Method of correction of human functional condition

FIELD: medicine; physiology and therapy.

SUBSTANCE: patient's cardiointervalograms are registered and analysed in real time mode. Respiratory movements are synchronised with own heart rate. Command information to man on inspiration-expiration is generated by microcontroller on basis of analysis of ongoing cardiointervalogram, and inspiration command is generated by microcontroller upon registration of cardiointervalogram's maximum and provided the time interval of analysis lockout is completed, when microcontroller's commands are pending even at extremum. Expiration command is generated upon registration of cardiointervalogram's minimum and the time interval of analysis lockout starts at expiration command with duration of three cardio cycles, or at inspiration command with duration of one cardio cycle.

EFFECT: method increases efficacy of systems of diagnostics and correction of human functional condition.

6 dwg

 

The invention relates to medicine, namely to the physiology and therapy, and can be used in systems of diagnostics and correction of human functional state.

Known "Method of functional physiological correction of the human condition and diagnosis in the process of correction" (patent RF №2221477), the essence of which is the visual representation of the patient's own cardiotocogram (kardiointervalogrammy) in real time while the patient examines cardiotocogram and synchronizes its respiratory movements with variations of their own heart rhythm: the higher the heart rate provides a breath, but at a lower heart rate exhale. This cardiorespiratory synchronization (training with biofeedback (BFB) cardiorespiratory system, cardiorespiratory biofeedback training) stimulates the vagus nerve, leading to relaxation of the patient. The disadvantage of this method is actively involved in the analysis of cardiotocograms patient, which reduces the degree of relaxation. The second disadvantage is the attachment of the patient (subject) to the monitor, which imposes limitations on the conditions of carrying out of sessions of biofeedback and complicates or even makes it impossible combination of sessions biological reverse the th connection with other types of active load on the body (physical, psychological and other).

The objective of the invention is to increase the efficiency effects on the autonomic nervous system ways cardiorespiratory synchronization with the organization of biological feedback by eliminating additional psychological burden on the patient in the form of analysis of their kardiointervalogrammy, as well as increasing the mobility of the entire complex cardiorespiratory synchronization for a combination of biofeedback sessions with other types of active load on the body by eliminating the mandatory visual communication of a patient with a complex.

The invention consists in the correction of human functional state by entering into a chain biofeedback microcomputer Registrar analyzer, which analyzes kardiointervalogrammy and in optimal time generates control commands to the breath, which obeys the patient.

Figure 1 shows the block diagram of complex cardiorespiratory synchronization; figure 2 presents kardiointervalogrammy belated response heart rate sauraseni (HR) inhalation (with "paradoxical" reaction); figure 3 shows the block diagram of the algorithm subroutine that provides the analysis of kardiointervalogrammy and the formation of governors with whom galow; figure 4 presents a comparison of actual schedules kardiointervalogrammy during the session cardiorespiratory biofeedback training of the proposed method and the method proposed in the prototype, one and the same person; figure 5 shows kardiointervalogrammy during the session cardiorespiratory biofeedback training of the proposed method in combination with a uniform load on the bike. Figure 6 presents kardiointervalogrammy when combined sessions cardiorespiratory biofeedback training with orthostatic breakdown.

The method is as follows. Person 1 impose the electrodes 2 microcomputer Registrar analyzer. Potentials electrocardiogram amplified biopotential amplifier 3, is filtered from the noise filter unit 4 and are fed to the analog input of the microcontroller 5, which allows you to digitize the signal, select RR-intervals, and then to register them in memory (block 7, figure 1), to analyze and, as a result of analysis, to generate control signals on the breath, which is coming to the unit issuing commands (section 6, figure 1). The power output of commands affects the hearing and / or vision, and / or tactile person, i.e. issues commands in the audio and / or visual and / or tactile form. Man obeys the commands and makes breathing magic cube MOV is I, which is inversely affect the RR-intervals (heart rate), i.e. the chain biofeedback is closed. To achieve maximum relaxation recommended posture lying and(or) with his eyes closed.

As you know, when you inhale RR-intervals are shortened relative to the original level (heart rate increases), and when you exhale RR-intervals are extended relative to the original level (heart rate decreases). The process monotonic decrease of RR-intervals on the breath for most healthy people, lasts about 4-7 seconds, and then, even with continued inhalation, RR-intervals start to increase. The process monotonic increase of RR-intervals on the exhale for most healthy people, lasts about 3-5 seconds (and is usually a faster process monotonic decrease of RR-intervals), and then, even with continued exhalation, RR-intervals begin to decrease. If at the moment of crossing the maximum kardiointervalogrammy change the phase of respiration, then comes the cardiorespiratory synchronization (the phenomenon of functional resonance cardiorespiratory system [1]) with maximum stimulation of the vagus nerve and relaxation of the patient. This phenomenon relies on the selected prototype, as well as a number of other similar techniques [2, 3]. However, the bi organization is logical feedback in these ways involves active involvement in the analysis of cardiotocograms patient, that reduces the degree of relaxation, and also forms the attachment of the patient (subject) to the monitor, and this imposes limitations on the conditions of carrying out of sessions of biofeedback. To address these shortcomings may input circuit biofeedback microcomputer Registrar analyzer, which analyzes kardiointervalogrammy and in optimal time generates control commands to the breath, which obeys the patient.

Practical tests how to use biofeedback evaluation kardiointervalogrammy patient microcomputer Registrar analyzer in real time showed that in some cases the nature of changes in RR-intervals during inhalation and exhalation is not subject to the above stated rule and the opposite occurs (the"paradoxical") reaction, in particular some people had a delayed reaction accelerations (ischemia) to the heart rhythm in the breath (exhale)that resulted after one extremum other extremes, not directly associated with the phenomenon of cardiorespiratory synchronization (functional response), and dependent on the individual characteristics of the response of heart rate on respiratory movements. Because of this microcomputer Registrar analyzer was incorrectly team. For the liquid is tion of this negative effect was introduced immediately issued for command block interval analysis, during which the presence of an extremum does not lead to the issuance of a management team. The duration of the interval, it is advisable to take approximately three cardiocycle after inhalation and one cardiac cycle after the command exhalation. This value is a compromise between the errors of the first and second kind, that is, between the pass extremum, due to the resonant properties of the cardiorespiratory system and false positives extremes. The difference in the duration of these two interlocking due to the different speeds of the processes of increase and decrease of RR-intervals (figure 2).

The block diagram of algorithm subroutines microcontroller, providing analysis of kardiointervalogrammy and the formation of control signals with respect to the interval presented in figure 3.

Figure 4 presents a comparison of cardiointervalogram received from the same person in the same conditions as described in the prototype (on the left in figure 4) and the proposed method (right in figure 4). According to subjective feelings, the depth of relaxation in the organization biofeedback proposed method is higher than with the organization of biological feedback method of the prototype. On objective data when cardiorespiratory synchronization method of the prototype averaged RR-intervals of ugliness of 0.75 to 0.87 (HR, respectively, decreased from 80 to 69 beats./min), and when cardiorespiratory synchronization method proposed average RR-interval was lengthened from from 0.76 to 1.05 with (HR, respectively, decreased from 79 to 57 beats./min), reflecting the greater relaxation of the patient and greater stimulation of the vagus nerve of the proposed method in comparison with the prototype. Similar results were obtained in other subjects.

The man in the proposed method, the organization of biological feedback plays a passive role, i.e. people just obey the commands microcomputer Registrar analyzer, and visual communication with technical devices is not required, sufficient audio connection. This allows to combine the sessions of biofeedback with other types of active load on the body (physical, psychological). Figure 5 presents an example of kardiointervalogrammy when combined sessions cardiorespiratory biofeedback training of the proposed method with a uniform load on the bike, and figure 6 presents kardiointervalogrammy when combined sessions cardiorespiratory biofeedback training with orthostatic breakdown.

Thus, the input into the circuit biofeedback microcomputer Registrar analyzer, which analyzes kardiointervalogrammy and in optimal time generates control commands to the breath-idoh, which obeys the patient, eliminates additional psychological burden on the patient in the form of analysis of their kardiointervalogrammy, and also eliminates the mandatory visual relationship of the patient with a technical device that allows you to achieve greater relaxation of the patient, to improve the efficiency effects on the autonomic nervous system ways cardiorespiratory synchronization with the organization of biological feedback, and also to increase the mobility of the entire complex cardiorespiratory synchronization for a combination of biofeedback sessions with other types of active load on the body. Enter in the routine analysis of extrema of interlocking analysis allows to take into account the individual reaction accelerations (ischemia) to the heart rhythm in the breath (exhale) with the advent followed by one extremum of kardiointervalogrammy other extremes, not directly associated with the phenomenon of cardiorespiratory synchronization (functional response) and which is in this case the noise.

Sources of information

1. Wasilla Mrs x, Zingerman A., Konstantinov M.A. Study the resonance characteristics of the cardiovascular system. //Human physiology, 1983. V.9, No. 2. S.257-265.

2. RF patent №2190952. Method for the treatment of opium addiction, burdened neurocytol the Torno dystonia, adolescents in the acute period / Yakovlev NM, Smetankin A.A. Publ. 2002.10.20.

3. Auth. St. USSR №1745200. The method of functional correction of blood pressure/ Gandarewa L.N., Vasilevsky N.N., Seisenbekov TERMS and others, Publ. 1992.07.07.

The method of functional correction of the human condition, including the registration and analysis of kardiointervalogrammy patient in real-time and synchronization of breathing with oscillations own heart rhythm: the breath is when you register the maximum kardiointervalogrammy, and the exhalation is performed when registering the minimum kardiointervalogrammy, characterized in that commands breath-person forms a microcontroller based on the analysis of the current kardiointervalogrammy, and the breath is issued by the microcontroller when registering maximum kardiointervalogrammy and provided the time interval of analysis, during which the microcontroller does not issue commands even in the presence of an extremum, and the exhalation is issued at check minimum kardiointervalogrammy and provided the time interval of analysis, with the time interval of analysis begins during the team's inspiration with a duration of three cardiac cycle or exhalation with a duration of one cardiocycle.



 

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