Method of complex treatment of acute enteric infections

FIELD: medicine.

SUBSTANCE: antibacterial and rehydration therapies are combined with prescribed sorbents, symptomatic therapy. From first day of disease prescribed is infusion herb collection consisting of silverweed rhizome, salvia leaves, milfoil herb, St. John's wort herb, inula rhizomes with roots, tickseed herbs, mint leaves, fennel fruits and buckthorn bark at ratio of components 2:2:2:2:2:2:2:2:1. Infusion is taken up dosed 1\3 glass 3 times a day, 30 min before meal within 10 days. Then within three weeks after basic therapy appoint infusion from silverweed rhizome, salvia leaves, milfoil herb.

EFFECT: provides accelerated normalisation of clinical-laboratory indicators, and prevention of infectious complications without by-effects.

2 cl, 1 tbl, 1 ex

 

The present invention relates to medicine, namely, gastroenterology, and can be used for the integrated treatment of acute intestinal infections and prevention of complications.

Among infectious diseases is a significant component of acute intestinal infections, which often are caused by pathogenic strains of E. coli, Staphylococcus, dysenteric bacteria, Salmonella, etc. also cause acute lesions of the intestine become such representatives of conditionally pathogenic flora, as Klebsiella, Citrobacter, Proteus, etc. After acute intestinal infections occur transient or persistent changes of the intestinal microbial flora and the clinical picture of patients have different symptoms: flatulence, flatulence, intolerance to specific foods, vitamin deficiencies, skin rash. Changes of microbial flora is characterized by the appearance in the intestine in an uncharacteristic of microorganisms while reducing the representatives of the indigenous flora [Suprunov A.M., cottage of wattle LN. Microbial flora of the gut and probiotics (B-ka practical use. doctor) // Actual problems of modern medicine. - M., 2001. - P.17-18].

The basis of treatment of acute intestinal infections is a complex therapy, including antibacterial drugs (antibiotics, sulfonamides, produced by the water 8-oksihinolina biological products), detoxication therapy (antidotes), the effect on related processes that occur in the course of the disease and its treatment (enzymes, vitamins, adaptogens). However, synthetic drugs often cause side effects (allergic, toxic), breach of normal intestinal biocenosis, lower immunity. Herbal medicine is a promising method in treatment of acute intestinal infection, its complications and related processes.

The closest analogue of the present invention to the technical essence and the achieved result is a method of treatment of patients after acute intestinal infection, using a collection of the following composition: rhizomes and roots of Burnet (or rhizomes cinquefoil; or stems alder) 35%; plantain leaves 20%; yarrow herb 15%; leaves mother and stepmother 15%; the sage leaves 15% [Ermakova, VA pharmacognostically study and standardization of fees, briquettes, vegetable powders / Thesis. on competition of a scientific degree of the doctor of Pharm. Sciences. - M., 1999. - P.70-71].

The above method has some drawbacks, as the plant collection is assigned to patients who have suffered acute intestinal infections to restore normal biocenosis and functions of the intestine. However, phytotherapy, you must assign paralleles comprehensive therapy to reduce the side effects of synthetic drugs and as maintenance therapy after primary treatment.

The technical result - increase of efficiency of treatment of acute intestinal infections due to shortening and prevention of complications.

This technical result is achieved in that in the method, including basic therapy with the use of antibiotics, rehydration therapy, sorbents, symptomatic therapy, the tincture of the collection of medicinal plants containing rhizome tormentil, sage leaves, yarrow herb within 3 weeks after basic treatment, from the first day of the disease within 10 days of basic therapy prescribed fee, which additionally contains the herb, rhizome with the roots of Valerian, an herb, peppermint leaf, fennel fruit and the bark of buckthorn in a ratio of components in parts 2:2:2:2:2:2:2:2:1 accordingly, 1/3 Cup 3 times a day, 30 minutes before meals, at the same time as antibiotic therapy administered antibiotics - Amazin 400 mg/day, sulfonamides - the appointment of 2.0-4.0 g/day for 7 days, as rehydration therapy - saline, Trisol/drip in the amount of 1200-800 ml per day for 5 days, then regidron per os to 1 l per day for 5 days, as sorbents - POLYSORB for 1.0-2.0 g of the powder in suspension 3 times a day for 10 days, and as symptomatic therapy antispasmodics - no-Spa first 2-3 DN is/m 2% solution 3 times a day, then per os at 0.18 g/day for 7 days and antipyretics - 50% solution of dipyrone and 1% solution Dimedrol 2 times a day for 2-3 days.

The proposed method is as follows: conduct basic therapy, which includes the appointment of antibacterial agents, namely antibiotics - Amazin 400 mg/day, sulfonamides - the appointment of 2.0-4.0 g/day for 7 days, rehydration therapy, namely saline, Trisol/drip in the amount of 1200-800 ml per day for 5 days, then regidron per os to 1 l per day for 5 days, sorbents - POLYSORB of 1.0-2.0 g of the powder in suspension 3 times a day for 10 days, symptomatic therapy, namely antispasmodics - no-Spa for the first 2-3 days/m 2% solution 3 times a day, then per os at 0.18 g/day for 7 days, fever is a 50% solution of dipyrone and 1% solution Dimedrol 2 times a day for 2-3 days. From the first day from the beginning of the disease the patient is prescribed an infusion of medicinal plants containing rhizome tormentil, sage leaves, yarrow herb, herb, rhizome with the roots of Valerian, an herb, peppermint leaf, fennel fruit and the bark of buckthorn in a ratio of components in parts 2:2:2:2:2:2:2:2:1 accordingly, 1/3 Cup 3 times a day, 30 minutes before meals for 10 days. To prevent complications of acute intestinal infections nasties collect appoint additional within 3 weeks after basic treatment. The aqueous extract is prepared in a ratio of 1:10, in a boiling water bath mode 15 min heating and 45 minutes cooling at room temperature, filter, add water to the desired volume [of the State Pharmacopoeia of the USSR: 2). General methods of analysis. Medicinal plant raw materials. - 11th ed., extra - M.: Medicine, 1989. - S-148].

The proposed method treated 72 patients. We observed two groups of patients. The first group of 30 people: men - 18 (60%), women - 12 people (40%). The average age from 14 to 47 years. The second group (control) - 42 people aged from 14 to 53 years of age, was treated without the use of the collection.

Clinical symptoms of acute intestinal infections included: obstipation (fever, symptoms of intoxication), diarrhea, dyspepsia (nausea, vomiting, abdominal pain, loss of appetite) syndromes.

The research results presented in the table show that the first group who received integrated treatment using drugs main course and herbal, indicators exceeded the results of the second group using only the baseline treatment (table). In the first group, a positive dynamics was observed on the third day of treatment and was characterized by complete recovery of patients on day 7; the second group of patients positive dynamics was observed mn is considerably later.

Example 1: the Patient And, in 1969, was admitted to the hospital with complaints of temperature rise up to 38°C, liquid stool up to 10 times a day, nausea, pain, spastic nature in the abdomen, severe weakness. Pain in acute per day before admission.

Blood count: leukocytes 8,7·109/l, erythrocytes-3,8·1012/l, hemoglobin 113 g/l, erythrocyte sedimentation rate of 23 mm/h

Fecal: total number of coliform bacilli 56 m/g, coccal forms in a total sum of 100% St.haemolyticus, Enterococcus, 105the fungi of the genus Candida 100% C.albicans, bifidobacteria is not detected, lactobacilli is not detected, lactic acid streptococci 107.

Treatment was conducted: Amazin 400 mg/day, the appointment of 4.0-6.0 g/day for 7 days, rehydration therapy (in/in, per os): saline, Trisol/drip in the amount of 1200-800 ml per day for 5 days, then regidron per os to 1 l per day for 5 days, POLYSORB 3-6 grams of powder per day for 10 days, no-Spa for the first 2-3 days/m 2% solution 3 times a day, then per os at 0.18 g/day for 7 days, 50% solution of dipyrone and 1% solution Dimedrol 2 times a day for 2-3 days. Treatment added infusion of the proposed collection 1/3 Cup 3 times a day, 30 minutes before meals for 10 days on the sidelines of the main treatment and prevention of complications of acute intestinal infections independently infusion of collection within 3 weeks.

After 2 days nablyudatelnostyu state, which was manifested by the decrease of temperature, improvement of General condition, after 3 days the disappearance of nausea, appetite improved; the normalization of bowel movement in 5 days.

After 7 days in the blood: leukocytes 6,5·109/l, erythrocytes 5,0·1012/l, hemoglobin 122 g/l, erythrocyte sedimentation rate of 14 mm/h

Analysis of feces for 7 day treatment: the total number of coliform bacteria - 210 m/g, coccal forms in a total sum of 0, Enterococcus, 106the fungi of the genus Candida 0, bifidobacteria 107lactobacilli 105lactic acid streptococci 107.

The above example of the complex treatment of acute intestinal infections and the prevention of its complications, the proposed method shows a high therapeutic effect, which cannot be achieved by known methods of treatment. The method is harmless, it causes no side effects, no contraindications, you can reduce the treatment time.

Results of treatment of patients with acute intestinal infections (% of patients with major clinical syndromes)
The research groupObstipationDiarrhoealDyspeptic
3 dayday 7day 143 day7 den the day 143 dayday 7day 14
The control group (baseline treatment)37,113,8080,038,0the 4.754,716,68,5
Experimental group (complex treatment using herbal)16,50060,015,0030,010,0the 4.7

1. The method of treatment of acute intestinal infections, including basic therapy with the use of antibiotics, rehydration therapy, sorbents, symptomatic therapy, the tincture of the collection of medicinal plants containing rhizome tormentil, sage leaves, yarrow herb within 3 weeks after basic treatment, characterized in that from the first day of the disease within 10 days of basic therapy prescribed fee, which additionally contains the herb, rhizome with the roots of Valerian, an herb, peppermint leaf, fennel fruit and the bark of buckthorn in a ratio of components in parts 2:2:2:2:2:2:2:2:1 accordingly, 1/3 Cup 3 times a day, 30 minutes before a meal.

2. The method according to claim 1, which includes antibiotic therapy antibiotics - Amazin 400 mg/su is, the sulfonamides - the appointment of 2.0-4.0 g/day for 7 days, as rehydration therapy - saline, Trisol/drip in the amount of 1200-800 ml per day for 5 days, then regidron per os to 1 l per day for 5 days, as sorbents - POLYSORB of 1.0-2.0 g of the powder in suspension 3 times a day for 10 days, and as symptomatic therapy introduction antispasmodics - no-Spa for the first 2-3 days/m 2%solution 3 times a day, then per os at 0.18 g/day for 7 days and antipyretics - 50%solution of dipyrone and 1%solution Dimedrol 2 times a day for 2-3 days.



 

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