Method of manufacturing device for demonstration of surgical accesses to posterior cranial fossa formations
SUBSTANCE: invention relates to medical models. Method includes visualisation of anatomic structures. For its realisation natural anatomical object is used, in which with latex mass, dyed to imitate blood colour, injection of artery and venous systems of brain vessel system is performed separately. Successively, skin flap, muscle-fascial structures and aponeurosis are moved apart above trepanation site. Mill hole of occipital and temporal bones is formed from which squama is resected. By means of semicircular cut is opened and drawn aside. Sections of cerebellum hemispheres substance are made detachable.
EFFECT: obtaining possibility to model close to real situation aimed at development of manual skills of neurosurgeons.
The invention relates to medicine, in particular to neurosurgery, normal and topographical anatomy, and can be used for training medical students and physicians surgical approaches for intracranial objects.
Known devices made of various materials, such as plastics, paper mache, or in the form of posters used in the learning process during the training of neurosurgeons. (The patent for useful model RU 45547. Published: 10.05.2005).
A disadvantage of the known devices is the inability of the simulation environment for the learner, close to real.
The purpose of the invention is to create a device that enables the development of the necessary manual skills neurosurgeons.
The objective is achieved by the fact that made the device for demonstration of surgical approaches to formation of the posterior cranial fossa by visualizing its anatomical structures, and as materials devices use natural anatomical object on which the latex by weight, dyed by the dye in the colour of blood, separately perform the injection of the arterial and venous systems vasculature, brain, consistently pushing the flap of skin, muscle and fascial structures and aponeurosis over the site trephination, form Presevo hole SATELEC is Oh and the temporal bones, from which resetinput scales, open semicircular cut and taken off to the side of the Dura, and the parts of the substance of the hemispheres of the cerebellum performs removable.
The method is implemented as follows.
As materials of the device use natural anatomical object on which the latex by weight, dyed by the dye in the colour of blood, separately perform the injection of the arterial and venous systems vasculature, brain, consistently pushing the flap of skin, muscle and fascial structures, the aponeurosis over the site trephination, form Presevo hole in the occipital and temporal bones from which resetinput scales, open semicircular cut and taken off to the side of the Dura, and the parts of the substance of the hemispheres of the cerebellum performs removable.
For training neurosurgeons practical skills of surgical interventions on the structures of the posterior cranial fossa is extremely important knowledge of anatomy and topography of this region. In particular, when retrosigmoid access to the structures of the posterior cranial fossa after skin incision, the aponeurosis is rendered scales occipital and temporal bones. Overlay prezioso holes and resection scales allow you to visualize the intracranial structures such as the hemisphere of the cerebellum, its vessels, the fourth geldose is. Further actions of the surgeon contribute to the inspection region of the cerebellopontine angle, internal auditory canal, etc.
Study and understand the techniques of the surgical approach, the assessment of its capabilities, the study of topographic-anatomic relationships of the structures of the posterior cranial fossa in the implementation of the relevant access is possible either with the direct presence at the time of surgical intervention in this area, either through natural anatomical preparation. The latter creates a real image of the surgical access with visualization of soft tissue structures, designated overlay prezioso holes, structures of the brain, blood vessels and cranial nerves.
We propose a device made by the method of polymeric embalming of natural anatomical object. Visualization of the structures of the posterior cranial fossa is achieved in stages. Pre-injection is performed latex by weight, dyed dye in the colour of blood, separate arterial and venous systems vasculature of the brain. A flap of skin, muscle and fascial structures, the aponeurosis over the site trephination apart. Formed Presevo hole, which is resection of the scale of the occipital and temporal bones in the required amount. Dura is opened by polyresinresin and aside. After discharge flap of Dura visualized intracranial structures of the posterior cranial fossa. If necessary, removed parts of the substance of the hemispheres of the cerebellum or the needle is injected to suboccipital lymphadenopathy puncture. The result is the demonstration of the place of formation of trepanation holes, structures of the posterior cranial fossa, open" when it is run, and their topographic-anatomical relationships.
A method of manufacturing a device for demonstrating surgical approaches to formation of the posterior cranial fossa, including its visualization of the anatomical structures, characterized in that use natural anatomical object on which the latex by weight, dyed by the dye in the colour of blood, separately perform the injection of the arterial and venous systems vasculature, brain, consistently pushing the flap of skin, muscle and fascial structures and aponeurosis over the site trephination, form Presevo hole in the occipital and temporal bones from which resetinput scales reveal poluokrugli cut and taken off to the side of the Dura, and the parts of the substance of the hemispheres of the cerebellum performs removable.
SUBSTANCE: invention relates to experimental medicine, namely to experimental gastroenterology and can be used for modelling autoimmune gastritis in rats. For this purpose water-salt antigen, containing mixture of homogenate of allogenic mucous membrane of stomach in physiological solution and complete Freund's adjuvant, with component ratio 1:4, is introduced to animal. Method ensures possibility of obtaining model on rats, what results in decrease of research work cost.
EFFECT: ensuring possibility of obtaining model on rats, what results in decrease of research work cost.
2 dwg, 6 cl
SUBSTANCE: invention relates to experimental medicine. Bioimpedancemetry (BIM) is carried out three times in the region of the apex of the heart at different points on an area of 5 mm2. The average value (Z avg.), and if the Z avg. is more than 220 Ohm, it speaks of the presence of anthracyclonic cardiomyopathy. The method is simple and makes it possible to reliably diagnose anthracyclonic cardiomyopathy in an experiment.
EFFECT: developing of a simple, objective method for diagnosing anthracyclonic cardiomyopathy in an experiment.
2 tbl, 1 ex
SUBSTANCE: invention relates to medicine, namely to experimental surgery and concerns prevention of post-resection hyperglycaemia after pancreatectomy in experiment. For this purpose 96 hours before pancreatectomy suspension containing twenty-four-hour culture of pancreatic island cells of newborn piglets in concentration 2×106 in 1 ml of medium is introduced into iliac region once.
EFFECT: method ensures complete insulin-independence of experimental animal after pancreatectomy due to selection of optimal number of introduced cells as well as time and place of their introduction.
SUBSTANCE: combination therapy for chronic limb ischemia is ensured by revascularisation osteomyoplasty performed on the laboratory animal with experimental limb on 7th day after modelling. It is followed with intraperitoneal introduction of L-arginine once a day assuring effective circulation management.
EFFECT: higher clinical effectiveness.
1 ex, 1 tbl
SUBSTANCE: invention refers to experimental medicine, particularly to experimental cardiopharmacology and can be used for endothelium dysfunction correction. For this purpose dysfunction is modelled by intraperitoneal introduction of L-nitro-arginine-methyl ester dosed 25 mg/kg daily during 7 days to rats. This therapy is combined with endogastric introduction of macrolide agent Josamycin dosed 10 and 30 mg/kg singly a day.
EFFECT: method provides correction in any antioxidant profile.
1 ex, 1 tbl
SUBSTANCE: invention concerns medicine and medical equipment namely bracing of a knee joint of laboratory rabbits. The method of calculation of the individual form of an internal circle of a pressing pelot on a knee joint of laboratory rabbits consists that on the roentgenogram of a knee joint executed in a direct projection, the whirlbone is divided in lines of 12 equal to 30 degrees of angles. Construction of the form of the pressing pelot is spent on points of crossing of beams with a whirlbone circle, having receded on two millimetres from it.
EFFECT: calculation of the form of internal circle of pressing pelot on knee joint of laboratory rabbits.
SUBSTANCE: invention concerns experimental medicine, namely to experimental rheumatology and can be used for pseudorheumatism modelling. For this purpose 4 mg of an ovalbumin into 1 ml of full Freund's adjuvant (FFA) in the knee joint area are entered subcutaneously. After ovalbumin introduction in FFA, intravenously a papain in a dose of mass of a body of 8-10 mg/kg is entered. Then for 12 days from the beginning of formation of model 5 mg of an ovalbumin is entered into a cavity of a knee joint, thus enter an ovalbumin in FFA unitary.
EFFECT: reduction of quantity of stages and terms of modelling of pseudorheumatism, formation of more expressed system inflammatory reactions in an organism that allows to spend approbation of complex ways of treatment with use not only locally - but also is system operating preparations.
SUBSTANCE: invention concerns area of experimental medicine and can be applicable for modelling of treatment of full-layer defects of a cartilage of a knee joint. Walls and the bottom of the defect are modelled. An intake of a tissue fragment of a fatty body is made for the subsequent allocation and cultivation of the autolofous mesenchymal stem cells. The cultivated cells are injected paracentetic three times in a cavity of the knee joint.
EFFECT: maintenance of advance of is degenerate-dystrophic changes, regenerate formation optimisation in the field of defect.
1 ex, 4 dwg
SUBSTANCE: invention concerns experimental medicine and can be used for modelling of an immunodeficiency, characteristic for oncologic patients. For what the compelled swimming of animals in water is carried out at temperature 18°-20°C for 15-20 minutes - within 3 days daily. Then next day a single intraperitoneal injection of Cyclophosphanum of 8-10 mg is spent counting on 100 g weight of a body of an animal to 1.0 ml of a solution and research of immunologic indicators for 5-6 day after an injection.
EFFECT: provision of adequate reproduction of model by the most approached to a real situation at the expense of preliminary stress activation.
1 tbl, 4 ex
FIELD: medicine; dentistry.
SUBSTANCE: phantom includes upper and lower jaw imitations with segments with rigid basis, fundament and alveolar bones, extracted natural teeth with roots fixated in basis, artificial elastomer gum, elements for segment fixation to imitations. External side of rigid basis carries at least one slot of depth sufficient for tooth root top denudation by 2-3 mm of height and length sufficient to provide access to roots of at least two teeth. The slot is closely covered by removable element made of elastoplastic material, so that indicated root tops are embedded into the element body, and external surface of removable element mirrors internal surface of artificial gum.
EFFECT: phantom allows performing manipulations of tooth removal, mucosa incision and post-operational stitching, inflammation focus removal and all standard manipulations of orthopedic and therapeutic dentistry.
6 cl, 5 dwg
FIELD: medicine, experimental abdominal surgery.
SUBSTANCE: as experimental animals one should apply mongrel dogs of 12-17 kg body weight. Under general anesthesia one should conduct superior-median laparotomy, introduce 3.0 ml 70%-ethanol solution under pancreatic capsule and then laparotomic wound should be sutured up. Manipulation should be performed once. The method provides modeling adequate acute pancreatic inflammation at no side effects being very simple in implementation.
EFFECT: higher efficiency.
FIELD: medicine; medical engineering.
SUBSTANCE: method involves studying transverse longitudinal and rotation stiffness characteristics. The studies are carried out step-by-step from the first order units to complete external fixation apparatus structure. The device has frame and is provided with calibration loads, wire rope, displacement indicators, strip for fastening to loading end of bone imitator fragment, beam for fixing displacement indicators, beams having unit for modeling longitudinal and transverse loadings. The frame is manufactured as parallelepiped. The fixing panel has openings for bone imitator, for fixing external fixation apparatus and yoke connection union and is fixed in end face part of the frame. Beam for fixing displacement indicators has longitudinal slit for fixing the indicators and arranging them on lateral slots in frame base. The beams having unit for modeling rotational, longitudinal and transverse loadings are arranged on lateral frame sides on lateral slots in base.
EFFECT: high vision acuity without applying spectacle-based correction; accelerated treatment course.
2 cl, 16 dwg, 1 tbl
FIELD: experimental medicine.
SUBSTANCE: the present innovation deals with modeling urinary calculosis in rats due to injecting intraperitoneally 60%-glucose solution at 1 ml/100 g animal body weight twice daily for 2 mo. The method is very simple and enables to achieve lithogenesis in 25% experimental animals.
EFFECT: higher efficiency of experimental modeling.
2 dwg, 2 ex, 4 tbl
SUBSTANCE: method involves using Hann diode crystal with proper frequencies of pathogenic microorganisms and cells during their death period or during the stimulating factors action period being applied.
EFFECT: enhanced effectiveness of treatment; wider range of biophysical action types.
3 cl, 1 tbl
FIELD: medicine, experimental physiology.
SUBSTANCE: hypoxia with hypercapnia should be modeled due to creating a closed system of inhaled air circulation. Air enters lungs out of hermetically sealed reservoir and at expiration returns back. The process of recirculation is supplied with an apparatus of artificial pulmonary ventilation. The innovation suggested provides steadiness in development of hypoxia with hypercapnia excluding the development of stressor reaction. Conditions should be created to carry out any manipulations with an animal in the course of an experiment.
EFFECT: higher efficiency of modeling.
5 dwg, 1 ex
FIELD: medicine, stomatology.
SUBSTANCE: the present innovation should be carried out for the purpose to study ethiology and pathogenesis of parodontitis. One should affect with emotional stress in experimental animals (mature rats) due to placing 10-11 experimental animals into the cage at area of 0.018 sq. cm/animal. Before placing into the cage one should create artificial dental plaque around the cervix of the upper and lower incisors with the help of stomatological cement for every experimental animal. In the course of modeling all experimental animals should eat paste-like food. The method enables to shorten terms for obtaining the model desired and increase its similarity with pathomorphological manifestations of human parodontitis.
EFFECT: higher efficiency of investigation.
FIELD: medical equipment.
SUBSTANCE: device has input first variable resistor, capacitor and permanent resistor. Permanent resistor is connected to arm second and third variable resistors. Second ends of variable resistors are connected with motionless contacts of polarized relay. Movable contact of relay is connected to common bus. Input of device is connected to amplifier which has output connected with control wiring of polarized relay. Second end of wiring is connected with common bus. Device is intended for electrical modeling of balanced and misbalanced conditions of acupuncture point at electropunctural action with unlike-poled signals due to liquidation mutual errors at any circuit of opposite arms of the device. Values of active resistances can be installed independently at any arm of device.
EFFECT: increased precision.
FIELD: experimental medicine.
SUBSTANCE: laboratory animals should be once injected intraperitoneally or intravenously with phenylhydrazine at the dosage of 100-150 mg/kg.
EFFECT: higher efficiency.
1 cl, 4 ex, 2 tbl
FIELD: medicine, experimental biology, ecology, toxicology.
SUBSTANCE: at studying the mechanisms of heavy metals toxic action, in particular, cadmium upon renal function, it is suggested to introduce cadmium sulfate solution into stomach once daily for 2 mo at the dosage of 0.5 mg/kg, on conversion to metal, where cadmium corresponds to 0.5 mg per 1 ml solution. The present innovation enables to study the pathology in dynamics of development and elaborate and searching preparations for treating and preventing chronic toxic nephropathy.
EFFECT: higher efficiency.
1 ex, 3 tbl
SUBSTANCE: method involves exposing cell or cell group to external power source. At least two electrodes are introduced before treating the cells. One of electrodes is set on cytoplasmatic external cell membrane surface and the other one cell membrane and membrane potential value is measured. External electric voltage source is connected to the introduced electrodes oppositely in polarity with cell membrane potential difference value being not less than cell membrane potential.
EFFECT: enhanced effectiveness in building cell damage model by means of energy burst and death.