Method of synchronous registration of rheogram from ecg electrodes and device for its realisation

FIELD: medicine.

SUBSTANCE: electrodes of electric ECG potential registration are placed in zone of aorta and in zone of cardiac apex. Changes of electric potential on body in time are registered in form of diagram of ECG function. Near each electrode of ECG electric potential registration additional electrode is installed, onto which high-frequency signal from generator is supplied, and from electrodes of ECG electric potential registration modulated by fluctuations of arterial blood flow signal is obtained synchronously, said signal is amplified, converted into digital code and transmitted for rheogram registration to information processing unit, after which connection of ECG electric potential with change of pressure according to rheogram is connected in each phase, and phase peculiarities of arterial pressure change are diagnosed. Device for synchronous registration of rheogram from ECG electrodes consists of two ECG electrodes, commutator, first amplifier, first band filter, analogue-digital converter, controller, IR transmitter and information processing unit with first detector, commutator being inserted between electrodes and first amplifier, whose outlet through band filter is connected with first inlet of analogue-digital converter, whose outlet is joined to controller, whose first outlet is connected with commutator, and second outlet - with IR transmitter, connected with first detector of information processing unit. Two additional electrodes, second amplifier, second band filter, second detector and generator, switched to additional electrodes, are introduced into it, second commutator outlet is connected to inlet of second detector, whose output through second amplifier and second band filter is connected with second inlet of analogue-digital converter.

EFFECT: synchronous registration of phase characteristics of cardiac cycle and corresponding fluctuations of arterial pressure in heart vessels and aorta.

2 cl, 3 dwg

 

The present invention relates to medicine, namely to measurements for diagnostic purposes in cardiography, and can be used in cardiology for the diagnosis of the functional state of the heart and blood vessels.

There is a method of measuring the duration of the phases of the cardiac cycle (journal of Cardiology, Keizer IM "Differential curves carotid and regular heart rate in healthy and some vices", 1968, No. 5, p.81).

The known method is that in the region of the heart set the electrodes on the standard derivations from I to VI and three sensors. One of the sensors registers ECG and installed in one of the standard branches. The second sensor is an acoustic registers of the sound wave propagating from the working of the heart valves, and installed in the area of the aorta. The third sensor is installed in the area of the carotid artery and registers the mechanical vibrations of the carotid artery caused by the movement of blood flow. The signals from the three sensors register and receive three graphs: ECG, phonocardiogram (FCG) and sphygmogram carotid artery (SFG). At the beginning of the emergence of sound waves on phonocardiogram and end define the duration of the phases of the cardiac cycle of the ECG.

Signs of similar, coinciding with the essential features of the proposed method are the sensors (in savla the IOM method, the ECG electrodes) and their location in the heart with simultaneous recording of the ECG.

A reason to obtain a technical result, is the lack of use for this induction sensors metrological security.

There is a method of measuring the duration of the phases of the cardiac cycle and the device for its implementation (RF patent No. 9409237, And 61 In 5/02). The known method is that place the electrode in the heart and perform simultaneous registration of ECG, FCG and SFG radial artery, and then on mathematical dependences carried out the calculation of the second derivative of SFG radiation (carotid) artery and build the graph of F(x) no d(t). Further, according to the characteristic points on the graph of the second derivative with regard to the reference ECG curves and FCG carry out the calculation of the duration of the phases of the cardiac cycle.

Signs of similar, coinciding with the essential features of the proposed method are the electrodes (in the present method, the ECG electrodes) and their location in the region of the heart, as well as simultaneous ECG registration.

A reason to obtain a technical result, is a long time to prepare the sensors for their simultaneous operation, as they register the signals of different nature, which significantly complicates the measurement.

Closest to the claimed method is a method of measuring the duration of the phases of the cardiac cycle and device for its implementation the program (the floor. solution 30.03.2006, application No. 2004132980 from 11.11.2004 g), namely, that in the method of measuring the phases of the cardiac cycle, including the placement of electrodes in the heart and the registration of change of electric potential of a body in time in the form of a graph, one electrode is placed in the area of the aorta, and the other in the zone of the apex of the heart, the graph of the function (ECG) F(x) defines the characteristic point AR, R, M, and Z-register the first derivative of the resulting function ECG, the graph of F(x) determine the characteristic inflection point F, AR, P, Q, R, M, S, Z, T, U, h, intervals between which determine the duration of all phases of the cardiac cycle: phases of the opening of the semilunar valves in the interval M-Z, phase asynchronous contraction of the myocardium in the interval Q-R, phase of isometric contraction of the myocardium on the interval R-S phases of fast and slow expulsion of blood, respectively, in the intervals of S-T and T-U, phase protodiastolic on the interval U-R, phase isometric relaxation of the myocardium on the interval h-AF phases of fast and slow filling of the Atria accordingly, interval AF-F and F-AR phase of systole of Atria on the interval AR-Q, then compare the duration of phases with durations of phases, representing the physiological norm, and identify the deviation in % from the physiological norm.

The characteristics of the prototype, coinciding with significant attribute is the kami of the proposed method, are the electrodes (in the present method, the ECG electrodes) and their location in the zone of the aorta and in the zone of the apex of the heart, as well as registration of changes in the electrical potential on the body over time in the form of a graph function ECG.

The reason the technical result is the impossibility of simultaneously recording the phase characteristic of the cardiac cycle and the corresponding fluctuations in blood pressure in the vessels of the heart and aorta.

The task, which is aimed by the invention is the simultaneous registration of the phase characteristics of the cardiac cycle and the corresponding fluctuations in blood pressure in the ascending aorta.

The technical result is achieved by the fact that beside each electrode recording electrical potential ECG establish an additional electrode, which includes a high-frequency signal generator, and electrodes detect electrical potential ECG synchronously receive the modulated oscillations of blood pressure of the blood flow signal, which commute, highlight, enhance, convert into digital code and transmit to register rogramme in the processing unit, and then compared to each phase connection of the electrical potential of the ECG with the pressure change in rogramme and diagnose phase special the spine changes in blood pressure.

To achieve a technical result, in the method of measuring the phases of the cardiac cycle, including the location of the electrodes detect electrical potential of the ECG in the area of the aorta and in the zone of the apex of the heart, recording changes in the electrical potential on the body over time in the form of a graph function, ECG, next to each electrode recording electrical potential ECG install additional electrode, which serves high-frequency signal generator, and electrodes detect electrical potential ECG synchronously receive the modulated oscillations of blood pressure of the blood flow signal, which commute, highlight, enhance, convert into digital code and transmit to register rogramme in the processing unit, then compare to each phase connection of the electrical potential of the ECG with the pressure change in rogramme diagnose and phase characteristics of the changes in blood pressure.

A device that implements the method of obtaining the electrocardiogram and device for its implementation (patent RF №2063167, AV 5/0402), consisting of electrodes, connected to the input of cardiology, which contains the amplifiers and the switch of biopotentials, cardiolog connected to the first input of analog-to-digital Converter (ADC)connected to the computer via the unit will precede the through-processing.

Signs of similar, coinciding with the essential features of the claimed device, are the electrodes (in the inventive device, the ECG electrodes), amplifier, switch, ADC, PC (in the inventive device, the processing unit).

The reason the technical result is the complexity and duration of the procedure for removing the ECG in time.

A device that implements a method of creating a biological feedback for correction of cardiac activity and device for its implementation (patent RF №2118117, AB 5/04)containing the electrodes, amplifier, switch, ADC, encoder, IR transmitter and at the receiver side, the decoding device and the computer.

Signs of similar, coinciding with the essential features of the claimed device, are the electrodes (in the inventive device, the ECG electrodes), amplifier, switch, ADC, transmitter (in the inventive device IR transmitter), computers (in the inventive device, the processing unit).

The reason the technical result is the impossibility of registering oscillations of blood pressure in the ascending aorta due to the lack of software.

Closest to the proposed device is a device for the application "Method for measuring the duration of the phases of the cardiac cycle and the device for the th implementation" (the floor. solution 30.03.2006, application No. 2004132980 from 11.11.2004,) consisting of two electrodes, an amplifier, a switch, ADC, IR transmitter and processing unit, and a switch connected between the electrodes and the amplifier, the amplifier output through a band-pass filter is connected to the ADC, the output of which is connected to the controller, the first output of which is connected to the switch, and the second output to the infrared transmitter, the processing performed on the series connected detector, the interface, the processor and the display.

The characteristics of the prototype, coinciding with the essential features of the claimed device, are the electrodes (in the inventive device, the ECG electrodes), switch, amplifier, bandpass filter, ADC, controller, IR transmitter, the processing unit information.

The reason the technical result is the impossibility of registering oscillations of blood pressure in the ascending aorta.

The task, which is aimed by the invention is the simultaneous registration of the phase characteristics of the cardiac cycle and the corresponding fluctuations in blood pressure in the vessels of the heart and the aorta.

The technical result is achieved by the fact that in the known device entered the second amplifier, the second band-pass filter, a second detector, the generator, the signal from which is fed to two additional electrode, and the second output switch connected to the second detector, the output of which through the second amplifier and the second bandpass filter connected to the second ADC input.

To achieve a technical result in a device consisting of two electrodes, switch, amplifier, bandpass filter, ADC, controller, IR transmitter and processing unit, and a switch connected between the electrodes and the amplifier, the amplifier output through a band-pass filter is connected to the ADC, the output of which is connected to the controller, the first output of which is connected to the switch, and the second output to the infrared transmitter, entered the second amplifier, the second band-pass filter, a second detector, the generator, the signal of which is fed to two additional electrode, and the second output switch connected to the second detector, the output of which through the second amplifier and the second bandpass filter connected to the second ADC input.

Description of the claimed invention clarify the drawings, in which figure 1 shows the location of the electrodes on the body, figure 2 presents simultaneous ECG recording and rogramme, figure 3 shows the block diagram of a device implementing the method of the synchronous registration rogramme from the ECG electrodes.

Figure 1 positions 1, 2 - ECG electrodes (the electrodes, the electrical potential of the body in time), 3, 4 - additional electrodes.

On Phi is .2 upper curve represents the recorded ECG, the lower curve registered rogramme, which is a function of changes in the magnitude of the conductivity of blood in the area between the electrodes, which corresponds to the oscillations of blood pressure. The appropriate phase of the cardiac cycle on the ECG graph will correspond to the blood pressure chart rogramme.

Figure 3 shows the block diagram of a device that implements the inventive method, where Al and Al - ECG electrodes El and El - additional electrodes, 1 - switch, 2 - power, 3 - band-pass filter, 4 - d, 5 - controller, 6 - IR transmitter 7 to the processing unit. The ECG electrodes El and El connected to the first input of the switch 1, the first output of which is connected to the amplifier 2, the output of which is serially connected through a band-pass filter 3 to the first input of the ADC 4, the output of which is connected to the input of the controller 5, the first output of which is connected to a second input of switch 1, and a second output connected to the input of the IR transmitter 6, which signal is then fed into the processing unit 7. Additional electrodes El and El connected to the generator 8. The second output of the switch 1 through the second detector 9, the second amplifier 10, a second band-pass filter 11 is connected to a second input ADC 4.

Consider the work of the proposed method: the ECG electrodes El and El mounted on the body of the patient, in one area of the aorta, on the natives in the area of the apex of the heart (figure 1). Next install additional electrodes El and El, which serves high-frequency signal generator 8. From the ECG electrodes El and Al simultaneously record two signals: one signal ECG, other modulated oscillations of blood pressure, blood flow, i.e. the signal rogramme. These signals are sent to the switch 1. The signal rogramme is influenced by the modulation of high-frequency generator 8 low-frequency fluctuations in the blood. From the outputs of the switch 1 these signals are divided: a signal corresponding ECG, through the amplifier 2 and the band-pass filter 3 is supplied to the first input of the ADC 4, and a signal corresponding reogramme, allocate the second detector 9 through the second amplifier 10 and the second band-pass filter 11 is passed to the second input of the ADC 4. Both signal through the controller 5, the IR transmitter 6 are received at the processing unit 7, the output of which is synchronously recorded graphics ECG (figure 2, upper graph), and rogramme (figure 2, lower graph). Thus, the recorded rogramme is a function of changes in the magnitude of the conductivity of blood in the area between the electrodes, which corresponds to the fluctuations in blood pressure.

Consider a device that implements the inventive method. On the patient's body are strengthened ECG electrodes El and El. Next to them are the extra e is ctrode S and Al. High-frequency signal generator 8 is supplied to the additional electrodes El and El. On the ECG electrodes El and Al occur simultaneously two signals: ECG signal and the signal modulated by the oscillations of blood pressure, i.e. the signal rogramme that arrives at the switch 1. The first output switch 1 recorded ECG signal is supplied to the amplifier 2, then through the bandpass filter 3 on the first ADC input 4, which converts the analog signal into a corresponding digital code. The signal rogramme also removed from the ECG electrodes El and El and to the input of the switch 1. From the second output switch 1 signal rogramme is fed to the additional detector 9, which allocates the modulating low frequency signal characterizing the fluctuations of arterial blood pressure. With the additional output of the detector 9 signal rogramme comes through consistently connected to the second amplifier 10 and the second band-pass filter 11 to the second input of the ADC 4. ADC output 4 synchronous ECG signal and the signal rogramme enter the controller 5 and later in IR transmitter 6, which are received in the processing unit 7, the output of which is synchronously recorded graphics ECG and rogramme. To check the efficiency of the device can be fed to the second amplifier 10, the test signal, then the generator 8, the signal is sent on to mutator 1.

The proposed method and device for its implementation provide raising awareness of the prototype due to the simultaneous reception of two signals in one area of the body, namely the electric potential of the ECG and the reaction vessel at his irritation, eliminating phase of their differences if they are registered in more than one area on the body, but in different zones. Synchronously recorded with the same electrode ECG electrocardiogram and rogramme more detailed and informative reflect the processes in each phase of the cardiac cycle.

Given that the prototype calculates the phase of the cardiac cycle with high accuracy, using only ECG, you can use synchronous recording rogramme to evaluate the mechanical response of the heart muscle and blood vessels on setting the rhythm of electrocardiograma.

Diagnostic value of the method lies in the fact that under normal propagation of an electrical signal along the nerves to the muscle contraction may be pathological because of thrombi in the microvasculature or swelling of the cell walls of muscle. The proposed phase analysis allows us to estimate for each phase state of the blood pressure and to identify what the source of pathology in the General integral picture of the functioning of the heart and blood vessels.

1. Way simultaneous registration rogramme with ECG electrodes, including the location of the electrodes registration e is aktionscode potential ECG in the area of the aorta and in the zone of the apex of the heart, registration of changes in the electrical potential on the body over time in the form of a graph function, ECG, characterized in that beside each electrode recording electrical potential ECG install additional electrode, which serves high-frequency signal generator, and electrodes detect electrical potential ECG synchronously receive the modulated oscillations of blood pressure of the blood flow signal, which commute, highlight, enhance, convert into digital code and transmit to register rogramme in the processing unit, and then compared to each phase connection of the electrical potential of the ECG with the pressure change in rogramme diagnose and phase characteristics of the changes in blood pressure.

2. Device for simultaneous registration of rogramme with ECG electrodes, consisting of two ECG electrodes, the switch of the first amplifier, the first bandpass filter, an analog-to-digital Converter, controller, IR transmitter and processing unit with the first detector, and a switch connected between the electrodes and the first amplifier, the output of which through the band-pass filter connected to the first input of analog-to-digital Converter, the output of which is connected to the controller, the first output of which is connected to the switch, and the second output from the To the transmitter, associated with the first detector processing unit, characterized in that it introduced two additional electrode, a second amplifier, the second band-pass filter, a second detector and generator connected to the secondary electrode, the second output switch connected to the input of the second detector, the output of which through the second amplifier and the second bandpass filter connected to the second input of the analog-to-digital Converter.



 

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FIELD: medicine; obstetrics.

SUBSTANCE: fetal cardiac rhythm is registered. Additionally cardiointervalography is performed with determination of spectral power density of maternal and fetal cardiac rhythm waves and selection of very low frequency VLF, low frequency LF and high frequency HF levels, regulator system tension index TI, cortizol and adrenaline level in maternal and fetal blood. Physiological pregnancy course is defined at adrenaline level of 28 ng/mol, cortizol level of 360 ng/ml, indices of VLF=120 relative units, LF=40 r.u., HF=20 r.u., TI=70 r.u., for the mother and at indices of VLF=25 r.u., LF=2 r.u., HF=1 r.u., TI=250 r.u. for the fetus; compensated form of chronic fetoplacental deficiency is detected at the adrenaline level of 46 ng/ml, cortizol level of 695 ng/ml, VLF=180 r.u., LF=50 r.u., HF=100 r.u., TI=160 r.u. for the mother and at VLF=45 r.u., LF=5 r.u., HF=1 r.u., TI=400 r.u. for the fetus; and decompensated form of chronic fetoplacental deficiency is detected at the adrenaline level of 2 ng/ml, cortizol level of 1003 ng/ml, VLF=900 r.u., LF=25 r.u., HF=10 r.u., TI=30 r.u. for the mother and at VLF=3 r.u., LF=1 r.u., HF=0 r.u., TI=700 r.u. for the fetus.

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EFFECT: improved accuracy and information capacity of diagnostics of physiological pregnancy course and chronic fetoplacental deficiency forms.

1 dwg, 9 tbl

FIELD: medicine.

SUBSTANCE: electrodes of electric ECG potential registration are placed in zone of aorta and in zone of cardiac apex. Changes of electric potential on body in time are registered in form of diagram of ECG function. Near each electrode of ECG electric potential registration additional electrode is installed, onto which high-frequency signal from generator is supplied, and from electrodes of ECG electric potential registration modulated by fluctuations of arterial blood flow signal is obtained synchronously, said signal is amplified, converted into digital code and transmitted for rheogram registration to information processing unit, after which connection of ECG electric potential with change of pressure according to rheogram is connected in each phase, and phase peculiarities of arterial pressure change are diagnosed. Device for synchronous registration of rheogram from ECG electrodes consists of two ECG electrodes, commutator, first amplifier, first band filter, analogue-digital converter, controller, IR transmitter and information processing unit with first detector, commutator being inserted between electrodes and first amplifier, whose outlet through band filter is connected with first inlet of analogue-digital converter, whose outlet is joined to controller, whose first outlet is connected with commutator, and second outlet - with IR transmitter, connected with first detector of information processing unit. Two additional electrodes, second amplifier, second band filter, second detector and generator, switched to additional electrodes, are introduced into it, second commutator outlet is connected to inlet of second detector, whose output through second amplifier and second band filter is connected with second inlet of analogue-digital converter.

EFFECT: synchronous registration of phase characteristics of cardiac cycle and corresponding fluctuations of arterial pressure in heart vessels and aorta.

2 cl, 3 dwg

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to devices of medico-biological purpose, intended for registration and evaluation of fast-proceeding physiological reactions, emerging as response to produced stimuli. Device contains microcontroller, analogue-digital converter (ADC), first commutator, sensors of breast breathing, abdominal breathing, skin-galvanic response, arterial pressure, cardio-vascular activity, sensor of motor activity, power unit, preliminary amplifiers, signal amplifiers, filters, first and second digital-analogue converters (DAC), tool amplifier and unit of connection with personal computer, supplied with galvanic attenuator. Via amplifiers and filters sensors are connected with corresponding inputs of commutator whose controlling input is connected with first microcontroller bus, and output - with first input of tool amplifier. Second input of tool amplifier is connected to output of first DAC, third input - to output of second DAC, and output - to ADC input. Inputs of first and second DAC and group of inputs-outputs of ADC are connected with second microcontroller bus, whose third bus is connected to unit of connection with personal computer. Additional channel has possibility of connection to its input of face mimics sensor, piezoplethysmogram or variable component of skin-galvanic response and includes second electronic commutator, to whose outputs subchannels of processing of signals from corresponding sensor are connected. First subchannel includes successively connected preliminary amplifier and filter, second subchannel - preliminary amplifier, filter, signal amplifier and additional filter, and outputs of subchannels via third electronic commutator are connected to first commutator input. Controlling input of third commutator is connected with microcontroller.

EFFECT: registration of maximal number of physiological parametres and ensuring objectivity of obtained information.

2 cl, 2 dwg

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