulse therapy involves low-frequency, low-voltage pulse current with a spherical unipolar electrode. Exposure is contact, labile, clockwise and located at skin projection of ascending, transverse and descending large intestine at frequency 30.2 Hz within 8-10 minutes. The course of treatment is 10-12 procedures.

EFFECT: method improves life quality of the patients both in latent phase of inflammatory process, and in mild and moderate active chronic process.

2 ex, 2 tbl

FIELD: medicine.

SUBSTANCE: invention concerns ophthalmology and is intended for treatment of infectious diseases of a cornea. Photodynamic therapy with the use of gel containing an octacation phthalocyanine of zinc in concentration of 1-3 mg/ml, which is applied on a cornea as a photosensitinogen, is performed. The conjunctival cavity is washed out after 30 - 40 minutes and influenced with a laser radiation with a wavelength of 675 nm with a light dose 20 - 60 J/cm2 in of 5 minutes, once a day. 1-8 sessions during each course.

EFFECT: method allows destroying the originator of keratitis in a cell with the maximum safety of surrounding tissues of the cornea.

2 tbl, 3 dwg, 1 ex

FIELD: medicine.

SUBSTANCE: invention concerns medicine, namely, physiotherapy, reflexotherapy. Prior to the beginning of backbone extension acupuncture by the rule "Mother-son" is performed. In 3-5 days the backbone is simultaneously influenced with a magnetic-laser radiation and extension is performed. The magnetic-laser radiation influence is spent in red 630-650 nm and infra-red 890-950 nm ranges with 50 mT intensity of a magnetic field. Backbone extension is spent in mass of a load by 15-30 kg. Total time of the procedure makes 15-20 minutes.

EFFECT: method increases analgetic effect, reduces puffiness and improves microcirculation and trophicity of tissues.

1 ex

FIELD: veterinary.

SUBSTANCE: invention relates to field of veterinary. Method includes preliminary feeding medical herb flour to cattle on the background of main diet. After feeding with medical herb flour, cattle is subjected to single low-intensity magnet-laser exposure with semi-conductor laser "Isel-Victoria" on the region of spine from withers to tail attachment from both sides. Exposure is performed for 5-10 minutes from each side, for cows from distance 10-12 cm, for calves from distance 3-4 cm from middle sagittal line. Exposure is performed with the following radiation modes: wave length 0.85-0.89 mcm, laser impulse power 3.5 mW -5.0 W, pulse repetition frequency -50-80 Hz, energy dose - 0.002-0.024 J/cm2, power density - 0.1-0.3 mW/cm2 .

EFFECT: method allows to remove heavy metals from cattle organism in short time.

3 ex

FIELD: medicine.

SUBSTANCE: method involves introducing 0.1-0.3 ml of photosensitizing gel preliminarily activated with laser radiation, after having removed neovascular membrane. The photosensitizing gel is based on a viscoelastic of hyaluronic acid containing khlorin, selected from group containing photolon, radachlorine or photoditazine in the amount of 0.1-2% by mass. The photosensitizing gel is in vitro activated with laser radiation having wavelength of 661-666 nm during 3-10 min with total radiation dose being equal to 100-600 J/cm2. The gel is introduced immediately after being activated. To compress the retina, vitreous cavity is filled with perfluororganic compound or air to be further substituted with silicon oil. The operation is ended with placing sutures on sclerotomy and conjunctiva areas. Compounds like chealon, viscoate or hyatulon are used as viscoelastic based on hyaluronic acid. Perfluormetylcyclohexylperidin, perfluortributylamine or perfluorpolyester or like are used as the perfluororganic compound for filling vitreous cavity.

EFFECT: excluded recurrences of surgically removed neovascular membrane and development of proliferative retinopathy and retina detachment; retained vision function.

3 cl, 5 dwg

FIELD: medicine.

SUBSTANCE: method involves making incision in conjunctiva and Tenon's capsule of 3-4 mm in size in choroid hemangioma projection to sclera 3-4 mm far from limb. Tunnel is built between sclera and Tenon's capsule to extrasclerally introduce flexible polymer magnetolaser implant through the tunnel to the place, the choroid hemangioma is localized, after performing transscleral diaphanoscopic adjustment of choroid hemangioma localization and size, under visual control using guidance beam. The implant has permanent ring-shaped magnet in the center of which a short focus scattering lens of laser radiator is fixed. The lens is connected to light guide in soft flexible envelope. The permanent implant magnet is axially magnetized and produces permanent magnetic field of 2-3 mTesla units intensity. It is arranged with its north pole turned towards the choroid hemangioma so that extrascleral implant laser radiator disposition. The other end of the implant is sutured to sclera 5-6 mm far from the limb with two interrupted sutures through prefabricated openings. The implant is covered with conjunctiva and relaxation sutures are placed over it. Light guide outlet is attached to temple using any known method. 0.1-1% khlorin solution is injected in intravenous bolus dose of 0.8-1.1 mg/kg as photosensitizer and visual control of choroid hemangioma cells fluorescence and fluorescent diagnosis methods are applied. After saturating choroid hemangioma with the photosensitizer to maximum level, transscleral choroid hemangioma laser radiation treatment is carried out via laser light guide and implant lens using divergent laser radiation at wavelength of 661-666 nm with total radiation dose being equal to 30-120 J/cm2. The flexible polymer magnetolaser implant is removed and sutures are placed on conjunctiva. Permanent magnet of the flexible polymer magnetolaser implant is manufactured from samarium-cobalt, samarium-iron-nitrogen or neodymium-iron-boron system material. The photosensitizer is repeatedly intravenously introduced at the same dose in 2-3 days after the first laser radiation treatment. Visual intraocular neoplasm cells fluorescence control is carried out using fluorescent diagnosis techniques. Maximum level of saturation with the photosensitizer being achieved in the intraocular neoplasm, repeated laser irradiation of the choroid hemangioma is carried out with radiation dose of 30-60 J/cm2.

EFFECT: enhanced effectiveness of treatment.

4 cl

FIELD: medicine.

SUBSTANCE: method involves creating tunnel between sclera and Tenon's capsule in intraocular neoplasm projection. Intraocular neoplasm localization and size is adjusted by applying transscleral diaphanoscopic examination method. 0.1-0.3 ml of photosensitizing gel based on viscoelastic of hyaluronic acid, selected from group containing chealon, viscoate or hyatulon, is transsclerally introduced into intraocular neoplasm structure using special purpose needle in dosed manner. The photosensitizing gel contains khlorin, selected from group containing photolon, radachlorine or photoditazine in the amount of 0.1-1% by mass. Flexible polymer magnetolaser implant is extrasclerally introduced into the built tunnel in intraocular neoplasm projection zone under visual control using guidance beam. The implant has permanent ring-shaped magnet axially magnetized and producing permanent magnetic field of 3-4 mTesla units intensity, in the center of which a short focus scattering lens of laser radiator is fixed. The lens is connected to light guide in soft flexible envelope. The implant is arranged with its north pole turned towards the intraocular neoplasm so that implant laser radiator lens is extrasclerally arranged in intraocular neoplasm projection zone. The implant light guide is sutured to sclera 5-6 mm far from the limb with single interrupted suture. The implant is covered with conjunctiva and relaxation sutures are placed over it. Light guide outlet is attached to temple using any known method. Visual control of intraocular neoplasm cells is carried out by applying fluorescence and fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, transscleral intraocular neoplasm laser radiation treatment is carried out via laser light guide and implant lens using divergent laser radiation at wavelength of 661-666 nm. The treatment course being over, the flexible polymer magnetolaser implant is removed and sutures are placed on conjunctiva. Permanent magnet of the flexible polymer magnetolaser implant is manufactured from samarium-cobalt, neodymium-iron-boron or samarium-iron-nitrogen. 0.1-1% khlorin solution as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, is additionally intravenously introduced in 2-3 days at a dose of 0.8-1.1 mg/kg and repeated laser irradiation of the intraocular neoplasm is carried out with radiation dose of 30-45 J/cm2 15-20 min later during 30-90 s.

EFFECT: complete destruction of neoplasm; excluded its further growth.

4 cl

FIELD: medicine.

SUBSTANCE: method involves applying transscleral diaphanoscopic examination method for adjusting intraocular neoplasm localization and size. Rectangular scleral pocket is built 2/3 times as large as sclera thickness which base is turned from the limb. Several electrodes manufactured from a metal of platinum group are introduced into intraocular neoplasm structure via the built scleral pocket. Next to it, intraocular neoplasm electrochemical destruction is carried out in changing electrodes polarity with current intensity of 100 mA during 1-10 min, and the electrodes are removed. Superficial scleral flap is returned to its place and fixed with interrupted sutures. 0.1-2% aqueous solution of khlorin as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, is intravenously introduced at a dose of 0.8-1.1 mg/kg. Visual control of intraocular neoplasm cells is carried out by applying fluorescence and fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, transpupillary laser radiation of 661-666 nm large wavelength is applied at a dose of 30-120 J/cm2. the operation is ended with placing sutures on conjunctiva. Platinum, iridium or rhodium are used as the metals of platinum group. The number of electrodes is equal to 4-8. 0.1-1% khlorin solution, selected from group containing photolon, radachlorine or photoditazine, is additionally repeatedly intravenously introduced in 2-3 days at a dose of 0.8-1.1 mg/kg. Visual control of intraocular neoplasm cells is carried out by applying fluorescence and fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, repeated laser irradiation of the intraocular neoplasm is carried out with radiation dose of 30-45 J/cm2.

EFFECT: complete destruction of neoplasm; excluded tumor recurrence; reduced risk of tumor cells dissemination.

3 cl, 3 dwg

FIELD: medicine.

SUBSTANCE: the present innovation deals with treating vascular cutaneous neoplasms, such as nevus flammeus and gemangiomas. Light-thermal impact at energy ranged 39-47 J/sq. cm should be performed in two stages, and between them, 2-3 wk after the onset of vascular resistance at the first stage one should perform beta-therapy daily for 2-3 d at single dosage being 20 g. Then, 3 wk later it is necessary to conduct the second stage of light-thermal impact by starting at energy value being 42 J/sq. cm, not less. The method enables to shorten therapy terms due to applying combined method to affect vascular cutaneous neoplasms.

EFFECT: higher therapeutic and cosmetic effect.

1 ex

FIELD: medicine.

SUBSTANCE: method involves intravitreously introducing two electrodes into intraocular neoplasm after carrying out vitrectomy and retinotomy to expose the intraocular neoplasm. The electrodes are manufactured from platinum group metal. Electrochemical destruction is carried out with current intensity of 100 mA during 1-10 min or 10 mA during 10 min in changing electrodes polarity and their position in the intraocular neoplasm space, and the electrodes are removed. 0.1-1% aqueous solution of khlorin as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, is intravenously introduced at a dose of 0.8-1.1 mg/kg. Visual control of intraocular neoplasm cells fluorescence is carried out by applying fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, intravitreous laser radiation is carried out in parallel light beam of wavelength equal to 661-666 nm is applied at a dose of 30-120 J/cm2.The transformed retina and tumor destruction products are intravitreally removed. Boundary-making endolasercoagulation of retinotomy area is carried out after having smoothed and compressed retina with perfluororganic compound. The operation is finished with placing sutures on sclerotomy and conjunctiva. Platinum, iridium or rhodium are used as the platinum group metals. Another embodiment of the invention involves adjusting position and size of the intraocular neoplasm in trans-scleral diaphanoscopic way. Rectangular scleral pocket is built above the intraocular neoplasm to 2/3 of sclera thickness with its base turned away from limb. Several electrodes are introduced into intraocular neoplasm structure via the built bed. The electrodes are manufactured from platinum group metal. Electrochemical destruction is carried out with the same current intensity in changing electrodes polarity and their position in the intraocular neoplasm space, and the electrodes are removed. Superficial scleral flat is returned to its place and fixed with interrupted sutures. 0.1-1% aqueous solution of khlorin as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, is intravenously introduced at a dose of 0.8-1.1 mg/kg after having carried out vitrectomy and retinotomy. Visual control of intraocular neoplasm cells fluorescence is carried out by applying fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, intravitreous laser radiation is carried out in parallel light beam of wavelength equal to 661-666 nm is applied at a dose of 30-120 J/cm2. The transformed retina and tumor destruction products are intravitreally removed using vitreotome. Boundary-making endolasercoagulation of retinotomy area is carried out after having smoothed and compressed retina with perfluororganic compound. The operation is finished with placing sutures on sclerotomy and conjunctiva. Platinum, iridium or rhodium are used as the platinum group metals. The number of electrodes is equal to 4-8.

EFFECT: reduced risk of metastasizing.

4 cl, 13 dwg

FIELD: medicine.

SUBSTANCE: method involves building tunnel to posterior eyeball pole in inferoexterior and superexterior quadrants. The tunnel is used for implanting flexible polymer magnetolaser implant to the place, the subretinal neovascular membrane is localized. The implant has a permanent magnet shaped as a cut ring and is provided with drug delivery system and a short focus scattering lens of laser radiator connected to light guide. The permanent implant magnet is axially magnetized and produces permanent magnetic field of 5-7 mTesla units intensity. It is arranged with its north pole turned towards sclera at the place of the subretinal neovascular membrane projection with extrascleral arrangement of laser radiator lens membrane being provided in the subretinal neovascular membrane projection area. The other implant end is sutured to sclera 5-6 mm far from the limb via holes made in advance. The implant is covered with conjunctiva and retention sutures are placed thereon. Light guide and drug supply system lead is attached to temple with any known method applied. Drugs are supplied via the implant drug supply system in retrobulbary way in any order. Triombrast is given in the amount of 0,4-0,6 ml and dexamethasone or dexone in the amount of 0,4-0,6 ml during 3-4 days every 12 h. 0.1-1% aqueous solution of khlorin is intravenously introduced at the third-fourth day after setting the implant as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, at a bolus dose of 0.8-1.1 mg/kg. Visual control of subretinal neovascular membrane cells fluorescence is carried out by applying fluorescent diagnosis methods. After saturating the subretinal neovascular membrane with the photosensitizer to maximum saturation level, intravitreous, transretinal laser radiation of 661-666 nm large wavelength is applied at general dose of 30-120 J/cm2. The flexible polymer magnetolaser implant is removed and sutures are placed on conjunctiva. Permanent magnet of the flexible polymer magnetolaser implant is manufactured from samarium-cobalt, samarium-iron-nitrogen or neodymium-iron-boron system material. The photosensitizer is repeatedly intravenously introduced at the same dose in 2-3 days after the first laser radiation treatment. Visual intraocular neoplasm cells fluorescence control is carried out using fluorescent diagnosis techniques. Maximum level of saturation with the photosensitizer being achieved in the subretinal neovascular membrane via laser light guide and implant lens, repeated laser irradiation of the subretinal neovascular membrane is carried out with radiation dose of 30-60 J/cm2.

EFFECT: accelerated subretinal edema and hemorrhages resorption; regression and obliteration of the subretinal neovascular membrane; prolonged vision function stabilization.

6 cl

FIELD: medicine.

SUBSTANCE: method involves filling vitreous cavity with perfluororganic compound. Two electrodes manufactured from platinum group metal are intravitreally, transretinally introduced into intraocular neoplasm. Electrochemical destruction is carried out with current intensity of 10-100 mA during 1-10 min in changing electrodes polarity and their position in the intraocular neoplasm space, and the electrodes are removed. 0.1-1% aqueous solution of khlorin as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, is intravenously introduced at a dose of 0.8-1.1 mg/kg. Visual control of intraocular neoplasm cells fluorescence is carried out by applying fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, intravitreous, transretinal laser radiation of 661-666 nm large wavelength is applied at a dose of 30-120 J/cm2 in perfluororganic compound medium. The transformed retina and tumor destruction products are intravitreally removed with perfluororganic compound volume being compensated with its additional introduction. Boundary-making endolasercoagulation of retinotomy area is carried out. The perfluororganic compound is substituted with silicon oil. The operation is ended in placing sutures over sclerotmy areas and over conjunctiva. Perfluormetylcyclohexylperidin, perfluortributylamine or perfluorpolyester or like are used as the perfluororganic compound for filling vitreous cavity. Platinum, iridium or rhodium are used as the platinum group metals.

EFFECT: complete destruction of neoplasm; reduced dissemination risk.

6 cl, 12 dwg

FIELD: medicine, applicable for stopping of pains of various nature.

SUBSTANCE: the device has a quantum-mechanical oscillator located in a casing, magnet, vessel for medicinal agent and a hollow cylinder. The magnet is installed between the oscillator and the vessel. Positioned in the vessel is a hollow cylinder having through holes on its surface.

EFFECT: quick and absolute anestesia.

2 ex, 1 dwg

FIELD: medicine.

SUBSTANCE: method involves administering laser radiation therapy once a day using low intensity pulsating radiation of wavelength equal to 890nmand power density of 0.03 mW/cm2. Injured organ projection to frontal abdominal wall is exposed to radiation at the first laser therapy stage in two fields acting upon each field for 2 min with radiation pulse succession frequency equal to 80 Hz in applying stable contact-type method. Total treatment dose on two fields is equal to 0.008 J/cm2. The second laser therapy stage begins immediately after having finished the first one in applying radiation along the large intestine path using labile contact-type method in a way that radiation pulse succession frequency equal to 80 Hz is applied first during 1 min and then frequencies of 600, 150 and 300 Hz are applied also during 1 min, respectively. Total treatment dose is equal to 0.032 J/cm2 at the second stage. Total treatment dose is equal to 0.04 J/cm2 at both stages.

EFFECT: enhanced effectiveness in inhibiting dysbacteriosis; reduced frequency of postoperative complications.

Up!