Uterine lavage technique
FIELD: medicine; gynecology.
SUBSTANCE: puerpera with puerperal subinvolution of uterus and/or puerperal endometritis is instrumentally examined for uterine bulk within neck greatest extension. Puerpera's body is positioned so that upper end of uterus fundus is located lower than low end of uterine neck opening till uterine cavity is completely filled with blood. Catheter is pre-inserted to uterine neck fundus. Then uterine cavity is filled with warmed-up +42 - +45°C solution of mixed 0.9% sodium chloride and 3% hydrogen peroxide, through catheter. Then uterine cavity is US examined for position of thick objects and catheter, which is consistently brought to contact each thick object within point of attachment to uterus, followed with renewed introduction of solution. This procedure is accompanied with longitudinal forward motions of catheter with transverse vibration is introduced to this points to provide objects torn away from uterine wall until complete removal of all thick objects from uterine cavity. Then uterine cavity is filled with warmed-up +42 - +45°C dehydrated silicone gel soaked with % hydrogen peroxide in amount exceeding half of cavity bulk.
EFFECT: provided non-traumatic clearance of thick blood bunches from uterine cavity; clearance of amniotic sac under visual control; stimulation of coagulating system; prolonged disinfection of uterine cavity walls and activated contractive activity of uterus.
The invention relates to medicine, in particular to obstetrics and gynecology, and can be used to treat the puerperium with postnatal subinvolution of the uterus.
Known way to stop uterine bleeding, including the definition of instrumental methods of volume of the uterine cavity and the greatest length from her neck, the fixation body postpartum women and adolescent girls in the position in which the top edge of the bottom of the uterine cavity is below the bottom edge of the hole in the cervix prior to complete filling of the uterine cavity blood, the introduction through the opening in the neck in the region of the bottom cavity warmed up to +42 to +45°With dry silicone gel is soaked in an equal volume solution of 3% hydrogen peroxide in excess of half of the volume of the cavity, (EN 2288656 C1, 2006, Urakova N.A., Urakov A.L., Sokolova, NV, Kasimov A.D. Way to stop uterine bleeding).
The disadvantage of this method is the delay of infected residues fetal membranes and blood clots in the uterus, because the method provides not remove dense biological objects (fetal membranes, fluid and clotted blood from the uterus), and delay it. This method provides disinfection of the inside of the uterus only the liquid portion of blood, but did not provide effective disinfection located in the cavity dense bi is a Boolean object, such as infected remnants of the fetal membranes and the blood clots, adjacent to the inner surface of the uterine cavity. The method does not provide the disinfection portion of the inner cavity surface covered by these dense objects. Moreover, the method enhances their diligence to the walls of the cavity and provides long-term fixed contact them with each other, as is the increase in volume of the liquid portion of blood due to the formation of her peoplefrom, which, in turn, eliminates the imminent removal of these infected biological objects outside, and they facilitate the incubation of infectious agents in a confined space, and infection of the uterine wall that leads to the development of postpartum endometritis. Therefore, the method has a low efficiency and safety in postpartum subinvolution of the uterus, complicated by infection of the contents of the uterine cavity, including blood clots and the remnants of the fetal membranes, despite the hemostatic effect, because it is not conducive to rapid destruction of infected dense biological objects from the uterus to the outside, promotes infection of the uterine wall and does not prevent the development of endometritis.
The purpose of the invention is improving the efficiency and safety of treatment of parturient women with postpartum subinvolution Mat and by increasing the accuracy of removing residual fetal membranes and blood clots.
The essence of the proposed method uterine lavage, including the definition of instrumental methods of volume of the uterine cavity and the greatest length from her neck, the fixation body postpartum women and adolescent girls in the position in which the top edge of the bottom of the uterine cavity is below the bottom edge of the hole in the cervix prior to complete filling of the uterine cavity blood, the introduction of the catheter through the opening in the neck in the region of the bottom cavity warmed up to +42 to +45°With dry silicone gel is soaked in an equal volume solution of 3% hydrogen peroxide in excess of half of the volume of the cavity, is that pre - in the region of the fundus of the uterine cavity catheter and with it warmed up to +42 to +45°With a solution consisting of 0.9% sodium chloride solution and 3% hydrogen peroxide, to full fill the cavity formed in it foam, then using ultrasound visualize the position of solid objects and the catheter in the cavity, is consistently down the catheter to contact with each dense object in the place of its attachment to the uterine wall, and then resume the introduction of the solution, the catheter longitudinal translational movement transverse oscillations introduced in this place before the separation of the object from the wall and until the complete removal of all solid objects from the uterus.
Will prefix is inoe introduction to the area of the fundus of the uterine cavity of the catheter and using it warmed up to +42 - +45°With a solution consisting of 0.9% sodium chloride solution and 3% hydrogen peroxide leads to the formation of foam from the liquid portion of blood in a cavity of the uterus. When the foam begins to form in the bottom of the cavity. Foaming blood increases in volume and is pushed out through the opening in the cervix. Full filling the uterine cavity with a solution consisting of 0.9% sodium chloride solution and 3% hydrogen peroxide, excludes the presence and accumulation of liquid in the cavity blood, pus and lohii, because in the presence of hydrogen peroxide they foaming. The introduction of the hydrogen peroxide solution of 0.9% sodium chloride deprives the solution hypoosmolality and achieving isoosmotic level, namely the values osmoticnosti about 280 mOsm/l of water, which increases the security of finding a solution into the uterine cavity. Using the specified solution warmed eliminates cooling and hypothermia of the uterus, development of respiratory infectious diseases, inhibition of thrombus formation and reduction of contractile activity of smooth muscle. Heating the solution to a level of +42 to +45°excludes burns and provides the maximum possible stimulation of a protective immune forces of the blood coagulation system and the contractile elements of the smooth muscle formation in the uterus and in its cavity, which increases the efficiency and safely is any way in postpartum subinvolution of the uterus, complicated by infection of the contents of the uterine cavity. The use of ultrasound allows for efficient and safe to visualize the uterus and the contents of the cavity, especially in the formation in it of foam that is due to the gas bubbles reduce the density of a liquid content and increases with an ultrasound contrast dense (without gas bubbles) of biological objects, such as the remnants of the fetal bladder, blood clots, and also the catheter.
Consistent sizing catheter to the places of attachment of each solid object against the wall of the uterus and resume when the solution provides efficient mechanical and hydrodynamic effects of the spray solution and foam, as well as the end of the catheter in dense biological objects to their full separation from the uterine wall and avoiding injury to the uterus. Occurs during this longitudinal movement of the catheter with the transverse oscillations increase the area of mechanical and hydrodynamic effects on the attachment of dense objects to the wall of the uterus and increase the efficiency of their separation from it. The implementation of these actions under ultrasound until the complete removal of all heavy objects from the uterine cavity ensures the effectiveness and safety of the method by removing all infected dense biologicalsciences of the cavity.
Example. The patient Century. 23 years due to lack of efficacy basic intensive medical therapy regarding incurred by it after term labor postpartum subinvolution of the uterus and postpartum endometritis, on the 4th day after birth using ultrasound determined the volume of the uterine cavity (it was equal to 20 cm3and the greatest length from the cervix (the length of the cavity was set to 10 cm). Then the puerperal placed in a gynaecological chair and under ultrasound fixed body in the position in which the upper edge of the uterine cavity has dropped below the lower edge of the hole in the cervix prior to complete filling of the uterine cavity lahiani and blood. After 6 cm3crystalline anhydrous silica gel from diapers company "Procter & Gamble" has infiltrated the 6 ml solution of 3% hydrogen peroxide, the resulting gel was collected in a syringe connected to the catheter, heated them up to +45°and introduced in the region of the fundus of the uterus through the catheter to a depth of 10 cm in a few seconds the uterine cavity was filled with peopletravel. The expiration of the uterus lohii streaked with scarlet red blood decreased significantly, but not completely stopped until the following day. Bleeding from uterine lochia had a bad smell, clinical signs of endometritis has not decreased. On this basis b is lo made an assumption about the presence in the uterus of infected residues fetal membranes or blood clots and it was decided to remove them from the cavity together with peopletravel. To do this, under ultrasound control in the region of the fundus of the uterine cavity was entered catheter and with it warmed up to +43°With a solution consisting of 0.9% sodium chloride solution and 3% hydrogen peroxide, to full fill the cavity with foam. Then, using ultrasound cavity found dense object that is attached to the uterine wall and projecting into the cavity one oscillating end, and put into the cavity of the catheter. Under ultrasound summed up the catheter to contact with the identified object in the place of its attachment to the uterine wall and resumed the introduction of the solution, observing the object. Because the object remains attached to the uterine wall, then under the control of the ultrasound catheter longitudinal translational movement transverse oscillations introduced under his base and he broke away from the wall. After this object has been removed from the uterine cavity, the introduction of the solution was stopped. After that held ultrasonic revision of the contents of the cavity and confirmed the absence of any solid objects.
Then he fixed the body postpartum women and adolescent girls in the position in which the upper edge of the uterine cavity has dropped below the lower edge of the hole in the cervix, waited for the moment to full fill the uterine cavity blood and introduced in the region of its bottom with a syringe and catheter 12 ml of warmed up to 45°With silica gel impregnated equally the m volume of 3% hydrogen peroxide. After a few seconds, the uterine cavity was filled with peopletravel. The expiration of the uterus stinking lohii streaked with blood decreased significantly, and in the evening ceased completely. Clinical symptoms of postpartum endometritis decreased. Bacteriological analysis of the contents of the uterus, held on the 6th day, confirmed the absence of infections by pathogenic microflora. If this were found clinical signs of nephritis puerperal endometritis. On the 7th day after birth symptoms subinvolution of the uterus and postpartum endometritis disappeared. Held on this day ultrasound examination of the cavity of the uterus showed that its volume was reduced to 2.1 cm3. These data confirmed the completion of the process of involution of the uterus. The patient was discharged on the 8th day in a satisfactory condition.
The way uterine lavage, including the definition of instrumental methods of volume of the uterine cavity and the greatest length from her neck, the fixation body postpartum women and adolescent girls in the position in which the top edge of the bottom of the uterine cavity is below the bottom edge of the hole in the cervix prior to complete filling of the uterine cavity blood, the introduction of the catheter through the opening in the neck in the region of the bottom cavity heated to 42 - 45°With dry silicone gel, propiano is about an equal volume solution of 3%hydrogen peroxide in volume, over half of the volume of the cavity, wherein the pre in the region of the fundus of the uterine cavity catheter and with it warmed up to 42 - 45°With a solution consisting of 0.9% sodium chloride solution and 3% hydrogen peroxide, to full fill the cavity formed in it foam, then using ultrasound visualize the position of solid objects and the catheter in the cavity, is consistently down the catheter to contact with each dense object in the place of its attachment to the uterine wall, and then resume the introduction of the solution, the catheter longitudinal translational movement transverse vibrations enter in this place before the separation of the object from the wall and up to the complete removal of all solid objects from the uterus.
FIELD: medicine; surgery.
SUBSTANCE: for this purpose in case of surgery medicinal agent "Ferrovir" is intramuscularly injected as 1.5% solution in dosage 5.0 ml 2 times a day during 10 days. Conservative ferrovir-based therapy of destructive pancreatitis in specified dosage and injection rate is prescribed in 3 days following enzyme toxemia and systemic inflammatory reaction syndrome relief.
EFFECT: complex normalisation of cytokine state symptoms even against acute destructive process, and reduction of suppurative complication rate.
2 ex, 1 dwg
SUBSTANCE: invention relates to prevention and treatment of acute pancreatitis after the endoscopic papillosphincterotomy and retrograde pancreatocholangiography. For this purpose, in fybroduodenoscopy, the submucous depot of anesthetic with antibiotic, with ratio 5:1, is created by injecting the drugs via the instrumental endoscope canal with use of the endoscopic injector, 5-10 mm off fistula or papillotomy aperture at 9 o'clock. At 3 o'clock by dial plate, the submucous depot of spasmolytic and antihistamine drug, at 1:1 correlation, is created. In 12-24 hours, the procedure is repeated until the clinical effect is achieved. The lymphotropic anesthetics are used: 0.5% 10 mL Novocain, 0.5% 10 mL Lidocain. The spasmolytics are used: 2% 2 mL No-Spa, 0.2% 2 mL Platyphyllin hydrotartrate. The antibiotic is used: 4% 2 mL Gentamycin. 1% 2 mL Dimedrol is used as the antihistamine drug.
EFFECT: method provides simultaneous rapid relief of pain syndrome, cramps of sphincter of major duodenal papilla; prevents tissues edema with little volume of medicines.
3 ex, 2 dwg, 5 cl
SUBSTANCE: method involves smearing 10% Indomethacin ointment over duodenal mucous membrane as 3 cm long thin layer outward from the wound immediately after duodenotomy.
EFFECT: suppressing inflammatory phenomena in duodenal wall; preventing pancreatic exocrine secretion regulation disorder; preventing intraductal hypertension of pancreas.
FIELD: medicine, surgery gastroenterology, intensive therapy.
SUBSTANCE: on background of conventional intensive therapy of pancreatitis and before surgery operation method involves carrying out intramuscular administration of galavite. In stage of enzyme toxemia galavite is administrated in the dose 200 mg, 1-2 times per 24 h. Then in the first 24 h after surgery operation - in the single dose 300 mg per 24 h. In the following days - in the dose 100 mg per a day up to disappearance of symptoms of inflammatory response and normalizing level of blood cytokines. Then treatment is continued by administration of galavite in the dose 100 mg, once per 72 h. Method provides effective treatment, reducing amount of complications, lethality, number of repeated sanitations, decreasing number of repeated operations and decreasing hospitalization period of patients based on correction of processes SIRS and CAPS in this group of patients. Invention can be used in treatment of patients with acute destructive pancreatitis.
EFFECT: enhanced effectiveness of treatment.
7 tbl, 5 dwg, 2 ex
SUBSTANCE: method involves excluding provoking factors influence, administering diet, carrying out substitution therapy with enzymes, inhibiting pain syndrome, applying infusion therapy, introducing anabolic steroids, phosphodiesterase inhibitors, anti-diarrhea drugs and antioxidants like Freedox and Emoxipin. Perfluorane is introduced daily at a dose of 2 ml/kg, Freedox at a dose of 3-9 mg/kg and Emoxipin at a dose of 3 mg/kg once a day not less than 3 days long but not longer than 7 days.
EFFECT: provided combined oxygenation normalization, metabolic cell control and phospholipid composition of cell membranes; accelerated pain syndrome alleviation.
FIELD: medicine, surgery.
SUBSTANCE: invention relates to treatment and prophylaxis of acute pancreatitis in humans and agent used for this aim. Agent represents serum against true viper venom. Method involves preliminary administration in a patient of anti-histamine preparation and in 30 min serum is administrated. Serum is diluted with physiological solution and administrated by intravenous route by drops being firstly in dose 0.1 ml, then in 10 min in dose 0.25 ml, and then in 15 min - the remainder dose. In treatment of acute pancreatitis method involves administration of serum in dose 450 AE diluted in 300 ml of physiological solution in the first day, 300 AE of serum diluted in 200 ml of physiological solution in the second day and 150 AE of serum diluted in 100 ml of physiological solution in the third day. Prophylaxis of acute pancreatitis in humans is carried out by administration of 150 AE of seum diluted in 100 ml of physiological solution. Invention provides inhibition of enzymatic activity of pancreas that enhances effectiveness of treatment in case of severe forms of pancreatitis in edema and necrosis stage also, and promotes to prophylaxis of acute pancreatitis after direct surgery operations on pancreas and carrying out endoscopy in cholangiopancreatography procedure.
EFFECT: enhanced effectiveness of treatment and prophylaxis, valuable medicinal properties of agent.
3 cl, 4 ex
SUBSTANCE: composition comprises pancreatine as active ingredient, lactose, calcium stearate, filler and coating capsule soluble in intestine composed of acetylphthalyl cellulose, titanium dioxide, binding agent and acid red and sliding. Potato starch is used is used as filler. Nucleus additionally has sugar invention in 1 : (1.8-2) proportion to lactose, Copolyvidon. The coating capsule has polyethyleneoxide as binding agent.
EFFECT: high stability in acid medium; enhanced effectiveness of treatment.
FIELD: medicine, surgery.
SUBSTANCE: one should introduce about 2-4 mg cyclophosphan diluted in 10-20 ml 0.9%-NaCl solution into cystic cavity at exposure of 15 min followed by aspiration. The innovation provides efficient and safe cystic obliteration due to cyclophosphan's capacity to decrease pancreatic tissue exudation and proliferation.
EFFECT: higher efficiency of therapy.
FIELD: organic chemistry, medicine, hormones.
SUBSTANCE: invention describes imidazole derivatives of the formula (I) , racemic-diastereomeric mixtures and optical isomers, pharmaceutical salts wherein ---- represents an optional bond; R1 represents hydrogen atom (H), -(CH2)m-C(O)-(CH2)m-Z1, -(CH2)m-Z1; R2 represents hydrogen atom (H), or R1 and R2 are joined with nitrogen atoms to which they are bound forming compounds represented by formulae (Ia), (Ib) or (Ic) wherein R3 represents -(CH2)m-E-(CH2)m-Z2; R4 represents hydrogen atom (H) or -(CH2)m-A1; R5 represents (C1-C12)-alkyl, (C0-C6)-alkyl-C(O)-NH-(CH2)m-Z3 and optionally substituted phenyl; R6 represents hydrogen atom (H); R7 represents (C1-C12)-alkyl or -(CH2)m-Z4; m = 0 or a whole number from 1 to 6; n is a whole number from 1 to 5. Proposed compounds bind with subtypes of somatostatin receptors selectively.
EFFECT: valuable properties of compounds.
20 cl, 13776 ex
FIELD: organic chemistry, pharmacy, biochemistry.
SUBSTANCE: invention relates to new substituted 2H-pyrano[2,3-c] of the general formula (1) eliciting ability to inhibit activity of protein kinase. In the general formula (1) X represents oxygen atom or group NR3; R1 represents group -C(O)R4, optionally substituted and optionally condensed azaheterocycle; R2 represents optionally substituted hydroxyl group or optionally substituted amino-group; R3 represents hydrogen atom or inert substitute meaning optionally substituted low- or non-reactive radical including such as (C1-C7)-alkyl, (C2-C7)-alkenyl, (C2-C7)-alkynyl, (C1-C7)-alkoxy-group, (C7-C12)-aralkyl, heterocyclylalkyl, (C7-C12)-alkaryl, (C3-C10)-cycloalkyl, (C3-C10)-cycloalkenyl, phenyl, aryl, (C2-C12)-alkoxyalkyl, (C2-C10)-alkylsulfinyl, (C2-C10)-alkylsulfonyl, -(CH2)-O-(C1-C7-alkyl), -(CH2)m-N(C1-C7-alkyl)n, aryloxyalkyl, heterocyclyl wherein m and n have value from 1 to 7; R4 represents optionally substituted amino-group or hydrogenated optionally substituted azaheterocycle. Also, invention relates to combinatory and focused libraries consisting of compounds of the present invention and designated for the search of compound-hits and compound-leaders prepared by screening of these libraries for using in preparing medicinal agents.
EFFECT: valuable medicinal properties of compounds.
8 cl, 2 tbl, 6 ex
SUBSTANCE: method involves removing hematoma from cavity by means of puncture needle. Then, 3% hydrogen peroxide solution is introduced into the cavity through the same needle in the amount of one-half taken blood volume and left for 3-5 min. Then, the hydrogen peroxide solution is removed and ozonized biological glue is introduced into the cavity in the amount equal to 1/4-1/3 of aspirated blood volume. The hematoma localization area pressed with tampon for 2-3 min.
EFFECT: reliable hemostasis; accelerated wound cleansing; improved recovery process.
FIELD: medicine, surgery.
SUBSTANCE: the present innovation refers to treating osseous cavity in patients with chronic post-traumatic osteomyelitis, so, after necrsequestrectomy one should irrigate an osseous cavity with aqueous solution of sodium chloride, then it is necessary to treat the cavity with 3%-hydrogen peroxide solution with subsequent removal of foam with 0.02%-chlorohexidine bigluconate aqueous solution. Then twice during 1 min it is necessary to treat osseous cavity with 0.9%-ozonized sodium chloride solution at ozone concentration being 9000-10000 mgl/l. After that, one should introduce the mixture of anti-infectious chemotherapeutic preparations along with ultrasound cavitation for 3 min at frequency of 40 kHz followed by treating the cavity with the flow of nitrogen monoxide for 5 min at concentration being 5000 mg/cu. m. The innovation enables to increase penetrating capacity of medicinal preparations due to matching the desired mode of cavitary treatment.
EFFECT: higher efficiency of antiseptic treatment.
FIELD: medicine; radiological diagnostics.
SUBSTANCE: method can be used for diagnosing endometriosis of uterus and for estimating state of post-operational scars of myometrium as well as for visualizing bases of subserous and submucous myomatous uterus nodes. Uterus cavity is filled with contrast matter. Hydrogen peroxide solution is used as contrast matter in non-toxic amount; solution is injected in bolus dosing. Before injection sizes of uterus cavity are measured additionally and expected limiting volume V of filling of uterus cavity is calculated from relation of V=0,1a1h2, where h is length of uterus cavity, and a1 is width of uterus cavity at bottom of uterus. In accordance with expected limiting volume of filling, amount of injected echo-contrast matter is chosen while taking its rejection along uterus tubes into account. Uterus cavity is filled in dosage-by-dosage to make sure that there is no drainage of matter trough uterus neck and limiting volume of filling of cavity is kept. Appearance of echo-contrast matter is scars of myometrium, in myometrium, onto parietal and visceral peritoneum is estimated at moment of injection of contrast matter or later.
EFFECT: improved precision of inspection.
4 l, 16 dwg, 4 ex
FIELD: medicine, diagnostics.
SUBSTANCE: the present innovation deals with functional radiation diagnostics of uterine tubes, ureters, bile-excretory pathways and so on. It is necessary to carry out ultrasound research, organ's echocontrasting technique, introduction of sterile hydrogen peroxide solution in nontoxic dosage followed finally by evaluation of the results obtained. Moreover, ultrasound research should be conducted under conditions of local intracavitary anesthesia, either due to endocavitary or transabdominal access in three stages. At the first stage one should fulfill organ's echocontrasting due to introduction of a contrast sound-conducting substance into organ's cavity, fix permeability of the latter into a hollow organ under testing, adjacent organs and cavities, detect the volume and structure of a hollow organ, the availability of pathological neoplasms and evaluate functional state of an organ. At the second stage, organ's echocontrasting should be fulfilled due to introducing a sterile hydrogen peroxide solution directly into a hollow organ, according to gaseous bubbles it is necessary to evaluate anatomical structures, the availability of pathological deviations and echocontrast movement. As for the third stage, it should be carried out about 3-6 min after removing a catheter out of the cavity, due to echocontrasting the organ with residual gaseous bubbles it is possible to evaluate the state of hollow organs according to physiological movement of bubbles along the hollow organ in real period of time followed by introduction of sterile hydrogen peroxide with the help of a catheter applied under conditions of local intracavitary anesthesia, concentration of hydrogen peroxide in solution should be equal to 0.30-0.33%. The innovation enables to detect different pathology of a hollow organ, evaluate both anatomical and physiological alterations in organs.
EFFECT: higher accuracy of detection.
4 cl, 8 ex
SUBSTANCE: method involves providing double-staged processing of physiological salt solution with ozone, first stage including bubbling of physiological salt solution with ozone-oxygen mixture having ozone concentration of 3 mg/l to 10 mg/l at ozonizer outlet end, and second stage including additionally introducing ozone-oxygen mixture into the same bottle under pressure of from 1.5 atm to 2.9 atm, said mixture having ozone concentration of from 6 mg/l to 10 mg/l.
EFFECT: increased time of keeping ozone in physiological salt solution.
3 tbl, 1 ex
FIELD: medicine, obstetrics, gynecology.
SUBSTANCE: due to instrumental technique one should pre-detect the volume of uterine cavity and its longest length against the cervix. Moreover, it is necessary to fix a woman's body in position at which the upper edge of uterine cavity bottom is below against the lower edge of uterine cervical opening till the moment of complete filling in uterine cavity with blood. With the help of a catheter one should introduce medicinal preparation heated up to +42- +45° C into uterine cavity through an opening in uterine cervix into area of cavitary bottom at the volume exceeding the half of cavitary volume. Moreover, as the above-mentioned medicinal preparation it is necessary to apply dehydrated silicone gel impregnated with equal volume of 3%-hydrogen peroxide solution. The innovation enables to interrupt postpartum hypotonic uterine hemorrhage efficiently and safely.
EFFECT: higher efficiency.
FIELD: medicine, neurosurgery.
SUBSTANCE: one should prepare the bones of cranial fornix transplant for transplantation due to forming hollows at their external surface that don't penetrate a diploic plate. Then one should remove bone marrow due to applying 5%-hydrogen peroxide solution. Just before transplantation during operation it is necessary to sample recipient's bone marrow out of trabecular bone to fill in the hollows of the transplant prepared. The innovation enables to increase the quality of the applied transplant due to introducing osteogenesis-stimulating cells of bone marrow into the transplant.
EFFECT: higher efficiency.
FIELD: medicine, surgery.
SUBSTANCE: the present innovation deals with visualization of biliary excretion during laparoscopic cholecystectomy. For this purpose, one should introduce 10 ml 0.4%-indigo carmine blue solution intravenously, after cholecystectomy one should treat cholecyst bed with 3%-aqueous hydrogen peroxide solution diluted in 500 ml isotonic solution. Moreover, small open ducts should be stained into light-blue color, and additional ducts - into more intensive light-blue color. If necessary, the procedure mentioned should be repeated. The innovation provides the chance for qualitative implementation of electrocoagulation of biliary ducts and cholecyst bed and, thus, prophylaxis of biliary excretion in postoperational period.
EFFECT: higher efficiency.
FIELD: medicine, in particular agent for treatment of hepatitis, toxoplasmosis, cytomegaloviral infection and influenza.
SUBSTANCE: claimed agent contains physiological saline for intravenous administration, comprising hydrogen peroxide, 0.2 % riboxine solution and decoction of liquorice roots in specific ratio.
EFFECT: non-toxic and effective agent for treatment of abovementioned diseases.
SUBSTANCE: method involves covering gingival mucous membrane with screen substance like wax or photocurable Koferdamm before applying laser radiation treatment. Water or 30-35% aqueous hydrogen peroxide solution is sprayed over dental surface or bleaching gel diluted with hydrogen peroxide is applied. The dental surface is next exposed to continuous diode laser radiation with wavelength selected from bandwidth of 800-970 nm during 15-300 s. Laser radiation power density belongs to bandwidth of 10-100 W/cm2. Radiation energy dose is in the range of 40-3000 J with dose density being equal to 200-20000 J/cm2 diode laser power being equal to 2.8 W, light beam diameter being equal to 3.5-5 cm when being 1 to 2 mm far from the dental surface. When exposed to laser radiation, the dental surface is uniformly scanned with laser beam.
EFFECT: enhanced effectiveness and safety of the procedure.
6 cl, 4 tbl
SUBSTANCE: hepasol A in dosage 4.0-8.0 ml/kg and 5% glucose solution are injected separately in equal dosages 40 minutes before surgery. After main operation step is complete blood is microscopically tested for fat globules. In case 10 globules of size less than 5 mcm, or one or more globules of size more than 5 mcm are found totally within 8 microscopic field, test result is considered to be positive, and Hepasol A and 5% glucose solution introduction is prolonged. In case no globules found or those found are totally less than 10 in number of size less 5 mcm test result is considered to be negative, thus Hepasol A and 5% glucose solution introduction is stopped. Blood is repeatedly tested for fat globules in 12 hours after last introduction of Hepasol A. If positive test result for fat globules is registered, Hepasol A and 5% glucose solution introduction is recommenced, and in case double negative test result is registered, Hepasol A is not introduced.
EFFECT: method allows preventing of systemic fat embolism development in perioperative period.
2 tbl, 1 ex